Professor William Ferrell
- Honorary Senior Research Fellow (School of Infection & Immunity)
email:
William.Ferrell@glasgow.ac.uk
Room 407 Level 4, McGregor Building, University of Glasgow, G12 8qq
Publications
2022
Huesa, C. et al. (2022) Moderate exercise protects against joint disease in a murine model of osteoarthritis. Frontiers in Physiology, 13, 1065278. (doi: 10.3389/fphys.2022.1065278) (PMID:36545287) (PMCID:PMC9760924)
2018
Hamilton, K., Dunning, L., Ferrell, W. R., Lockhart, J. C. and MacKenzie, A. (2018) Endothelium-derived contraction in a model of rheumatoid arthritis is mediated via angiotensin II type 1 receptors. Vascular Pharmacology, 100, pp. 51-57. (doi: 10.1016/j.vph.2017.11.001) (PMID:29122658)
2017
Wilkinson, D. J. et al. (2017) The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover. Scientific Reports, 7, 16693. (doi: 10.1038/s41598-017-17028-3) (PMID:29196708) (PMCID:PMC5711915)
2016
Huesa, C. et al. (2016) Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology. Annals of the Rheumatic Diseases, 75(11), pp. 1989-1997. (doi: 10.1136/annrheumdis-2015-208268) (PMID:26698846) (PMCID:PMC5099200)
Mullan, A., Delles, C. , Ferrell, W., Mullen, W. , Edwards, C. A. , McColl, J. H. , Roberts, S. A. and Lean, M. (2016) Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized trial. Atherosclerosis, 246, pp. 169-176. (doi: 10.1016/j.atherosclerosis.2016.01.004) (PMID:26797134)
2014
Sassarini, J., Krishnadas, R. , Cavanagh, J. , Nicol, A., Pimlott, S. L. , Ferrell, W. and Lumsden, M. A. (2014) Venlafaxine alters microvascular perfusion, [123I]-beta-CIT binding and BDI scores in flushing postmenopausal women. Maturitas, 77(3), pp. 267-273. (doi: 10.1016/j.maturitas.2013.12.003)
2013
MacKenzie, A., Dunning, L., Ferrell, W. R. and Lockhart, J. C. (2013) Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis. Life Sciences, 92(23), pp. 1131-1137. (doi: 10.1016/j.lfs.2013.04.011) (PMID:23643673)
Crilly, A., Palmer, H.S., Nickdel, M.B., Dunning, L., Lockhart, J.C., Plevin, R., McInnes, I.B. and Ferrell, W.R. (2013) Immunomodulatory role of proteinase-activated receptor-2. Annals of the Rheumatic Diseases, 71(9), pp. 1559-1566. (doi: 10.1136/annrheumdis-2011-200869) (PMID:22563031)
Steven, R., Crilly, A., Lockhart, J. C., Ferrell, W. R. and McInnes, I. B. (2013) Proteinase-activated receptor-2 modulates human macrophage differentiation andeffector function. Innate Immunity, 19(6), pp. 663-672. (doi: 10.1177/1753425913479984) (PMID:23606513)
2012
Tindell, A.G., Kelso, E.B., Ferrell, W.R., Lockhart, J.C., Walsh, D.A. , Dunning, L. and McInnes, I.B. (2012) Correlation of protease-activated receptor-2 expression and synovitis in rheumatoid and osteoarthritis. Rheumatology International, 32(10), pp. 3077-3086. (doi: 10.1007/s00296-011-2102-9) (PMID:21913036)
Sassarini, J., Fox, H., Ferrell, W., Sattar, N. and Lumsden, M.A. (2012) Hot flushes, vascular reactivity and the role of the α-adrenergic system. Climacteric, 15(4), pp. 332-338. (doi: 10.3109/13697137.2011.636847)
Crilly, A. et al. (2012) PAR2 expression in peripheral blood monocytes of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71(6), pp. 1049-1054. (doi: 10.1136/annrheumdis-2011-200703) (PMID:22294632)
2011
Sassarini, J., Fox, H., Ferrell, W., Sattar, N. and Lumsden, M.A. (2011) Vascular function and cardiovascular risk factors in women with severe flushing. Clinical Endocrinology, 74(1), pp. 97-103. (doi: 10.1111/j.1365-2265.2010.03921.x)
2010
Ferrell, W.R., Kelso, E.B., Lockhart, J.C., Plevin, R. and McInnes, I.B. (2010) Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis. Annals of the Rheumatic Diseases, 69(11), pp. 2051-2054. (doi: 10.1136/ard.2010.130336) (PMID:20584806)
McIntosh, K., Cunningham, M.R., Cadalbert, L., Lockhart, J., Boyd, G., Ferrell, W.R. and Plevin, R. (2010) Proteinase-activated receptor-2 mediated inhibition of TNFα-stimulated JNK activation — A novel paradigm for Gq/11 linked GPCRs. Cellular Signalling, 22(2), pp. 265-273. (doi: 10.1016/j.cellsig.2009.09.028)
Milner, J.M. et al. (2010) Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. Arthritis and Rheumatism, 62(7), pp. 1955-1966. (doi: 10.1002/art.27476)
2009
Kanagalingam, M.G., Nelson, S., Freeman, D., Ferrell, W.R., Cherry, L.M., Lowe, G.D.O., Greer, I.A. and Sattar, N.A. (2009) Vascular dysfunction and alteration of novel and classic cardiovascular risk factors in mothers of growth restricted offspring. Atherosclerosis, 205(1), pp. 244-250. (doi: 10.1016/j.atherosclerosis.2008.10.006)
Riley, S., Gibbs, T.J., Ferrell, W.R., Nelson, P.R., Smith, W.C.S. and Murphy, M.J. (2009) Getting the most out of student selected components: 12 tips for participating students. Medical Teacher, 31(10), pp. 895-902.
2008
Mackinnon, B., Deighan, C. J., Ferrell, W.R., Sattar, N. and Fox, J. G. (2008) Endothelial Function in Patients with Proteinuric Primary Glomerulonephritis. Nephron Clinical Practice, 109(1), c40-c47. (doi: 10.1159/000135632)
Riley, S. C., Ferrell, W.R., Gibbs, T. J., Murphy, M. J., Cairns, W. and Smith, S. (2008) Twelve tips for developing and sustaining a programme of student selected components. Medical Teacher, 30(4), pp. 370-376. (doi: 10.1080/01421590801965145)
2007
Gill, J.M. , Al-Mamari, A., Ferrell, W.R., Cleland, S.J., Perry, C.G., Sattar, N. , Packard, C.J. , Caslake, M.J. and Petrie, J.R. (2007) Effect of prior moderate exercise on postprandial metabolism in men with type 2 diabetes: Heterogeneity of responses. Atherosclerosis, 194(1), pp. 134-143. (doi: 10.1016/j.atherosclerosis.2006.10.007)
Kelso, E. B., Ferrell, W. R., Lockhart, J. C., Elias-Jones, I., Hembrough, T., Dunning, L., Gracie, J. A. and McInnes, I. B. (2007) Expression and proinflammatory role of proteinase-activated receptor 2 in rheumatoid synovium: Ex vivo studies using a novel proteinase-activated receptor 2 antagonist. Arthritis and Rheumatism, 56(3), pp. 765-771. (doi: 10.1002/art.22423) (PMID:17328048)
Stewart, F.M., Freeman, D.J. , Ramsay, J.E., Greer, I.A., Caslake, M. and Ferrell, W.R. (2007) Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers. Journal of Clinical Endocrinology and Metabolism, 92(3), pp. 969-975. (doi: 10.1210/jc.2006-2083)
Balmain, S., Padmanabhan, N., Ferrell, W., Morton, J. and McMurray, J. (2007) Differences in arterial compliance, microvascular function and venous capacitance between patients with heart failure and either preserved or reduced left ventricular systolic function. European Journal of Heart Failure, 9, pp. 865-871. (doi: 10.1016/j.ejheart.2007.06.003)
Baxendale, R., Ferrell, W., Kusel, M., Sturrock, R. and Tennant, N. (2007) Musculoskeletal reflex function in the joint hypermobility syndrome. Arthritis and Rheumatism, 57, pp. 1329-1333. (doi: 10.1002/art.22992)
Datta, D., Ferrell, W., Jadhav, S., Sattar, N. and Sturrock, R. (2007) Inflammatory suppression rapidly attenuates microvascular dysfunction in rheumatoid arthritis. Atherosclerosis, 192, pp. 391-395. (doi: 10.1016/j.atherosclerosis.2006.05.034)
Ferrell, W. (2007) Protease-activated receptor 2 mediates the proinflammatory effects of synovial mast cells. Arthritis and Rheumatism, 56(11), pp. 3532-3540. (doi: 10.1002/art.22936)
Ferrell, W. (2007) Strain dependence in murine models of monoarthritis. Inflammation Research, 56(12), pp. 511-514. (doi: 10.1007/s00011-007-7058-6)
Ferrell, W. (2007) The therapeutic potential of proteinase-activated receptors in arthritis. Current Opinion in Pharmacology, 7(3), pp. 334-338. (doi: 10.1016/j.coph.2007.01.002)
Ferrell, W., Gsell, W., Lockhart, J., McLean, S., Price, A. and Sturrock, R. (2007) Angiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis - In vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitis. Arthritis and Rheumatism, 56, pp. 441-447. (doi: 10.1002/art.22335)
Jadhav, S., Sattar, N., Petrie, J. , Cobbe, S. and Ferrell, W. (2007) Reproducibility and repeatability of peripheral microvascular assessment using lontophoresis in conjunction with laser doppler imaging. Journal of Cardiovascular Pharmacology, 50(3), pp. 343-349. (doi: 10.1097/FJC.0b013e3180dca094)
2006
Ferrell, W. (2006) Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation. Journal of Pharmacology and Experimental Therapeutics, 316(3), pp. 1017-1024. (doi: 10.1124/jpet.105.093807)
Gill, J. , Al-Mamari, A., Ferrell, W., Cleland, S., Sattar, N., Packard, C. , Petrie, J. and Caslake, M. (2006) Effects of a moderate exercise session on postprandial lipoproteins, apolipoproteins and lipoprotein remnants in middle-aged men. Atherosclerosis, 185(1), pp. 87-96. (doi: 10.1016/j.atherosclerosis.2005.06.009)
Jadhav, S., Ferrell, W., Greer, I., Petrie, J. , Cobbe, S. and Sattar, N. (2006) Effects of metformin on microvascular function and exercise tolerance in women with angina and normal coronary arteries - A randomized, double-blind, placebo-controlled study. Journal of the American College of Cardiology, 48(5), pp. 956-963. (doi: 10.1016/j.jacc.2006.04.088)
Jadhav, S., Ferrell, W., Petrie, J. , Scherbakova, O., Greer, I., Cobbe, S. and Sattar, N. (2006) Microvascular function, metabolic syndrome, and novel risk factor status in women with cardiac syndrome X. American Journal of Cardiology, 97(12), pp. 1727-1731. (doi: 10.1016/j.amjcard.2005.12.069)
2004
Egan, C.G., Lockhart, J.C. and Ferrell, W.R. (2004) Pathophysiology of vascular dysfunction in a rat model of chronic joint inflammation. Journal of Physiology, 557, pp. 635-643. (doi: 10.1113/jphysiol.2004.062984)
Ferrell, W. (2004) Amelioration of symptoms by enhancement of proprioception in patients with joint hypermobility syndrome. Arthritis and Rheumatism, 50(10), pp. 3323-3328. (doi: 10.1002/art.20582)
Ferrell, W. (2004) Divergent roles of nitrergic and prostanoid pathways in chronic joint inflammation. Annals of the Rheumatic Diseases, 63(12), pp. 1564-1570. (doi: 10.1136/ard.2003.017269)
Ferrell, W. (2004) Gender differences in regional cutaneous microcirculatory responses to capsaicin. Fundamental and Clinical Pharmacology, 18(2), pp. 195-200. (doi: 10.1111/j.1472-8206.2004.00218.x)
Gill, J.M.R., Al-Mamari, A., Ferrell, W.R., Cleland, S.J., Packard, C.J. , Sattar, N. , Petrie, J.R. and Caslake, M.J. (2004) Effects of prior moderate exercise on postprandial metabolism and vascular function in lean and centrally obese men. Journal of the American College of Cardiology, 44(12), pp. 2375-2382. (doi: 10.1016/j.jacc.2004.09.035)
Jadhav, S., Petrie, J. , Ferrell, W., Cobbe, S. and Sattar, N. (2004) Insulin resistance as a contributor to myocardial ischaemia independent of obstructive coronary atheroma: a role for insulin sensitisation? Heart, 90(12), pp. 1379-1383. (doi: 10.1136/hrt.2004.035170)
2003
Gill, J.M.R. , Caslake, M.J., McAllister, C., Tsofliou, F., Ferrell, W.R., Packard, C.J. and Malkova, D. (2003) Effects of short-term detraining on postprandial metabolism, endothelial function, and inflammation in endurance-trained men: Dissociation between changes in triglyceride metabolism and endothelial function. Journal of Clinical Endocrinology and Metabolism, 88(9), pp. 4328-4335. (doi: 10.1210/jc.2003-030226)
Ferrell, W. (2003) Combined inhibition of nitrergic and prostanoid pathways in J774 macrophages. Clinical and Experimental Rheumatology, 21(5), pp. 625-631.
Ferrell, W.R. et al. (2003) Essential role for proteinase-activated receptor-2 in arthritis. Journal of Clinical Investigation, 111, pp. 35-41. (doi: 10.1172/JCI200316913)
Ramsay, J., Simms, R., Ferrell, W., Crawford, L., Greer, I., Lumsden, M. and Sattar, N. (2003) Enhancement of endothelial function by pregnancy - Inadequate response in women with type 1 diabetes. Diabetes Care, 26, pp. 475-479.
2002
Egan, C.G., Lockhart, J.C., Ferrell, W.R., Day, S.M. and McLean, J.S. (2002) Pathophysiological basis of acute inflammatory hyperaemia in the rat knee: roles of cyclo-oxygenase-1 and-2. Journal of Physiology, 539, pp. 579-587. (doi: 10.1113/jphysiol.2001.013473)
Ferrell, W. (2002) Imaging inflammatory hyperaemia. Medical Imaging International, 12, pp. 11-13.
Ramsay, J., Ferrell, W., Crawford, L., Wallace, A., Greer, I. and Sattar, N. (2002) Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways. Journal of Clinical Endocrinology and Metabolism, 87, pp. 4231-4237. (doi: 10.1210/jc.2002-020311)
2001
Balint, P., Egan, C., Ferrell, W., Lockhart, J. and Sturrock, R. (2001) Metacarpophalangeal joints in rheumatoid arthritis: Laser Doppler imaging - Initial experience. Radiology, 220, pp. 257-262.
Ferrell, W. (2001) Expression of constitutive but not inducible cyclooxygenase maintains articular perfusion in the rat knee. Experimental Physiology, 86(2), pp. 191-197. (doi: 10.1113/eph8602129)
Articles
Huesa, C. et al. (2022) Moderate exercise protects against joint disease in a murine model of osteoarthritis. Frontiers in Physiology, 13, 1065278. (doi: 10.3389/fphys.2022.1065278) (PMID:36545287) (PMCID:PMC9760924)
Hamilton, K., Dunning, L., Ferrell, W. R., Lockhart, J. C. and MacKenzie, A. (2018) Endothelium-derived contraction in a model of rheumatoid arthritis is mediated via angiotensin II type 1 receptors. Vascular Pharmacology, 100, pp. 51-57. (doi: 10.1016/j.vph.2017.11.001) (PMID:29122658)
Wilkinson, D. J. et al. (2017) The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover. Scientific Reports, 7, 16693. (doi: 10.1038/s41598-017-17028-3) (PMID:29196708) (PMCID:PMC5711915)
Huesa, C. et al. (2016) Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology. Annals of the Rheumatic Diseases, 75(11), pp. 1989-1997. (doi: 10.1136/annrheumdis-2015-208268) (PMID:26698846) (PMCID:PMC5099200)
Mullan, A., Delles, C. , Ferrell, W., Mullen, W. , Edwards, C. A. , McColl, J. H. , Roberts, S. A. and Lean, M. (2016) Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized trial. Atherosclerosis, 246, pp. 169-176. (doi: 10.1016/j.atherosclerosis.2016.01.004) (PMID:26797134)
Sassarini, J., Krishnadas, R. , Cavanagh, J. , Nicol, A., Pimlott, S. L. , Ferrell, W. and Lumsden, M. A. (2014) Venlafaxine alters microvascular perfusion, [123I]-beta-CIT binding and BDI scores in flushing postmenopausal women. Maturitas, 77(3), pp. 267-273. (doi: 10.1016/j.maturitas.2013.12.003)
MacKenzie, A., Dunning, L., Ferrell, W. R. and Lockhart, J. C. (2013) Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis. Life Sciences, 92(23), pp. 1131-1137. (doi: 10.1016/j.lfs.2013.04.011) (PMID:23643673)
Crilly, A., Palmer, H.S., Nickdel, M.B., Dunning, L., Lockhart, J.C., Plevin, R., McInnes, I.B. and Ferrell, W.R. (2013) Immunomodulatory role of proteinase-activated receptor-2. Annals of the Rheumatic Diseases, 71(9), pp. 1559-1566. (doi: 10.1136/annrheumdis-2011-200869) (PMID:22563031)
Steven, R., Crilly, A., Lockhart, J. C., Ferrell, W. R. and McInnes, I. B. (2013) Proteinase-activated receptor-2 modulates human macrophage differentiation andeffector function. Innate Immunity, 19(6), pp. 663-672. (doi: 10.1177/1753425913479984) (PMID:23606513)
Tindell, A.G., Kelso, E.B., Ferrell, W.R., Lockhart, J.C., Walsh, D.A. , Dunning, L. and McInnes, I.B. (2012) Correlation of protease-activated receptor-2 expression and synovitis in rheumatoid and osteoarthritis. Rheumatology International, 32(10), pp. 3077-3086. (doi: 10.1007/s00296-011-2102-9) (PMID:21913036)
Sassarini, J., Fox, H., Ferrell, W., Sattar, N. and Lumsden, M.A. (2012) Hot flushes, vascular reactivity and the role of the α-adrenergic system. Climacteric, 15(4), pp. 332-338. (doi: 10.3109/13697137.2011.636847)
Crilly, A. et al. (2012) PAR2 expression in peripheral blood monocytes of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71(6), pp. 1049-1054. (doi: 10.1136/annrheumdis-2011-200703) (PMID:22294632)
Sassarini, J., Fox, H., Ferrell, W., Sattar, N. and Lumsden, M.A. (2011) Vascular function and cardiovascular risk factors in women with severe flushing. Clinical Endocrinology, 74(1), pp. 97-103. (doi: 10.1111/j.1365-2265.2010.03921.x)
Ferrell, W.R., Kelso, E.B., Lockhart, J.C., Plevin, R. and McInnes, I.B. (2010) Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis. Annals of the Rheumatic Diseases, 69(11), pp. 2051-2054. (doi: 10.1136/ard.2010.130336) (PMID:20584806)
McIntosh, K., Cunningham, M.R., Cadalbert, L., Lockhart, J., Boyd, G., Ferrell, W.R. and Plevin, R. (2010) Proteinase-activated receptor-2 mediated inhibition of TNFα-stimulated JNK activation — A novel paradigm for Gq/11 linked GPCRs. Cellular Signalling, 22(2), pp. 265-273. (doi: 10.1016/j.cellsig.2009.09.028)
Milner, J.M. et al. (2010) Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. Arthritis and Rheumatism, 62(7), pp. 1955-1966. (doi: 10.1002/art.27476)
Kanagalingam, M.G., Nelson, S., Freeman, D., Ferrell, W.R., Cherry, L.M., Lowe, G.D.O., Greer, I.A. and Sattar, N.A. (2009) Vascular dysfunction and alteration of novel and classic cardiovascular risk factors in mothers of growth restricted offspring. Atherosclerosis, 205(1), pp. 244-250. (doi: 10.1016/j.atherosclerosis.2008.10.006)
Riley, S., Gibbs, T.J., Ferrell, W.R., Nelson, P.R., Smith, W.C.S. and Murphy, M.J. (2009) Getting the most out of student selected components: 12 tips for participating students. Medical Teacher, 31(10), pp. 895-902.
Mackinnon, B., Deighan, C. J., Ferrell, W.R., Sattar, N. and Fox, J. G. (2008) Endothelial Function in Patients with Proteinuric Primary Glomerulonephritis. Nephron Clinical Practice, 109(1), c40-c47. (doi: 10.1159/000135632)
Riley, S. C., Ferrell, W.R., Gibbs, T. J., Murphy, M. J., Cairns, W. and Smith, S. (2008) Twelve tips for developing and sustaining a programme of student selected components. Medical Teacher, 30(4), pp. 370-376. (doi: 10.1080/01421590801965145)
Gill, J.M. , Al-Mamari, A., Ferrell, W.R., Cleland, S.J., Perry, C.G., Sattar, N. , Packard, C.J. , Caslake, M.J. and Petrie, J.R. (2007) Effect of prior moderate exercise on postprandial metabolism in men with type 2 diabetes: Heterogeneity of responses. Atherosclerosis, 194(1), pp. 134-143. (doi: 10.1016/j.atherosclerosis.2006.10.007)
Kelso, E. B., Ferrell, W. R., Lockhart, J. C., Elias-Jones, I., Hembrough, T., Dunning, L., Gracie, J. A. and McInnes, I. B. (2007) Expression and proinflammatory role of proteinase-activated receptor 2 in rheumatoid synovium: Ex vivo studies using a novel proteinase-activated receptor 2 antagonist. Arthritis and Rheumatism, 56(3), pp. 765-771. (doi: 10.1002/art.22423) (PMID:17328048)
Stewart, F.M., Freeman, D.J. , Ramsay, J.E., Greer, I.A., Caslake, M. and Ferrell, W.R. (2007) Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers. Journal of Clinical Endocrinology and Metabolism, 92(3), pp. 969-975. (doi: 10.1210/jc.2006-2083)
Balmain, S., Padmanabhan, N., Ferrell, W., Morton, J. and McMurray, J. (2007) Differences in arterial compliance, microvascular function and venous capacitance between patients with heart failure and either preserved or reduced left ventricular systolic function. European Journal of Heart Failure, 9, pp. 865-871. (doi: 10.1016/j.ejheart.2007.06.003)
Baxendale, R., Ferrell, W., Kusel, M., Sturrock, R. and Tennant, N. (2007) Musculoskeletal reflex function in the joint hypermobility syndrome. Arthritis and Rheumatism, 57, pp. 1329-1333. (doi: 10.1002/art.22992)
Datta, D., Ferrell, W., Jadhav, S., Sattar, N. and Sturrock, R. (2007) Inflammatory suppression rapidly attenuates microvascular dysfunction in rheumatoid arthritis. Atherosclerosis, 192, pp. 391-395. (doi: 10.1016/j.atherosclerosis.2006.05.034)
Ferrell, W. (2007) Protease-activated receptor 2 mediates the proinflammatory effects of synovial mast cells. Arthritis and Rheumatism, 56(11), pp. 3532-3540. (doi: 10.1002/art.22936)
Ferrell, W. (2007) Strain dependence in murine models of monoarthritis. Inflammation Research, 56(12), pp. 511-514. (doi: 10.1007/s00011-007-7058-6)
Ferrell, W. (2007) The therapeutic potential of proteinase-activated receptors in arthritis. Current Opinion in Pharmacology, 7(3), pp. 334-338. (doi: 10.1016/j.coph.2007.01.002)
Ferrell, W., Gsell, W., Lockhart, J., McLean, S., Price, A. and Sturrock, R. (2007) Angiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis - In vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitis. Arthritis and Rheumatism, 56, pp. 441-447. (doi: 10.1002/art.22335)
Jadhav, S., Sattar, N., Petrie, J. , Cobbe, S. and Ferrell, W. (2007) Reproducibility and repeatability of peripheral microvascular assessment using lontophoresis in conjunction with laser doppler imaging. Journal of Cardiovascular Pharmacology, 50(3), pp. 343-349. (doi: 10.1097/FJC.0b013e3180dca094)
Ferrell, W. (2006) Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation. Journal of Pharmacology and Experimental Therapeutics, 316(3), pp. 1017-1024. (doi: 10.1124/jpet.105.093807)
Gill, J. , Al-Mamari, A., Ferrell, W., Cleland, S., Sattar, N., Packard, C. , Petrie, J. and Caslake, M. (2006) Effects of a moderate exercise session on postprandial lipoproteins, apolipoproteins and lipoprotein remnants in middle-aged men. Atherosclerosis, 185(1), pp. 87-96. (doi: 10.1016/j.atherosclerosis.2005.06.009)
Jadhav, S., Ferrell, W., Greer, I., Petrie, J. , Cobbe, S. and Sattar, N. (2006) Effects of metformin on microvascular function and exercise tolerance in women with angina and normal coronary arteries - A randomized, double-blind, placebo-controlled study. Journal of the American College of Cardiology, 48(5), pp. 956-963. (doi: 10.1016/j.jacc.2006.04.088)
Jadhav, S., Ferrell, W., Petrie, J. , Scherbakova, O., Greer, I., Cobbe, S. and Sattar, N. (2006) Microvascular function, metabolic syndrome, and novel risk factor status in women with cardiac syndrome X. American Journal of Cardiology, 97(12), pp. 1727-1731. (doi: 10.1016/j.amjcard.2005.12.069)
Egan, C.G., Lockhart, J.C. and Ferrell, W.R. (2004) Pathophysiology of vascular dysfunction in a rat model of chronic joint inflammation. Journal of Physiology, 557, pp. 635-643. (doi: 10.1113/jphysiol.2004.062984)
Ferrell, W. (2004) Amelioration of symptoms by enhancement of proprioception in patients with joint hypermobility syndrome. Arthritis and Rheumatism, 50(10), pp. 3323-3328. (doi: 10.1002/art.20582)
Ferrell, W. (2004) Divergent roles of nitrergic and prostanoid pathways in chronic joint inflammation. Annals of the Rheumatic Diseases, 63(12), pp. 1564-1570. (doi: 10.1136/ard.2003.017269)
Ferrell, W. (2004) Gender differences in regional cutaneous microcirculatory responses to capsaicin. Fundamental and Clinical Pharmacology, 18(2), pp. 195-200. (doi: 10.1111/j.1472-8206.2004.00218.x)
Gill, J.M.R., Al-Mamari, A., Ferrell, W.R., Cleland, S.J., Packard, C.J. , Sattar, N. , Petrie, J.R. and Caslake, M.J. (2004) Effects of prior moderate exercise on postprandial metabolism and vascular function in lean and centrally obese men. Journal of the American College of Cardiology, 44(12), pp. 2375-2382. (doi: 10.1016/j.jacc.2004.09.035)
Jadhav, S., Petrie, J. , Ferrell, W., Cobbe, S. and Sattar, N. (2004) Insulin resistance as a contributor to myocardial ischaemia independent of obstructive coronary atheroma: a role for insulin sensitisation? Heart, 90(12), pp. 1379-1383. (doi: 10.1136/hrt.2004.035170)
Gill, J.M.R. , Caslake, M.J., McAllister, C., Tsofliou, F., Ferrell, W.R., Packard, C.J. and Malkova, D. (2003) Effects of short-term detraining on postprandial metabolism, endothelial function, and inflammation in endurance-trained men: Dissociation between changes in triglyceride metabolism and endothelial function. Journal of Clinical Endocrinology and Metabolism, 88(9), pp. 4328-4335. (doi: 10.1210/jc.2003-030226)
Ferrell, W. (2003) Combined inhibition of nitrergic and prostanoid pathways in J774 macrophages. Clinical and Experimental Rheumatology, 21(5), pp. 625-631.
Ferrell, W.R. et al. (2003) Essential role for proteinase-activated receptor-2 in arthritis. Journal of Clinical Investigation, 111, pp. 35-41. (doi: 10.1172/JCI200316913)
Ramsay, J., Simms, R., Ferrell, W., Crawford, L., Greer, I., Lumsden, M. and Sattar, N. (2003) Enhancement of endothelial function by pregnancy - Inadequate response in women with type 1 diabetes. Diabetes Care, 26, pp. 475-479.
Egan, C.G., Lockhart, J.C., Ferrell, W.R., Day, S.M. and McLean, J.S. (2002) Pathophysiological basis of acute inflammatory hyperaemia in the rat knee: roles of cyclo-oxygenase-1 and-2. Journal of Physiology, 539, pp. 579-587. (doi: 10.1113/jphysiol.2001.013473)
Ferrell, W. (2002) Imaging inflammatory hyperaemia. Medical Imaging International, 12, pp. 11-13.
Ramsay, J., Ferrell, W., Crawford, L., Wallace, A., Greer, I. and Sattar, N. (2002) Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways. Journal of Clinical Endocrinology and Metabolism, 87, pp. 4231-4237. (doi: 10.1210/jc.2002-020311)
Balint, P., Egan, C., Ferrell, W., Lockhart, J. and Sturrock, R. (2001) Metacarpophalangeal joints in rheumatoid arthritis: Laser Doppler imaging - Initial experience. Radiology, 220, pp. 257-262.
Ferrell, W. (2001) Expression of constitutive but not inducible cyclooxygenase maintains articular perfusion in the rat knee. Experimental Physiology, 86(2), pp. 191-197. (doi: 10.1113/eph8602129)