Mr John Cole

Shared Research Facilities – Molecular Analysis Technical Lead (MVLS Research Facilities)

telephone: 0141 330 6267
email: John.Cole@glasgow.ac.uk

Publications

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Jump to: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2017 | 2016 | 2015 | 2014 | 2010

Number of items: 41.

2024

Asghar, S., Litherland, G. J., Cole, J. J., McInnes, I. B. , Meek, R.M.D., Lockhart, J. C., Goodyear, C. S. and Crilly, A. (2024) Small extracellular vesicles derived from synovial fibroblasts contain distinct miRNA profiles and contribute to chondrocyte damage in osteoarthritis. Arthritis Research and Therapy, 26(1), 167. (doi: 10.1186/s13075-024-03398-3) (PMID:39342381)

Li, X., Cole, J., Vaughan, D. , Xiao, Y., Walker, D. and Wall, D. M. (2024) Stratifying macrophages based on their infectious burden identifies novel host targets for intervention during Crohn’s disease associated adherent-invasive Escherichia coli infection. Microbiology, 170(6), 001470. (doi: 10.1099/mic.0.001470) (PMID:38916198)

Ramirez-Guzman, L. A., Huang, W., Cole, J. J. and Jorgensen, H. G. (2024) GAS2 upregulation is a targetable vulnerability in chronic myeloid leukaemia. International Journal of Translational Medicine, 4(2), pp. 354-368. (doi: 10.3390/ijtm4020023)

Nair, R., Lannagan, T. R.M., Jackstadt, R., Andrusaite, A., Cole, J., Boyne, C., Nibbs, R. J.B. , Sansom, O. J. and Milling, S. (2024) Co-inhibition of TGF-β and PD-L1 pathways in a metastatic colorectal cancer mouse model triggers interferon responses, innate cells and T cells, alongside metabolic changes and tumor resistance. OncoImmunology, 13(1), 2330194. (doi: 10.1080/2162402X.2024.2330194)

2023

Jaffery, H. et al. (2023) IĸB Protein BCL3 as a controller of osteogenesis and bone health. Arthritis and Rheumatology, 75(12), 2148-2160-2148-2160. (doi: 10.1002/art.42639) (PMID:37410754)

Thümmler, K. et al. (2023) Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis? Neuropathology and Applied Neurobiology, 49(5), e12935. (doi: 10.1111/nan.12935) (PMID:37705188)

Cole, S. et al. (2023) Differential regulation of IL-17A and IL-17F via STAT5 contributes to psoriatic disease. Journal of Allergy and Clinical Immunology, 152(3), pp. 783-798. (doi: 10.1016/j.jaci.2023.03.035) (PMID:37244461)

Ormsby, M. J. et al. (2023) An intact S-layer is advantageous to Clostridioides difficile within the host. PLoS Pathogens, 19(6), e1011015. (doi: 10.1371/journal.ppat.1011015) (PMID:37384772) (PMCID:PMC10310040)

Johnsson, H., Cole, J., McInnes, I. B. , Graham, G. and Siebert, S. (2023) Differences in transcriptional changes in psoriasis and psoriatic arthritis skin with immunoglobulin gene enrichment in psoriatic arthritis. Rheumatology, (doi: 10.1093/rheumatology/kead195) (PMID:37137278) (Early Online Publication)

Johnsson, H., Cole, J., Siebert, S. , McInnes, I. B. and Graham, G. (2023) Cutaneous lesions in psoriatic arthritis are enriched in chemokine transcriptomic pathways. Arthritis Research and Therapy, 25, 73. (doi: 10.1186/s13075-023-03034-6) (PMID:37131254) (PMCID:PMC10152590)

Orchard, K. J.A., Akbar, M., Crower, L. A.N., Cole, J., Millar, N. L. and Raleigh, S. M. (2023) Characterization of histone modifications in late-stage rotator cuff tendinopathy. Genes, 14(2), 496. (doi: 10.3390/genes14020496) (PMID:36833423) (PMCID:PMC9956879)

2022

Thümmler, K. , Williams, M. T.S., Kitson, S., Sood, S., Akbar, M., Cole, J. J., Goodyear, C. S. , Hunter, E. and Soutar, R. (2022) Targeting 3D chromosomal architecture at the RANK loci to suppress myeloma-driven osteoclastogenesis. OncoImmunology, 11(1), 2104070. (doi: 10.1080/2162402X.2022.2104070) (PMID:35936985) (PMCID:PMC9348127)

Prendergast, C. T., Benson, R. A. , Scales, H. E. , Bonilha, C. S., Cole, J. J., McInnes, I. , Brewer, J. M. and Garside, P. (2022) Dissecting the molecular control of immune cell accumulation in the inflamed joint. JCI Insight, 7(7), e151281. (doi: 10.1172/jci.insight.151281) (PMID:35192549) (PMCID:PMC9057592)

2021

Suzuki, M., Cole, J. J., Konno, S., Makita, H., Kimura, H., Nishimura, M. and Maciewicz, R. A. (2021) Large‐scale plasma proteomics can reveal distinct endotypes in chronic obstructive pulmonary disease and severe asthma. Clinical and Translational Allergy, 11(10), e12091. (doi: 10.1002/clt2.12091)

Cole, J. J., Faydaci, B. A., Mcguinness, D. , Shaw, R., Maciewicz, R. A., Robertson, N. A. and Goodyear, C. S. (2021) Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts. BMC Bioinformatics, 22(1), 411. (doi: 10.1186/s12859-021-04321-2)

Cole, J. J. et al. (2021) No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing. Translational Psychiatry, 11, 404. (doi: 10.1038/s41398-021-01506-4) (PMID:34294682) (PMCID:PMC8298604)

Ansalone, C. , Cole, J., Chilaka, S., Sunzini, F., Sood, S., Robertson, J., Siebert, S. , McInnes, I. B. and Goodyear, C. (2021) TNF is a homeostatic regulator of distinct epigenetically primed human osteoclast precursors. Annals of the Rheumatic Diseases, 80(6), pp. 748-757. (doi: 10.1136/annrheumdis-2020-219262) (PMID:33692019) (PMCID:PMC8142443)

Kästele, V. et al. (2021) Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection. Mucosal Immunology, 14(3), pp. 717-727. (doi: 10.1038/s41385-020-00366-3) (PMID:33414524) (PMCID:PMC8075955)

Baer, H. M. et al. (2021) P83 Understanding Differences in Serum and Mucosal Immunopathotypes in Crohn’s Disease. BSG Campus, 21-29 Jan 2021. (doi: 10.1136/gutjnl-2020-bsgcampus.158)

Latif, A.-L. et al. (2021) BRD4-mediated repression of p53 is a target for combination therapy in AML. Nature Communications, 12, 241. (doi: 10.1038/s41467-020-20378-8) (PMID:33431824) (PMCID:PMC7801601)

2020

Li, S. et al. (2020) A Synthetic Lethal Approach to Eradicate AML via Synergistic Activation of Pro-Apoptotic p53 By MDM2 and BET Inhibitors. 62nd ASH Annual Meeting and Exposition, 5-8 Dec 2020. (doi: 10.1182/blood-2020-143079)

Li, S. et al. (2020) 3102 – A Synthetic Lethality Approach to Eradicate AML via Synergistic Activation of Pro-Apoptotic p53 By MDM2 and BET Inhibitors. 49th Annual Scientific Meeting of the ISEH (International Society for Experimental Hematology), 19-21 Aug 2020. (doi: 10.1016/j.exphem.2020.09.115)

Johnsson, H., Cole, J., Wilson, G., Pingen, M., Mcmonagle, F., Holmes, S., Mcinnes, I., Siebert, S. and Graham, G. (2020) SAT0351 Chemokine Pathways Are Enriched in Psoriatic Arthritis (Psa) Skin Lesions with Increased Expression of Atypical Chemokine Receptor 2 (ACKR2). EULAR 2021, 2-5 June 2020. (doi: 10.1136/annrheumdis-2020-eular.2980)

Rodgers, L. C., Cole, J., Rattigan, K. M., Barrett, M. P. , Kurian, N., McInnes, I. B. and Goodyear, C. S. (2020) The rheumatoid synovial environment alters fatty acid metabolism in human monocytes and enhances CCL20 secretion. Rheumatology, 59(4), pp. 869-878. (doi: 10.1093/rheumatology/kez378) (PMID:31497857)

Baer, H.M. et al. (2020) P014 Identification of Crohn’s Disease Immunopathotypes. 15th Congress of ECCO, Vienna, Austria, 12–15 Feb 2020. (doi: 10.1093/ecco-jcc/jjz203.143)

2019

Thümmler, K. et al. (2019) Polarizing receptor activation dissociates Fibroblast Growth Factor 2 mediated inhibition of myelination from its neuroprotective potential. Acta Neuropathologica Communications, 7, 212. (doi: 10.1186/s40478-019-0864-6) (PMID:31856924) (PMCID:PMC6923900)

Smith, E. L., Somma, D. , Kerrigan, D., McIntyre, Z., Cole, J. J., Liang, K. L., Kiely, P. A., Keeshan, K. and Carmody, R. J. (2019) The regulation of sequence specific NF-ĸB DNA binding and transcription by IKKβ Phosphorylation of NF-ĸB p50 at Serine 80. Nucleic Acids Research, 47(21), pp. 11151-11161. (doi: 10.1093/nar/gkz873) (PMID:31598684) (PMCID:PMC6868378)

Asghar, S., Litherland, G., Meek, D., Cole, J., Lockhart, J., Goodyear, C. S. and Crilly, A. (2019) Differential Effects of Exosomes Derived from Separate Osteoarthritis Synovial Compartments: Implications for Erosive Cartilage Disease. 2019 OARSI World Congress on Osteoarthritis, Toronto, Canada, 2-5 May 2019. (doi: 10.1016/j.joca.2019.02.295)

Rodgers, L.C., Cole, J., Rattigan, K., Barrett, M.P., Kurian, N., McInnes, I.B. and Goodyear, C.S. (2019) P108/O28 Fatty Acid Oxidation Can Drive Human Monocyte Derived CCL20 in the RA Synovial Environment. 39th European Workshop for Rheumatology Research, Lyon, France, 28 Feb-2 March 2019. (doi: 10.1136/annrheumdis-2018-EWRR2019.96)

2017

Rai, T. S., Glass, M., Cole, J. J., Rather, M., Marsden, M., Neilson, M., Brock, C., Humphreys, I. R., Everett, R. D. and Adams, P. D. (2017) Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity. Nucleic Acids Research, 45(20), pp. 11673-11683. (doi: 10.1093/nar/gkx771) (PMID:28981850) (PMCID:PMC5691367)

van Tuyn, J. et al. (2017) Oncogene-expressing senescent melanocytes upregulate MhC class II, a candidate melanoma suppressor function. Journal of Investigative Dermatology, 137(10), pp. 2197-2207. (doi: 10.1016/j.jid.2017.05.030) (PMID:28647344) (PMCID:PMC5613751)

Cole, J. J. et al. (2017) Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions. Genome Biology, 18, 58. (doi: 10.1186/s13059-017-1185-3) (PMID:28351383) (PMCID:PMC5370462)

2016

Nelson, D. M. et al. (2016) Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biology, 17, 158. (doi: 10.1186/s13059-016-1017-x) (PMID:27457071) (PMCID:PMC4960804)

Correia-Melo, C. et al. (2016) Mitochondria are required for pro-ageing features of the senescent phenotype. EMBO Journal, 35, pp. 724-742. (doi: 10.15252/embj.201592862) (PMID:26848154) (PMCID:PMC4818766)

2015

Latif, A.-L., Cole, J. J., Monteiro Campos, J., Clark, W., McGarry, L., Brock, C., Newcombe, A., Keeshan, K. , Copland, M. and Adams, P. D. (2015) Dual inhibition of MDM2 and BET cooperate to eradicate acute myeloid leukemia. Blood, 126(23), p. 674. (doi: 10.1182/blood.V126.23.674.674)

MacKenzie, D. J., Robertson, N. A., Cole, J. and Adams, P. (2015) Su1996 oncogenic BRAFV600e downregulates DNMT3B and does not directly induce the CpG island hypermethylator phenotype in human colorectal adenocarcinoma. Gastroenterology, 148(4), S570. (doi: 10.1016/S0016-5085(15)31925-9)

Dikovskaya, D. et al. (2015) Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest. Cell Reports, 12(9), pp. 1483-1496. (doi: 10.1016/j.celrep.2015.07.055) (PMID:26299965) (PMCID:PMC4562906)

2014

Lund, K., Cole, J., VanderKraats, N. D., McBryan, T., Pchelintsev, N. A., Clark, W., Copland, M. , Edwards, J. R. and Adams, P. (2014) DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML. Genome Biology, 15(7), p. 406. (doi: 10.1186/s13059-014-0406-2)

Lund, K., Cole, J., McBryan, T., Copland, M. and Adams, P. (2014) Investigating effects of epigenetic modulation in acute myeloid leukaemia. Lancet, 383(Supl 1), S70. (doi: 10.1016/S0140-6736(14)60333-0) (PMID:19345831) (PMCID:PMC2866651)

Rai, T. S. et al. (2014) HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia. Genes and Development, 28(24), pp. 2712-2725. (doi: 10.1101/gad.247528.114) (PMID:25512559) (PMCID:PMC4265675)

2010

Wilson, R.H., Moran, C.N., Cole, J., Pitsiladis, Y.P. and Bailey, M.E.S. (2010) Evolutionary history of the ADRB2 gene in humans. American Journal of Human Genetics, 86(3), pp. 490-493. (doi: 10.1016/j.ajhg.2010.01.031) (PMID:20215008) (PMCID:PMC2833374)

This list was generated on Thu Nov 21 08:02:01 2024 GMT.

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