Professor Peter Uhlhaas
- Affiliate (School of Psychology & Neuroscience)
email:
Peter.Uhlhaas@glasgow.ac.uk
R604 Level 6, 62 Hillhead Street, Glasgow G12 8QB
Research interests
I obtained a BSc and PhD in Psychology from the University of Stirling, Scotland. I was a visiting researcher at Weill Medical College, Cornell University, New York (2001-2002), before joining the Max-Planck Institute for Brain Research in Frankfurt, Germany, where I became a group leader in 2006, investigating the neurophysiology of cognitive dysfunctions in schizophrenia and adolescent brain development. In addition to my work in clinical and developmental cognitive neuroscience, I completed a training in psychodynamic therapy. I joined the Institute of Neuroscience and Psychology as a Reader in August 2012.
My current research interests are:
1) Neurophysiology of Cognitive Deficits and Symptoms in Schizophrenia
2) Cognition and Physiology of Adolescent Brain Maturation
3) Neural Oscillations and their Role in Cognition and Perception
4) Autism Spectrum Disorders
Publications
2024
Grent-'T-Jong, T. , Dheerendra, P. , Fusar-Poli, P., Gross, J. , Gumley, A. I. , Krishnadas, R. , Muckli, L. and Uhlhaas, P. (2024) Entrainment of neural oscillations during language processing in early-stage schizophrenia. NeuroImage: Clinical, (doi: 10.1016/j.nicl.2024.103695) (Early Online Publication)
Bianciardi, B., Mastek, H., Franka, M. and Uhlhaas, P. J. (2024) Effects of N-Methyl-D-aspartate receptor antagonists on gamma-band activity during auditory stimulation compared with electro/magneto-encephalographic data in schizophrenia and early-stage psychosis: a systematic review and perspective. Schizophrenia Bulletin, (doi: 10.1093/schbul/sbae090) (PMID:38934800) (Early Online Publication)
Smith, K. A. et al. (2024) Digital mental health for schizophrenia and other severe mental illnesses: an international consensus on current challenges and potential solutions. JMIR Mental Health, 11, e57155. (doi: 10.2196/57155) (PMID:38717799) (PMCID:PMC11112473)
Torous, J. et al. (2024) Digital health interventions for schizophrenia: setting standards for mental health. Schizophrenia Research, 267, pp. 392-395. (doi: 10.1016/j.schres.2024.04.013) (PMID:38640849)
Metzner, C., Dimulescu, C., Kamp, F., Fromm, S., Uhlhaas, P. J. and Obermayer, K. (2024) Exploring global and local processes underlying alterations in resting-state functional connectivity and dynamics in schizophrenia. Frontiers in Psychiatry, 15, 1352641. (doi: 10.3389/fpsyt.2024.1352641) (PMID:38414495) (PMCID:PMC10897003)
Allen, P. et al. (2024) Normative modeling of brain morphometry in clinical high risk for psychosis. JAMA Psychiatry, 81(1), pp. 77-88. (doi: 10.1001/jamapsychiatry.2023.3850) (PMID:37819650) (PMCID:PMC10568447)
Dheerendra, P. , Grent-'t-Jong, T. , Gajwani, R. , Gross, J. , Gumley, A. I. , Krishnadas, R. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2024) Intact mismatch negativity responses in clinical high-risk for psychosis and first-episode psychosis: evidence from source-reconstructed event-related fields and time-frequency data. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 9(1), pp. 121-131. (doi: 10.1016/j.bpsc.2023.09.006) (PMID:37778724)
2023
Grent-'T-Jong, T. , Brickweddle, M., Metzner, C. and Uhlhaas, P. J. (2023) 40 Hz auditory steady state responses in schizophrenia: towards a mechanistic biomarker for circuit dysfunctions and early detection and diagnosis. Biological Psychiatry, 94(7), pp. 550-560. (doi: 10.1016/j.biopsych.2023.03.026) (PMID:37086914)
Hua, L. et al. (2023) Thalamo-cortical circuits during sensory attenuation in emerging psychosis: a combined magnetoencephalography and dynamic causal modelling study. npj Schizophrenia, 9, 25. (doi: 10.1038/s41537-023-00341-4) (PMID:37117187) (PMCID:PMC10147678)
Cooper, S. M., Fusar-Poli, P. and Uhlhaas, P. J. (2023) Characteristics and clinical correlates of risk symptoms in individuals at clinical high-risk for psychosis: a systematic review and meta-analysis. Schizophrenia Research, 254, pp. 54-61. (doi: 10.1016/j.schres.2023.02.011) (PMID:36801514)
Bianciardi, B., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Moelling, M., Schwannauer, M., Schultze-Lutter, F., Fracasso, A. and Uhlhaas, P. J. (2023) Investigating temporal and prosodic markers in clinical high-risk for psychosis participants using automated acoustic analysis. Early Intervention in Psychiatry, 17(3), pp. 327-330. (doi: 10.1111/eip.13357) (PMID:36205386)
2022
Mancini, V., Rochas, V., Seeber, M., Grent-'t-Jong, T. , Rihs, T. A., Latrèche, C., Uhlhaas, P. J. , Michel, C. M. and Eliez, S. (2022) Oscillatory neural signatures of visual perception across developmental stages in individuals with 22q11.2 deletion syndrome. Biological Psychiatry, 92(5), pp. 407-418. (doi: 10.1016/j.biopsych.2022.02.961) (PMID:35550793)
Baldwin, H. et al. (2022) Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis. Translational Psychiatry, 12, 297. (doi: 10.1038/s41398-022-02057-y) (PMID:35882855) (PMCID:PMC9325730)
Haining, K. et al. (2022) Computerised cognitive training during early-stage psychosis improves cognitive deficits and gamma-band oscillations: a pilot study. Schizophrenia Research, 243, pp. 217-219. (doi: 10.1016/j.schres.2022.04.001) (PMID:35461044)
Haining, K., Gajwani, R. , Gross, J. , Gumley, A. I. , Ince, R. A.A. , Lawrie, S. M., Schultze-Lutter, F., Schwannauer, M. and Uhlhaas, P. J. (2022) Characterising cognitive heterogeneity in individuals at clinical high-risk for psychosis: a cluster analysis with clinical and functional outcome prediction. European Archives of Psychiatry and Clinical Neuroscience, 272(3), pp. 437-448. (doi: 10.1007/s00406-021-01315-2) (PMID:34401957)
Grent-'t-Jong, T. , Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F., Williams, S. R. and Uhlhaas, P. J. (2022) MR-spectroscopy of GABA and glutamate/glutamine concentrations in auditory cortex in clinical high-risk for psychosis individuals. Frontiers in Psychiatry, 13, 859322. (doi: 10.3389/fpsyt.2022.859322) (PMID:35422722) (PMCID:PMC9002006)
Mancini, V., Rochas, V., Seeber, M., Roehri, N., Rihs, T. A., Ferat, V., Schneider, M., Uhlhaas, P. J. , Eliez, S. and Michel, C. M. (2022) Aberrant developmental patterns of gamma-band response and long-range communication disruption in youths with 22q11.2 deletion syndrome. American Journal of Psychiatry, 179(3), pp. 204-215. (doi: 10.1176/appi.ajp.2021.21020190) (PMID:35236117)
Brunner, G., Gajwani, R. , Gross, J. , Gumley, A. I. , Krishnadas, R. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F., Fracasso, A. and Uhlhaas, P. J. (2022) Hippocampal structural alterations in early-stage psychosis: specificity and relationship to clinical outcomes. NeuroImage: Clinical, 35, 103087. (doi: 10.1016/j.nicl.2022.103087) (PMID:35780662) (PMCID:PMC9421451)
Kambeitz-Ilankovic, L., Rzayeva, U., Völkel, L., Wenzel, J., Weiske, J., Jessen, F., Reininghaus, U., Uhlhaas, P. J. , Alvarez-Jimenez, M. and Kambeitz, J. (2022) A systematic review of digital and face-to-face cognitive behavioral therapy for depression. npj Digital Medicine, 5, 144. (doi: 10.1038/s41746-022-00677-8) (PMID:36109583) (PMCID:PMC9476400)
2021
Grent-'t-Jong, T. , Melloni, L. and Uhlhaas, P. J. (2021) Dissociation and brain rhythms: pitfalls and promises. Frontiers in Psychiatry, 12, 790372. (doi: 10.3389/fpsyt.2021.790372)
Haining, K., Karagiorgou, O., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2021) Prevalence and predictors of suicidality and non-suicidal self-harm among individuals at clinical high-risk for psychosis: results from a community-recruited sample. Early Intervention in Psychiatry, 15(5), pp. 1256-1265. (doi: 10.1111/eip.13075) (PMID:33372364) (PMCID:PMC8451831)
Grent-'T-Jong, T. , Gajwani, R. , Gross, J. , Gumley, A. I. , Krishnadas, R. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2021) 40-Hz auditory steady-state responses characterize circuit dysfunctions and predict clinical outcomes in clinical-high-risk participants: a magnetoencephalography study. Biological Psychiatry, 90(6), pp. 419-429. (doi: 10.1016/j.biopsych.2021.03.018) (PMID:34116790)
Bianciardi, B. and Uhlhaas, P. J. (2021) Do NMDA-R antagonists re-create patterns of spontaneous gamma-band activity in schizophrenia? A systematic review and perspective. Neuroscience and Biobehavioral Reviews, 124, pp. 308-323. (doi: 10.1016/j.neubiorev.2021.02.005) (PMID:33581223)
Haining, K., Brunner, G., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2021) The relationship between cognitive deficits and impaired short-term functional outcome in clinical high-risk for psychosis participants: a machine learning and modelling approach. Schizophrenia Research, 231, pp. 24-31. (doi: 10.1016/j.schres.2021.02.019) (PMID:33744682)
Cruz, G. , Grent-'t-Jong, T. , Krishnadas, R. , Palva, J. M. , Palva, S. and Uhlhaas, P. J. (2021) Long range temporal correlations (LRTCs) in MEG-data during emerging psychosis: relationship to symptoms, medication-status and clinical trajectory. NeuroImage: Clinical, 31, 102722. (doi: 10.1016/j.nicl.2021.102722) (PMID:34130193) (PMCID:PMC8209846)
Staines, L., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2021) Duration of basic and attenuated-psychotic symptoms in individuals at clinical high risk for psychosis: pattern of symptom onset and effects of duration on functioning and cognition. BMC Psychiatry, 21, 339. (doi: 10.1186/s12888-021-03267-2) (PMID:34233651) (PMCID:PMC8265048)
2020
Zikidi, K., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F., Fracasso, A. and Uhlhaas, P. J. (2020) Grey-matter abnormalities in clinical high-risk participants for psychosis. Schizophrenia Research, 226, pp. 120-128. (doi: 10.1016/j.schres.2019.08.034) (PMID:31740178) (PMCID:PMC7774586)
Kocsis, A., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F., Grent-'t-Jong, T. and Uhlhaas, P. J. (2020) Altered autonomic function in individuals at clinical high risk for psychosis. Frontiers in Psychiatry, 11, 580503. (doi: 10.3389/fpsyt.2020.580503)
Hua, L., Recasens, M., Grent-'T-Jong, T. , Adams, R. A., Gross, J. and Uhlhaas, P. J. (2020) Investigating cortico-subcortical circuits during auditory sensory attenuation: a combined magnetoencephalographic and dynamic causal modelling study. Human Brain Mapping, 41(15), pp. 4419-4430. (doi: 10.1002/hbm.25134) (PMID:32662585) (PMCID:PMC7502827)
Grent-'T-Jong, T. , Gajwani, R. , Gross, J. , Gumley, A. I. , Krishnadas, R. , Lawrie, S., Schwannauer, M., Schultze-Lutte, F. and Uhlhaas, P. (2020) Association of magnetoencephalographically measured high-frequency oscillations in visual cortex with circuit dysfunctions in local and large-scale networks during emerging psychosis. JAMA Psychiatry, 77(8), pp. 852-862. (doi: 10.1001/jamapsychiatry.2020.0284) (PMID:32211834) (PMCID:PMC7097849)
Kostova, R. , Cecere, R., Thut, G. and Uhlhaas, P. J. (2020) Targeting cognition in schizophrenia through transcranial direct current stimulation: a systematic review and perspective. Schizophrenia Research, 220, pp. 300-310. (doi: 10.1016/j.schres.2020.03.002) (PMID:32204971)
Grent-'T-Jong, T. and Uhlhaas, P. J. (2020) The many facets of mismatch negativity. Biological Psychiatry, 87(8), pp. 695-696. (doi: 10.1016/j.biopsych.2020.01.022) (PMID:32216902)
Haining, K., Matrunola, C., Mitchell, L., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2020) Neuropsychological deficits in participants at clinical high risk for psychosis recruited from the community: relationships to functioning and clinical symptoms. Psychological Medicine, 50(1), pp. 77-85. (doi: 10.1017/S0033291718003975) (PMID:30862319)
2019
Fusar-Poli, P., Sullivan, S. A., Shah, J. L. and Uhlhaas, P. J. (2019) Improving the detection of individuals at clinical risk for psychosis in the community, primary and secondary care: An integrated evidence-based approach. Frontiers in Psychiatry, 10, 774. (doi: 10.3389/fpsyt.2019.00774) (PMID:31708822) (PMCID:PMC6822017)
Uhlhaas, P. and Torous, J. (2019) Digital tools for youth mental health. npj Digital Medicine, 2, 104. (doi: 10.1038/s41746-019-0181-2) (PMID:31646184) (PMCID:PMC6802195)
Reilly, T., Mechelli, A., McGuire, P., Fusar-Poli, P. and Uhlhaas, P. J. (2019) E-Clinical high risk for psychosis: Viewpoint on potential of digital innovations for preventive psychiatry. JMIR Mental Health, 6(10), e14581. (doi: 10.2196/14581) (PMID:31584006)
Nikitova, N., Keane, B. P., Demmin, D., Silverstein, S. M. and Uhlhaas, P. J. (2019) The Audio-Visual Abnormalities Questionnaire (AVAQ): Development and validation of a new instrument for assessing anomalies in sensory perception in schizophrenia spectrum disorders. Schizophrenia Research, 209, pp. 227-233. (doi: 10.1016/j.schres.2019.03.016) (PMID:31182320)
McDonald, M., Christoforidou, E., Van Rijsbergen, N. , Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. (2019) Using online-screening in the general population to detect participants at clinical high-risk for psychosis. Schizophrenia Bulletin, 45(3), pp. 600-609. (doi: 10.1093/schbul/sby069) (PMID:29889271) (PMCID:PMC6483579)
Mikanmaa, E., Grent-'t-Jong, T. , Hua, L., Recasens, M., Thune, H. and Uhlhaas, P. J. (2019) Towards a neurodynamical understanding of the prodrome in schizophrenia. NeuroImage, 190, pp. 144-153. (doi: 10.1016/j.neuroimage.2017.11.026) (PMID:29175199)
2018
Sterzer, P., Adams, R. A., Fletcher, P., Frith, C., Lawrie, S. M., Muckli, L. , Petrovic, P., Uhlhaas, P. , Voss, M. and Corlett, P. R. (2018) The predictive coding account of psychosis. Biological Psychiatry, 84(9), pp. 634-643. (doi: 10.1016/j.biopsych.2018.05.015) (PMID:30007575) (PMCID:PMC6169400)
Grent-‘t-Jong, T. et al. (2018) Resting-state gamma-band power alterations in schizophrenia reveal functional E/I-balance abnormalities across illness-stages. eLife, 7, e37799. (doi: 10.7554/eLife.37799) (PMID:30260771) (PMCID:PMC6160226)
Recasens, M., Gross, J. and Uhlhaas, P. J. (2018) Low-frequency oscillatory correlates of auditory predictive processing in cortical-subcortical networks: a MEG-study. Scientific Reports, 8, 14007. (doi: 10.1038/s41598-018-32385-3) (PMID:30228366) (PMCID:PMC6143554)
Uhlhaas, P. J. , Grent-'t-Jong, T. and Gross, J. (2018) Magnetoencephalography and translational neuroscience in psychiatry. JAMA Psychiatry, 75(9), pp. 969-971. (doi: 10.1001/jamapsychiatry.2018.0775) (PMID:29799913)
Grent-'t-Jong, T. et al. (2018) Acute ketamine dysregulates task-related gamma-band oscillations in thalamo-cortical circuits in schizophrenia. Brain, 141(8), pp. 2511-2526. (doi: 10.1093/brain/awy175) (PMID:30020423) (PMCID:PMC6061682)
2017
Sauer, A. et al. (2017) Impairment in predictive processes during auditory mismatch negativity in ScZ: evidence from event-related fields. Human Brain Mapping, 38(10), pp. 5082-5093. (doi: 10.1002/hbm.23716) (PMID:28677252)
Recasens, M. and Uhlhaas, P. J. (2017) Test-retest reliability of the magnetic mismatch negativity response to sound duration and omission deviants. NeuroImage, 157, pp. 184-195. (doi: 10.1016/j.neuroimage.2017.05.064) (PMID:28576412)
Uhlhaas, P. J. , Liddle, P., Linden, D. E.J., Nobre, A. C., Singh, K. D. and Gross, J. (2017) Magnetoencephalography as a tool in psychiatric research: current status and perspective. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2(3), pp. 235-244. (doi: 10.1016/j.bpsc.2017.01.005) (PMID:28424797) (PMCID:PMC5387180)
Pratt, J., Dawson, N., Morris, B. J. , Grent-'T-Jong, T. , Roux, F. and Uhlhaas, P. J. (2017) Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations: a unique window into the origins of ScZ? Schizophrenia Research, 180, pp. 4-12. (doi: 10.1016/j.schres.2016.05.013) (PMID:27317361)
Uhlhaas, P. J. , Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M. and Schwannauer, M. (2017) The Youth Mental Health Risk and Resilience Study (YouR-Study). BMC Psychiatry, 17, 43. (doi: 10.1186/s12888-017-1206-5) (PMID:28125984) (PMCID:PMC5270216)
Hirvonen, J., Wibral, M., Palva, J. M. , Singer, W., Uhlhaas, P. and Palva, S. (2017) Whole-brain source-reconstructed MEG-data reveal reduced long-range synchronization in chronic schizophrenia. eNeuro, 4(5), e0338-17.2. (doi: 10.1523/ENEURO.0338-17.2017) (PMID:29085902) (PMCID:PMC5659261)
2016
Thuné, H., Recasens, M. and Uhlhaas, P. J. (2016) The 40-Hz auditory steady-state response in patients with schizophrenia: a meta-analysis. JAMA Psychiatry, 73(11), pp. 1145-1153. (doi: 10.1001/jamapsychiatry.2016.2619) (PMID:27732692)
Grent-'T-Jong, T. , Rivolta, D., Sauer, A., Grube, M., Singer, W., Wibral, M. and Uhlhaas, P. (2016) MEG-measured visually induced gamma-band oscillations in chronic schizophrenia: Evidence for impaired generation of rhythmic activity in ventral stream regions. Schizophrenia Research, 176(2-3), pp. 177-185. (doi: 10.1016/j.schres.2016.06.003) (PMID:27349815)
Tan, H.-R.M. , Gross, J. and Uhlhaas, P. (2016) MEG sensor and source measures of visually induced gamma-band oscillations are highly reliable. NeuroImage, 137, pp. 34-44. (doi: 10.1016/j.neuroimage.2016.05.006) (PMID:27153980) (PMCID:PMC5405052)
Millan, M. J. et al. (2016) Altering the course of schizophrenia: progress and perspectives. Nature Reviews Drug Discovery, 15(7), pp. 485-515. (doi: 10.1038/nrd.2016.28) (PMID:26939910)
Edwin Thanarajah, S., Han, C. E., Rotarska-Jagiela, A., Singer, W., Deichmann, R., Maurer, K., Kaiser, M. and Uhlhaas, P. J. (2016) Abnormal connectional fingerprint in schizophrenia: a novel network analysis of diffusion tensor imaging data. Frontiers in Psychiatry, 7, 114. (doi: 10.3389/fpsyt.2016.00114) (PMID:27445870) (PMCID:PMC4928135)
Schultze-Lutter, F., Debbané, M., Theodoridou, A., Wood, S. J., Raballo, A., Michel, C., Schmidt, S. J., Kindler, J., Ruhrmann, S. and Uhlhaas, P. J. (2016) Revisiting the basic symptom concept: toward translating risk symptoms for psychosis into neurobiological targets. Frontiers in Psychiatry, 7, 9. (doi: 10.3389/fpsyt.2016.00009) (PMID:26858660) (PMCID:PMC4729935)
Uhlhaas, P. J. and Roux, F. (2016) Thalamo-cortical interactions and synchronous oscillations in MEG data. In: Palva, S. (ed.) Multimodal Oscillation-based Connectivity Theory. Springer, pp. 69-86. ISBN 9783319322636 (doi: 10.1007/978-3-319-32265-0_5)
2015
Tan, H.-R.M. , Gross, J. and Uhlhaas, P.J. (2015) MEG-measured auditory steady-state oscillations show high test-retest reliability: a sensor and source-space analysis. NeuroImage, 122, pp. 417-426. (doi: 10.1016/j.neuroimage.2015.07.055) (PMID:6216274)
Rivolta, D., Heidegger, T., Scheller, B., Sauer, A., Schaum, M., Birkner, K., Singer, W., Wibral, M. and Uhlhaas, P. (2015) Ketamine dysregulates the amplitude and connectivity of high-frequency oscillations in cortical–subcortical networks in humans: evidence from resting-state magnetoencephalography-recordings. Schizophrenia Bulletin, 41(5), pp. 1105-1114. (doi: 10.1093/schbul/sbv051) (PMID:25987642)
Lim, S., Han, C. E., Uhlhaas, P. J. and Kaiser, M. (2015) Preferential detachment during human brain development: age- and sex-specific structural connectivity in Diffusion Tensor Imaging (DTI) data. Cerebral Cortex, 25(6), pp. 1477-1489. (doi: 10.1093/cercor/bht333) (PMID:24343892) (PMCID:PMC4428296)
Uhlhaas, P. J. (2015) Neural dynamics in mental disorders. World Psychiatry, 14(2), pp. 116-118. (doi: 10.1002/wps.20203) (PMID:26043320) (PMCID:PMC4471959)
Phillips, K. G. and Uhlhaas, P. J. (2015) Neural oscillations as a translational tool in schizophrenia research: rationale, paradigms and challenges. Journal of Psychopharmacology, 29(2), pp. 155-168. (doi: 10.1177/0269881114562093)
Uhlhaas, P. J. and Singer, W. (2015) Oscillations and neuronal dynamics in schizophrenia: the search for basic symptoms and translational opportunities. Biological Psychiatry, 77(12), pp. 1001-1009. (doi: 10.1016/j.biopsych.2014.11.019)
2014
Rivolta, D. et al. (2014) Source-Reconstruction of Event-Related Fields Reveals Hyperfunction and Hypofunction of Cortical Circuits in Antipsychotic-Naive, First-Episode Schizophrenia Patients during Mooney Face Processing. Journal of Neuroscience, 34(17), pp. 5909-5917. (doi: 10.1523/JNEUROSCI.3752-13.2014)
Gómez, C. et al. (2014) Reduced predictable information in brain signals in autism spectrum disorder. Frontiers in Neuroinformatics, 8(Art 9), (doi: 10.3389/fninf.2014.00009)
Klein, D., Rotarska-Jagiela, A., Genc, E., Sritharan, S., Mohr, H., Roux, F., Han, C.E., Kaiser, M., Singer, W. and Uhlhaas, P.J. (2014) Adolescent brain maturation and cortical folding: evidence for reductions in gyrification. PLoS ONE, 9(1), e84914. (doi: 10.1371/journal.pone.0084914) (PMID:24454765) (PMCID:PMC3893168)
Kuhn, J., Bodatsch, M., Sturm, V., Lenartz, D., Klosterkötter, J., Uhlhaas, P.J. , Winter, C. and Gruendler, T.O.J. (2014) Deep brain stimulation in schizophrenia. Activitas Nervosa Superior, 56(3), pp. 69-82.
Roux, F. and Uhlhaas, P. J. (2014) Working memory and neural oscillations: alpha–gamma versus theta–gamma codes for distinct WM information? Trends in Cognitive Sciences, 18(1), pp. 16-25. (doi: 10.1016/j.tics.2013.10.010)
2013
Roux, F., Wibral, M., Singer, W., Aru, J. and Uhlhaas, P.J. (2013) The phase of thalamic alpha activity modulates cortical gamma-band activity: evidence from resting-state MEG recordings. Journal of Neuroscience, 33(45), pp. 17827-17835. (doi: 10.1523/JNEUROSCI.5778-12.2013)
Sun, L., Castellanos, N., Grützner, C., Koethe, D., Rivolta, D., Wibral, M., Kranaster, L., Singer, W., Leweke, M.F. and Uhlhaas, P.J. (2013) Evidence for dysregulated high-frequency oscillations during sensory processing in medication-naïve, first episode schizophrenia. Schizophrenia Research, 150(2-3), pp. 519-525. (doi: 10.1016/j.schres.2013.08.023)
Uhlhaas, P. J. and Singer, W. (2013) High-frequency oscillations and the neurobiology of schizophrenia. Dialogues in Clinical Neuroscience, 15(3), pp. 301-313.
Konrad, K., Firk, C. and Uhlhaas, P.J. (2013) Brain development during adolescence: neuroscientific insights into this developmental period. Deutsches Ärzteblatt international, 110(25), pp. 425-31. (doi: 10.3238/arztebl.2013.0425)
Uhlhaas, P.J. (2013) Dysconnectivity, large-scale networks and neuronal dynamics in schizophrenia. Current Opinion in Neurobiology, 23(2), pp. 283-290. (doi: 10.1016/j.conb.2012.11.004)
Uhlhaas, P. J. , Roux, F. and Singer, W. (2013) Thalamocortical synchronization and cognition: implications for schizophrenia? Neuron, 77(6), pp. 997-999. (doi: 10.1016/j.neuron.2013.02.033)
Grützner, C., Wibral, M., Sun, L., Rivolta, D., Singer, W., Maurer, K. and Uhlhaas, P.J. (2013) Deficits in high- (>60 Hz) gamma-band oscillations during visual processing in schizophrenia. Frontiers in Human Neuroscience, 7(88), (doi: 10.3389/fnhum.2013.00088)
Konrad, K., Firk, C. and Uhlhaas, P. (2013) Temporal limitation and irreversibility of brain development reply. Deutsches Ärzteblatt international, 110(43), p. 733. (doi: 10.3238/arztebl.2013.0733b)
Tan, H.-R.M. , Lana, L. and Uhlhaas, P.J. (2013) High-frequency neural oscillations and visual processing deficits in schizophrenia. Frontiers in Psychology, 4(621), (doi: 10.3389/fpsyg.2013.00621)
2012
Uhlhaas, P.J. and Singer, W. (2012) Neuronal dynamics and neuropsychiatric disorders: toward a translational paradigm for dysfunctional large-scale networks. Neuron, 75(6), pp. 963-980. (doi: 10.1016/j.neuron.2012.09.004)
Roux, F., Wibral, M., Mohr, H.M., Singer, W. and Uhlhaas, P.J. (2012) Gamma-band activity in human prefrontal cortex codes for the number of relevant items maintained in working memory. Journal of Neuroscience, 32(36), pp. 12411-12420. (doi: 10.1523/JNEUROSCI.0421-12.2012)
Sun, L., Grutzner, C., Bolte, S., Wibral, M., Tozman, T., Schlitt, S., Poustka, F., Singer, W., Freitag, C.M. and Uhlhaas, P.J. (2012) Impaired gamma-band activity during perceptual organization in adults with autism spectrum disorders: evidence for dysfunctional network activity in frontal-posterior cortices. Journal of Neuroscience, 32(28), pp. 9563-9573. (doi: 10.1523/JNEUROSCI.1073-12.2012)
Knöchel, C. et al. (2012) Interhemispheric hypoconnectivity in schizophrenia: Fiber integrity and volume differences of the corpus callosum in patients and unaffected relatives. NeuroImage, 59(2), pp. 926-934. (doi: 10.1016/j.neuroimage.2011.07.088) (PMID:21964509)
2011
Kaiser, M., Uhlhaas, P.J. , Mohr, H., Rotarska-Jagiela, A., Han, C.E. and Echtermeyer, C. (2011) Integrating Temporal and Spatial Scales: Human Structural Network Motifs Across Age and Region of Interest Size. Frontiers in Neuroinformatics, 5(10), (doi: 10.3389/fninf.2011.00010)
Kuhn, J., Bodatsch, M., Sturm, V., Lenartz, D., Klosterkötter, J., Uhlhaas, P. , Winter, C. and Gründler, T. (2011) Tiefe Hirnstimulation bei der Schizophrenie. Fortschritte der Neurologie: Psychiatrie, 79(11), pp. 632-641. (doi: 10.1055/s-0031-1281733)
Luck, S.J., Mathalon, D.H., O'Donnell, B.F., Hämäläinen, M.S., Spencer, K.M., Javitt, D.C. and Uhlhaas, P.J. (2011) A Roadmap for the Development and Validation of Event-Related Potential Biomarkers in Schizophrenia Research. Biological Psychiatry, 70(1), pp. 28-34. (doi: 10.1016/j.biopsych.2010.09.021)
Uhlhaas, P.J. (2011) The Adolescent Brain: Implications for the Understanding, Pathophysiology, and Treatment of Schizophrenia. Schizophrenia Bulletin, 37(3), pp. 480-483. (doi: 10.1093/schbul/sbr025)
Uhlhaas, P.J. (2011) High-Frequency Oscillations in Schizophrenia. Clinical EEG and Neuroscience, 42(2), pp. 77-82. (doi: 10.1177/155005941104200208)
Uhlhaas, P.J. , Pipa, G., Neuenschwander, S., Wibral, M. and Singer, W. (2011) A new look at gamma? High- (>60 Hz) γ-band activity in cortical networks: Function, mechanisms and impairment. Progress in Biophysics and Molecular Biology, 105(1-2), pp. 14-28. (doi: 10.1016/j.pbiomolbio.2010.10.004)
Uhlhaas, P.J. and Singer, W. (2011) The Development of Neural Synchrony and Large-Scale Cortical Networks During Adolescence: Relevance for the Pathophysiology of Schizophrenia and Neurodevelopmental Hypothesis. Schizophrenia Bulletin, 37(3), pp. 514-523. (doi: 10.1093/schbul/sbr034)
2010
Uhlhaas, P. and Singer, W. (2010) Abnormal neural oscillations and synchrony in schizophrenia. Nature Reviews Neuroscience, 11(2), pp. 100-113. (doi: 10.1038/nrn2774) (PMID:20087360)
Grutzner, C., Uhlhaas, P.J. , Genc, E., Kohler, A., Singer, W. and Wibral, M. (2010) Neuroelectromagnetic Correlates of Perceptual Closure Processes. Journal of Neuroscience, 30(24), pp. 8342-8352. (doi: 10.1523/JNEUROSCI.5434-09.2010)
Oertel, V., Knochel, C., Rotarska-Jagiela, A., Schonmeyer, R., Lindner, M., van de Ven, V., Haenschel, C., Uhlhaas, P. , Maurer, K. and Linden, D.E.J. (2010) Reduced Laterality as a Trait Marker ofSchizophrenia--Evidence from Structural and Functional Neuroimaging. Journal of Neuroscience, 30(6), pp. 2289-2299. (doi: 10.1523/JNEUROSCI.4575-09.2010)
Uhlhaas, P.J. , Roux, F., Rodriguez, E., Rotarska-Jagiela, A. and Singer, W. (2010) Neural synchrony and the development of cortical networks. Trends in Cognitive Sciences, 14(2), pp. 72-80. (doi: 10.1016/j.tics.2009.12.002)
Wang, P., Havenith, M.N., Best, M., Gruetzner, C., Singer, W., Uhlhaas, P. and Nikolić, D. (2010) Time delays in the β/γ cycle operate on the level of individual neurons. NeuroReport, 21(11), pp. 746-750. (doi: 10.1097/WNR.0b013e32833ae9ed)
2009
Uhlhaas, P.J. , Roux, F., Singer, W., Haenschel, C., Sireteanu, R. and Rodriguez, E. (2009) The development of neural synchrony reflects late maturation and restructuring of functional networks in humans. Proceedings of the National Academy of Sciences of the United States of America, 106(24), pp. 9866-9871. (doi: 10.1073/pnas.0900390106)
Uhlhaas, P. (2009) Neural synchrony in cortical networks: history, concept and current status. Frontiers in Integrative Neuroscience, 3(17), (doi: 10.3389/neuro.07.017.2009)
2008
Uhlhaas, P.J. , Haenschel, C., Nikolic, D. and Singer, W. (2008) The Role of Oscillations and Synchrony in Cortical Networks and Their Putative Relevance for the Pathophysiology of Schizophrenia. Schizophrenia Bulletin, 34(5), pp. 927-943. (doi: 10.1093/schbul/sbn062)
Uhlhaas, P.J. , Pantel, J., Lanfermann, H., Prvulovic, D., Haenschel, C., Maurer, K. and Linden, D.E.J. (2008) Visual perceptual organization deficits in Alzheimer’s Dementia. Dementia and Geriatric Cognitive Disorders, 25(5), pp. 465-475. (doi: 10.1159/000125671)
Articles
Grent-'T-Jong, T. , Dheerendra, P. , Fusar-Poli, P., Gross, J. , Gumley, A. I. , Krishnadas, R. , Muckli, L. and Uhlhaas, P. (2024) Entrainment of neural oscillations during language processing in early-stage schizophrenia. NeuroImage: Clinical, (doi: 10.1016/j.nicl.2024.103695) (Early Online Publication)
Bianciardi, B., Mastek, H., Franka, M. and Uhlhaas, P. J. (2024) Effects of N-Methyl-D-aspartate receptor antagonists on gamma-band activity during auditory stimulation compared with electro/magneto-encephalographic data in schizophrenia and early-stage psychosis: a systematic review and perspective. Schizophrenia Bulletin, (doi: 10.1093/schbul/sbae090) (PMID:38934800) (Early Online Publication)
Smith, K. A. et al. (2024) Digital mental health for schizophrenia and other severe mental illnesses: an international consensus on current challenges and potential solutions. JMIR Mental Health, 11, e57155. (doi: 10.2196/57155) (PMID:38717799) (PMCID:PMC11112473)
Torous, J. et al. (2024) Digital health interventions for schizophrenia: setting standards for mental health. Schizophrenia Research, 267, pp. 392-395. (doi: 10.1016/j.schres.2024.04.013) (PMID:38640849)
Metzner, C., Dimulescu, C., Kamp, F., Fromm, S., Uhlhaas, P. J. and Obermayer, K. (2024) Exploring global and local processes underlying alterations in resting-state functional connectivity and dynamics in schizophrenia. Frontiers in Psychiatry, 15, 1352641. (doi: 10.3389/fpsyt.2024.1352641) (PMID:38414495) (PMCID:PMC10897003)
Allen, P. et al. (2024) Normative modeling of brain morphometry in clinical high risk for psychosis. JAMA Psychiatry, 81(1), pp. 77-88. (doi: 10.1001/jamapsychiatry.2023.3850) (PMID:37819650) (PMCID:PMC10568447)
Dheerendra, P. , Grent-'t-Jong, T. , Gajwani, R. , Gross, J. , Gumley, A. I. , Krishnadas, R. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2024) Intact mismatch negativity responses in clinical high-risk for psychosis and first-episode psychosis: evidence from source-reconstructed event-related fields and time-frequency data. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 9(1), pp. 121-131. (doi: 10.1016/j.bpsc.2023.09.006) (PMID:37778724)
Grent-'T-Jong, T. , Brickweddle, M., Metzner, C. and Uhlhaas, P. J. (2023) 40 Hz auditory steady state responses in schizophrenia: towards a mechanistic biomarker for circuit dysfunctions and early detection and diagnosis. Biological Psychiatry, 94(7), pp. 550-560. (doi: 10.1016/j.biopsych.2023.03.026) (PMID:37086914)
Hua, L. et al. (2023) Thalamo-cortical circuits during sensory attenuation in emerging psychosis: a combined magnetoencephalography and dynamic causal modelling study. npj Schizophrenia, 9, 25. (doi: 10.1038/s41537-023-00341-4) (PMID:37117187) (PMCID:PMC10147678)
Cooper, S. M., Fusar-Poli, P. and Uhlhaas, P. J. (2023) Characteristics and clinical correlates of risk symptoms in individuals at clinical high-risk for psychosis: a systematic review and meta-analysis. Schizophrenia Research, 254, pp. 54-61. (doi: 10.1016/j.schres.2023.02.011) (PMID:36801514)
Bianciardi, B., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Moelling, M., Schwannauer, M., Schultze-Lutter, F., Fracasso, A. and Uhlhaas, P. J. (2023) Investigating temporal and prosodic markers in clinical high-risk for psychosis participants using automated acoustic analysis. Early Intervention in Psychiatry, 17(3), pp. 327-330. (doi: 10.1111/eip.13357) (PMID:36205386)
Mancini, V., Rochas, V., Seeber, M., Grent-'t-Jong, T. , Rihs, T. A., Latrèche, C., Uhlhaas, P. J. , Michel, C. M. and Eliez, S. (2022) Oscillatory neural signatures of visual perception across developmental stages in individuals with 22q11.2 deletion syndrome. Biological Psychiatry, 92(5), pp. 407-418. (doi: 10.1016/j.biopsych.2022.02.961) (PMID:35550793)
Baldwin, H. et al. (2022) Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis. Translational Psychiatry, 12, 297. (doi: 10.1038/s41398-022-02057-y) (PMID:35882855) (PMCID:PMC9325730)
Haining, K. et al. (2022) Computerised cognitive training during early-stage psychosis improves cognitive deficits and gamma-band oscillations: a pilot study. Schizophrenia Research, 243, pp. 217-219. (doi: 10.1016/j.schres.2022.04.001) (PMID:35461044)
Haining, K., Gajwani, R. , Gross, J. , Gumley, A. I. , Ince, R. A.A. , Lawrie, S. M., Schultze-Lutter, F., Schwannauer, M. and Uhlhaas, P. J. (2022) Characterising cognitive heterogeneity in individuals at clinical high-risk for psychosis: a cluster analysis with clinical and functional outcome prediction. European Archives of Psychiatry and Clinical Neuroscience, 272(3), pp. 437-448. (doi: 10.1007/s00406-021-01315-2) (PMID:34401957)
Grent-'t-Jong, T. , Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F., Williams, S. R. and Uhlhaas, P. J. (2022) MR-spectroscopy of GABA and glutamate/glutamine concentrations in auditory cortex in clinical high-risk for psychosis individuals. Frontiers in Psychiatry, 13, 859322. (doi: 10.3389/fpsyt.2022.859322) (PMID:35422722) (PMCID:PMC9002006)
Mancini, V., Rochas, V., Seeber, M., Roehri, N., Rihs, T. A., Ferat, V., Schneider, M., Uhlhaas, P. J. , Eliez, S. and Michel, C. M. (2022) Aberrant developmental patterns of gamma-band response and long-range communication disruption in youths with 22q11.2 deletion syndrome. American Journal of Psychiatry, 179(3), pp. 204-215. (doi: 10.1176/appi.ajp.2021.21020190) (PMID:35236117)
Brunner, G., Gajwani, R. , Gross, J. , Gumley, A. I. , Krishnadas, R. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F., Fracasso, A. and Uhlhaas, P. J. (2022) Hippocampal structural alterations in early-stage psychosis: specificity and relationship to clinical outcomes. NeuroImage: Clinical, 35, 103087. (doi: 10.1016/j.nicl.2022.103087) (PMID:35780662) (PMCID:PMC9421451)
Kambeitz-Ilankovic, L., Rzayeva, U., Völkel, L., Wenzel, J., Weiske, J., Jessen, F., Reininghaus, U., Uhlhaas, P. J. , Alvarez-Jimenez, M. and Kambeitz, J. (2022) A systematic review of digital and face-to-face cognitive behavioral therapy for depression. npj Digital Medicine, 5, 144. (doi: 10.1038/s41746-022-00677-8) (PMID:36109583) (PMCID:PMC9476400)
Grent-'t-Jong, T. , Melloni, L. and Uhlhaas, P. J. (2021) Dissociation and brain rhythms: pitfalls and promises. Frontiers in Psychiatry, 12, 790372. (doi: 10.3389/fpsyt.2021.790372)
Haining, K., Karagiorgou, O., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2021) Prevalence and predictors of suicidality and non-suicidal self-harm among individuals at clinical high-risk for psychosis: results from a community-recruited sample. Early Intervention in Psychiatry, 15(5), pp. 1256-1265. (doi: 10.1111/eip.13075) (PMID:33372364) (PMCID:PMC8451831)
Grent-'T-Jong, T. , Gajwani, R. , Gross, J. , Gumley, A. I. , Krishnadas, R. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2021) 40-Hz auditory steady-state responses characterize circuit dysfunctions and predict clinical outcomes in clinical-high-risk participants: a magnetoencephalography study. Biological Psychiatry, 90(6), pp. 419-429. (doi: 10.1016/j.biopsych.2021.03.018) (PMID:34116790)
Bianciardi, B. and Uhlhaas, P. J. (2021) Do NMDA-R antagonists re-create patterns of spontaneous gamma-band activity in schizophrenia? A systematic review and perspective. Neuroscience and Biobehavioral Reviews, 124, pp. 308-323. (doi: 10.1016/j.neubiorev.2021.02.005) (PMID:33581223)
Haining, K., Brunner, G., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2021) The relationship between cognitive deficits and impaired short-term functional outcome in clinical high-risk for psychosis participants: a machine learning and modelling approach. Schizophrenia Research, 231, pp. 24-31. (doi: 10.1016/j.schres.2021.02.019) (PMID:33744682)
Cruz, G. , Grent-'t-Jong, T. , Krishnadas, R. , Palva, J. M. , Palva, S. and Uhlhaas, P. J. (2021) Long range temporal correlations (LRTCs) in MEG-data during emerging psychosis: relationship to symptoms, medication-status and clinical trajectory. NeuroImage: Clinical, 31, 102722. (doi: 10.1016/j.nicl.2021.102722) (PMID:34130193) (PMCID:PMC8209846)
Staines, L., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2021) Duration of basic and attenuated-psychotic symptoms in individuals at clinical high risk for psychosis: pattern of symptom onset and effects of duration on functioning and cognition. BMC Psychiatry, 21, 339. (doi: 10.1186/s12888-021-03267-2) (PMID:34233651) (PMCID:PMC8265048)
Zikidi, K., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F., Fracasso, A. and Uhlhaas, P. J. (2020) Grey-matter abnormalities in clinical high-risk participants for psychosis. Schizophrenia Research, 226, pp. 120-128. (doi: 10.1016/j.schres.2019.08.034) (PMID:31740178) (PMCID:PMC7774586)
Kocsis, A., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F., Grent-'t-Jong, T. and Uhlhaas, P. J. (2020) Altered autonomic function in individuals at clinical high risk for psychosis. Frontiers in Psychiatry, 11, 580503. (doi: 10.3389/fpsyt.2020.580503)
Hua, L., Recasens, M., Grent-'T-Jong, T. , Adams, R. A., Gross, J. and Uhlhaas, P. J. (2020) Investigating cortico-subcortical circuits during auditory sensory attenuation: a combined magnetoencephalographic and dynamic causal modelling study. Human Brain Mapping, 41(15), pp. 4419-4430. (doi: 10.1002/hbm.25134) (PMID:32662585) (PMCID:PMC7502827)
Grent-'T-Jong, T. , Gajwani, R. , Gross, J. , Gumley, A. I. , Krishnadas, R. , Lawrie, S., Schwannauer, M., Schultze-Lutte, F. and Uhlhaas, P. (2020) Association of magnetoencephalographically measured high-frequency oscillations in visual cortex with circuit dysfunctions in local and large-scale networks during emerging psychosis. JAMA Psychiatry, 77(8), pp. 852-862. (doi: 10.1001/jamapsychiatry.2020.0284) (PMID:32211834) (PMCID:PMC7097849)
Kostova, R. , Cecere, R., Thut, G. and Uhlhaas, P. J. (2020) Targeting cognition in schizophrenia through transcranial direct current stimulation: a systematic review and perspective. Schizophrenia Research, 220, pp. 300-310. (doi: 10.1016/j.schres.2020.03.002) (PMID:32204971)
Grent-'T-Jong, T. and Uhlhaas, P. J. (2020) The many facets of mismatch negativity. Biological Psychiatry, 87(8), pp. 695-696. (doi: 10.1016/j.biopsych.2020.01.022) (PMID:32216902)
Haining, K., Matrunola, C., Mitchell, L., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. J. (2020) Neuropsychological deficits in participants at clinical high risk for psychosis recruited from the community: relationships to functioning and clinical symptoms. Psychological Medicine, 50(1), pp. 77-85. (doi: 10.1017/S0033291718003975) (PMID:30862319)
Fusar-Poli, P., Sullivan, S. A., Shah, J. L. and Uhlhaas, P. J. (2019) Improving the detection of individuals at clinical risk for psychosis in the community, primary and secondary care: An integrated evidence-based approach. Frontiers in Psychiatry, 10, 774. (doi: 10.3389/fpsyt.2019.00774) (PMID:31708822) (PMCID:PMC6822017)
Uhlhaas, P. and Torous, J. (2019) Digital tools for youth mental health. npj Digital Medicine, 2, 104. (doi: 10.1038/s41746-019-0181-2) (PMID:31646184) (PMCID:PMC6802195)
Reilly, T., Mechelli, A., McGuire, P., Fusar-Poli, P. and Uhlhaas, P. J. (2019) E-Clinical high risk for psychosis: Viewpoint on potential of digital innovations for preventive psychiatry. JMIR Mental Health, 6(10), e14581. (doi: 10.2196/14581) (PMID:31584006)
Nikitova, N., Keane, B. P., Demmin, D., Silverstein, S. M. and Uhlhaas, P. J. (2019) The Audio-Visual Abnormalities Questionnaire (AVAQ): Development and validation of a new instrument for assessing anomalies in sensory perception in schizophrenia spectrum disorders. Schizophrenia Research, 209, pp. 227-233. (doi: 10.1016/j.schres.2019.03.016) (PMID:31182320)
McDonald, M., Christoforidou, E., Van Rijsbergen, N. , Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Schwannauer, M., Schultze-Lutter, F. and Uhlhaas, P. (2019) Using online-screening in the general population to detect participants at clinical high-risk for psychosis. Schizophrenia Bulletin, 45(3), pp. 600-609. (doi: 10.1093/schbul/sby069) (PMID:29889271) (PMCID:PMC6483579)
Mikanmaa, E., Grent-'t-Jong, T. , Hua, L., Recasens, M., Thune, H. and Uhlhaas, P. J. (2019) Towards a neurodynamical understanding of the prodrome in schizophrenia. NeuroImage, 190, pp. 144-153. (doi: 10.1016/j.neuroimage.2017.11.026) (PMID:29175199)
Sterzer, P., Adams, R. A., Fletcher, P., Frith, C., Lawrie, S. M., Muckli, L. , Petrovic, P., Uhlhaas, P. , Voss, M. and Corlett, P. R. (2018) The predictive coding account of psychosis. Biological Psychiatry, 84(9), pp. 634-643. (doi: 10.1016/j.biopsych.2018.05.015) (PMID:30007575) (PMCID:PMC6169400)
Grent-‘t-Jong, T. et al. (2018) Resting-state gamma-band power alterations in schizophrenia reveal functional E/I-balance abnormalities across illness-stages. eLife, 7, e37799. (doi: 10.7554/eLife.37799) (PMID:30260771) (PMCID:PMC6160226)
Recasens, M., Gross, J. and Uhlhaas, P. J. (2018) Low-frequency oscillatory correlates of auditory predictive processing in cortical-subcortical networks: a MEG-study. Scientific Reports, 8, 14007. (doi: 10.1038/s41598-018-32385-3) (PMID:30228366) (PMCID:PMC6143554)
Uhlhaas, P. J. , Grent-'t-Jong, T. and Gross, J. (2018) Magnetoencephalography and translational neuroscience in psychiatry. JAMA Psychiatry, 75(9), pp. 969-971. (doi: 10.1001/jamapsychiatry.2018.0775) (PMID:29799913)
Grent-'t-Jong, T. et al. (2018) Acute ketamine dysregulates task-related gamma-band oscillations in thalamo-cortical circuits in schizophrenia. Brain, 141(8), pp. 2511-2526. (doi: 10.1093/brain/awy175) (PMID:30020423) (PMCID:PMC6061682)
Sauer, A. et al. (2017) Impairment in predictive processes during auditory mismatch negativity in ScZ: evidence from event-related fields. Human Brain Mapping, 38(10), pp. 5082-5093. (doi: 10.1002/hbm.23716) (PMID:28677252)
Recasens, M. and Uhlhaas, P. J. (2017) Test-retest reliability of the magnetic mismatch negativity response to sound duration and omission deviants. NeuroImage, 157, pp. 184-195. (doi: 10.1016/j.neuroimage.2017.05.064) (PMID:28576412)
Uhlhaas, P. J. , Liddle, P., Linden, D. E.J., Nobre, A. C., Singh, K. D. and Gross, J. (2017) Magnetoencephalography as a tool in psychiatric research: current status and perspective. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2(3), pp. 235-244. (doi: 10.1016/j.bpsc.2017.01.005) (PMID:28424797) (PMCID:PMC5387180)
Pratt, J., Dawson, N., Morris, B. J. , Grent-'T-Jong, T. , Roux, F. and Uhlhaas, P. J. (2017) Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations: a unique window into the origins of ScZ? Schizophrenia Research, 180, pp. 4-12. (doi: 10.1016/j.schres.2016.05.013) (PMID:27317361)
Uhlhaas, P. J. , Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M. and Schwannauer, M. (2017) The Youth Mental Health Risk and Resilience Study (YouR-Study). BMC Psychiatry, 17, 43. (doi: 10.1186/s12888-017-1206-5) (PMID:28125984) (PMCID:PMC5270216)
Hirvonen, J., Wibral, M., Palva, J. M. , Singer, W., Uhlhaas, P. and Palva, S. (2017) Whole-brain source-reconstructed MEG-data reveal reduced long-range synchronization in chronic schizophrenia. eNeuro, 4(5), e0338-17.2. (doi: 10.1523/ENEURO.0338-17.2017) (PMID:29085902) (PMCID:PMC5659261)
Thuné, H., Recasens, M. and Uhlhaas, P. J. (2016) The 40-Hz auditory steady-state response in patients with schizophrenia: a meta-analysis. JAMA Psychiatry, 73(11), pp. 1145-1153. (doi: 10.1001/jamapsychiatry.2016.2619) (PMID:27732692)
Grent-'T-Jong, T. , Rivolta, D., Sauer, A., Grube, M., Singer, W., Wibral, M. and Uhlhaas, P. (2016) MEG-measured visually induced gamma-band oscillations in chronic schizophrenia: Evidence for impaired generation of rhythmic activity in ventral stream regions. Schizophrenia Research, 176(2-3), pp. 177-185. (doi: 10.1016/j.schres.2016.06.003) (PMID:27349815)
Tan, H.-R.M. , Gross, J. and Uhlhaas, P. (2016) MEG sensor and source measures of visually induced gamma-band oscillations are highly reliable. NeuroImage, 137, pp. 34-44. (doi: 10.1016/j.neuroimage.2016.05.006) (PMID:27153980) (PMCID:PMC5405052)
Millan, M. J. et al. (2016) Altering the course of schizophrenia: progress and perspectives. Nature Reviews Drug Discovery, 15(7), pp. 485-515. (doi: 10.1038/nrd.2016.28) (PMID:26939910)
Edwin Thanarajah, S., Han, C. E., Rotarska-Jagiela, A., Singer, W., Deichmann, R., Maurer, K., Kaiser, M. and Uhlhaas, P. J. (2016) Abnormal connectional fingerprint in schizophrenia: a novel network analysis of diffusion tensor imaging data. Frontiers in Psychiatry, 7, 114. (doi: 10.3389/fpsyt.2016.00114) (PMID:27445870) (PMCID:PMC4928135)
Schultze-Lutter, F., Debbané, M., Theodoridou, A., Wood, S. J., Raballo, A., Michel, C., Schmidt, S. J., Kindler, J., Ruhrmann, S. and Uhlhaas, P. J. (2016) Revisiting the basic symptom concept: toward translating risk symptoms for psychosis into neurobiological targets. Frontiers in Psychiatry, 7, 9. (doi: 10.3389/fpsyt.2016.00009) (PMID:26858660) (PMCID:PMC4729935)
Tan, H.-R.M. , Gross, J. and Uhlhaas, P.J. (2015) MEG-measured auditory steady-state oscillations show high test-retest reliability: a sensor and source-space analysis. NeuroImage, 122, pp. 417-426. (doi: 10.1016/j.neuroimage.2015.07.055) (PMID:6216274)
Rivolta, D., Heidegger, T., Scheller, B., Sauer, A., Schaum, M., Birkner, K., Singer, W., Wibral, M. and Uhlhaas, P. (2015) Ketamine dysregulates the amplitude and connectivity of high-frequency oscillations in cortical–subcortical networks in humans: evidence from resting-state magnetoencephalography-recordings. Schizophrenia Bulletin, 41(5), pp. 1105-1114. (doi: 10.1093/schbul/sbv051) (PMID:25987642)
Lim, S., Han, C. E., Uhlhaas, P. J. and Kaiser, M. (2015) Preferential detachment during human brain development: age- and sex-specific structural connectivity in Diffusion Tensor Imaging (DTI) data. Cerebral Cortex, 25(6), pp. 1477-1489. (doi: 10.1093/cercor/bht333) (PMID:24343892) (PMCID:PMC4428296)
Uhlhaas, P. J. (2015) Neural dynamics in mental disorders. World Psychiatry, 14(2), pp. 116-118. (doi: 10.1002/wps.20203) (PMID:26043320) (PMCID:PMC4471959)
Phillips, K. G. and Uhlhaas, P. J. (2015) Neural oscillations as a translational tool in schizophrenia research: rationale, paradigms and challenges. Journal of Psychopharmacology, 29(2), pp. 155-168. (doi: 10.1177/0269881114562093)
Uhlhaas, P. J. and Singer, W. (2015) Oscillations and neuronal dynamics in schizophrenia: the search for basic symptoms and translational opportunities. Biological Psychiatry, 77(12), pp. 1001-1009. (doi: 10.1016/j.biopsych.2014.11.019)
Rivolta, D. et al. (2014) Source-Reconstruction of Event-Related Fields Reveals Hyperfunction and Hypofunction of Cortical Circuits in Antipsychotic-Naive, First-Episode Schizophrenia Patients during Mooney Face Processing. Journal of Neuroscience, 34(17), pp. 5909-5917. (doi: 10.1523/JNEUROSCI.3752-13.2014)
Gómez, C. et al. (2014) Reduced predictable information in brain signals in autism spectrum disorder. Frontiers in Neuroinformatics, 8(Art 9), (doi: 10.3389/fninf.2014.00009)
Klein, D., Rotarska-Jagiela, A., Genc, E., Sritharan, S., Mohr, H., Roux, F., Han, C.E., Kaiser, M., Singer, W. and Uhlhaas, P.J. (2014) Adolescent brain maturation and cortical folding: evidence for reductions in gyrification. PLoS ONE, 9(1), e84914. (doi: 10.1371/journal.pone.0084914) (PMID:24454765) (PMCID:PMC3893168)
Kuhn, J., Bodatsch, M., Sturm, V., Lenartz, D., Klosterkötter, J., Uhlhaas, P.J. , Winter, C. and Gruendler, T.O.J. (2014) Deep brain stimulation in schizophrenia. Activitas Nervosa Superior, 56(3), pp. 69-82.
Roux, F. and Uhlhaas, P. J. (2014) Working memory and neural oscillations: alpha–gamma versus theta–gamma codes for distinct WM information? Trends in Cognitive Sciences, 18(1), pp. 16-25. (doi: 10.1016/j.tics.2013.10.010)
Roux, F., Wibral, M., Singer, W., Aru, J. and Uhlhaas, P.J. (2013) The phase of thalamic alpha activity modulates cortical gamma-band activity: evidence from resting-state MEG recordings. Journal of Neuroscience, 33(45), pp. 17827-17835. (doi: 10.1523/JNEUROSCI.5778-12.2013)
Sun, L., Castellanos, N., Grützner, C., Koethe, D., Rivolta, D., Wibral, M., Kranaster, L., Singer, W., Leweke, M.F. and Uhlhaas, P.J. (2013) Evidence for dysregulated high-frequency oscillations during sensory processing in medication-naïve, first episode schizophrenia. Schizophrenia Research, 150(2-3), pp. 519-525. (doi: 10.1016/j.schres.2013.08.023)
Uhlhaas, P. J. and Singer, W. (2013) High-frequency oscillations and the neurobiology of schizophrenia. Dialogues in Clinical Neuroscience, 15(3), pp. 301-313.
Konrad, K., Firk, C. and Uhlhaas, P.J. (2013) Brain development during adolescence: neuroscientific insights into this developmental period. Deutsches Ärzteblatt international, 110(25), pp. 425-31. (doi: 10.3238/arztebl.2013.0425)
Uhlhaas, P.J. (2013) Dysconnectivity, large-scale networks and neuronal dynamics in schizophrenia. Current Opinion in Neurobiology, 23(2), pp. 283-290. (doi: 10.1016/j.conb.2012.11.004)
Uhlhaas, P. J. , Roux, F. and Singer, W. (2013) Thalamocortical synchronization and cognition: implications for schizophrenia? Neuron, 77(6), pp. 997-999. (doi: 10.1016/j.neuron.2013.02.033)
Grützner, C., Wibral, M., Sun, L., Rivolta, D., Singer, W., Maurer, K. and Uhlhaas, P.J. (2013) Deficits in high- (>60 Hz) gamma-band oscillations during visual processing in schizophrenia. Frontiers in Human Neuroscience, 7(88), (doi: 10.3389/fnhum.2013.00088)
Konrad, K., Firk, C. and Uhlhaas, P. (2013) Temporal limitation and irreversibility of brain development reply. Deutsches Ärzteblatt international, 110(43), p. 733. (doi: 10.3238/arztebl.2013.0733b)
Tan, H.-R.M. , Lana, L. and Uhlhaas, P.J. (2013) High-frequency neural oscillations and visual processing deficits in schizophrenia. Frontiers in Psychology, 4(621), (doi: 10.3389/fpsyg.2013.00621)
Uhlhaas, P.J. and Singer, W. (2012) Neuronal dynamics and neuropsychiatric disorders: toward a translational paradigm for dysfunctional large-scale networks. Neuron, 75(6), pp. 963-980. (doi: 10.1016/j.neuron.2012.09.004)
Roux, F., Wibral, M., Mohr, H.M., Singer, W. and Uhlhaas, P.J. (2012) Gamma-band activity in human prefrontal cortex codes for the number of relevant items maintained in working memory. Journal of Neuroscience, 32(36), pp. 12411-12420. (doi: 10.1523/JNEUROSCI.0421-12.2012)
Sun, L., Grutzner, C., Bolte, S., Wibral, M., Tozman, T., Schlitt, S., Poustka, F., Singer, W., Freitag, C.M. and Uhlhaas, P.J. (2012) Impaired gamma-band activity during perceptual organization in adults with autism spectrum disorders: evidence for dysfunctional network activity in frontal-posterior cortices. Journal of Neuroscience, 32(28), pp. 9563-9573. (doi: 10.1523/JNEUROSCI.1073-12.2012)
Knöchel, C. et al. (2012) Interhemispheric hypoconnectivity in schizophrenia: Fiber integrity and volume differences of the corpus callosum in patients and unaffected relatives. NeuroImage, 59(2), pp. 926-934. (doi: 10.1016/j.neuroimage.2011.07.088) (PMID:21964509)
Kaiser, M., Uhlhaas, P.J. , Mohr, H., Rotarska-Jagiela, A., Han, C.E. and Echtermeyer, C. (2011) Integrating Temporal and Spatial Scales: Human Structural Network Motifs Across Age and Region of Interest Size. Frontiers in Neuroinformatics, 5(10), (doi: 10.3389/fninf.2011.00010)
Kuhn, J., Bodatsch, M., Sturm, V., Lenartz, D., Klosterkötter, J., Uhlhaas, P. , Winter, C. and Gründler, T. (2011) Tiefe Hirnstimulation bei der Schizophrenie. Fortschritte der Neurologie: Psychiatrie, 79(11), pp. 632-641. (doi: 10.1055/s-0031-1281733)
Luck, S.J., Mathalon, D.H., O'Donnell, B.F., Hämäläinen, M.S., Spencer, K.M., Javitt, D.C. and Uhlhaas, P.J. (2011) A Roadmap for the Development and Validation of Event-Related Potential Biomarkers in Schizophrenia Research. Biological Psychiatry, 70(1), pp. 28-34. (doi: 10.1016/j.biopsych.2010.09.021)
Uhlhaas, P.J. (2011) The Adolescent Brain: Implications for the Understanding, Pathophysiology, and Treatment of Schizophrenia. Schizophrenia Bulletin, 37(3), pp. 480-483. (doi: 10.1093/schbul/sbr025)
Uhlhaas, P.J. (2011) High-Frequency Oscillations in Schizophrenia. Clinical EEG and Neuroscience, 42(2), pp. 77-82. (doi: 10.1177/155005941104200208)
Uhlhaas, P.J. , Pipa, G., Neuenschwander, S., Wibral, M. and Singer, W. (2011) A new look at gamma? High- (>60 Hz) γ-band activity in cortical networks: Function, mechanisms and impairment. Progress in Biophysics and Molecular Biology, 105(1-2), pp. 14-28. (doi: 10.1016/j.pbiomolbio.2010.10.004)
Uhlhaas, P.J. and Singer, W. (2011) The Development of Neural Synchrony and Large-Scale Cortical Networks During Adolescence: Relevance for the Pathophysiology of Schizophrenia and Neurodevelopmental Hypothesis. Schizophrenia Bulletin, 37(3), pp. 514-523. (doi: 10.1093/schbul/sbr034)
Uhlhaas, P. and Singer, W. (2010) Abnormal neural oscillations and synchrony in schizophrenia. Nature Reviews Neuroscience, 11(2), pp. 100-113. (doi: 10.1038/nrn2774) (PMID:20087360)
Grutzner, C., Uhlhaas, P.J. , Genc, E., Kohler, A., Singer, W. and Wibral, M. (2010) Neuroelectromagnetic Correlates of Perceptual Closure Processes. Journal of Neuroscience, 30(24), pp. 8342-8352. (doi: 10.1523/JNEUROSCI.5434-09.2010)
Oertel, V., Knochel, C., Rotarska-Jagiela, A., Schonmeyer, R., Lindner, M., van de Ven, V., Haenschel, C., Uhlhaas, P. , Maurer, K. and Linden, D.E.J. (2010) Reduced Laterality as a Trait Marker ofSchizophrenia--Evidence from Structural and Functional Neuroimaging. Journal of Neuroscience, 30(6), pp. 2289-2299. (doi: 10.1523/JNEUROSCI.4575-09.2010)
Uhlhaas, P.J. , Roux, F., Rodriguez, E., Rotarska-Jagiela, A. and Singer, W. (2010) Neural synchrony and the development of cortical networks. Trends in Cognitive Sciences, 14(2), pp. 72-80. (doi: 10.1016/j.tics.2009.12.002)
Wang, P., Havenith, M.N., Best, M., Gruetzner, C., Singer, W., Uhlhaas, P. and Nikolić, D. (2010) Time delays in the β/γ cycle operate on the level of individual neurons. NeuroReport, 21(11), pp. 746-750. (doi: 10.1097/WNR.0b013e32833ae9ed)
Uhlhaas, P.J. , Roux, F., Singer, W., Haenschel, C., Sireteanu, R. and Rodriguez, E. (2009) The development of neural synchrony reflects late maturation and restructuring of functional networks in humans. Proceedings of the National Academy of Sciences of the United States of America, 106(24), pp. 9866-9871. (doi: 10.1073/pnas.0900390106)
Uhlhaas, P. (2009) Neural synchrony in cortical networks: history, concept and current status. Frontiers in Integrative Neuroscience, 3(17), (doi: 10.3389/neuro.07.017.2009)
Uhlhaas, P.J. , Haenschel, C., Nikolic, D. and Singer, W. (2008) The Role of Oscillations and Synchrony in Cortical Networks and Their Putative Relevance for the Pathophysiology of Schizophrenia. Schizophrenia Bulletin, 34(5), pp. 927-943. (doi: 10.1093/schbul/sbn062)
Uhlhaas, P.J. , Pantel, J., Lanfermann, H., Prvulovic, D., Haenschel, C., Maurer, K. and Linden, D.E.J. (2008) Visual perceptual organization deficits in Alzheimer’s Dementia. Dementia and Geriatric Cognitive Disorders, 25(5), pp. 465-475. (doi: 10.1159/000125671)
Book Sections
Uhlhaas, P. J. and Roux, F. (2016) Thalamo-cortical interactions and synchronous oscillations in MEG data. In: Palva, S. (ed.) Multimodal Oscillation-based Connectivity Theory. Springer, pp. 69-86. ISBN 9783319322636 (doi: 10.1007/978-3-319-32265-0_5)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- State of the art MEG-TRIUX-neo for advancing multi-modal neuroimaging techniques in Scotland
Wellcome Trust
2020 - 2025
- Developing an Online-Screening Tool for Detecting Early-Stage Psychosis
Wellcome Trust
2020 - 2022
- Identifying Neural Signatures of Auditory-Predictive Processing in Schizophrenia: A Multi-Modal Imaging Approach
Medical Research Council
2019 - 2022
- PREDAMEG
European Commission
2017 - 2018
- From attachment to psychopathology: Affective dysregulation and neurodevelopmental disorder in young people at-risk of severe and enduring mental illness
NHS Greater Glasgow and Clyde
2016 - 2018
- Using Magnetoencephalography to Investigate Aberrant Neural Synchrony in Prodromal Schizophrenia: A Translational Biomarker Approach
Medical Research Council
2014 - 2018
Supervision
Supervised Postgraduate Student
- Gina Brunner (Postgraduate)
Research Assistants
- Gina Brunner (Research Assistant)
- Pradeep Dheerendra (Research Associate)
- Tineke Grent-‘t-Jong (Affiliate)
Visiting Collaborator
- Marc Recasens (External Collaborator)