Dr Sue Champion
- Honorary Lecturer (Undergraduate Medical School)
email:
Sue.Champion@glasgow.ac.uk
PET - RPU, West of Scotland PET centre, Tom Wheldon Building, Gartnavel General Hospital, 1053 Great Western Road, G12 0YN
Publications
2014
Morran, D. C. et al. (2014) Targeting mTOR dependency in pancreatic cancer. Gut, 63(9), pp. 1481-1489. (doi: 10.1136/gutjnl-2013-306202) (PMID:24717934) (PMCID:PMC4145424)
Lewis, D. Y., Champion, S. , Wyper, D., Dewar, D. and Pimlott, S. (2014) Assessment of [125I]WYE-230949 as a novel histamine H3 receptor radiopharmaceutical. PLoS ONE, 9(12), e115876. (doi: 10.1371/journal.pone.0115876) (PMID:25542008) (PMCID:PMC4277420)
2013
Cant, A.A., Champion, S. , Bhalla, R., Pimlott, S.L. and Sutherland, A. (2013) Nickel-mediated radioiodination of aryl and heteroaryl bromides: rapid synthesis of tracers for SPECT imaging. Angewandte Chemie (International Edition), 52(30), pp. 7829-7832. (doi: 10.1002/anie.201302800)
McCluskey, A.G., Mairs, R.J. , Sorensen, A., Robson, T., McCarthy, H.O., Pimlott, S.L. , Babich, J.W., Champion, S. and Boyd, M. (2013) Gamma irradiation and targeted radionuclides enhance the expression of the noradrenaline transporter transgene controlled by the radio-inducible p21WAF1/CIP1 promoter. Radiation Research, 179(3), pp. 282-292. (doi: 10.1667/RR3030.1)
2012
McCluskey, A.G., Mairs, R.J. , Tesson, M., Pimlott, S.L. , Babich, J.W., Gaze, M.N., Champion, S. and Boyd, M. (2012) Inhibition of poly(ADP-ribose) polymerase enhances the toxicity of 131I-metaiodobenzylguanidine/topotecan combination therapy to cells and xenografts that express the noradrenaline transporter. Journal of Nuclear Medicine, 53(7), pp. 1146-1154. (doi: 10.2967/jnumed.111.095943)
Nicol, A., Krishnadas, R. , Champion, S. , Tamagnan, G., Stehouwer, J.S., Goodman, M.M., Hadley, D. and Pimlott, S.L. (2012) Biodistribution and dosimetry of 123I-mZIENT: a novel ligand for imaging serotonin transporters. European Journal of Nuclear Medicine and Molecular Imaging, 39(5), pp. 786-791. (doi: 10.1007/s00259-011-2056-x)
McCluskey, A.G., Mairs, R.J. , Tesson, M., Pimlott, S.L. , Babich, J.W., Gaze, M.N., Champion, S. and Boyd, M. (2012) Inhibition of poly(ADP-ribose) polymerase enhances the toxicity of 131I-metaiodobenzylguanidine/topotecan combination therapy to cells and xenografts that express the noradrenaline transporter. Journal of Nuclear Medicine, 53(7), pp. 1146-1154. (doi: 10.2967/jnumed.111.095943)
2011
Champion, S. , Nicol, A., Krishnadas, R. , Kudej, G., Tamagnan, G., Stehouwer, J.S., Goodman, M.M. and Pimlott, S. (2011) Human biodistribution, dosimetry and brain SPECT imaging with [123I]-mZIENT. 19th International Symposium on Radiopharmaceutical Sciences, Amsterdam, Netherlands, 28 Aug-2 Sep 2011. S299. (doi: 10.1002/jlcr.1925)
Champion, S. , Gross, J., Robichaud, A.J. and Pimlott, S. (2011) Radiosynthesis of 123I-labelled benzimidazoles as novel single-photon emission computed tomography tracers for the histamine H3 receptor. Journal of Labelled Compounds and Radiopharmaceuticals, 54(10), pp. 674-677. (doi: 10.1002/jlcr.1899)
Krishnadas, R. , Nicol, A., Champion, S. , Pimlott, S., Stehouwer, J., Tamagnan, G., Goodman, M. and Hadley, D. (2011) Spect imaging of the serotonin transporter using a novel ligand - 123-I mZIENT - in human subjects - a dosimetry and biodisortribution study. European Psychiatry, p. 935. (doi: 10.1016/S0924-9338(11)72640-2)
2010
Lewis, D.Y., Champion, S. , Dewar, D. , Honey, G., Gross, J., Robichaud, A.J., Welch, A., Wyper, D. and Pimlott, S. (2010) Characterisation of novel histamine H3 receptor tracers for SPECT. Molecular Imaging and Biology, 12(S122), pp. 462-493.
2009
Brown, L.J. et al. (2009) Synthesis of the positron-emitting radiotracer [18F]-2-fluoro-2-deoxy-d-glucose from resin-bound perfluoroalkylsulfonates. Organic and Biomolecular Chemistry, 7(3), p. 564. (doi: 10.1039/B816032E)
Champion, S. , Lewis, D., Dewar, D. , Honey, G., Gross, J., Robichaud, A., Welch, A., Wyper, D. and Pimlott, S. (2009) Radiosynthesis and evaluation of novel histamine H3 tracers. Eighteenth International Symposium on Radiopharmaceutical Sciences, Edmonton, Canada, 12 – 17 Jul 2009. S381. (doi: 10.1002/jlcr.1646)
Lewis, D., Champion, S. , Dewar, D. , Honey, G., Gross, J., Robichaud, A., Welch, A., Wyper, D. and Pimlott, S. (2009) Characterisation of Novel Histamine H3 receptor tracers for SPECT. Journal of Labelled Compounds and Radiopharmaceuticals, 52(S1), S381. (doi: 10.1002/jlcr.1646)
2008
Glaser, M., Morrison, M., Solbakken, M., Arukwe, J., Karlsen, H., Wiggen, U., Champion, S. , Kindberg, G.M. and Cuthbertson, A. (2008) Radiosynthesis and biodistribution of cyclic RGD peptides conjugated with novel [18F] fluorinated aldehyde-containing prosthetic groups. Bioconjugate Chemistry, 19(4), pp. 951-957. (doi: 10.1021/bc700472w)
Articles
Morran, D. C. et al. (2014) Targeting mTOR dependency in pancreatic cancer. Gut, 63(9), pp. 1481-1489. (doi: 10.1136/gutjnl-2013-306202) (PMID:24717934) (PMCID:PMC4145424)
Lewis, D. Y., Champion, S. , Wyper, D., Dewar, D. and Pimlott, S. (2014) Assessment of [125I]WYE-230949 as a novel histamine H3 receptor radiopharmaceutical. PLoS ONE, 9(12), e115876. (doi: 10.1371/journal.pone.0115876) (PMID:25542008) (PMCID:PMC4277420)
Cant, A.A., Champion, S. , Bhalla, R., Pimlott, S.L. and Sutherland, A. (2013) Nickel-mediated radioiodination of aryl and heteroaryl bromides: rapid synthesis of tracers for SPECT imaging. Angewandte Chemie (International Edition), 52(30), pp. 7829-7832. (doi: 10.1002/anie.201302800)
McCluskey, A.G., Mairs, R.J. , Sorensen, A., Robson, T., McCarthy, H.O., Pimlott, S.L. , Babich, J.W., Champion, S. and Boyd, M. (2013) Gamma irradiation and targeted radionuclides enhance the expression of the noradrenaline transporter transgene controlled by the radio-inducible p21WAF1/CIP1 promoter. Radiation Research, 179(3), pp. 282-292. (doi: 10.1667/RR3030.1)
McCluskey, A.G., Mairs, R.J. , Tesson, M., Pimlott, S.L. , Babich, J.W., Gaze, M.N., Champion, S. and Boyd, M. (2012) Inhibition of poly(ADP-ribose) polymerase enhances the toxicity of 131I-metaiodobenzylguanidine/topotecan combination therapy to cells and xenografts that express the noradrenaline transporter. Journal of Nuclear Medicine, 53(7), pp. 1146-1154. (doi: 10.2967/jnumed.111.095943)
Nicol, A., Krishnadas, R. , Champion, S. , Tamagnan, G., Stehouwer, J.S., Goodman, M.M., Hadley, D. and Pimlott, S.L. (2012) Biodistribution and dosimetry of 123I-mZIENT: a novel ligand for imaging serotonin transporters. European Journal of Nuclear Medicine and Molecular Imaging, 39(5), pp. 786-791. (doi: 10.1007/s00259-011-2056-x)
McCluskey, A.G., Mairs, R.J. , Tesson, M., Pimlott, S.L. , Babich, J.W., Gaze, M.N., Champion, S. and Boyd, M. (2012) Inhibition of poly(ADP-ribose) polymerase enhances the toxicity of 131I-metaiodobenzylguanidine/topotecan combination therapy to cells and xenografts that express the noradrenaline transporter. Journal of Nuclear Medicine, 53(7), pp. 1146-1154. (doi: 10.2967/jnumed.111.095943)
Champion, S. , Gross, J., Robichaud, A.J. and Pimlott, S. (2011) Radiosynthesis of 123I-labelled benzimidazoles as novel single-photon emission computed tomography tracers for the histamine H3 receptor. Journal of Labelled Compounds and Radiopharmaceuticals, 54(10), pp. 674-677. (doi: 10.1002/jlcr.1899)
Krishnadas, R. , Nicol, A., Champion, S. , Pimlott, S., Stehouwer, J., Tamagnan, G., Goodman, M. and Hadley, D. (2011) Spect imaging of the serotonin transporter using a novel ligand - 123-I mZIENT - in human subjects - a dosimetry and biodisortribution study. European Psychiatry, p. 935. (doi: 10.1016/S0924-9338(11)72640-2)
Lewis, D.Y., Champion, S. , Dewar, D. , Honey, G., Gross, J., Robichaud, A.J., Welch, A., Wyper, D. and Pimlott, S. (2010) Characterisation of novel histamine H3 receptor tracers for SPECT. Molecular Imaging and Biology, 12(S122), pp. 462-493.
Brown, L.J. et al. (2009) Synthesis of the positron-emitting radiotracer [18F]-2-fluoro-2-deoxy-d-glucose from resin-bound perfluoroalkylsulfonates. Organic and Biomolecular Chemistry, 7(3), p. 564. (doi: 10.1039/B816032E)
Lewis, D., Champion, S. , Dewar, D. , Honey, G., Gross, J., Robichaud, A., Welch, A., Wyper, D. and Pimlott, S. (2009) Characterisation of Novel Histamine H3 receptor tracers for SPECT. Journal of Labelled Compounds and Radiopharmaceuticals, 52(S1), S381. (doi: 10.1002/jlcr.1646)
Glaser, M., Morrison, M., Solbakken, M., Arukwe, J., Karlsen, H., Wiggen, U., Champion, S. , Kindberg, G.M. and Cuthbertson, A. (2008) Radiosynthesis and biodistribution of cyclic RGD peptides conjugated with novel [18F] fluorinated aldehyde-containing prosthetic groups. Bioconjugate Chemistry, 19(4), pp. 951-957. (doi: 10.1021/bc700472w)
Conference or Workshop Item
Champion, S. , Nicol, A., Krishnadas, R. , Kudej, G., Tamagnan, G., Stehouwer, J.S., Goodman, M.M. and Pimlott, S. (2011) Human biodistribution, dosimetry and brain SPECT imaging with [123I]-mZIENT. 19th International Symposium on Radiopharmaceutical Sciences, Amsterdam, Netherlands, 28 Aug-2 Sep 2011. S299. (doi: 10.1002/jlcr.1925)
Champion, S. , Lewis, D., Dewar, D. , Honey, G., Gross, J., Robichaud, A., Welch, A., Wyper, D. and Pimlott, S. (2009) Radiosynthesis and evaluation of novel histamine H3 tracers. Eighteenth International Symposium on Radiopharmaceutical Sciences, Edmonton, Canada, 12 – 17 Jul 2009. S381. (doi: 10.1002/jlcr.1646)