Dr Antoine Vallatos
- Senior Lecturer in MRI Physics & Translational Imaging Biomarker Development (Centre for Neuroscience)
telephone:
01413304490
email:
Antoine.Vallatos@glasgow.ac.uk
Wellcome Surgical Institute, University of Glasgow, Garscube campus, Bearsden, United Kingdom, G61 1QH G61 1QH
https://orcid.org/0000-0002-5202-056XResearch interests
My research programme aims at streamlining imaging biomarkers to the clinics by methodically addressing the challenges at the interface between on one side MRI physics & imaging and on the other biology & medicine. My work lies at the intersection of these fields, covering the development of novel MRI modalities and applied biomarkers, and the systematic validation of both the MRI measure and the biomarker.
Publications
2024
Mintoft, A., Vallatos, A. and Robertson, N. J. (2024) Mesenchymal Stromal Cell therapy for Hypoxic Ischemic Encephalopathy: future directions for combination therapy with hypothermia and/or melatonin. Seminars in Perinatology, 48(5), 151929. (doi: 10.1016/j.semperi.2024.151929) (PMID:38902120)
2023
Paterson, S., Vallatos, A. , Rodgers, J. and Holmes, W. M. (2023) Application of diffusion weighted multiple boli ASL to a murine model of human African trypanosomiasis. Scientific Reports, 13, 8684. (doi: 10.1038/s41598-023-34665-z) (PMID:37248398) (PMCID:PMC10227057)
2022
Quick, S. et al. (2022) Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model. Acta Neuropathologica, 144(2), pp. 283-303. (doi: 10.1007/s00401-022-02441-4) (PMID:35635573) (PMCID:PMC9288385)
2021
Vallatos, A. et al. (2021) Adaptive manufacturing for healthcare during the COVID-19 emergency and beyond. Frontiers in Medical Technology, 3, 702526. (doi: 10.3389/fmedt.2021.702526) (PMID:35047941) (PMCID:PMC8757720)
Al-Mubarak, H. F.I., Vallatos, A. and Holmes, W. M. (2021) Impact of turbulence-induced asymmetric propagators on the accuracy of phase-contrast velocimetry. Journal of Magnetic Resonance, 325, 106929. (doi: 10.1016/j.jmr.2021.106929) (PMID:33713991)
Al-mubarak, H., Vallatos, A. , Gallagher, L., Birch, J. , Chalmers, A.J. and Holmes, W.M. (2021) Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma. Magnetic resonance imaging, 85, pp. 121-127. (doi: 10.1016/j.mri.2021.10.030) (PMID:34687852)
2019
Al-Mubarak, H., Vallatos, A. , Gallagher, L., Birch, J. , Gilmour, L., Foster, J., Chalmers, A.J. and Holmes, W.M. (2019) Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model. Journal of Neuroscience Methods, 326, 108372. (doi: 10.1016/j.jneumeth.2019.108372) (PMID:31348965)
Vallatos, A. , Al-Mubarak, H.F.I., Birch, J.L. , Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M. and Chalmers, A.J. (2019) Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region. Journal of Magnetic Resonance Imaging, 50(2), pp. 529-540. (doi: 10.1002/jmri.26580) (PMID:30569620)
Arroja, M.M.C., Reid, E. , Roy, L.A., Vallatos, A.V. , Holmes, W.M. , Nicklin, S.A. , Work, L.M. and McCabe, C. (2019) Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion. Scientific Reports, 9, 3154. (doi: 10.1038/s41598-019-39102-8) (PMID:30816157) (PMCID:PMC6395816)
2018
Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)
Vallatos, A. , Al Mubarak, H. F.I., Mullin, J. M. and Holmes, W. M. (2018) Accuracy of phase-contrast velocimetry in systems with skewed intravoxel velocity distributions. Journal of Magnetic Resonance, 296, pp. 121-129. (doi: 10.1016/j.jmr.2018.09.002) (PMID:30245475)
Vallatos, A. , Shukla, M. N., Mullin, J. M., Phoenix, V. R. and Holmes, W. M. (2018) The effect of displacement distribution asymmetry on the accuracy of phase-shift velocimetry in porous media. Microporous and Mesoporous Materials, 269, pp. 130-133. (doi: 10.1016/j.micromeso.2017.11.048)
Holmes, W. M. , Vallatos, A. , Gilmour, L. and Chalmers, A. J. (2018) Multiple boli arterial spin labelling for high signal-to-noise rodent brain perfusion imaging. Magnetic Resonance in Medicine, 79(2), pp. 1020-1030. (doi: 10.1002/mrm.26706) (PMID:28516482)
2016
Shukla, M. N., Vallatos, A. , Phoenix, V. R. and Holmes, W. M. (2016) Accurate phase-shift velocimetry in rock. Journal of Magnetic Resonance, 267, pp. 43-53. (doi: 10.1016/j.jmr.2016.04.006) (PMID:27111139)
2015
Vallatos, A. , Kirsch, R.M., Williams, R.A., Hammond, R.B., Jia, X., Bröckel, U. and Britton, M.M. (2015) Probing composition and molecular mobility in thin spherical films using nuclear magnetic resonance measurements of diffusion. Industrial and Engineering Chemistry Research, 54(26), pp. 6825-6830. (doi: 10.1021/acs.iecr.5b01700)
2013
Vallatos, A. , Evans, R., Thompson, B. W., Taylor, A. F. and Britton, M. M. (2013) Chemical patterns in translating vortices: Inter- and intra-cellular mixing effects. Chaos: An Interdisciplinary Journal of Nonlinear Science, 23(2), 023115. (doi: 10.1063/1.4807619)
2012
Vallatos, A. , Wilson, M. C.T., Taylor, A. F. and Britton, M. M. (2012) Characterising stationary and translating vortex flow using magnetic resonance. Europhysics Letters, 99(6), p. 68001. (doi: 10.1209/0295-5075/99/68001)
Articles
Mintoft, A., Vallatos, A. and Robertson, N. J. (2024) Mesenchymal Stromal Cell therapy for Hypoxic Ischemic Encephalopathy: future directions for combination therapy with hypothermia and/or melatonin. Seminars in Perinatology, 48(5), 151929. (doi: 10.1016/j.semperi.2024.151929) (PMID:38902120)
Paterson, S., Vallatos, A. , Rodgers, J. and Holmes, W. M. (2023) Application of diffusion weighted multiple boli ASL to a murine model of human African trypanosomiasis. Scientific Reports, 13, 8684. (doi: 10.1038/s41598-023-34665-z) (PMID:37248398) (PMCID:PMC10227057)
Quick, S. et al. (2022) Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model. Acta Neuropathologica, 144(2), pp. 283-303. (doi: 10.1007/s00401-022-02441-4) (PMID:35635573) (PMCID:PMC9288385)
Vallatos, A. et al. (2021) Adaptive manufacturing for healthcare during the COVID-19 emergency and beyond. Frontiers in Medical Technology, 3, 702526. (doi: 10.3389/fmedt.2021.702526) (PMID:35047941) (PMCID:PMC8757720)
Al-Mubarak, H. F.I., Vallatos, A. and Holmes, W. M. (2021) Impact of turbulence-induced asymmetric propagators on the accuracy of phase-contrast velocimetry. Journal of Magnetic Resonance, 325, 106929. (doi: 10.1016/j.jmr.2021.106929) (PMID:33713991)
Al-mubarak, H., Vallatos, A. , Gallagher, L., Birch, J. , Chalmers, A.J. and Holmes, W.M. (2021) Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma. Magnetic resonance imaging, 85, pp. 121-127. (doi: 10.1016/j.mri.2021.10.030) (PMID:34687852)
Al-Mubarak, H., Vallatos, A. , Gallagher, L., Birch, J. , Gilmour, L., Foster, J., Chalmers, A.J. and Holmes, W.M. (2019) Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model. Journal of Neuroscience Methods, 326, 108372. (doi: 10.1016/j.jneumeth.2019.108372) (PMID:31348965)
Vallatos, A. , Al-Mubarak, H.F.I., Birch, J.L. , Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M. and Chalmers, A.J. (2019) Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region. Journal of Magnetic Resonance Imaging, 50(2), pp. 529-540. (doi: 10.1002/jmri.26580) (PMID:30569620)
Arroja, M.M.C., Reid, E. , Roy, L.A., Vallatos, A.V. , Holmes, W.M. , Nicklin, S.A. , Work, L.M. and McCabe, C. (2019) Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion. Scientific Reports, 9, 3154. (doi: 10.1038/s41598-019-39102-8) (PMID:30816157) (PMCID:PMC6395816)
Birch, J. L. et al. (2018) A novel small-molecule inhibitor of MRCK prevents radiation-driven invasion in glioblastoma. Cancer Research, 78(22), pp. 6509-6522. (doi: 10.1158/0008-5472.CAN-18-1697) (PMID:30279244)
Vallatos, A. , Al Mubarak, H. F.I., Mullin, J. M. and Holmes, W. M. (2018) Accuracy of phase-contrast velocimetry in systems with skewed intravoxel velocity distributions. Journal of Magnetic Resonance, 296, pp. 121-129. (doi: 10.1016/j.jmr.2018.09.002) (PMID:30245475)
Vallatos, A. , Shukla, M. N., Mullin, J. M., Phoenix, V. R. and Holmes, W. M. (2018) The effect of displacement distribution asymmetry on the accuracy of phase-shift velocimetry in porous media. Microporous and Mesoporous Materials, 269, pp. 130-133. (doi: 10.1016/j.micromeso.2017.11.048)
Holmes, W. M. , Vallatos, A. , Gilmour, L. and Chalmers, A. J. (2018) Multiple boli arterial spin labelling for high signal-to-noise rodent brain perfusion imaging. Magnetic Resonance in Medicine, 79(2), pp. 1020-1030. (doi: 10.1002/mrm.26706) (PMID:28516482)
Shukla, M. N., Vallatos, A. , Phoenix, V. R. and Holmes, W. M. (2016) Accurate phase-shift velocimetry in rock. Journal of Magnetic Resonance, 267, pp. 43-53. (doi: 10.1016/j.jmr.2016.04.006) (PMID:27111139)
Vallatos, A. , Kirsch, R.M., Williams, R.A., Hammond, R.B., Jia, X., Bröckel, U. and Britton, M.M. (2015) Probing composition and molecular mobility in thin spherical films using nuclear magnetic resonance measurements of diffusion. Industrial and Engineering Chemistry Research, 54(26), pp. 6825-6830. (doi: 10.1021/acs.iecr.5b01700)
Vallatos, A. , Evans, R., Thompson, B. W., Taylor, A. F. and Britton, M. M. (2013) Chemical patterns in translating vortices: Inter- and intra-cellular mixing effects. Chaos: An Interdisciplinary Journal of Nonlinear Science, 23(2), 023115. (doi: 10.1063/1.4807619)
Vallatos, A. , Wilson, M. C.T., Taylor, A. F. and Britton, M. M. (2012) Characterising stationary and translating vortex flow using magnetic resonance. Europhysics Letters, 99(6), p. 68001. (doi: 10.1209/0295-5075/99/68001)
