2023

Alghanimy, A., Martin, C., Gallagher, L. and Holmes, W. M. (2023) The effect of a novel AQP4 facilitator, TGN-073, on glymphatic transport captured by diffusion MRI and DCE-MRI. PLoS ONE, 18(3), e0282955. (doi: 10.1371/journal.pone.0282955) (PMID:36920936) (PMCID:PMC10016657)

2022

Murphy, G., Jayasekera, G. , Mullin, J., Gallagher, L. and Welsh, D. J. (2022) Exploring the failing right ventricle in pulmonary hypertension by cardiac magnetic resonance: an in vivo study utilizing Macitentan. Pulmonary Circulation, 12(3), e12124. (doi: 10.1002/pul2.12124) (PMID:36092794) (PMCID:PMC9438403)

2021

Alshuhri, M. S. , Gallagher, L., Work, L. and Holmes, W. (2021) Direct imaging of glymphatic flow using H217O MRI. JCI Insight, 6(10), e141159. (doi: 10.1172/jci.insight.141159) (PMID:33857020)

Al-mubarak, H., Vallatos, A. , Gallagher, L., Birch, J. , Chalmers, A.J. and Holmes, W.M. (2021) Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma. Magnetic resonance imaging, 85, pp. 121-127. (doi: 10.1016/j.mri.2021.10.030) (PMID:34687852)

2020

Alshuhri, M. S. , Gallagher, L., McCabe, C. and Holmes, W. M. (2020) Change in CSF dynamics responsible for ICP elevation after ischemic stroke in rats: a new mechanism for unexplained END? Translational Stroke Research, 11, pp. 310-318. (doi: 10.1007/s12975-019-00719-6)

2019

Al-Mubarak, H., Vallatos, A. , Gallagher, L., Birch, J. , Gilmour, L., Foster, J., Chalmers, A.J. and Holmes, W.M. (2019) Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model. Journal of Neuroscience Methods, 326, 108372. (doi: 10.1016/j.jneumeth.2019.108372) (PMID:31348965)

Vallatos, A. , Al-Mubarak, H.F.I., Birch, J.L. , Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M. and Chalmers, A.J. (2019) Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region. Journal of Magnetic Resonance Imaging, 50(2), pp. 529-540. (doi: 10.1002/jmri.26580) (PMID:30569620)

2018

Merrifield, G. D., Brydges, N. M., Hall, L., Mullin, J., Gallagher, L., Pizzi, R. and Holmes, W. M. (2018) Measures of cardiac function in Theraphosidae spiders using in vivo magnetic resonance imaging. Physiological Entomology, 43(3), pp. 207-213. (doi: 10.1111/phen.12245)

2017

Merrifield, G. D., Mullin, J., Gallagher, L., Tucker, C., Jansen, M. A., Denvir, M. and Holmes, W. M. (2017) Rapid and recoverable in vivo magnetic resonance imaging of the adult zebrafish at 7T. Magnetic Resonance Imaging, 37, pp. 9-15. (doi: 10.1016/j.mri.2016.10.013) (PMID:27751860) (PMCID:PMC5344283)

2014

Wetterling, F., Gallagher, L., Mullin, J., Holmes, W. M. , McCabe, C. , Macrae, I. M. and Fagan, A. J. (2014) Sodium-23 magnetic resonance imaging has potential for improving penumbra detection but not for estimating stroke onset time. Journal of Cerebral Blood Flow and Metabolism, 35(1), pp. 103-110. (doi: 10.1038/jcbfm.2014.174)

2012

Holmes, W.M. , Lopez-Gonzalez, M.R., Gallagher, L., Deuchar, G., Macrae, I. and Santosh, C. (2012) Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR in Biomedicine, 25(2), pp. 295-304. (doi: 10.1002/nbm.1748)

Wetterling, F., Gallagher, L., Macrae, I.M., Junge, S. and Fagan, A.J. (2012) Regional and temporal variations in tissue sodium concentration during the acute stroke phase. Magnetic Resonance in Medicine, 67(3), pp. 740-749. (doi: 10.1002/mrm.23031)

2011

Robertson, C. A., McCabe, C. , Gallagher, L., Lopez Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1788-1798. (doi: 10.1038/jcbfm.2011.67)

Robertson, C. A., McCabe, C. , Gallagher, L., Lopez-Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography. Journal of Cerebral Blood Flow and Metabolism, 31, pp. 1778-1787. (doi: 10.1038/jcbfm.2011.66)

2010

McCabe, C. , Gallagher, L., Macrae, I.M., Gsell, W., Graham, D. and Dominiczak, A.F. (2010) Response to letter by Yao (Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats). Stroke, 41(4), E198-E199. (doi: 10.1161/STROKEAHA.109.575704)

Wetterling, F., Tabbert, M., Junge, S., Gallagher, L., Macrae, I.M. and Fagan, A.J. (2010) A double-tuned1H/23Na dual resonator system for tissue sodium concentration measurements in the rat brain via Na-MRI. Physics in Medicine and Biology, 55(24), pp. 7681-7695. (doi: 10.1088/0031-9155/55/24/019)

2009

McCabe, C. , Gallagher, L., Gsell, W., Graham, D. , Dominiczak, A. F. and Macrae, I. M. (2009) Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. Stroke, 40(12), pp. 3864-3868. (doi: 10.1161/STROKEAHA.109.559021)

2008

Santosh, C. et al. (2008) Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. Journal of Cerebral Blood Flow and Metabolism, 28(10), pp. 1742-1753. (doi: 10.1038/jcbfm.2008.56)

Lecrux, C., McCabe, C. , Weir, C.J., Gallagher, L., Mullin, J., Touzani, O., Muir, K. , Lees, K.R. and Macrae, I.M. (2008) Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats. Stroke, 39(2), pp. 448-454. (doi: 10.1161/STROKEAHA.107.492934)

Fagan, A., Mullin, J., Gallagher, L., Hadley, D., Macrae, I. and Condon, B. (2008) Serial postmortem relaxometry in the normal rat brain and following stroke. Journal of Magnetic Resonance Imaging, 27(3), pp. 469-475.

Articles

Alghanimy, A., Martin, C., Gallagher, L. and Holmes, W. M. (2023) The effect of a novel AQP4 facilitator, TGN-073, on glymphatic transport captured by diffusion MRI and DCE-MRI. PLoS ONE, 18(3), e0282955. (doi: 10.1371/journal.pone.0282955) (PMID:36920936) (PMCID:PMC10016657)

Murphy, G., Jayasekera, G. , Mullin, J., Gallagher, L. and Welsh, D. J. (2022) Exploring the failing right ventricle in pulmonary hypertension by cardiac magnetic resonance: an in vivo study utilizing Macitentan. Pulmonary Circulation, 12(3), e12124. (doi: 10.1002/pul2.12124) (PMID:36092794) (PMCID:PMC9438403)

Alshuhri, M. S. , Gallagher, L., Work, L. and Holmes, W. (2021) Direct imaging of glymphatic flow using H217O MRI. JCI Insight, 6(10), e141159. (doi: 10.1172/jci.insight.141159) (PMID:33857020)

Al-mubarak, H., Vallatos, A. , Gallagher, L., Birch, J. , Chalmers, A.J. and Holmes, W.M. (2021) Evaluating potential of multi-parametric MRI using co-registered histology: Application to a mouse model of glioblastoma. Magnetic resonance imaging, 85, pp. 121-127. (doi: 10.1016/j.mri.2021.10.030) (PMID:34687852)

Alshuhri, M. S. , Gallagher, L., McCabe, C. and Holmes, W. M. (2020) Change in CSF dynamics responsible for ICP elevation after ischemic stroke in rats: a new mechanism for unexplained END? Translational Stroke Research, 11, pp. 310-318. (doi: 10.1007/s12975-019-00719-6)

Al-Mubarak, H., Vallatos, A. , Gallagher, L., Birch, J. , Gilmour, L., Foster, J., Chalmers, A.J. and Holmes, W.M. (2019) Stacked in-plane histology for quantitative validation of non-invasive imaging biomarkers: application to an infiltrative brain tumour model. Journal of Neuroscience Methods, 326, 108372. (doi: 10.1016/j.jneumeth.2019.108372) (PMID:31348965)

Vallatos, A. , Al-Mubarak, H.F.I., Birch, J.L. , Gallagher, L., Mullin, J.M., Gilmour, L., Holmes, W.M. and Chalmers, A.J. (2019) Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region. Journal of Magnetic Resonance Imaging, 50(2), pp. 529-540. (doi: 10.1002/jmri.26580) (PMID:30569620)

Merrifield, G. D., Brydges, N. M., Hall, L., Mullin, J., Gallagher, L., Pizzi, R. and Holmes, W. M. (2018) Measures of cardiac function in Theraphosidae spiders using in vivo magnetic resonance imaging. Physiological Entomology, 43(3), pp. 207-213. (doi: 10.1111/phen.12245)

Merrifield, G. D., Mullin, J., Gallagher, L., Tucker, C., Jansen, M. A., Denvir, M. and Holmes, W. M. (2017) Rapid and recoverable in vivo magnetic resonance imaging of the adult zebrafish at 7T. Magnetic Resonance Imaging, 37, pp. 9-15. (doi: 10.1016/j.mri.2016.10.013) (PMID:27751860) (PMCID:PMC5344283)

Wetterling, F., Gallagher, L., Mullin, J., Holmes, W. M. , McCabe, C. , Macrae, I. M. and Fagan, A. J. (2014) Sodium-23 magnetic resonance imaging has potential for improving penumbra detection but not for estimating stroke onset time. Journal of Cerebral Blood Flow and Metabolism, 35(1), pp. 103-110. (doi: 10.1038/jcbfm.2014.174)

Holmes, W.M. , Lopez-Gonzalez, M.R., Gallagher, L., Deuchar, G., Macrae, I. and Santosh, C. (2012) Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR in Biomedicine, 25(2), pp. 295-304. (doi: 10.1002/nbm.1748)

Wetterling, F., Gallagher, L., Macrae, I.M., Junge, S. and Fagan, A.J. (2012) Regional and temporal variations in tissue sodium concentration during the acute stroke phase. Magnetic Resonance in Medicine, 67(3), pp. 740-749. (doi: 10.1002/mrm.23031)

Robertson, C. A., McCabe, C. , Gallagher, L., Lopez Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 2. Validation based on the consequences of reperfusion. Journal of Cerebral Blood Flow and Metabolism, 31(8), pp. 1788-1798. (doi: 10.1038/jcbfm.2011.67)

Robertson, C. A., McCabe, C. , Gallagher, L., Lopez-Gonzalez, M. d., Holmes, W. M. , Condon, B., Muir, K. W. , Santosh, C. and Macrae, I. M. (2011) Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography. Journal of Cerebral Blood Flow and Metabolism, 31, pp. 1778-1787. (doi: 10.1038/jcbfm.2011.66)

McCabe, C. , Gallagher, L., Macrae, I.M., Gsell, W., Graham, D. and Dominiczak, A.F. (2010) Response to letter by Yao (Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats). Stroke, 41(4), E198-E199. (doi: 10.1161/STROKEAHA.109.575704)

Wetterling, F., Tabbert, M., Junge, S., Gallagher, L., Macrae, I.M. and Fagan, A.J. (2010) A double-tuned1H/23Na dual resonator system for tissue sodium concentration measurements in the rat brain via Na-MRI. Physics in Medicine and Biology, 55(24), pp. 7681-7695. (doi: 10.1088/0031-9155/55/24/019)

McCabe, C. , Gallagher, L., Gsell, W., Graham, D. , Dominiczak, A. F. and Macrae, I. M. (2009) Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. Stroke, 40(12), pp. 3864-3868. (doi: 10.1161/STROKEAHA.109.559021)

Santosh, C. et al. (2008) Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra. Journal of Cerebral Blood Flow and Metabolism, 28(10), pp. 1742-1753. (doi: 10.1038/jcbfm.2008.56)

Lecrux, C., McCabe, C. , Weir, C.J., Gallagher, L., Mullin, J., Touzani, O., Muir, K. , Lees, K.R. and Macrae, I.M. (2008) Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats. Stroke, 39(2), pp. 448-454. (doi: 10.1161/STROKEAHA.107.492934)

Fagan, A., Mullin, J., Gallagher, L., Hadley, D., Macrae, I. and Condon, B. (2008) Serial postmortem relaxometry in the normal rat brain and following stroke. Journal of Magnetic Resonance Imaging, 27(3), pp. 469-475.