Professor Dominic Meek
- Honorary Professor (School of Molecular Biosciences)
Publications
2024
Young, P., Greer, A. I.M. , Smith, C.-A. , Silverwood, R., Tsimbouri, P. M. , Meek, D., Goodyear, C., Gadegaard, N. and Dalby, M. J. (2024) Titanium surface synergy: strontium incorporation and controlled disorder nanotopography optimise osteoinduction. ACS Applied Materials and Interfaces, (doi: 10.1021/acsami.4c04117) (Early Online Publication)
Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0)
Jenkinson, M. R.J., Meek, D. R.M., Tate, R., Brady, A., MacMillan, S., Grant, H. and Currie, S. (2024) Cardiac function may be compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. Bone and Joint Journal, 106-B(3A), pp. 51-58. (doi: 10.1302/0301-620X.106B3.BJJ-2023-0814.R1) (PMID:38423080)
2023
Magan, A. A., Radhakrishnan, G. T., Kayani, B., Ronca, F., Khanduja, V., Meek, R. M.D. and Haddad, F. S. (2023) Time for return to sport following total hip arthroplasty: a meta-analysis. HIP International, 33(2), pp. 221-230. (doi: 10.1177/11207000211041975) (PMID:34538122)
2022
Xiao, Y., Donnelly, H. , Sprott, M. , Luo, J., Jayawarna, V., Lemgruber, L. , Tsimbouri, P. M. , Meek, R.M. D., Salmeron-Sanchez, M. and Dalby, M. J. (2022) Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis. Materials Today Bio, 16, 100367. (doi: 10.1016/j.mtbio.2022.100367) (PMID:35937570) (PMCID:PMC9352550)
Mcvey, L., Kane, N., Murray, H., Meek, R.M. D. and Ahmed, S. F. (2022) Elective hip arthroplasty rates and related complications in people with diabetes mellitus. HIP International, 32(6), pp. 717-723. (doi: 10.1177/1120700020981573) (PMID:33334203)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
2020
Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)
2018
Marsh, A. G., Nisar, A., El Refai, M., Patil, S. and Meek, R. M. D. (2018) Can we predict which dysplastic hips will require acetabular augmentation during total hip arthroplasty based on pre-operative radiographs? Bone and Joint Journal, 99-B(4), pp. 445-450. (doi: 10.1302/0301-620x.99b4.bjj-2016-0041.r1) (PMID:28385932)
Allan, C., Ker, A., Smith, C.-A. , Tsimbouri, P. , Borsoi, J., O'Neill, S., Gadegaard, N. , Dalby, M. J. and Meek, D. (2018) Osteoblast response to disordered nanotopography. Journal of Tissue Engineering, 9, pp. 1-7. (doi: 10.1177/2041731418784098) (PMID:30034770) (PMCID:PMC6048666)
2017
Ballester-Beltrán, J., Trujillo Munoz, S. , Alakpa, E. V., Compañ, V., Gavara, R., Meek, D., West, C. C., Péault, B., Dalby, M. J. and Salmeron-Sanchez, M. (2017) Confined sandwichlike microenvironments tune myogenic differentiation. ACS Biomaterials Science and Engineering, 3(8), pp. 1710-1718. (doi: 10.1021/acsbiomaterials.7b00109) (PMID:28824958) (PMCID:PMC5558191)
Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)
Donnelly, H. , Smith, C.-A. , Sweeten, P. E., Gadegaard, N. , Meek, D., D'Este, M., Mata, A., Eglin, D. and Dalby, M. J. (2017) Bone and cartilage differentiation of a single stem cell population driven by material interface. Journal of Tissue Engineering, 8, pp. 1-10. (doi: 10.1177/2041731417705615) (PMID:28567273) (PMCID:PMC5438107)
2016
Davison, M. J., McMurray, R. J., Smith, C.-A. , Dalby, M. and Meek, R.M. D. (2016) Nanopit-induced osteoprogenitor cell differentiation: the effect of nanopit death. Journal of Tissue Engineering, 7, pp. 1-8. (doi: 10.1177/2041731416652778) (PMID:27298716)
2015
Stipetic, L. H., Hamilton, G., Dalby, M. J. , Davies, R. L. , Meek, R.M. D., Ramage, G. , Smith, D. G.E. and Burgess, K. E.V. (2015) Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip. Genome Announcements, 3(2), e00336-15. (doi: 10.1128/genomeA.00336-15) (PMID:25931597) (PMCID:PMC4417693)
2014
Halai, M., Ker, A., Meek, R.M. D., Nadeem, D., Sjostrom, T., Su, B., McNamara, L. E., Dalby, M. J. and Young, P. S. (2014) Scanning electron microscopical observation of an osteoblast/osteoclast co-culture on micropatterned orthopaedic ceramics. Journal of Tissue Engineering, 5, (doi: 10.1177/2041731414552114) (PMID:25383174) (PMCID:PMC4221946)
McNamara, L. E., Sjostrom, T., Seunarine, K., Meek, R.M. D., Su, B. and Dalby, M. J. (2014) Investigation of the limits of nanoscale filopodial interactions. Journal of Tissue Engineering, 5, p. 2041731414536177. (doi: 10.1177/2041731414536177) (PMID:24904726) (PMCID:PMC4046805)
Yang, J., McNamara, L. E., Gadegaard, N. , Alakpa, E. V., Burgess, K. V., Meek, D. and Dalby, M. J. (2014) Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs. ACS Nano, 8(10), pp. 9941-9953. (doi: 10.1021/nn504767g) (PMID:25227207)
2012
Maclaine, S.E., Gadhari, N., Pugin, R., Meek, R.M.D., Liley, M. and Dalby, M.J. (2012) Optimizing the osteogenicity of nanotopography using block co-polymer phase separation fabrication techniques. Journal of Orthopaedic Research, 30(8), pp. 1190-1197. (doi: 10.1002/jor.22076)
2011
McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)
Wilkinson, A., Hewitt, R. N., McNamara, L. E., McCloy, D., Meek, R.M. D. and Dalby, M. J. (2011) Biomimetic microtopography to enhance osteogenesis in vitro. Acta Biomaterialia, 7(7), pp. 2919-2925. (doi: 10.1016/j.actbio.2011.03.026)
2009
Ogunwale, B., Schmidt-Ott, A., Meek, R. M. D. and Brewer, J. M. (2009) Investigating the immunologic effects of CoCr nanoparticles. Clinical Orthopaedics and Related Research, 467(11), 3010. (doi: 10.1007/s11999-009-0949-9) (PMID:19565304) (PMCID:PMC2758989)
Articles
Young, P., Greer, A. I.M. , Smith, C.-A. , Silverwood, R., Tsimbouri, P. M. , Meek, D., Goodyear, C., Gadegaard, N. and Dalby, M. J. (2024) Titanium surface synergy: strontium incorporation and controlled disorder nanotopography optimise osteoinduction. ACS Applied Materials and Interfaces, (doi: 10.1021/acsami.4c04117) (Early Online Publication)
Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0)
Jenkinson, M. R.J., Meek, D. R.M., Tate, R., Brady, A., MacMillan, S., Grant, H. and Currie, S. (2024) Cardiac function may be compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. Bone and Joint Journal, 106-B(3A), pp. 51-58. (doi: 10.1302/0301-620X.106B3.BJJ-2023-0814.R1) (PMID:38423080)
Magan, A. A., Radhakrishnan, G. T., Kayani, B., Ronca, F., Khanduja, V., Meek, R. M.D. and Haddad, F. S. (2023) Time for return to sport following total hip arthroplasty: a meta-analysis. HIP International, 33(2), pp. 221-230. (doi: 10.1177/11207000211041975) (PMID:34538122)
Xiao, Y., Donnelly, H. , Sprott, M. , Luo, J., Jayawarna, V., Lemgruber, L. , Tsimbouri, P. M. , Meek, R.M. D., Salmeron-Sanchez, M. and Dalby, M. J. (2022) Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis. Materials Today Bio, 16, 100367. (doi: 10.1016/j.mtbio.2022.100367) (PMID:35937570) (PMCID:PMC9352550)
Mcvey, L., Kane, N., Murray, H., Meek, R.M. D. and Ahmed, S. F. (2022) Elective hip arthroplasty rates and related complications in people with diabetes mellitus. HIP International, 32(6), pp. 717-723. (doi: 10.1177/1120700020981573) (PMID:33334203)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)
Marsh, A. G., Nisar, A., El Refai, M., Patil, S. and Meek, R. M. D. (2018) Can we predict which dysplastic hips will require acetabular augmentation during total hip arthroplasty based on pre-operative radiographs? Bone and Joint Journal, 99-B(4), pp. 445-450. (doi: 10.1302/0301-620x.99b4.bjj-2016-0041.r1) (PMID:28385932)
Allan, C., Ker, A., Smith, C.-A. , Tsimbouri, P. , Borsoi, J., O'Neill, S., Gadegaard, N. , Dalby, M. J. and Meek, D. (2018) Osteoblast response to disordered nanotopography. Journal of Tissue Engineering, 9, pp. 1-7. (doi: 10.1177/2041731418784098) (PMID:30034770) (PMCID:PMC6048666)
Ballester-Beltrán, J., Trujillo Munoz, S. , Alakpa, E. V., Compañ, V., Gavara, R., Meek, D., West, C. C., Péault, B., Dalby, M. J. and Salmeron-Sanchez, M. (2017) Confined sandwichlike microenvironments tune myogenic differentiation. ACS Biomaterials Science and Engineering, 3(8), pp. 1710-1718. (doi: 10.1021/acsbiomaterials.7b00109) (PMID:28824958) (PMCID:PMC5558191)
Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)
Donnelly, H. , Smith, C.-A. , Sweeten, P. E., Gadegaard, N. , Meek, D., D'Este, M., Mata, A., Eglin, D. and Dalby, M. J. (2017) Bone and cartilage differentiation of a single stem cell population driven by material interface. Journal of Tissue Engineering, 8, pp. 1-10. (doi: 10.1177/2041731417705615) (PMID:28567273) (PMCID:PMC5438107)
Davison, M. J., McMurray, R. J., Smith, C.-A. , Dalby, M. and Meek, R.M. D. (2016) Nanopit-induced osteoprogenitor cell differentiation: the effect of nanopit death. Journal of Tissue Engineering, 7, pp. 1-8. (doi: 10.1177/2041731416652778) (PMID:27298716)
Stipetic, L. H., Hamilton, G., Dalby, M. J. , Davies, R. L. , Meek, R.M. D., Ramage, G. , Smith, D. G.E. and Burgess, K. E.V. (2015) Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip. Genome Announcements, 3(2), e00336-15. (doi: 10.1128/genomeA.00336-15) (PMID:25931597) (PMCID:PMC4417693)
Halai, M., Ker, A., Meek, R.M. D., Nadeem, D., Sjostrom, T., Su, B., McNamara, L. E., Dalby, M. J. and Young, P. S. (2014) Scanning electron microscopical observation of an osteoblast/osteoclast co-culture on micropatterned orthopaedic ceramics. Journal of Tissue Engineering, 5, (doi: 10.1177/2041731414552114) (PMID:25383174) (PMCID:PMC4221946)
McNamara, L. E., Sjostrom, T., Seunarine, K., Meek, R.M. D., Su, B. and Dalby, M. J. (2014) Investigation of the limits of nanoscale filopodial interactions. Journal of Tissue Engineering, 5, p. 2041731414536177. (doi: 10.1177/2041731414536177) (PMID:24904726) (PMCID:PMC4046805)
Yang, J., McNamara, L. E., Gadegaard, N. , Alakpa, E. V., Burgess, K. V., Meek, D. and Dalby, M. J. (2014) Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs. ACS Nano, 8(10), pp. 9941-9953. (doi: 10.1021/nn504767g) (PMID:25227207)
Maclaine, S.E., Gadhari, N., Pugin, R., Meek, R.M.D., Liley, M. and Dalby, M.J. (2012) Optimizing the osteogenicity of nanotopography using block co-polymer phase separation fabrication techniques. Journal of Orthopaedic Research, 30(8), pp. 1190-1197. (doi: 10.1002/jor.22076)
McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)
Wilkinson, A., Hewitt, R. N., McNamara, L. E., McCloy, D., Meek, R.M. D. and Dalby, M. J. (2011) Biomimetic microtopography to enhance osteogenesis in vitro. Acta Biomaterialia, 7(7), pp. 2919-2925. (doi: 10.1016/j.actbio.2011.03.026)
Ogunwale, B., Schmidt-Ott, A., Meek, R. M. D. and Brewer, J. M. (2009) Investigating the immunologic effects of CoCr nanoparticles. Clinical Orthopaedics and Related Research, 467(11), 3010. (doi: 10.1007/s11999-009-0949-9) (PMID:19565304) (PMCID:PMC2758989)
Research datasets
2021
Kennedy, J., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P., Reid, S., Young, P., Meek, D., Goodyear, C. and Dalby, M. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. [Data Collection]
2016
Lee, L., Gadegaard, N. , Andrés, M. C. d., Turner, L.-A., Burgess, K., Yarwood, S., Wells, J., Mpoyi, E., Salmerón-Sánchez, M., Meek, R. D., Oreffo, R. and Dalby, M. (2016) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. [Data Collection] (Unpublished)