Professor Curtis Gemmell
- Honorary Senior Research Fellow (School of Infection & Immunity)
Publications
2019
Huang, D. B., Noviello, S. and Gemmell, C.G. (2019) Iclaprim reduces the incidence and severity of Staphylococcus aureus-induced septic arthritis in a murine model. Access Microbiology, 1(7), e000052. (doi: 10.1099/acmi.0.000052) (PMID:32974543) (PMCID:PMC7481738)
2018
Delpech, P., ALeryan, M., Jones, B., Gemmell, C. and Lang, S. (2018) An in vitro evaluation of the efficacy of tedizolid: implications for the treatment of skin and soft tissue infections. Diagnostic Microbiology and Infectious Disease, 91(1), pp. 93-97. (doi: 10.1016/j.diagmicrobio.2018.01.006) (PMID:29452993)
2017
Huang, D. B., Hawser, S., Gemmell, C. and Sahm, D. F. (2017) In vitro activity of Iclaprim against Methicillin-resistant Staphylococcus aureus nonsusceptible to Daptomycin, Linezolid, or Vancomycin: A pilot study. Canadian Journal of Infectious Diseases and Medical Microbiology, 2017, 3948626. (doi: 10.1155/2017/3948626)
2013
Smith, K., Gemmell, C.G. and Lang, S. (2013) Telavancin shows superior activity to vancomycin with multidrug-resistant Staphylococcus aureus in a range of in vitro biofilm models. European Journal of Clinical Microbiology and Infectious Diseases, 32(10), pp. 1327-1332. (doi: 10.1007/s10096-013-1883-z)
Barrett, M.P. , Gemmell, C.G. and Suckling, C.J. (2013) Minor groove binders as anti-infective agents. Pharmacology and Therapeutics, 139(1), pp. 12-23. (doi: 10.1016/j.pharmthera.2013.03.002)
2010
Smith, K., Gould, K., Ramage, G., Gemmell, C., Hinds, J. and Lang, S. (2010) Influence of Tigecycline on Expression of Virulence Factors in Biofilm-Associated Cells of Methicillin-Resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 54(1), pp. 380-387. (doi: 10.1128/AAC.00155-09)
2009
Brown, M., Gaffney, D., Gemmell, C., Oakes, E., Morris, S., Spooner, R., Jardine, A. and Geddes, C. (2009) Hemochromatosis gene mutations and treatment of anemia in patients on hemodialysis. Hemodialysis International, 13(4), pp. 460-466.
Smith, K., Perez, A., Ramage, G., Gemmell, C., Gemmell, C. and Lang, S. (2009) Comparison of biofilm-associated cell survival following in vitro exposure of meticillin-resistant Staphylococcus aureus biofilms to the antibiotics clindamycin, daptomycin, linezolid, tigecycline and vancomycin. International Journal of Antimicrobial Agents, 33(4), pp. 374-378.
2007
Al Doori, Z., Goroncy-Bermes, P., Gemmell, C. and Morrison, D. (2007) Low-level exposure of MRSA to octenidine dihydrochloride does not select for resistance. Journal of Antimicrobial Chemotherapy, 59(6), pp. 1280-1281.
Anthony, N. et al. (2007) Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. Journal of Medicinal Chemistry, 50, pp. 6116-6125. (doi: 10.1021/jm070831g)
2006
Gemmell, C. (2006) Future shape of MRSA infection and its control. Reviews in Medical Microbiology, 17, pp. 83-87.
Gemmell, C., Edwards, D., Fraise, A., Gould, F., Ridgway, G. and Warren, R. (2006) Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK. Journal of Antimicrobial Chemotherapy, 57(4), pp. 589-608.
2005
Andrews, J., Brenwald, N., Brown, D., Perry, J., King, A. and Gemmell, C. (2005) Evaluation of a 10 mu g cefoxitin disc for the detection of methicillin resistance in Staphylococcus aureus by BSAC methodology. Journal of Antimicrobial Chemotherapy, 56(3), pp. 599-600.
Culshaw, S. , Leung, B., Gracie, J., Campbell, C., Thomson, D., Gemmell, C., Liew, F. and McInnes, I. (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35, pp. 1438-1444. (doi: 10.1002/ejui.200425661) (PMID:15789357)
Smith, A., Hall, V., Thakker, B. and Gemmell, C. (2005) Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents. Journal of Antimicrobial Chemotherapy, 56, pp. 407-409. (doi: 10.1093/jac/dki206)
2003
Al Doori, Z., Morrison, D., Edwards, G. and Gemmell, C. (2003) Susceptibility of MRSA to triclosan. Journal of Antimicrobial Chemotherapy, 51(1), p. 185.
Cui, L. et al. (2003) Cell wall thickening is a common feature of vancomycin resistance in Staphylococcus aureus. Journal of Clinical Microbiology, 41, pp. 5-14. (doi: 10.1128/JCM.41.1.5-14.2003)
Rowan, N., Caldow, G., Gemmell, C. and Hunter, I. (2003) Production of diarrheal enterotoxins and other potential virulence factors by veterinary isolates of Bacillus species associated with nongastrointestinal infections. Applied and Environmental Microbiology, 69, pp. 2372-2376. (doi: 10.1128/AEM.69.4.2372-2376.2003)
2002
Gemmell, C. and Ford, C. (2002) Virulence factor expression by Gram-positive cocci exposed to subinhibitory concentrations of linezolid. Journal of Antimicrobial Chemotherapy, 50, pp. 665-672. (doi: 10.1093/jac/dkf192)
2001
Rowan, N.J., Deans, K., Anderson, J.G., Gemmell, C.G., Hunter, I.S. and Chaithong, T. (2001) Putative virulence factor expression by clinical and food isolates of Bacillus spp. after growth in reconstituted infant milk formulae. Applied and Environmental Microbiology, 67(9), pp. 3873-3881. (doi: 10.1128/AEM.67.9.3873-3881.2001) (PMID:11525980) (PMCID:PMC93104)
Aguila, A., Herrera, A. G., Morrison, D., Cosgrove, B., Perojo, A., Montesinos, I., Perez, J., Sierra, G., Gemmell, C. G. and Brock, J. H. (2001) Bacteriostatic activity of human lactoferrin against Staphylococcus aureus is a function of its iron-binding properties and is not influenced by antibiotic resistance. FEMS Immunology and Medical Microbiology, 31(2), pp. 145-152. (doi: 10.1111/j.1574-695X.2001.tb00511.x)
Gemmell, C. (2001) Susceptibility of a variety of clinical isolates to linezolid: a European inter-country comparison. Journal of Antimicrobial Chemotherapy, 48(1), pp. 47-52.
Kennedy, H.F., Gemmell, C.G., Bagg, J. , Gibson, B.E.S. and Michie, J.R. (2001) Antimicrobial susceptibility of blood culture isolates of viridans streptococci: relationship to a change in empirical antibiotic therapy in febrile neutropenia. Journal of Antimicrobial Chemotherapy, 47(5), 693 -696. (doi: 10.1093/jac/47.5.693)
Articles
Huang, D. B., Noviello, S. and Gemmell, C.G. (2019) Iclaprim reduces the incidence and severity of Staphylococcus aureus-induced septic arthritis in a murine model. Access Microbiology, 1(7), e000052. (doi: 10.1099/acmi.0.000052) (PMID:32974543) (PMCID:PMC7481738)
Delpech, P., ALeryan, M., Jones, B., Gemmell, C. and Lang, S. (2018) An in vitro evaluation of the efficacy of tedizolid: implications for the treatment of skin and soft tissue infections. Diagnostic Microbiology and Infectious Disease, 91(1), pp. 93-97. (doi: 10.1016/j.diagmicrobio.2018.01.006) (PMID:29452993)
Huang, D. B., Hawser, S., Gemmell, C. and Sahm, D. F. (2017) In vitro activity of Iclaprim against Methicillin-resistant Staphylococcus aureus nonsusceptible to Daptomycin, Linezolid, or Vancomycin: A pilot study. Canadian Journal of Infectious Diseases and Medical Microbiology, 2017, 3948626. (doi: 10.1155/2017/3948626)
Smith, K., Gemmell, C.G. and Lang, S. (2013) Telavancin shows superior activity to vancomycin with multidrug-resistant Staphylococcus aureus in a range of in vitro biofilm models. European Journal of Clinical Microbiology and Infectious Diseases, 32(10), pp. 1327-1332. (doi: 10.1007/s10096-013-1883-z)
Barrett, M.P. , Gemmell, C.G. and Suckling, C.J. (2013) Minor groove binders as anti-infective agents. Pharmacology and Therapeutics, 139(1), pp. 12-23. (doi: 10.1016/j.pharmthera.2013.03.002)
Smith, K., Gould, K., Ramage, G., Gemmell, C., Hinds, J. and Lang, S. (2010) Influence of Tigecycline on Expression of Virulence Factors in Biofilm-Associated Cells of Methicillin-Resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 54(1), pp. 380-387. (doi: 10.1128/AAC.00155-09)
Brown, M., Gaffney, D., Gemmell, C., Oakes, E., Morris, S., Spooner, R., Jardine, A. and Geddes, C. (2009) Hemochromatosis gene mutations and treatment of anemia in patients on hemodialysis. Hemodialysis International, 13(4), pp. 460-466.
Smith, K., Perez, A., Ramage, G., Gemmell, C., Gemmell, C. and Lang, S. (2009) Comparison of biofilm-associated cell survival following in vitro exposure of meticillin-resistant Staphylococcus aureus biofilms to the antibiotics clindamycin, daptomycin, linezolid, tigecycline and vancomycin. International Journal of Antimicrobial Agents, 33(4), pp. 374-378.
Al Doori, Z., Goroncy-Bermes, P., Gemmell, C. and Morrison, D. (2007) Low-level exposure of MRSA to octenidine dihydrochloride does not select for resistance. Journal of Antimicrobial Chemotherapy, 59(6), pp. 1280-1281.
Anthony, N. et al. (2007) Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. Journal of Medicinal Chemistry, 50, pp. 6116-6125. (doi: 10.1021/jm070831g)
Gemmell, C. (2006) Future shape of MRSA infection and its control. Reviews in Medical Microbiology, 17, pp. 83-87.
Gemmell, C., Edwards, D., Fraise, A., Gould, F., Ridgway, G. and Warren, R. (2006) Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK. Journal of Antimicrobial Chemotherapy, 57(4), pp. 589-608.
Andrews, J., Brenwald, N., Brown, D., Perry, J., King, A. and Gemmell, C. (2005) Evaluation of a 10 mu g cefoxitin disc for the detection of methicillin resistance in Staphylococcus aureus by BSAC methodology. Journal of Antimicrobial Chemotherapy, 56(3), pp. 599-600.
Culshaw, S. , Leung, B., Gracie, J., Campbell, C., Thomson, D., Gemmell, C., Liew, F. and McInnes, I. (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35, pp. 1438-1444. (doi: 10.1002/ejui.200425661) (PMID:15789357)
Smith, A., Hall, V., Thakker, B. and Gemmell, C. (2005) Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents. Journal of Antimicrobial Chemotherapy, 56, pp. 407-409. (doi: 10.1093/jac/dki206)
Al Doori, Z., Morrison, D., Edwards, G. and Gemmell, C. (2003) Susceptibility of MRSA to triclosan. Journal of Antimicrobial Chemotherapy, 51(1), p. 185.
Cui, L. et al. (2003) Cell wall thickening is a common feature of vancomycin resistance in Staphylococcus aureus. Journal of Clinical Microbiology, 41, pp. 5-14. (doi: 10.1128/JCM.41.1.5-14.2003)
Rowan, N., Caldow, G., Gemmell, C. and Hunter, I. (2003) Production of diarrheal enterotoxins and other potential virulence factors by veterinary isolates of Bacillus species associated with nongastrointestinal infections. Applied and Environmental Microbiology, 69, pp. 2372-2376. (doi: 10.1128/AEM.69.4.2372-2376.2003)
Gemmell, C. and Ford, C. (2002) Virulence factor expression by Gram-positive cocci exposed to subinhibitory concentrations of linezolid. Journal of Antimicrobial Chemotherapy, 50, pp. 665-672. (doi: 10.1093/jac/dkf192)
Rowan, N.J., Deans, K., Anderson, J.G., Gemmell, C.G., Hunter, I.S. and Chaithong, T. (2001) Putative virulence factor expression by clinical and food isolates of Bacillus spp. after growth in reconstituted infant milk formulae. Applied and Environmental Microbiology, 67(9), pp. 3873-3881. (doi: 10.1128/AEM.67.9.3873-3881.2001) (PMID:11525980) (PMCID:PMC93104)
Aguila, A., Herrera, A. G., Morrison, D., Cosgrove, B., Perojo, A., Montesinos, I., Perez, J., Sierra, G., Gemmell, C. G. and Brock, J. H. (2001) Bacteriostatic activity of human lactoferrin against Staphylococcus aureus is a function of its iron-binding properties and is not influenced by antibiotic resistance. FEMS Immunology and Medical Microbiology, 31(2), pp. 145-152. (doi: 10.1111/j.1574-695X.2001.tb00511.x)
Gemmell, C. (2001) Susceptibility of a variety of clinical isolates to linezolid: a European inter-country comparison. Journal of Antimicrobial Chemotherapy, 48(1), pp. 47-52.
Kennedy, H.F., Gemmell, C.G., Bagg, J. , Gibson, B.E.S. and Michie, J.R. (2001) Antimicrobial susceptibility of blood culture isolates of viridans streptococci: relationship to a change in empirical antibiotic therapy in febrile neutropenia. Journal of Antimicrobial Chemotherapy, 47(5), 693 -696. (doi: 10.1093/jac/47.5.693)