Dr Kyle Cunningham
- Affiliate Researcher (School of Infection & Immunity)
https://orcid.org/0000-0002-2171-0277Publications
2025
White, S. E. et al. (2025) TGM6 is a helminth secretory product that mimics TGF-β binding to TGFBR2 to antagonize signaling in fibroblasts. Nature Communications, 16(1), 1847. (doi: 10.1038/s41467-025-56954-z) (PMID:39984487) (PMCID:PMC11845725)
2024
Singh, S. P. et al. (2024) The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding. EMBO Reports, (doi: 10.1038/s44319-024-00323-2) (Early Online Publication)
Cunningham, K. T. and Maizels, R. M. (2024) We are what we eat: macrophages and efferocytosis. Trends in Parasitology, 40(6), pp. 446-448. (doi: 10.1016/j.pt.2024.05.004) (PMID:38772757)
Kelly, C. J., Lindsay, S. L. , Smith, R. S., Keh, S., Cunningham, K. T. , Thümmler, K. , Maizels, R. M. , Campbell, J. D.M. and Barnett, S. C. (2024) Development of good manufacturing practice-compatible isolation and culture methods for human olfactory mucosa-derived mesenchymal stromal cells. International Journal of Molecular Sciences, 25(2), 743. (doi: 10.3390/ijms25020743) (PMID:38255817)
2023
Cunningham, K. T. and Mills, K. H. G. (2023) Modulation of haematopoiesis by protozoal and helminth parasites. Parasite Immunology, 45(12), e12975. (doi: 10.1111/pim.12975) (PMID:36797216) (PMCID:PMC10909493)
van Dinther, M. et al. (2023) CD44 acts as a co-receptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic. Proceedings of the National Academy of Sciences of the United States of America, 120(34), e230237012. (doi: 10.1073/pnas.2302370120) (PMID:37590410) (PMCID:PMC10450677)
2022
Mukundan, A., Byeon, C.-H., Hinck, C. S., Cunningham, K. , Campion, T., Smyth, D. J. , Maizels, R. M. and Hinck, A. P. (2022) Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-ß to its receptors, TßRI and TßRII. Journal of Biological Chemistry, 298(6), 101994. (doi: 10.1016/j.jbc.2022.101994) (PMID:35500648) (PMCID:PMC9163516)
Articles
White, S. E. et al. (2025) TGM6 is a helminth secretory product that mimics TGF-β binding to TGFBR2 to antagonize signaling in fibroblasts. Nature Communications, 16(1), 1847. (doi: 10.1038/s41467-025-56954-z) (PMID:39984487) (PMCID:PMC11845725)
Singh, S. P. et al. (2024) The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding. EMBO Reports, (doi: 10.1038/s44319-024-00323-2) (Early Online Publication)
Cunningham, K. T. and Maizels, R. M. (2024) We are what we eat: macrophages and efferocytosis. Trends in Parasitology, 40(6), pp. 446-448. (doi: 10.1016/j.pt.2024.05.004) (PMID:38772757)
Kelly, C. J., Lindsay, S. L. , Smith, R. S., Keh, S., Cunningham, K. T. , Thümmler, K. , Maizels, R. M. , Campbell, J. D.M. and Barnett, S. C. (2024) Development of good manufacturing practice-compatible isolation and culture methods for human olfactory mucosa-derived mesenchymal stromal cells. International Journal of Molecular Sciences, 25(2), 743. (doi: 10.3390/ijms25020743) (PMID:38255817)
Cunningham, K. T. and Mills, K. H. G. (2023) Modulation of haematopoiesis by protozoal and helminth parasites. Parasite Immunology, 45(12), e12975. (doi: 10.1111/pim.12975) (PMID:36797216) (PMCID:PMC10909493)
van Dinther, M. et al. (2023) CD44 acts as a co-receptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic. Proceedings of the National Academy of Sciences of the United States of America, 120(34), e230237012. (doi: 10.1073/pnas.2302370120) (PMID:37590410) (PMCID:PMC10450677)
Mukundan, A., Byeon, C.-H., Hinck, C. S., Cunningham, K. , Campion, T., Smyth, D. J. , Maizels, R. M. and Hinck, A. P. (2022) Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-ß to its receptors, TßRI and TßRII. Journal of Biological Chemistry, 298(6), 101994. (doi: 10.1016/j.jbc.2022.101994) (PMID:35500648) (PMCID:PMC9163516)