In Human Genetics and Molecular Genetics, research aims to understand the ways in which variation in genes contributes to human traits and disorders. Both approaches are a focus of considerable research effort worldwide and this field garners a lot of interest from medical practitioners and public alike. Students taking this option will be exposed to examples of cutting-edge approaches in modern molecular genetics and post-genome science taught by active researchers and practitioners. 

This option is assigned to block S2-D. There will normally be one or two sessions of between 1 and 3 hours each on a Friday. 

None

The course will be assessed by a 2-hour examination (70%) and in-course assessment (30%), both of which will comprise a mixture of problem questions and mini-essay questions. The in-course assessment will comprise a single component and will be delivered either as a take-home assessment or as a timed test with preparation allowed beforehand. 

Reassessments are normally available for all courses, except those which contribute to the Honours classification. For non Honours courses, students are offered reassessment in all or any of the components of assessment if the satisfactory (threshold) grade for the overall course is not achieved at the first attempt. This is normally grade D3 for undergraduate students and grade C3 for postgraduate students. Exceptionally it may not be possible to offer reassessment of some coursework items, in which case the mark achieved at the first attempt will be counted towards the final course grade. Any such exceptions for this course are described below. 

The aims of this course are to foster: 

■ understanding of the principles underlying human genetics and their application in modern approaches to studying genetic disorders and traits;

■ awareness of the impact of genetics on human lives.

By the end of this course, students will be able to:

■ Discuss and critically appraise the current state of understanding of relevant topics in the field of human genetics and human molecular genetics, with specific focus on:

■ Data interpretation;

■ Human genomic variation and how it relates to the genetic basis for a range of human traits and disorders;

■ Models of human genetic disease;

■ Genetics in the clinic and in society and therapeutic options for genetic disorders; 

■ Use the scientific literature to evaluate evidence supporting hypotheses in the field of human genetics;

■ Critically discuss, evaluate and analyse data including that of a numerical and statistical nature. 

Students must submit at least 75% by weight of the components (including examinations) of the course's summative assessment.