Dr William Sands
- Research Associate (Molecular Biosciences)
Publications
2020
Wilkie, S. E., Mulvey, L., Sands, W., Marcu, D. E., Carter, R. N., Morton, N. M., Hine, C., Mitchell, J. R. and Selman, C. (2020) Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice. GeroScience, 42, pp. 801-812. (doi: 10.1007/s11357-020-00168-2) (PMID:32162209) (PMCID:PMC7205779)
2017
Mulvey, L., Sands, W. A., Salin, K., Carr, A. E. and Selman, C. (2017) Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice. Molecular and Cellular Endocrinology, 455, pp. 41-53. (doi: 10.1016/j.mce.2016.09.001) (PMID:27597651)
Sands, W. A., Page, M. M. and Selman, C. (2017) Proteostasis and ageing: insights from long-lived mutant mice. Journal of Physiology, 595(20), pp. 6383-6390. (doi: 10.1113/JP274334) (PMID:28718225) (PMCID:PMC5638872)
2013
Sands, W.A., Copland, M. and Wheadon, H. (2013) Targeting self-renewal pathways in myeloid malignancies. Cell Communication and Signaling, 11(33), (doi: 10.1186/1478-811X-11-33)
2012
McManus, F., Sands, W., Diver, L., MacKenzie, S. M. , Fraser, R., Davies, E. and Connell, J. M. (2012) APEX1 regulation of aldosterone synthase gene transcription is disrupted by a common polymorphism in humans. Circulation Research, 111(2), pp. 212-219. (doi: 10.1161/CIRCRESAHA.111.262931)
Sands, W. A., Woolson, H. D., Yarwood, S. J. and Palmer, T. M. (2012) Exchange protein directly activated by cyclic AMP-1-regulated recruitment of CCAAT/enhancer-binding proteins to the suppressor of cytokine signaling-3 promoter. Methods in Molecular Biology, 809, pp. 201-214. (doi: 10.1007/978-1-61779-376-9_14)
2011
Edward, M., Quinn, J.A. and Sands, W. (2011) Keratinocytes stimulate fibroblast hyaluronan synthesis through the release of stratifin: A possible role in the suppression of scar tissue formation. Wound Repair and Regeneration, 19(3), pp. 379-386. (doi: 10.1111/j.1524-475X.2011.00678.x)
Stevens, K.K., McQuarrie, E.P., Sands, W., Hillyard, D.Z., Patel, R.K., Mark, P.B. and Jardine, A.G. (2011) Fibroblast growth factor 23 predicts left ventricular mass and induces cell adhesion molecule formation. International Journal of Nephrology, 2011(297070), pp. 1-6. (doi: 10.4061/2011/297070)
2010
Safhi, M. M. A., Rutherford, C., Ledent, C., Sands, W. A. and Palmer, T. M. (2010) Priming of signal transducer and activator of transcription proteins for cytokine-triggered polyubiquitylation and degradation by the A2a adenosine receptor. Molecular Pharmacology, 77(6), pp. 968-978. (doi: 10.1124/mol.109.062455)
Sandilands, G. P., Wilson, M., Huser, C. , Jolly, L., Sands, W. A. and McSharry, C. (2010) Were monocytes responsible for initiating the cytokine storm in the TGN1412 clinical trial tragedy? Clinical and Experimental Immunology, 162(3), pp. 516-527. (doi: 10.1111/j.1365-2249.2010.04264.x)
2008
Yarwood, S.J., Borland, G., Sands, W.A. and Palmer, T.M. (2008) Identification of CCAAT/Enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene. Journal of Biological Chemistry, 283(11), pp. 6843-6853. (doi: 10.1074/jbc.M710342200)
2006
Sands, W.A., Woolson, H.D., Milne, G.R., Rutherford, C. and Palmer, T.M. (2006) Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells. Molecular and Cellular Biology, 26(17), pp. 6333-6346.
1999
Piedrafita, D. et al. (1999) Regulation of macrophage IL-12 synthesis by Leishmania phosphoglycans. European Journal of Immunology, 29(1), pp. 235-244. (doi: 10.1002/(SICI)1521-4141(199901)29:01<235::AID-IMMU235>3.0.CO;2-S) (PMID:9933105)
1998
Huang, F.-P., Xu, D., Esfandiari, E.-O., Sands, W., Wei, X.-q. and Liew, F. Y. (1998) Cutting edge: Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated interleukin-12 synthesis, strong Th1 responses and enhanced nitric oxide production. Journal of Immunology, 160(9), pp. 4143-4147. (PMID:9574511)
1994
Sands, W. A., Bulut, V., Severn, A., Xu, D. and Liew, F. Y. (1994) Inhibition of nitric oxide synthesis by interleukin-4 may involve inhibiting the activation of protein kinase C epsilon. European Journal of Immunology, 24(10), pp. 2345-2350. (doi: 10.1002/eji.1830241013) (PMID:7523136)
Articles
Wilkie, S. E., Mulvey, L., Sands, W., Marcu, D. E., Carter, R. N., Morton, N. M., Hine, C., Mitchell, J. R. and Selman, C. (2020) Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice. GeroScience, 42, pp. 801-812. (doi: 10.1007/s11357-020-00168-2) (PMID:32162209) (PMCID:PMC7205779)
Mulvey, L., Sands, W. A., Salin, K., Carr, A. E. and Selman, C. (2017) Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice. Molecular and Cellular Endocrinology, 455, pp. 41-53. (doi: 10.1016/j.mce.2016.09.001) (PMID:27597651)
Sands, W. A., Page, M. M. and Selman, C. (2017) Proteostasis and ageing: insights from long-lived mutant mice. Journal of Physiology, 595(20), pp. 6383-6390. (doi: 10.1113/JP274334) (PMID:28718225) (PMCID:PMC5638872)
Sands, W.A., Copland, M. and Wheadon, H. (2013) Targeting self-renewal pathways in myeloid malignancies. Cell Communication and Signaling, 11(33), (doi: 10.1186/1478-811X-11-33)
McManus, F., Sands, W., Diver, L., MacKenzie, S. M. , Fraser, R., Davies, E. and Connell, J. M. (2012) APEX1 regulation of aldosterone synthase gene transcription is disrupted by a common polymorphism in humans. Circulation Research, 111(2), pp. 212-219. (doi: 10.1161/CIRCRESAHA.111.262931)
Sands, W. A., Woolson, H. D., Yarwood, S. J. and Palmer, T. M. (2012) Exchange protein directly activated by cyclic AMP-1-regulated recruitment of CCAAT/enhancer-binding proteins to the suppressor of cytokine signaling-3 promoter. Methods in Molecular Biology, 809, pp. 201-214. (doi: 10.1007/978-1-61779-376-9_14)
Edward, M., Quinn, J.A. and Sands, W. (2011) Keratinocytes stimulate fibroblast hyaluronan synthesis through the release of stratifin: A possible role in the suppression of scar tissue formation. Wound Repair and Regeneration, 19(3), pp. 379-386. (doi: 10.1111/j.1524-475X.2011.00678.x)
Stevens, K.K., McQuarrie, E.P., Sands, W., Hillyard, D.Z., Patel, R.K., Mark, P.B. and Jardine, A.G. (2011) Fibroblast growth factor 23 predicts left ventricular mass and induces cell adhesion molecule formation. International Journal of Nephrology, 2011(297070), pp. 1-6. (doi: 10.4061/2011/297070)
Safhi, M. M. A., Rutherford, C., Ledent, C., Sands, W. A. and Palmer, T. M. (2010) Priming of signal transducer and activator of transcription proteins for cytokine-triggered polyubiquitylation and degradation by the A2a adenosine receptor. Molecular Pharmacology, 77(6), pp. 968-978. (doi: 10.1124/mol.109.062455)
Sandilands, G. P., Wilson, M., Huser, C. , Jolly, L., Sands, W. A. and McSharry, C. (2010) Were monocytes responsible for initiating the cytokine storm in the TGN1412 clinical trial tragedy? Clinical and Experimental Immunology, 162(3), pp. 516-527. (doi: 10.1111/j.1365-2249.2010.04264.x)
Yarwood, S.J., Borland, G., Sands, W.A. and Palmer, T.M. (2008) Identification of CCAAT/Enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene. Journal of Biological Chemistry, 283(11), pp. 6843-6853. (doi: 10.1074/jbc.M710342200)
Sands, W.A., Woolson, H.D., Milne, G.R., Rutherford, C. and Palmer, T.M. (2006) Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells. Molecular and Cellular Biology, 26(17), pp. 6333-6346.
Piedrafita, D. et al. (1999) Regulation of macrophage IL-12 synthesis by Leishmania phosphoglycans. European Journal of Immunology, 29(1), pp. 235-244. (doi: 10.1002/(SICI)1521-4141(199901)29:01<235::AID-IMMU235>3.0.CO;2-S) (PMID:9933105)
Huang, F.-P., Xu, D., Esfandiari, E.-O., Sands, W., Wei, X.-q. and Liew, F. Y. (1998) Cutting edge: Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated interleukin-12 synthesis, strong Th1 responses and enhanced nitric oxide production. Journal of Immunology, 160(9), pp. 4143-4147. (PMID:9574511)
Sands, W. A., Bulut, V., Severn, A., Xu, D. and Liew, F. Y. (1994) Inhibition of nitric oxide synthesis by interleukin-4 may involve inhibiting the activation of protein kinase C epsilon. European Journal of Immunology, 24(10), pp. 2345-2350. (doi: 10.1002/eji.1830241013) (PMID:7523136)