2016

Colloby, S. J., Field, R. H., Wyper, D. J., O'Brien, J. T. and Taylor, J.-P. (2016) A spatial covariance (123)I-5IA-85380 SPECT study of α4β2 nicotinic receptors in Alzheimer's disease. Neurobiology of Aging, 47, pp. 83-90. (doi: 10.1016/j.neurobiolaging.2016.07.017) (PMID:27565302)

Colloby, S. J., McKeith, I. G., Burn, D. J., Wyper, D. J., O'Brien, J. T. and Taylor, J.-P. (2016) Cholinergic and perfusion brain networks in Parkinson disease dementia. Neurology, 87(2), pp. 178-185. (doi: 10.1212/wnl.0000000000002839) (PMID:27306636) (PMCID:PMC4940066)

2010

Cavanagh, J. , Patterson, J., Pimlott, S. , Wyper, D. and Dewar, D. (2010) SSRI antidepressants do not confound single photon emission computed tomography (SPECT) imaging studies using the α4β2 nicotinic acetylcholine receptor [123I]5-I-A85380 ligand: In vivo and in vitro evidence. Synapse, 64(2), pp. 111-116. (doi: 10.1002/syn.20705) (PMID:19771591)

Colloby, S.J., Perry, E.K., Pakrasi, S., Pimlott, S.L., Wyper, D.J., McKeith, I.G., Williams, E.D. and O'Brien, J.T. (2010) Nicotinic I-123-5IA-85380 single photon emission computed tomography as a predictor of cognitive progression in alzheimer's disease and dementia with Lewy bodies. American Journal of Geriatric Psychiatry, 18(1), pp. 86-90. (doi: 10.1097/JGP.0b013e3181b972aa)

Cavanagh, J. , Paterson, C., McLean, J., Pimlott, S. , McDonald, M., Patterson, J., Wyper, D. and McInnes, I. (2010) Tumour necrosis factor blockade mediates altered serotonin transporter availability in rheumatoid arthritis: a clinical, proof-of-concept study. Annals of the Rheumatic Diseases, 69(6), 1251-U367. (doi: 10.1136/ard.2009.107912)

2009

Knol, R.J.J., De Bruin, K., Van Eck-Smit, B.L.F., Pimlott, S.L. , Wyper, D.J. and Booij, J. (2009) In vivo [123I]CNS-1261 binding to D-serine-activated and MK801-blocked NMDA receptors: A storage phosphor imaging study in rats. Synapse, 63(7), pp. 557-564. (doi: 10.1002/syn.20629)

Lewis, D., Champion, S. , Dewar, D. , Honey, G., Gross, J., Robichaud, A., Welch, A., Wyper, D. and Pimlott, S. (2009) Characterisation of Novel Histamine H3 receptor tracers for SPECT. Journal of Labelled Compounds and Radiopharmaceuticals, 52(S1), S381. (doi: 10.1002/jlcr.1646)

McLean, J., Brennan, D., Wyper, D.J., Condon, B., Hadley, D.M. and Cavanagh, J. (2009) Localisation of regions of intense pleasure response evoked by soccer goals. Psychiatry Research: Neuroimaging, 171(1), pp. 33-43. (doi: 10.1016/j.pscychresns.2008.02.005)

2008

O’Brien, J. T., Colloby, S. J., Pakrasi, S., Perry, E. K., Pimlott, S. L. , Wyper, D. J., McKeith, I. G. and Williams, E. D. (2008) Nicotinic α4β2 receptor binding in dementia with Lewy bodies using 123I-5IA-85380 SPECT demonstrates a link between occipital changes and visual hallucinations. NeuroImage, 40(3), pp. 1056-1063. (doi: 10.1016/j.neuroimage.2008.01.010) (PMID:18295510))

Colloby, S.J., Pakrasi, S., Perry, E.K., Pimlott, S.L. , Wyper, D.J., Williams, E.D., McKeith, I.G. and O'Brien, J.T. (2008) The effects of donepezil on nicotinic receptor status in dementia: a ¹²³I-5IA-85380 SPECT study. Journal of Neurology, Neurosurgery and Psychiatry, 79(4), pp. 485-487. (doi: 10.1136/jnnp.2007.121780)

Pimlott, S. L. , Stevenson, L., Wyper, D. J. and Sutherland, A. (2008) Rapid and efficient radiosynthesis of [I-123]I-PK11195, a single photon emission computed tomography tracer for peripheral benzodiazepine receptors. Nuclear Medicine and Biology, 35(5), pp. 537-542. (doi: 10.1016/j.nucmedbio.2008.02.013)

Terrière, E. et al. (2008) α4β2-nicotinic receptor binding with 5-IA in Alzheimer’s disease: methods of scan analysis. Neurochemical Research, 33(4), pp. 643-651. (doi: 10.1007/s11064-007-9517-4)

2007

O'Brien, J.T., Colloby, S.J., Pakrasi, S., Perry, E.K., Pimlott, S.L. , Wyper, D.J., McKeith, I.G. and Williams, E. (2007) Alpha4beta2 nicotinic receptor status in Alzheimer's disease using 123I-5IA-85380 single-photon-emission computed tomography. Journal of Neurology Neurosurgery and Psychiatry, 78(4), pp. 356-362. (doi: 10.1136/jnnp.2006.108209) (PMID:17135460) (PMCID:PMC2077777)

Pimlott, S. L. , Piggott, M., Patterson, J., Cavanagh, J. and Wyper, D. J. (2007) SPECT imaging of the α4β2 nicotinic receptor using [5-¹²³I]A85380. Journal of Labelled Compounds and Radiopharmaceuticals, 50(5-6), pp. 350-353. (doi: 10.1002/jlcr.1192)

2006

O'Brien, J. T., Colloby, S. J., Pakrasi, S., Perry, E. K., Pimlott, S. L. and Wyper, D. J. (2006) Measurement of the α4β2 nicotinic receptor in vivo in Alzheimer's disease with 123I–5IA–85380 SPECT. Alzheimer's Association 10th International Conference on Alzheimer's Disease and Related Disorders, Madrid, Spain, 15-20 Jul 2006. S677. (doi: 10.1016/j.jalz.2006.05.2264)

Pimlott, S.L. , Piggott, M., Ballard, C., McKeith, I., Perry, R., Kometa, S., Owens, J., Wyper, D. and Perry, E. (2006) Thalamic nicotinic receptors implicated in disturbed consciousness in dementia with Lewy bodies. Neurobiology of Disease, 21(1), pp. 50-56. (doi: 10.1016/j.nbd.2005.06.008) (PMID:16023355)

2004

Pimlott, S.L. , Piggott, M., Owens, J., Greally, E., Court, J.A., Jaros, E., Perry, R.H., Perry, E.K. and Wyper, D. (2004) Nicotinic Acetylcholine Receptor Distribution in Alzheimer's Disease, Dementia with Lewy Bodies, Parkinson's Disease, and Vascular Dementia: In Vitro Binding Study Using 5-[125I]-A-85380. Neuropsychopharmacology, 29, pp. 108-116. (doi: 10.1038/sj.npp.1300302) (PMID:12955099)

2003

Pimlott, S.L. , Owens, J. and Wyper, D. (2003) Novel SPECT receptor ligands for the investigation of dementia. In: Ebmeier, K.P. (ed.) SPECT in Dementia. Series: Advances in Biological Psychiatry, 22. S. Karger AG, pp. 95-114.

Brown, D., Chisholm, J. A., Owens, J., Pimlott, S. , Patterson, J. and Wyper, D. (2003) Acetylcholine muscarinic receptors and response to anti-cholinesterase therapy in patients with Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging, 30(2), pp. 296-300. (doi: 10.1007/s00259-002-1028-6) (PMID:12552349)

2000

Benamer, H. T.S., Patterson, J., Wyper, D. J., Hadley, D. M., Macphee, G.J.A. and Grosset, D. G. (2000) Correlation of Parkinson's disease severity and duration with 123I-FP-CIT SPECT striatal uptake. Movement Disorders, 15(4), pp. 692-698. (doi: 10.1002/1531-8257(200007)15:4<692::AID-MDS1014>3.0.CO;2-V) (PMID:10928580)

Articles

Colloby, S. J., Field, R. H., Wyper, D. J., O'Brien, J. T. and Taylor, J.-P. (2016) A spatial covariance (123)I-5IA-85380 SPECT study of α4β2 nicotinic receptors in Alzheimer's disease. Neurobiology of Aging, 47, pp. 83-90. (doi: 10.1016/j.neurobiolaging.2016.07.017) (PMID:27565302)

Colloby, S. J., McKeith, I. G., Burn, D. J., Wyper, D. J., O'Brien, J. T. and Taylor, J.-P. (2016) Cholinergic and perfusion brain networks in Parkinson disease dementia. Neurology, 87(2), pp. 178-185. (doi: 10.1212/wnl.0000000000002839) (PMID:27306636) (PMCID:PMC4940066)

Cavanagh, J. , Patterson, J., Pimlott, S. , Wyper, D. and Dewar, D. (2010) SSRI antidepressants do not confound single photon emission computed tomography (SPECT) imaging studies using the α4β2 nicotinic acetylcholine receptor [123I]5-I-A85380 ligand: In vivo and in vitro evidence. Synapse, 64(2), pp. 111-116. (doi: 10.1002/syn.20705) (PMID:19771591)

Colloby, S.J., Perry, E.K., Pakrasi, S., Pimlott, S.L., Wyper, D.J., McKeith, I.G., Williams, E.D. and O'Brien, J.T. (2010) Nicotinic I-123-5IA-85380 single photon emission computed tomography as a predictor of cognitive progression in alzheimer's disease and dementia with Lewy bodies. American Journal of Geriatric Psychiatry, 18(1), pp. 86-90. (doi: 10.1097/JGP.0b013e3181b972aa)

Cavanagh, J. , Paterson, C., McLean, J., Pimlott, S. , McDonald, M., Patterson, J., Wyper, D. and McInnes, I. (2010) Tumour necrosis factor blockade mediates altered serotonin transporter availability in rheumatoid arthritis: a clinical, proof-of-concept study. Annals of the Rheumatic Diseases, 69(6), 1251-U367. (doi: 10.1136/ard.2009.107912)

Knol, R.J.J., De Bruin, K., Van Eck-Smit, B.L.F., Pimlott, S.L. , Wyper, D.J. and Booij, J. (2009) In vivo [123I]CNS-1261 binding to D-serine-activated and MK801-blocked NMDA receptors: A storage phosphor imaging study in rats. Synapse, 63(7), pp. 557-564. (doi: 10.1002/syn.20629)

Lewis, D., Champion, S. , Dewar, D. , Honey, G., Gross, J., Robichaud, A., Welch, A., Wyper, D. and Pimlott, S. (2009) Characterisation of Novel Histamine H3 receptor tracers for SPECT. Journal of Labelled Compounds and Radiopharmaceuticals, 52(S1), S381. (doi: 10.1002/jlcr.1646)

McLean, J., Brennan, D., Wyper, D.J., Condon, B., Hadley, D.M. and Cavanagh, J. (2009) Localisation of regions of intense pleasure response evoked by soccer goals. Psychiatry Research: Neuroimaging, 171(1), pp. 33-43. (doi: 10.1016/j.pscychresns.2008.02.005)

O’Brien, J. T., Colloby, S. J., Pakrasi, S., Perry, E. K., Pimlott, S. L. , Wyper, D. J., McKeith, I. G. and Williams, E. D. (2008) Nicotinic α4β2 receptor binding in dementia with Lewy bodies using 123I-5IA-85380 SPECT demonstrates a link between occipital changes and visual hallucinations. NeuroImage, 40(3), pp. 1056-1063. (doi: 10.1016/j.neuroimage.2008.01.010) (PMID:18295510))

Colloby, S.J., Pakrasi, S., Perry, E.K., Pimlott, S.L. , Wyper, D.J., Williams, E.D., McKeith, I.G. and O'Brien, J.T. (2008) The effects of donepezil on nicotinic receptor status in dementia: a ¹²³I-5IA-85380 SPECT study. Journal of Neurology, Neurosurgery and Psychiatry, 79(4), pp. 485-487. (doi: 10.1136/jnnp.2007.121780)

Pimlott, S. L. , Stevenson, L., Wyper, D. J. and Sutherland, A. (2008) Rapid and efficient radiosynthesis of [I-123]I-PK11195, a single photon emission computed tomography tracer for peripheral benzodiazepine receptors. Nuclear Medicine and Biology, 35(5), pp. 537-542. (doi: 10.1016/j.nucmedbio.2008.02.013)

Terrière, E. et al. (2008) α4β2-nicotinic receptor binding with 5-IA in Alzheimer’s disease: methods of scan analysis. Neurochemical Research, 33(4), pp. 643-651. (doi: 10.1007/s11064-007-9517-4)

O'Brien, J.T., Colloby, S.J., Pakrasi, S., Perry, E.K., Pimlott, S.L. , Wyper, D.J., McKeith, I.G. and Williams, E. (2007) Alpha4beta2 nicotinic receptor status in Alzheimer's disease using 123I-5IA-85380 single-photon-emission computed tomography. Journal of Neurology Neurosurgery and Psychiatry, 78(4), pp. 356-362. (doi: 10.1136/jnnp.2006.108209) (PMID:17135460) (PMCID:PMC2077777)

Pimlott, S. L. , Piggott, M., Patterson, J., Cavanagh, J. and Wyper, D. J. (2007) SPECT imaging of the α4β2 nicotinic receptor using [5-¹²³I]A85380. Journal of Labelled Compounds and Radiopharmaceuticals, 50(5-6), pp. 350-353. (doi: 10.1002/jlcr.1192)

Pimlott, S.L. , Piggott, M., Ballard, C., McKeith, I., Perry, R., Kometa, S., Owens, J., Wyper, D. and Perry, E. (2006) Thalamic nicotinic receptors implicated in disturbed consciousness in dementia with Lewy bodies. Neurobiology of Disease, 21(1), pp. 50-56. (doi: 10.1016/j.nbd.2005.06.008) (PMID:16023355)

Pimlott, S.L. , Piggott, M., Owens, J., Greally, E., Court, J.A., Jaros, E., Perry, R.H., Perry, E.K. and Wyper, D. (2004) Nicotinic Acetylcholine Receptor Distribution in Alzheimer's Disease, Dementia with Lewy Bodies, Parkinson's Disease, and Vascular Dementia: In Vitro Binding Study Using 5-[125I]-A-85380. Neuropsychopharmacology, 29, pp. 108-116. (doi: 10.1038/sj.npp.1300302) (PMID:12955099)

Brown, D., Chisholm, J. A., Owens, J., Pimlott, S. , Patterson, J. and Wyper, D. (2003) Acetylcholine muscarinic receptors and response to anti-cholinesterase therapy in patients with Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging, 30(2), pp. 296-300. (doi: 10.1007/s00259-002-1028-6) (PMID:12552349)

Benamer, H. T.S., Patterson, J., Wyper, D. J., Hadley, D. M., Macphee, G.J.A. and Grosset, D. G. (2000) Correlation of Parkinson's disease severity and duration with 123I-FP-CIT SPECT striatal uptake. Movement Disorders, 15(4), pp. 692-698. (doi: 10.1002/1531-8257(200007)15:4<692::AID-MDS1014>3.0.CO;2-V) (PMID:10928580)

Book Sections

Pimlott, S.L. , Owens, J. and Wyper, D. (2003) Novel SPECT receptor ligands for the investigation of dementia. In: Ebmeier, K.P. (ed.) SPECT in Dementia. Series: Advances in Biological Psychiatry, 22. S. Karger AG, pp. 95-114.

Conference or Workshop Item

O'Brien, J. T., Colloby, S. J., Pakrasi, S., Perry, E. K., Pimlott, S. L. and Wyper, D. J. (2006) Measurement of the α4β2 nicotinic receptor in vivo in Alzheimer's disease with 123I–5IA–85380 SPECT. Alzheimer's Association 10th International Conference on Alzheimer's Disease and Related Disorders, Madrid, Spain, 15-20 Jul 2006. S677. (doi: 10.1016/j.jalz.2006.05.2264)