Dr Martin Boocock
- Honorary Research Fellow (School of Molecular Biosciences)
email:
Martin.Boocock@glasgow.ac.uk
R504 Level 5, Institute of MC&SB, Bower Building, Glasgow G12 8QQ
Publications
2024
Cadden, G. M., Schloetel, J.-G., McKenzie, G. , Boocock, M. R., Magennis, S. W. and Stark, W. M. (2024) Direct observation of subunit rotation during DNA strand exchange by serine recombinases. Nature Communications, 15, 10407. (doi: 10.1038/s41467-024-54531-4) (PMID:39613732) (PMCID:PMC11607074)
2023
Montaño, S. P., Rowland, S.-J., Fuller, J. R., Burke, M. E., MacDonald, A. I., Boocock, M. R., Stark, W. M. and Rice, P. A. (2023) Structural basis for topological regulation of Tn3 resolvase. Nucleic Acids Research, 51(3), pp. 1001-1018. (doi: 10.1093/nar/gkac733) (PMID:36100255) (PMCID:PMC9943657)
2020
Rowland, S.-J., Boocock, M. R., Burke, M. E., Rice, P. A. and Stark, W. M. (2020) The protein-protein interactions required for assembly of the Tn3 resolution synapse. Molecular Microbiology, 114(6), pp. 952-965. (doi: 10.1111/mmi.14579) (PMID:33405333)
2018
Trejo, C. S., Rock, R. S., Stark, W. M. , Boocock, M. R. and Rice, P. A. (2018) Snapshots of a molecular swivel in action. Nucleic Acids Research, 46(10), pp. 5286-5296. (doi: 10.1093/nar/gkx1309) (PMID:29315406) (PMCID:PMC6007550)
2013
Keenholtz, R.A., Mouw, K.W., Boocock, M.R., Li, N.-S., Piccirilli, J.A. and Rice, P.A. (2013) Arginine as a general acid catalyst in serine recombinase-mediated DNA cleavage. Journal of Biological Chemistry, 288(40), pp. 29206-29214. (doi: 10.1074/jbc.M113.508028)
Misiura, A., Pigli, Y.Z., Boyle-Vavra, S., Daum, R.S., Boocock, M.R. and Rice, P.A. (2013) Roles of two large serine recombinases in mobilizing the methicillin-resistance cassette SCCmec. Molecular Microbiology, 88(6), pp. 1218-1229. (doi: 10.1111/mmi.12253)
Boocock, M.R. and Rice, P.A. (2013) A proposed mechanism for IS607-family serine transposases. Mobile DNA, 4(24), (doi: 10.1186/1759-8753-4-24)
2011
Keenholtz, R.A., Rowland, S.-J., Boocock, M.R., Stark, W.M. and Rice, P.A. (2011) Structural Basis for Catalytic Activation of a Serine Recombinase. Structure, 19(6), pp. 799-809. (doi: 10.1016/j.str.2011.03.017)
Stark, W.M. , Boocock, M.R., Olorunniji, F.J. and Rowland, S.-J. (2011) Intermediates in serine recombinase-mediated site-specific recombination. Biochemical Society Transactions, 39(2), pp. 617-622. (doi: 10.1042/BST0390617)
2010
Mouw, K.W., Steiner, A.M., Ghirlando, R., Li, N.-S., Rowland, S.-J., Boocock, M.R., Stark, W.M. , Piccirilli, J.A. and Rice, P.A. (2010) Sin resolvase catalytic activity and oligomerization state are tightly coupled. Journal of Molecular Biology, 404(1), pp. 16-33. (doi: 10.1016/j.jmb.2010.08.057)
Rice, P.A., Mouw, K.W., Montaño, S.P., Boocock, M.R., Rowland, S.-J. and Stark, W.M. (2010) Orchestrating serine resolvases. Biochemical Society Transactions, 38(2), pp. 384-387. (doi: 10.1042/BST0380384)
2009
Rowland, S.J., Boocock, M.R., MacPherson, A.L., Mouw, K.W., Rice, P.A. and Stark, M.S. (2009) Regulatory mutations in Sin recombinase support a structure-based model of the synaptosome. Molecular Microbiology, 74(2), pp. 282-298. (doi: 10.1111/j.1365-2958.2009.06756.x)
2008
Olorunniji, F.J., He, J., Wenwieser, S.V.C.T., Boocock, M.R. and Stark, W.M. (2008) Synapsis and catalysis by activated Tn3 resolvase mutants. Nucleic Acids Research, 36(22), pp. 7181-7191. (doi: 10.1093/nar/gkn885)
Mouw, K.W., Rowland, S.-J., Gajjar, M.M., Boocock, M.R., Stark, W.M. and Rice, P.A. (2008) Architecture of a serine recombinase-DNA regulatory complex. Molecular Cell, 30(2), pp. 145-155. (doi: 10.1016/j.molcel.2008.02.023)
Articles
Cadden, G. M., Schloetel, J.-G., McKenzie, G. , Boocock, M. R., Magennis, S. W. and Stark, W. M. (2024) Direct observation of subunit rotation during DNA strand exchange by serine recombinases. Nature Communications, 15, 10407. (doi: 10.1038/s41467-024-54531-4) (PMID:39613732) (PMCID:PMC11607074)
Montaño, S. P., Rowland, S.-J., Fuller, J. R., Burke, M. E., MacDonald, A. I., Boocock, M. R., Stark, W. M. and Rice, P. A. (2023) Structural basis for topological regulation of Tn3 resolvase. Nucleic Acids Research, 51(3), pp. 1001-1018. (doi: 10.1093/nar/gkac733) (PMID:36100255) (PMCID:PMC9943657)
Rowland, S.-J., Boocock, M. R., Burke, M. E., Rice, P. A. and Stark, W. M. (2020) The protein-protein interactions required for assembly of the Tn3 resolution synapse. Molecular Microbiology, 114(6), pp. 952-965. (doi: 10.1111/mmi.14579) (PMID:33405333)
Trejo, C. S., Rock, R. S., Stark, W. M. , Boocock, M. R. and Rice, P. A. (2018) Snapshots of a molecular swivel in action. Nucleic Acids Research, 46(10), pp. 5286-5296. (doi: 10.1093/nar/gkx1309) (PMID:29315406) (PMCID:PMC6007550)
Keenholtz, R.A., Mouw, K.W., Boocock, M.R., Li, N.-S., Piccirilli, J.A. and Rice, P.A. (2013) Arginine as a general acid catalyst in serine recombinase-mediated DNA cleavage. Journal of Biological Chemistry, 288(40), pp. 29206-29214. (doi: 10.1074/jbc.M113.508028)
Misiura, A., Pigli, Y.Z., Boyle-Vavra, S., Daum, R.S., Boocock, M.R. and Rice, P.A. (2013) Roles of two large serine recombinases in mobilizing the methicillin-resistance cassette SCCmec. Molecular Microbiology, 88(6), pp. 1218-1229. (doi: 10.1111/mmi.12253)
Boocock, M.R. and Rice, P.A. (2013) A proposed mechanism for IS607-family serine transposases. Mobile DNA, 4(24), (doi: 10.1186/1759-8753-4-24)
Keenholtz, R.A., Rowland, S.-J., Boocock, M.R., Stark, W.M. and Rice, P.A. (2011) Structural Basis for Catalytic Activation of a Serine Recombinase. Structure, 19(6), pp. 799-809. (doi: 10.1016/j.str.2011.03.017)
Stark, W.M. , Boocock, M.R., Olorunniji, F.J. and Rowland, S.-J. (2011) Intermediates in serine recombinase-mediated site-specific recombination. Biochemical Society Transactions, 39(2), pp. 617-622. (doi: 10.1042/BST0390617)
Mouw, K.W., Steiner, A.M., Ghirlando, R., Li, N.-S., Rowland, S.-J., Boocock, M.R., Stark, W.M. , Piccirilli, J.A. and Rice, P.A. (2010) Sin resolvase catalytic activity and oligomerization state are tightly coupled. Journal of Molecular Biology, 404(1), pp. 16-33. (doi: 10.1016/j.jmb.2010.08.057)
Rice, P.A., Mouw, K.W., Montaño, S.P., Boocock, M.R., Rowland, S.-J. and Stark, W.M. (2010) Orchestrating serine resolvases. Biochemical Society Transactions, 38(2), pp. 384-387. (doi: 10.1042/BST0380384)
Rowland, S.J., Boocock, M.R., MacPherson, A.L., Mouw, K.W., Rice, P.A. and Stark, M.S. (2009) Regulatory mutations in Sin recombinase support a structure-based model of the synaptosome. Molecular Microbiology, 74(2), pp. 282-298. (doi: 10.1111/j.1365-2958.2009.06756.x)
Olorunniji, F.J., He, J., Wenwieser, S.V.C.T., Boocock, M.R. and Stark, W.M. (2008) Synapsis and catalysis by activated Tn3 resolvase mutants. Nucleic Acids Research, 36(22), pp. 7181-7191. (doi: 10.1093/nar/gkn885)
Mouw, K.W., Rowland, S.-J., Gajjar, M.M., Boocock, M.R., Stark, W.M. and Rice, P.A. (2008) Architecture of a serine recombinase-DNA regulatory complex. Molecular Cell, 30(2), pp. 145-155. (doi: 10.1016/j.molcel.2008.02.023)
Research datasets
2024
Cadden, G., Schloetel, J.-G., McKenzie, G., Boocock, M., Magennis, S. and Stark, M. (2024) Direct observation of subunit rotation during DNA strand exchange by serine recombinases. [Data Collection]