Dr Helen Mactier
- Honorary Senior Research Fellow (Undergraduate Medical School)
Publications
2024
Butterworth, F. R., Boulton, R., Campbell, S., Frew, G. and MacTier, H. (2024) Can transcutaneous bilirubinometry safely be used to monitor rebound hyperbilirubinaemia after phototherapy in neonates ≥35 weeks' gestation? a prospective, comparative study. Archives of Disease in Childhood: Fetal and Neonatal Edition, 109(6), pp. 634-637. (doi: 10.1136/archdischild-2023-326145) (PMID:38604650)
Shipton, C., Aitken, J., Atkinson, S., Burchmore, R. , Hamilton, R. , MacTier, H., McGill, S., Millar, E. and Houtman, A. C. (2024) Tear proteomics in infants at risk of retinopathy of prematurity: a feasibility study. Translational Vision Science and Technology, 13(5), 1. (doi: 10.1167/tvst.13.5.1) (PMID:38691083) (PMCID:PMC11077915)
2023
Hamilton, R. et al. (2023) Impaired vision in children prenatally exposed to methadone: an observational cohort study. Eye, (doi: 10.1038/s41433-023-02644-3) (Early Online Publication)
Evans, K. et al. (2023) National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the UK. Archives of Disease in Childhood: Fetal and Neonatal Edition, (doi: 10.1136/archdischild-2023-325504) (PMID:37094919) (Early Online Publication)
Spowart, K. M., Reilly, K., Mactier, H. and Hamilton, R. (2023) Executive functioning, behavioural, emotional, and cognitive difficulties in school-aged children prenatally exposed to methadone. Frontiers in Pediatrics, 11, 1118634. (doi: 10.3389/fped.2023.1118634) (PMID:37144152) (PMCID:PMC10151701)
Ali, S. et al. (2023) Neonatal outcomes of maternal SARS-CoV-2 infection in the UK: a prospective cohort study using active surveillance. Pediatric Research, (doi: 10.1038/s41390-023-02527-z) (PMID:36899124) (PMCID:PMC10000338) (Early Online Publication)
Alyahya, W., Simpson, J., Garcia, A. L. , Mactier, H., Young, D. and Edwards, C. A. (2023) Association between early feeding patterns and neonatal outcomes in very preterm infants: a retrospective cohort study. Neonatology, 120(1), pp. 71-80. (doi: 10.1159/000527522) (PMID:36603553)
Henderson, E. M.A., Tappin, D. , Young, D., Favretto, D. and Mactier, H. (2023) Assessing maternal alcohol consumption in pregnancy: does phosphatidylethanol measured from day 5 newborn blood spot cards have any value? An observational, population-based study. Archives of Disease in Childhood, 108(1), pp. 36-41. (doi: 10.1136/archdischild-2022-324394) (PMID:36288922)
2022
Evans, K. et al. (2022) National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom. BMJ Open, 12(9), e061330. (doi: 10.1136/bmjopen-2022-061330) (PMID:36171048) (PMCID:PMC9528679)
2021
Gale, C., Quigley, M. A., Placzek, A., Knight, M., Ladhani, S., Draper, E. S., Sharkey, D., Doherty, C., Mactier, H. and Kurinczuk, J. J. (2021) The ability of the neonatal immune response to handle SARS-CoV-2 infection - authors' reply. Lancet Child and Adolescent Health, 5(3), e8. (doi: 10.1016/S2352-4642(21)00004-3) (PMID:33484657) (PMCID:PMC7825901)
Godden, C., Mullan, E., Mactier, H., Boulton, R., Shaw, M., Brunton, A., Dacombe, S. and Hamilton, R. (2021) Time to standardise neonatal pulse oximetry. Archives of Disease in Childhood: Fetal and Neonatal Edition, 106(2), pp. 224-225. (doi: 10.1136/archdischild-2020-319457) (PMID:32796058)
Gale, C., Quigley, M. A., Placzek, A., Knight, M., Ladhani, S., Draper, E. S., Sharkey, D., Doherty, C., Mactier, H. and Kurinczuk, J. J. (2021) Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance. Lancet Child and Adolescent Health, 5(2), pp. 113-121. (doi: 10.1016/S2352-4642(20)30342-4) (PMID:33181124) (PMCID:PMC7818530)
2020
Mactier, H. and Hamilton, R. (2020) Prenatal opioid exposure – increasing evidence of harm. Early Human Development, 150, 105188. (doi: 10.1016/j.earlhumdev.2020.105188) (PMID:32958331)
2019
Monnelly, V. J., Hamilton, R. , Chappell, F. M., Mactier, H. and Boardman, J. P. (2019) Childhood neurodevelopment after prescription of maintenance methadone for opioid dependency in pregnancy: a systematic review and meta-analysis. Developmental Medicine and Child Neurology, 61(7), pp. 750-760. (doi: 10.1111/dmcn.14117) (PMID:30511742) (PMCID:PMC6617808)
2018
Abernethy, C., McCall, K. E., Cooper, G., Favretto, D., Vaiano, F., Bertol, E. and Mactier, H. (2018) Determining the pattern and prevalence of alcohol consumption in pregnancy by measuring biomarkers in meconium. Archives of Disease in Childhood: Fetal and Neonatal Edition, 103(3), F216-F220. (doi: 10.1136/archdischild-2016-311686) (PMID:28676561)
Monnelly, V. J., Anblagan, D., Quigley, A., Cabez, M. B., Cooper, E. S., Mactier, H., Semple, S. I., Bastin, M. E. and Boardman, J. P. (2018) Prenatal methadone exposure is associated with altered neonatal brain development. NeuroImage: Clinical, 18, pp. 9-14. (doi: 10.1016/j.nicl.2017.12.033) (PMID:29326869) (PMCID:PMC5760461)
2017
Mactier, H. (2017) Commentary on Gibson et al. (2017): Gestational age and the severity of neonatal abstinence syndrome. Addiction, 112(4), pp. 717-718. (doi: 10.1111/add.13735) (PMID:28261981)
2016
Downie, J., MacTier, H. and Bland, R. M. (2016) Should pregnant women with unknown HIV status be offered rapid HIV testing in labour? Archives of Disease in Childhood: Fetal and Neonatal Edition, 101(1), pp. 79-84. (doi: 10.1136/archdischild-2014-307226) (PMID:26668051)
2014
MacTier, H., Shipton, D., Dryden, C. and Tappin, D. M. (2014) Reduced fetal growth in methadone-maintained pregnancies is not fully explained by smoking or socio-economic deprivation. Addiction, 109(3), pp. 482-488. (doi: 10.1111/add.12400) (PMID:24321028)
2013
Mactier, H., Bradnam, M. S. and Hamilton, R. (2013) Dark-adapted oscillatory potentials in preterm infants with and without retinopathy of prematurity. Documenta Ophthalmologica, 127(1), pp. 33-40. (doi: 10.1007/s10633-013-9373-2) (PMID:23334439)
2012
Mactier, H., McCulloch, D. L., Hamilton, R. , Galloway, P., Bradnam, M. S. , Young, D., Lavy, T., Farrell, L. and Weaver, L. T. (2012) Vitamin A supplementation improves retinal function in infants at risk of retinopathy of prematurity. Journal of Pediatrics, 160(6), 954-959.e1. (doi: 10.1016/j.jpeds.2011.12.013) (PMID:22284923)
Mactier, H., McGlone, L., Hamilton, R. and MacKinnon, J. R. (2012) Neonatal abstinence syndrome can be a problem. British Medical Journal, 344, e4200. (doi: 10.1136/bmj.e4200) (PMID:22718901)
2010
Hamilton, R. , Gonzalez, P., Dudgeon, J. and Mactier, H. (2010) Visual electrophysiological findings in CHARGE syndrome with bilateral colobomas: a case report. Documenta Ophthalmologica, 121(1), pp. 63-67. (doi: 10.1007/s10633-010-9224-3) (PMID:20213536)
Hamilton, R. , McGlone, L., MacKinnon, J.R., Russell, H.C., Bradnam, M.S. and Mactier, H. (2010) Ophthalmic, clinical and visual electrophysiological findings in children born to mothers prescribed substitute methadone in pregnancy. British Journal of Ophthalmology, 94(6), pp. 696-700. (doi: 10.1136/bjo.2009.169284) (PMID:20410537)
McGlone, L., Hamilton, R. , MacKinnon, J., Russell, H. and Mactier, H. (2010) Drug misuse in pregnancy - losing sight of the baby? Scottish Medical Journal, 55(1), pp. 52-53. (doi: 10.1258/RSMSMJ.55.1.52)
2009
Norman, J.E. et al. (2009) Progesterone for the prevention of preterm birth in twin pregnancy (STOPPIT): a randomised, double-blind, placebo-controlled study and meta-analysis. Lancet, 373(9680), pp. 2034-2040. (doi: 10.1016/S0140-6736(09)60947-8)
Dryden, C., Young, D., Hepburn, M. and MacTier, H. (2009) Maternal methadone use in pregnancy: factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources. BJOG: An International Journal of Obstetrics and Gynaecology, 116(5), pp. 665-671.
2008
Hamilton, R. , Bradnam, M. S. , Dudgeon, J. and Mactier, H. (2008) Maturation of rod function in preterm infants with and without retinopathy of prematurity. Journal of Pediatrics, 153(5), pp. 605-611. (doi: 10.1016/j.jpeds.2008.05.018) (PMID:18621392)
McGlone, L., Mactier, H., Hamilton, R. , Bradnam, M.S. , Boulton, R., Borland, W., Hepburn, M. and McCulloch, D.L. (2008) Visual evoked potentials in infants exposed to methadone in utero. Archives of Disease in Childhood, 93(9), pp. 784-786. (doi: 10.1136/adc.2007.132985) (PMID:18305073)
Mactier, H., Maroo, S., Bradnam, M. and Hamilton, R. (2008) Ocular biometry in preterm infants: implications for estimation of retinal illuminance. Investigative Ophthalmology and Visual Science, 49(1), pp. 453-457. (doi: 10.1167/iovs.07-0540) (PMID:18172125)
2005
Hamilton, R. , Dudgeon, J., Bradnam, M. S. and Mactier, H. (2005) Development of the electroretinogram between 30 and 50 weeks after conception. Early Human Development, 81(5), pp. 461-464. (doi: 10.1016/j.earlhumdev.2004.10.019) (PMID:15935923)
2000
Mactier, H., Hamilton, R. , Bradnam, M. S. , Turner, T. L. and Dudgeon, J. (2000) Contact lens electroretinography in preterm infants from 32 weeks after conception: a development in current methodology. Archives of Disease in Childhood: Fetal and Neonatal Edition, 82(3), F233-F236. (doi: 10.1136/fn.82.3.F233) (PMID:10794793) (PMCID:PMC1721095)
Articles
Butterworth, F. R., Boulton, R., Campbell, S., Frew, G. and MacTier, H. (2024) Can transcutaneous bilirubinometry safely be used to monitor rebound hyperbilirubinaemia after phototherapy in neonates ≥35 weeks' gestation? a prospective, comparative study. Archives of Disease in Childhood: Fetal and Neonatal Edition, 109(6), pp. 634-637. (doi: 10.1136/archdischild-2023-326145) (PMID:38604650)
Shipton, C., Aitken, J., Atkinson, S., Burchmore, R. , Hamilton, R. , MacTier, H., McGill, S., Millar, E. and Houtman, A. C. (2024) Tear proteomics in infants at risk of retinopathy of prematurity: a feasibility study. Translational Vision Science and Technology, 13(5), 1. (doi: 10.1167/tvst.13.5.1) (PMID:38691083) (PMCID:PMC11077915)
Hamilton, R. et al. (2023) Impaired vision in children prenatally exposed to methadone: an observational cohort study. Eye, (doi: 10.1038/s41433-023-02644-3) (Early Online Publication)
Evans, K. et al. (2023) National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the UK. Archives of Disease in Childhood: Fetal and Neonatal Edition, (doi: 10.1136/archdischild-2023-325504) (PMID:37094919) (Early Online Publication)
Spowart, K. M., Reilly, K., Mactier, H. and Hamilton, R. (2023) Executive functioning, behavioural, emotional, and cognitive difficulties in school-aged children prenatally exposed to methadone. Frontiers in Pediatrics, 11, 1118634. (doi: 10.3389/fped.2023.1118634) (PMID:37144152) (PMCID:PMC10151701)
Ali, S. et al. (2023) Neonatal outcomes of maternal SARS-CoV-2 infection in the UK: a prospective cohort study using active surveillance. Pediatric Research, (doi: 10.1038/s41390-023-02527-z) (PMID:36899124) (PMCID:PMC10000338) (Early Online Publication)
Alyahya, W., Simpson, J., Garcia, A. L. , Mactier, H., Young, D. and Edwards, C. A. (2023) Association between early feeding patterns and neonatal outcomes in very preterm infants: a retrospective cohort study. Neonatology, 120(1), pp. 71-80. (doi: 10.1159/000527522) (PMID:36603553)
Henderson, E. M.A., Tappin, D. , Young, D., Favretto, D. and Mactier, H. (2023) Assessing maternal alcohol consumption in pregnancy: does phosphatidylethanol measured from day 5 newborn blood spot cards have any value? An observational, population-based study. Archives of Disease in Childhood, 108(1), pp. 36-41. (doi: 10.1136/archdischild-2022-324394) (PMID:36288922)
Evans, K. et al. (2022) National priority setting partnership using a Delphi consensus process to develop neonatal research questions suitable for practice-changing randomised trials in the United Kingdom. BMJ Open, 12(9), e061330. (doi: 10.1136/bmjopen-2022-061330) (PMID:36171048) (PMCID:PMC9528679)
Gale, C., Quigley, M. A., Placzek, A., Knight, M., Ladhani, S., Draper, E. S., Sharkey, D., Doherty, C., Mactier, H. and Kurinczuk, J. J. (2021) The ability of the neonatal immune response to handle SARS-CoV-2 infection - authors' reply. Lancet Child and Adolescent Health, 5(3), e8. (doi: 10.1016/S2352-4642(21)00004-3) (PMID:33484657) (PMCID:PMC7825901)
Godden, C., Mullan, E., Mactier, H., Boulton, R., Shaw, M., Brunton, A., Dacombe, S. and Hamilton, R. (2021) Time to standardise neonatal pulse oximetry. Archives of Disease in Childhood: Fetal and Neonatal Edition, 106(2), pp. 224-225. (doi: 10.1136/archdischild-2020-319457) (PMID:32796058)
Gale, C., Quigley, M. A., Placzek, A., Knight, M., Ladhani, S., Draper, E. S., Sharkey, D., Doherty, C., Mactier, H. and Kurinczuk, J. J. (2021) Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance. Lancet Child and Adolescent Health, 5(2), pp. 113-121. (doi: 10.1016/S2352-4642(20)30342-4) (PMID:33181124) (PMCID:PMC7818530)
Mactier, H. and Hamilton, R. (2020) Prenatal opioid exposure – increasing evidence of harm. Early Human Development, 150, 105188. (doi: 10.1016/j.earlhumdev.2020.105188) (PMID:32958331)
Monnelly, V. J., Hamilton, R. , Chappell, F. M., Mactier, H. and Boardman, J. P. (2019) Childhood neurodevelopment after prescription of maintenance methadone for opioid dependency in pregnancy: a systematic review and meta-analysis. Developmental Medicine and Child Neurology, 61(7), pp. 750-760. (doi: 10.1111/dmcn.14117) (PMID:30511742) (PMCID:PMC6617808)
Abernethy, C., McCall, K. E., Cooper, G., Favretto, D., Vaiano, F., Bertol, E. and Mactier, H. (2018) Determining the pattern and prevalence of alcohol consumption in pregnancy by measuring biomarkers in meconium. Archives of Disease in Childhood: Fetal and Neonatal Edition, 103(3), F216-F220. (doi: 10.1136/archdischild-2016-311686) (PMID:28676561)
Monnelly, V. J., Anblagan, D., Quigley, A., Cabez, M. B., Cooper, E. S., Mactier, H., Semple, S. I., Bastin, M. E. and Boardman, J. P. (2018) Prenatal methadone exposure is associated with altered neonatal brain development. NeuroImage: Clinical, 18, pp. 9-14. (doi: 10.1016/j.nicl.2017.12.033) (PMID:29326869) (PMCID:PMC5760461)
Mactier, H. (2017) Commentary on Gibson et al. (2017): Gestational age and the severity of neonatal abstinence syndrome. Addiction, 112(4), pp. 717-718. (doi: 10.1111/add.13735) (PMID:28261981)
Downie, J., MacTier, H. and Bland, R. M. (2016) Should pregnant women with unknown HIV status be offered rapid HIV testing in labour? Archives of Disease in Childhood: Fetal and Neonatal Edition, 101(1), pp. 79-84. (doi: 10.1136/archdischild-2014-307226) (PMID:26668051)
MacTier, H., Shipton, D., Dryden, C. and Tappin, D. M. (2014) Reduced fetal growth in methadone-maintained pregnancies is not fully explained by smoking or socio-economic deprivation. Addiction, 109(3), pp. 482-488. (doi: 10.1111/add.12400) (PMID:24321028)
Mactier, H., Bradnam, M. S. and Hamilton, R. (2013) Dark-adapted oscillatory potentials in preterm infants with and without retinopathy of prematurity. Documenta Ophthalmologica, 127(1), pp. 33-40. (doi: 10.1007/s10633-013-9373-2) (PMID:23334439)
Mactier, H., McCulloch, D. L., Hamilton, R. , Galloway, P., Bradnam, M. S. , Young, D., Lavy, T., Farrell, L. and Weaver, L. T. (2012) Vitamin A supplementation improves retinal function in infants at risk of retinopathy of prematurity. Journal of Pediatrics, 160(6), 954-959.e1. (doi: 10.1016/j.jpeds.2011.12.013) (PMID:22284923)
Mactier, H., McGlone, L., Hamilton, R. and MacKinnon, J. R. (2012) Neonatal abstinence syndrome can be a problem. British Medical Journal, 344, e4200. (doi: 10.1136/bmj.e4200) (PMID:22718901)
Hamilton, R. , Gonzalez, P., Dudgeon, J. and Mactier, H. (2010) Visual electrophysiological findings in CHARGE syndrome with bilateral colobomas: a case report. Documenta Ophthalmologica, 121(1), pp. 63-67. (doi: 10.1007/s10633-010-9224-3) (PMID:20213536)
Hamilton, R. , McGlone, L., MacKinnon, J.R., Russell, H.C., Bradnam, M.S. and Mactier, H. (2010) Ophthalmic, clinical and visual electrophysiological findings in children born to mothers prescribed substitute methadone in pregnancy. British Journal of Ophthalmology, 94(6), pp. 696-700. (doi: 10.1136/bjo.2009.169284) (PMID:20410537)
McGlone, L., Hamilton, R. , MacKinnon, J., Russell, H. and Mactier, H. (2010) Drug misuse in pregnancy - losing sight of the baby? Scottish Medical Journal, 55(1), pp. 52-53. (doi: 10.1258/RSMSMJ.55.1.52)
Norman, J.E. et al. (2009) Progesterone for the prevention of preterm birth in twin pregnancy (STOPPIT): a randomised, double-blind, placebo-controlled study and meta-analysis. Lancet, 373(9680), pp. 2034-2040. (doi: 10.1016/S0140-6736(09)60947-8)
Dryden, C., Young, D., Hepburn, M. and MacTier, H. (2009) Maternal methadone use in pregnancy: factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources. BJOG: An International Journal of Obstetrics and Gynaecology, 116(5), pp. 665-671.
Hamilton, R. , Bradnam, M. S. , Dudgeon, J. and Mactier, H. (2008) Maturation of rod function in preterm infants with and without retinopathy of prematurity. Journal of Pediatrics, 153(5), pp. 605-611. (doi: 10.1016/j.jpeds.2008.05.018) (PMID:18621392)
McGlone, L., Mactier, H., Hamilton, R. , Bradnam, M.S. , Boulton, R., Borland, W., Hepburn, M. and McCulloch, D.L. (2008) Visual evoked potentials in infants exposed to methadone in utero. Archives of Disease in Childhood, 93(9), pp. 784-786. (doi: 10.1136/adc.2007.132985) (PMID:18305073)
Mactier, H., Maroo, S., Bradnam, M. and Hamilton, R. (2008) Ocular biometry in preterm infants: implications for estimation of retinal illuminance. Investigative Ophthalmology and Visual Science, 49(1), pp. 453-457. (doi: 10.1167/iovs.07-0540) (PMID:18172125)
Hamilton, R. , Dudgeon, J., Bradnam, M. S. and Mactier, H. (2005) Development of the electroretinogram between 30 and 50 weeks after conception. Early Human Development, 81(5), pp. 461-464. (doi: 10.1016/j.earlhumdev.2004.10.019) (PMID:15935923)
Mactier, H., Hamilton, R. , Bradnam, M. S. , Turner, T. L. and Dudgeon, J. (2000) Contact lens electroretinography in preterm infants from 32 weeks after conception: a development in current methodology. Archives of Disease in Childhood: Fetal and Neonatal Edition, 82(3), F233-F236. (doi: 10.1136/fn.82.3.F233) (PMID:10794793) (PMCID:PMC1721095)