Dr David McGuinness
- Bioinformatician (MVLS Research Facilities)
telephone:
01413305196
email:
David.Mcguinness.2@glasgow.ac.uk
Glasgow Polyomics, Wolfson-Wohl Building, University of Glasgow - Garscube campus
Publications
2024
Riva, F., McGuinness, D. H. , McKeegan, D. E.F. , Peinado-Izaguerri, J. , Bruggeman, G., Hermans, D., Eckersall, P. D. , Bain, M. and McLaughlin, M. (2024) Measuring the impact of dietary supplementation with citrus or cucumber extract on chicken gut microbiota using 16s rRNA gene sequencing. Veterinary Research Communications, (doi: 10.1007/s11259-024-10417-w) (Early Online Publication)
2023
Craven, H., Erlandsson, H., McGuinness, D., McGuinness, D. , Mafra, D., Ijaz, U. Z. , Bergman, P., Shiels, P. G. and Stenvinkel, P. (2023) A normative microbiome is not restored following kidney transplantation. Clinical Science, 137(20), pp. 1563-1575. (doi: 10.1042/CS20230779) (PMID:37756543)
2022
Voss, S. J., McGuinness, D. H. , Weir, W. and Sutton, D. G.M. (2022) A study comparing the healthy and diseased equine glandular gastric microbiota sampled with sheathed transendoscopic cytology brushes. Journal of Equine Veterinary Science, (doi: 10.1016/j.jevs.2022.104002) (PMID:35490972)
2021
Cole, J. J., Faydaci, B. A., Mcguinness, D. , Shaw, R., Maciewicz, R. A., Robertson, N. A. and Goodyear, C. S. (2021) Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts. BMC Bioinformatics, 22(1), 411. (doi: 10.1186/s12859-021-04321-2)
Craven, H. et al. (2021) Socioeconomic position links circulatory microbiota differences with biological age. Scientific Reports, 11, 12629. (doi: 10.1038/s41598-021-92042-0) (PMID:34135381) (PMCID:PMC8209159)
2020
Garber, A. , Hastie, P.M. , Farci, V., McGuinness, D. , Bulmer, L., Alzahal, O. and Murray, J.M.D. (2020) The effect of supplementing pony diets with yeast on 2. The faecal microbiome. Animal, 14(12), pp. 2493-2502. (doi: 10.1017/S1751731120001512) (PMID:32580805)
Garber, A. , Hastie, P. , McGuinness, D. , Malarange, P. and Murray, J.-A. (2020) Abrupt dietary changes between grass and hay alter faecal microbiota of ponies. PLoS ONE, 15(8), e0237869. (doi: 10.1371/journal.pone.0237869) (PMID:32810164) (PMCID:PMC7446798)
2019
Taponen, S., Mcguinness, D. , Hiitiö, H., Simojoki, H., Zadoks, R. and Pyörälä, S. (2019) Bovine milk microbiome: a more complex issue than expected. Veterinary Research, 50, 44. (doi: 10.1186/s13567-019-0662-y) (PMID:31171032) (PMCID:PMC6555717)
2018
Ciosi, M. , Cumming, S. A., Alshammari, A. M., Symeonidi, E., Herzyk, P. , Mcguinness, D. , Galbraith, J., Hamilton, G. and Monckton, D. G. (2018) Library preparation and MiSeq sequencing for the genotyping-by-sequencing of the Huntington disease HTT exon one trinucleotide repeat and the quantification of somatic mosaicism [Protocol]. Other. Springer Nature. (doi: 10.21203/rs.2.1581/v2).
2014
Mcguinness, D.H. and McGuinness, D. (2014) m6a RNA methylation: the implications for health and disease. Journal of Cancer Science and Clinical Oncology, 1(1), 105. (doi: 10.15744/2394-6520.1.105)
2011
McGuinness, D., McGuinness, D.H. , McCaul, J. and Shiels, P.G. (2011) Sirtuins, bioageing, and cancer. Journal of Aging Research, 2011, 235754. (doi: 10.4061/2011/235754) (PMID:21766030) (PMCID:PMC3134127)
Mukherjee, R., Mcguinness, D.H. , McCall, P., Underwood, M. A., Seywright, M., Orange, C. and Edwards, J. (2011) Upregulation of MAPK pathway is associated with survival in castrate-resistant prostate cancer. British Journal of Cancer, 104(12), pp. 1920-1928. (doi: 10.1038/bjc.2011.163) (PMID:21559022) (PMCID:PMC3111196)
2008
Piestrzeniewicz-Ulanska, D., McGuinness, D.H. and Yeaman, G.R. (2008) TGF-β signaling in endometrial cancer. In: Jakowlew, S.B. (ed.) Transforming Growth Factor-β in Cancer Therapy. Series: Cancer Drug Discovery and Development, 2. Humana Press: Totowa, NJ, pp. 63-78. ISBN 9781588297150 (doi: 10.1007/978-1-59745-293-9_5)
2003
McGuinness, D. H. , Dehal, P. K. and Pleass, R. J. (2003) Pattern recognition molecules and innate immunity to parasites. Trends in Parasitology, 19(7), pp. 312-319. (doi: 10.1016/S1471-4922(03)00123-5) (PMID:12855382)
Pleass, R. J., Ogun, S. A., McGuinness, D. H. , van de Winkel, J. G.J., Holder, A. A. and Woof, J. M. (2003) Novel antimalarial antibodies highlight the importance of the antibody Fc region in mediating protection. Blood, 102(13), pp. 4424-4430. (doi: 10.1182/blood-2003-02-0583) (PMID:12855589)
2002
Mcguinness, D.H. , Pleass, R.J., Senior, B.W. and Woof, J.M. (2002) Chimeric human antibodies directed against a major surface antigen of Pseudomonas aeruginosa. Biochemical Society Transactions, 30(3), A92.3-A92. (doi: 10.1042/bst030a092b)
Pleass, R.J., McGuinness, D.H. , Holder, A.A. and Woof, J.M. (2002) Anti-malaria immune effector mechanisms recruited by human IgG1 and IgA1 monoclonal antibodies. Biochemical Society Transactions, 30(3), A92.1-A92. (doi: 10.1042/bst030a092)
Articles
Riva, F., McGuinness, D. H. , McKeegan, D. E.F. , Peinado-Izaguerri, J. , Bruggeman, G., Hermans, D., Eckersall, P. D. , Bain, M. and McLaughlin, M. (2024) Measuring the impact of dietary supplementation with citrus or cucumber extract on chicken gut microbiota using 16s rRNA gene sequencing. Veterinary Research Communications, (doi: 10.1007/s11259-024-10417-w) (Early Online Publication)
Craven, H., Erlandsson, H., McGuinness, D., McGuinness, D. , Mafra, D., Ijaz, U. Z. , Bergman, P., Shiels, P. G. and Stenvinkel, P. (2023) A normative microbiome is not restored following kidney transplantation. Clinical Science, 137(20), pp. 1563-1575. (doi: 10.1042/CS20230779) (PMID:37756543)
Voss, S. J., McGuinness, D. H. , Weir, W. and Sutton, D. G.M. (2022) A study comparing the healthy and diseased equine glandular gastric microbiota sampled with sheathed transendoscopic cytology brushes. Journal of Equine Veterinary Science, (doi: 10.1016/j.jevs.2022.104002) (PMID:35490972)
Cole, J. J., Faydaci, B. A., Mcguinness, D. , Shaw, R., Maciewicz, R. A., Robertson, N. A. and Goodyear, C. S. (2021) Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts. BMC Bioinformatics, 22(1), 411. (doi: 10.1186/s12859-021-04321-2)
Craven, H. et al. (2021) Socioeconomic position links circulatory microbiota differences with biological age. Scientific Reports, 11, 12629. (doi: 10.1038/s41598-021-92042-0) (PMID:34135381) (PMCID:PMC8209159)
Garber, A. , Hastie, P.M. , Farci, V., McGuinness, D. , Bulmer, L., Alzahal, O. and Murray, J.M.D. (2020) The effect of supplementing pony diets with yeast on 2. The faecal microbiome. Animal, 14(12), pp. 2493-2502. (doi: 10.1017/S1751731120001512) (PMID:32580805)
Garber, A. , Hastie, P. , McGuinness, D. , Malarange, P. and Murray, J.-A. (2020) Abrupt dietary changes between grass and hay alter faecal microbiota of ponies. PLoS ONE, 15(8), e0237869. (doi: 10.1371/journal.pone.0237869) (PMID:32810164) (PMCID:PMC7446798)
Taponen, S., Mcguinness, D. , Hiitiö, H., Simojoki, H., Zadoks, R. and Pyörälä, S. (2019) Bovine milk microbiome: a more complex issue than expected. Veterinary Research, 50, 44. (doi: 10.1186/s13567-019-0662-y) (PMID:31171032) (PMCID:PMC6555717)
Mcguinness, D.H. and McGuinness, D. (2014) m6a RNA methylation: the implications for health and disease. Journal of Cancer Science and Clinical Oncology, 1(1), 105. (doi: 10.15744/2394-6520.1.105)
McGuinness, D., McGuinness, D.H. , McCaul, J. and Shiels, P.G. (2011) Sirtuins, bioageing, and cancer. Journal of Aging Research, 2011, 235754. (doi: 10.4061/2011/235754) (PMID:21766030) (PMCID:PMC3134127)
Mukherjee, R., Mcguinness, D.H. , McCall, P., Underwood, M. A., Seywright, M., Orange, C. and Edwards, J. (2011) Upregulation of MAPK pathway is associated with survival in castrate-resistant prostate cancer. British Journal of Cancer, 104(12), pp. 1920-1928. (doi: 10.1038/bjc.2011.163) (PMID:21559022) (PMCID:PMC3111196)
McGuinness, D. H. , Dehal, P. K. and Pleass, R. J. (2003) Pattern recognition molecules and innate immunity to parasites. Trends in Parasitology, 19(7), pp. 312-319. (doi: 10.1016/S1471-4922(03)00123-5) (PMID:12855382)
Pleass, R. J., Ogun, S. A., McGuinness, D. H. , van de Winkel, J. G.J., Holder, A. A. and Woof, J. M. (2003) Novel antimalarial antibodies highlight the importance of the antibody Fc region in mediating protection. Blood, 102(13), pp. 4424-4430. (doi: 10.1182/blood-2003-02-0583) (PMID:12855589)
Mcguinness, D.H. , Pleass, R.J., Senior, B.W. and Woof, J.M. (2002) Chimeric human antibodies directed against a major surface antigen of Pseudomonas aeruginosa. Biochemical Society Transactions, 30(3), A92.3-A92. (doi: 10.1042/bst030a092b)
Pleass, R.J., McGuinness, D.H. , Holder, A.A. and Woof, J.M. (2002) Anti-malaria immune effector mechanisms recruited by human IgG1 and IgA1 monoclonal antibodies. Biochemical Society Transactions, 30(3), A92.1-A92. (doi: 10.1042/bst030a092)
Book Sections
Piestrzeniewicz-Ulanska, D., McGuinness, D.H. and Yeaman, G.R. (2008) TGF-β signaling in endometrial cancer. In: Jakowlew, S.B. (ed.) Transforming Growth Factor-β in Cancer Therapy. Series: Cancer Drug Discovery and Development, 2. Humana Press: Totowa, NJ, pp. 63-78. ISBN 9781588297150 (doi: 10.1007/978-1-59745-293-9_5)
Research Reports or Papers
Ciosi, M. , Cumming, S. A., Alshammari, A. M., Symeonidi, E., Herzyk, P. , Mcguinness, D. , Galbraith, J., Hamilton, G. and Monckton, D. G. (2018) Library preparation and MiSeq sequencing for the genotyping-by-sequencing of the Huntington disease HTT exon one trinucleotide repeat and the quantification of somatic mosaicism [Protocol]. Other. Springer Nature. (doi: 10.21203/rs.2.1581/v2).
Research datasets
2020
Garber, A. , Hastie, P. , Mcguinness, D. and Murray, J.-A. (2020) The effect of synbiotic supplement on equine faecal microbiota following abrupt dietary changes. [Data Collection]
Garber, A. , Hastie, P. , Mcguinness, D. , Malarange, P. and Murray, J.-A. (2020) Abrupt dietary changes between grass and hay alter faecal microbiota of ponies. [Data Collection]
2019
Garber, A. , Hastie, P. , Farci, V., Mcguinness, D. , Bulmer, L., Alzahal, O. and Murray, J. (2019) Yeast effect on faecal microbiome in ponies. [Data Collection]