Dr Helen Mulvana

Reader in Biomedical Engineering (Biomedical Engineering)
Research Collaboration Lead (Information Services)
Affiliate (School of Engineering)

email: Helen.Mulvana@glasgow.ac.uk
pronouns: She/her/hers

Room 522, School of Engineering, James Watt South Building

Biography

Dr Helen Mulvana graduated with a degree in Product Design Engineering from the University of Glasgow and Glasgow School of Art in 2001 and obtained her EngD in Medical Devices from the University of Strathclyde in 2009. She worked as a Mechanical Design and Development Engineering for Renishaw plc and as a Project Leader for TWI Ltd prior to undertaking her post-doctoral training at Imperial College London.

Helen began her independent academic career at the University of Glasgow as a Lord Kelvin Adam Smith Fellow in 2012, followed by a Lectureship. In 2019 she secured a Senior Lectureship and Chancellor’s Fellowship in Biomedical Engineering at the University of Strathclyde in 2019, also serving as Director of Research and Deputy Head of Department. She returned to the University of Glasgow as a Reader in Biomedical Engineering in 2024.

Helen holds Chartership through the Institute of Mechanical Engineers and is currently the Vice President Medical Ultrasonics for the IEEE Ultrasonics Ferroelectrics and Frequency Control Society.

Research interests

Dr Mulvana’s research aims to improve the prospects for individuals facing cancer, something which will affect one in two of us over the course of our lifetime. She develops ultrasound technologies to pioneer novel, non-invasive tools for disease detection and treatment.

Her particular areas of expertise are in the use of ultrasound for therapeutic purposes to deliver non-invasive disease treatments, and in the development of micro and nanoscale ultrasound responsive particles that can enhance ultrasound therapies, or reveal otherwise hidden information about tissue physiology and local microstructure during ultrasound imaging. The aim is to improve sensitivity of disease detection for earlier diagnoses, non-invasive staging and reduced reliance on painful tissue biopsy, and to develop point of care treatments that can accelerate recovery.

Publications

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Jump to: 2023 | 2022 | 2021 | 2020 | 2018 | 2017 | 2015 | 2013 | 2012 | 2011 | 2010 | 2009 | 2007 | 2006

Number of items: 40.

2023

Asciak, L., Gilmour, L., Anthony Williams, J., Foster, E., Díaz-García, L., McCormick, C., Windmill, J., Mulvana, H. E. , Jackson-Camargo, J. C. and Domingo-Roca, R. (2023) Investigating multi-material hydrogel three-dimensional printing for in vitro representation of the neo-vasculature of solid tumours: a comprehensive mechanical analysis and assessment of nitric oxide release from human umbilical vein endothelial cells. Royal Society Open Science, 10(8), 230929. (doi: 10.1098/rsos.230929) (PMID:37593713) (PMCID:PMC10427827)

Adam, G., Denisov, V., Rattray, Z., Thomson, A., Moug, S., Jansson, T., Farrington, S., Moran, C. and Mulvana, H. (2023) Characterisation of multimodal contrast agents for lymph node imaging. Leeds Microbubble Symposium 2023: From Fundamentals to Application, Leeds, UK, 17-19 Jul 2023.

Adam, G., Densiov, V., Rattray, Z., Thomson, A., Moug, S., Jansson, T., Farrington, S., Moran, C. M. and Mulvana, H. (2023) Characterisation of multimodal contrast agents for Contrast Enhanced Magnetomotive Ultrasound to stage colorectal cancer. SINAPSE 15th Annual Scientific Meeting, Glasgow, UK, 14 Jun 2023.

Adam, G., Densiov, V., Rattray, Z., Thomson, A., Jansson, T., Moug, S., Farrington, S., Moran, C. and Mulvana, H. (2023) Optical and acoustic characterisation of multimodal contrast agents for colorectal cancer lymph node detection. 18th annual meeting of the European Society for Molecular Imaging, Salzburg, Austria, 14-17 Mar 2023.

2022

Sjöstrand, S. et al. (2022) Contrast enhanced magneto-motive ultrasound in lymph nodes - modelling and pre-clinical imaging using magnetic microbubbles. In: 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Glasgow, UK, 11-15 Jul 2022, pp. 194-197. ISBN 9781728127828 (doi: 10.1109/embc48229.2022.9871876)

Domingo-Roca, R., Gilmour, L., Dobre, O. , Sarrigiannidis, S., Sandison, M. E., O'Leary, R. and Mulvana, H. E. (2022) 3D printing of noncytotoxic high-resolution microchannels in Bisphenol-a ethoxylate dimethacrylate tissue-mimicking materials. 3D Printing and Additive Manufacturing, 10(5), pp. 1101-1109. (doi: 10.1089/3dp.2021.0235) (PMID:37886413)

Domingo-Roca, R., Gilmour, L., Asciak, L., Sarrigiannidis, S., Dobre, O. , Salmeron-Sanchez, M. , Sandison, M., O'Leary, R., Jackson-Camargo, J. and Mulvana, H. (2022) 3D-printed High-resolution Microchannels for Contrast Enhanced Ultrasound Research. In: 2021 IEEE International Ultrasonics Symposium (IUS), Xi'an, China, 11-16 Sep2021, ISBN 9781665403559 (doi: 10.1109/ius52206.2021.9763442)

Domingo-Roca, R., Asciak, L., Windmill, J., Mulvana, H. and Jackson-Camargo, J.C. (2022) Non-destructive analysis of the mechanical properties of 3D-printed materials. Journal of Nondestructive Evaluation, 41, 22. (doi: 10.1007/s10921-022-00854-5) (PMID:35221413) (PMCID:PMC8854310)

Bacou, M. et al. (2022) Development of preclinical ultrasound imaging techniques to identify and image sentinel lymph nodes in a cancerous animal model. Cancers, 14(3), 561. (doi: 10.3390/cancers14030561) (PMID:35158829) (PMCID:PMC8833694)

2021

Cebula, C., Nicoll Baines, K., Lido, C. , Thijssen, J. H.J., Halliday, K., Hedge, N. , Mulvana, H. and Gauchotte-Lindsay, C. (2021) Inclusion in the time of COVID: 14 ways to seize the moment for change. Nature Index, 9 Feb.

2020

Gauchotte-Lindsay, C. , Nicoll Baines, K., Cebula, C., Mulvana, H. , Lido, C. and Hedge, N. (2020) Mrs0479 - Unequal impact: Coronavirus (Covid-19) and the impact on people with protected characteristics. Documentation. UK Parliament.

2018

Domingo-Roca, R., Jackson, J.C. and Mulvana, H. (2018) Exploitation of Microbubble – Microvessel Interactions to Predict and Personalize UmTDD. Computational and Mathematical Biology Seminar, Barcelona, Spain, 18 Dec 2018. (Unpublished)

Domingo-Roca, R., Jackson, J.C. and Mulvana, H. (2018) Microbubble – Microvessel Interactions and their Influence on UmTDD: Simulation Study. 24th European Symposium on Ultrasound Contrast Imaging, Rotterdam, The Netherlands, 17-18 Jan 2019.

Domingo-Roca, R., Jackson, J. C. and Mulvana, H. (2018) Development of an Experimental Platform for Rapid Prototyping of UmTDD Methods. Ultrasound 2018, Manchester, UK, 04-06 Dec 2018.

Domingo-Roca, R., Jackson, J.C. and Mulvana, H. (2018) The Importance of Bubble-wall Interaction for Physiologically Relevant Simulations of Ultrasound-mediated Targeted Drug Delivery. IGT Network Meeting, Dundee, UK, 01 Nov 2018.

Stewart, F., Mulvana, H. , Näthke, I. and Cochran, S. (2018) Theranostics in the gut. In: Thanou, M. (ed.) Theranostics and Image Guided Drug Delivery. Series: RSC drug discovery series (63). Royal Society of Chemistry: London, pp. 182-210. ISBN 9781782624660 (doi: 10.1039/9781788010597-00182)

2017

Cochran, S. , Button, T.W., Cox, B.F., Cumming, D.R.S. , Gourevich, D., Lay, H.S. , Mulvana, H. , Nathke, I.S. and Stewart, F. (2017) Nanotechnology in Multimodal Theranostic Capsule Endoscopy. In: IEEE 17th International Conference on Nanotechnology (IEEE-NANO), Pittsburgh, PA, USA, 25-28 July 2017, pp. 434-435. ISBN 9781509030286 (doi: 10.1109/NANO.2017.8117439)

Mulvana, H. , Browning, R. J., Luan, Y., de Jong, N., Tang, M.-X., Eckersley, R. J. and Stride, E. (2017) Characterization of contrast agent microbubbles for ultrasound imaging and therapy research. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 64(1), pp. 232-251. (doi: 10.1109/TUFFC.2016.2613991) (PMID:27810805)

Stride, E., Mulvana, H. , Rademeyer, P., Carugo, D., Owen, J., Browning, R., Tang, M. and Eckersley, R. (2017) Characterisation of functionalised microbubbles for ultrasound imaging and therapy. In: Tsuji, K. (ed.) The Micro-World Observed by Ultra High-Speed Cameras. Springer: Cham, pp. 375-389. ISBN 9783319614908 (doi: 10.1007/978-3-319-61491-5_18)

2015

Foster, J. S. et al. (2015) Gelation landscape engineering using a multi-reaction supramolecular hydrogelator system. Journal of the American Chemical Society, 137(45), pp. 14236-14239. (doi: 10.1021/jacs.5b06988) (PMID:26502267) (PMCID:PMC4655419)

Gourevich, D., Volovick, A., Dogadkin, O., Wang, L., Mulvana, H. , Medan, Y., Melzer, A. and Cochran, S. (2015) In vitro investigation of the individual contributions of ultrasound-induced stable and inertial cavitation in targeted drug delivery. Ultrasound in Medicine and Biology, 41(7), pp. 1853-1864. (doi: 10.1016/j.ultrasmedbio.2015.03.016) (PMID:25887690)

2013

Mulvana, H. , Cochran, S. and Hill, M. (2013) Ultrasound assisted particle and cell manipulation on-chip. Advanced Drug Delivery Reviews, 65(11-12), pp. 1600-1610. (doi: 10.1016/j.addr.2013.07.016)

Casey, J., Sennoga, C., Mulvana, H. , Hajnal, J.V., Tang, M.-X. and Eckersley, R.J. (2013) Single bubble acoustic characterization and stability measurement of adherent microbubbles. Ultrasound in Medicine and Biology, 39(5), pp. 903-914. (doi: 10.1016/j.ultrasmedbio.2012.12.007)

2012

Mulvana, H. , Browning, R.J., Tang, M.-X., Hajnal, J.V. and Eckersley, R.J. (2012) Albumin coated microbubble optimization: custom fabrication and comprehensive characterization. Ultrasound in Medicine and Biology, 38(9), pp. 1599-1607. (doi: 10.1016/j.ultrasmedbio.2012.05.002)

Browning, R.J., Mulvana, H. , Tang, M.-X., Hajnal, J.V., Wells, D.J. and Eckersley, R.J. (2012) Effect of albumin and dextrose concentration on ultrasound and microbubble mediated gene transfection in vivo. Ultrasound in Medicine and Biology, 38(6), pp. 1067-1077. (doi: 10.1016/j.ultrasmedbio.2012.02.020)

Mulvana, H. , Stride, E., Tang, M.-X., Hajnal, J.V. and Eckersley, R.J. (2012) The influence of gas saturation on microbubble stability. Ultrasound in Medicine and Biology, 38(6), pp. 1097-1100. (doi: 10.1016/j.ultrasmedbio.2012.02.008)

Mulvana, H. , Eckersley, R.J., Tang, M.-X., Pankhurst, Q. and Stride, E. (2012) Theoretical and experimental characterisation of magnetic microbubbles. Ultrasound in Medicine and Biology, 38(5), pp. 864-875. (doi: 10.1016/j.ultrasmedbio.2012.01.027)

2011

Browning, R.J., Mulvana, H. , Tang, M., Hajnal, J.V., Wells, D.J. and Eckersley, R.J. (2011) Influence of needle gauge on in vivo ultrasound and microbubble-mediated gene transfection. Ultrasound in Medicine and Biology, 37(9), pp. 1531-1537. (doi: 10.1016/j.ultrasmedbio.2011.05.019)

Mulvana, H. , Stride, E., Tang, M., Hajnal, J.V. and Eckersley, R. (2011) Temperature-dependent differences in the nonlinear acoustic behavior of ultrasound contrast agents revealed by high-speed imaging and bulk acoustics. Ultrasound in Medicine and Biology, 37(9), pp. 1509-1517. (doi: 10.1016/j.ultrasmedbio.2011.05.020)

Tang, M.-X., Mulvana, H. , Gauthier, T., Lim, A.K.P., Cosgrove, D.O., Eckersley, R.J. and Stride, E. (2011) Quantitative contrast-enhanced ultrasound imaging: a review of sources of variability. Interface Focus, 1(4), pp. 520-539. (doi: 10.1098/rsfs.2011.0026) (PMID:22866229) (PMCID:PMC3262271)

Stride, E., Mulvana, H. , Eckersley, R.J., Tang, M.-X. and Pankhurst, Q. (2011) Magnetic microbubbles. In: Thanh, N.T.K. (ed.) Magnetic Nanoparticles: From Fabriation to Clinical Applications. CRC Press: Boca Raton, FL. ISBN 9781439869321

2010

Mulvana, H. , Stride, E., Hajnal, J.V. and Eckersley, R.J. (2010) Temperature dependent behavior of ultrasound contrast agents. Ultrasound in Medicine and Biology, 36(6), pp. 925-934. (doi: 10.1016/j.ultrasmedbio.2010.03.003)

Mulvana, H. , Eckersley, R.J., Browning, R., Hajnal, J.V., Stride, E., Barrack, T., Tang, M., Pankhurst, Q. and Wells, D. (2010) Enhanced Gene Transfection in vivo using Magnetic Localisation of Ultrasound Contrast Agents: Preliminary Results. In: IEEE International Ultrasonics Symposium 2010, San Diego, 11-14 Oct 2010, pp. 670-673. (doi: 10.1109/ULTSYM.2010.5935952)

2009

Mulvana, H. , Eckersley, R.J. and Stride, E. (2009) Temperature behaviour of ultrasound contrast agents. In: IEEE International Ultrasonics Symposium, Rome, Italy, 20-23 Sept 2009, pp. 1239-1242. (doi: 10.1109/ULTSYM.2009.5441522)

2007

Wallace, M.F., Marin, P., Mulvana, H. , Walsh, M.P., Button, T.W., Hughes, H., MacLennan, D. and Cochran, S. (2007) Applications of New Piezoelectric Materials for High Performance Ultrasonic NDT Transducers. 46th Annual British Conference on Non-Destructive Testing (2007 NDT), Glasgow, UK, 18-20 Sep 2007.

Wallace, M.F., Mulvana, H. , Marin, P., Mayne, K., Walsh, M.P., Wright, R., Marsh, R., Spence, B., Solomonidis, S. and Cochran, S. (2007) Parametric Array Design and Characterisation for Underwater Sonar and Medical Strain Imaging Applications. In: 2007 IEEE International Ultrasonics Symposium (IUS), New York, NY, USA, 28-31 Oct 2007, pp. 305-308. ISBN 9781424413836 (doi: 10.1109/ULTSYM.2007.87)

2006

Mulvana, H. , Parker, M., Saillant, J.-F. and Cochran, S. (2006) Focused Acoustic Radiation Devices for Therapeutic Ultrasound. 2nd Meeting of the UK Therapeutic Ultrasound Group, London, UK, Nov 2006.

Mulvana, H. , Cochran, S. , Spence, B., Solomonidis, S. and Mariel, A. (2006) Non-contact Focused Acoustic Radiation Force Technique for the Biomechanical Characterisation of an Amputee’s Residual Limb. Fifth International Conference on the Ultrasonic Measurement and Imaging of Tissue Elasticity (Tissue Elasticity 2006), Snowbird, UT, USA, 08-11 Oct 2006.

Cochran, S. , Marin-Franch, P., Parker, M., Mulvana, H. and Kirk, K.J. (2006) Ultrasonic Transducers for High Power Applications. Ultrasound in the Processing of Industrial Soft Solids, Leeds, UK, 09-10 Feb 2006.

Mulvana, H. , Parker, M.F., Cochran, S. , Spence, B. and Solomonidis, S. (2006) Technique for Automatic Characterisation of an Amputee's Residual Limb. In: IEEE International Ultrasonics Symposium 2006, Vancouver, Canada, 3-6 Oct 2006, pp. 2088-2091. ISBN 9781424402014 (doi: 10.1109/ULTSYM.2006.500)

This list was generated on Thu Nov 21 01:50:00 2024 GMT.

Jump to: Articles | Book Sections | Research Reports or Papers | Conference or Workshop Item | Conference Proceedings

Number of items: 40.

Articles

Mulvana, H. , Cochran, S. and Hill, M. (2013) Ultrasound assisted particle and cell manipulation on-chip. Advanced Drug Delivery Reviews, 65(11-12), pp. 1600-1610. (doi: 10.1016/j.addr.2013.07.016)

Book Sections

Research Reports or Papers

Conference or Workshop Item

Domingo-Roca, R., Jackson, J. C. and Mulvana, H. (2018) Development of an Experimental Platform for Rapid Prototyping of UmTDD Methods. Ultrasound 2018, Manchester, UK, 04-06 Dec 2018.

Conference Proceedings

This list was generated on Thu Nov 21 01:50:00 2024 GMT.

Grants

L Fruk, H Mulvana, C Alexander, S Rosser, SonoBacter: Ultrasound-Guided Activation and Imaging of Engineered Bacteria for Stroma Reprogramming, MRC, co-I

H Mulvana, S Moug, S Farrington, C Moran, T Jansson, Development of non-ionising and non-invasive, personalised colorectal cancer staging using novel multimodal contrast agents and magnetomotive ultrasound imaging, Cancer Research UK, PI

H Mulvana, J Jackson, M Sandison, R O’Leary, Transformative Anatomically accurate Microvascular flow Phantoms for Ultrasound Therapy research (TAMP-US), BBSRC, PI

J Morrison, H Mulvana, C Gauchotte Lindsey, VisNET: Virtual in situ networking to reinvent the rules of international collaborations and reduce gender differences in academic careers, EPSRC, co-Programme Director

S Taylor (including H Mulvana), Inclusion Really Does Matter: Improving Reactions to Gender Equality Initiatives Amongst Academics in Engineering and Physical Sciences, EPSRC, co-I

H Mulvana, VisNET Collaboration Social Dinner, Royal Society of Chemistry, PI (£2,903)

H Mulvana, J Jackson, Physiologically and anatomically accurate flow phantom for controlled investigation of ultrasound and microbubble mediated targeted drug delivery, Carnegie Trust, PI

S Moug, H Mulvana, Contrast enhanced ultrasound (CEUS) to advance individual staging and treatment planning in rectal cancer, Bowel and Cancer Research, co-PI

H Mulvana, Microscope based flow phantom for controlled investigation of ultrasound and microbubble targeted drug delivery, Royal Society, PI

H Mulvana, G Lloyd, Custom Bubbles, Royal Society of Edinburgh, PI

Supervision

If you are interested in PhD research on topics related to my work please contact me.

Current PhD students under my supervision

Rachel Williams (EPSRC CDT in Future Ultrasound for Science and Engineering)

Laura Merida (EPSRC CDT in Prosthetics & Orthotics)

Paveekorn Supteranon (EPSRC DTA)

Ben Hicks (EPSRC CDT in Prosthetics & Orthotics)

Andrea Orthodoxou (EPSRC CDT in Future Ultrasound for Science and Engineering)

Patricia Foia (Medical Research Scotland & NPL Ltd)

Lauren Gilmour (EPSRC DTA)

Second or co-supervision

Leah Douglas (EPSRC CDT in Future Ultrasound for Science and Engineering)

Muhammed-Rashid (EPSRC CDT in Future Ultrasound for Science and Engineering)

Pratibha (MRC DTP, University of Edinburgh)

Douglas, Leah
Nanobubbles for Earlier Pancreatic Cancer Detection
Supteranon, Paveekorn
Establishing the theranostic parameter space of phase-change nanodroplet contrast agents

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