2023

Nguyen, T.-H. , Silva-Alvim, F. A. L., Hills, A. and Blatt, M. R. (2023) OnGuard3e: a predictive, ecophysiology‐ready tool for gas exchange and photosynthesis research. Plant, Cell and Environment, 46(11), pp. 3644-3658. (doi: 10.1111/pce.14674) (PMID:37498151)

2022

Horaruang, W. et al. (2022) Engineering a K+ channel 'sensory antenna' enhances stomatal kinetics, water use efficiency and photosynthesis. Nature Plants, 8(11), pp. 1262-1274. (doi: 10.1038/s41477-022-01255-2) (PMID:36266492)

Blatt, M. R. , Jezek, M., Lew, V. L. and Hills, A. (2022) What can mechanistic models tell us about guard cells, photosynthesis, and water use efficiency? Trends in Plant Science, 27(2), pp. 166-179. (doi: 10.1016/j.tplants.2021.08.010) (PMID:34565672)

2021

Jezek, M. et al. (2021) Guard cell endomembrane Ca2+-ATPases underpin a ‘carbon memory’ of photosynthetic assimilation that impacts on water-use efficiency. Nature Plants, 7(9), pp. 1301-1313. (doi: 10.1038/s41477-021-00966-2) (PMID:34326530)

2020

Jezek, M., Hills, A., Blatt, M. R. and Lew, V. L. (2020) A constraint-relaxation-recovery mechanism for stomatal dynamics. Plant, Cell and Environment, 42(8), pp. 2399-2410. (doi: 10.1111/pce.13568) (PMID:31032976) (PMCID:PMC6771799)

Klejchová, M., Hills, A. and Blatt, M. R. (2020) Predicting the unexpected in stomatal gas exchange: not just an open-and-shut case. Biochemical Society Transactions, 48(3), pp. 881-889. (doi: 10.1042/BST20190632) (PMID:32453378) (PMCID:PMC7329339)

Horaruang, W., Hills, A. and Blatt, M. R. (2020) Communication between the plasma membrane and tonoplast is an emergent property of ion transport. Plant Physiology, 182, pp. 1833-1835. (doi: 10.1104/pp.19.01485) (PMID:31988199)

2018

Shahzad, Z., Kellermeier, F., Armstrong, E. M., Rogers, S. , Lobet, G., Amtmann, A. and Hills, A. (2018) EZ-Root-VIS: A software pipeline for the rapid analysis and visual reconstruction of root system architecture. Plant Physiology, 177(4), pp. 1368-1381. (doi: 10.1104/pp.18.00217) (PMID:29895611)

Hills, A. and Volkov, V. (2018) Electrophysiology equipment and software. In: Roberts, J. (ed.) Annual Plant Reviews. John Wiley & Sons, Ltd, pp. 44-77. ISBN 9781119312994 (doi: 10.1002/9781119312994.apr0142)

2017

Wang, Y., Hills, A., Vialet-Chabrand, S., Papanatsiou, M., Griffiths, H., Rogers, S. , Lawson, T., Lew, V. L. and Blatt, M. R. (2017) Unexpected connections between humidity and ion transport discovered using a model to bridge guard cell-to-leaf scales. Plant Cell, 29(11), pp. 2921-2939. (doi: 10.1105/tpc.17.00694) (PMID:29093213)

Cai, S. et al. (2017) Evolutionary conservation of ABA signaling for stomatal closure in ferns. Plant Physiology, 174(2), pp. 732-747. (doi: 10.1104/pp.16.01848) (PMID:28232585)

Vialet-Chabrand, S., Hills, A., Wang, Y., Griffiths, H., Lew, V. L., Lawson, T., Blatt, M. R. and Rogers, S. (2017) Global sensitivity analysis of OnGuard models identifies key hubs for transport interaction in stomatal dynamics. Plant Physiology, 174(2), pp. 680-688. (doi: 10.1104/pp.17.00170) (PMID:28432256)

Chen, Z.-H., Chen, G., Dai, F., Wang, Y., Hills, A., Ruan, Y.-L., Zhang, G., Franks, P. J., Nevo, E. and Blatt, M. R. (2017) Molecular evolution of grass stomata. Trends in Plant Science, 22(2), pp. 124-139. (doi: 10.1016/j.tplants.2016.09.005) (PMID:27776931)

2016

Vialet-Chabrand, S., Matthews, J. S. A., Brendel, O., Blatt, M.R. , Wang, Y., Hills, A., Griffiths, H., Rogers, S. and Lawson, T. (2016) Modelling water use efficiency in a dynamic environment: an example using Arabidopsis thaliana. Plant Science, 251, pp. 65-74. (doi: 10.1016/j.plantsci.2016.06.016) (PMID:27593464) (PMCID:PMC5038844)

Chen, Z.-H. et al. (2016) Nitrate reductase mutation alters potassium nutrition as well as nitric oxide-mediated control of guard cell ion channels in Arabidopsis. New Phytologist, 209(4), pp. 1456-1469. (doi: 10.1111/nph.13714) (PMID:26508536)

Minguet-Parramona, C., Wang, Y., Hills, A., Vialet-Chabrand, S., Griffiths, H., Rogers, S., Lawson, T., Lew, V. L. and Blatt, M. R. (2016) An optimal frequency in Ca2+ oscillations for stomatal closure is an emergent property of ion transport in guard cells. Plant Physiology, 170(1), pp. 33-42. (doi: 10.1104/pp.15.01607) (PMID:26628748) (PMCID:PMC4704601)

2015

Grefen, C., Karnik, R. , Larson, E., Lefoulon, C., Wang, Y., Waghmare, S. , Zhang, B. , Hills, A. and Blatt, M. R. (2015) A vesicle-trafficking protein commandeers Kv channel voltage sensors for voltage-dependent secretion. Nature Plants, 1, 15108. (doi: 10.1038/nplants.2015.108)

2014

Blatt, M. R. , Wang, Y., Leonhardt, N. and Hills, A. (2014) Exploring emergent properties in cellular homeostasis using OnGuard to model K+ and other ion transport in guard cells. Journal of Plant Physiology, 171(9), pp. 770-778. (doi: 10.1016/j.jplph.2013.09.014) (PMID:24268743) (PMCID:PMC4030602)

Wang, Y., Hills, A. and Blatt, M. (2014) Systems analysis of guard cell membrane transport for enhanced stomatal dynamics and water use efficiency. Plant Physiology, 164(4), pp. 1593-1599. (doi: 10.1104/pp.113.233403) (PMID:24596330)

2013

Wang, Y., Chen, Z., Zhang, B. , Hills, A. and Blatt, M. R. (2013) PYR/PYL/RCAR abscisic acid receptors regulate K⁺ and Cl^- channels through reactive oxygen species-mediated activation of Ca²⁺ channels at the plasma membrane of intact Arabidopsis guard cells. Plant Physiology, 163(2), pp. 566-577. (doi: 10.1104/pp.113.219758) (PMID:23899646)

Blatt, M. R. , Hills, A., Chen, Z./H., Wang, Y., Papanatsiou, M. and Lew, V. L. (2013) The conceptual approach to quantitative modeling of guard cells. Plant Signaling and Behavior, 8(1), e22747. (doi: 10.4161/psb.22747)

2012

Wang, Y., Papanatsiou, M., Eisenach, C., Karnik, R. , Williams, M., Hills, A., Lew, V.L. and Blatt, M.R. (2012) Systems dynamic modeling of a guard cell Cl- channel mutant uncovers an emergent homeostatic network regulating stomatal transpiration. Plant Physiology, 160(4), pp. 1956-1967. (doi: 10.1104/pp.112.207704)

Chen, Z.-H., Eisenach, C., Xu, X.Q., Hills, A. and Blatt, M.R. (2012) Protocol: optimised electrophyiological analysis of intact guard cells from arabidopsis. Plant Methods, 8(15), (doi: 10.1186/1746-4811-8-15)

Chen, Z.-H., Hills, A., Batz, U., Amtmann, A. , Lew, V.L. and Blatt, M.R. (2012) Systems dynamic modeling of the stomatal guard cell predicts emergent behaviors in transport, signaling, and volume control. Plant Physiology, 159(3), pp. 1235-1251. (doi: 10.1104/pp.112.197350)

Hills, A., Chen, Z.-H., Amtmann, A. , Blatt, M.R. and Lew, V.L. (2012) OnGuard, a computational platform for quantitative kinetic modeling of guard cell physiology. Plant Physiology, 159(3), pp. 1026-1042.

2011

Chen, Z., Grefen, C., Donald, N., Hills, A. and Blatt, M.R. (2011) A bicistronic, Ubiquitin-10 promoter-based vector cassette for transient transformation and functional analysis of membrane transport demonstrates the utility of quantitative voltage clamp studies on intact Arabidopsis root epidermis. Plant, Cell and Environment, 34(4), pp. 554-564. (doi: 10.1111/j.1365-3040.2010.02262.x) (PMID:21251017)

2010

Garcia-Mata, C., Wang, J., Gajdanowicz, P., Gonzalez, W., Hills, A., Donald, N., Riedelsberger, J., Amtmann, A. , Dreyer, I. and Blatt, M.R. (2010) A minimal cysteine motif required to activate the SKOR K+ channel of arabidopsis by the reactive oxygen species H2O2. Journal of Biological Chemistry, 285(38), pp. 29286-29294. (doi: 10.1074/jbc.M110.141176) (PMID:20605786) (PMCID:PMC2937961)

Grefen, C., Chen, Z., Honsbein, A., Donald, N., Hills, A. and Blatt, M.R. (2010) A novel motif essential for SNARE interaction with the K+ channel KC1 and channel gating in Arabidopsis. Plant Cell, 22(9), pp. 3076-3092. (doi: 10.1105/tpc.110.077768)

Chen, Z.-H., Hills, A., Lim, C.K. and Blatt, M.R. (2010) Dynamic regulation of guard cell anion channels by cytosolic-free Ca²⁺ concentration and protein phosphorylation. Plant Journal, 61(5), pp. 816-825. (doi: 10.1111/j.1365-313X.2009.04108.x) (PMID:20015065)

2009

Armengaud, P., Zambaux, K., Hills, A., Sulpice, R., Pattison, R. J., Blatt, M. R. and Amtmann, A. (2009) EZ-Rhizo: integrated software for the fast and accurate measurement of root system architecture. Plant Journal, 57(5), pp. 945-956. (doi: 10.1111/j.1365-313X.2008.03739.x)

2008

Sokolovski, S., Hills, A., Gay, R. A. and Blatt, M. R. (2008) Functional interaction of the SNARE protein NtSyp121 in Ca2+ channel gating, Ca2+ transients and ABA signalling of stomatal guard cells. Molecular Plant, 1(2), pp. 347-358. (doi: 10.1093/mp/ssm029) (PMID:19825544)

Articles

Nguyen, T.-H. , Silva-Alvim, F. A. L., Hills, A. and Blatt, M. R. (2023) OnGuard3e: a predictive, ecophysiology‐ready tool for gas exchange and photosynthesis research. Plant, Cell and Environment, 46(11), pp. 3644-3658. (doi: 10.1111/pce.14674) (PMID:37498151)

Horaruang, W. et al. (2022) Engineering a K+ channel 'sensory antenna' enhances stomatal kinetics, water use efficiency and photosynthesis. Nature Plants, 8(11), pp. 1262-1274. (doi: 10.1038/s41477-022-01255-2) (PMID:36266492)

Blatt, M. R. , Jezek, M., Lew, V. L. and Hills, A. (2022) What can mechanistic models tell us about guard cells, photosynthesis, and water use efficiency? Trends in Plant Science, 27(2), pp. 166-179. (doi: 10.1016/j.tplants.2021.08.010) (PMID:34565672)

Jezek, M. et al. (2021) Guard cell endomembrane Ca2+-ATPases underpin a ‘carbon memory’ of photosynthetic assimilation that impacts on water-use efficiency. Nature Plants, 7(9), pp. 1301-1313. (doi: 10.1038/s41477-021-00966-2) (PMID:34326530)

Jezek, M., Hills, A., Blatt, M. R. and Lew, V. L. (2020) A constraint-relaxation-recovery mechanism for stomatal dynamics. Plant, Cell and Environment, 42(8), pp. 2399-2410. (doi: 10.1111/pce.13568) (PMID:31032976) (PMCID:PMC6771799)

Klejchová, M., Hills, A. and Blatt, M. R. (2020) Predicting the unexpected in stomatal gas exchange: not just an open-and-shut case. Biochemical Society Transactions, 48(3), pp. 881-889. (doi: 10.1042/BST20190632) (PMID:32453378) (PMCID:PMC7329339)

Horaruang, W., Hills, A. and Blatt, M. R. (2020) Communication between the plasma membrane and tonoplast is an emergent property of ion transport. Plant Physiology, 182, pp. 1833-1835. (doi: 10.1104/pp.19.01485) (PMID:31988199)

Shahzad, Z., Kellermeier, F., Armstrong, E. M., Rogers, S. , Lobet, G., Amtmann, A. and Hills, A. (2018) EZ-Root-VIS: A software pipeline for the rapid analysis and visual reconstruction of root system architecture. Plant Physiology, 177(4), pp. 1368-1381. (doi: 10.1104/pp.18.00217) (PMID:29895611)

Wang, Y., Hills, A., Vialet-Chabrand, S., Papanatsiou, M., Griffiths, H., Rogers, S. , Lawson, T., Lew, V. L. and Blatt, M. R. (2017) Unexpected connections between humidity and ion transport discovered using a model to bridge guard cell-to-leaf scales. Plant Cell, 29(11), pp. 2921-2939. (doi: 10.1105/tpc.17.00694) (PMID:29093213)

Cai, S. et al. (2017) Evolutionary conservation of ABA signaling for stomatal closure in ferns. Plant Physiology, 174(2), pp. 732-747. (doi: 10.1104/pp.16.01848) (PMID:28232585)

Vialet-Chabrand, S., Hills, A., Wang, Y., Griffiths, H., Lew, V. L., Lawson, T., Blatt, M. R. and Rogers, S. (2017) Global sensitivity analysis of OnGuard models identifies key hubs for transport interaction in stomatal dynamics. Plant Physiology, 174(2), pp. 680-688. (doi: 10.1104/pp.17.00170) (PMID:28432256)

Chen, Z.-H., Chen, G., Dai, F., Wang, Y., Hills, A., Ruan, Y.-L., Zhang, G., Franks, P. J., Nevo, E. and Blatt, M. R. (2017) Molecular evolution of grass stomata. Trends in Plant Science, 22(2), pp. 124-139. (doi: 10.1016/j.tplants.2016.09.005) (PMID:27776931)

Vialet-Chabrand, S., Matthews, J. S. A., Brendel, O., Blatt, M.R. , Wang, Y., Hills, A., Griffiths, H., Rogers, S. and Lawson, T. (2016) Modelling water use efficiency in a dynamic environment: an example using Arabidopsis thaliana. Plant Science, 251, pp. 65-74. (doi: 10.1016/j.plantsci.2016.06.016) (PMID:27593464) (PMCID:PMC5038844)

Chen, Z.-H. et al. (2016) Nitrate reductase mutation alters potassium nutrition as well as nitric oxide-mediated control of guard cell ion channels in Arabidopsis. New Phytologist, 209(4), pp. 1456-1469. (doi: 10.1111/nph.13714) (PMID:26508536)

Minguet-Parramona, C., Wang, Y., Hills, A., Vialet-Chabrand, S., Griffiths, H., Rogers, S., Lawson, T., Lew, V. L. and Blatt, M. R. (2016) An optimal frequency in Ca2+ oscillations for stomatal closure is an emergent property of ion transport in guard cells. Plant Physiology, 170(1), pp. 33-42. (doi: 10.1104/pp.15.01607) (PMID:26628748) (PMCID:PMC4704601)

Grefen, C., Karnik, R. , Larson, E., Lefoulon, C., Wang, Y., Waghmare, S. , Zhang, B. , Hills, A. and Blatt, M. R. (2015) A vesicle-trafficking protein commandeers Kv channel voltage sensors for voltage-dependent secretion. Nature Plants, 1, 15108. (doi: 10.1038/nplants.2015.108)

Blatt, M. R. , Wang, Y., Leonhardt, N. and Hills, A. (2014) Exploring emergent properties in cellular homeostasis using OnGuard to model K+ and other ion transport in guard cells. Journal of Plant Physiology, 171(9), pp. 770-778. (doi: 10.1016/j.jplph.2013.09.014) (PMID:24268743) (PMCID:PMC4030602)

Wang, Y., Hills, A. and Blatt, M. (2014) Systems analysis of guard cell membrane transport for enhanced stomatal dynamics and water use efficiency. Plant Physiology, 164(4), pp. 1593-1599. (doi: 10.1104/pp.113.233403) (PMID:24596330)

Wang, Y., Chen, Z., Zhang, B. , Hills, A. and Blatt, M. R. (2013) PYR/PYL/RCAR abscisic acid receptors regulate K⁺ and Cl^- channels through reactive oxygen species-mediated activation of Ca²⁺ channels at the plasma membrane of intact Arabidopsis guard cells. Plant Physiology, 163(2), pp. 566-577. (doi: 10.1104/pp.113.219758) (PMID:23899646)

Blatt, M. R. , Hills, A., Chen, Z./H., Wang, Y., Papanatsiou, M. and Lew, V. L. (2013) The conceptual approach to quantitative modeling of guard cells. Plant Signaling and Behavior, 8(1), e22747. (doi: 10.4161/psb.22747)

Wang, Y., Papanatsiou, M., Eisenach, C., Karnik, R. , Williams, M., Hills, A., Lew, V.L. and Blatt, M.R. (2012) Systems dynamic modeling of a guard cell Cl- channel mutant uncovers an emergent homeostatic network regulating stomatal transpiration. Plant Physiology, 160(4), pp. 1956-1967. (doi: 10.1104/pp.112.207704)

Chen, Z.-H., Eisenach, C., Xu, X.Q., Hills, A. and Blatt, M.R. (2012) Protocol: optimised electrophyiological analysis of intact guard cells from arabidopsis. Plant Methods, 8(15), (doi: 10.1186/1746-4811-8-15)

Chen, Z.-H., Hills, A., Batz, U., Amtmann, A. , Lew, V.L. and Blatt, M.R. (2012) Systems dynamic modeling of the stomatal guard cell predicts emergent behaviors in transport, signaling, and volume control. Plant Physiology, 159(3), pp. 1235-1251. (doi: 10.1104/pp.112.197350)

Hills, A., Chen, Z.-H., Amtmann, A. , Blatt, M.R. and Lew, V.L. (2012) OnGuard, a computational platform for quantitative kinetic modeling of guard cell physiology. Plant Physiology, 159(3), pp. 1026-1042.

Chen, Z., Grefen, C., Donald, N., Hills, A. and Blatt, M.R. (2011) A bicistronic, Ubiquitin-10 promoter-based vector cassette for transient transformation and functional analysis of membrane transport demonstrates the utility of quantitative voltage clamp studies on intact Arabidopsis root epidermis. Plant, Cell and Environment, 34(4), pp. 554-564. (doi: 10.1111/j.1365-3040.2010.02262.x) (PMID:21251017)

Garcia-Mata, C., Wang, J., Gajdanowicz, P., Gonzalez, W., Hills, A., Donald, N., Riedelsberger, J., Amtmann, A. , Dreyer, I. and Blatt, M.R. (2010) A minimal cysteine motif required to activate the SKOR K+ channel of arabidopsis by the reactive oxygen species H2O2. Journal of Biological Chemistry, 285(38), pp. 29286-29294. (doi: 10.1074/jbc.M110.141176) (PMID:20605786) (PMCID:PMC2937961)

Grefen, C., Chen, Z., Honsbein, A., Donald, N., Hills, A. and Blatt, M.R. (2010) A novel motif essential for SNARE interaction with the K+ channel KC1 and channel gating in Arabidopsis. Plant Cell, 22(9), pp. 3076-3092. (doi: 10.1105/tpc.110.077768)

Chen, Z.-H., Hills, A., Lim, C.K. and Blatt, M.R. (2010) Dynamic regulation of guard cell anion channels by cytosolic-free Ca²⁺ concentration and protein phosphorylation. Plant Journal, 61(5), pp. 816-825. (doi: 10.1111/j.1365-313X.2009.04108.x) (PMID:20015065)

Armengaud, P., Zambaux, K., Hills, A., Sulpice, R., Pattison, R. J., Blatt, M. R. and Amtmann, A. (2009) EZ-Rhizo: integrated software for the fast and accurate measurement of root system architecture. Plant Journal, 57(5), pp. 945-956. (doi: 10.1111/j.1365-313X.2008.03739.x)

Sokolovski, S., Hills, A., Gay, R. A. and Blatt, M. R. (2008) Functional interaction of the SNARE protein NtSyp121 in Ca2+ channel gating, Ca2+ transients and ABA signalling of stomatal guard cells. Molecular Plant, 1(2), pp. 347-358. (doi: 10.1093/mp/ssm029) (PMID:19825544)

Book Sections

Hills, A. and Volkov, V. (2018) Electrophysiology equipment and software. In: Roberts, J. (ed.) Annual Plant Reviews. John Wiley & Sons, Ltd, pp. 44-77. ISBN 9781119312994 (doi: 10.1002/9781119312994.apr0142)