2021

Neves, K. B. , Morris, H., Alves-Lopes, R., Muir, K. W. , Moreton, F., Delles, C. , Montezano, A. C. and Touyz, R. M. (2021) Peripheral arteriopathy caused by Notch3 gain-of-function mutation involves ER and oxidative stress and blunting of NO∕sGC∕cGMP pathway. Clinical Science, 135(6), pp. 753-773. (doi: 10.1042/CS20201412) (PMID:33681964)

Moreton, F. C., Cullen, B. , Dickie, D. A. , Lopez Gonzalez, R., Santosh, C., Delles, C. and Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28(1), pp. 220-228. (doi: 10.1111/ene.14534) (PMID:32931073)

2020

Bivard, A. et al. (2020) Comparing mismatch strategies for patients being considered for ischemic stroke tenecteplase trials. International Journal of Stroke, 15(5), pp. 507-515. (doi: 10.1177/1747493019884529) (PMID:31684841)

2019

Neves, K. B. et al. (2019) ER stress and Rho kinase activation underlie the vasculopathy of CADASIL. JCI Insight, 4(23), e131344. (doi: 10.1172/jci.insight.131344) (PMID:31647781) (PMCID:PMC6962020)

Kelleher, J. et al. (2019) Patient-specific iPSC model of a genetic vascular dementia syndrome reveals failure of mural cells to stabilize capillary structures. Stem Cell Reports, 13(5), pp. 817-831. (doi: 10.1016/j.stemcr.2019.10.004) (PMID:31680059) (PMCID:PMC6893064)

Kalladka, D., Sinden, J., McLean, J., Moreton, F. C., Huang, X. and Muir, K. W. (2019) Increased deep grey matter functional connectivity of poststroke hNSC implanted ipsilesional putamen. Journal of Neurology, Neurosurgery and Psychiatry, 90(8), pp. 959-960. (doi: 10.1136/jnnp-2018-319022) (PMID:30530567)

Al-Shahi Salman, R. et al. (2019) Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial. Lancet Neurology, 18(7), pp. 643-652. (doi: 10.1016/S1474-4422(19)30184-X) (PMID:31129065)

Al-Shahi Salman, R. et al. (2019) Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial. Lancet, 393(10191), pp. 2613-2623. (doi: 10.1016/S0140-6736(19)30840-2) (PMID:31128924) (PMCID:PMC6617509)

2018

Moreton, F. C., Cullen, B. , Delles, C. , Santosh, C., Lopez Gonzalez, R., Dani, K. and Muir, K. W. (2018) Vasoreactivity in CADASIL: comparison to structural MRI and neuropsychology. Journal of Cerebral Blood Flow and Metabolism, 38(6), pp. 1085-1095. (doi: 10.1177/0271678X17710375) (PMID:28537106)

Al-Shahi Salman, R. et al. (2018) The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial. Trials, 19, 162. (doi: 10.1186/s13063-018-2542-6) (PMID:29506580) (PMCID:PMC5838871)

2017

Huang, X., Kalladka, D., Cheripelli, B. K., Moreton, F. C. and Muir, K. W. (2017) The impact of CT perfusion threshold on predicted viable and nonviable tissue volumes in acute ischaemic stroke. Journal of Neuroimaging, 27(6), pp. 602-606. (doi: 10.1111/jon.12442) (PMID:28414895)

Moreton, F. C., Düring, M., Phan, T., Srikanth, V., Beare, R., Huang, X., Jouvent, E., Chabriat, H., Dichgans, M. and Muir, K. W. (2017) Arterial branching and basal ganglia lacunes: a study in pure small vessel disease. European Stroke Journal, 2(3), pp. 264-271. (doi: 10.1177/2396987317718450)

Bivard, A. et al. (2017) Tenecteplase in ischemic stroke offers improved recanalization: analysis of 2 trials. Neurology, 89(1), pp. 62-67. (doi: 10.1212/WNL.0000000000004062) (PMID:28576782)

Bivard, A. et al. (2017) Impact of computed tomography perfusion imaging on the response to tenecteplase in ischemic stroke: analysis of two randomized controlled trials. Circulation, 135(5), pp. 440-448. (doi: 10.1161/CIRCULATIONAHA.116.022582) (PMID:27965285)

Dani, K. A., Moreton, F. C., Santosh, C., Lopez, R., Brennan, D., Schwarzbauer, C., Goutcher, C., O’Hare, K., Macrae, I. M. and Muir, K. W. (2017) Oxygen challenge magnetic resonance imaging in healthy human volunteers. Journal of Cerebral Blood Flow and Metabolism, 37(1), pp. 366-376. (doi: 10.1177/0271678x15627827) (PMID:26787107) (PMCID:PMC5363753)

2016

El Tawil, S., Cheripelli, B., Huang, X., Moreton, F., Kalladka, D., MacDougal, N. J.J., McVerry, F. and Muir, K. W. (2016) How many stroke patients might be eligible for mechanical thrombectomy? European Stroke Journal, 1(4), pp. 264-271. (doi: 10.1177/2396987316667176)

Cullen, B. , Moreton, F. C., Stringer, M. S., Krishnadas, R. , Kalladka, D., López-González, M. R., Santosh, C., Schwarzbauer, C. and Muir, K. W. (2016) Resting state connectivity and cognitive performance in adults with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Journal of Cerebral Blood Flow and Metabolism, 36(5), pp. 981-991. (doi: 10.1177/0271678X16636395) (PMID:26929239)

Østergaard, L., Engedal, T. S., Moreton, F., Hansen, M. B., Wardlaw, J. M., Dalkara, T., Markus, H. S. and Muir, K. W. (2016) Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline. Journal of Cerebral Blood Flow and Metabolism, 36(2), pp. 302-325. (doi: 10.1177/0271678X15606723) (PMID:26661176) (PMCID:PMC4759673)

Moreton, F. C., Dani, K. A., Goutcher, C., O'Hare, K. and Muir, K. W. (2016) Respiratory challenge MRI: practical aspects. NeuroImage: Clinical, 11, pp. 667-677. (doi: 10.1016/j.nicl.2016.05.003)

2015

Moreton, F., Santosh, C., McArthur, K. and Muir, K. (2015) Cerebral hyperperfusion on arterial spin labeling MRI during CADASIL migrainous encephalopathy. Neurology, 85(24), pp. 2177-2179. (doi: 10.1212/WNL.0000000000002214) (PMID:26567267)

Huang, X., Moreton, F., Kalladka, D., Cheripelli, B. K., Macisaac, R., Tait, R. C. and Muir, K. (2015) Coagulation and fibrinolytic activity of tenecteplase and alteplase in acute ischemic stroke. Stroke, 46(12), pp. 3543-3546. (doi: 10.1161/strokeaha.115.011290) (PMID:26514192)

Huang, X., Cheripelli, B. K., Lloyd, S. M. , Kalladka, D., Moreton, F. C., Siddiqui, A., Ford, I. and Muir, K. W. (2015) Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST): phase 2 randomised clinical trial. Lancet Neurology, 14(4), pp. 368-376. (doi: 10.1016/S1474-4422(15)70017-7) (PMID:25726502)

Wollenweber, F.A. et al. (2015) Cysteine-sparing CADASIL mutations in NOTCH3 show proaggregatory properties in vitro. Stroke, 46(3), pp. 786-792. (doi: 10.1161/STROKEAHA.114.007472) (PMID:25604251)

2014

Moreton, F., Razvi, S., Davidson, R. and Muir, K. (2014) Changing clinical patterns and increasing prevalence in CADASIL. Acta Neurologica Scandinavica, 130(3), pp. 197-203. (doi: 10.1111/ane.12266)

2007

Moreton, F.C., McCormick, M. and Muir, K.W. (2007) Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study. Stroke, 38(2), pp. 407-410. (doi: 10.1161/01.STR.0000254487.73282.4d)

Articles

Neves, K. B. , Morris, H., Alves-Lopes, R., Muir, K. W. , Moreton, F., Delles, C. , Montezano, A. C. and Touyz, R. M. (2021) Peripheral arteriopathy caused by Notch3 gain-of-function mutation involves ER and oxidative stress and blunting of NO∕sGC∕cGMP pathway. Clinical Science, 135(6), pp. 753-773. (doi: 10.1042/CS20201412) (PMID:33681964)

Moreton, F. C., Cullen, B. , Dickie, D. A. , Lopez Gonzalez, R., Santosh, C., Delles, C. and Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28(1), pp. 220-228. (doi: 10.1111/ene.14534) (PMID:32931073)

Bivard, A. et al. (2020) Comparing mismatch strategies for patients being considered for ischemic stroke tenecteplase trials. International Journal of Stroke, 15(5), pp. 507-515. (doi: 10.1177/1747493019884529) (PMID:31684841)

Neves, K. B. et al. (2019) ER stress and Rho kinase activation underlie the vasculopathy of CADASIL. JCI Insight, 4(23), e131344. (doi: 10.1172/jci.insight.131344) (PMID:31647781) (PMCID:PMC6962020)

Kelleher, J. et al. (2019) Patient-specific iPSC model of a genetic vascular dementia syndrome reveals failure of mural cells to stabilize capillary structures. Stem Cell Reports, 13(5), pp. 817-831. (doi: 10.1016/j.stemcr.2019.10.004) (PMID:31680059) (PMCID:PMC6893064)

Kalladka, D., Sinden, J., McLean, J., Moreton, F. C., Huang, X. and Muir, K. W. (2019) Increased deep grey matter functional connectivity of poststroke hNSC implanted ipsilesional putamen. Journal of Neurology, Neurosurgery and Psychiatry, 90(8), pp. 959-960. (doi: 10.1136/jnnp-2018-319022) (PMID:30530567)

Al-Shahi Salman, R. et al. (2019) Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial. Lancet Neurology, 18(7), pp. 643-652. (doi: 10.1016/S1474-4422(19)30184-X) (PMID:31129065)

Al-Shahi Salman, R. et al. (2019) Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial. Lancet, 393(10191), pp. 2613-2623. (doi: 10.1016/S0140-6736(19)30840-2) (PMID:31128924) (PMCID:PMC6617509)

Moreton, F. C., Cullen, B. , Delles, C. , Santosh, C., Lopez Gonzalez, R., Dani, K. and Muir, K. W. (2018) Vasoreactivity in CADASIL: comparison to structural MRI and neuropsychology. Journal of Cerebral Blood Flow and Metabolism, 38(6), pp. 1085-1095. (doi: 10.1177/0271678X17710375) (PMID:28537106)

Al-Shahi Salman, R. et al. (2018) The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial. Trials, 19, 162. (doi: 10.1186/s13063-018-2542-6) (PMID:29506580) (PMCID:PMC5838871)

Huang, X., Kalladka, D., Cheripelli, B. K., Moreton, F. C. and Muir, K. W. (2017) The impact of CT perfusion threshold on predicted viable and nonviable tissue volumes in acute ischaemic stroke. Journal of Neuroimaging, 27(6), pp. 602-606. (doi: 10.1111/jon.12442) (PMID:28414895)

Moreton, F. C., Düring, M., Phan, T., Srikanth, V., Beare, R., Huang, X., Jouvent, E., Chabriat, H., Dichgans, M. and Muir, K. W. (2017) Arterial branching and basal ganglia lacunes: a study in pure small vessel disease. European Stroke Journal, 2(3), pp. 264-271. (doi: 10.1177/2396987317718450)

Bivard, A. et al. (2017) Tenecteplase in ischemic stroke offers improved recanalization: analysis of 2 trials. Neurology, 89(1), pp. 62-67. (doi: 10.1212/WNL.0000000000004062) (PMID:28576782)

Bivard, A. et al. (2017) Impact of computed tomography perfusion imaging on the response to tenecteplase in ischemic stroke: analysis of two randomized controlled trials. Circulation, 135(5), pp. 440-448. (doi: 10.1161/CIRCULATIONAHA.116.022582) (PMID:27965285)

Dani, K. A., Moreton, F. C., Santosh, C., Lopez, R., Brennan, D., Schwarzbauer, C., Goutcher, C., O’Hare, K., Macrae, I. M. and Muir, K. W. (2017) Oxygen challenge magnetic resonance imaging in healthy human volunteers. Journal of Cerebral Blood Flow and Metabolism, 37(1), pp. 366-376. (doi: 10.1177/0271678x15627827) (PMID:26787107) (PMCID:PMC5363753)

El Tawil, S., Cheripelli, B., Huang, X., Moreton, F., Kalladka, D., MacDougal, N. J.J., McVerry, F. and Muir, K. W. (2016) How many stroke patients might be eligible for mechanical thrombectomy? European Stroke Journal, 1(4), pp. 264-271. (doi: 10.1177/2396987316667176)

Cullen, B. , Moreton, F. C., Stringer, M. S., Krishnadas, R. , Kalladka, D., López-González, M. R., Santosh, C., Schwarzbauer, C. and Muir, K. W. (2016) Resting state connectivity and cognitive performance in adults with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Journal of Cerebral Blood Flow and Metabolism, 36(5), pp. 981-991. (doi: 10.1177/0271678X16636395) (PMID:26929239)

Østergaard, L., Engedal, T. S., Moreton, F., Hansen, M. B., Wardlaw, J. M., Dalkara, T., Markus, H. S. and Muir, K. W. (2016) Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline. Journal of Cerebral Blood Flow and Metabolism, 36(2), pp. 302-325. (doi: 10.1177/0271678X15606723) (PMID:26661176) (PMCID:PMC4759673)

Moreton, F. C., Dani, K. A., Goutcher, C., O'Hare, K. and Muir, K. W. (2016) Respiratory challenge MRI: practical aspects. NeuroImage: Clinical, 11, pp. 667-677. (doi: 10.1016/j.nicl.2016.05.003)

Moreton, F., Santosh, C., McArthur, K. and Muir, K. (2015) Cerebral hyperperfusion on arterial spin labeling MRI during CADASIL migrainous encephalopathy. Neurology, 85(24), pp. 2177-2179. (doi: 10.1212/WNL.0000000000002214) (PMID:26567267)

Huang, X., Moreton, F., Kalladka, D., Cheripelli, B. K., Macisaac, R., Tait, R. C. and Muir, K. (2015) Coagulation and fibrinolytic activity of tenecteplase and alteplase in acute ischemic stroke. Stroke, 46(12), pp. 3543-3546. (doi: 10.1161/strokeaha.115.011290) (PMID:26514192)

Huang, X., Cheripelli, B. K., Lloyd, S. M. , Kalladka, D., Moreton, F. C., Siddiqui, A., Ford, I. and Muir, K. W. (2015) Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST): phase 2 randomised clinical trial. Lancet Neurology, 14(4), pp. 368-376. (doi: 10.1016/S1474-4422(15)70017-7) (PMID:25726502)

Wollenweber, F.A. et al. (2015) Cysteine-sparing CADASIL mutations in NOTCH3 show proaggregatory properties in vitro. Stroke, 46(3), pp. 786-792. (doi: 10.1161/STROKEAHA.114.007472) (PMID:25604251)

Moreton, F., Razvi, S., Davidson, R. and Muir, K. (2014) Changing clinical patterns and increasing prevalence in CADASIL. Acta Neurologica Scandinavica, 130(3), pp. 197-203. (doi: 10.1111/ane.12266)

Moreton, F.C., McCormick, M. and Muir, K.W. (2007) Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study. Stroke, 38(2), pp. 407-410. (doi: 10.1161/01.STR.0000254487.73282.4d)