2018

Chaudhury, S. et al. (2018) Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias. Nature Communications, 9, 5280. (doi: 10.1038/s41467-018-07584-1) (PMID:30538250) (PMCID:PMC6290074)

O'Connor, C., Yalla, K., Salome, M. , Moka, H. A., Gómez Castañeda, E., Eyers, P. A. and Keeshan, K. (2018) Trib2 expression in granulocyte-monocyte progenitors drives a highly drug resistant acute myeloid leukaemia linked to elevated Bcl2. Oncotarget, 9(19), pp. 14977-14992. (doi: 10.18632/oncotarget.24525) (PMID:29599919) (PMCID:PMC5871090)

2016

O'Connor, C. et al. (2016) The presence of C/EBPα and its degradation are both required for TRIB2 mediated leukaemia. Oncogene, 35(40), pp. 5272-5281. (doi: 10.1038/onc.2016.66) (PMID:26996668)

Yalla, K., O'Connor, C., Campos, J. and Keeshan, K. (2016) TRIB2 Transformed GMP is the Myeloid Leukaemia Initiating Cell. 21st Congress Of The European Hematology Association, Copenhagen, Denmark, 9-12 June 2016.

Liang, K. L., O'Connor, C., Veiga, J. P., McCarthy, T. V. and Keeshan, K. (2016) TRIB2 regulates normal and stress-induced thymocyte proliferation. Cell Discovery, 2, 15050. (doi: 10.1038/celldisc.2015.50) (PMID:27462446) (PMCID:PMC4860960)

2015

Liang, K. L., O'Connor, C., McCarthy, T. V. and Keeshan, K. (2015) Investigation of the role of TRIB2 in normal murine hematopoiesis. Experimental Hematology, 43(9), S77. (doi: 10.1016/j.exphem.2015.06.181)

Pellicano, F., O'Connor, C. and Keeshan, K. (2015) An investigation of the leukaemia initiating cell in TRIB2 mediated AML. Experimental Hematology, 43(9), S88. (doi: 10.1016/j.exphem.2015.06.228)

O'Connor, C., Campos, J., Osinski, J. M., Gronostajski, R. M., Michie, A. and Keeshan, K. (2015) Nfix expression critically modulates early B lymphopoiesis and myelopoiesis. PLoS ONE, 10(3), e0120102. (doi: 10.1371/journal.pone.0120102) (PMID:25780920) (PMCID:PMC4363787)

2014

Lohan, F., O'Connor, C., Campos, J., Ohlsson, E., Salome, M. , Forde, C., Cahill, M., Kiely, P., Porse, B. and Keeshan, K. (2014) Targeting C/EBPalpha p42 and oncogene cooperativity in acute myeloid leukaemia. Experimental Hematology, 42(8), S42. (doi: 10.1016/j.exphem.2014.07.153)

O'Connor, C., Campos, J., Murphy, B., Hannon, M., Gronostajski, R., Michie, A. and Keeshan, K. (2014) NFIX influences stem and progenitor lineage fate. Experimental Hematology, 42(8), S54. (doi: 10.1016/j.exphem.2014.07.205)

Rishi, L. et al. (2014) Regulation of Trib2 by an E2F1-C/EBP feedback loop in AML cell proliferation. Blood, 123(15), pp. 2389-2400. (doi: 10.1182/blood-2013-07-511683) (PMID:24516045)

2013

Lohan, F. et al. (2013) Elucidation and therapeutic targeting of the molecular mechanism of TRIB2-mediated acute myeloid leukaemia. Blood, 122(21), p. 3792.

Ryan, S.M., O’Keeffe, G.W., O'Connor, C., Keeshan, K. and Nolan, Y.M. (2013) Negative regulation of TLX by IL-1β correlates with an inhibition of adult hippocampal neural precursor cell proliferation. Brain, Behavior, and Immunity, 33, pp. 7-13. (doi: 10.1016/j.bbi.2013.03.005)

Keeshan, K. , Hannon, M., Rishi, L., Hasemann, M., Frank, A.-K., Timoney, J., O'Connor, C., Cahill, M. and Porse, B. (2013) E2F1 positively regulates Trib2 pseudokinase expression and proliferation in acute leukaemia. Experimental Hematology, 41(8), S50. (doi: 10.1016/j.exphem.2013.05.197)

Keeshan, K. , O'Connor, C., Campos, J., Murphy, B., Hannon, M. and Michie, A. (2013) NFIX expression critically modulates early B lymphopoiesis and myelopoiesis. Experimental Hematology, 41(8), S68. (doi: 10.1016/j.exphem.2013.05.267)

Articles

Chaudhury, S. et al. (2018) Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias. Nature Communications, 9, 5280. (doi: 10.1038/s41467-018-07584-1) (PMID:30538250) (PMCID:PMC6290074)

O'Connor, C., Yalla, K., Salome, M. , Moka, H. A., Gómez Castañeda, E., Eyers, P. A. and Keeshan, K. (2018) Trib2 expression in granulocyte-monocyte progenitors drives a highly drug resistant acute myeloid leukaemia linked to elevated Bcl2. Oncotarget, 9(19), pp. 14977-14992. (doi: 10.18632/oncotarget.24525) (PMID:29599919) (PMCID:PMC5871090)

O'Connor, C. et al. (2016) The presence of C/EBPα and its degradation are both required for TRIB2 mediated leukaemia. Oncogene, 35(40), pp. 5272-5281. (doi: 10.1038/onc.2016.66) (PMID:26996668)

Liang, K. L., O'Connor, C., Veiga, J. P., McCarthy, T. V. and Keeshan, K. (2016) TRIB2 regulates normal and stress-induced thymocyte proliferation. Cell Discovery, 2, 15050. (doi: 10.1038/celldisc.2015.50) (PMID:27462446) (PMCID:PMC4860960)

Liang, K. L., O'Connor, C., McCarthy, T. V. and Keeshan, K. (2015) Investigation of the role of TRIB2 in normal murine hematopoiesis. Experimental Hematology, 43(9), S77. (doi: 10.1016/j.exphem.2015.06.181)

Pellicano, F., O'Connor, C. and Keeshan, K. (2015) An investigation of the leukaemia initiating cell in TRIB2 mediated AML. Experimental Hematology, 43(9), S88. (doi: 10.1016/j.exphem.2015.06.228)

O'Connor, C., Campos, J., Osinski, J. M., Gronostajski, R. M., Michie, A. and Keeshan, K. (2015) Nfix expression critically modulates early B lymphopoiesis and myelopoiesis. PLoS ONE, 10(3), e0120102. (doi: 10.1371/journal.pone.0120102) (PMID:25780920) (PMCID:PMC4363787)

Lohan, F., O'Connor, C., Campos, J., Ohlsson, E., Salome, M. , Forde, C., Cahill, M., Kiely, P., Porse, B. and Keeshan, K. (2014) Targeting C/EBPalpha p42 and oncogene cooperativity in acute myeloid leukaemia. Experimental Hematology, 42(8), S42. (doi: 10.1016/j.exphem.2014.07.153)

O'Connor, C., Campos, J., Murphy, B., Hannon, M., Gronostajski, R., Michie, A. and Keeshan, K. (2014) NFIX influences stem and progenitor lineage fate. Experimental Hematology, 42(8), S54. (doi: 10.1016/j.exphem.2014.07.205)

Rishi, L. et al. (2014) Regulation of Trib2 by an E2F1-C/EBP feedback loop in AML cell proliferation. Blood, 123(15), pp. 2389-2400. (doi: 10.1182/blood-2013-07-511683) (PMID:24516045)

Lohan, F. et al. (2013) Elucidation and therapeutic targeting of the molecular mechanism of TRIB2-mediated acute myeloid leukaemia. Blood, 122(21), p. 3792.

Ryan, S.M., O’Keeffe, G.W., O'Connor, C., Keeshan, K. and Nolan, Y.M. (2013) Negative regulation of TLX by IL-1β correlates with an inhibition of adult hippocampal neural precursor cell proliferation. Brain, Behavior, and Immunity, 33, pp. 7-13. (doi: 10.1016/j.bbi.2013.03.005)

Keeshan, K. , Hannon, M., Rishi, L., Hasemann, M., Frank, A.-K., Timoney, J., O'Connor, C., Cahill, M. and Porse, B. (2013) E2F1 positively regulates Trib2 pseudokinase expression and proliferation in acute leukaemia. Experimental Hematology, 41(8), S50. (doi: 10.1016/j.exphem.2013.05.197)

Keeshan, K. , O'Connor, C., Campos, J., Murphy, B., Hannon, M. and Michie, A. (2013) NFIX expression critically modulates early B lymphopoiesis and myelopoiesis. Experimental Hematology, 41(8), S68. (doi: 10.1016/j.exphem.2013.05.267)

Conference or Workshop Item

Yalla, K., O'Connor, C., Campos, J. and Keeshan, K. (2016) TRIB2 Transformed GMP is the Myeloid Leukaemia Initiating Cell. 21st Congress Of The European Hematology Association, Copenhagen, Denmark, 9-12 June 2016.