This option discusses the molecular and cellular mechanisms that underlie the aetiology of several human diseases, focussing on cardio-metabolic diseases. 

This option is assigned to block S2-B. There are normally 3 hours of teaching on Tuesdays, which may be split over more than one session. 

None.

The course will be assessed by a 2-hour examination (75%) and in-course assessment consisting of a written review of a scientific paper (25%).

Reassessments are normally available for all courses, except those which contribute to the Honours classification. For non Honours courses, students are offered reassessment in all or any of the components of assessment if the satisfactory (threshold) grade for the overall course is not achieved at the first attempt. This is normally grade D3 for undergraduate students and grade C3 for postgraduate students. Exceptionally it may not be possible to offer reassessment of some coursework items, in which case the mark achieved at the first attempt will be counted towards the final course grade. Any such exceptions for this course are described below. 

The aim of this course is to introduce students to current hypotheses concerning the biochemical and cellular processes which lead to individual disease states and to defined groups of diseases. The course will discuss experimental models of disease and the generation of therapeutic reagents.

By the end of the course, students will be able to: 

■ Critically discuss the molecular and cellular mechanisms that underlie human cardiometabolic diseases;

■ Interpret experimental data concerning the molecular and cellular mechanisms that regulate human health in the context of cardiometabolic diseases.

Students must submit at least 75% by weight of the components (including examinations) of the course's summative assessment.