School of Molecular Biosciences

Hwej, A., Al-Ferjani, A., Alshuweishi, Y., Naji, A., Kennedy, S., Salt, I. (2024) Lack of AMP-activated protein kinase-α1 reduces nitric oxide synthesis in thoracic aorta perivascular adipose tissue. Vascular Pharmacology, 157, (doi: 10.1016/j.vph.2024.107437)

Selman, C. (2024) The dietary exposome: a brief history of diet, longevity and age-related health in rodents. Clinical Science, 138, pp. 1343-1356. (doi: 10.1042/CS20241248)

Salt, I. P., Carling, D. (2024) A special issue of Essays in Biochemistry on AMPK and AMPK-related kinases. Essays In Biochemistry,

Dearlove, E. L., Chatrin, C., Buetow, L., Ahmed, S. F., Schmidt, T., Bushell, M., Smith, B. O., Huang, D. T. (2024) DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids. eLife, 13, (doi: 10.7554/elife.98070)

Ibrahim, R., Dobson, A., Bahilo Martinez, M. (2024) Rapamycin’s lifespan effect is modulated by mito-nuclear epistasis in Drosophila. Aging Cell, (doi: 10.1111/acel.14328)

Battle, M. W., Ewing, S. F., Dickson, C., Obaje, J., Edgeworth, K. N., Bindbeutel, R., Antoniou Kourounioti, R. L., Nusinow, D. A.,, Jones, M. A. (2024) Manipulation of photosensory and circadian signalling restricts phenotypic plasticity in response to changing environmental conditions in Arabidopsis. Molecular Plant, 17, pp. 1458-1471. (doi: 10.1016/j.molp.2024.07.007)

Borland, G., Wilkie, S. E., Thomson, J., Wang, Z., Tullett, J. M.A., Alic, N., Selman, C. (2024) Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan. Aging Cell, 23, (doi: 10.1111/acel.14141)

Tokatlidis, K. (2024) MIMAS is a new giant multifunctional player in the mitochondrial megacomplex playground. Cell Reports, 43, (doi: 10.1016/j.celrep.2024.113874)

Pal, S., Nare, Z., Rao, V. A., Smith, B. O., Morrison, I., Fitzgerald, E. A., Scott, A., Bingham, M. J., Pesnot, T. (2024) Accelerating BRPF1b hit identification with BioPhysical and Active Learning Screening (BioPALS) ChemMedChem, 19, (doi: 10.1002/cmdc.202300590)

Harnett, M. M., Doonan, J., Tarafdar, A., Pineda, M., Duncombe-Moore, J., Buitrago, G., Pan, P., Hoskisson, P., Selman, C., Harnett, W. (2024) The parasitic worm product ES-62 protects against collagen-induced arthritis by resetting the gut-bone marrow axis in a microbiome-dependent manner. Frontiers in Tropical Diseases, 4, (doi: 10.3389/fitd.2023.1334705)

Neytchev, O., Erlandsson, H., Witasp, A., Nordfors, L., Qureshi, A. R., Iseri, K., Morohoshi, H., Selman, C., Ebert, T., Kublickiene, K., Stenvinkel, P., Shiels, P. G. (2023) Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageing. Journal of Internal Medicine, 295, pp. 79-90. (doi: 10.1111/joim.13724)

Gould, E. et al. (2023) Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology. EcoEvoRxiv, (doi: 10.32942/X2GG62)

Irshad, Z., Lund, J., Sillars, A., Løvsletten, N. G., Gharanei, S., Salt, I. P., Freeman, D. J., Gill, J. M.R., Thoresen, G. H., Rustan, A. C., Zammit, V. A. (2023) The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho-physiological background. FASEB Journal, 37, (doi: 10.1096/fj.202300960RR)

Sannino, D. R., Dobson, A. J. (2023) Acetobacter pomorum in the Drosophila gut microbiota buffers against host metabolic impacts of dietary preservative formula and batch variation in dietary yeast. Applied and Environmental Microbiology, 89, (doi: 10.1128/aem.00165-23)

James, A. B., Sharples, C., Laird, J., Armstrong, E. M., Guo, W., Tzioutziou, N., Zhang, R., Brown, J. W.S., Nimmo, H., Jones, M. (2023) REVEILLE2 thermosensitive splicing: a molecular basis for the integration of nocturnal temperature information by the Arabidopsis circadian clock. New Phytologist, (doi: 10.1111/nph.19339)

Prasetyaningrum, P., Litthauer, S., Vegliani, F., Battle, M. W., Wood, M. W., Liu, X., Dickson, C., Jones, M. A. (2023) Inhibition of RNA degradation integrates the metabolic signals induced by osmotic stress into the Arabidopsis circadian system. Journal of Experimental Botany, 74, pp. 5805-5819. (doi: 10.1093/jxb/erad274)

Dobson, A., Voigt, S., Kumpitsch, L., Langer, L., Voigt, E., Ibrahim, R., Dowling, D., Reinhardt, K. (2023) Mitonuclear interactions shape both direct and parental effects of diet on fitness, and involve a SNP in mitoribosomal 16s rRNA. PLoS Biology, 21, (doi: 10.1371/journal.pbio.3002218)

Dowsett, L., Duluc, L., Higgins, E., Alghamdi, F., Fast, W., Salt, I. P., Leiper, J. (2023) Asymmetric dimethylarginine positively modulates calcium-sensing receptor signalling to promote lipid accumulation. Cellular Signalling, 107, (doi: 10.1016/j.cellsig.2023.110676)

Panagiotou, N., McGuinness, D., Jaminon, A. M.G., Mees, B., Selman, C., Schurgers, L., Shiels, P. G. (2023) Microvesicle-mediated tissue regeneration mitigates the effects of cellular ageing. Cells, 12, (doi: 10.3390/cells12131707)

Wilkie, S. E., Marcu, D. E., Carter, R. N., Morton, N. M., Gonzalo, S., Selman, C. (2023) Hepatic hydrogen sulfide levels are reduced in mouse model of Hutchinson-Gilford progeria syndrome. Aging, 15, pp. 5266-5278. (doi: 10.18632/aging.204835)

Trovato, M., Brini, F., Mseddi, K., Rhizopoulou, S., Jones, M. A. (2023) A holistic and sustainable approach linked to drought tolerance of Mediterranean crops. Frontiers in Plant Science, 14, (doi: 10.3389/fpls.2023.1167376)

Hamilton, K. L., Selman, C. (2023) Can exercise prevent the age‐related decline in adaptive homeostasis? Evidence across organisms and tissues. Journal of Physiology, 601, pp. 2053-2056. (doi: 10.1113/JP284583)

Salmon, P., Dawson, N. J., Millet, C., Selman, C., Monaghan, P. (2023) Mitochondrial function declines with age within individuals but is not linked to the pattern of growth or mortality risk in zebra finch. Aging Cell, 22, (doi: 10.1111/acel.13822)

Vitale, M., Sanz, A., Scialò, F. (2023) Mitochondrial redox signaling: a key player in aging and disease. Aging, (doi: 10.18632/aging.204659)

Castejon-Vega, B., Cordero, M. D., Sanz, A. (2023) How the disruption of mitochondrial redox signalling contributes to ageing. Antioxidants, 12, (doi: 10.3390/antiox12040831)

Adam, S., Zheng, D., Klein, A., Volz, C., Mullen, W., Shirran, S. L., Smith, B. O., Kalinina, O. V., Müller, R., Koehnke, J. (2023) Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis. Nature Chemistry, 15, pp. 560-568. (doi: 10.1038/s41557-023-01153-w)

Salmón, P., Millet, C., Selman, C., Monaghan, P., Dawson, N. J. (2023) Tissue-specific reductions in mitochondrial efficiency and increased ROS release rates during ageing in zebra finches, Taeniopygia guttata. GeroScience, 45, pp. 256-276. (doi: 10.1007/s11357-022-00624-1)

Queiroz, M. V., Battle, M. W., Jones, M. A. (2023) Interactions between photosynthesis and the circadian system. Burleigh Dodds Science Publishing

Kowalczyk, D., Nakasone, M. A., Smith, B. O., Huang, D. T. (2022) Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function. Life Science Alliance, 5, (doi: 10.26508/lsa.202201472)

Martínez Corrales, G., Li, M., Svermova, T., Goncalves, A., Voicu, D., Dobson, A. J., Southall, T. D., Alic, N. (2022) Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodelling and Xbp1. Nature Aging, 2, pp. 1176-1190. (doi: 10.1038/s43587-022-00312-x)

Kataura, T. et al. (2022) Autophagy promotes cell survival by maintaining NAD levels. Developmental Cell, 57, pp. 2584-2598.e11. (doi: 10.1016/j.devcel.2022.10.008)

Teige, M., Jones, M., Toledo-Ortiz, G. (2022) Plant organellar signalling—back and forth and intertwined with cellular signalling. Journal of Experimental Botany, 73, pp. 7103-7104. (doi: 10.1093/jxb/erac383)

Gracie, J., Zamberlan, F., Andrews, I. B., Smith, B. O., Peveler, W. J. (2022) Growth of plasmonic nanoparticles for aging cask-matured whisky. ACS Applied Nano Materials, 5, pp. 15362-15368. (doi: 10.1021/acsanm.2c03406)

Ryan, S. M., Ruscher, R., Johnston, W. A., Pickering, D. A., Kennedy, M. W., Smith, B. O., Jones, L., Buitrago, G., Field, M. A., Esterman, A. J., McHugh, C. P., Browne, D. J., Cooper, M. M., Ryan, R. Y. M., Doolan, D. L., Engwerda, C. R., Miles, K., Mitreva, M., Croese, J., Rahman, T., Alexandrov, K., Giacomin, P. R., Loukas, A. (2022) Novel antiinflammatory biologics shaped by parasite–host coevolution. Proceedings of the National Academy of Sciences of the United States of America, 119, (doi: 10.1073/pnas.2202795119)

Harnett, M. M., Doonan, J., Lumb, F. E., Crowe, J., Damink, R. O., Buitrago, G., Duncombe-Moore, J., Wilkinson, D. I., Suckling, C. J., Selman, C., Harnett, W. (2022) The parasitic worm product ES-62 protects the osteoimmunology axis in a mouse model of obesity-accelerated ageing. Frontiers in Immunology, 13, (doi: 10.3389/fimmu.2022.953053)

Caccavale, E., Johnson, M. P., Brijbassi, S., Andreazza, A. C., Tokatlidis, K. (2022) Mitochondria and Us: from exploration to global collective. Biochemist, 44, pp. 22-28. (doi: 10.1042/bio_2022_122)

Graham, C., Stefanatos, R., Yek, A. E.H., Spriggs, R. V., Loh, S. H.Y., Huerta Uribe, A., Zhang, T., Martins, L. M., Maddocks, O. D.K., Scialo, F., Sanz, A. (2022) Mitochondrial ROS signalling requires uninterrupted electron flow and is lost during ageing in flies. GeroScience, 44, pp. 1961-1974. (doi: 10.1007/s11357-022-00555-x)

Kjeldsen, A., Kay, J. E., Baxter, S., McColm, S., Serrano-Amatriain, C., Parker, S., Robb, E., Arnold, S. A., Gilmour, C., Raper, A., Robertson, G., Fleming, R., Smith, B. O., Fotheringham, I. G., Christie, J. M., Magneschi, L. (2022) The fluorescent protein iLOV as a reporter for screening of high‐yield production of antimicrobial peptides in Pichia pastoris. Microbial Biotechnology, 15, pp. 2126-2139. (doi: 10.1111/1751-7915.14034)

Ledahawsky, L. M., Terzenidou, M. E., Edwards, R., Kline, R. A., Graham, L. C., Eaton, S. L., van der Hoorn, D., Chaytow, H., Huang, Y.‐T., Groen, E. J.N., Motyl, A. A. L., Lamont, D. J., Tokatlidis, K., Wishart, T. M., Gillingwater, T. H. (2022) The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo. FEBS Journal, 289, pp. 3894-3914. (doi: 10.1111/febs.16377)

Dawson, N. J., Millet, C., Selman, C., Metcalfe, N. B. (2022) Inter-individual variation in mitochondrial phosphorylation efficiency predicts growth rates in ectotherms at high temperatures. FASEB Journal, 36, (doi: 10.1096/fj.202101806RR)

de Carbonnel, M., Stormonth-Darling, J. M., Liu, W., Kuziak, D., Jones, M. A. (2022) Realising the environmental potential of vertical farming systems through advances in plant photobiology. Biology, 11, (doi: 10.3390/biology11060922)

Torres Cabán, C. C., Yang, M., Lai, C., Yang, L., Subach, F. V., Smith, B. O., Piatkevich, K. D., Boyden, E. S. (2022) Tuning the sensitivity of genetically encoded fluorescent potassium indicators through structure-guided and genome mining strategies. ACS Sensors, 7, pp. 1336-1346. (doi: 10.1021/acssensors.1c02201)

Tibbo, A. J., Mika, D., Dobi, S., Ling, J., McFall, A., Tejeda, G. S., Blair, C., MacLeod, R., MacQuaide, N., Gök, C., Fuller, W., Smith, B. O., Smith, G. L., Vandecasteele, G., Brand, T., Baillie, G. S. (2022) Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins. Journal of Molecular and Cellular Cardiology, 165, pp. 86-102. (doi: 10.1016/j.yjmcc.2022.01.001)

Javidnia, S., Cranwell, S., Mueller, S. H., Selman, C., Tullet, J. M.A., Kuchenbaecker, K., Alic, N. (2022) Mendelian randomization analyses implicate biogenesis of translation machinery in human aging. Genome Research, 32, pp. 258-265. (doi: 10.1101/gr.275636.121)

Nakasone, M. A., Majorek, K. A., Gabrielsen, M., Sibbet, G. J., Smith, B. O., Huang, D. T. (2022) Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension. Nature Chemical Biology, 18, pp. 422-431. (doi: 10.1038/s41589-021-00952-x)

Neckebroeck, A., Kelly, S. M., Smith, B. O., Clark, J. S. (2022) Synthesis of the prototypical cyclopropyl dipeptide mimic and evaluation of its turn-inducing capability. Journal of Organic Chemistry, 87, pp. 258-270. (doi: 10.1021/acs.joc.1c02344)

Tokatlidis, K., Eaglesfield, R. (2021) Targeting and insertion of membrane proteins in mitochondria. Frontiers in Cell and Developmental Biology, 9, (doi: 10.3389/fcell.2021.803205)

Carter, R. N. et al. (2021) The hepatic compensatory response to elevated systemic sulfide promotes diabetes. Cell Reports, 37, (doi: 10.1016/j.celrep.2021.109958)

Castejón-Vega, B., Rubio, A., Pérez-Pulido, A. J., Quiles, J. L., Lane, J. D., Fernández-Domínguez, B., Cachón-González, M. B., Martín-Ruiz, C., Sanz, A., Cox, T. M., Alcocer-Gómez, E., Cordero, M. D. (2021) L-arginine ameliorates defective autophagy in GM2 gangliosidoses by mTOR modulation. Cells, 10, (doi: 10.3390/cells10113122)

Wilkie, S. E., Borland, G., Carter, R. N., Morton, N. M., Selman, C. (2021) Hydrogen sulfide in ageing, longevity and disease. Biochemical Journal, 478, pp. 3485-3504. (doi: 10.1042/BCJ20210517)

Prabhakar, A. T., James, C. D., Das, D., Otoa, R., Day, M., Burgner, J., Fontan, C. T., Wang, X., Wieland, A., Donaldson, M. M., Bristol, M. L., Li, R., Oliver, A. W., Pearl, L. H., Smith, B. O., Glass, S., Morgan, I. M. (2021) CK2 phosphorylation of human papillomavirus 16 E2 on serine 23 promotes interaction with TopBP1 and is critical for E2 interaction with mitotic chromatin and the viral life cycle. mBio, 12, (doi: 10.1128/mbio.01163-21)

Bonfini, A., Dobson, A. J., Duneau, D., Revah, J., Liu, X., Houtz, P., Buchon, N. (2021) Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size. eLife, 10, (doi: 10.7554/elife.64125)

Mulvey, L., Wilkie, S. E., Borland, G., Griffiths, K., Sinclair, A., McGuinness, D., Watson, D. G., Selman, C. (2021) Strain-specific metabolic responses to long-term caloric restriction in female ILSXISS recombinant inbred mice. Molecular and Cellular Endocrinology, 535, (doi: 10.1016/j.mce.2021.111376)

Buist, H. K., Luchowska-Stańska, U., van Basten, B., Valli, J., Smith, B. O., Baillie, G. S., Rickman, C., Ricketts, B., Davidson, A., Hannam, R., Sunderland, J., Yarwood, S. J. (2021) Identification and characterization of an affimer affinity reagent for the detection of the cAMP sensor, EPAC1. Cells, 10, (doi: 10.3390/cells10092307)

Geldon, S., Fernandez-Vizarra, E., Tokatlidis, K. (2021) Redox-mediated regulation of mitochondrial biogenesis, dynamics and respiratory chain assembly in yeast and human cells. Frontiers in Cell and Developmental Biology, 9, (doi: 10.3389/fcell.2021.720656)

Salmón, P., Millet, C., Selman, C., Monaghan, P. (2021) Growth acceleration results in faster telomere shortening later in life. Proceedings of the Royal Society of London Series B: Biological Sciences, 288, (doi: 10.1098/rspb.2021.1118)

Ahwazi, D., Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, A. S., Graesle, P., Alshuweishi, Y. A. I., Treebak, J. T., Salt, I., Göransson, O., Zeqiraj, E., Scott, J. W., Sakamoto, K. (2021) Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965. Biochemical Journal, 478, pp. 2977-2997. (doi: 10.1042/BCJ20210284)

Kulaberoglu, Y., Malik, Y., Borland, G., Selman, C., Alic, N., Tullet, J. M.A. (2021) RNA polymerase III, ageing and longevity. Frontiers in Genetics, 12, (doi: 10.3389/fgene.2021.705122)

Palmer, T. M., Salt, I. P. (2021) Nutrient regulation of inflammatory signalling in obesity and vascular disease. Clinical Science, 135, pp. 1563-1590. (doi: 10.1042/CS20190768)

Morgan, D. C., Morris, C., Mahindra, A., Blair, C. M., Tejeda, G., Herbert, I., Turnbull, M. L., Lieber, G., Willett, B. J., Logan, N., Smith, B., Tobin, A. B., Bhella, D., Baillie, G. S., Jamieson, A. G. (2021) Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalisation. Peptide Science, 113, (doi: 10.1002/pep2.24217)

Navas, P., Sanz, A. (2021) Editorial: "Mitochondrial Coenzyme Q Homeostasis: signalling, respiratory chain stability and diseases." Free Radical Biology and Medicine, 169, pp. 12-13. (doi: 10.1016/j.freeradbiomed.2021.04.005)

Stevens, J., Jones, M. A., Lawson, T. (2021) Diverse physiological and physical responses among wild, landrace and elite barley varieties point to novel breeding opportunities. Agronomy, 11, (doi: 10.3390/agronomy11050921)

Salt, I. P., Nunes, J. R.C., Fullerton, M. D. (2021) Metformin again? Atheroprotection mediated by macrophage AMPK and ATF1. Cardiovascular Research, 117, pp. 1233-1234. (doi: 10.1093/cvr/cvab065)

Edwards, R., Eaglesfield, R., Tokatlidis, K. (2021) The mitochondrial intermembrane space: the most constricted mitochondrial sub-compartment with the largest variety of protein import pathways. Open Biology, 11, (doi: 10.1098/rsob.210002)

Scialo, F., Sanz, A. (2021) Coenzyme Q redox signalling and longevity. Free Radical Biology and Medicine, 164, pp. 187-205. (doi: 10.1016/j.freeradbiomed.2021.01.018)

Kopietz, F., Alshuweishi, Y., Bijland, S., Alghamdi, F., Degerman, E., Sakamoto, K., Salt, I. P., Göransson, O. (2021) A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner. Biochemical Journal, 478, pp. 633-646. (doi: 10.1042/BCJ20200659)

Navarro-Pando, J. M., Alcocer-Gómez, E., Castejón-Vega, B., Navarro-Villarán, E., Condés-Hervás, M., Mundi-Roldan, M., Muntané, J., Pérez-Pulido, A. J., Bullon, P., Wang, C., Hoffman, H. M., Sanz, A., Mbalaviele, G., Ryffel, B., Cordero, M. D. (2021) Inhibition of the NLRP3 inflammasome prevents ovarian aging. Science Advances, 7, (doi: 10.1126/sciadv.abc7409)

Knuhtsen, A., Whiting, R., McWhinnie, F. S., Whitmore, C., Smith, B. O., Green, A. C., Timperley, C. M., Kinnear, K. I., Jamieson, A. G. (2021) μ-conotoxin KIIIA peptidomimetics that block human voltage-gated sodium channels. Peptide Science, 113, (doi: 10.1002/pep2.24203)

Klionsky, D. J. et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) Autophagy, 17, pp. 1-382. (doi: 10.1080/15548627.2020.1797280)

Dimogkioka, A.-R., Lees, J., Tokatlidis, K., Lacko, E. (2021) Protein import in mitochondria biogenesis: Guided by targeting signals and sustained by dedicated chaperones. RSC Advances, 11, pp. 32476-32493. (doi: 10.1039/D1RA04497D)

Dickson-Murray, E., Nedara, K., Modjtahedi, N., Tokatlidis, K. (2021) The Mia40/CHCHD4 oxidative folding system: Redox regulation and signaling in the mitochondrial intermembrane space. Antioxidants, 10, (doi: 10.3390/antiox10040592)

Butt, G. R., Qayyum, Z. A., Jones, M. A. (2020) Plant defence mechanisms are modulated by the circadian system. Biology, 9, (doi: 10.3390/biology9120454)

Alghamdi, F., Alshuweishi, Y., Salt, I. P. (2020) Regulation of nutrient uptake by AMP-activated protein kinase. Cellular Signalling, 76, (doi: 10.1016/j.cellsig.2020.109807)

Battle, M. W., Vegliani, F., Jones, M. A. (2020) Shades of green: untying the knots of green photoperception. Journal of Experimental Botany, 71, pp. 5764-5770. (doi: 10.1093/jxb/eraa312)

Chatrin, C., Gabrielsen, M., Buetow, L., Nakasone, M. A., Ahmed, S. F., Sumpton, D., Sibbet, G. J., Smith, B. O., Huang, D. T. (2020) Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases. Science Advances, 6, (doi: 10.1126/sciadv.abc0418)

Reinhardt, C., Arena, G., Nedara, K., Edwards, R., Brenner, C., Tokatlidis, K., Modjtahedi, N. (2020) AIF meets the CHCHD4/Mia40-dependent mitochondrial import pathway. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1866, (doi: 10.1016/j.bbadis.2020.165746)

Crecente Garcia, S., Neckebroeck, A., Clark, J. S., Smith, B. O., Thomson, A. R. (2020) β-turn mimics by chemical ligation. Organic Letters, 22, pp. 4424-4428. (doi: 10.1021/acs.orglett.0c01427)

Scialò, F., Sriram, A., Stefanatos, R., Spriggs, R. V., Loh, S. H.Y., Martins, L. M., Sanz, A. (2020) Mitochondrial complex I derived ROS regulate stress adaptation in Drosophila melanogaster. Redox Biology, 32, (doi: 10.1016/j.redox.2020.101450)

Edwards, R., Gerlich, S., Tokatlidis, K. (2020) The biogenesis of mitochondrial intermembrane space proteins. Biological Chemistry, 401, pp. 737-747. (doi: 10.1515/hsz-2020-0114)

Woodling, N. S., Aleyakpo, B., Dyson, M. C., Minkley, L. J., Rajasingam, A., Dobson, A. J., Leung, K. H. C., Pomposova, S., Fuentealba, M., Alic, N., Partridge, L. (2020) The neuronal receptor tyrosine kinase Alk is a target for longevity. Aging Cell, 19, (doi: 10.1111/acel.13137)

Crowe, J., Lumb, F. E., Doonan, J., Broussard, M., Tarafdar, A., Pineda, M. A., Landabaso, C., Mulvey, L., Hoskisson, P. A., Babayan, S. A., Selman, C., Harnett, W., Harnett, M. (2020) The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing. PLoS Pathogens, 16, (doi: 10.1371/journal.ppat.1008391)

Sáenz de Miera, C., Beymer, M., Routledge, K., Król, E., Selman, C., Hazlerigg, D. G., Simonneaux, V. (2020) Photoperiodic regulation in a wild-derived mouse strain. Journal of Experimental Biology, 223, (doi: 10.1242/jeb.217687)

Battle, M. W., Jones, M. A. (2020) Cryptochromes integrate green light signals into the circadian system. Plant, Cell and Environment, 43, pp. 16-27. (doi: 10.1111/pce.13643)

Dawson, N. J., Millet, C., Selman, C., Metcalfe, N. B. (2020) Measurement of mitochondrial respiration in permeabilized fish gills. Journal of Experimental Biology, 223, (doi: 10.1242/jeb.216762)

Wilkie, S. E., Mulvey, L., Sands, W., Marcu, D. E., Carter, R. N., Morton, N. M., Hine, C., Mitchell, J. R., Selman, C. (2020) Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice. GeroScience, 42, pp. 801-812. (doi: 10.1007/s11357-020-00168-2)

Lee, B. P., Mulvey, L., Barr, G., Garratt, J., Goodman, E., Selman, C., Harries, L. W. (2019) Dietary restriction in ILSXISS mice is associated with widespread changes in splicing regulatory factor expression levels. Experimental Gerontology, 128, (doi: 10.1016/j.exger.2019.110736)

Gubina, N., Naudi, A., Stefanatos, R., Jove, M., Scialo, F., Fernandez-Ayala, D. J., Rantapero, T., Yurkevych, I., Portero-Otin, M., Nykter, M., Lushchak, O., Navas, P., Pamplona, R., Sanz, A., Anderson, R. (2019) Essential physiological differences characterize short- and long-lived strains of Drosophila melanogaster. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 74, pp. 1835-1843. (doi: 10.1093/gerona/gly143)

Lumb, F. E., Crowe, J., Doonan, J., Suckling, C. J., Selman, C., Harnett, M. M., Harnett, W. (2019) Synthetic small molecule analogues of the immunomodulatory Acanthocheilonema viteae product ES-62 promote metabolic homeostasis during obesity in a mouse model. Molecular and Biochemical Parasitology, (doi: 10.1016/j.molbiopara.2019.111232)

Pulli, I., Löf, C., Blom, T., Asghar, M.Y., Lassila, T., Bäck, N., Lin, K.-L., Nyström, J.H., Kemppainen, K., Toivola, D.M., Dufour, E., Sanz, A., Cooper, H.M., Parys, J.B., Törnquist, K. (2019) Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells. Biochimica et Biophysica Acta: Molecular Cell Research, 1866, pp. 1475-1486. (doi: 10.1016/j.bbamcr.2019.06.006)

Shiels, P. G., Buchanan, S., Selman, C., Stenvinkel, P. (2019) Allostatic load and ageing; linking the microbiome and nutrition with age related health. Biochemical Society Transactions, 47, pp. 1165-1172. (doi: 10.1042/BST20190110)

Salin, K., Villasevil, E. M., Anderson, G. J., Lamarre, S. G., Melanson, C. A., McCarthy, I., Selman, C., Metcalfe, N. B. (2019) Differences in mitochondrial efficiency explain individual variation in growth performance. Proceedings of the Royal Society of London Series B: Biological Sciences, 286, (doi: 10.1098/rspb.2019.1466)

Ibáñez-Shimabukuro, M., Rey-Burusco, M. F., Gabrielsen, M., Franchini, G. R., Riboldi-Tunnicliffe, A., Roe, A. J., Griffiths, K., Cooper, A., Córsico, B., Kennedy, M. W., Smith, B. O. (2019) Structure and ligand binding of As-p18, an extracellular fatty acid binding protein from the eggs of a parasitic nematode. Bioscience Reports, 39, (doi: 10.1042/BSR20191292)

Dobson, A. J., Boulton-McDonald, R., Houchou, L., Svermova, T., Ren, Z., Subrini, J., Vazquez-Prada, M., Hoti, M., Rodriguez-Lopez, M., Ibrahim, R., Gregoriou, A., Gkantiragas, A., Bähler, J., Ezcurra, M., Alic, N. (2019) Longevity is determined by ETS transcription factors in multiple tissues and diverse species. PLoS Genetics, 15, (doi: 10.1371/journal.pgen.1008212)

Katwan, O. J., Alghamdi, F., Almabrouk, T. A., Mancini, S. J., Kennedy, S., Oakhill, J. S., Scott, J. W., Salt, I. P. (2019) AMP-activated protein kinase complexes containing the β2 regulatory subunit are upregulated during and contribute to adipogenesis. Biochemical Journal, 476, pp. 1725-1740. (doi: 10.1042/BCJ20180714)

Edwards, R., Tokatlidis, K. (2019) The yeast voltage-dependent anion channel Porin: more IMPORTant than just metabolite transport. Molecular Cell, 73, pp. 861-862. (doi: 10.1016/j.molcel.2019.02.028)

Jones, M. A. (2019) Retrograde signalling as an informant of circadian timing. New Phytologist, 221, pp. 1749-1753. (doi: 10.1111/nph.15525)

Knuhtsen, A., Whitmore, C., McWhinnie, F. S., McDougall, L., Whiting, R., Smith, B. O., Timperley, C. M., Green, A. C., Kinnear, K. I., Jamieson, A. G. (2019) α-conotoxin GI triazole-peptidomimetics: potent and stable blockers of a human acetylcholine receptor. Chemical Science, 10, pp. 1671-1676. (doi: 10.1039/C8SC04198A)

Jones, M. A., Morohashi, K., Grotewold, E., Harmer, S. L. (2019) Arabidopsis JMJD5/JMJ30 acts independently of LUX ARRHYTHMO within the plant circadian clock to enable temperature compensation. Frontiers in Plant Science, 10, (doi: 10.3389/fpls.2019.00057)

Rached, M.-T., Millership, S. J., Pedroni, S. M.A., Choudhury, A. I., Costa, A. S.H., Hardy, D. G., Glegola, J. A., Irvine, E. E., Selman, C., Woodberry, M. C., Yadav, V. K., Khadayate, S., Vidal-Puig, A., Virtue, S., Frezza, C., Withers, D. J. (2019) Deletion of myeloid IRS2 enhances adipose tissue sympathetic nerve function and limits obesity. Molecular Metabolism, 20, pp. 38-50. (doi: 10.1016/j.molmet.2018.11.010)

Petrie, J. R., Salt, I. P. (2019) Diabetes and vascular disease. Springer

Rezig, I. M., Bremner, S. K., Bhutta, M. S., Salt, I. P., Gould, G. W., McInerny, C. J. (2019) Genetic and cytological methods to study ESCRT cell cycle function in fission yeast. Humana Press

Simon, N. M.L., Litthauer, S., Jones, M. A., Dodd, A. N. (2019) Interactions between circadian rhythms, ROS and redox. Springer

Purohit, P. K., Edwards, R., Tokatlidis, K., Saini, N. (2019) MiR-195 regulates mitochondrial function by targeting mitofusin-2 in breast cancer cells. RNA Biology, 16, pp. 918-929. (doi: 10.1080/15476286.2019.1600999)

Wilkinson, M. J.A., Selman, C., McLaughlin, L., Horan, L., Hamilton, L., Gilbert, C., Chadwick, C., Flynn, J. N. (2019) Progressing the care, husbandry and management of ageing mice used in scientific studies. Laboratory Animals, 54, pp. 225-238. (doi: 10.1177/0023677219865291)

Strembitska, A., Mancini, S. J., Gamwell, J. M., Palmer, T. M., Baillie, G. S., Salt, I. P. (2018) A769662 inhibits insulin-stimulated Akt activation in human macrovascular endothelial cells independent of AMP-activated protein kinase. International Journal of Molecular Sciences, 19, (doi: 10.3390/ijms19123886)

Selman, C., Swindell, W. R. (2018) Putting a strain on diversity. EMBO Journal, 37, (doi: 10.15252/embj.2018100862)

Thompson, K. et al. (2018) OXA 1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect. EMBO Molecular Medicine, 10, (doi: 10.15252/emmm.201809060)

Jones, M. A. (2018) Using light to improve commercial value. Horticulture Research, 5, (doi: 10.1038/s41438-018-0049-7)

Salin, K., Villasevil, E. M., Anderson, G. J., Auer, S. K., Selman, C., Hartley, R. C., Mullen, W., Chinopoulos, C., Metcalfe, N. B. (2018) Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost. Functional Ecology, 32, pp. 2149-2157. (doi: 10.1111/1365-2435.13125)

Panagiotou, N., Neytchev, O., Selman, C., Shiels, P. G. (2018) Extracellular vesicles, ageing, and therapeutic interventions. Cells, 7, (doi: 10.3390/cells7080110)

Pacios-Palma, I., Moreno, S., Selman, C., Rouco, C. (2018) Oxidative stress in wild European rabbits naturally infected with myxoma virus and rabbit haemorrhagic disease virus. European Journal of Wildlife Research, 64, (doi: 10.1007/s10344-018-1203-0)

Salin, K., Villasevil, E. M., Anderson, G. J., Selman, C., Chinopoulos, C., Metcalfe, N. B. (2018) The RCR and ATP/O indices can give contradictory messages about mitochondrial efficiency. Integrative and Comparative Biology, 58, pp. 486-494. (doi: 10.1093/icb/icy085)

Tokatlidis, K. (2018) Shaping the import system of mitochondria. eLife, 7, (doi: 10.7554/elife.38209)

Cardenas-Rodriguez, M., Chatzi, A., Tokatlidis, K. (2018) Iron–sulfur clusters: from metals through mitochondria biogenesis to disease. Journal of Biological Inorganic Chemistry, 23, pp. 509-520. (doi: 10.1007/s00775-018-1548-6)

Page, M. M., Schuster, E. F., Mudaliar, M., Herzyk, P., Withers, D. J., Selman, C. (2018) Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice. Aging, 10, pp. 1027-1052. (doi: 10.18632/aging.101446)

Dobson, A. J., He, X., Blanc, E., Bolukbasi, E., Feseha, Y., Yang, M., Piper, M. D.W. (2018) Tissue-specific transcriptome profiling of Drosophila reveals roles for GATA transcription factors in longevity by dietary restriction. npj Aging and Mechanisms of Disease, 4, (doi: 10.1038/s41514-018-0024-4)

Egea, J. et al. (2018) Corrigendum to “European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” [Redox Biol. 13 (2017) 94–162] Redox Biology, 14, pp. 694-696. (doi: 10.1016/j.redox.2017.10.001)

Mancini, S. J., Boyd, D., Katwan, O. J., Strembitska, A., Almabrouk, T. A., Kennedy, S., Palmer, T. M., Salt, I. P. (2018) Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms. Scientific Reports, 8, (doi: 10.1038/s41598-018-23420-4)

Stefanatos, R., Sanz, A. (2018) The role of mitochondrial ROS in the aging brain. FEBS Letters, 592, pp. 743-758. (doi: 10.1002/1873-3468.12902)

Sannino, D. R., Dobson, A. J., Edwards, K., Angert, E. R., Buchon, N. (2018) The Drosophila melanogaster gut microbiota provisions thiamine to its host. mBio, 9, (doi: 10.1128/mBio.00155-18)

Litthauer, S., Chan, K. X., Jones, M. (2018) 3'-phosphoadenosine 5'-phosphate accumulation delays the circadian system. Plant Physiology, 176, pp. 3120-3135. (doi: 10.1104/pp.17.01611)

Almabrouk, T. A.M., White, A. D., Ugusman, A. B., Skiba, D. S., Katwan, O. J., Alganga, H., Guzik, T. J., Touyz, R. M., Salt, I. P., Kennedy, S. (2018) High fat diet attenuates the anticontractile activity of aortic PVAT via a mechanism involving AMPK and reduced adiponectin secretion. Frontiers in Physiology, 9, (doi: 10.3389/fphys.2018.00051)

Speirs, C., Williams, J. J.L., Riches, K., Salt, I. P., Palmer, T. M. (2018) Linking energy sensing to suppression of JAK-STAT signalling: a potential route for repurposing AMPK activators? Pharmacological Research, 128, pp. 88-100. (doi: 10.1016/j.phrs.2017.10.001)

Carroll, B., Otten, E. G., Manni, D., Stefanatos, R., Menzies, F. M., Smith, G. R., Jurk, D., Kenneth, N., Wilkinson, S., Passos, J. F., Attems, J., Veal, E. A., Teyssou, E., Seilhean, D., Millecamps, S., Eskelinen, E.-L., Bronowska, A. K., Rubinsztein, D. C., Sanz, A., Korolchuk, V. I. (2018) Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis. Nature Communications, 9, (doi: 10.1038/s41467-017-02746-z)

Babayan, S. A., Sinclair, A., Duprez, J. S., Selman, C. (2018) Chronic helminth infection burden differentially affects haematopoietic cell development while ageing selectively impairs adaptive responses to infection. Scientific Reports, 8, (doi: 10.1038/s41598-018-22083-5)

Mancini, S. J., Salt, I. P. (2018) Investigating the role of AMPK in inflammation. Humana Press

Litthauer, S., Jones, M. A. (2018) SAL1-PAP retrograde signalling extends circadian period by reproducing the loss of exoribonuclease (XRN) activity. Plant Signaling and Behavior, 13,

Filer, D., Thompson, M. A., Takhaveev, V., Dobson, A. J., Kotronaki, I., Green, J. W.M., Heinemann, M., Tullet, J. M.A., Alic, N. (2017) RNA polymerase III limits longevity downstream of TORC1. Nature, 552, pp. 263-267. (doi: 10.1038/nature25007)

Cooper, A., Vance, S. J., Smith, B. O., Kennedy, M. W. (2017) Frog foams and natural protein surfactants. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 534, pp. 120-129. (doi: 10.1016/j.colsurfa.2017.01.049)

Jones, M. A. (2017) Interplay of circadian rhythms and light in the regulation of photosynthesis-derived metabolism. Springer

Mulvey, L., Sands, W. A., Salin, K., Carr, A. E., Selman, C. (2017) Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice. Molecular and Cellular Endocrinology, 455, pp. 41-53. (doi: 10.1016/j.mce.2016.09.001)

Gabrielsen, M., Buetow, L., Nakasone, M. A., Ahmed, S. F., Sibbet, G. J., Smith, B. O., Zhang, W., Sidhu, S. S., Huang, D. T. (2017) A general strategy for discovery of inhibitors and activators of RING and U-box E3 ligases with ubiquitin variants. Molecular Cell, 68, pp. 456-470.e10. (doi: 10.1016/j.molcel.2017.09.027)

Sands, W. A., Page, M. M., Selman, C. (2017) Proteostasis and ageing: insights from long-lived mutant mice. Journal of Physiology, 595, pp. 6383-6390. (doi: 10.1113/JP274334)

Almabrouk, T. A. M., Ugusman, A. B., Katwan, O. J., Salt, I. P., Kennedy, S. (2017) Deletion of AMPKα1 attenuates the anticontractile effect of perivascular adipose tissue (PVAT) and reduces adiponectin release. British Journal of Pharmacology, 174, pp. 3398-3410. (doi: 10.1111/bph.13633)

Egea, J. et al. (2017) European contribution to the study of ROS: a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) Redox Biology, 13, pp. 94-162. (doi: 10.1016/j.redox.2017.05.007)

Kennedy, S., Salt, I. P. (2017) Molecular mechanisms regulating perivascular adipose tissue - potential pharmacological targets? British Journal of Pharmacology, 174, pp. 3385-3387. (doi: 10.1111/bph.13969)

Magennis, S., Toulmin, A., Baltierra-Jasso, L. E., Morten, M. J., Sabir, T., McGlynn, P., Schröder, G. F., Smith, B. O., Magennis, S. W. (2017) Conformational heterogeneity in a fully-complementary DNA three-way junction with a GC-rich branchpoint. Biochemistry, 56, pp. 4985-4991. (doi: 10.1021/acs.biochem.7b00677)

Cardenas-Rodriguez, M., Tokatlidis, K. (2017) Cytosolic redox components regulate protein homeostasis via additional localisation in the mitochondrial intermembrane space. FEBS Letters, 591, pp. 2661-2670. (doi: 10.1002/1873-3468.12766)

Spies, M., Smith, B. O. (2017) Protein-nucleic acids interactions: new ways of connecting structure, dynamics and function. Biophysical Reviews, 9, pp. 289-291. (doi: 10.1007/s12551-017-0284-4)

MacPherson, L., Tokatlidis, K. (2017) Protein trafficking in the mitochondrial intermembrane space: mechanisms and links to human disease. Biochemical Journal, 474, pp. 2533-2545. (doi: 10.1042/BCJ20160627)

Scialò, F., Fernández-Ayala, D. J., Sanz, A. (2017) Role of mitochondrial reverse electron transport in ROS signaling: potential roles in health and disease. Frontiers in Physiology, 8, (doi: 10.3389/fphys.2017.00428)

Hine, C. et al. (2017) Hypothalamic-pituitary axis regulates hydrogen sulfide production. Cell Metabolism, 25, pp. 1320-1333.e5. (doi: 10.1016/j.cmet.2017.05.003)

Salt, I. P., Hardie, G. (2017) AMP-activated protein kinase: an ubiquitous signalling pathway with key roles in the cardiovascular system. Circulation Research, 120, pp. 1825-1841. (doi: 10.1161/CIRCRESAHA.117.309633)

Brandani, G. B., Vance, S. J., Schor, M., Cooper, A., Kennedy, M. W., Smith, B. O., MacPhee, C. E., Cheung, D. L. (2017) Adsorption of the natural protein surfactant Rsn-2 onto liquid interfaces. Physical Chemistry Chemical Physics, 19, pp. 8584-8594. (doi: 10.1039/C6CP07261E)

Parnell, E., McElroy, S. P., Wiejak, J., Baillie, G. L., Porter, A., Adams, D. R., Rehmann, H., Smith, B. O., Yarwood, S. J. (2017) Identification of a novel, small molecule partial agonist for the cyclic AMP sensor, EPAC1. Scientific Reports, 7, (doi: 10.1038/s41598-017-00455-7)

Kritsiligkou, P., Chatzi, A., Charalampous, G., Mironov, A., Grant, C. M., Tokatlidis, K. (2017) Unconventional targeting of a thiol peroxidase to the mitochondrial intermembrane space facilitates oxidative protein folding. Cell Reports, 18, pp. 2729-2741. (doi: 10.1016/j.celrep.2017.02.053)

Chen, S.C., Brooks, R., Houskeeper, J., Bremner, S.K., Dunlop, J., Viollet, B., Logan, P.J., Salt, I.P., Ahmed, S.F., Yarwood, S.J. (2017) Corrigendum to "Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms" [Mol. Cell. Endocrinol. 440 15 January 2017 57-68] Molecular and Cellular Endocrinology, 443, pp. 176. (doi: 10.1016/j.mce.2017.01.049)

Dobson, A. J., Chaston, J. M., Douglas, A. E. (2017) Erratum to: The Drosophila transcriptional network is structured by microbiota. BMC Genomics, 18, (doi: 10.1186/s12864-017-3508-x)

Selman, C., Withers, D. J. (2017) Physiology: an atypical switch for metabolism and ageing. Nature, 542, pp. 299-300. (doi: 10.1038/nature21500)

Mancini, S. J., White, A. D., Bijland, S., Rutherford, C., Graham, D., Richter, E. A., Viollet, B., Touyz, R. M., Palmer, T. M., Salt, I. P. (2017) Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptorassociated kinase-4 phosphorylation. Molecular and Cellular Endocrinology, 440, pp. 44-56. (doi: 10.1016/j.mce.2016.11.010)

Chen, S. C., Brooks, R., Houskeeper, J., Bremner, S. K., Dunlop, J., Viollet, B., Logan, P. J., Salt, I. P., Ahmed, S. F., Yarwood, S. J. (2017) Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms. Molecular and Cellular Endocrinology, 440, pp. 57-68. (doi: 10.1016/j.mce.2016.11.011)

Dobson, A. J., Ezcurra, M., Flanagan, C. E., Summerfield, A. C., Piper, M. D.W., Gems, D., Alic, N. (2017) Nutritional programming of lifespan by FOXO inhibition on sugar-rich diets. Cell Reports, 18, pp. 299-306. (doi: 10.1016/j.celrep.2016.12.029)

Manganas, P., MacPherson, L., Tokatlidis, K. (2017) Oxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space. Cell and Tissue Research, 367, pp. 43-57. (doi: 10.1007/s00441-016-2488-5)

Malpas, K. R., Jones, M. A. (2016) Natural variation of circadian rhythms in Kalanchoe species. Haseltonia, 2016, pp. 35-42. (doi: 10.2985/026.022.0107)

Figueira, I., Fernandes, A., Mladenovic, A., Lopez-Contreras, A., Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, L. J., Xapelli, S., Ellam, T., Bellantuono, I. (2016) Interventions for age-related diseases: Shifting the paradigm. Mechanisms of Ageing and Development, 160, pp. 69-92. (doi: 10.1016/j.mad.2016.09.009)

Docherty, C. K., Salt, I. P., Mercer, J. R. (2016) Lin28A induces energetic switching to glycolytic metabolism in human embryonic kidney cells. Stem Cell Research and Therapy, 7, (doi: 10.1186/s13287-016-0323-2)

Panagiotou, N., Davies, R. W., Selman, C., Shiels, P. G. (2016) Microvesicles as vehicles for tissue regeneration: Changing of the guards. Current Pathobiology Reports, 4, pp. 181-187. (doi: 10.1007/s40139-016-0115-5)

Heathcote, H. R., Mancini, S. J., Strembitska, A., Jamal, K., Reihill, J. A., Palmer, T. M., Gould, G. W., Salt, I. P. (2016) Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487. Biochemical Journal, 473, pp. 4681-4697. (doi: 10.1042/BCJ20160211)

Dobson, A. J., Chaston, J. M., Douglas, A. E. (2016) The Drosophila transcriptional network is structured by microbiota. BMC Genomics, 17, (doi: 10.1186/s12864-016-3307-9)

Rutherford, C., Speirs, C., Williams, J. J.L., Ewart, M.-A., Mancini, S. J., Hawley, S. A., Delles, C., Viollet, B., Costa-Pereira, A. P., Baillie, G. S., Salt, I. P., Palmer, T. M. (2016) Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. Science Signaling, 9, (doi: 10.1126/scisignal.aaf8566)

Nuebel, E., Manganas, P., Tokatlidis, K. (2016) Orphan proteins of unknown function in the mitochondrial intermembrane space proteome: new pathways and metabolic cross-talk. Biochimica et Biophysica Acta: Molecular Cell Research, 1863, pp. 2613-2623. (doi: 10.1016/j.bbamcr.2016.07.004)

Salin, K., Auer, S. K., Rudolf, A. M., Anderson, G. J., Selman, C., Metcalfe, N. B. (2016) Variation in metabolic rate among individuals is related to tissue-specific differences in mitochondrial leak respiration. Physiological and Biochemical Zoology, 89, pp. 511-523. (doi: 10.1086/688769)

Grinter, R., Josts, I., Mosbahi, K., Roszak, A. W., Cogdell, R. J., Bonvin, A. M.J.J., Milner, J. J., Kelly, S. M., Byron, O., Smith, B. O., Walker, D. (2016) Structure of the bacterial plant-ferredoxin receptor FusA. Nature Communications, 7, (doi: 10.1038/ncomms13308)

Salin, K., Villasevil, E. M., Auer, S. K., Anderson, G. J., Selman, C., Metcalfe, N. B., Chinopoulos, C. (2016) Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios. Physiological Reports, 4, (doi: 10.14814/phy2.13007)

Christensen, L. L., Selman, C., Blount, J. D., Pilkington, J. G., Watt, K. A., Pemberton, J. M., Reid, J., Nussey, D. H. (2016) Marker-dependent associations among oxidative stress, growth and survival during early life in a wild mammal. Proceedings of the Royal Society of London Series B: Biological Sciences, 283, (doi: 10.1098/rspb.2016.1407)

Heilmann, M., Velanis, C. N., Cloix, C., Smith, B. O., Christie, J. M., Jenkins, G. I. (2016) Dimer/monomer status and in vivo function of salt-bridge mutants of the plant UV-B photoreceptor UVR8. Plant Journal, 88, pp. 71-81. (doi: 10.1111/tpj.13260)

Hawley, S. A., Ford, R. J., Smith, B. K., Gowans, G. J., Mancini, S., Pitt, R. D., Day, E. A., Salt, I. P., Steinberg, G. R., Hardie, D. G. (2016) The Na+ glucose co-transporter inhibitor canagliflozin activates AMP-activated protein kinase by inhibiting mitochondrial function and increasing cellular AMP levels. Diabetes, 65, pp. 2784-2794. (doi: 10.2337/db16-0058)

Antoniewski, C., Scialo, F., Sriram, A., Stefanatos, R., Sanz, A. (2016) Practical recommendations for the use of the GeneSwitch Gal4 system to knock-down genes in Drosophila melanogaster. PLoS ONE, 11, (doi: 10.1371/journal.pone.0161817)

Morris, R. J., Brandani, G. B., Desai, V., Smith, B. O., Schor, M., MacPhee, C. E. (2016) The conformation of interfacially adsorbed Ranaspumin-2 Is an arrested state on the unfolding pathway. Biophysical Journal, 111, pp. 732-742. (doi: 10.1016/j.bpj.2016.06.006)

Dean, A., Nilsen, M., Loughlin, L., Salt, I. P., MacLean, M. R. (2016) Metformin reverses development of pulmonary hypertension via aromatase inhibition. Hypertension, 68, pp. 446-454. (doi: 10.1161/HYPERTENSIONAHA.116.07353)

Sanz, A. (2016) Mitochondrial reactive oxygen species: Do they extend or shorten animal lifespan? Biochimica et Biophysica Acta: Bioenergetics, 1857, pp. 1116-1126. (doi: 10.1016/j.bbabio.2016.03.018)

Kalef-Ezra, E., Kotzamani, D., Zaganas, I., Katrakili, N., Plaitakis, A., Tokatlidis, K. (2016) Import of a major mitochondrial enzyme depends on synergy between two distinct helices of its presequence. Biochemical Journal, 473, pp. 2813-2829. (doi: 10.1042/BCJ20160535)

Vance, S. J., Desai, V., Smith, B. O., Kennedy, M. W., Cooper, A. (2016) Aqueous solubilization of C60 fullerene by natural protein surfactants, latherin and ranaspumin-2. Biophysical Chemistry, 214-15, pp. 27-32. (doi: 10.1016/j.bpc.2016.05.003)

Johnston, P. R., Dobson, A. J., Rolff, J. (2016) Genomic signatures of experimental adaptation to antimicrobial peptides in Staphylococcus aureus. G3: Genes, Genomes, Genetics, 6, pp. 1535-1539. (doi: 10.1534/g3.115.023622)

Chatzi, A., Manganas, P., Tokatlidis, K. (2016) Oxidative folding in the mitochondrial intermembrane space: a regulated process important for cell physiology and disease. Biochimica et Biophysica Acta: Molecular Cell Research, 1863, pp. 1298-1306. (doi: 10.1016/j.bbamcr.2016.03.023)

Makarova, O., Rodriguez-Rojas, A., Eravci, M., Weise, C., Dobson, A., Johnston, P., Rolff, J. (2016) Antimicrobial defence and persistent infection in insects revisited. Philosophical Transactions of the Royal Society B: Biological Sciences, 371, (doi: 10.1098/rstb.2015.0296)

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