2024

Hermantara, R., Richmond, L., Taqi, A. F., Chilaka, S., Jeantet, V., Guerrini, I., West, K. and West, A. (2024) Improving CRISPR-Cas9 directed faithful transgene integration outcomes by reducing unwanted random DNA integration. Journal of Biomedical Science, 31(1), 32. (doi: 10.1186/s12929-024-01020-x) (PMID:38532479) (PMCID:PMC10964699)

2019

Garza-Manero, S. et al. (2019) Maintenance of active chromatin states by HMGN2 is required for stem cell identity in a pluripotent stem cell model. Epigenetics and Chromatin, 12, 73. (doi: 10.1186/s13072-019-0320-7) (PMID:31831052) (PMCID:PMC6907237)

2018

Bilsland, A. , Kelly, C. , Roccisana, J., Paul, J. , Jones, R. , Edwards, J. , Roseweir, A. , Stein, T. and West, K. (2018) An Exploratory Study on the Use of Game-based Learning Using Microsoft Kinect to Teach Oncology Phase I Clinical Trial Designs. 2018 NCRI Cancer Conference, Glasgow, UK, 04-06 Nov 2018. (doi: 10.1038/s41416-018-0299-z)

2016

Garza-Manero, S., Sindi, A., Bailo, M., Mohan, G., Rehbini, O., Jeantet, V., West, A. and West, K. (2016) Nucleosome-binding HMGN Proteins Inhibit Stem Cell Differentiation Down the Neuronal Lineage. 2016 IMB Conference: Epigenetics in Development, Mainz, Germany, 20-22 Oct 2016.

West, K. L. , Roccisana, J., Stein, T. and Williams, M. (2016) Can a Multi-Student Research Project Deliver a High Quality Learning Experience at Masters Level? MVLS PGT Annual Away Day, Glasgow, UK, 07 Sep 2016.

Rehbini, O., Mohan, G., Sindi, A., Garza Manero, S., Gurden, R., Iwata, T. and West, K. (2016) Knockdown High Mobility Nucleosomal Binding Proteins 2 (HMGN2) Alter the Histone Modification H4K4me3 and H3K27me3 and Regulates Stem Cells Pluripotency. 9th Saudi Student Conference, Birmingham, UK, 13-14 Feb 2016.

2015

Carvalho Mendez, E., Sindi, A., Rehbini, O. and West, K. L. (2015) HMGN3a Localization and HMGNs Expressoin in P19 Embryonal Carcinoma Cells. 61st Congresso Brasileiro de Genética, São Paulo, Brazil, 08-11 Sep 2015.

Rehbini, O., Sindi, A., Mohan, G., Garza Manero, S., Iwata, T. and West, K. L. (2015) The Hmgn Family of Chromatin Binding Proteins Regulates Stem Cells Pluripotency and Neuronal Differentiation. Wellcome Trust-Waddington Symposium: Epigenetics in Dialogue with THE GENOME, Edinburgh, UK, 01-05 Jun 2015.

Sindi, A., Garza Manero, S., Mohan, G., Rehbini, O., Carvalho Mendez, E. and West, K. L. (2015) Characterising the HMGN Proteins Expression, and their Role, During Neuronal Differentiation of Mouse P19-ECCs in a Defined Adherent Culture System. BNA2015: Festival of Neuroscience, Edinburgh, UK, 12-15 Apr 2015.

2014

West, K. , Gourlay, E. and West, A. (2014) Genome Editing in Human Cells. Tenovus Scotland Scholarship Event, Glasgow, UK, 25 Jul 2014.

2012

Mohan, G., Rehbini, O., Iwata, T. and West, K. (2012) The Hmgn Family of Chromatin Binding Proteins Regulate Stem Cell Pluripotency and Neuronal Differentiation. Biochemical Society Annual Symposium: Epigenetic Mechanisms in Development and Disease, Leeds, UK, 11-13 Dec 2012.

Barkess, G., Postnikov, Y., Campos, C.D., Mishra, S., Mohan, G., Verma, S., Bustin, M. and West, K.L. (2012) The chromatin-binding protein HMGN3 stimulates histone acetylation and transcription across the Glyt1 gene. Biochemical Journal, 442(3), pp. 495-505. (doi: 10.1042/BJ20111502) (PMID:22150271) (PMCID:PMC3713072)

Jiwaji, M. et al. (2012) Unique reporter-based sensor platforms to monitor signalling in cells. PLoS ONE, 7(11), e50521. (doi: 10.1371/journal.pone.0050521) (PMID:23209767) (PMCID:PMC3510088)

2008

Meczes, E.L., Gilroy, K.L., West, K.L. and Austin, C.A. (2008) The impact of the human DNA topoisomerase II C-terminal domain on activity. PLoS ONE, 3(3), e1754. (doi: 10.1371/journal.pone.0001754) (PMID:18335031) (PMCID:PMC2262138)

2005

Rubinstein, Y. R., Furusawa, T., Lim, J.-H., Postnikov, Y. V., West, K. L. , Birger, Y., Lee, S., Nguyen, P., Trepel, J. B. and Bustin, M. (2005) Chromosomal protein HMGN1 modulates the expression of N-cadherin. FEBS Journal, 272(22), pp. 5853-5863. (doi: 10.1111/j.1742-4658.2005.04980.x)

Birger, Y., Catez, F., Furusawa, T., Lim, J., Prymakowska-Bosak, M., West, K., Postnikov, Y., Haines, D. and Bustin, M. (2005) Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1. Cancer Research, 65(15), pp. 6711-6718.

Lim, J., West, K., Rubinstein, Y., Bergel, M., Postnikov, Y. and Bustin, M. (2005) Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3. EMBO Journal, 24(17), pp. 3038-3048.

2004

Lim, J., Catez, F., Birger, Y., West, K., Prymakowska-Bosak, M., Postnikov, Y. and Bustin, M. (2004) Chromosomal protein HMGN1 modulates histone H3 phosphorylation. Molecular Cell, 15(4), pp. 573-584.

West, K.L. and Bustin, M. (2004) The role of HMGN proteins in chromatin function. In: Zlatanova, J. and Leuba, S.H. (eds.) Chromatin Structure and Dynamics: State-of-the-Art. Series: New comprehensive biochemistry (39). Elsevier: Amsterdam, The Netherlands, pp. 135-154. ISBN 9780444515940

West, K. (2004) HMGN proteins play roles in DNA repair and gene expression in mammalian cells. Biochemical Society Transactions, 32, pp. 918-919.

West, K., Castellini, M., Duncan, M. and Bustin, M. (2004) Chromosomal proteins HMGN3a and HMGN3b regulate the expression of glycine transporter 1. Molecular and Cellular Biology, 24, pp. 3747-3756. (doi: 10.1128/MCB.24.9.3747-3756.2004)

2003

Birger, Y., West, K., Postnikov, Y., Lim, J., Furusawa, T., Wagner, J., Laufer, C., Kraemer, K. and Bustin, M. (2003) Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin. EMBO Journal, 22(7), pp. 1665-1675.

West, K., Postnikov, Y., Birger, Y. and Bustin, M. (2003) Chromatin decompaction method by HMGN proteins. Methods in Enzymology, 371, pp. 521-536.

2002

West, K., Turnbull, R., Willmore, E., Lakey, J. and Austin, C. (2002) Characterisation of the DNA-dependent ATPase activity of human DNA topoisomerase IIbeta: mutation of Ser165 in the ATPase domain reduces the ATPase activity and abolishes the in vivo complementation ability. Nucleic Acids Research, 30(24), pp. 5416-5424.

2001

Birger, Y., Ito, Y., West, K.L., Landsman, D. and Bustin, M. (2001) HMGN4, a new nucleosomal binding protein encoded by an intronless gene. DNA and Cell Biology, 20(5), pp. 257-264.

West, K., Ito, Y., Birger, Y., Postnikov, Y., Shirakawa, H. and Bustin, M. (2001) HMGN3a and HMGN3b, two protein isoforms with a tissue-specific expression pattern, expand the cellular repertoire of nucleosome- binding proteins. Journal of Biological Chemistry, 276(28), pp. 25959-25969.

1996

Zandvliet, D. W.J., Hanby, A. M., Austin, C. A., Marsh, K. L. , Clark, I. B.N., Wright, N. A. and Poulsom, R. (1996) Analysis of foetal expression sites of human type II DNA topoisomerase α and β mRNAs by in situ hybridisation. Biochimica et Biophysica Acta: Gene Structure and Expression, 1307(2), pp. 239-247. (doi: 10.1016/0167-4781(96)00063-2) (PMID:8679710)

Articles

Hermantara, R., Richmond, L., Taqi, A. F., Chilaka, S., Jeantet, V., Guerrini, I., West, K. and West, A. (2024) Improving CRISPR-Cas9 directed faithful transgene integration outcomes by reducing unwanted random DNA integration. Journal of Biomedical Science, 31(1), 32. (doi: 10.1186/s12929-024-01020-x) (PMID:38532479) (PMCID:PMC10964699)

Garza-Manero, S. et al. (2019) Maintenance of active chromatin states by HMGN2 is required for stem cell identity in a pluripotent stem cell model. Epigenetics and Chromatin, 12, 73. (doi: 10.1186/s13072-019-0320-7) (PMID:31831052) (PMCID:PMC6907237)

Barkess, G., Postnikov, Y., Campos, C.D., Mishra, S., Mohan, G., Verma, S., Bustin, M. and West, K.L. (2012) The chromatin-binding protein HMGN3 stimulates histone acetylation and transcription across the Glyt1 gene. Biochemical Journal, 442(3), pp. 495-505. (doi: 10.1042/BJ20111502) (PMID:22150271) (PMCID:PMC3713072)

Jiwaji, M. et al. (2012) Unique reporter-based sensor platforms to monitor signalling in cells. PLoS ONE, 7(11), e50521. (doi: 10.1371/journal.pone.0050521) (PMID:23209767) (PMCID:PMC3510088)

Meczes, E.L., Gilroy, K.L., West, K.L. and Austin, C.A. (2008) The impact of the human DNA topoisomerase II C-terminal domain on activity. PLoS ONE, 3(3), e1754. (doi: 10.1371/journal.pone.0001754) (PMID:18335031) (PMCID:PMC2262138)

Rubinstein, Y. R., Furusawa, T., Lim, J.-H., Postnikov, Y. V., West, K. L. , Birger, Y., Lee, S., Nguyen, P., Trepel, J. B. and Bustin, M. (2005) Chromosomal protein HMGN1 modulates the expression of N-cadherin. FEBS Journal, 272(22), pp. 5853-5863. (doi: 10.1111/j.1742-4658.2005.04980.x)

Birger, Y., Catez, F., Furusawa, T., Lim, J., Prymakowska-Bosak, M., West, K., Postnikov, Y., Haines, D. and Bustin, M. (2005) Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1. Cancer Research, 65(15), pp. 6711-6718.

Lim, J., West, K., Rubinstein, Y., Bergel, M., Postnikov, Y. and Bustin, M. (2005) Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3. EMBO Journal, 24(17), pp. 3038-3048.

Lim, J., Catez, F., Birger, Y., West, K., Prymakowska-Bosak, M., Postnikov, Y. and Bustin, M. (2004) Chromosomal protein HMGN1 modulates histone H3 phosphorylation. Molecular Cell, 15(4), pp. 573-584.

West, K. (2004) HMGN proteins play roles in DNA repair and gene expression in mammalian cells. Biochemical Society Transactions, 32, pp. 918-919.

West, K., Castellini, M., Duncan, M. and Bustin, M. (2004) Chromosomal proteins HMGN3a and HMGN3b regulate the expression of glycine transporter 1. Molecular and Cellular Biology, 24, pp. 3747-3756. (doi: 10.1128/MCB.24.9.3747-3756.2004)

Birger, Y., West, K., Postnikov, Y., Lim, J., Furusawa, T., Wagner, J., Laufer, C., Kraemer, K. and Bustin, M. (2003) Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin. EMBO Journal, 22(7), pp. 1665-1675.

West, K., Postnikov, Y., Birger, Y. and Bustin, M. (2003) Chromatin decompaction method by HMGN proteins. Methods in Enzymology, 371, pp. 521-536.

West, K., Turnbull, R., Willmore, E., Lakey, J. and Austin, C. (2002) Characterisation of the DNA-dependent ATPase activity of human DNA topoisomerase IIbeta: mutation of Ser165 in the ATPase domain reduces the ATPase activity and abolishes the in vivo complementation ability. Nucleic Acids Research, 30(24), pp. 5416-5424.

Birger, Y., Ito, Y., West, K.L., Landsman, D. and Bustin, M. (2001) HMGN4, a new nucleosomal binding protein encoded by an intronless gene. DNA and Cell Biology, 20(5), pp. 257-264.

West, K., Ito, Y., Birger, Y., Postnikov, Y., Shirakawa, H. and Bustin, M. (2001) HMGN3a and HMGN3b, two protein isoforms with a tissue-specific expression pattern, expand the cellular repertoire of nucleosome- binding proteins. Journal of Biological Chemistry, 276(28), pp. 25959-25969.

Zandvliet, D. W.J., Hanby, A. M., Austin, C. A., Marsh, K. L. , Clark, I. B.N., Wright, N. A. and Poulsom, R. (1996) Analysis of foetal expression sites of human type II DNA topoisomerase α and β mRNAs by in situ hybridisation. Biochimica et Biophysica Acta: Gene Structure and Expression, 1307(2), pp. 239-247. (doi: 10.1016/0167-4781(96)00063-2) (PMID:8679710)

Book Sections

West, K.L. and Bustin, M. (2004) The role of HMGN proteins in chromatin function. In: Zlatanova, J. and Leuba, S.H. (eds.) Chromatin Structure and Dynamics: State-of-the-Art. Series: New comprehensive biochemistry (39). Elsevier: Amsterdam, The Netherlands, pp. 135-154. ISBN 9780444515940

Conference or Workshop Item

Bilsland, A. , Kelly, C. , Roccisana, J., Paul, J. , Jones, R. , Edwards, J. , Roseweir, A. , Stein, T. and West, K. (2018) An Exploratory Study on the Use of Game-based Learning Using Microsoft Kinect to Teach Oncology Phase I Clinical Trial Designs. 2018 NCRI Cancer Conference, Glasgow, UK, 04-06 Nov 2018. (doi: 10.1038/s41416-018-0299-z)

Garza-Manero, S., Sindi, A., Bailo, M., Mohan, G., Rehbini, O., Jeantet, V., West, A. and West, K. (2016) Nucleosome-binding HMGN Proteins Inhibit Stem Cell Differentiation Down the Neuronal Lineage. 2016 IMB Conference: Epigenetics in Development, Mainz, Germany, 20-22 Oct 2016.

West, K. L. , Roccisana, J., Stein, T. and Williams, M. (2016) Can a Multi-Student Research Project Deliver a High Quality Learning Experience at Masters Level? MVLS PGT Annual Away Day, Glasgow, UK, 07 Sep 2016.

Rehbini, O., Mohan, G., Sindi, A., Garza Manero, S., Gurden, R., Iwata, T. and West, K. (2016) Knockdown High Mobility Nucleosomal Binding Proteins 2 (HMGN2) Alter the Histone Modification H4K4me3 and H3K27me3 and Regulates Stem Cells Pluripotency. 9th Saudi Student Conference, Birmingham, UK, 13-14 Feb 2016.

Carvalho Mendez, E., Sindi, A., Rehbini, O. and West, K. L. (2015) HMGN3a Localization and HMGNs Expressoin in P19 Embryonal Carcinoma Cells. 61st Congresso Brasileiro de Genética, São Paulo, Brazil, 08-11 Sep 2015.

Rehbini, O., Sindi, A., Mohan, G., Garza Manero, S., Iwata, T. and West, K. L. (2015) The Hmgn Family of Chromatin Binding Proteins Regulates Stem Cells Pluripotency and Neuronal Differentiation. Wellcome Trust-Waddington Symposium: Epigenetics in Dialogue with THE GENOME, Edinburgh, UK, 01-05 Jun 2015.

Sindi, A., Garza Manero, S., Mohan, G., Rehbini, O., Carvalho Mendez, E. and West, K. L. (2015) Characterising the HMGN Proteins Expression, and their Role, During Neuronal Differentiation of Mouse P19-ECCs in a Defined Adherent Culture System. BNA2015: Festival of Neuroscience, Edinburgh, UK, 12-15 Apr 2015.

West, K. , Gourlay, E. and West, A. (2014) Genome Editing in Human Cells. Tenovus Scotland Scholarship Event, Glasgow, UK, 25 Jul 2014.

Mohan, G., Rehbini, O., Iwata, T. and West, K. (2012) The Hmgn Family of Chromatin Binding Proteins Regulate Stem Cell Pluripotency and Neuronal Differentiation. Biochemical Society Annual Symposium: Epigenetic Mechanisms in Development and Disease, Leeds, UK, 11-13 Dec 2012.