Dr Marcel Van Lith
- Research Associate (Molecular Biosciences)
telephone:
01413306453
email:
Marcel.VanLith@glasgow.ac.uk
Lab 232, Institute of MC&SB, Davidson Building, Glasgow G12 8QQ
Publications
2021
van Lith, M., Pringle, M. A. , Fleming, B., Gaeta, G., Im, J., Gilmore, R. and Bulleid, N. J. (2021) A cytosolic reductase pathway is required for efficient N-glycosylation of an STT3B-dependent acceptor site. Journal of Cell Science, 134(22), jcs259340. (doi: 10.1242/jcs.259340) (PMID:34734627) (PMCID:PMC8645230)
2020
Cao, X., Lilla, S., Cao, Z., Pringle, M. A., Oka, O. B.V. , Robinson, P. J. , Szmaja, T., Van Lith, M., Zanivan, S. and Bulleid, N. (2020) The mammalian cytosolic thioredoxin reductase pathway acts via a membrane 1 protein to reduce ER-localised proteins. Journal of Cell Science, 133, jcs241976. (doi: 10.1242/jcs.241976) (PMID:32184267) (PMCID:PMC7197872)
2019
Oka, O. B.V. , van Lith, M., Rudolf, J., Tungkum, W., Pringle, M.-A. and Bulleid, N. J. (2019) ERp18 regulates the activation of ATF6α during the unfolded protein response. EMBO Journal, 2019, e100990. (doi: 10.15252/embj.2018100990) (PMID:31209066)
2017
Chalmers, F., van Lith, M., Sweeney, B., Cain, K. and Bulleid, N. J. (2017) Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response. Wellcome Open Research, 2, 36. (doi: 10.12688/wellcomeopenres.11764.2) (PMID:29062910) (PMCID:PMC5645705)
Poet, G. J., Oka, O. B.V. , Van Lith, M., Cao, Z., Robinson, P. J. , Pringle, M. A. , Arnér, E. S.J. and Bulleid, N. (2017) Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER. EMBO Journal, 36(5), pp. 693-702. (doi: 10.15252/embj.201695336) (PMID:28093500) (PMCID:PMC5331760)
2016
Cao, Z., Van Lith, M., Mitchell, L. J., Pringle, M. A. , Inaba, K. and Bulleid, N. J. (2016) The membrane topology of vitamin K epoxide reductase is conserved between human isoforms and the bacterial enzyme. Biochemical Journal, 473(7), pp. 851-858. (doi: 10.1042/bj20151223) (PMID:26772871)
2014
Bulleid, N. J. and van Lith, M. (2014) Redox regulation in the endoplasmic reticulum. Biochemical Society Transactions, 42(4), pp. 905-908. (doi: 10.1042/BST20140065)
2013
Benham, A.M., Van Lith, M., Sitia, R. and Braakman, I. (2013) Ero1-PDI interactions, the response to redox flux and the implications for disulfide bond formation in the mammalian endoplasmic reticulum. Philosophical Transactions of the Royal Society B: Biological Sciences, 368(1617), Art. 20110403. (doi: 10.1098/rstb.2011.0403)
2011
Van Lith, M., Tiwari, S., Pediani, J. , Milligan, G. and Bulleid, N. J. (2011) Real-time monitoring of redox changes in the mammalian endoplasmic reticulum. Journal of Cell Science, 124(14), pp. 2349-2356. (doi: 10.1242/jcs.085530)
Articles
van Lith, M., Pringle, M. A. , Fleming, B., Gaeta, G., Im, J., Gilmore, R. and Bulleid, N. J. (2021) A cytosolic reductase pathway is required for efficient N-glycosylation of an STT3B-dependent acceptor site. Journal of Cell Science, 134(22), jcs259340. (doi: 10.1242/jcs.259340) (PMID:34734627) (PMCID:PMC8645230)
Cao, X., Lilla, S., Cao, Z., Pringle, M. A., Oka, O. B.V. , Robinson, P. J. , Szmaja, T., Van Lith, M., Zanivan, S. and Bulleid, N. (2020) The mammalian cytosolic thioredoxin reductase pathway acts via a membrane 1 protein to reduce ER-localised proteins. Journal of Cell Science, 133, jcs241976. (doi: 10.1242/jcs.241976) (PMID:32184267) (PMCID:PMC7197872)
Oka, O. B.V. , van Lith, M., Rudolf, J., Tungkum, W., Pringle, M.-A. and Bulleid, N. J. (2019) ERp18 regulates the activation of ATF6α during the unfolded protein response. EMBO Journal, 2019, e100990. (doi: 10.15252/embj.2018100990) (PMID:31209066)
Chalmers, F., van Lith, M., Sweeney, B., Cain, K. and Bulleid, N. J. (2017) Inhibition of IRE1α-mediated XBP1 mRNA cleavage by XBP1 reveals a novel regulatory process during the unfolded protein response. Wellcome Open Research, 2, 36. (doi: 10.12688/wellcomeopenres.11764.2) (PMID:29062910) (PMCID:PMC5645705)
Poet, G. J., Oka, O. B.V. , Van Lith, M., Cao, Z., Robinson, P. J. , Pringle, M. A. , Arnér, E. S.J. and Bulleid, N. (2017) Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER. EMBO Journal, 36(5), pp. 693-702. (doi: 10.15252/embj.201695336) (PMID:28093500) (PMCID:PMC5331760)
Cao, Z., Van Lith, M., Mitchell, L. J., Pringle, M. A. , Inaba, K. and Bulleid, N. J. (2016) The membrane topology of vitamin K epoxide reductase is conserved between human isoforms and the bacterial enzyme. Biochemical Journal, 473(7), pp. 851-858. (doi: 10.1042/bj20151223) (PMID:26772871)
Bulleid, N. J. and van Lith, M. (2014) Redox regulation in the endoplasmic reticulum. Biochemical Society Transactions, 42(4), pp. 905-908. (doi: 10.1042/BST20140065)
Benham, A.M., Van Lith, M., Sitia, R. and Braakman, I. (2013) Ero1-PDI interactions, the response to redox flux and the implications for disulfide bond formation in the mammalian endoplasmic reticulum. Philosophical Transactions of the Royal Society B: Biological Sciences, 368(1617), Art. 20110403. (doi: 10.1098/rstb.2011.0403)
Van Lith, M., Tiwari, S., Pediani, J. , Milligan, G. and Bulleid, N. J. (2011) Real-time monitoring of redox changes in the mammalian endoplasmic reticulum. Journal of Cell Science, 124(14), pp. 2349-2356. (doi: 10.1242/jcs.085530)