2024

Aman, A. , Slob, E. A.W., Ward, J. , Sattar, N. and Strawbridge, R. (2024) Investigating the association of the effect of genetically proxied PCSK9i with mood disorders using cis-pQTLs: A drug-target Mendelian randomization study. PLoS ONE, 19(9), e0310396. (doi: 10.1371/journal.pone.0310396) (PMID:39325747)

Da Silva Costa, A. , Masson, R. , Lindsay, S. , Aman, A. and Graham, L. (2024) Virtual Reality as a Tool for Teaching Employable, Practical Skills in Science-Based Degrees. The 12th European Conference on Education (ECE2024), London, UK, 11-15 July 2024.

2023

Forsyth, L., Aman, A. , Cullen, B. , Graham, N., Lyall, D. M. , Lyall, L. M., Pell, J. P. , Ward, J. , Smith, D. J. and Strawbridge, R. J. (2023) Genetic architecture of DCC and influence on psychological, psychiatric and cardiometabolic traits in multiple ancestry groups in UK Biobank. Journal of Affective Disorders, 339, pp. 943-953. (doi: 10.1016/j.jad.2023.07.052) (PMID:37487843)

Du Toit, C. et al. (2023) Survey and evaluation of hypertension machine learning research. Journal of the American Heart Association, 12(9), e027896. (doi: 10.1161/JAHA.122.027896) (PMID:37119074) (PMCID:PMC10227215)

2022

Aman, A. , Slob, E. A.W., Ward, J. , Cullen, B. , Graham, N., Lyall, D. M. , Sattar, N. and Strawbridge, R. J. (2022) Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomization. PLoS ONE, 17(12), e0279381. (doi: 10.1371/journal.pone.0279381) (PMID:36580462) (PMCID:PMC9799310)

Hay, R., Cullen, B. , Graham, N., Lyall, D. M. , Aman, A. , Pell, J. P. , Ward, J. , Smith, D. J. and Strawbridge, R. J. (2022) Genetic analysis of the PCSK9 locus in psychological, psychiatric, metabolic and cardiovascular traits in UK Biobank. European Journal of Human Genetics, 30(12), pp. 1380-1390. (doi: 10.1038/s41431-022-01107-9) (PMID:35501368) (PMCID:PMC9712543)

Kulyté, A., Aman, A. , Strawbridge, R. J. , Arner, P. and Dahlman, I. A. (2022) Genome-wide association study identifies genetic loci associated with fat cell number and overlap with genetic risk loci for type 2 diabetes. Diabetes, 71(6), pp. 1350-1362. (doi: 10.2337/db21-0804) (PMID:35320353)

2021

McCallum, L., Brooksbank, K., McConnachie, A. , Aman, A. , Lip, S. , Dawson, J. , MacIntyre, I. M., MacDonald, T. M., Webb, D. J. and Padmanabhan, S. (2021) Rationale and design of the genotype-blinded trial of torasemide for the treatment of hypertension (BHF UMOD). American Journal of Hypertension, 34(1), pp. 92-99. (doi: 10.1093/ajh/hpaa166) (PMID:33084880) (PMCID:PMC7891239)

2020

Ford, T. J. et al. (2020) Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction. European Heart Journal, 41(34), pp. 3239-3252. (doi: 10.1093/eurheartj/ehz915) (PMID:31972008) (PMCID:PMC7557475)

2019

Menni, C. et al. (2019) Metabolomic profiling identifies novel associations with electrolyte and acid-base homeostatic patterns. Scientific Reports, 9, 15088. (doi: 10.1038/s41598-019-51492-3) (PMID:31636301) (PMCID:PMC6803625)

Jones, F. E. et al. (2019) 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease. Human Molecular Genetics, 28(4), pp. 628-638. (doi: 10.1093/hmg/ddy369) (PMID:30351356) (PMCID:PMC6360271)

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genetics of hypertension and heart failure. In: Dorobantu, M., Mancia, G., Grassi, G. and Voicu, V. (eds.) Hypertension and Heart Failure. Series: Updates in hypertension and cardiovascular protection. Springer International Publishing, pp. 15-29. ISBN 9783319933191

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genomics of hypertension. In: Touyz, R.M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer, pp. 171-181. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_16)

2018

Graham, L. A., Aman, A. , Campbell, D. D. , Augley, J., Graham, D. , McBride, M. W. , Fraser, N. J., Ferreri, N. R., Dominiczak, A. F. and Padmanabhan, S. (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50(11), pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018) (PMID:30216136) (PMCID:PMC6293113)

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2018) Recent findings in the genetics of blood pressure: how to apply in practice or is a moonshot required? Current Hypertension Reports, 20, 54. (doi: 10.1007/s11906-018-0863-1) (PMID:29881931) (PMCID:PMC5992231)

2017

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2017) Genomics of hypertension. Pharmacological Research, 121, pp. 219-229. (doi: 10.1016/j.phrs.2017.04.031) (PMID:28495658)

Articles

Aman, A. , Slob, E. A.W., Ward, J. , Sattar, N. and Strawbridge, R. (2024) Investigating the association of the effect of genetically proxied PCSK9i with mood disorders using cis-pQTLs: A drug-target Mendelian randomization study. PLoS ONE, 19(9), e0310396. (doi: 10.1371/journal.pone.0310396) (PMID:39325747)

Forsyth, L., Aman, A. , Cullen, B. , Graham, N., Lyall, D. M. , Lyall, L. M., Pell, J. P. , Ward, J. , Smith, D. J. and Strawbridge, R. J. (2023) Genetic architecture of DCC and influence on psychological, psychiatric and cardiometabolic traits in multiple ancestry groups in UK Biobank. Journal of Affective Disorders, 339, pp. 943-953. (doi: 10.1016/j.jad.2023.07.052) (PMID:37487843)

Du Toit, C. et al. (2023) Survey and evaluation of hypertension machine learning research. Journal of the American Heart Association, 12(9), e027896. (doi: 10.1161/JAHA.122.027896) (PMID:37119074) (PMCID:PMC10227215)

Aman, A. , Slob, E. A.W., Ward, J. , Cullen, B. , Graham, N., Lyall, D. M. , Sattar, N. and Strawbridge, R. J. (2022) Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomization. PLoS ONE, 17(12), e0279381. (doi: 10.1371/journal.pone.0279381) (PMID:36580462) (PMCID:PMC9799310)

Hay, R., Cullen, B. , Graham, N., Lyall, D. M. , Aman, A. , Pell, J. P. , Ward, J. , Smith, D. J. and Strawbridge, R. J. (2022) Genetic analysis of the PCSK9 locus in psychological, psychiatric, metabolic and cardiovascular traits in UK Biobank. European Journal of Human Genetics, 30(12), pp. 1380-1390. (doi: 10.1038/s41431-022-01107-9) (PMID:35501368) (PMCID:PMC9712543)

Kulyté, A., Aman, A. , Strawbridge, R. J. , Arner, P. and Dahlman, I. A. (2022) Genome-wide association study identifies genetic loci associated with fat cell number and overlap with genetic risk loci for type 2 diabetes. Diabetes, 71(6), pp. 1350-1362. (doi: 10.2337/db21-0804) (PMID:35320353)

McCallum, L., Brooksbank, K., McConnachie, A. , Aman, A. , Lip, S. , Dawson, J. , MacIntyre, I. M., MacDonald, T. M., Webb, D. J. and Padmanabhan, S. (2021) Rationale and design of the genotype-blinded trial of torasemide for the treatment of hypertension (BHF UMOD). American Journal of Hypertension, 34(1), pp. 92-99. (doi: 10.1093/ajh/hpaa166) (PMID:33084880) (PMCID:PMC7891239)

Ford, T. J. et al. (2020) Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction. European Heart Journal, 41(34), pp. 3239-3252. (doi: 10.1093/eurheartj/ehz915) (PMID:31972008) (PMCID:PMC7557475)

Menni, C. et al. (2019) Metabolomic profiling identifies novel associations with electrolyte and acid-base homeostatic patterns. Scientific Reports, 9, 15088. (doi: 10.1038/s41598-019-51492-3) (PMID:31636301) (PMCID:PMC6803625)

Jones, F. E. et al. (2019) 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease. Human Molecular Genetics, 28(4), pp. 628-638. (doi: 10.1093/hmg/ddy369) (PMID:30351356) (PMCID:PMC6360271)

Graham, L. A., Aman, A. , Campbell, D. D. , Augley, J., Graham, D. , McBride, M. W. , Fraser, N. J., Ferreri, N. R., Dominiczak, A. F. and Padmanabhan, S. (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50(11), pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018) (PMID:30216136) (PMCID:PMC6293113)

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2018) Recent findings in the genetics of blood pressure: how to apply in practice or is a moonshot required? Current Hypertension Reports, 20, 54. (doi: 10.1007/s11906-018-0863-1) (PMID:29881931) (PMCID:PMC5992231)

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2017) Genomics of hypertension. Pharmacological Research, 121, pp. 219-229. (doi: 10.1016/j.phrs.2017.04.031) (PMID:28495658)

Book Sections

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genetics of hypertension and heart failure. In: Dorobantu, M., Mancia, G., Grassi, G. and Voicu, V. (eds.) Hypertension and Heart Failure. Series: Updates in hypertension and cardiovascular protection. Springer International Publishing, pp. 15-29. ISBN 9783319933191

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genomics of hypertension. In: Touyz, R.M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer, pp. 171-181. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_16)

Conference or Workshop Item

Da Silva Costa, A. , Masson, R. , Lindsay, S. , Aman, A. and Graham, L. (2024) Virtual Reality as a Tool for Teaching Employable, Practical Skills in Science-Based Degrees. The 12th European Conference on Education (ECE2024), London, UK, 11-15 July 2024.