2024
Articles
Adamson, W. E. et al. (2024) Phenome-wide analysis reveals epistatic associations between APOL1 variants and chronic kidney disease and multiple other disorders. EBioMedicine, 101, 105000. (doi: 10.1016/j.ebiom.2024.105000) (PMID:38360481) (PMCID:PMC10944146)
Ayuso-García, P. et al. (2024) Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination. Science Advances, 10(15), eadm7600. (doi: 10.1126/sciadv.adm7600) (PMID:38608019) (PMCID:PMC11014456)
Baena, G. , Xia, L. , Waghmare, S. , Yu, Z., Guo, Y., Blatt, M. R. , Zhang, B. and Karnik, R. (2024) Arabidopsis SNARE SYP132 impacts on PIP2;1 trafficking and function in salinity stress. Plant Journal, 118(4), pp. 1036-1053. (doi: 10.1111/tpj.16649) (PMID:38289468)
Barcelona-Estaje, E., Oliva, M. A.G., Cunniffe, F., Rodrigo-Navarro, A. , Genever, P., Dalby, M. J. , Roca-Cusachs, P., Cantini, M. and Salmeron-Sanchez, M. (2024) N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity. Nature Communications, 15, 8824. (doi: 10.1038/s41467-024-53107-6) (PMID:39394209)
Battle, M. W., Ewing, S. F., Dickson, C., Obaje, J., Edgeworth, K. N., Bindbeutel, R., Antoniou Kourounioti, R. L. , Nusinow, D. A., and Jones, M. A. (2024) Manipulation of photosensory and circadian signalling restricts phenotypic plasticity in response to changing environmental conditions in Arabidopsis. Molecular Plant, 17(9), pp. 1458-1471. (doi: 10.1016/j.molp.2024.07.007) (PMID:39014898)
Blanco-Melo, D., Campbell, M. A., Zhu, H., Dennis, T. P., Modha, S. , Lytras, S., Hughes, J. , Gatseva, A. and Gifford, R. J. (2024) A novel approach to exploring the dark genome and its application to mapping of the vertebrate virus fossil record. Genome Biology, 25(1), 120. (doi: 10.1186/s13059-024-03258-y) (PMID:38741126) (PMCID:PMC11089739)
Blatt, M. R. (2024) A charged existence: a century of transmembrane ion transport in plants. Plant Physiology, (doi: 10.1093/plphys/kiad630) (PMID:38163639) (Early Online Publication)
Borland, G., Wilkie, S. E., Thomson, J., Wang, Z., Tullett, J. M.A., Alic, N. and Selman, C. (2024) Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan. Aging Cell, 23(5), e14141. (doi: 10.1111/acel.14141) (PMID:38465473) (PMCID:PMC11113255)
Brettell, S. B. et al. (2024) Targeting PfCLK3 with covalent inhibitors: a novel strategy for malaria treatment. Journal of Medicinal Chemistry, (doi: 10.1021/acs.jmedchem.4c01300) (PMID:39441986) (Early Online Publication)
Busch, C., Nyamondo, K. and Wheadon, H. (2024) Complexities of modelling the bone marrow microenvironment to facilitate haematopoietic research. Experimental Hematology, 135, 104233. (doi: 10.1016/j.exphem.2024.104233) (PMID:38740324)
Busch, F. A. et al. (2024) A guide to photosynthetic gas exchange measurements: fundamental principles, best practice and potential pitfalls. Plant, Cell and Environment, (doi: 10.1111/pce.14815) (PMID:38321805) (Early Online Publication)
Castejón-Vega, B. , Kyriakidis, N. C., Alcócer-Gómez, E., Giampieri, F., González-Paramás, A. M., Cordero, M. D. and Alvarez-Suarez, J. M. (2024) Modulatory effect of Andean blackberry polyphenols on genes related to antioxidant and inflammatory responses, the NLRP3 inflammasome, and autophagy. Journal of Berry Research, 14(1), p. 41. (doi: 10.3233/jbr-230058)
Chapple, K. J. et al. (2024) A myelinic channel system for motor-driven organelle transport. bioRxiv, (doi: 10.1101/2024.06.02.591488)
Cogdell, R. (2024) Reviewers in 2023. Journal of The Royal Society Interface, 21(212), 20240126. (doi: 10.1098/rsif.2024.0126) (PMCID:PMC10965321)
Cuahtecontzi Delint, R. et al. (2024) Nanotopography influences host-pathogen quorum sensing and facilitates selection of bioactive metabolites in mesenchymal stromal cells and pseudomonas aeruginosa co-cultures. ACS Applied Materials and Interfaces, (doi: 10.1021/acsami.4c09291) (PMID:39113638) (Early Online Publication)
Cuahtecontzi Delint, R., Jaffery, H., Ishak, M. I., Nobbs, A. H., Su, B. and Dalby, M. J. (2024) Mechanotransducive surfaces for enhanced cell osteogenesis, a review. Biomaterials Advances, 160, 213861. (doi: 10.1016/j.bioadv.2024.213861) (PMID:38663159)
Dalby, M. J. , Pekovic‐Vaughan, V., Shanley, D. P., Swift, J., White, L. J. and Canty‐Laird, E. G. (2024) Strengths and opportunities in research into extracellular matrix ageing: a consultation with the ECMage research community. BioEssays, 46(5), 2300223. (doi: 10.1002/bies.202300223) (PMID:38522027)
Dearlove, E. L., Chatrin, C., Buetow, L., Ahmed, S. F. , Schmidt, T., Bushell, M. , Smith, B. O. and Huang, D. T. (2024) DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids. eLife, 13, RP98070. (doi: 10.7554/elife.98070) (PMID:39377462)
Dhawan, U. , Williams, J. A., Windmill, J. F.C., Childs, P., Gonzalez-Garcia, C., Dalby, M. J. and Salmeron-Sanchez, M. (2024) Engineered surfaces that promote capture of latent proteins to facilitate integrin-mediated mechanical activation of growth factors. Advanced Materials, 36(23), 2310789. (doi: 10.1002/adma.202310789) (PMID:38253339)
Doherty-Boyd, W. S., Tsimbouri, M. P. , Donnelly, H. and Dalby, M. J. (2024) Building bones for blood and beyond: the growing field of bone marrow niche model development. Experimental Hematology, 135, 104232. (doi: 10.1016/j.exphem.2024.104232) (PMID:38729553)
Donnelly, H. et al. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, 5791. (doi: 10.1038/s41467-024-50054-0)
Guiotto, M., Clayton, A., Morgan, R., Raffoul, W., Hart, A., Riehle, M. O. and Summa, P. (2024) Biogelx-IKVAV is an innovative HPL-ADSC delivery strategy to improve peripheral nerve repair. Tissue Engineering Part A, 30(21-22), pp. 681-692. (doi: 10.1089/ten.TEA.2023.0307) (PMID:38482791)
Harnett, M. M. , Doonan, J. , Tarafdar, A., Pineda, M. , Duncombe-Moore, J., Buitrago, G., Pan, P., Hoskisson, P., Selman, C. and Harnett, W. (2024) The parasitic worm product ES-62 protects against collagen-induced arthritis by resetting the gut-bone marrow axis in a microbiome-dependent manner. Frontiers in Tropical Diseases, 4, 1334705. (doi: 10.3389/fitd.2023.1334705)
Hermantara, R., Richmond, L., Taqi, A. F., Chilaka, S., Jeantet, V., Guerrini, I., West, K. and West, A. (2024) Improving CRISPR-Cas9 directed faithful transgene integration outcomes by reducing unwanted random DNA integration. Journal of Biomedical Science, 31(1), 32. (doi: 10.1186/s12929-024-01020-x) (PMID:38532479) (PMCID:PMC10964699)
Holt, C. and Carver, J.A. (2024) Invited review: Modeling milk stability. Journal of Dairy Science, 107(8), pp. 5259-5279. (doi: 10.3168/jds.2024-24779) (PMID:38522835)
Ibrahim, R., Dobson, A. and Bahilo Martinez, M. (2024) Rapamycin’s lifespan effect is modulated by mito-nuclear epistasis in Drosophila. Aging Cell, (doi: 10.1111/acel.14328) (PMID:39225061) (Early Online Publication)
Ishak, M. I., Cuahtecontzi Delint, R., Liu, X., Xu, W., Tsimbouri, P. M. , Nobbs, A. H., Dalby, M. J. and Su, B. (2024) Nanotextured titanium inhibits bacterial activity and supports cell growth on 2D and 3D substrate: a co-culture study. Biomaterials Advances, 158, 213766. (doi: 10.1016/j.bioadv.2024.213766) (PMID:38232578)
Jenkinson, M. R.J., Meek, D. R.M., Tate, R., Brady, A., MacMillan, S., Grant, H. and Currie, S. (2024) Cardiac function may be compromised in patients with elevated blood cobalt levels secondary to metal-on-metal hip implants. Bone and Joint Journal, 106-B(3A), pp. 51-58. (doi: 10.1302/0301-620X.106B3.BJJ-2023-0814.R1) (PMID:38423080)
Keating, C. , Kilbride, E., Stalham, M. A., Nellist, C., Milner, J. , Humphris, S., Toth, I. , Mable, B. K. and Ijaz, U. Z. (2024) Balancing the scales: assessing the impact of irrigation and pathogen burden on potato blackleg disease and soil microbial communities. Microbiome, 12, 210. (doi: 10.1186/s40168-024-01918-6)
Kim, K.-H. et al. (2024) Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington’s disease. Proceedings of the National Academy of Sciences, 121(16), e232292412. (doi: 10.1073/pnas.2322924121) (PMID:38607933)
Koszela, J., Rintala-Dempsey, A., Salzano, G. , Pimenta, V., Kamarainen, O., Gabrielsen, M. , Parui, A. L. , Shaw, G. S. and Walden, H. (2024) A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1. bioRxiv, (doi: 10.1101/2024.06.03.597144)
Kulkarni, J. et al. (2024) Early-responsive molecular signatures associated with halophytic adaptation in Sesuvium portulacastrum (L.). Plant, Cell and Environment, 47(3), pp. 961-975. (doi: 10.1111/pce.14767) (PMID:38044749)
Leader, D. P. (2024) E. James Milner-White (1945–2023). Proteins: Structure Function and Bioinformatics, 92(6), pp. 691-692. (doi: 10.1002/prot.26664) (PMID:38197126)
Leader, D. P. and Coggins, J. R. (2024) E. James Milner-White, 1945–2023. Biochemist, 46(1), pp. 34-35. (doi: 10.1042/bio_2024_108)
Leader, D. P. , Naseem, M. T. and Halberg, K. V. (2024) BeetleAtlas: an ontogenetic and tissue-specific transcriptomic atlas of the red flour beetle Tribolium castaneum. Journal of Molecular Biology, 436(17), 168520. (doi: 10.1016/j.jmb.2024.168520)
Lee, J. Y., Gala, D. S., Kiourlappou, M., Olivares-Abril, J., Joha, J., Titlow, J. S., Teodoro, R. O. and Davis, I. (2024) Murine glial protrusion transcripts predict localized Drosophila glial mRNAs involved in plasticity. Journal of Cell Biology, 223(10), e202306152. (doi: 10.1083/jcb.202306152) (PMID:39037431) (PMCID:PMC11262410)
Lee, J. Y., Huang, N., Samuels, T. J. and Davis, I. (2024) Imp and Syp in vivo temporal RNA interactomes uncover networks of temporal regulators of Drosophila brain development. bioRxiv, (doi: 10.1101/2024.06.30.600407)
Leighton, D. J. et al. (2024) Genotypes and phenotypes of motor neuron disease: an update of the genetic landscape in Scotland. Journal of Neurology, (doi: 10.1007/s00415-024-12450-w) (PMID:38852112) (Early Online Publication)
Liu, W. et al. (2024) Phosphorylation of Arabidopsis UVR8 photoreceptor modulates protein interactions and responses to UV-B radiation. Nature Communications, 15(1), 1221. (doi: 10.1038/s41467-024-45575-7) (PMID:38336824) (PMCID:PMC10858049)
Liu, W. and Jenkins, G. (2024) Recent advances in UV-B signalling: Interaction of proteins with the UVR8 photoreceptor. Journal of Experimental Botany, (doi: 10.1093/jxb/erae132) (Early Online Publication)
López-Laguna, H. et al. (2024) Hybrid micro-/nanoprotein platform provides endocrine-like and extracellular matrix-like cell delivery of growth factors. ACS Applied Materials and Interfaces, 16(26), pp. 32930-32944. (doi: 10.1021/acsami.4c01210) (PMID:38888932) (PMCID:PMC11231985)
MacDonald, A. I., Baksh, A., Holland, A., Shin, H., Rice, P. A., Stark, W. M. and Olorunniji, F. J. (2024) Variable orthogonality of serine integrase interactions within the ϕC31 family. Scientific Reports, 14(1), 26280. (doi: 10.1038/s41598-024-77570-9) (PMID:39487291)
Mangione, F., Titlow, J., Maclachlan, C., Gho, M., Davis, I. , Collinson, L. and Tapon, N. (2024) Author Correction: Co-option of epidermal cells enables touch sensing. Nature Cell Biology, 26(1), p. 170. (doi: 10.1038/s41556-023-01326-2) (PMID:38057364) (PMCID:PMC10791575)
Marsango, S. and Milligan, G. (2024) Regulation of the pro-inflammatory G protein-coupled receptor GPR84. British Journal of Pharmacology, 181(10), pp. 1500-1508. (doi: 10.1111/bph.16098) (PMID:37085331)
McNeilly, S. et al. (2024) Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage. EBioMedicine, 107, 105315. (doi: 10.1016/j.ebiom.2024.105315) (PMID:39216230)
Milligan, G. (2024) Editorial for GPR84 Pharmacology. British Journal of Pharmacology, 181(10), pp. 1497-1499. (doi: 10.1111/bph.16340)
Minnis, H. et al. (2024) The bio-exposome: intracellular processes, stress physiology and the environment. Nature Mental Health, 2(2), pp. 132-140. (doi: 10.1038/s44220-023-00180-3)
Myburgh, E., Geoghegan, V., Alves-Ferreira, E. V.C., Nievas, Y. R., Grewal, J. S., Brown, E., McLuskey, K. and Mottram, J. C. (2024) TORC1 is an essential regulator of nutrient-controlled proliferation and differentiation in Leishmania. EMBO Reports, 25(3), pp. 1075-1105. (doi: 10.1038/s44319-024-00084-y) (PMID:38396206) (PMCID:PMC10933368)
Nguyen, H. T. M., van der Westhuizen, E. T., Langmead, C. J., Tobin, A. B. , Sexton, P. M., Christopoulos, A. and Valant, C. (2024) Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits. British Journal of Pharmacology, 181(14), pp. 2114-2142. (doi: 10.1111/bph.15982) (PMID:36355830)
Nguyen, T.-H. and Blatt, M. R. (2024) Surrounded by luxury: the necessities of subsidiary cells. Plant, Cell and Environment, (doi: 10.1111/pce.14872) (PMID:38436128) (Early Online Publication)
Nyamondo, K. and Wheadon, H. (2024) Microenvironment alterations through time leading to myeloid malignancies. British Journal of Pharmacology, 181(2), pp. 283-294. (doi: 10.1111/bph.15924) (PMID:35844165)
Olivares-Abril, J., Joha, J., Lee, J. Y. and Davis, I. (2024) Optimization of hybridization chain reaction for imaging single RNA molecules in Drosophila larvae. Fly, 18(1), 2409968. (doi: 10.1080/19336934.2024.2409968) (PMID:39351922)
Pal, S., Nare, Z., Rao, V. A., Smith, B. O. , Morrison, I., Fitzgerald, E. A., Scott, A., Bingham, M. J. and Pesnot, T. (2024) Accelerating BRPF1b hit identification with BioPhysical and Active Learning Screening (BioPALS). ChemMedChem, 19(6), e202300590. (doi: 10.1002/cmdc.202300590) (PMID:38372199)
Pan, P., Wang, Y., Nyirenda, M. H., Saiyed, Z., Karimian Azari, E., Sunderman, A., Milling, S. , Harnett, M. M. and Pineda, M. (2024) Undenatured type II collagen protects against collagen-induced arthritis by restoring gut-joint homeostasis and immunity. Communications Biology, 7, 804. (doi: 10.1038/s42003-024-06476-z) (PMID:38961129)
Piñera-Avellaneda, D., Buxadera-Palomero, J., Cuahtecontzi Delint, R., Dalby, M. J. , Burgess, K. V., Ginebra, M.-P., Rupérez, E. and Manero, J. M. (2024) Gallium and silver-doped titanium surfaces provide enhanced osteogenesis, reduce bone resorption and prevent bacterial infection in co-culture. Acta Biomaterialia, 180, pp. 154-170. (doi: 10.1016/j.actbio.2024.04.019) (PMID:38621600)
Raynes, J. K., Mata, J., Wilde, K. L., Carver, J. A., Kelly, S. M. and Holt, C. (2024) Structure of biomimetic casein micelles: critical tests of the hydrophobic colloid and multivalent-binding models using recombinant deuterated and phosphorylated β-casein. Journal of Structural Biology: X, 9, 100096. (doi: 10.1016/j.yjsbx.2024.100096) (PMID:38318529) (PMCID:PMC10840362)
Rennie, M. L. , Gundogdu, M., Arkinson, C., Liness, S., Frame, S. and Walden, H. (2024) Structural and biochemical insights on the mechanism of action of the clinical USP1 inhibitor, KSQ-4279. Journal of Medicinal Chemistry, (doi: 10.1021/acs.jmedchem.4c01184) (PMID:39190802) (Early Online Publication)
Rezig, I. M., Yaduma, W. G. and McInerny, C. J. (2024) Processes controlling the contractile ring during cytokinesis in fission yeast including the role of ESCRT proteins. Journal of Fungi, 10(2), 154. (doi: 10.3390/jof10020154)
Ruiz de Sabando, A., Ciosi, M. , Galbete, A., Cumming, S. A., Spanish HD Collaborative Group, , Monckton, D. G. and Ramos-Arroyo, M. A. (2024) Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European Journal of Human Genetics, (doi: 10.1038/s41431-024-01546-6)
Salt, I. P. and Carling, D. (2024) A special issue of Essays in Biochemistry on AMPK and AMPK-related kinases. Essays In Biochemistry, (Accepted for Publication)
Schofield, C., Sarrigiannidis, S., Moran-Horowich, A., Jackson, E., Rodrigo-Navarro, A. , Van Agtmael, T. , Cantini, M. , Dalby, M. J. and Salmeron-Sanchez, M. (2024) An in vitro model of the blood-brain barrier for the investigation and isolation of the key drivers of barriergenesis. Advanced Healthcare Materials, (doi: 10.1002/adhm.202303777) (PMID:39101628) (Early Online Publication)
Selman, C. (2024) The dietary exposome: a brief history of diet, longevity and age-related health in rodents. Clinical Science, 138(21), pp. 1343-1356. (doi: 10.1042/CS20241248) (PMID:39444221)
Shahzad, Z. et al. (2024) Protein kinase SnRK2. 4 is a key regulator of aquaporins and root hydraulics in Arabidopsis. Plant Journal, 117(1), pp. 264-279. (doi: 10.1111/tpj.16494) (PMID:37844131)
Sidky, A. M., Viera Melo, A. R., Kay, T. T., Raposo, M., Lima, M. and Monckton, D. (2024) Age-dependent somatic expansion of the ATXN3 CAG repeat in the blood and buccal swab DNA of individuals with spinocerebellar ataxia type 3/Machado-Joseph disease. Human Genetics, (doi: 10.1007/s00439-024-02698-7) (Early Online Publication)
Silva-Alvim, F. A.L., Alvim, J. C., Harvey, A. and Blatt, M. R. (2024) Speedy stomata of a C4 plant correlate with enhanced K+ channel gating. Plant, Cell and Environment, 47(3), pp. 817-831. (doi: 10.1111/pce.14775) (PMID:38013592) (PMCID:PMC10953386)
Su, J. et al. (2024) Overexpression of tonoplast Ca2+‐ATPase in guard cells synergistically enhances stomatal opening and drought tolerance. Journal of Integrative Plant Biology, (doi: 10.1111/jipb.13721) (PMID:38923303) (Early Online Publication)
Tikhonova, I., Zhang, X., Guseinov, A.-A., Jenkins, L. , Li, K., Milligan, G. and Zhang, C. (2024) Structural basis for the ligand recognition and signaling of free fatty acid receptors. Science Advances, 10(2), eadj2384. (doi: 10.1126/sciadv.adj2384) (PMID:38198545)
Tobias, E. S. et al. (2024) SEC31A may be associated with pituitary hormone deficiency and gonadal dysgenesis. Endocrine, 84, pp. 345-349. (doi: 10.1007/s12020-024-03701-x) (PMID:38400880)
Tokatlidis, K. (2024) MIMAS is a new giant multifunctional player in the mitochondrial megacomplex playground. Cell Reports, 43(3), 113874. (doi: 10.1016/j.celrep.2024.113874) (PMID:38386551)
Vosbein, P., Paredes Vergara, P., Huang, D. T. and Thomson, D. (2024) AlphaFold ensemble competition screens enable peptide binder design with single-residue sensitivity. ACS Chemical Biology, (doi: 10.1021/acschembio.4c00418) (Early Online Publication)
Vosbein, P., Vergara, P. P., Huang, D. T. and Thomson, A. R. (2024) An engineered ubiquitin binding coiled coil peptide. Chemical Science, 15(38), pp. 15776-15782. (doi: 10.1039/d4sc04204b) (PMID:39268210)
Waghmare, S. , Xia, L. , Ly, T. P., Xu, J., Farami, S., Burchmore, R. , Blatt, M. R. and Karnik, R. (2024) Arabidopsis Syntaxin of Plants 132 underpins secretory traffic of cargoes associated with salicylic acid signalling and pathogen defence. Plant Physiology, (Accepted for Publication)
Waghmare, S. , Xia, L. , Phan Ly, T., Xu, J., Farami, S., Burchmore, R. , Blatt, M. R. and Karnik, R. (2024) SYNTAXIN OF PLANTS 132 underpins secretion of cargoes associated with salicylic acid signaling and pathogen defense. Plant Physiology, (doi: 10.1093/plphys/kiae541) (In Press)
Williams, J. A. et al. (2024) Developing and investigating a nanovibration intervention for the prevention/reversal of bone loss following spinal cord injury. ACS Nano, 18(27), pp. 17630-17641. (doi: 10.1021/acsnano.4c02104) (PMID:38924391) (PMCID:PMC11238619)
Woodling, N. (2024) Sex- and strain-dependent effects of ageing on sleep and activity patterns in Drosophila. PLoS ONE, 19(8), e0308652. (doi: 10.1371/journal.pone.0308652) (PMID:39150918) (PMCID:PMC11329114)
Wu, Y.‐L., Zhu, A.‐Q., Zhou, X.‐T., Zhang, K.‐W., Yuan, X.‐J., Yuan, M., He, J., Pineda, M. A. and Li, K.‐P. (2024) A novel ultrafiltrate extract of propolis exerts anti‐inflammatory activity through metabolic rewiring. Chemistry and Biodiversity, 21(3), e202301315. (doi: 10.1002/cbdv.202301315) (PMID:38189169)
Yaduma, W. G., Rezig, I. M., Gould, G. W. and McInerny, C. J. (2024) Phosphorylation of anillin/Mid1p in fission yeast regulates its sub-cellular distribution and is required for cytokinesis. Cell Cycle, (Accepted for Publication)
Young, P., Greer, A. I.M. , Smith, C.-A. , Silverwood, R., Tsimbouri, P. M. , Meek, D., Goodyear, C., Gadegaard, N. and Dalby, M. J. (2024) Titanium surface synergy: strontium incorporation and controlled disorder nanotopography optimise osteoinduction. ACS Applied Materials and Interfaces, (doi: 10.1021/acsami.4c04117) (Early Online Publication)
Book Sections
Carver, J. A. and Holt, C. (2024) Current concepts of casein and casein micelle structure, interactions, and dynamics. In: El-Bakry, M. and Mehta, B. M. (eds.) Casein: Structural Properties, Uses, Health Benefits and Nutraceutical Applications. Academic Press, pp. 63-98. ISBN 9780443158360 (doi: 10.1016/B978-0-443-15836-0.00002-0)
2023
Articles
Abioye, J., Lawson‐Williams, M., Lecanda, A., Calhoon, B., McQue, A. L., Colloms, S. D. , Stark, W. M. and Olorunniji, F. J. (2023) High fidelity one‐pot DNA assembly using orthogonal serine integrases. Biotechnology Journal, 18(3), 2200411. (doi: 10.1002/biot.202200411) (PMID:36504358)
Adam, S., Zheng, D., Klein, A., Volz, C., Mullen, W. , Shirran, S. L., Smith, B. O. , Kalinina, O. V., Müller, R. and Koehnke, J. (2023) Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis. Nature Chemistry, 15(4), pp. 560-568. (doi: 10.1038/s41557-023-01153-w) (PMID:36894702) (PMCID:PMC10070186)
Agirre, J. et al. (2023) The CCP 4 suite: integrative software for macromolecular crystallography. Acta Crystallographica. Section D: Structural Biology, D79(6), pp. 449-461. (doi: 10.1107/S2059798323003595)
Alam, S., Gu, Y., Reichert, P. , Bähler, J. and Oliferenko, S. (2023) Optimization of energy production and central carbon metabolism in a non-respiring eukaryote. Current Biology, 33(11), 2175-2186.e5. (doi: 10.1016/j.cub.2023.04.046) (PMID:37164017)
Alqahtani, S., Butcher, M. C., Ramage, G. , Dalby, M. J. , McLean, W. and Nile, C. J. (2023) Acetylcholine receptors in mesenchymal stem cells. Stem Cells and Development, 32(3-4), pp. 47-59. (doi: 10.1089/scd.2022.0201) (PMID:36355611)
Alvim, J. C. et al. (2023) The K/HDEL receptor does not recycle but instead acts as a Golgi-gatekeeper. Nature Communications, 14, 1612. (doi: 10.1038/s41467-023-37056-0) (PMID:36959220) (PMCID:PMC10036638)
Antoniou-Kourounioti, R. L. et al. (2023) Integrating analog and digital modes of gene expression at Arabidopsis FLC. eLife, 12, e79743. (doi: 10.7554/elife.79743) (PMID:37466633) (PMCID:PMC10356135)
Arora, S. et al. (2023) A wheat kinase and immune receptor form host-specificity barriers against the blast fungus. Nature Plants, 9(3), pp. 385-392. (doi: 10.1038/s41477-023-01357-5) (PMID:36797350)
Auge, G., Hankofer, V., Groth, M., Antoniou-Kourounioti, R. , Ratikainen, I. and Lampei, C. (2023) Plant environmental memory: implications, mechanisms, and opportunities for plant scientists and beyond. AoB Plants, 15(4), plad032. (doi: 10.1093/aobpla/plad032) (PMID:37415723) (PMCID:PMC10321398)
Baptista, B. G., Fanton, S., Ribeiro, M., Cardozo, L. F.M.F., Regis, B., Alvarenga, L., Ribeiro-Alves, M., Berretta, A. A., Shiels, P. G. and Mafra, D. (2023) The effect of Brazilian green propolis extract on inflammation in patients with chronic kidney disease on peritoneal dialysis: a randomised double-blind controlled clinical trial. Phytomedicine, 114, 154731. (doi: 10.1016/j.phymed.2023.154731) (PMID:36934668)
Barki, N. et al. (2023) Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner. eLife, 12, RP91861. (doi: 10.7554/eLife.91861) (PMID:38085667) (PMCID:PMC10715726)
Benoit, J. B., McCluney, K. E., DeGennaro, M. J. and Dow, J. A.T. (2023) Dehydration dynamics in terrestrial arthropods: from water sensing to trophic interactions. Annual Review of Entomology, 68(1), pp. 129-149. (doi: 10.1146/annurev-ento-120120-091609) (PMID:36270273) (PMCID:PMC9936378)
Blanco-Melo, D., Campbell, M. A., Zhu, H., Dennis, T. P.W., Modha, S. , Lytras, S., Hughes, J. , Gatseva, A. and Gifford, R. J. (2023) A novel approach to exploring the dark genome and its application to mapping of the vertebrate virus ‘fossil record’. bioRxiv, (doi: 10.1101/2023.10.17.562709)
Bremner-Hart, S. K. , Berends, R., Kaupisch, A., Roccisana, J., Sutherland, C., Bryant, N. J. and Gould, G. W. (2023) Phosphorylation of the N-terminus of Syntaxin-16 controls interaction with mVps45 and GLUT4 trafficking in adipocytes. PeerJ, 11, e15630. (doi: 10.7717/peerj.15630) (PMID:37520260) (PMCID:PMC10373645)
Busch, C., Mulholland, T., Zagnoni, M., Dalby, M. , Berry, C. and Wheadon, H. (2023) Overcoming BCR::ABL1 dependent and independent survival mechanisms in chronic myeloid leukaemia using a multi-kinase targeting approach. Cell Communication and Signaling, 21, 342. (doi: 10.1186/s12964-023-01363-2) (PMID:38031192) (PMCID:PMC10685629)
Cannone, G., Kompaniiets, D., Graham, S., White, M. F. and Spagnolo, L. (2023) Structure of the Saccharolobus solfataricus type III-D CRISPR effector. Current Research in Structural Biology, 5, 100098. (doi: 10.1016/j.crstbi.2023.100098) (PMID:36843655) (PMCID:PMC9945777)
Carrozza, M.-L., Niewiadomska, A.-M., Mazzei, M., Abi-Said, M. R., Hue, S., Hughes, J. , Gatseva, A. and Gifford, R. J. (2023) Emergence and pandemic spread of small ruminant lentiviruses. Virus Evolution, 9(1), vead005. (doi: 10.1093/ve/vead005) (PMID:36793939) (PMCID:PMC9924038)
Castejon-Vega, B. , Cordero, M. D. and Sanz, A. (2023) How the disruption of mitochondrial redox signalling contributes to ageing. Antioxidants, 12(4), 831. (doi: 10.3390/antiox12040831) (PMID:37107206) (PMCID:PMC10135186)
Catterson, J. H. et al. (2023) Protein retention in the endoplasmic reticulum rescues Aβ toxicity in Drosophila. Neurobiology of Aging, 132, pp. 154-174. (doi: 10.1016/j.neurobiolaging.2023.09.008) (PMID:37837732)
Chan, K. L., Lo, C. K.M., Chen, X.-Y., Ip, P., Leung, W. C., Shiels, P. G. , Pell, J. P. , Minnis, H. and Ho, F. K. (2023) Association between intimate partner violence and leukocyte telomere length: a retrospective cohort study of 144,049 UK Biobank participants. Epidemiology and Psychiatric Sciences, 32, e26. (doi: 10.1017/S2045796023000112) (PMCID:PMC10130734)
Ciba, M., Dibnah, B., Hudson, B. D. and Ulven, E. R. (2023) Development and characterization of potent succinate receptor fluorescent tracers. Journal of Medicinal Chemistry, 66(13), pp. 8951-8974. (doi: 10.1021/acs.jmedchem.3c00552) (PMID:37318348)
Craven, H., Erlandsson, H., McGuinness, D., McGuinness, D. , Mafra, D., Ijaz, U. Z. , Bergman, P., Shiels, P. G. and Stenvinkel, P. (2023) A normative microbiome is not restored following kidney transplantation. Clinical Science, 137(20), pp. 1563-1575. (doi: 10.1042/CS20230779) (PMID:37756543)
Cullen, B. et al. (2023) Cognitive function in people with familial risk of depression. JAMA Psychiatry, 80(6), pp. 610-620. (doi: 10.1001/jamapsychiatry.2023.0716) (PMID:37074691) (PMCID:PMC10116387)
Cupellini, L., Qian, P., Nguyen-Phan, T. C., Gardiner, A. T. and Cogdell, R. J. (2023) Quantum chemical elucidation of a sevenfold symmetric bacterial antenna complex. Photosynthesis Research, 156(1), pp. 75-87. (doi: 10.1007/s11120-022-00925-8) (PMID:35672557) (PMCID:PMC10070313)
Dean, B., Bakker, G., Ueda, H. R., Tobin, A. B. , Brown, A. and Kanaan, R. A. A. (2023) A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia. Frontiers in Cellular Neuroscience, 17, 1124333. (doi: 10.3389/fncel.2023.1124333) (PMID:36909280) (PMCID:PMC9992992)
Deni, I. et al. (2023) Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. Cell Chemical Biology, 30(5), 470-485.e6. (doi: 10.1016/j.chembiol.2023.03.002) (PMID:36963402) (PMCID:PMC10198959)
Dhawan, U. , Wang, W.-L., Lin, Y.-C., Yang, R.-B., Dalby, M. J. , Salmeron-Sanchez, M. and Yu, H.-h. (2023) Mechanostimulation-induced integrin αvβ6 and latency associated peptide coupling activates TGF-β and regulates cancer metastasis and stemness. Nano Today, 50, 101882. (doi: 10.1016/j.nantod.2023.101882)
Dobson, A. , Voigt, S., Kumpitsch, L., Langer, L., Voigt, E., Ibrahim, R., Dowling, D. and Reinhardt, K. (2023) Mitonuclear interactions shape both direct and parental effects of diet on fitness, and involve a SNP in mitoribosomal 16s rRNA. PLoS Biology, 21(8), e3002218. (doi: 10.1371/journal.pbio.3002218) (PMID:37603597) (PMCID:PMC10441796)
Donnelly, H. , Kurjan, A., Yong, L. Y., Xiao, Y., Lemgruber, L. , West, C., Salmeron-Sanchez, M. and Dalby, M. J. (2023) Fibronectin matrix assembly and TGFβ1 presentation for chondrogenesis of patient derived pericytes for microtia repair. Biomaterials Advances, 148, 213370. (doi: 10.1016/j.bioadv.2023.213370) (PMID:36931082)
Donnelly, H. , Mandrou, E. and Insall, R. (2023) Sinking while you swim: a dual role for CCR7 in leukocyte migration. Science Immunology, 8(87), eadj3102. (doi: 10.1126/sciimmunol.adj3102) (PMID:37656778)
Donnelly, H. , Sprott, M. R. , Poudel, A., Campsie, P., Childs, P., Reid, S., Salmeron-Sanchez, M. and Biggs, M. (2023) Surface modified piezoelectric co-polymer poly (vinylidene fluoride-trifluoroethylene) supports physiological extracellular matrices to enhance mesenchymal stem cell adhesion for nanoscale mechanical stimulation. ACS Applied Materials and Interfaces, 15(44), pp. 50652-50662. (doi: 10.1021/acsami.3c05128) (PMID:37718477) (PMCID:PMC10636716)
Dornan, A. J. , Halberg, K. V., Beuter, L.-K., Davies, S. A. and Dow, J. A.T. (2023) Compromised junctional integrity phenocopies age-dependent renal dysfunction in Drosophila Snakeskin mutants. Journal of Cell Science, 136(19), jcs261118. (doi: 10.1242/jcs.261118) (PMID:37694602) (PMCID:PMC10565245)
Dowsett, L. , Duluc, L., Higgins, E., Alghamdi, F., Fast, W., Salt, I. P. and Leiper, J. (2023) Asymmetric dimethylarginine positively modulates calcium-sensing receptor signalling to promote lipid accumulation. Cellular Signalling, 107, 110676. (doi: 10.1016/j.cellsig.2023.110676) (PMID:37028778)
Duncan, E., Vita, L., Dibnah, B. and Hudson, B. D. (2023) Metabolite sensing GPCRs controlling interactions between adipose tissue and inflammation. Frontiers in Endocrinology, 14, 1197102. (doi: 10.3389/fendo.2023.1197102) (PMID:37484963) (PMCID:PMC10357040)
Durrani, Z., Kinnaird, J., Cheng, C. W., Brühlmann, F., Capewell, P. , Jackson, A., Larcombe, S., Olias, P., Weir, W. and Shiels, B. (2023) A parasite DNA binding protein with potential to influence disease susceptibility acts as an analogue of mammalian HMGA transcription factors. PLoS ONE, 18(6), e0286526. (doi: 10.1371/journal.pone.0286526) (PMID:37276213) (PMCID:PMC10241358)
Fullerton, J. , Bettencourt, C., Daniels, M., Mclean, F., Simpson, S., Smith, A., Woodling, N. and Kerr, F. (2023) Creating connections: developing an online space for cross-regional mentorship and network building in the dementia research field. Health Open Research, 4, 22. (doi: 10.12688/amrcopenres.13091.2) (PMID:37323472) (PMCID:PMC7614661)
Gala, D. S., Titlow, J. S., Teodoro, R. O. and Davis, I. (2023) Far from home: the role of glial mRNA localization in synaptic plasticity. RNA, 29(2), pp. 153-169. (doi: 10.1261/rna.079422.122) (PMID:36442969) (PMCID:PMC9891262)
Gallusci, P., Agius, D. R., Moschou, P. N., Dobránszki, J., Kaiserli, E. and Martinelli, F. (2023) Deep inside the epigenetic memories of stressed plants. Trends in Plant Science, 28(2), pp. 142-153. (doi: 10.1016/j.tplants.2022.09.004) (PMID:36404175)
Ganguly, A. et al. (2023) G protein-receptor kinases 5/6 are the key regulators of G protein-coupled receptor 35-arrestin interactions. Journal of Biological Chemistry, 299(10), 105218. (doi: 10.1016/j.jbc.2023.105218) (PMID:37660910) (PMCID:PMC10520886)
Garcia-Moreno, M. et al. (2023) Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection. bioRxiv, (doi: 10.1101/2023.06.14.544764)
Gould, E. et al. (2023) Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology. EcoEvoRxiv, (doi: 10.32942/X2GG62)
Harris, C. J., Amtmann, A. and Ton, J. (2023) Epigenetic processes in plant stress priming: open questions and new approaches. Current Opinion in Plant Biology, 75, 102432. (doi: 10.1016/j.pbi.2023.102432) (PMID:37523900)
Hill, C. et al. (2023) Differential methylation of telomere-related genes is associated with kidney disease in individuals with type 1 diabetes. Genes, 14(5), 1029. (doi: 10.3390/genes14051029) (PMID:37239390) (PMCID:PMC10217816)
Hobson, S., Arefin, S., Witasp, A., Hernandez, L., Kublickiene, K., Shiels, P.G. and Stenvinkel, P. (2023) Accelerated vascular aging in chronic kidney disease: the potential for novel therapies. Circulation Research, 132(8), pp. 950-969. (doi: 10.1161/CIRCRESAHA.122.321751) (PMID:37053277)
Horiuchi, K., Uragami, C., Tao, R., Kosumi, D., Cogdell, R. J. and Hashimoto, H. (2023) Excited-state dynamics of all the mono-cis and the major di-cis isomers of β-apo-8′-carotenal as revealed by femtosecond time-resolved transient absorption spectroscopy. Molecules, 28(11), 4424. (doi: 10.3390/molecules28114424) (PMID:37298900) (PMCID:PMC10254598)
Hu, Q. et al. (2023) Universal adaptive optics for microscopy through embedded neural network control [v.3]. arXiv,
Hu, Q. et al. (2023) Universal adaptive optics for microscopy through embedded neural network control. Light: Science and Applications, 12, 270. (doi: 10.1038/s41377-023-01297-x) (PMID:37953294) (PMCID:PMC10641083)
Ishak, M. I., Eales, M., Damiati, L., Liu, X., Jenkins, J., Dalby, M. J. , Nobbs, A. H., Ryadnov, M. G. and Su, B. (2023) Enhanced and stem-cell-compatible effects of nature-inspired antimicrobial nanotopography and antimicrobial peptides to combat implant-associated infection. ACS Applied Nano Materials, 6(4), pp. 2549-2559. (doi: 10.1021/acsanm.2c04913) (PMCID:PMC9972347)
Jaffery, H. et al. (2023) IĸB Protein BCL3 as a controller of osteogenesis and bone health. Arthritis and Rheumatology, 75(12), 2148-2160-2148-2160. (doi: 10.1002/art.42639) (PMID:37410754)
James, A. B. , Sharples, C., Laird, J., Armstrong, E. M., Guo, W., Tzioutziou, N., Zhang, R., Brown, J. W.S., Nimmo, H. and Jones, M. (2023) REVEILLE2 thermosensitive splicing: a molecular basis for the integration of nocturnal temperature information by the Arabidopsis circadian clock. New Phytologist, (doi: 10.1111/nph.19339) (PMID:37897048) (Early Online Publication)
Javitt, A. et al. (2023) The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC. Nature Cancer, 4(5), pp. 629-647. (doi: 10.1038/s43018-023-00557-4) (PMID:37217651)
Jezek, M., Allan, A. C., Jones, J. J. and Geilfus, C.‐M. (2023) Why do plants blush when they are hungry? New Phytologist, 239(2), pp. 494-505. (doi: 10.1111/nph.18833) (PMID:36810736)
Kalita, M. et al. (2023) PET imaging of innate immune activation using 11C radiotracers targeting GPR84. JACS Au, 3(12), pp. 3297-3310. (doi: 10.1021/jacsau.3c00435) (PMID:38155640) (PMCID:PMC10751761)
Kalogeropoulu, S. K., Rauch-Schmücking, H., Lloyd, E. J., Stenvinkel, P., Shiels, P. G. , Johnson, R. J., Fröbert, O., Redtenbacher, I., Burgener, I. A. and Painer-Gigler, J. (2023) Formerly bile-farmed bears as a model of accelerated ageing. Scientific Reports, 13, 9691. (doi: 10.1038/s41598-023-36447-z) (PMID:37322151) (PMCID:PMC10272202)
Kay, S. P.J. and Leonard, D. A. (2023) Hand transplantation: can we balance the risks and benefits? Journal of Hand Surgery (European Volume), 48(3), pp. 208-213. (doi: 10.1177/17531934221132665) (PMID:36638129) (PMCID:PMC9996778)
Leader, D. P. and Milner-White, E. J. (2023) The conserved crown bridge loop at the catalytic centre of enzymes of the haloacid dehalogenase superfamily. Current Research in Structural Biology, 6, 100105. (doi: 10.1016/j.crstbi.2023.100105) (PMID:37786806) (PMCID:PMC10541634)
Leighton, D. J. et al. (2023) Genotype–phenotype characterisation of long survivors with motor neuron disease in Scotland. Journal of Neurology, 270(3), pp. 1702-1712. (doi: 10.1007/s00415-022-11505-0) (PMID:36515702) (PMCID:PMC9971124)
Lemonidis, K. , Rennie, M. L. , Arkinson, C., Chaugule, V. K. , Clarke, M. , Streetley, J. and Walden, H. (2023) Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination. EMBO Journal, 42(3), e111898. (doi: 10.15252/embj.2022111898) (PMID:36385258) (PMCID:PMC9890228)
Madsen, M. A., Semerdzhiev, S., Twigg, J. D., Moss, C., Bavington, C. D. and Amtmann, A. (2023) Environmental modulation of exopolysaccharide production in the cyanobacterium Synechocystis 6803. Applied Microbiology and Biotechnology, 107, pp. 6121-6134. (doi: 10.1007/s00253-023-12697-9) (PMID:37552253) (PMCID:PMC10485101)
Magan, A. A., Radhakrishnan, G. T., Kayani, B., Ronca, F., Khanduja, V., Meek, R. M.D. and Haddad, F. S. (2023) Time for return to sport following total hip arthroplasty: a meta-analysis. HIP International, 33(2), pp. 221-230. (doi: 10.1177/11207000211041975) (PMID:34538122)
Mangione, F., Titlow, J., Maclachlan, C., Gho, M., Davis, I. , Collinson, L. and Tapon, N. (2023) Co-option of epidermal cells enables touch sensing. Nature Cell Biology, 25(4), pp. 540-549. (doi: 10.1038/s41556-023-01110-2) (PMID:36959505) (PMCID:PMC10104782)
Marshall, W. G. et al. (2023) Bioengineering an osteoinductive treatment for bone healing disorders: a small animal case series. VCOT Open, 6(1), e41-e51. (doi: 10.1055/s-0043-1762900)
Martin, T. P. et al. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119(16), 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107) (PMID:37433039) (PMCID:PMC10730241)
McInnes, K. J., van der Hooft, J. J.J. , Sharma, A., Herzyk, P. , Hundleby, P. A.C., Schoonbeek, H.-J., Amtmann, A. , Ridout, C. and Jenkins, G. I. (2023) Overexpression of Brassica napus COMT1 in Arabidopsis heightens UV-B-mediated resistance to Plutella xylostella herbivory. Photochemical and Photobiological Sciences, 22, pp. 2341-2356. (doi: 10.1007/s43630-023-00455-9) (PMID:37505444) (PMCID:PMC10509076)
Meda Venkata, S. P., Li, H., Xu, L., Koh, J. Y., Nguyen, H., Minjares, M., Li, C., Kowluru, A., Milligan, G. and Wang, J.-M. (2023) Inhibition of GPR39 restores defects in endothelial cell–mediated neovascularization under the duress of chronic hyperglycemia: evidence for regulatory roles of the sonic hedgehog signaling axis. Proceedings of the National Academy of Sciences of the United States of America, 120(1), e2208541120. (doi: 10.1073/pnas.2208541120) (PMID:36574661) (PMCID:PMC9910611)
Milligan, G. (2023) GPR35: from enigma to therapeutic target. Trends in Pharmacological Sciences, 44(5), pp. 263-273. (doi: 10.1016/j.tips.2023.03.001) (PMID:37002007)
Montaño, S. P., Rowland, S.-J., Fuller, J. R., Burke, M. E., MacDonald, A. I., Boocock, M. R., Stark, W. M. and Rice, P. A. (2023) Structural basis for topological regulation of Tn3 resolvase. Nucleic Acids Research, 51(3), pp. 1001-1018. (doi: 10.1093/nar/gkac733) (PMID:36100255) (PMCID:PMC9943657)
Morales, F. et al. (2023) Individual-specific levels of CTG•CAG somatic instability are shared across multiple tissues in myotonic dystrophy type 1. Human Molecular Genetics, 32(4), pp. 621-631. (doi: 10.1093/hmg/ddac231) (PMID:36099027)
Morata-Martínez, M., Sprott, M. R. , Antolinos-Turpín, C. M., Salmeron-Sanchez, M. and Gallego-Ferrer, G. (2023) Fine-tuning regulation of surface mobility by acrylate copolymers and its effect on cell adhesion and differentiation. ACS Applied Bio Materials, 6(5), pp. 1755-1762. (doi: 10.1021/acsabm.2c01053) (PMID:37067245) (PMCID:PMC10189726)
Moreira, L. d. S. G., Brum, I. d. S. d. C., de Vargas Reis, D. C.M., Trugilho, L., Chermut, T. R., Esgalhado, M., Cardozo, L. F.M.F., Stenvinkel, P., Shiels, P. G. and Mafra, D. (2023) Cinnamon: an aromatic condiment applicable to chronic kidney disease. Kidney Research and Clinical Practice, 42(1), pp. 4-26. (doi: 10.23876/j.krcp.22.111) (PMID:36747357) (PMCID:PMC9902738)
Naseem, M. T., Beaven, R., Koyama, T., Naz, S., Su, S.-y., Leader, D. P. , A. Klaerke, D., Calloe, K., Denholm, B. and Halberg, K. V. (2023) NHA1 is a cation/proton antiporter essential for the water-conserving functions of the rectal complex in Tribolium castaneum. Proceedings of the National Academy of Sciences of the United States of America, 120(13), e221708412. (doi: 10.1073/pnas.2217084120) (PMID:36943876)
Neuhaus, M. et al. (2023) EHD2 regulates plasma membrane integrity and downstream insulin receptor signaling events. Molecular Biology of the Cell, 34(12), ar124. (doi: 10.1091/mbc.e23-03-0078) (PMID:37703099) (PMCID:PMC10846623)
Neytchev, O. et al. (2023) Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageing. Journal of Internal Medicine, 295(1), pp. 79-90. (doi: 10.1111/joim.13724)
Nguyen, T.-H. , Silva-Alvim, F. A. L., Hills, A. and Blatt, M. R. (2023) OnGuard3e: a predictive, ecophysiology‐ready tool for gas exchange and photosynthesis research. Plant, Cell and Environment, 46(11), pp. 3644-3658. (doi: 10.1111/pce.14674) (PMID:37498151)
Nguyen, T. B.-A. , Lefoulon, C., Nguyen, T.-H. , Blatt, M. R. and Carroll, W. (2023) Engineering stomata for enhanced carbon capture and water-use efficiency. Trends in Plant Science, 28(11), pp. 1290-1309. (doi: 10.1016/j.tplants.2023.06.002) (PMID:37423785)
Omale, S., Amagon, K., Johnson, T. O., Kennedy Bremner-Hart, S. and Gould, G. (2023) A systematic analysis of anti-diabetic medicinal plants from cells to clinical trials. PeerJ, 11, e14639. (doi: 10.7717/peerj.14639) (PMID:36627919) (PMCID:PMC9826616)
Ong, H. W., Adderley, J., Tobin, A. B. , Drewry, D. H. and Doerig, C. (2023) Parasite and host kinases as targets for antimalarials. Expert Opinion on Therapeutic Targets, 27(2), pp. 151-169. (doi: 10.1080/14728222.2023.2185511) (PMID:36942408)
Pan, P., Pineda, M. A. , Wang, Y., Khan, A. and Nyirenda, M. H. (2023) Aberrant pro-inflammatory responses of CD20⁺ T cells in experimental arthritis. Cellular Immunology, 387, 104717. (doi: 10.1016/j.cellimm.2023.104717) (PMID:37075620)
Panagiotou, N. , McGuinness, D., Jaminon, A. M.G., Mees, B., Selman, C. , Schurgers, L. and Shiels, P. G. (2023) Microvesicle-mediated tissue regeneration mitigates the effects of cellular ageing. Cells, 12(13), 1707. (doi: 10.3390/cells12131707) (PMID:37443741) (PMCID:PMC10340655)
Perrella, G., Fasano, C., Donald, N. A., Daddiego, L., Fang, W., Martignago, D., Carr, C., Conti, L., Herzyk, P. and Amtmann, A. (2023) Histone Deacetylase Complex 1 and Histone 1 epigenetically moderate stress responsiveness of Arabidopsis thaliana seedlings. New Phytologist, (doi: 10.1111/nph.19165) (PMID:37565540) (Early Online Publication)
Prasetyaningrum, P., Litthauer, S., Vegliani, F., Battle, M. W., Wood, M. W., Liu, X., Dickson, C. and Jones, M. A. (2023) Inhibition of RNA degradation integrates the metabolic signals induced by osmotic stress into the Arabidopsis circadian system. Journal of Experimental Botany, 74(18), pp. 5805-5819. (doi: 10.1093/jxb/erad274) (PMID:37453132) (PMCID:PMC10540740)
Quint, M. et al. (2023) 25 years of thermomorphogenesis research: milestones and perspectives. Trends in Plant Science, 28(10), pp. 1089-1100. (doi: 10.1016/j.tplants.2023.07.001) (PMID:37574427)
Rezig, I. M., Yaduma, W. G., Gould, G. W. and McInerny, C. J. (2023) The role of anillin/Mid1p during medial division and cytokinesis: from fission yeast to cancer cells. Cell Cycle, 22(6), pp. 633-644. (doi: 10.1080/15384101.2022.2147655) (PMID:36426865) (PMCID:PMC9980708)
Robinson, P. J. , Pringle, M. A. , Fleming, B. and Bulleid, N. J. (2023) Distinct role of ERp57 and ERdj5 as a disulfide isomerase and reductase during ER protein folding. Journal of Cell Science, 136(2), jcs260656. (doi: 10.1242/jcs.260656) (PMID:36655611) (PMCID:PMC10022741)
Romero-Torrecilla, J. A. et al. (2023) An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration. npj Regenerative Medicine, 8, 54. (doi: 10.1038/s41536-023-00330-2) (PMID:37773177) (PMCID:PMC10541910)
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
Sabando, A. R. et al. (2023) Spanish HTT gene study reveals haplotype and allelic diversity with possible implications for germline expansion dynamics in Huntington disease. Human Molecular Genetics, 32(6), pp. 897-906. (doi: 10.1093/hmg/ddac224) (PMID:36130218) (PMCID:PMC9990985)
Sahota, V. K., Stone, A., Woodling, N. S. , Spiers, J. G., Steinert, J. R., Partridge, L. and Augustin, H. (2023) Plum modulates Myoglianin and regulates synaptic function in D. melanogaster. Open Biology, 13(9), 230171. (doi: 10.1098/rsob.230171) (PMID:37699519) (PMCID:PMC10497343)
Sanchez-Rubio, A., Jayawarna, V., Maxwell, E., Dalby, M. J. and Salmeron-Sanchez, M. (2023) Keeping it organized: multicompartment constructs to mimic tissue heterogeneity. Advanced Healthcare Materials, 12(17), 2202110. (doi: 10.1002/adhm.202202110) (PMID:36938891)
Sannino, D. R. and Dobson, A. J. (2023) Acetobacter pomorum in the Drosophila gut microbiota buffers against host metabolic impacts of dietary preservative formula and batch variation in dietary yeast. Applied and Environmental Microbiology, 89(10), e0016523. (doi: 10.1128/aem.00165-23) (PMID:37800920) (PMCID:PMC10617557)
Schmidt, T. et al. (2023) eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation. Nucleic Acids Research, 51(4), pp. 1859-1879. (doi: 10.1093/nar/gkad030) (PMID:36727461) (PMCID:PMC9976904)
Shiels, P. G. (2023) ‘Debugging’ heart failure. Journal of Internal Medicine, 294(4), pp. 374-376. (doi: 10.1111/joim.13691) (PMID:37424184)
Simkin, A. J., Alqurashi, M., Lopez-Calcagno, P. E., Headland, L. R. and Raines, C. A. (2023) Glyceraldehyde-3-phosphate dehydrogenase subunits A and B are essential to maintain photosynthetic efficiency. Plant Physiology, (doi: 10.1093/plphys/kiad256) (PMID:37099455) (Early Online Publication)
Sonam, S., Malmstrom, J., Kamei, K.-i. and Dalby, M. J. (2023) Editorial: Materials for mechanotransduction and beyond. Frontiers in Cell and Developmental Biology, 11, 1222957. (doi: 10.3389/fcell.2023.1222957) (PMID:37305678) (PMCID:PMC10250702)
Thompson, M. K., Ceccarelli, A., Ish-Horowicz, D. and Davis, I. (2023) Dynamically regulated transcription factors are encoded by highly unstable mRNAs in the Drosophila larval brain. RNA, 29(7), pp. 1020-1032. (doi: 10.1261/rna.079552.122) (PMID:37041032) (PMCID:PMC10275270)
Titlow, J. S. et al. (2023) Systematic analysis of YFP traps reveals common mRNA/protein discordance in neural tissues. Journal of Cell Biology, 222(6), e202205129. (doi: 10.1083/jcb.202205129) (PMID:37145332) (PMCID:PMC10165541)
Trovato, M., Brini, F., Mseddi, K., Rhizopoulou, S. and Jones, M. A. (2023) A holistic and sustainable approach linked to drought tolerance of Mediterranean crops. Frontiers in Plant Science, 14, 1167376. (doi: 10.3389/fpls.2023.1167376) (PMID:37396645) (PMCID:PMC10308116)
Valentini, A., Schultz-Knudsen, K., Højgaard Hansen, A., Tsakoumagkou, A., Jenkins, L. , Christensen, H. B., Manandhar, A., Milligan, G. , Ulven, T. and Rexen Ulven, E. (2023) Discovery of potent tetrazole free fatty acid receptor 2 antagonists. Journal of Medicinal Chemistry, 66(9), pp. 6105-6121. (doi: 10.1021/acs.jmedchem.2c01935) (PMID:37129317)
Vitale, M., Sanz, A. and Scialò, F. (2023) Mitochondrial redox signaling: a key player in aging and disease. Aging, (doi: 10.18632/aging.204659) (PMID:37052982) (Early Online Publication)
Vuckovic, Z. et al. (2023) Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics. eLife, 12, e83477. (doi: 10.7554/elife.83477) (PMID:37248726) (PMCID:PMC10229135)
Waksman, T., Suetsugu, N., Hermanowicz, P., Ronald, J. , Sullivan, S. , Łabuz, J. and Christie, J. M. (2023) Phototropin phosphorylation of ROOT PHOTOTROPISM 2 and its role in mediating phototropism, leaf positioning and chloroplast accumulation movement in arabidopsis. Plant Journal, 114(2), pp. 390-402. (doi: 10.1111/tpj.16144) (PMID:36794876)
Wang, J. et al. (2023) Deep super-resolution imaging of thick tissue using structured illumination with adaptive optics. bioRxiv, (doi: 10.1101/2023.12.21.572818)
Wood, M. , Neumann, R., Roy, P., Nair, V. and Royle, N. (2023) Characterization of integrated Marek’s disease virus genomes supports a model of integration by homology-directed recombination and telomere-loop-driven excision. Journal of Virology, 97(10), e0071623. (doi: 10.1128/jvi.00716-23) (PMID:37737586) (PMCID:PMC10617522)
Wright, T. A., Gemmell, A. O., Tejeda, G. S. , Blair, C. M. and Baillie, G. S. (2023) Cancer: phosphodiesterase type 4C (PDE4C), the forgotten subfamily as a therapeutic target. International Journal of Biochemistry and Cell Biology, 162, 106453. (doi: 10.1016/j.biocel.2023.106453) (PMID:37499270)
Zhang, J. et al. (2023) Single amino acid change alters specificity of the multi-allelic wheat stem rust resistance locus SR9. Nature Communications, 14, 7354. (doi: 10.1038/s41467-023-42747-9) (PMID:37963867) (PMCID:PMC10645757)
Zhang, X. et al. (2023) Pro-phagocytic function and structural basis of GPR84 signaling. Nature Communications, 14, 5706. (doi: 10.1038/s41467-023-41201-0) (PMID:37709767) (PMCID:PMC10502086)
Zhou, Z. , Lo, C. K.M., Chan, K. L., Chung, R. S.Y., Pell, J. P. , Minnis, H. , Shiels, P. G. , Ip, P. and Ho, F. K. (2023) Child maltreatment and telomere length in middle and older age: retrospective cohort study of 141 748 UK Biobank participants. British Journal of Psychiatry, 223(2), pp. 377-381. (doi: 10.1192/bjp.2023.33) (PMID:36946056)
Book Sections
Donnelly, H. , Vermeulen, S., Tsimbouri, M. and Dalby, M. J. (2023) Cell–material interactions. In: De Boer, J. and Van Blitterswijk, C. A. (eds.) Tissue Engineering. Elsevier, pp. 261-292. ISBN 9780128244593 (doi: 10.1016/B978-0-12-824459-3.00008-1)
Karnik, R. and Blatt, M. R. (2023) Analyzing protein–protein interactions using the split-ubiquitin system. In: Mukhtar, S. (ed.) Protein-Protein Interactions: Methods and Protocols. Series: Methods in molecular biology (2690). Humana Press: New York, NY, pp. 23-36. ISBN 9781071633267 (doi: 10.1007/978-1-0716-3327-4_3)
Queiroz, M. V., Battle, M. W. and Jones, M. A. (2023) Interactions between photosynthesis and the circadian system. In: Sharwood, R. (ed.) Understanding and Improving Crop Photosynthesis. Series: Burleigh Dodds series in agricultural science (130). Burleigh Dodds Science Publishing: Cambridge, UK, pp. 75-92. ISBN 9781801461290
Shiels, P. , Tran, N. , McCavitt, J., Neytchev, O. and Stenvinkel, P. (2023) Chronic kidney disease and the exposome of ageing. In: Harris, J.R. and Korolchuk, V.I. (eds.) Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science. Series: Subcellular biochemistry (103). Springer: Cham, pp. 79-94. ISBN 9783031265754 (doi: 10.1007/978-3-031-26576-1_5)
Conference or Workshop Item
Bremner-Hart, S. (2023) Concept Mapping in Pharmacology: Quantitative Evaluation and Qualitative Reflection. IUPHAR Education Satellite Meeting, Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, 1-2 July 2023.
Bremner-Hart, S. (2023) Evaluating the Benefits of Virtual Laboratory Simulations for Biomolecular Science Students. IUPHAR Education Satellite Meeting, Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, 1-2 July 2023.
Bremner-Hart, S. (2023) Evaluating the Benefits of Virtual Laboratory Simulations for Biomolecular Science Students. NES Annual Virtual Conference 2023, 27-28 April 2023.
Cuahtecontzi Delint, R., Ishak, I., Tsimbouri, M. P. , Jayawarna, V., Nobbs, A., Salmeron-Sanchez, M. , Dalby, M. J. and Su, B. (2023) In-Vitro Studies of 2D Orthopaedic Implants with Cell Instructive Nanotopographies. TERMIS 2023 – European Chapter, Manchester, UK, 28–31 March 2023. (doi: 10.1089/ten.tea.2023.29043.abstract)
Donald, C. et al. (2023) The Impact of using Virtual Reality Lessons to Teach Microbiology Online. 16th Annual University of Glasgow Learning and Teaching Conference, Online, 29 Mar 2023. (Unpublished)
Donald, C. et al. (2023) The Impact of using Virtual Reality Lessons to Teach Microbiology Online. Microbiology Society Annual Conference 2023, Birmingham, UK, 17-20 April 2023. (Unpublished)
Donald, C. et al. (2023) The Impact of using Virtual Reality Lessons to Teach Microbiology Online. SEB Centenary Conference 2023, Edinburgh, UK, 4-7 July 2023. (Unpublished)
Exhibitions
Skeldon, K. et al. (2023) Research Firsts Exhibition. (doi: 10.17605/OSF.IO/ZQC5P) [Exhibitions]
2022
Articles
Alharbi, A. G., Tobin, A. B. and Milligan, G. (2022) How arrestins and GRKs regulate the function of long chain fatty acid receptors. International Journal of Molecular Sciences, 23(20), 12237. (doi: 10.3390/ijms232012237) (PMID:36293091) (PMCID:PMC9602559)
Anderson, H. J., Sahoo, J. K., Wells, J., van Nuffel, S., Dhowre, H. S., Oreffo, R. O.C., Zelzer, M., Ulijn, R. V. and Dalby, M. J. (2022) Cell-controlled dynamic surfaces for skeletal stem cell growth and differentiation. Scientific Reports, 12, 8165. (doi: 10.1038/s41598-022-12057-z) (PMID:35581256) (PMCID:PMC9114122)
Antonijevic, I. A. et al. (2022) Suppression of somatic expansion as a novel therapeutic approach for Huntington disease and other repeat expansion disorders. GEN Biotechnology, 1(2), pp. 163-175. (doi: 10.1089/genbio.2021.0012)
Archibald, L. J., Brown, E. A., Millard, C. J., Watson, P. J., Robertson, N. S., Wang, S., Schwabe, J. W. R. and Jamieson, A. G. (2022) Hydroxamic acid-modified peptide library provides insights into the molecular basis for the substrate selectivity of HDAC corepressor complexes. ACS Chemical Biology, 17(9), pp. 2572-2582. (doi: 10.1021/acschembio.2c00510) (PMID:35973051) (PMCID:PMC9488896)
Baena, G. , Xia, L. , Waghmare, S. and Karnik, R. (2022) SNARE SYP132 mediates divergent trafficking of H+-ATPase AHA1 and antimicrobial PR1 during bacterial pathogenesis. Plant Physiology, 189(3), pp. 1639-1661. (doi: 10.1093/plphys/kiac149) (PMID:35348763) (PMCID:PMC9237740)
Barki, N. et al. (2022) Chemogenetics defines the roles of short chain fatty acid receptors within the gut-brain axis. eLife, 11, e73777. (doi: 10.7554/eLife.73777) (PMID:35229717) (PMCID:PMC8887895)
Bartlome, S. and Berry, C. C. (2022) Recent insights into the effects of metabolism on breast cancer cell dormancy. British Journal of Cancer, 127(8), pp. 1385-1393. (doi: 10.1038/s41416-022-01869-5) (PMID:35715635) (PMCID:PMC9553927)
Black, H. L. et al. (2022) Knockout of Syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion. Journal of Cell Science, 135(1), jcs258375. (doi: 10.1242/jcs.258375) (PMID:34859814) (PMCID:PMC8767277)
Blatt, M. R. , Jezek, M., Lew, V. L. and Hills, A. (2022) What can mechanistic models tell us about guard cells, photosynthesis, and water use efficiency? Trends in Plant Science, 27(2), pp. 166-179. (doi: 10.1016/j.tplants.2021.08.010) (PMID:34565672)
Bremner, S. K. , Al Shammari, W. O., Milligan, R. S., Hudson, B. D. , Sutherland, C., Bryant, N. J. and Gould, G. W. (2022) Pleiotropic effects of Syntaxin16 identified by gene editing in cultured adipocytes. Frontiers in Cell and Developmental Biology, 10, 1033501. (doi: 10.3389/fcell.2022.1033501) (PMID:36467416) (PMCID:PMC9716095)
Budgett, R. F., Bakker, G., Sergeev, E. , Bennett, K. A. and Bradley, S. J. (2022) Targeting the type 5 metabotropic glutamate receptor: a potential therapeutic strategy for neurodegenerative diseases? Frontiers in Pharmacology, 13, 893422. (doi: 10.3389/fphar.2022.893422) (PMID:35645791) (PMCID:PMC9130574)
Butler, L., Locatelli, C., Allagioti, D., Lousa, I., Lemonidis, K. , Tomkinson, N. C.O., Salaun, C. and Chamberlain, L. H. (2022) S-Acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme-substrate interaction. Journal of Biological Chemistry, 299(1), 102754. (doi: 10.1016/j.jbc.2022.102754) (PMID:36442513) (PMCID:PMC9800311)
Caccavale, E., Johnson, M. P., Brijbassi, S., Andreazza, A. C. and Tokatlidis, K. (2022) Mitochondria and Us: from exploration to global collective. Biochemist, 44(4), pp. 22-28. (doi: 10.1042/bio_2022_122)
Caspar, B., Cocchiara, P., Melet, A., Van Emelen, K., Van der Aa, A., Milligan, G. and Herbeuval, J.-P. (2022) CXCR4 as a novel target in immunology: moving away from typical antagonists. Future Drug Discovery, 4(2), FDD77. (doi: 10.4155/fdd-2022-0007) (PMID:35875591) (PMCID:PMC9298491)
Conley, M. J. et al. (2022) Helical ordering of envelope associated proteins and glycoproteins in respiratory syncytial virus. EMBO Journal, 41(3), e109728. (doi: 10.15252/embj.2021109728) (PMID:34935163) (PMCID:PMC8804925)
Cousins, A. et al. (2022) Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways. Leukemia, 36(12), pp. 2903-2907. (doi: 10.1038/s41375-022-01722-x) (PMID:36289348) (PMCID:PMC9712090)
Crawford, C. L. et al. (2022) SARM1 depletion slows axon degeneration in a CNS model of neurotropic viral infection. Frontiers in Molecular Neuroscience, 15, 860410. (doi: 10.3389/fnmol.2022.860410) (PMID:35493328) (PMCID:PMC9043327)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
Dawson, J., Baine-Savanhu, F. K., Ciosi, M. , Maxwell, A. , Monckton, D. G. and Krause, A. (2022) A probable cis-acting genetic modifier of Huntington disease frequent in individuals with African ancestry. Human Genetics and Genomics Advances, 3(4), 100130. (doi: 10.1016/j.xhgg.2022.100130) (PMID:35935919) (PMCID:PMC9352962)
de Carbonnel, M., Stormonth-Darling, J. M., Liu, W., Kuziak, D. and Jones, M. A. (2022) Realising the environmental potential of vertical farming systems through advances in plant photobiology. Biology, 11(6), 922. (doi: 10.3390/biology11060922) (PMID:35741444) (PMCID:PMC9220163)
Dhawan, U. , Jaffery, H., Salmeron-Sanchez, M. and Dalby, M. J. (2022) An ossifying landscape: materials and growth factor strategies for osteogenic signalling and bone regeneration. Current Opinion in Biotechnology, 73, pp. 355-363. (doi: 10.1016/j.copbio.2021.10.010) (PMID:34735985)
Divorty, N., Jenkins, L. , Ganguly, A. , Butcher, A. J., Hudson, B. D. , Schulz, S., Tobin, A. B. , Nicklin, S. A. and Milligan, G. (2022) Agonist-induced phosphorylation of orthologues of the orphan receptor GPR35 functions as an activation sensor. Journal of Biological Chemistry, 298(3), 101655. (doi: 10.1016/j.jbc.2022.101655) (PMID:35101446) (PMCID:PMC8892012)
Dow, J. A.T. , Simons, M. and Romero, M. F. (2022) Drosophila melanogaster: a simple genetic model of kidney structure, function and disease. Nature Reviews Nephrology, 18(7), pp. 417-434. (doi: 10.1038/s41581-022-00561-4) (PMID:35411063)
Duan, H.-G., Jha, A., Chen, L., Tiwari, V., Cogdell, R. J. , Ashraf, K., Prokhorenko, V. I., Thorwart, M. and Miller, R. J. D. (2022) Quantum coherent energy transport in the Fenna–Matthews–Olson complex at low temperature. Proceedings of the National Academy of Sciences of the United States of America, 119(49), e2212630119. (doi: 10.1073/pnas.2212630119) (PMID:36442134) (PMCID:PMC9894199)
Dunkerley, K. M., Rintala-Dempsey, A. C., Salzano, G. , Tadayon, R., Hadi, D., Barber, K. R., Walden, H. and Shaw, G. S. (2022) Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by Parkin. Biochemical Journal, 479(6), pp. 751-766. (doi: 10.1042/bcj20210741) (PMID:35262643) (PMCID:PMC9022993)
Dwomoh, L. et al. (2022) M1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease. Science Signaling, 15(760), eabm3720. (doi: 10.1126/scisignal.abm3720) (PMID:36378750)
Dwomoh, L. , Tejeda, G. S. and Tobin, A. B. (2022) Targeting the M1 muscarinic acetylcholine receptor in Alzheimer’s disease. Neuronal Signaling, 6(1), NS20210004. (doi: 10.1042/NS20210004) (PMID:35571495) (PMCID:PMC9069568)
Elvers, I., Nguyen Phan, T. C., Gardiner, A. T., Hunter, C. N., Cogdell, R. J. and Köhler, J. (2022) Phasor analysis reveals multicomponent fluorescence kinetics in the LH2 complex from Marichromatium purpuratum. Journal of Physical Chemistry B, 126(49), pp. 10335-10346. (doi: 10.1021/acs.jpcb.2c04983) (PMID:36449272)
Eshel, G. et al. (2022) Positive selection and heat‐response transcriptomes reveal adaptive features of the Brassicaceae desert model, Anastatica hierochuntica. New Phytologist, 236(3), pp. 1006-1026. (doi: 10.1111/nph.18411) (PMID:35909295) (PMCID:PMC9804903)
Fang, W., Vellutini, E., Perrella, G. and Kaiserli, E. (2022) TANDEM ZINC-FINGER/PLUS3 regulates phytochrome B abundance and signaling to fine-tune hypocotyl growth. Plant Cell, 34(11), pp. 4213-4231. (doi: 10.1093/plcell/koac236) (PMID:35929801) (PMCID:PMC9614508)
Fullerton, J., Bettencourt, C., Daniels, M., Mclean, F., Simpson, S., Smith, A., Woodling, N. and Kerr, F. (2022) Creating connections: developing an online space for cross-regional mentorship and network building in the dementia research field. AMRC Open Research, 4, 22. (doi: 10.12688/amrcopenres.13091.1)
Gao, X. et al. (2022) Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7. Cell Calcium, 106, 102639. (doi: 10.1016/j.ceca.2022.102639) (PMID:36027648)
Gilroy, J., McInerny, C. , Dudley, S., Balmer, D., Batty, C., Crochet, P.-A., French, P., Golley, M., Lees, A. and Stoddart, A. (2022) British Ornithologists' Union Records Committee (BOURC): 53rd Report (January 2022). Ibis, 164(1), pp. 363-368. (doi: 10.1111/ibi.13014)
Gilroy, J., McInerny, C. , Dudley, S., Batty, C., Crochet, P.-A., French, P., Golley, M., Lees, A. and Stoddart, A. (2022) British Ornithologists’ Union Records Committee (BOURC): 54th Report (July 2022). Ibis, 164(3), pp. 929-931. (doi: 10.1111/ibi.13064)
Gracie, J., Zamberlan, F., Andrews, I. B., Smith, B. O. and Peveler, W. J. (2022) Growth of plasmonic nanoparticles for aging cask-matured whisky. ACS Applied Nano Materials, 5(10), pp. 15362-15368. (doi: 10.1021/acsanm.2c03406) (PMID:36338330)
Graham, C. et al. (2022) Mitochondrial ROS signalling requires uninterrupted electron flow and is lost during ageing in flies. GeroScience, 44(4), pp. 1961-1974. (doi: 10.1007/s11357-022-00555-x) (PMID:35355221) (PMCID:PMC9616974)
Guarino, F. et al. (2022) An epigenetic alphabet of crop adaptation to climate change. Frontiers in Genetics, 13, 818727. (doi: 10.3389/fgene.2022.818727) (PMID:35251130) (PMCID:PMC8888914)
Hamilton, M. J. et al. (2022) Clinical and neuroradiological correlates of sleep in myotonic dystrophy type 1. Neuromuscular Disorders, 32(5), pp. 377-389. (doi: 10.1016/j.nmd.2022.02.003) (PMID:35361525)
Hogrel, G., Guild, A., Graham, S., Rickman, H., Grüschow, S., Bertrand, Q., Spagnolo, L. and White, M. F. (2022) Cyclic nucleotide-induced helical structure activates a TIR immune effector. Nature, 608(7924), pp. 808-812. (doi: 10.1038/s41586-022-05070-9) (PMID:35948638)
Horaruang, W. et al. (2022) Engineering a K+ channel 'sensory antenna' enhances stomatal kinetics, water use efficiency and photosynthesis. Nature Plants, 8(11), pp. 1262-1274. (doi: 10.1038/s41477-022-01255-2) (PMID:36266492)
Horvath, A., Fuxreiter, M., Vendruscolo, M., Holt, C. and Carver, J. A. (2022) Are casein micelles extracellular condensates formed by liquid-liquid phase separation? FEBS Letters, 596(16), pp. 2072-2085. (doi: 10.1002/1873-3468.14449) (PMID:35815989)
Kataura, T. et al. (2022) Autophagy promotes cell survival by maintaining NAD levels. Developmental Cell, 57(22), 2584-2598.e11. (doi: 10.1016/j.devcel.2022.10.008) (PMID:36413951) (PMCID:36413951)
Khordadpour Deilamani, F. and Taghi Akbari, M. (2022) First report of preimplantation genetic diagnosis of mucopolysaccharidoses IVA and HLA typing for hematopoietic stem cell transplantation. Bulletin of the National Research Centre, 46, 283. (doi: 10.1186/s42269-022-00972-0)
Kim, J., Nguyen-Phan, T. C., Gardiner, A. T., Yoon, T. H., Cogdell, R. J. , Cho, M. and Scholes, G. D. (2022) Vibrational modes promoting exciton relaxation in the B850 band of LH2. Journal of Physical Chemistry Letters, 13(4), pp. 1099-1106. (doi: 10.1021/acs.jpclett.1c03868) (PMID:35080414)
Kjeldsen, A. et al. (2022) The fluorescent protein iLOV as a reporter for screening of high‐yield production of antimicrobial peptides in Pichia pastoris. Microbial Biotechnology, 15(7), pp. 2126-2139. (doi: 10.1111/1751-7915.14034) (PMID:35312165) (PMCID:PMC9249318)
Koester, A. M., Geiser, A., Bowman, P. R.T., van de Linde, S., Gadegaard, N. , Bryant, N. J. and Gould, G. W. (2022) GLUT4 translocation and dispersal operate in multiple cell types and are negatively correlated with cell size in adipocytes. Scientific Reports, 12, 20535. (doi: 10.1038/s41598-022-24736-y) (PMID:36446811) (PMCID:PMC9708847)
Koester, A. M. et al. (2022) EFR3 and phosphatidylinositol 4-kinase IIIα regulate insulin-stimulated glucose transport and GLUT4 dispersal in 3T3-L1 adipocytes. Bioscience Reports, 42(7), BSR20221181. (doi: 10.1042/BSR20221181) (PMID:35735144) (PMCID:PMC9272592)
Kowalczyk, D., Nakasone, M. A., Smith, B. O. and Huang, D. T. (2022) Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function. Life Science Alliance, 5(12), e202201472. (doi: 10.26508/lsa.202201472) (PMID:35944929) (PMCID:PMC9366199)
Krause, S. A. , Overend, G. , Dow, J. A.T. and Leader, D. P. (2022) FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas. Nucleic Acids Research, 50(D1), D1010-D1015. (doi: 10.1093/nar/gkab971) (PMID:34718735) (PMCID:PMC8728208)
Ledahawsky, L. M. et al. (2022) The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo. FEBS Journal, 289(13), pp. 3894-3914. (doi: 10.1111/febs.16377) (PMID:35092170) (PMCID:PMC9542548)
Lee, J.-M. et al. (2022) Genetic modifiers of Huntington disease differentially influence motor and cognitive domains. American Journal of Human Genetics, 109(5), pp. 885-899. (doi: 10.1016/j.ajhg.2022.03.004) (PMID:35325614)
Lemonidis, K. , Arkinson, C., Rennie, M. L. and Walden, H. (2022) Mechanism, specificity and function of FANCD2‐FANCI ubiquitination and deubiquitination. FEBS Journal, 289(16), pp. 4811-4829. (doi: 10.1111/febs.16077) (PMID:34137174)
Li, H. et al. (2022) Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly. Science, 375(6584), eabk2432. (doi: 10.1126/science.abk2432) (PMID:35239393) (PMCID:PMC8944923)
Liao, X. and Jenkins, G. I. (2022) Cysteines have a role in conformation of the UVR8 photoreceptor. Plant Journal, 111(2), pp. 583-594. (doi: 10.1111/tpj.15841) (PMID:35608127)
Lieberman-Lazarovich, M., Kaiserli, E. , Bucher, E. and Mladenov, V. (2022) Natural and induced epigenetic variation for crop improvement. Current Opinion in Plant Biology, 70, 102297. (doi: 10.1016/j.pbi.2022.102297) (PMID:36108411)
Livingstone, R. , Bryant, N. J., Boyle, J. G., Petrie, J. R. and Gould, G. W. (2022) Diabetes is accompanied by changes in the levels of proteins involved in endosomal GLUT4 trafficking in obese human skeletal muscle. Endocrinology, Diabetes and Metabolism, 5(5), e361. (doi: 10.1002/edm2.361) (PMID:35964329) (PMCID:PMC9471587)
Lyall, D. M. , Quinn, T. , Lyall, L. M., Ward, J. , Anderson, J. J. , Smith, D. J. , Stewart, W. , Strawbridge, R. J. , Bailey, M. E.S. and Cullen, B. (2022) Quantifying bias in psychological and physical health in the UK Biobank imaging sub-sample. Brain Communications, 4(3), fcac119. (doi: 10.1093/braincomms/fcac119) (PMID:35651593) (PMCID:PMC9150072)
Mafra, D., Cardozo, L., Ribeiro-Alves, M., Bergman, P., Shiels, P. G. and Stenvinkel, P. (2022) Short Report: Choline plasma levels are related to Nrf2 transcriptional expression in chronic kidney disease? Clinical Nutrition ESPEN, 50, pp. 318-321. (doi: 10.1016/j.clnesp.2022.06.008) (PMID:35871941)
Mafra, D. et al. (2022) Archaea from the gut microbiota of humans: Could be linked to chronic diseases? Anaerobe, 77, 102629. (doi: 10.1016/j.anaerobe.2022.102629) (PMID:35985606)
Mahindra, A. et al. (2022) Investigating the structure–activity relationship of 1,2,4-triazine G-protein-coupled receptor 84 (GPR84) antagonists. Journal of Medicinal Chemistry, 65(16), pp. 11270-11290. (doi: 10.1021/acs.jmedchem.2c00804) (PMID:35948061) (PMCID:PMC9421653)
Main, A. and Fuller, W. (2022) Protein S‐palmitoylation: advances and challenges in studying a therapeutically important lipid modification. FEBS Journal, 289(4), pp. 861-882. (doi: 10.1111/febs.15781) (PMID:33624421)
Marsango, S., Barki, N., Jenkins, L. , Tobin, A. B. and Milligan, G. (2022) Therapeutic validation of an orphan G protein-coupled receptor: the case of GPR84. British Journal of Pharmacology, 179(14), pp. 3529-3541. (doi: 10.1111/bph.15248) (PMID:32869860) (PMCID:PMC9361006)
Marsango, S. et al. (2022) The M1 muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes. Proceedings of the National Academy of Sciences of the United States of America, 119(24), e220110311. (doi: 10.1073/pnas.2201103119) (PMID:35671422) (PMCID:PMC9214538)
Marsango, S. et al. (2022) Selective phosphorylation of threonine residues defines GPR84-arrestin interactions of biased ligands. Journal of Biological Chemistry, 298(5), 101932. (doi: 10.1016/j.jbc.2022.101932) (PMID:35427647) (PMCID:PMC9118924)
Martínez Corrales, G., Li, M., Svermova, T., Goncalves, A., Voicu, D., Dobson, A. J. , Southall, T. D. and Alic, N. (2022) Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodelling and Xbp1. Nature Aging, 2(12), pp. 1176-1190. (doi: 10.1038/s43587-022-00312-x) (PMID:37118537)
McAllister, B. et al. (2022) Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset. Nature Neuroscience, 25(4), pp. 446-457. (doi: 10.1038/s41593-022-01033-5) (PMID:35379994)
McGonigal, R. , Campbell, C. I., Barrie, J. A., Yao, D., Cunningham, M. E. , Crawford, C. L., Rinaldi, S., Rowan, E. G. and Willison, H. J. (2022) Schwann cell nodal membrane disruption triggers bystander axonal degeneration in a Guillain-Barré syndrome mouse model. Journal of Clinical Investigation, 132(14), e158524. (doi: 10.1172/JCI158524) (PMID:35671105) (PMCID:PMC9282931)
McInerny, C. J. , Crochet, P.‐A., Dudley, S. P. and on behalf of BOURC & AERC, (2022) Assessing vagrants from translocated populations and defining self-sustaining populations of non-native, naturalized and translocated avian species. Ibis, 164(3), pp. 924-928. (doi: 10.1111/ibi.13067)
McInerny, C. J. , Musgrove, A. J., Gilroy, J. J., Dudley, S. P. and the British Ornithologists’ Union Records Committee (BOURC), (2022) The British list: a checklist of birds of Britain (10th edition). Ibis, 164(3), pp. 860-910. (doi: 10.1111/ibi.13065)
Miguel-Romero, L., Alqasmi, M., Bacarizo, J., Tan, J. A., Cogdell, R. J. , Chen, J., Byron, O. , Christie, G. E., Marina, A. and Penadés, J. R. (2022) Non-canonical Staphylococcus aureus pathogenicity island repression. Nucleic Acids Research, 50(19), pp. 11109-11127. (doi: 10.1093/nar/gkac855) (PMID:36200825) (PMCID:PMC9638917)
Nakasone, M. A., Majorek, K. A., Gabrielsen, M. , Sibbet, G. J., Smith, B. O. and Huang, D. T. (2022) Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension. Nature Chemical Biology, 18, pp. 422-431. (doi: 10.1038/s41589-021-00952-x) (PMID:35027744) (PMCID:PMC8964413)
Naqvi, S., He, Q., Trusch, F., Qiu, H., Pham, J., Sun, Q., Christie, J. M. , Gilroy, E. M. and Birch, P. R.J. (2022) Blue‐light receptor phototropin 1 suppresses immunity to promote Phytophthora infestans infection. New Phytologist, 233(5), pp. 2282-2293. (doi: 10.1111/nph.17929) (PMID:34923631)
Neckebroeck, A., Kelly, S. M. , Smith, B. O. and Clark, J. S. (2022) Synthesis of the prototypical cyclopropyl dipeptide mimic and evaluation of its turn-inducing capability. Journal of Organic Chemistry, 87(1), pp. 258-270. (doi: 10.1021/acs.joc.1c02344) (PMID:34913698)
Oka, O. B. V. , Pierre, A. S., Pringle, M. A. , Tungkum, W., Cao, Z., Fleming, B. and Bulleid, N. J. (2022) Activation of the UPR sensor ATF6α is regulated by its redox-dependent dimerization and ER retention by ERp18. Proceedings of the National Academy of Sciences of the United States of America, 119(12), e2122657119. (doi: 10.1073/pnas.2122657119) (PMID:35286189) (PMCID:PMC8944254)
Oliwa, A., Hocking, C., Hamilton, M. J., Mclean, J. , Cumming, S., Ballantyne, B., Jampana, R., Longman, C., Monckton, D. G. and Farrugia, M. E. (2022) Masseter muscle volume as a disease marker in adult-onset myotonic dystrophy type 1. Neuromuscular Disorders, 32(11-12), pp. 893-902. (doi: 10.1016/j.nmd.2022.09.005) (PMID:36207221)
Osakunor, D. N.M., Ishida, K., Lamanna, O. K., Rossi, M., Dwomoh, L. and Hsieh, M. H. (2022) Host tissue proteomics reveal insights into the molecular basis of Schistosoma haematobium-induced bladder pathology. PLoS Neglected Tropical Diseases, 16(2), e0010176. (doi: 10.1371/journal.pntd.0010176) (PMID:35167594) (PMCID:PMC8846513)
Patitaki, E., Schivre, G., Zioutopoulou, A., Perrella, G., Bourbousse, C., Barneche, F. and Kaiserli, E. (2022) Light, chromatin, action: nuclear events regulating light signaling in Arabidopsis. New Phytologist, 236(2), pp. 333-349. (doi: 10.1111/nph.18424) (PMID:35949052) (PMCID:PMC9826491)
Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biomaterials to engineer hematopoietic stem cell niches. Advanced Healthcare Materials, 11(20), 2200964. (doi: 10.1002/adhm.202200964) (PMID:35933595)
Phillips, M. A. et al. (2022) Microscope-Cockpit: Python-based bespoke microscopy for bio-medical science. Wellcome Open Research, 6, 76. (doi: 10.12688/wellcomeopenres.16610.1) (PMID:37283605) (PMCID:PMC10240544)
Qian, P. et al. (2022) Cryo-EM structures of light-harvesting 2 complexes from Rhodopseudomonas palustris reveal the molecular origin of absorption tuning. Proceedings of the National Academy of Sciences of the United States of America, 117(43), e221010911. (doi: 10.1073/pnas.2210109119) (PMID:36251992) (PMCID:PMC9618040)
Rennie, M. L. , Arkinson, C., Chaugule, V. K. and Walden, H. (2022) Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Science Advances, 8(39), eabq6353. (doi: 10.1126/sciadv.abq6353) (PMID:36170365) (PMCID:PMC9519042)
Ronald, J. , Su, C., Wang, L. and Davis, S. J. (2022) Cellular localization of Arabidopsis EARLY FLOWERING3 is responsive to light quality. Plant Physiology, 190(2), pp. 1024-1036. (doi: 10.1093/plphys/kiac072) (PMID:35191492) (PMCID:PMC9516731)
Ryan, S. M. et al. (2022) Novel antiinflammatory biologics shaped by parasite–host coevolution. Proceedings of the National Academy of Sciences of the United States of America, 119(36), e220279511. (doi: 10.1073/pnas.2202795119) (PMID:36037362)
Seale, M. et al. (2022) Environmental morphing enables informed dispersal of the dandelion diaspore. eLife, 11, e81962. (doi: 10.7554/eLife.81962) (PMID:36445222) (PMCID:PMC9797189)
Tank, R., Ward, J. , Flegal, K. E. , Smith, D. J. , Bailey, M. E.S. , Cavanagh, J. and Lyall, D. M. (2022) Association between polygenic risk for Alzheimer’s disease, brain structure and cognitive abilities in UK Biobank. Neuropsychopharmacology, 47(2), pp. 564-569. (doi: 10.1038/s41386-021-01190-4) (PMID:34621014) (PMCID:PMC8674313)
Taylor, A. S. et al. (2022) Repeat Detector: versatile sizing of expanded tandem repeats and identification of interrupted alleles from targeted DNA sequencing. NAR Genomics and Bioinformatics, 4(4), lqac089. (doi: 10.1093/nargab/lqac089) (PMID:36478959) (PMCID:PMC9719798)
Teige, M., Jones, M. and Toledo-Ortiz, G. (2022) Plant organellar signalling—back and forth and intertwined with cellular signalling. Journal of Experimental Botany, 73(21), pp. 7103-7104. (doi: 10.1093/jxb/erac383) (PMID:36402134) (PMCID:PMC9675588)
Thomson, S. E. , Ng, N. Y.B., Riehle, M. O. , Kingham, P. J., Dahlin, L. B., Wiberg, M. and Hart, A. M. (2022) Bioengineered nerve conduits and wraps for peripheral nerve repair of the upper limb. Cochrane Database of Systematic Reviews, 2022(12), CD012574. (doi: 10.1002/14651858.CD012574.pub2) (PMID:36477774)
Tibbo, A. J. et al. (2022) Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins. Journal of Molecular and Cellular Cardiology, 165, pp. 86-102. (doi: 10.1016/j.yjmcc.2022.01.001) (PMID:34999055) (PMCID:PMC8986152)
Torres Cabán, C. C., Yang, M., Lai, C., Yang, L., Subach, F. V., Smith, B. O. , Piatkevich, K. D. and Boyden, E. S. (2022) Tuning the sensitivity of genetically encoded fluorescent potassium indicators through structure-guided and genome mining strategies. ACS Sensors, 7(5), pp. 1336-1346. (doi: 10.1021/acssensors.1c02201) (PMID:35427452) (PMCID:PMC9150168)
van der Plas, E., Long, J. D., Koscik, T. R., Magnotta, V., Monckton, D. G. , Cumming, S. A., Gottschalk, A. C., Hefti, M., Gutmann, L. and Nopoulos, P. C. (2022) Blood-based markers of neuronal injury in adult-onset myotonic dystrophy type 1. Frontiers in Neurology, 12, 791065. (doi: 10.3389/fneur.2021.791065) (PMID:35126292) (PMCID:PMC8810511)
Wang, Y., Karnik, R. , Garcia-Mata, C. and Hu, H. (2022) Editorial: transport and membrane traffic in stomatal biology. Frontiers in Plant Science, 13, 898128. (doi: 10.3389/fpls.2022.898128) (PMID:35712596) (PMCID:PMC9197599)
Weinhofer, I. et al. (2022) Peroxisomal very long-chain fatty acid transport is targeted by herpesviruses and the antiviral host response. Communications Biology, 5, 944. (doi: 10.1038/s42003-022-03867-y) (PMID:36085307) (PMCID:PMC9462615)
Wiejak, J., Luchowska-Stańska, U., Wang, P., Zhou, J., Maffia, P. , Morgan, D., Barker, G. and Yarwood, S. J. (2022) Protein interaction, cytotoxic, transcriptomic and proteomic responses to structurally distinct EPAC1 activators in HUVECs. Scientific Reports, 12, 16505. (doi: 10.1038/s41598-022-20607-8) (PMID:36198739) (PMCID:PMC9534843)
Winter, A. D., Tjahjono, E., Beltrán, L. L., Johnstone, I. L., Bulleid, N. J. and Page, A. P. (2022) Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents. BMC Biology, 20, 228. (doi: 10.1186/s12915-022-01415-y) (PMID:36209095) (PMCID:PMC9548181)
Wu, F., Finkelstein-Shapiro, D., Wang, M., Rosenkampff, I., Yartsev, A., Pascher, T., Nguyen- Phan, T. C., Cogdell, R. , Börjesson, K. and Pullerits, T. (2022) Optical cavity-mediated exciton dynamics in photosynthetic light harvesting 2 complexes. Nature Communications, 13, 6864. (doi: 10.1038/s41467-022-34613-x) (PMID:36369202) (PMCID:PMC9652305)
Xia, J., Pinto-Fernández, A., Damianou, A., Lee, J. Y., Kessler, B. M., Davis, I. , Elliott, P. and Ligoxygakis, P. (2022) Sex-specific deubiquitylation drives immune-related neurodegeneration in Drosophila. bioRxiv, (doi: 10.1101/2022.12.09.519782)
Xiao, Y., Donnelly, H. , Sprott, M. , Luo, J., Jayawarna, V., Lemgruber, L. , Tsimbouri, P. M. , Meek, R.M. D., Salmeron-Sanchez, M. and Dalby, M. J. (2022) Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis. Materials Today Bio, 16, 100367. (doi: 10.1016/j.mtbio.2022.100367) (PMID:35937570) (PMCID:PMC9352550)
Xiao, Y., McGuinness, C. A.S., Doherty-Boyd, W. S., Salmeron-Sanchez, M. , Donnelly, H. and Dalby, M. J. (2022) Current insights into the bone marrow niche: from biology in vivo to bioengineering ex vivo. Biomaterials, 286, 121568. (doi: 10.1016/j.biomaterials.2022.121568) (PMID:35580474)
Xu, J. et al. (2022) Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing. Proceedings of the National Academy of Sciences of the United States of America, 119(25), e220317911. (doi: 10.1073/pnas.2203179119) (PMID:35696569) (PMCID:PMC9231607)
Yu, J. et al. (2022) Dictamnine, a novel c-Met inhibitor, suppresses the proliferation of lung cancer cells by downregulating the PI3K/AKT/mTOR and MAPK signaling pathways. Biochemical Pharmacology, 195, 114864. (doi: 10.1016/j.bcp.2021.114864) (PMID:34861243)
Yukihira, N., Uragami, C., Horiuchi, K., Kosumi, D., Gardiner, A. T., Cogdell, R. J. and Hashimoto, H. (2022) Intramolecular charge-transfer enhances energy transfer efficiency in carotenoid-reconstituted light-harvesting 1 complex of purple photosynthetic bacteria. Communications Chemistry, 5, 135. (doi: 10.1038/s42004-022-00749-6) (PMID:36697849) (PMCID:PMC9814923)
Zahid, H., Lau, A. M., Kelly, S. M. , Karu, K., Gor, J., Perkins, S. J. and McDermott, L. C. (2022) Identification of diverse lipid‐binding modes in the groove of zinc α2 glycoprotein reveals its functional versatility. FEBS Journal, 289(7), pp. 1876-1896. (doi: 10.1111/febs.16293) (PMID:34817923)
Zambelloni, R., Beckham, K. S.H., Wu, H.-J., Elofsson, M., Marquez, R., Gabrielsen, M. and Roe, A. J. (2022) Crystal structures of WrbA, a spurious target of the salicylidene acylhydrazide inhibitors of type III secretion in Gram-negative pathogens, and verification of improved specificity of next-generation compounds. Microbiology, 168(7), 001211. (doi: 10.1099/mic.0.001211) (PMID:35829699)
Zhdanov, O. , Blatt, M. R. , Zare-Behtash, H. and Busse, A. (2022) Unidirectional versus bidirectional brushing: simulating wind influence on Arabidopsis thaliana. Quantitative Plant Biology, 3, e7. (doi: 10.1017/qpb.2021.14)
Zhou, J., Nguyen, T.‐H. , Hmidi, D., Luu, D.‐T., Sentenac, H. and Véry, A.‐A. (2022) The outward shaker channel OsK5.2 improves plant salt tolerance by contributing to control of both leaf transpiration and K+ secretion into xylem sap. Plant, Cell and Environment, 45(6), pp. 1734-1748. (doi: 10.1111/pce.14311) (PMID:35297056)
Zioutopoulou, A., Patitaki, E., O'Donnell, L. and Kaiserli, E. (2022) Low fluence ultraviolet-B promotes ultraviolet resistance 8-modulated flowering in Arabidopsis. Frontiers in Plant Science, 13, 840720. (doi: 10.3389/fpls.2022.840720) (PMID:35432431) (PMCID:PMC9009151)
Živković, D. et al. (2022) Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis. Proceedings of the National Academy of Sciences of the United States of America, 119(15), e2116826119. (doi: 10.1073/pnas.2116826119)
Book Sections
Knox, K. (2022) Super-resolution imaging of plasmodesmata using 3D structured illumination microscopy. In: Benitez-Alfonso, Y. and Heinlein, M. (eds.) Plasmodesmata: Methods and Protocols. Series: Methods in molecular biology (2457). Humana Press: New York, NY, pp. 143-148. ISBN 9781071621318 (doi: 10.1007/978-1-0716-2132-5_8)
Thu, N. B.A. , Amtmann, A. , Blatt, M. R. and Nguyen, T.-H. (2022) Stomata under salt stress—what can mechanistic modeling tell us? In: Shabala, S. (ed.) Stomata Regulation and Water Use Efficiency in Plants under Saline Soil Conditions. Series: Advances in botanical research (103). Academic Press: Amsterdam, pp. 139-162. ISBN 9780323912174 (doi: 10.1016/bs.abr.2022.02.012)
Conference or Workshop Item
Ciosi, M. , Young, R., Kwak, S. and Monckton, D. G. (2022) Longitudinal Analysis of Somatic Expansion of the HTT Repeat in Blood as a Potential Biomarker of Somatic Instability in Huntingon Disease. EHDN2022 Plenary Meeting - D: Wet biomarkers, Bologna, Italy, 16-18 September 2022. (doi: 10.1136/jnnp-2022-ehdn.57)
Ruiz de Sabando, A., Ciosi, M. , Galbete, A., Monckton, D. G. and Ramos-Arroyo, M. A. (2022) Somatic Mosaicism of the HTT Cag Repeat in Intermediate Allele Carriers with Neurocognitive Symptoms Compatible with Huntington Disease. EHDN2022 Plenary Meeting - A: Pathogenic mechanisms, Bologna, Italy, 16-18 September 2022. (doi: 10.1136/jnnp-2022-ehdn.1)
Wilson, J. (2022) Mouse Models of EBV Associated Disease, From Understanding Mechanism to Pre-clinical Model. International Symposium on EBV and associated diseases, Siena, Italy, 3-6 July 2022.
Yan, S. and Wilson, J. (2022) The Action of the Epstein-Barr Virus Oncogene LMP1 in Chronic Inflammation and Tumourigenesis. Microbiology Society JGV Roadshow, Glasgow, UK, 17 October 2022.
2021
Articles
Ahmed, S. F., Buetow, L., Gabrielsen, M. , Lilla, S., Sibbet, G. J., Sumpton, D., Zanivan, S. , Hedley, A., Clark, W. and Huang, D. T. (2021) E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis. Oncogene, 40(12), pp. 2149-2164. (doi: 10.1038/s41388-021-01684-x) (PMID:33627783) (PMCID:PMC7994203)
Ahwazi, D. et al. (2021) Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965. Biochemical Journal, 478(15), pp. 2977-2997. (doi: 10.1042/BCJ20210284) (PMID:34259310)
Anoar, S., Woodling, N. S. and Niccoli, T. (2021) Mitochondria dysfunction in frontotemporal dementia/amyotrophic lateral sclerosis: lessons from drosophila models. Frontiers in Neuroscience, 15, 786076. (doi: 10.3389/fnins.2021.786076) (PMID:34899176) (PMCID:PMC8652125)
Antoniou-Kourounioti, R. L. , Zhao, Y., Dean, C. and Howard, M. (2021) Feeling every bit of winter - distributed temperature sensitivity in vernalization. Frontiers in Plant Science, 12, 628726. (doi: 10.3389/fpls.2021.628726) (PMID:33584778) (PMCID:PMC7873433)
Bach, L. L. and Smith, B. (2021) Within and between day variability in coral reef fish assemblages: implications for fish community surveys. Journal of Applied Ichthyology, 37(6), pp. 847-856. (doi: 10.1111/jai.14267)
Baena, G. , Feria, A. B., Hernández-Huertas, L., Gandullo, J., Echevarría, C., Monreal, J. A. and García-Mauriño, S. (2021) Genetic and pharmacological inhibition of autophagy increases the monoubiquitination of non-photosynthetic phosphopyruvate carboxylase. Plants, 10(1), 12. (doi: 10.3390/plants10010012) (PMID:33374865) (PMCID:PMC7823769)
Barcelona Estaje, E., Dalby, M. J. , Cantini, M. and Salmeron-Sanchez, M. (2021) You talking to me? Cadherin and integrin crosstalk in biomaterials design. Advanced Healthcare Materials, 10(6), 2002048. (doi: 10.1002/adhm.202002048) (PMID:33586353)
Blatt, M. (2021) Ae fond fareweel. Plant Physiology, 187(4), pp. 2341-2343. (doi: 10.1093/plphys/kiab467) (PMID:34890468) (PMCID:PMC8644277)
Boleij, A. et al. (2021) G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis. Communications Biology, 4, 585. (doi: 10.1038/s42003-021-02014-3) (PMID:33990686) (PMCID:PMC8121840)
Bolognini, D., Dedeo, D. and Milligan, G. (2021) Metabolic and inflammatory functions of short-chain fatty acid receptors. Current Opinion in Endocrine and Metabolic Research, 16, pp. 1-9. (doi: 10.1016/j.coemr.2020.06.005) (PMID:32835130) (PMCID:PMC7332907)
Bolukbasi, E. et al. (2021) Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system. Proceedings of the National Academy of Sciences of the United States of America, 118(8), e201149111. (doi: 10.1073/pnas.2011491118) (PMID:33593901) (PMCID:PMC7923679)
Bonfini, A., Dobson, A. J. , Duneau, D., Revah, J., Liu, X., Houtz, P. and Buchon, N. (2021) Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size. eLife, 10, e64125. (doi: 10.7554/elife.64125) (PMID:34553686) (PMCID:PMC8528489)
Borrego-González, S., Dalby, M. J. and Díaz-Cuenca, A. (2021) Nanofibrous gelatin-based biomaterial with improved biomimicry using D-periodic self-assembled atelocollagen. Biomimetics, 6(1), 20. (doi: 10.3390/biomimetics6010020) (PMID:33803778) (PMCID:PMC8006151)
Bourgognon, J.-M. , Spiers, J. G., Robinson, S. W., Scheiblich, H., Glynn, P., Ortori, C., Bradley, S. J. , Tobin, A. B. and Steinert, J. R. (2021) Inhibition of neuroinflammatory nitric oxide signaling suppresses glycation and prevents neuronal dysfunction in mouse prion disease. Proceedings of the National Academy of Sciences of the United States of America, 118(10), e200957911. (doi: 10.1073/pnas.2009579118) (PMID:33653950)
Bowman, P. R.T., Smith, G. L. and Gould, G. W. (2021) Run for your life: can exercise be used to effectively target GLUT4 in diabetic cardiac disease? PeerJ, 9, e11485. (doi: 10.7717/peerj.11485) (PMID:34113491) (PMCID:PMC8162245)
Brown, A. J.H. et al. (2021) From structure to clinic: design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer’s disease. Cell, 184(24), 5886-5901.e22. (doi: 10.1016/j.cell.2021.11.001) (PMID:34822784)
Buist, H. K. et al. (2021) Identification and characterization of an affimer affinity reagent for the detection of the cAMP sensor, EPAC1. Cells, 10(9), 2307. (doi: 10.3390/cells10092307)
Burger, W. A. C. et al. (2021) Identification of a novel allosteric site at the M5 muscarinic acetylcholine receptor. ACS Chemical Neuroscience, 12(16), pp. 3112-3123. (doi: 10.1021/acschemneuro.1c00383) (PMID:34351123)
Castejón-Vega, B. , Battino, M., Quiles, J. L., Bullon, B., Cordero, M. D. and Bullón, P. (2021) Potential role of the mitochondria for the dermatological treatment of Papillon-Lefèvre. Antioxidants, 10(1), 95. (doi: 10.3390/antiox10010095) (PMID:33445524) (PMCID:PMC7827181)
Castejón-Vega, B. et al. (2021) L-arginine ameliorates defective autophagy in GM2 gangliosidoses by mTOR modulation. Cells, 10(11), 3122. (doi: 10.3390/cells10113122)
Channumsin, M., Ciosi, M. , Masiga, D., Auty, H. , Turner, C. M., Kilbride, E. and Mable, B. K. (2021) Blood meal analysis of tsetse flies (Glossina pallidipes: Glossinidae) reveals higher host fidelity on wild compared with domestic hosts. Wellcome Open Research, 6, 213. (doi: 10.12688/wellcomeopenres.16978.1) (PMCID:PMC8513123)
Christie, J. M. and Zurbriggen, M. D. (2021) Optogenetics in plants. New Phytologist, 229(6), pp. 3108-3115. (doi: 10.1111/nph.17008) (PMID:33064858)
Ciosi, M. et al. (2021) Approaches to sequence the HTT CAG repeat expansion and quantify repeat length variation. Journal of Huntington's Disease, 10(1), pp. 53-74. (doi: 10.3233/jhd-200433) (PMID:33579864) (PMCID:PMC7990409)
Clayton, S. A. et al. (2021) Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48. Science Advances, 7(50), eabl5182. (doi: 10.1126/sciadv.abl5182) (PMID:34878835)
Cumming, S. A., Oliwa, A., Stevens, G., Ballantyne, B., Mann, C., Razvi, S., Longman, C., Monckton, D. G. and Farrugia, M. E. (2021) A DM1 patient with CCG variant repeats: reaching the diagnosis. Neuromuscular Disorders, 31(3), pp. 232-238. (doi: 10.1016/j.nmd.2020.12.005) (PMID:33546847)
Čunátová, K., Reguera, D. P., Vrbacký, M., Fernández-Vizarra, E., Ding, S., Fearnley, I., Zeviani, M., Houštěk, J., Mráček, T. and Pecina, P. (2021) Loss of COX4I1 leads to combined respiratory chain deficiency and impaired mitochondrial protein synthesis. Cells, 10(2), 369. (doi: 10.3390/cells10020369) (PMID:33578848) (PMCID:PMC7916595)
Diamantopoulou, C., Christoforou, E., Dominoni, D. M. , Kaiserli, E. , Czyzewski, J., Mirzai, N. and Spatharis, S. (2021) Wavelength-dependent effects of artificial light at night on phytoplankton growth and community structure. Proceedings of the Royal Society of London Series B: Biological Sciences, 288(1953), 20210525. (doi: 10.1098/rspb.2021.0525) (PMID:34157871)
Dickson-Murray, E., Nedara, K., Modjtahedi, N. and Tokatlidis, K. (2021) The Mia40/CHCHD4 oxidative folding system: Redox regulation and signaling in the mitochondrial intermembrane space. Antioxidants, 10(4), 592. (doi: 10.3390/antiox10040592) (PMID:33921425) (PMCID:PMC8069373)
Dimogkioka, A.-R., Lees, J., Tokatlidis, K. and Lacko, E. (2021) Protein import in mitochondria biogenesis: Guided by targeting signals and sustained by dedicated chaperones. RSC Advances, 11(51), pp. 32476-32493. (doi: 10.1039/D1RA04497D)
Dobre, O. et al. (2021) A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors – neural growth and osteogenesis. Advanced Functional Materials, 31(21), 2010225. (doi: 10.1002/adfm.202010225)
Dow, J. A.T. , Krause, S. A. and Herzyk, P. (2021) Updates on ion and water transport by the Malpighian tubule. Current Opinion in Insect Science, 47, pp. 31-37. (doi: 10.1016/j.cois.2021.02.018) (PMID:33705976)
Eaglesfield, R., Madsen, M. A., Sanyal, S., Reboud, J. and Amtmann, A. (2021) Co-translational recruitment of ribosomes in minimal protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis. iScience, 24(5), 102429. (doi: 10.1016/j.isci.2021.102429) (PMID:33997704) (PMCID:PMC8102411)
Edwards, R., Eaglesfield, R. and Tokatlidis, K. (2021) The mitochondrial intermembrane space: the most constricted mitochondrial sub-compartment with the largest variety of protein import pathways. Open Biology, 11(3), 210002. (doi: 10.1098/rsob.210002) (PMID:33715390) (PMCID:PMC8061763)
Fernandez-Vizarra, E. and Zeviani, M. (2021) Mitochondrial disorders of the OXPHOS system. FEBS Letters, 595(8), pp. 1062-1106. (doi: 10.1002/1873-3468.13995) (PMID:33159691)
Galović, V., Kebert, M., Popović, B. M., Kovačević, B., Vasić, V., Joseph, M. P. , Orlović, S. and Szabados, L. (2021) Biochemical and gene expression analyses in different poplar clones: the selection tools for afforestation of halomorphic environments. Forests, 12(5), 636. (doi: 10.3390/f12050636)
Gardiner, A. T., Naydenova, K., Castro-Hartmann, P., Nguyen-Phan, C. T., Russo, C. J., Sader, K., Hunter, C. N., Cogdell, R. J. and Qian, P. (2021) The 2.4 Å cryo-EM structure of a heptameric light-harvesting 2 complex reveals two carotenoid energy transfer pathways. Science Advances, 7(7), eabe4650. (doi: 10.1126/sciadv.abe4650) (PMID:33579696) (PMCID:PMC7880592)
Garner, S. J., Dalby, M. J. , Nobbs, A. H. and Barbour, M. E. (2021) A novel chlorhexidine-hexametaphosphate coating for titanium with antibiofilm efficacy and stem cell cytocompatibility. Journal of Materials Science: Materials in Medicine, 32(12), 139. (doi: 10.1007/s10856-021-06616-5)
Gavazzo, P., Viti, F., Donnelly, H. , Oliva, M. A. G., Salmeron-Sanchez, M. , Dalby, M. J. and Vassalli, M. (2021) Biophysical phenotyping of mesenchymal stem cells along the osteogenic differentiation pathway. Cell Biology and Toxicology, 37(6), pp. 915-933. (doi: 10.1007/s10565-020-09569-7) (PMID:33420657)
Geldon, S., Fernandez-Vizarra, E. and Tokatlidis, K. (2021) Redox-mediated regulation of mitochondrial biogenesis, dynamics and respiratory chain assembly in yeast and human cells. Frontiers in Cell and Developmental Biology, 9, 720656. (doi: 10.3389/fcell.2021.720656) (PMID:34557489) (PMCID:PMC8452992)
Gilroy, J., McInerny, C. , Dudley, S., Balmer, D., Batty, C., Crochet, P.-A., French, P., Lees, A., Musgrove, A. and Stoddart, A. (2021) British Ornithologists’ Union Records Committee (BOURC): 52nd Report (January 2021). Ibis, 163(1), pp. 305-308. (doi: 10.1111/ibi.12900)
Gök, C. , Main, A., Gao, X., Kerekes, Z., Plain, F., Kuo, C.-W., Robertson, A. D., Fraser, N. J. and Fuller, W. (2021) Insights into the molecular basis of the palmitoylation and depalmitoylation of NCX1. Cell Calcium, 97, 102408. (doi: 10.1016/j.ceca.2021.102408) (PMID:33873072)
Gomes-Pereira, M. and Monckton, D. G. (2021) Chronic exposure to cadmium and antioxidants does not affect the dynamics of expanded CAG•CTG trinucleotide repeats in a mouse cell culture system of unstable DNA. Frontiers in Cellular Neuroscience, 14, 606331. (doi: 10.3389/fncel.2020.606331) (PMID:33603644) (PMCID:PMC7884634)
Gundogdu, M., Tadayon, R., Salzano, G. , Shaw, G. S. and Walden, H. (2021) A mechanistic review of Parkin activation. Biochimica et Biophysica Acta. General Subjects, 1865(6), 129894. (doi: 10.1016/j.bbagen.2021.129894) (PMID:33753174)
Hajiali, H., Ouyang, L., Llopis-Hernandez, V. , Dobre, O. and Rose, F. R. A. J. (2021) Review of emerging nanotechnology in bone regeneration: progress, challenges, and perspectives. Nanoscale, 13(23), pp. 10266-10280. (doi: 10.1039/D1NR01371H) (PMID:34085085)
Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)
Hyde, K., Sultana, N., Tran, A. C., Bileckaja, N., Donald, C. L. , Kohl, A. , Stanton, R. J. and Strang, B. L. (2021) Limited replication of human cytomegalovirus in a trophoblast cell line. Journal of General Virology, 102(11), 001683. (doi: 10.1099/jgv.0.001683)
Jani, B. D. et al. (2021) Family history of diabetes and risk of SARS-COV-2 in UK Biobank: a prospective cohort study. Endocrinology, Diabetes and Metabolism, 4(4), e00283. (doi: 10.1002/edm2.283) (PMID:34505416) (PMCID:PMC8420405)
Jezek, M. et al. (2021) Guard cell endomembrane Ca2+-ATPases underpin a ‘carbon memory’ of photosynthetic assimilation that impacts on water-use efficiency. Nature Plants, 7(9), pp. 1301-1313. (doi: 10.1038/s41477-021-00966-2) (PMID:34326530)
Johnston, K. J.A. et al. (2021) Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 17(4), e1009428. (doi: 10.1371/journal.pgen.1009428) (PMID:33830993) (PMCID:PMC8031124)
Kakoulidou, I. et al. (2021) Epigenetics for crop improvement in times of global change. Biology, 10(8), 766. (doi: 10.3390/biology10080766)
Kamel, W. et al. (2021) Global analysis of protein-RNA interactions in SARS-CoV-2 infected cells reveals key regulators of infection. Molecular Cell, 81(13), 2851-2867.e7. (doi: 10.1016/j.molcel.2021.05.023) (PMID:34118193) (PMCID:PMC8142890)
Kennedy, J. W., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P. G., Reid, S., Young, P. S., Meek, D. R. M., Goodyear, C. S. and Dalby, M. J. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. Scientific Reports, 11, 22741. (doi: 10.1038/s41598-021-02139-9)
Kim, J., Nguyen-Phan, T. C., Gardiner, A. T., Cogdell, R. J. , Scholes, G. D. and Cho, M. (2021) Low-frequency vibronic mixing modulates the excitation energy flow in bacterial light-harvesting complex II. Journal of Physical Chemistry Letters, 12(27), pp. 6292-6298. (doi: 10.1021/acs.jpclett.1c01782) (PMID:34213343)
Klejchova, M. , Silva-Alvim, F. A.L., Blatt, M. R. and Alvim, J. C. (2021) Membrane voltage as a dynamic platform for spatio-temporal signalling, physiological and developmental regulation. Plant Physiology, 185(4), pp. 1523-1541. (doi: 10.1093/plphys/kiab032) (PMID:33598675)
Klionsky, D. J. et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), pp. 1-382. (doi: 10.1080/15548627.2020.1797280) (PMID:33634751) (PMCID:PMC7996087)
Kopietz, F., Alshuweishi, Y., Bijland, S., Alghamdi, F., Degerman, E., Sakamoto, K., Salt, I. P. and Göransson, O. (2021) A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner. Biochemical Journal, 478(3), pp. 633-646. (doi: 10.1042/BCJ20200659) (PMID:33493298)
Koscik, T. R., van der Plas, E., Gutmann, L., Cumming, S. A., Monckton, D. G. , Magnotta, V., Shields, R. K. and Nopoulos, P. C. (2021) White matter microstructure relates to motor outcomes in myotonic dystrophy type 1 independently of disease duration and genetic burden. Scientific Reports, 11, 4886. (doi: 10.1038/s41598-021-84520-2) (PMID:33649422) (PMCID:PMC7921687)
Koyama, T., Terhzaz, S. , Naseem, M. T., Nagy, S., Rewitz, K., Dow, J. A.T. , Davies, S. A. and Halberg, K. V. (2021) A nutrient-responsive hormonal circuit mediates an inter-tissue program regulating metabolic homeostasis in adult Drosophila. Nature Communications, 12, 5178. (doi: 10.1038/s41467-021-25445-2) (PMID:34462441) (PMCID:PMC8405823)
Lefoulon, C. (2021) The bare necessities of plant K+ channel regulation. Plant Physiology, 187(4), pp. 2092-2109. (doi: 10.1093/plphys/kiab266) (PMID:34618033)
Lin, L.-C., Quon, T., Engberg, S., Mackenzie, A. E., Tobin, A. B. and Milligan, G. (2021) G protein-coupled receptor GPR35 suppresses lipid accumulation in hepatocytes. ACS Pharmacology and Translational Science, 4(6), pp. 1835-1848. (doi: 10.1021/acsptsci.1c00224) (PMID:34927014)
Madsen, M. A., Hamilton, G., Herzyk, P. and Amtmann, A. (2021) Environmental regulation of PndbA600, an auto-inducible promoter for two-stage industrial biotechnology in cyanobacteria. Frontiers in Bioengineering and Biotechnology, 8, 619055. (doi: 10.3389/fbioe.2020.619055) (PMID:33542914) (PMCID:PMC7853294)
Mahindra, A. et al. (2021) Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction. PLoS ONE, 16(11), e0260283. (doi: 10.1371/journal.pone.0260283) (PMID:34793553) (PMCID:PMC8601423)
Main, K. H.S., Provan, J., Haynes, P. J., Wells, G., Hartley, J. A. and Pyne, A. L.B. (2021) Atomic force microscopy—A tool for structural and translational DNA research. APL Bioengineering, 5(3), 031504. (doi: 10.1063/5.0054294) (PMID:34286171) (PMCID:PMC8272649)
McGonigal, R. , Barrie, J. A., Yao, D., Black, L. E. , McLaughlin, M. and Willison, H. J. (2021) Neuronally expressed a-series gangliosides are sufficient to prevent the lethal age-dependent phenotype in GM3-only expressing mice. Journal of Neurochemistry, 158(2), pp. 217-232. (doi: 10.1111/jnc.15365) (PMID:33864399)
McLuskey, K., Wandy, J. , Vincent, I. , Van Der Hooft, J. J.J. , Rogers, S. , Burgess, K. and Daly, R. (2021) Ranking metabolite sets by their activity levels. Metabolites, 11(2), 103. (doi: 10.3390/metabo11020103) (PMID:33670102) (PMCID:PMC7916825)
Miller, J. N., Kruger, A., Moser, D. J., Gutmann, L., van der Plas, E., Koscik, T. R., Cumming, S. A., Monckton, D. G. and Nopoulos, P. C. (2021) Cognitive deficits, apathy, and hypersomnolence represent the core brain symptoms of adult-onset myotonic dystrophy type 1. Frontiers in Neurology, 12, 700796. (doi: 10.3389/fneur.2021.700796) (PMID:34276551) (PMCID:PMC8280288)
Milligan, G. , Barki, N. and Tobin, A. (2021) Chemogenetic approaches to explore the functions of Free Fatty Acid Receptor 2. Trends in Pharmacological Sciences, 42(3), pp. 191-202. (doi: 10.1016/j.tips.2020.12.003) (PMID:33495026)
Milligan, G. et al. (2021) Discovery and characterization of novel antagonists of the proinflammatory orphan receptor GPR84. ACS Pharmacology and Translational Science, 4(5), pp. 1598-1613. (doi: 10.1021/acsptsci.1c00151) (PMID:34661077) (PMCID:PMC8506611)
Mitchell, J., Smith, C. S., Titlow, J., Otto, N., van Velde, P., Booth, M., Davis, I. and Waddell, S. (2021) Selective dendritic localization of mRNA in Drosophila mushroom body output neurons. eLife, 10, e62770. (doi: 10.7554/eLife.62770) (PMID:33724180) (PMCID:PMC8004107)
Mladenov, V. et al. (2021) Deciphering the epigenetic alphabet involved in transgenerational stress memory in crops. International Journal of Molecular Sciences, 22(13), 7118. (doi: 10.3390/ijms22137118)
Mok, S. et al. (2021) Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival. Nature Communications, 12, 530. (doi: 10.1038/s41467-020-20805-w) (PMID:33483501) (PMCID:PMC7822823)
Moliner, F., Knox, K. , Gordon, D., Lee, M., Tipping, W. J., Geddis, A., Reinders, A., Ward, J. M., Oparka, K. and Vendrell, M. (2021) A palette of minimally tagged sucrose analogues for real‐time Raman imaging of intracellular plant metabolism. Angewandte Chemie (International Edition), 60(14), pp. 7637-7642. (doi: 10.1002/anie.202016802) (PMID:33491852) (PMCID:PMC8048481)
Morgan, D. C. et al. (2021) Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalisation. Peptide Science, 113(4), e24217. (doi: 10.1002/pep2.24217) (PMID:33615115) (PMCID:PMC7883042)
Morris, E. P. and da Fonseca, P. C.A. (2021) How to build a proteasome. Nature Structural and Molecular Biology, 28(5), pp. 409-410. (doi: 10.1038/s41594-021-00592-8)
Navarro-Pando, J. M. et al. (2021) Inhibition of the NLRP3 inflammasome prevents ovarian aging. Science Advances, 7(1), eabc7409. (doi: 10.1126/sciadv.abc7409) (PMID:33523841) (PMCID:PMC7775749)
Navas, P. and Sanz, A. (2021) Editorial: "Mitochondrial Coenzyme Q Homeostasis: signalling, respiratory chain stability and diseases.". Free Radical Biology and Medicine, 169, pp. 12-13. (doi: 10.1016/j.freeradbiomed.2021.04.005) (PMID:33845159)
Nimmo, H. G. and Laird, J. (2021) Arabidopsis thaliana PRR7 provides circadian input to the CCA1 promoter in shoots but not roots. Frontiers in Plant Science, 12, 750367. (doi: 10.3389/fpls.2021.750367) (PMCID:PMC8559795)
Palmer, T. M. and Salt, I. P. (2021) Nutrient regulation of inflammatory signalling in obesity and vascular disease. Clinical Science, 135(13), pp. 1563-1590. (doi: 10.1042/CS20190768) (PMID:34231841)
Pokhilko, A. et al. (2021) Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease. Journal of Cerebral Blood Flow and Metabolism, 41(9), pp. 2423-2438. (doi: 10.1177/0271678X211004307) (PMID:33730931)
Prabhakar, A. T. et al. (2021) CK2 phosphorylation of human papillomavirus 16 E2 on serine 23 promotes interaction with TopBP1 and is critical for E2 interaction with mitotic chromatin and the viral life cycle. mBio, 12, e01163-21. (doi: 10.1128/mbio.01163-21) (PMID:34544280) (PMCID:PMC8546539)
Reichert, P. and Caudron, F. (2021) Mnemons and the memorization of past signaling events. Current Opinion in Cell Biology, 69, pp. 127-135. (doi: 10.1016/j.ceb.2021.01.005) (PMID:33618243)
Rendón-Anaya, M. et al. (2021) Adaptive introgression facilitates adaptation to high latitudes in European aspen (Populus tremula L.). Molecular Biology and Evolution, 38(11), pp. 5034-5050. (doi: 10.1093/molbev/msab229) (PMID:34329481) (PMCID:PMC8557470)
Rennie, M. L. , Arkinson, C., Chaugule, V. K. , Toth, R. and Walden, H. (2021) Structural basis of FANCD2 deubiquitination by USP1-UAF1. Nature Structural and Molecular Biology, 28(4), pp. 356-364. (doi: 10.1038/s41594-021-00576-8) (PMID:33795880)
Rezig, I. M., Yaduma, W. G., Gould, G. W. and McInerny, C. J. (2021) Anillin/Mid1p interacts with the ESCRT-associated protein Vps4p and mitotic kinases to regulate cytokinesis in fission yeast. Cell Cycle, 20(18), pp. 1845-1860. (doi: 10.1080/15384101.2021.1962637) (PMID:34382912) (PMCID:PMC8525990)
Rodrigo-Navarro, A. , Sankaran, S., Dalby, M. J. , del Campo, A. and Salmeron-Sanchez, M. (2021) Engineered living biomaterials. Nature Reviews Materials, 6(12), pp. 1175-1190. (doi: 10.1038/s41578-021-00350-8)
Rolczynski, B. S. et al. (2021) Time-domain line-shape analysis from 2D spectroscopy to precisely determine Hamiltonian parameters for a photosynthetic complex. Journal of Physical Chemistry B, 125(11), pp. 2812-2820. (doi: 10.1021/acs.jpcb.0c08012) (PMID:33728918)
Ronald, J. , Wilkinson, A. J. and Davis, S. J. (2021) EARLY FLOWERING3 sub-nuclear localization responds to changes in ambient temperature. Plant Physiology, 187(4), pp. 2352-2355. (doi: 10.1093/plphys/kiab423) (PMID:34618097) (PMCID:PMC8644450)
Salt, I. P. , Nunes, J. R.C. and Fullerton, M. D. (2021) Metformin again? Atheroprotection mediated by macrophage AMPK and ATF1. Cardiovascular Research, 117(5), pp. 1233-1234. (doi: 10.1093/cvr/cvab065) (PMID:33681999)
Sarrigiannidis, S. O., Rey, J. M., Dobre, O. , Gonzalez Garcia, C., Dalby, M. J. and Salmeron-Sanchez, M. (2021) A tough act to follow: collagen hydrogel modifications to improve mechanical and growth factor loading capabilities. Materials Today Bio, 10, 100098. (doi: 10.1016/j.mtbio.2021.100098) (PMID:33763641) (PMCID:PMC7973388)
Scammells, P. J. et al. (2021) Development of novel 4‐arylpyridin‐2‐one and 6‐arylpyrimidin‐4‐one positive allosteric modulators of the M1 muscarinic acetylcholine receptor. ChemMedChem, 16(1), pp. 216-233. (doi: 10.1002/cmdc.202000540) (PMID:32851779)
Scarpa, M. et al. (2021) Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease. Proceedings of the National Academy of Sciences of the United States of America, 118(50), e2107389118. (doi: 10.1073/pnas.2107389118) (PMID:34893539) (PMCID:PMC8685681)
Schofield, C. L., Rodrigo-Navarro, A. , Dalby, M. J. , Van Agtmael, T. and Salmeron-Sanchez, M. (2021) Biochemical– and biophysical–induced barriergenesis in the blood brain barrier: a review of barriergenic factors for use in in vitro models. Advanced NanoBiomed Research, 1(5), 2000068. (doi: 10.1002/anbr.202000068)
Schultz, V. et al. (2021) Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. Viruses, 13(1), 91. (doi: 10.3390/v13010091) (PMID:33440758) (PMCID:PMC7827345)
Scialo, F. and Sanz, A. (2021) Coenzyme Q redox signalling and longevity. Free Radical Biology and Medicine, 164, pp. 187-205. (doi: 10.1016/j.freeradbiomed.2021.01.018) (PMID:33450379)
Simon, G., Busch, C., Andrade, M. A. B., Reboud, J. , Cooper, J. M. , Desmulliez, M. P. Y., Riehle, M. O. and Bernassau, A. L. (2021) Bandpass sorting of heterogeneous cells using a single surface acoustic wave transducer pair. Biomicrofluidics, 15(1), 014105. (doi: 10.1063/5.0040181) (PMID:33537112) (PMCID:PMC7843154)
Sloan, W. T. , Nnaji, C. F., Lunn, M., Curtis, T. P., Colloms, S. D., Couto, J. M., Pinto, A. J., Connelly, S. and Rosser, S. J. (2021) Drift dynamics in microbial communities and the effective community size. Environmental Microbiology, 23(5), pp. 2473-2483. (doi: 10.1111/1462-2920.15453) (PMID:33684262)
Stevens, J., Jones, M. A. and Lawson, T. (2021) Diverse physiological and physical responses among wild, landrace and elite barley varieties point to novel breeding opportunities. Agronomy, 11(5), 921. (doi: 10.3390/agronomy11050921)
Strawbridge, R. J. et al. (2021) The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals. Scientific Reports, 11, 632. (doi: 10.1038/s41598-020-79964-x) (PMID:33436761) (PMCID:PMC7804422)
Sullivan, S. , Waksman, T., Paliogianni, D., Henderson, L., Lütkemeyer, M., Suetsugu, N. and Christie, J. M. (2021) Regulation of plant phototropic growth by NPH3/RPT2-like substrate phosphorylation and 14-3-3 binding. Nature Communications, 12, 6129. (doi: 10.1038/s41467-021-26333-5) (PMID:34675214) (PMCID:PMC8531357)
Susano Pinto, D. M., Phillips, M. A., Hall, N., Mateos-Langerak, J., Stoychev, D., Susano Pinto, T., Booth, M. J., Davis, I. and Dobbie, I. M. (2021) Python-Microscope – a new open-source Python library for the control of microscopes. Journal of Cell Science, 134(19), jcs258955. (doi: 10.1242/jcs.258955) (PMID:34448002) (PMCID:PMC8520730)
Thyrhaug, E., Schröter, M., Bukartė, E., Kühn, O., Cogdell, R. , Hauer, J. and Zigmantas, D. (2021) Intraband dynamics and exciton trapping in the LH2 complex of Rhodopseudomonas acidophila. Journal of Chemical Physics, 154(4), 045102. (doi: 10.1063/5.0033802) (PMID:33514092)
Tokatlidis, K. and Eaglesfield, R. (2021) Targeting and insertion of membrane proteins in mitochondria. Frontiers in Cell and Developmental Biology, 9, 803205. (doi: 10.3389/fcell.2021.803205) (PMID:35004695) (PMCID:PMC8740019)
van Beek, L., McClay, É., Patel, S., Schimpl, M., Spagnolo, L. and Maia de Oliveira, T. (2021) PARP power: a structural perspective on PARP1, PARP2, and PARP3 in DNA damage repair and nucleosome remodelling. International Journal of Molecular Sciences, 22(10), 5112. (doi: 10.3390/ijms22105112) (PMID:34066057) (PMCID:PMC8150716)
van der Plas, E., Koscik, T. R., Magnotta, V., Cumming, S. A., Monckton, D. , Gutmann, L. and Nopoulos, P. (2021) Neurocognitive features of motor premanifest individuals with myotonic dystrophy type 1. Neurology Genetics, 7(2), e577. (doi: 10.1212/NXG.0000000000000577) (PMID:33912661) (PMCID:PMC8075572)
van Lith, M., Pringle, M. A. , Fleming, B., Gaeta, G., Im, J., Gilmore, R. and Bulleid, N. J. (2021) A cytosolic reductase pathway is required for efficient N-glycosylation of an STT3B-dependent acceptor site. Journal of Cell Science, 134(22), jcs259340. (doi: 10.1242/jcs.259340) (PMID:34734627) (PMCID:PMC8645230)
Ward, R. J., Pediani, J. D. , Marsango, S., Jolly, R., Stoneman, M. R., Biener, G., Handel, T. M., Raicu, V. and Milligan, G. (2021) Chemokine receptor CXCR4 oligomerization is disrupted selectively by the antagonist ligand IT1t. Journal of Biological Chemistry, 296, 100139. (doi: 10.1074/jbc.RA120.016612) (PMID:33268380)
Wei, D., Charlton, L., Glidle, A., Qi, N., Dobson, P. S. , Dalby, M. J. , Fan, H. and Yin, H. (2021) Dynamically modulated core-shell microfibers to study the effect of depth sensing of matrix stiffness on stem cell fate. ACS Applied Materials and Interfaces, 13(32), pp. 37997-38006. (doi: 10.1021/acsami.1c06752) (PMID:34355561)
Wenninger, S. et al. (2021) Associations between variant repeat interruptions and clinical outcomes in myotonic dystrophy type 1. Neurology Genetics, 7(2), e572. (doi: 10.1212/NXG.0000000000000572) (PMID:33884298) (PMCID:PMC8054967)
Wickenhagen, A. et al. (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567), eabj3624. (doi: 10.1126/science.abj3624) (PMID:34581622) (PMCID:PMC7612834)
Wing, P. A.C. et al. (2021) Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells. Cell Reports, 35(3), 109020. (doi: 10.1016/j.celrep.2021.109020) (PMID:33852916) (PMCID:PMC8020087)
Zhang, B. , Xia, L. , Zhang, Y., Wang, H. and Karnik, R. (2021) Tri-SUS: a yeast split-ubiquitin assay to examine protein interactions governed by a third binding partner. Plant Physiology, 185(2), pp. 285-289. (doi: 10.1093/plphys/kiaa039) (PMID:33721898)
Zhao, Y., Zhu, P., Hepworth, J., Bloomer, R., Antoniou-Kourounioti, R. L. , Doughty, J., Heckmann, A., Xu, C., Yang, H. and Dean, C. (2021) Natural temperature fluctuations promote COOLAIR regulation of FLC. Genes and Development, 35(11-12), pp. 888-898. (doi: 10.1101/gad.348362.121) (PMID:33985972) (PMCID:PMC8168555)
Zhdanov, O. , Blatt, M. R. , Zare-Behtash, H. and Busse, A. (2021) Wind-evoked anemotropism affects the morphology and mechanical properties of Arabidopsis. Journal of Experimental Botany, 72(5), pp. 1906-1918. (doi: 10.1093/jxb/eraa541) (PMID:33206167)
Zioutopoulou, A., Patitaki, E., Xu, T. and Kaiserli, E. (2021) The epigenetic mechanisms underlying thermomorphogenesis and heat stress responses in Arabidopsis. Plants, 10(11), 2439. (doi: 10.3390/plants10112439)
Book Sections
Perrella, G., Zioutopoulou, A., Hamilton, A. and Kaiserli, E. (2021) Photobody detection using immunofluorescence and super-resolution imaging in Arabidopsis. In: Yin, R., Li, L. and Zuo, K. (eds.) Plant Photomorphogenesis: Methods and Protocols. Series: Methods in molecular biology (2297). Humana: New York, NY, pp. 7-19. ISBN 9781071613696 (doi: 10.1007/978-1-0716-1370-2_2)
Tzioutziou, N. A., James, A. B. , Guo, W., Calixto, C. P.G., Zhang, R., Nimmo, H. G. and Brown, J. W.S. (2021) Experimental design for time-series RNA-seq analysis of gene expression and alternative splicing. In: Staiger, D., Davis, S. and Davis, A. M. (eds.) Plant Circadian Networks: Methods and Protocols. Series: Methods in molecular biology (2398). Humana: New York, pp. 173-188. ISBN 9781071619117 (doi: 10.1007/978-1-0716-1912-4_14)
Veitch, N. and Donald, C. (2021) Improving student engagement in the virtual world of disease diagnostics. In: Tasler, N., O'Brien, R. and Spiers, A. (eds.) Being Creative in the Face of Diversity. Series: The #creativeHE Annual 2021., 1. The Creativity for Learning in Higher Education community, pp. 69-71. (doi: 10.25416/NTR.17709860.v1)
Conference or Workshop Item
Veitch, N. and Donald, C. (2021) Enhancing the student experience with a virtual reality disease diagnostics lab. ALT-ELESIG Scotland Meeting, Online, 26 November 2021.
2020
Articles
Alba, A., Jayawarna, V., Childs, P. G., Dalby, M. J. and Salmeron-Sanchez, M. (2020) Plasma polymerised nanoscale coatings of controlled thickness for efficient solid-phase presentation of growth factors. Materials Science and Engineering C: Materials for Biological Applications, 113, 110966. (doi: 10.1016/j.msec.2020.110966) (PMID:32487385)
Alghamdi, F., Alshuweishi, Y. and Salt, I. P. (2020) Regulation of nutrient uptake by AMP-activated protein kinase. Cellular Signalling, 76, 109807. (doi: 10.1016/j.cellsig.2020.109807) (PMID:33038517)
Anderson, R. et al. (2020) NLRP3 inflammasome inhibition by MCC950 in aged mice improves health via enhanced autophagy and PPARα activity. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 75(8), pp. 1457-1464. (doi: 10.1093/gerona/glz239) (PMID:31603987)
Arp, T. B., Kistner-Morris, J., Aji, V., Cogdell, R. J. , van Grondelle, R. and Gabor, N. M. (2020) Quieting a noisy antenna reproduces photosynthetic light-harvesting spectra. Science, 368(6498), pp. 1490-1495. (doi: 10.1126/science.aba6630) (PMID:32587021)
Azmi, L., Bragginton, E. C., Cadby, I. T., Byron, O. , Roe, A. J. , Lovering, A. L. and Gabrielsen, M. (2020) High-resolution structure of the alcohol dehydrogenase domain of the bifunctional bacterial enzyme AdhE. Acta Crystallographica. Section F: Structural Biology Communications, 76(9), pp. 414-421. (doi: 10.1107/S2053230X20010237)
Ballester-Lopez, A. et al. (2020) Preliminary findings on CTG expansion determination in different tissues from patients with myotonic dystrophy type 1. Genes, 11(11), 1321. (doi: 10.3390/genes11111321) (PMID:33171734) (PMCID:PMC7695006)
Ballester-Lopez, A. et al. (2020) The need for establishing a universal CTG sizing method in myotonic dystrophy type 1. Genes, 11(7), 757. (doi: 10.3390/genes11070757) (PMID:32645888)
Ballester‐Lopez, A. et al. (2020) A DM1 family with interruptions associated with atypical symptoms and late onset but not with a milder phenotype. Human Mutation, 41(2), pp. 420-431. (doi: 10.1002/humu.23932) (PMID:31608518)
Battle, M. W., Vegliani, F. and Jones, M. A. (2020) Shades of green: untying the knots of green photoperception. Journal of Experimental Botany, 71(19), pp. 5764-5770. (doi: 10.1093/jxb/eraa312) (PMID:32619226) (PMCID:PMC7541914)
Battle, M. W. and Jones, M. A. (2020) Cryptochromes integrate green light signals into the circadian system. Plant, Cell and Environment, 43(1), pp. 16-27. (doi: 10.1111/pce.13643) (PMID:31410859) (PMCID:PMC6973147)
Bjedov, I. et al. (2020) Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in drosophila. PLoS Genetics, 16(11), e1009083. (doi: 10.1371/journal.pgen.1009083) (PMID:33253201) (PMCID:PMC7738165)
Blair, C. M., Ling, J. and Baillie, G. S. (2020) Measuring cAMP specific phosphodiesterase activity: a two-step radioassay. Bio-Protocol, 10(7), e3581. (doi: 10.21769/BioProtoc.3581) (PMID:33659551) (PMCID:PMC7842805)
Bradley, S. J. et al. (2020) Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs. Nature Chemical Biology, 16(3), pp. 240-249. (doi: 10.1038/s41589-019-0453-9) (PMID:32080630)
Breton, É., Légaré, C., Overend, G. , Guay, S.-P., Monckton, D. , Mathieu, J., Gagnon, C., Richer, L., Gallais, B. and Bouchard, L. (2020) DNA methylation at the DMPK gene locus is associated with cognitive functions in myotonic dystrophy type 1. Epigenomics, 12(23), pp. 2051-2064. (doi: 10.2217/epi-2020-0328) (PMID:33301350)
Butt, G. R., Qayyum, Z. A. and Jones, M. A. (2020) Plant defence mechanisms are modulated by the circadian system. Biology, 9(12), 454. (doi: 10.3390/biology9120454)
Cabrero, P. , Terhzaz, S. , Dornan, A. J. , Ghimire, S., Holmes, H. L., Turin, D. R., Romero, M. F., Davies, S. and Dow, J. A.T. (2020) Specialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubule. Proceedings of the National Academy of Sciences of the United States of America, 117(3), pp. 1779-1787. (doi: 10.1073/pnas.1915943117) (PMID:31907321) (PMCID:PMC6983416)
Cañadas-Lozano, D., Marín-Aguilar, F., Castejón-Vega, B. , Ryffel, B., Navarro-Pando, J. M., Ruiz-Cabello, J., Alcocer-Gómez, E., Bullón, P. and Cordero, M. D. (2020) Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice. GeroScience, 42(2), pp. 715-725. (doi: 10.1007/s11357-019-00151-6) (PMID:31975052) (PMCID:PMC7206474)
Cantini, M. , Donnelly, H. , Dalby, M. J. and Salmeron-Sanchez, M. (2020) The plot thickens: the emerging role of matrix viscosity in cell mechanotransduction. Advanced Healthcare Materials, 9(8), 1901259. (doi: 10.1002/adhm.201901259) (PMID:31815372)
Cao, X., Lilla, S., Cao, Z., Pringle, M. A., Oka, O. B.V. , Robinson, P. J. , Szmaja, T., Van Lith, M., Zanivan, S. and Bulleid, N. (2020) The mammalian cytosolic thioredoxin reductase pathway acts via a membrane 1 protein to reduce ER-localised proteins. Journal of Cell Science, 133, jcs241976. (doi: 10.1242/jcs.241976) (PMID:32184267) (PMCID:PMC7197872)
Cerullo, A. R. et al. (2020) Comparative animal mucomics: inspiration for functional materials from ubiquitous and understudied biopolymers. ACS Biomaterials Science and Engineering, 6(10), pp. 5377-5398. (doi: 10.1021/acsbiomaterials.0c00713) (PMID:33320564)
Chatrin, C., Gabrielsen, M. , Buetow, L., Nakasone, M. A., Ahmed, S. F., Sumpton, D., Sibbet, G. J., Smith, B. O. and Huang, D. T. (2020) Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases. Science Advances, 6(38), eabc0418. (doi: 10.1126/sciadv.abc0418) (PMID:32948590) (PMCID:PMC7500938)
Chaugule, V. K., Arkinson, C., Rennie, M. L. , Kämäräinen, O., Toth, R. and Walden, H. (2020) Allosteric mechanism for site-specific ubiquitination of FANCD2. Nature Chemical Biology, 16, pp. 291-301. (doi: 10.1038/s41589-019-0426-z) (PMID:31873223)
Childs, P. G., Reid, S., Salmeron-Sanchez, M. and Dalby, M. J. (2020) Hurdles to uptake of mesenchymal stem cells and their progenitors in therapeutic products. Biochemical Journal, 477(17), pp. 3349-3366. (doi: 10.1042/BCJ20190382) (PMID:32941644) (PMCID:PMC7505558)
Cohen, E., Sawyer, J. K., Peterson, N. G., Dow, J. A.T. and Fox, D. T. (2020) Physiology, development, and disease modeling in the Drosophila excretory system. Genetics, 214(2), pp. 235-264. (doi: 10.1534/genetics.119.302289) (PMID:32029579) (PMCID:PMC7017010)
Crecente Garcia, S., Neckebroeck, A., Clark, J. S. , Smith, B. O. and Thomson, A. R. (2020) β-turn mimics by chemical ligation. Organic Letters, 22(11), pp. 4424-4428. (doi: 10.1021/acs.orglett.0c01427) (PMID:32406695) (PMCID:PMC7304061)
de Rooij, P. G.H., Perrella, G., Kaiserli, E. and van Zanten, M. (2020) The diverse and unanticipated roles of Histone deacetylase 9 in coordinating plant development and environmental acclimation. Journal of Experimental Botany, 71(20), pp. 6211-6225. (doi: 10.1093/jxb/eraa335) (PMID:32687569) (PMCID:PMC7586748)
Donald, C. L. , Siriyasatien, P. and Kohl, A. (2020) Toxorhynchites species: A review of current knowledge. Insects, 11(11), 747. (doi: 10.3390/insects11110747)
Dornan, A.J. , Halberg, K.A., Beuter, L.-K., Davies, S.-A. and Dow, J.A.T. (2020) The septate junction protein Snakeskin is critical for epithelial barrier function and tissue homeostasis in the Malpighian tubules of adult Drosophila. bioRxiv, (doi: 10.1101/2020.12.14.422678)
Edwards, R., Gerlich, S. and Tokatlidis, K. (2020) The biogenesis of mitochondrial intermembrane space proteins. Biological Chemistry, 401(6-7), pp. 737-747. (doi: 10.1515/hsz-2020-0114) (PMID:32061164)
Ellis, N. et al. (2020) Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s Disease. Biological Psychiatry, 87(9), pp. 857-865. (doi: 10.1016/j.biopsych.2019.12.010) (PMID:32087949)
Fasciani, I., Petragnano, F., Aloisi, G., Marampon, F., Carli, M., Scarselli, M., Maggio, R. and Rossi, M. (2020) Allosteric modulators of G protein-coupled dopamine and serotonin receptors: a new class of atypical antipsychotics. Pharmaceuticals, 13(11), 388. (doi: 10.3390/ph13110388) (PMID:33202534) (PMCID:PMC7696972)
Flower, M., Lomeikaite, V., Holmans, P., Jones, L., Tabrizi, S. J. and Monckton, D. G. (2020) Reply: The repeat variant in MSH3 is not a genetic modifier for spinocerebellar ataxia type 3 and Friedreich’s ataxia. Brain, 143(4), e26. (doi: 10.1093/brain/awaa044) (PMID:32154840)
Flütsch, S., Wang, Y., Takemiya, A., Vialet-Chabrand, S. R., Klejchova, M., Nigro, A., Hills, A., Lawson, T., Blatt, M. R. and Santelia, D. (2020) Guard cell starch degradation yields glucose for rapid stomatal opening in Arabidopsis. Plant Cell, 32(7), pp. 2325-2344. (doi: 10.1105/tpc.18.00802) (PMID:32354788)
Frost, M. G., Mazloumi Aboukheili, A. M., Toth, R. and Walden, H. (2020) Characterisation of FANCL variants observed in patient cancer cells. Bioscience Reports, 40(6), 20191304. (doi: 10.1042/BSR20191304) (PMID:32420600) (PMCID:PMC7273913)
Gallego, P., Castejón-Vega, B. , del Campo, J. A. and Cordero, M. D. (2020) The absence of NLRP3-inflammasome modulates hepatic fibrosis progression, lipid metabolism, and inflammation in KO NLRP3 mice during aging. Cells, 9(10), 2148. (doi: 10.3390/cells9102148) (PMID:32977490) (PMCID:PMC7598267)
Gardiner, A., Nguyen-Phan, T. C. and Cogdell, R. J. (2020) A comparative look at structural variation among RC-LH1 ‘core’ complexes present in anoxygenic phototrophic bacteria. Photosynthesis Research, 145(2), pp. 83-96. (doi: 10.1007/s11120-020-00758-3) (PMID:32430765) (PMCID:PMC7423801)
Gellings, E., Cogdell, R. J. and van Hulst, N. F. (2020) Room-temperature excitation-emission spectra of single LH2 complexes show remarkably little variation. Journal of Physical Chemistry Letters, 11(7), pp. 2430-2435. (doi: 10.1021/acs.jpclett.0c00375) (PMID:32142282)
Gilroy, J., McInerny, C. , Dudley, S., Balmer, D., Batty, C., French, P., Lees, A., Musgrove, A. and Stoddart, A. (2020) British Ornithologists’ Union Records Committee (BOURC): 51st Report (January 2020). Ibis, 162(2), pp. 600-603. (doi: 10.1111/ibi.12817)
Gök, C. , Plain, F., Robertson, A., Howie, J., Baillie, G. S. , Fraser, N. J. and Fuller, W. (2020) Dynamic palmitoylation of the sodium-calcium exchanger modulates its structure, affinity for lipid ordered domains, and inhibition by XIP. Cell Reports, 31(10), 107697. (doi: 10.1016/j.celrep.2020.107697) (PMID:32521252) (PMCID:PMC7296346)
Gray, S. C., Kinghorn, K. J. and Woodling, N. S. (2020) Shifting equilibriums in Alzheimer's disease: The complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis. Neural Regeneration Research, 15(7), pp. 1208-1219. (doi: 10.4103/1673-5374.272571) (PMID:31960800) (PMCID:PMC7047786)
Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)
Hailstone, M., Waithe, D., Samuels, T. J., Yang, L., Costello, I., Arava, Y., Robertson, E., Parton, R. M. and Davis, I. (2020) CytoCensus, mapping cell identity and division in tissues and organs using machine learning. eLife, 9, e51085. (doi: 10.7554/eLife.51085) (PMID:32423529) (PMCID:PMC7237217)
Harrop, A., Gilroy, J., McInerny, C. , Dudley, S., Balmer, D., Batty, C., French, P., Lees, A., Musgrove, A. and Stoddart, A. (2020) British Ornithologists’ Union Records Committee ( BOURC ): 50th Report (October 2019). Ibis, 162(1), pp. 263-268. (doi: 10.1111/ibi.12762)
Hart, A. (2020) Cover illustration: "Lockdown" mural, Bath Street, Glasgow, by the.rebel.bear Unshackling Plastic Surgery from COVID-19. Journal of Plastic, Reconstructive and Aesthetic Surgery, 73(6), pp. 1009-1011. (doi: 10.1016/j.bjps.2020.05.082) (PMID:32553186) (PMCID:PMC7293883)
Hay, L. K. et al. (2020) Analysis of dose using CBCT and synthetic CT during head and neck radiotherapy: A single centre feasibility study. Technical Innovations and Patient Support in Radiation Oncology, 14, pp. 21-29. (doi: 10.1016/j.tipsro.2020.02.004) (PMID:32226833) (PMCID:PMC7093804)
Hepworth, J. et al. (2020) Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes. eLife, 9, e57671. (doi: 10.7554/eLife.57671) (PMID:32902380) (PMCID:PMC7518893)
Higgins, G.C., Thomson, S.E., Roditi, G., Riehle, M.O. , Murnaghan, C. and Hart, A.M. (2020) Anatomically accurate 3D modelling and printing in a case of obstetric brachial plexus injury. JPRAS Open, 24, pp. 7-11. (doi: 10.1016/j.jpra.2020.02.003) (PMCID:PMC7113606)
Higgins, G. and Thomson, S. E. (2020) The introduction of plastic and reconstructive surgery to the University of Glasgow undergraduate medical core curriculum. Postgraduate Medical Journal, 96(1132), pp. 64-66. (doi: 10.1136/postgradmedj-2019-137046)
Horaruang, W., Hills, A. and Blatt, M. R. (2020) Communication between the plasma membrane and tonoplast is an emergent property of ion transport. Plant Physiology, 182, pp. 1833-1835. (doi: 10.1104/pp.19.01485) (PMID:31988199)
Hosseinzadeh, S., Lindsay, S. L. , Gallagher, A. G., Wellings, D. A., Riehle, M. O. , Riddell, J. S. and Barnett, S. C. (2020) A novel poly-ε-lysine based implant, Proliferate®, for promotion of CNS repair following spinal cord injury. Biomaterials Science, 8(13), pp. 3611-3627. (doi: 10.1039/D0BM00097C) (PMID:32515439)
Huethorst, E. , Cutiongco, M. F.A. , Campbell, F. A., Saeed, A. , Love, R., Reynolds, P. M. , Dalby, M. J. and Gadegaard, N. (2020) Customizable, engineered substrates for rapid screening of cellular cues. Biofabrication, 12(2), 025009. (doi: 10.1088/1758-5090/ab5d3f) (PMID:31783378) (PMCID:PMC7655147)
Inoue, S.‐I. et al. (2020) CIPK23 regulates blue light-dependent stomatal opening in Arabidopsis thaliana. Plant Journal, 104(3), pp. 679-692. (doi: 10.1111/tpj.14955) (PMID:32780529)
Jarad, M., Antoniou-Kourounioti, R. L. , Hepworth, J. and Qüesta, J. I. (2020) Unique and contrasting effects of light and temperature cues on plant transcriptional programs. Transcription, 11(3-4), pp. 134-159. (doi: 10.1080/21541264.2020.1820299) (PMID:33016207) (PMCID:PMC7714439)
Javitt, G., Cao, Z., Resnick, E., Gabizon, R., Bulleid, N. and Fass, D. (2020) Structure and electron-transfer pathway of the human methionine sulfoxide reductase MsrB3. Antioxidants and Redox Signaling, 33(10), pp. 665-678. (doi: 10.1089/ars.2020.8037) (PMID:32517586) (PMCID:PMC7475093)
Jezek, M., Hills, A., Blatt, M. R. and Lew, V. L. (2020) A constraint-relaxation-recovery mechanism for stomatal dynamics. Plant, Cell and Environment, 42(8), pp. 2399-2410. (doi: 10.1111/pce.13568) (PMID:31032976) (PMCID:PMC6771799)
Kakkar, T. et al. (2020) Superchiral near fields detect virus structure. Light: Science and Applications, 9(1), 195. (doi: 10.1038/s41377-020-00433-1) (PMID:33298854) (PMCID:PMC7705013)
Khajehali, E., Bradley, S. , van der Westhuizen, E. T., Molloy, C. , Valant, C., Finlayson, L. , Lindsley, C. W., Sexton, P. M., Tobin, A. B. and Christopoulos, A. (2020) Restoring agonist function at a chemogenetically modified M1 muscarinic acetylcholine receptor. ACS Chemical Neuroscience, 11(24), pp. 4270-4279. (doi: 10.1021/acschemneuro.0c00540) (PMID:33196174)
Khordadpoor Deilamani, F. and Taghi Akbari, M. (2020) First report of preimplantation genetic diagnosis for steroid-resistant nephrotic syndrome. Journal of Human Genetics and Genomics, 3(1), e109109. (doi: 10.5812/jhgg.109109)
Khordadpour Deilamani, F. and Taghi Akbari, M. (2020) Preimplantation genetic diagnosis for beta thalassemia. Journal of Human Genetics and Genomics, 3(1), e109503. (doi: 10.5812/jhgg.109503)
Kim, K.-H. et al. (2020) Genetic and functional analyses point to FAN1 as the source of multiple Huntington disease modifier effects. American Journal of Human Genetics, 107(1), pp. 96-110. (doi: 10.1016/j.ajhg.2020.05.012) (PMID:32589923) (PMCID:PMC7332667)
Klejchová, M., Hills, A. and Blatt, M. R. (2020) Predicting the unexpected in stomatal gas exchange: not just an open-and-shut case. Biochemical Society Transactions, 48(3), pp. 881-889. (doi: 10.1042/BST20190632) (PMID:32453378) (PMCID:PMC7329339)
Kounatidis, I. et al. (2020) 3D correlative cryo-structured illumination fluorescence and soft X-ray microscopy elucidates reovirus intracellular release pathway. Cell, 182(2), 515-530.e17. (doi: 10.1016/j.cell.2020.05.051) (PMID:32610083) (PMCID:PMC7391008)
Kurkiewicz, A. et al. (2020) Towards development of a statistical framework to evaluate myotonic dystrophy type 1 mRNA biomarkers in the context of a clinical trial. PLoS ONE, 15(4), e0231000. (doi: 10.1371/journal.pone.0231000) (PMID:32287265) (PMCID:PMC7156058)
Labéguère, F. et al. (2020) Discovery of 9-Cyclopropylethynyl-2-((S)-1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one (GLPG1205), a unique GPR84 negative allosteric modulator undergoing evaluation in a phase II clinical trial. Journal of Medicinal Chemistry, 63(22), pp. 13526-13545. (doi: 10.1021/acs.jmedchem.0c00272) (PMID:32902984)
Landfeldt, E., Nikolenko, N., Jimenez‑Moreno, C., Cumming, S., Monckton, D. , Faber, C. G., Merkies, I. S.J., Gorman8, G., Turner, C. and Lochmüller, H. (2020) Change over time in ability to perform activities of daily living in myotonic dystrophy type 1. Journal of Neurology, 267(11), pp. 3235-3242. (doi: 10.1007/s00415-020-09970-6) (PMID:32542526) (PMCID:PMC7578145)
Landfeldt, E., Nikolenko, N., Jimenez‐Moreno, C., Cumming, S., Monckton, D. G. , Faber, C. G., Merkies, I. S.J., Gorman, G., Turner, C. and Lochmüller, H. (2020) Activities of daily living in myotonic dystrophy type 1. Acta Neurologica Scandinavica, 141(5), pp. 380-387. (doi: 10.1111/ane.13215) (PMID:31889295)
Larson, E. R., Ortmannová, J., Donald, N. A., Alvim, J., Blatt, M. R. and Žárský, V. (2020) Synergy among exocyst and SNARE interactions identifies a functional hierarchy in secretion during vegetative growth. Plant Cell, 32(9), pp. 2951-2963. (doi: 10.1105/tpc.20.00280) (PMID:32699172)
Lefoulon, C., Boxall, S. F., Hartwell, J. and Blatt, M. R. (2020) Crassulacean acid metabolism guard cell anion channel activity follows transcript abundance and is suppressed by apoplastic malate. New Phytologist, 227(6), pp. 1847-1857. (doi: 10.1111/nph.16640) (PMID:32367511)
Lenton, S., Wang, Q., Nylander, T., Teixeira, S. and Holt, C. (2020) Structural biology of calcium phosphate nanoclusters sequestered by phosphoproteins. Crystals, 10(9), 755. (doi: 10.3390/cryst10090755)
Liao, X., Liu, W. , Yang, H.-Q. and Jenkins, G. I. (2020) A dynamic model of UVR8 photoreceptor signaling in UV-B acclimated Arabidopsis. New Phytologist, 227(3), pp. 857-866. (doi: 10.1111/nph.16581) (PMID:32255498)
Ling, J., Blair, C. M. and Baillie, G. S. (2020) Fibrin Breakdown Assay. Bio-Protocol, 10(8), e3585. (doi: 10.21769/BioProtoc.3585)
Lu, A. T. et al. (2020) DNA methylation study of Huntington's disease and motor progression in patients and in animal models. Nature Communications, 11, 4529. (doi: 10.1038/s41467-020-18255-5) (PMID:32913184) (PMCID:PMC7484780)
Mahindra, A., Janha, O., Mapesa, K., Sanchez Azqueta, A., Alam, M. M. , Amambua-Ngwa, A., Nwakanma, D. C., Tobin, A. B. and Jamieson, A. G. (2020) Development of potent PfCLK3 inhibitors based on TCMDC-135051 as a new class of antimalarials. Journal of Medicinal Chemistry, 63(17), pp. 9300-9315. (doi: 10.1021/acs.jmedchem.0c00451) (PMID:32787140) (PMCID:PMC7497403)
Mähler, N., Schiffthaler, B., Robinson, K. M., Terebieniec, B. K., Vučak, M., Mannapperuma, C., Bailey, M. E.S. , Jansson, S., Hvidsten, T. R. and Street, N. R. (2020) Leaf shape in Populus tremula is a complex, omnigenic trait. Ecology and Evolution, 10(21), pp. 11922-11940. (doi: 10.1002/ece3.6691)
Marín‐Aguilar, F. et al. (2020) NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice. Aging Cell, 19(1), e13050. (doi: 10.1111/acel.13050) (PMID:31625260) (PMCID:PMC6974709)
Marti-Solano, M. et al. (2020) Combinatorial expression of GPCR isoforms affects signalling and drug responses. Nature, 587, pp. 650-656. (doi: 10.1038/s41586-020-2888-2) (PMID:33149304)
McFall, A. et al. (2020) UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: questionnaire and workshop proceedings. Journal of Cerebral Blood Flow and Metabolism, 40(7), pp. 1402-1414. (doi: 10.1177/0271678X20910552) (PMID:32151228) (PMCID:PMC7307003)
McFall, A. , Nicklin, S. A. and Work, L. M. (2020) The counter regulatory axis of the renin angiotensin system in the brain and ischaemic stroke: insight from preclinical stroke studies and therapeutic potential. Cellular Signalling, 76, 109809. (doi: 10.1016/j.cellsig.2020.109809) (PMID:33059037) (PMCID:PMC7550360)
McFarlane, M. et al. (2020) The Aedes aegypti Domino orthologue p400 regulates antiviral exogenous small interfering RNA pathway activity and ago-2 expression. mSphere, 5(2), e00081-20. (doi: 10.1128/mSphere.00081-20) (PMID:32269152) (PMCID:PMC7142294)
Melino, G. et al. (2020) Capsule endoscopy compatible fluorescence imager demonstrated using bowel cancer tumours. IEEE Sensors Journal, 20(17), pp. 9763-9771. (doi: 10.1109/JSEN.2020.2990293)
Miller, J. N., van der Plas, E., Hamilton, M., Koscik, T. R., Gutmann, L., Cumming, S. A., Monckton, D. G. and Nopoulos, P. C. (2020) Variant repeats within the DMPK CTG expansion protect function in myotonic dystrophy type 1. Neurology Genetics, 6(5), e504. (doi: 10.1212/NXG.0000000000000504) (PMID:32851192) (PMCID:PMC7428360)
Mitxitorena, I., Somma, D. , Mitchell, J. P., Lepistö, M., Tyrchan, C., Smith, E. L., Kiely, P. A., Walden, H. , Keeshan, K. and Carmody, R. J. (2020) The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits. Journal of Biological Chemistry, 295(33), pp. 11754-11763. (doi: 10.1074/jbc.RA120.014113) (PMID:32587091) (PMCID:PMC7450122)
Morris, J. et al. (2020) Exploring the role of contactins across psychological, psychiatric and cardiometabolic traits within UK Biobank. Genes, 11(11), 1326. (doi: 10.3390/genes11111326) (PMID:33182605) (PMCID:PMC7697406)
Morris, S. et al. (2020) Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes. PeerJ, 8, e8751. (doi: 10.7717/peerj.8751) (PMID:32185116) (PMCID:PMC7060922)
Nicolás-Ávila, J. A. et al. (2020) A network of macrophages supports mitochondrial homeostasis in the heart. Cell, 183(1), 94-109.e23. (doi: 10.1016/j.cell.2020.08.031) (PMID:32937105)
Nimmo, H. G. , Laird, J., Bindbeutel, R. and Nusinow, D. A. (2020) The evening complex is central to the difference between the circadian clocks of Arabidopsis thaliana shoots and roots. Physiologia Plantarum, 169(3), pp. 442-451. (doi: 10.1111/ppl.13108) (PMID:32303120)
O'Boyle, N., Berry, C. C. and Davies, R. L. (2020) Differentiated ovine tracheal epithelial cells support the colonisation of pathogenic and non-pathogenic strains of Mannheimia haemolytica. Scientific Reports, 10, 14971. (doi: 10.1038/s41598-020-71604-8) (PMID:32917945) (PMCID:PMC7486916)
Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
Parry, G. et al. (2020) How to build an effective research network: lessons from two decades of the GARNet plant science community. Journal of Experimental Botany, 71(22), pp. 6881-6889. (doi: 10.1093/jxb/eraa397) (PMID:32898228) (PMCID:PMC7906777)
Perrella, G., Vellutini, E., Zioutopoulou, A., Patitaki, E., Headland, L. R. and Kaiserli, E. (2020) Let it bloom: crosstalk between light and flowering signalling in Arabidopsis. Physiologia Plantarum, 169(3), pp. 301-311. (doi: 10.1111/ppl.13073) (PMID:32053223) (PMCID:PMC7383826)
Perrella, G., Zioutopoulou, A., Headland, L. R. and Kaiserli, E. (2020) The impact of light and temperature on chromatin organisation and plant adaptation. Journal of Experimental Botany, 71(17), pp. 5247-5255. (doi: 10.1093/jxb/eraa154) (PMID:32215554)
Phillips, M. A. et al. (2020) CryoSIM: super-resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultrastructural imaging. Optica, 7(7), pp. 802-812. (doi: 10.1364/optica.393203) (PMID:34277893) (PMCID:PMC8262592)
Prihandoko, R. et al. (2020) Pathophysiological regulation of lung function by the free fatty acid receptor FFA4. Science Translational Medicine, 12(557), eaaw9009. (doi: 10.1126/scitranslmed.aaw9009) (PMID:32817367)
Qüesta, J. I., Antoniou-Kourounioti, R. L. , Rosa, S., Li, P., Duncan, S., Whittaker, C., Howard, M. and Dean, C. (2020) Noncoding SNPs influence a distinct phase of Polycomb silencing to destabilize long-term epigenetic memory at Arabidopsis FLC. Genes and Development, 34, pp. 446-461. (doi: 10.1101/gad.333245.119) (PMID:32001513) (PMCID:PMC7050481)
Quon, T., Lin, L.-C., Ganguly, A. , Tobin, A. B. and Milligan, G. (2020) Therapeutic opportunities and challenges in targeting the orphan G protein-coupled receptor GPR35. ACS Pharmacology and Translational Science, 3(5), pp. 801-812. (doi: 10.1021/acsptsci.0c00079) (PMID:33073184)
Ratna, N., Kamble, N. L., Venkatesh, S. D. , Purushottam, M., Pal, P. K. and Jain, S. (2020) Psychiatric morbidity and poor follow-up underlie suboptimal functional and survival outcomes in Huntington’s disease. BMC Neurology, 20, 87. (doi: 10.1186/s12883-020-01671-x) (PMID:32164608) (PMCID:PMC7068943)
Reinhardt, C., Arena, G., Nedara, K., Edwards, R., Brenner, C., Tokatlidis, K. and Modjtahedi, N. (2020) AIF meets the CHCHD4/Mia40-dependent mitochondrial import pathway. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1866(6), 165746. (doi: 10.1016/j.bbadis.2020.165746) (PMID:32105825)
Rennie, M. L. , Chaugule, V. K. and Walden, H. (2020) Modes of allosteric regulation of the ubiquitination machinery. Current Opinion in Structural Biology, 62, pp. 189-196. (doi: 10.1016/j.sbi.2020.02.003) (PMID:32305021)
Rennie, M. L. , Lemonidis, K. , Arkinson, C., Chaugule, V. K. , Clarke, M. , Streetley, J. , Spagnolo, L. and Walden, H. (2020) Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA. EMBO Reports, 21(7), e50133. (doi: 10.15252/embr.202050133) (PMID:32510829) (PMCID:PMC7332966)
Rexen Ulven, E. et al. (2020) Structure-activity relationship studies of tetrahydroquinolone free fatty acid receptor 3 modulators. Journal of Medicinal Chemistry, 63(7), pp. 3577-3595. (doi: 10.1021/acs.jmedchem.9b02036) (PMID:32141297) (PMCID:PMC7307922)
Robinson, P. J. and Bulleid, N. J. (2020) Mechanisms of disulfide bond formation in nascent polypeptides entering the secretory pathway. Cells, 9(9), 1994. (doi: 10.3390/cells9091994) (PMID:32872499)
Robinson, P. J. , Kanemura, S., Cao, X. and Bulleid, N. J. (2020) Protein secondary structure determines the temporal relationship between folding and disulfide formation. Journal of Biological Chemistry, 295(8), pp. 2438-2448. (doi: 10.1074/jbc.RA119.011983) (PMID:31953323) (PMCID:PMC7039548)
Rodier, M., Keijzer, C., Milner, J. , Karimullah, A. S. , Barron, L., Gadegaard, N. , Lapthorn, A. J. and Kadodwala, M. (2020) Biomacromolecular charge chirality detected using chiral plasmonic nanostructures. Nanoscale Horizons, 5, pp. 336-344. (doi: 10.1039/C9NH00525K)
Rodríguez-Hernández, M. A. et al. (2020) Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer. Redox Biology, 36, 101510. (doi: 10.1016/j.redox.2020.101510) (PMID:32593127) (PMCID:PMC7322178)
Ronald, J. , McCarthy, K. and Davis, S. J. (2020) GIGANTEA integrates photoperiodic and temperature signals to time when growth occurs. Molecular Plant, 13(3), pp. 357-359. (doi: 10.1016/j.molp.2020.02.008) (PMID:32081594)
Rowland, S.-J., Boocock, M. R., Burke, M. E., Rice, P. A. and Stark, W. M. (2020) The protein-protein interactions required for assembly of the Tn3 resolution synapse. Molecular Microbiology, 114(6), pp. 952-965. (doi: 10.1111/mmi.14579) (PMID:33405333)
Royle, J. , Ramírez-Santana, C., Akpunarlieva, S., Donald, C. L. , Gestuveo, R. J., Anaya, J.-M., Merits, A., Burchmore, R. , Kohl, A. and Varjak, M. (2020) Glucose-regulated protein 78 interacts with Zika virus envelope protein and contributes to a productive infection. Viruses, 12(5), 524. (doi: 10.3390/v12050524)
Salimy, Z., Akbari, M.T. and Khordadpoor Deilamani, F. (2020) Assessment of FMR1 triplet repeats in patients affected with mental retardation, fragile X syndrome and primary ovarian insufficiency. Journal of Genetics, 99, 6. (doi: 10.1007/s12041-019-1171-5) (PMID:32089525)
Samuels, T. J., Arava, Y., Järvelin, A. I., Robertson, F., Lee, J. Y., Yang, L., Yang, C.-P., Lee, T., Ish-Horowicz, D. and Davis, I. (2020) Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation. Biology Open, 9(5), bio049684. (doi: 10.1242/bio.049684) (PMID:32205310) (PMCID:PMC7225087)
Samuels, T. J., Järvelin, A. I., Ish-Horowicz, D. and Davis, I. (2020) Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability. eLife, 9, e51529. (doi: 10.7554/eLife.51529) (PMID:31934860) (PMCID:PMC7025822)
Sarrigiannidis, S. O., Moussa, H., Dobre, O. , Dalby, M. J. , Tamimi, F. and Salmerón-Sánchez, M. (2020) Chiral tartaric acid improves fracture toughness of bioactive brushite-collagen bone cements. ACS Applied Bio Materials, 3(8), pp. 5056-5066. (doi: 10.1021/acsabm.0c00555) (PMID:32904797) (PMCID:PMC7461128)
Savino, A. M. et al. (2020) Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment depends on Stearoyl CoA desaturase. Nature Cancer, 1(10), pp. 998-1009. (doi: 10.1038/s43018-020-00115-2) (PMID:33479702) (PMCID:PMC7116605)
Scialò, F., Sriram, A., Stefanatos, R. , Spriggs, R. V., Loh, S. H.Y., Martins, L. M. and Sanz, A. (2020) Mitochondrial complex I derived ROS regulate stress adaptation in Drosophila melanogaster. Redox Biology, 32, 101450. (doi: 10.1016/j.redox.2020.101450) (PMID:32146156) (PMCID:PMC7264463)
Sencio, V. et al. (2020) Gut dysbiosis during influenza contributes to pulmonary pneumococcal superinfection through altered short-chain fatty acid production. Cell Reports, 30(9), 2934-2947.e6. (doi: 10.1016/j.celrep.2020.02.013) (PMID:32130898)
Shahzad, Z., Eaglesfield, R., Carr, C. and Amtmann, A. (2020) Cryptic variation in RNA-directed DNA-methylation controls lateral root development when auxin signaling is perturbed. Nature Communications, 11, 218. (doi: 10.1038/s41467-019-13927-3) (PMID:31924796) (PMCID:PMC6954204)
Skelton, F. C., Frowd, C. D., Hancock, P. J.B., Jones, H. S., Jones, B. C. , Fodarella, C., Battersby, K. and Logan, K. (2020) Constructing identifiable composite faces: the importance of cognitive alignment of interview and construction procedure. Journal of Experimental Psychology: Applied, 26(3), pp. 507-521. (doi: 10.1037/xap0000257) (PMID:31763863)
Sommer, M. E. et al. (2020) The European Research Network on Signal Transduction (ERNEST): toward a multidimensional holistic understanding of G protein-coupled receptor signaling. ACS Pharmacology and Translational Science, 3(2), pp. 361-370. (doi: 10.1021/acsptsci.0c00024) (PMID:32296774) (PMCID:PMC7155379)
Strawbridge, R. J. et al. (2020) Carotid intima-media thickness: novel loci, sex-specific effects, and genetic correlations with obesity and glucometabolic traits in UK Biobank. Arteriosclerosis, Thrombosis, and Vascular Biology, 40(2), pp. 446-461. (doi: 10.1161/ATVBAHA.119.313226) (PMID:31801372) (PMCID:PMC6975521)
Thompson, K. J. and Tobin, A. B. (2020) Crosstalk between the M1 muscarinic acetylcholine receptor and the endocannabinoid system: A relevance for Alzheimer's disease? Cellular Signalling, 70, 109545. (doi: 10.1016/j.cellsig.2020.109545) (PMID:31978506) (PMCID:PMC7184673)
Titlow, J., Robertson, F., Järvelin, A., Ish-Horowicz, D., Smith, C., Gratton, E. and Davis, I. (2020) Syncrip/hnRNP Q is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation. Journal of Cell Biology, 219(3), e201903135. (doi: 10.1083/jcb.201903135) (PMID:32040548) (PMCID:PMC7055005)
Tobin, A. B. and Bradley, S. J. (2020) Editorial for Advances in G Protein-Coupled Receptor Signal Transduction Special Issue. ACS Pharmacology and Translational Science, 3(2), pp. 169-170. (doi: 10.1021/acsptsci.0c00029) (PMID:32296759)
Trujillo, S. , Vega, S. L., Song, K. H., San Félix, A., Dalby, M. J. , Burdick, J. A. and Salmeron-Sanchez, M. (2020) Engineered full-length fibronectin-hyaluronic acid hydrogels for stem cell engineering. Advanced Healthcare Materials, 9(21), 2000989. (doi: 10.1002/adhm.202000989) (PMID:33002348)
Trujillo Munoz, S. , Gonzalez Garcia, C., Rico Tortosa, P., Reid, A., Windmill, J., Dalby, M. J. and Salmeron-Sanchez, M. (2020) Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors. Biomaterials, 252, 120104. (doi: 10.1016/j.biomaterials.2020.120104)
Truman, C. T.-S., Järvelin, A., Davis, I. and Castello, A. (2020) HIV rev-isited. Open Biology, 10(12), 200320. (doi: 10.1098/rsob.200320) (PMID:33352061) (PMCID:PMC7776567)
Vanaerschot, M. et al. (2020) Inhibition of resistance-refractory P. falciparum kinase PKG delivers prophylactic, blood stage, and transmission-blocking antiplasmodial activity. Cell Chemical Biology, 27(7), 806-816.e8. (doi: 10.1016/j.chembiol.2020.04.001) (PMID:32359426) (PMCID:PMC7369637)
Verweij, E. W. E., Al Araaj, B., Prabhata, W. R., Prihandoko, R., Nijmeijer, S., Tobin, A. B. , Leurs, R. and Vischer, H. F. (2020) Differential role of serines and threonines in intracellular loop 3 and C-terminal tail of the histamine H4 receptor in β-arrestin and G protein-coupled receptor kinase interaction, internalization, and signaling. ACS Pharmacology and Translational Science, 3(2), pp. 321-333. (doi: 10.1021/acsptsci.0c00008) (PMID:32296771) (PMCID:PMC7155198)
Visentin, S., Cannone, G., Doutch, J., Harris, G., Gleghorn, M. L., Clifton, L., Smith, B. O. and Spagnolo, L. (2020) A multi-pronged approach to understanding the form and function of hStaufen protein. RNA, 26(3), pp. 265-277. (doi: 10.1261/rna.072595.119)
Voigt, S., Sterz, K. R., Giehler, F., Mohr, A.-W., Wilson, J. B. , Moosmann, A. and Kieser, A. (2020) A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation. Nature Communications, 11, 685. (doi: 10.1038/s41467-020-14502-x) (PMID:32019925) (PMCID:PMC7000802)
Wang, H., Yang, G., Xiao, Y., Luo, G., Li, G. and Li, Z. (2020) Friend or foe? Essential roles of osteoclast in maintaining skeletal health. BioMed Research International, 2020, 4791786. (doi: 10.1155/2020/4791786)
Waraich, N. F., Jain, S., Colloms, S. D. , Stark, W. M. , Burton, N. P. and Maxwell, A. (2020) A novel decatenation assay for DNA topoisomerases using a singly-linked catenated substrate. BioTechniques, 69(5), pp. 356-362. (doi: 10.2144/btn-2020-0059) (PMID:33000631)
Ward, J. et al. (2020) The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function. Molecular Psychiatry, 25(11), pp. 3091-3099. (doi: 10.1038/s41380-019-0439-8) (PMID:31168069) (PMCID:PMC7116257)
Wei Chen, W., Takahashi, N., Hirata, Y., Ronald, J. , Porco, S., Davis, S. J., Nusinow, D. A., Kay, S. A. and Mas, P. (2020) A mobile ELF4 delivers circadian temperature information from shoots to roots. Nature Plants, 6, pp. 416-426. (doi: 10.1038/s41477-020-0634-2) (PMID:32284549) (PMCID:PMC7197390)
Witte, K., de Andrés, M. C., Wells, J., Dalby, M. J. , Salmeron-Sanchez, M. and Oreffo, R. O.C. (2020) Chondrobags: a high throughput alginate-fibronectin micromass platform for in vitro human cartilage formation. Biofabrication, 12(4), 045034. (doi: 10.1088/1758-5090/abb653)
Woodling, N. S. et al. (2020) The neuronal receptor tyrosine kinase Alk is a target for longevity. Aging Cell, 19(5), e13137. (doi: 10.1111/acel.13137) (PMID:32291952) (PMCID:PMC7253064)
Woodling, N. S. , Rajasingam, A., Minkley, L. J., Rizzo, A. and Partridge, L. (2020) Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling. BMC Biology, 18(1), 124. (doi: 10.1186/s12915-020-00854-9) (PMID:32928209) (PMCID:PMC7490873)
Xia, L. , Marquès-Bueno, M. M. and Karnik, R. (2020) Trafficking SNARE SYP132 partakes in auxin-associated root growth. Plant Physiology, 182, pp. 1836-1840. (doi: 10.1104/pp.19.01301) (PMID:31974128)
Yu, Y., Niccoli, T., Ren, Z., Woodling, N. S. , Aleyakpo, B., Szabadkai, G. and Partridge, L. (2020) PICALM rescues glutamatergic neurotransmission, behavioural function and survival in a Drosophila model of Aβ42 toxicity. Human Molecular Genetics, 29(14), pp. 2420-2434. (doi: 10.1093/hmg/ddaa125) (PMID:32592479) (PMCID:PMC7424762)
Zhang, Y., Bracken, H., Woolhead, C. and Zagnoni, M. (2020) Functionalisation of human chloride intracellular ion channels in microfluidic droplet-interface-bilayers. Biosensors and Bioelectronics, 150, 111920. (doi: 10.1016/j.bios.2019.111920) (PMID:31791876)
Zhao, Y., Antoniou-Kourounioti, R. L. , Calder, G., Dean, C. and Howard, M. (2020) Temperature-dependent growth contributes to long-term cold sensing. Nature, 583, pp. 825-829. (doi: 10.1038/s41586-020-2485-4) (PMID:32669706) (PMCID:PMC7116785)
Zhdanov, O. , Blatt, M. R. , Cammarano, A. , Zare-Behtash, H. and Busse, A. (2020) A new perspective on mechanical characterisation of Arabidopsis stems through vibration tests. Journal of the Mechanical Behavior of Biomedical Materials, 112, 104041. (doi: 10.1016/j.jmbbm.2020.104041)
Zou, Z.-G. et al. (2020) Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function. Clinical Science, 134(15), pp. 2019-2035. (doi: 10.1042/CS20200827) (PMID:32706027) (PMCID:PMC8299307)
Book Sections
Scarpa, M., Hesse, S. and Bradley, S. J. (2020) M1 muscarinic acetylcholine receptors: a therapeutic strategy for symptomatic and disease-modifying effects in Alzheimer's disease? In: Langmead, C. J. (ed.) From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors. Series: Advances in Pharmacology (88). Elsevier, pp. 277-310. ISBN 9780128201879 (doi: 10.1016/bs.apha.2019.12.003)
Williams, J. J.L., Baillie, G. S. and Palmer, T. M. (2020) Investigation of Novel Cavin-1/Suppressor of Cytokine Signaling 3 (SOCS3) Interactions by Coimmunoprecipitation, Peptide Pull-Down, and Peptide Array Overlay Approaches. In: Blouin, C. M. (ed.) Caveolae. Series: Methods in Molecular Biology (2169). Springer: New york, NY, pp. 105-118. ISBN 9781071607312 (doi: 10.1007/978-1-0716-0732-9_10)
Conference or Workshop Item
Barrena Díaz, A. J. and Wilson, J. (2020) Discovery of Human scFvs for CAR T-cells Using a Phage Display Library and a Yeast Display Platform. CAR-TCR Summit Europe, London, UK, 24-27 February 2020.
2019
Articles
Aguilera, G., Berry, C. C. , West, R. M., Gonzalez-Monterrubio, E., Angulo-Molina, A., Arias-Carrión, Ó. and Méndez-Rojas, M. Á. (2019) Carboxymethyl cellulose coated magnetic nanoparticles transport across a human lung microvascular endothelial cell model of the blood–brain barrier. Nanoscale Advances, 1(2), pp. 671-685. (doi: 10.1039/c8na00010g)
Alam, M. M. et al. (2019) Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science, 365(6456), eaau1682. (doi: 10.1126/science.aau1682) (PMID:31467193)
Alford, L., Marley, R., Dornan, A. , Dow, J. A.T. , Nachman, R. J. and Davies, S. A. (2019) Desiccation, thermal stress and associated mortality in Drosophila fruit flies induced by neuropeptide analogue treatment. Journal of Pest Science, 92, pp. 1123-1137. (doi: 10.1007/s10340-019-01100-0)
Alford, L., Marley, R., Dornan, A. , Pierre, J.-S., Dow, J. A.T. , Nachman, R. J. and Davies, S. A. (2019) Assessment of neuropeptide binding sites and the impact of biostable kinin and CAP2b analogue treatment on aphid (Myzus persicae and Macrosiphum rosae) stress tolerance. Pest Management Science, 75(6), pp. 1750-1759. (doi: 10.1002/ps.5372) (PMID:30734498) (PMCID:PMC6593983)
Bernassau, A. L., Riehle, M. O. , Desmulliez, M. P.Y., Andrade, M. A.B., Hantos, G. B. and Simon, G. (2019) Monte-Carlo based sensitivity analysis of acoustic sorting methods. Periodica Polytechnica Electrical Engineering and Computer Science, 63(2), pp. 68-76. (doi: 10.3311/PPee.13455)
Bernassau, A. L., Riehle, M. O. , Desmulliez, M. P.Y., Andrade, M. A.B. and Simon, G. (2019) Theoretical framework of radiation force in surface acoustic waves for modulated particle sorting. Periodica Polytechnica Electrical Engineering and Computer Science, 63(2), pp. 77-84. (doi: 10.3311/PPee.13454)
Bieniek, M., Llopis-Hernandez, V. , Douglas, K., Salmeron-Sanchez, M. and Lorenz, C. D. (2019) Minor chemistry changes alter surface hydration to control fibronectin adsorption and assembly into nanofibrils. Advanced Theory and Simulations, 2019(2), 1900169. (doi: 10.1002/adts.201900169)
Blackman, M. J. et al. (2019) Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents. PLoS Pathogens, 15(6), e1007722. (doi: 10.1371/journal.ppat.1007722) (PMID:31170268) (PMCID:PMC6553790)
Bolognini, D. et al. (2019) Chemogenetics defines receptor-mediated functions of short chain free fatty acids. Nature Chemical Biology, 15(5), pp. 489-498. (doi: 10.1038/s41589-019-0270-1) (PMID:30992568)
Bowman, P. R.T., Smith, G. L. and Gould, G. W. (2019) GLUT4 expression and glucose transport in human induced pluripotent stem cell-derived cardiomyocytes. PLoS ONE, 14(7), e0217885. (doi: 10.1371/journal.pone.0217885) (PMID:31920989) (PMCID:PMC6930865)
Bracken, H. A. and Woolhead, C. A. (2019) Increased freedom of movement in the nascent chain results in dynamic changes in the structure of the SecM arrest motif. Bioscience Reports, 39(1), BSR2018124. (doi: 10.1042/BSR20181246) (PMID:30563926) (PMCID:PMC6340945)
Brodsky, I. E. et al. (2019) Cathelicidin is a “fire alarm”, generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa. PLoS Pathogens, 15(4), e1007694. (doi: 10.1371/journal.ppat.1007694) (PMID:30978238) (PMCID:PMC6481867)
Caceres, C., Spatharis, S. , Kaiserli, E. , Smeti, E., Flowers, H. and Bonachela, J. A. (2019) Temporal phosphate gradients reveal diverse acclimation responses in phytoplankton phosphate uptake. ISME Journal, 13(11), pp. 2834-2845. (doi: 10.1038/s41396-019-0473-1) (PMID:31350454)
Calixto, C. P.G., Tzioutziou, N. A., James, A. B. , Hornyik, C., Guo, W., Zhang, R., Nimmo, H. G. and Brown, J. W.S. (2019) Cold-dependent expression and alternative splicing of Arabidopsis long non-coding RNAs. Frontiers in Plant Science, 10, 235. (doi: 10.3389/fpls.2019.00235) (PMID:30891054) (PMCID:PMC6413719)
Camacho, I. S., Theisen, A., Johannissen, L. O., Díaz-Ramos, L. A., Christie, J. M. , Jenkins, G. I. , Bellina, B., Barran, P. and Jones, A. R. (2019) Native mass spectrometry reveals the conformational diversity of the UVR8 photoreceptor. Proceedings of the National Academy of Sciences of the United States of America, 116(4), pp. 1116-1125. (doi: 10.1073/pnas.1813254116) (PMID:30610174) (PMCID:PMC6347689)
Campsie, P., Childs, P. G., Robertson, S. N., Cameron, K., Hough, J. , Salmeron-Sanchez, M. , Tsimbouri, P. M., Vichare, P., Dalby, M. J. and Reid, S. (2019) Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis. Scientific Reports, 9, 12944. (doi: 10.1038/s41598-019-49422-4) (PMID:31506561) (PMCID:PMC6736847)
Celis-Morales, C. A. et al. (2019) The combination of physical activity and sedentary behaviors modifies the genetic predisposition to obesity. Obesity, 27(4), pp. 653-661. (doi: 10.1002/oby.22417) (PMID:30900409)
Cheng, Z. A. et al. (2019) Nanoscale coatings for ultralow dose BMP‐2‐driven regeneration of critical‐sized bone defects. Advanced Science, 6(2), 1800361. (doi: 10.1002/advs.201800361) (PMID:30693176) (PMCID:PMC6343071)
Cherry, J. K. and Woolhead, C. A. (2019) Hydrophobicity, rather than secondary structure, is essential for the SRP dependent targeting of GPR35 to the ER membrane. Journal of Bioenergetics and Biomembranes, 51(2), pp. 137-150. (doi: 10.1007/s10863-019-9785-0) (PMID:30706279) (PMCID:PMC6439181)
Ciosi, M. et al. (2019) A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes. EBioMedicine, 48, pp. 568-580. (doi: 10.1016/j.ebiom.2019.09.020) (PMID:31607598) (PMCID:PMC6838430)
Conley, M. J. , McElwee, M., Azmi, L., Gabrielsen, M. , Byron, O. , Goodfellow, I. G. and Bhella, D. (2019) Calicivirus VP2 forms a portal-like assembly following receptor engagement. Nature, 565(7739), pp. 377-381. (doi: 10.1038/s41586-018-0852-1) (PMID:30626974)
Conte, E., Mende, L., Grainge, I. and Colloms, S. D. (2019) A mini-ISY100 transposon delivery system effective in γ proteobacteria. Frontiers in Microbiology, 10, 280. (doi: 10.3389/fmicb.2019.00280) (PMID:30873132) (PMCID:PMC6400869)
Corrales, E., Vásquez, M., Zhang, B., Santamaría-Ulloa, C., Cuenca, P., Krahe, R., Monckton, D. G. and Morales, F. (2019) Analysis of mutational dynamics at the DMPK (CTG)n locus identifies saliva as a suitable DNA sample source for genetic analysis in myotonic dystrophy type 1. PLoS ONE, 14(5), e0216407. (doi: 10.1371/journal.pone.0216407) (PMID:31048891) (PMCID:PMC6497304)
Cozens, D., Sutherland, E., Lauder, M., Taylor, G., Berry, C. C. and Davies, R. L. (2019) Pathogenic Mannheimia haemolytica invades differentiated bovine airway epithelial cells. Infection and Immunity, 87(6), e00078-19. (doi: 10.1128/IAI.00078-19) (PMID:30962401) (PMCID:PMC6529648)
Cumming, S. A. et al. (2019) Genetic determinants of disease severity in the myotonic dystrophy type 1 OPTIMISTIC cohort. Neurology, 93(10), e995-e1009. (doi: 10.1212/WNL.0000000000008056) (PMID:31395669) (PMCID:PMC6745735)
Debnath, S. et al. (2019) Tunable supramolecular gels by varying thermal history. Chemistry: A European Journal, 25(33), pp. 7881-7887. (doi: 10.1002/chem.201806281) (PMID:30945773)
Dobson, A. J. et al. (2019) Longevity is determined by ETS transcription factors in multiple tissues and diverse species. PLoS Genetics, 15(7), e1008212. (doi: 10.1371/journal.pgen.1008212) (PMID:31356597) (PMCID:PMC6662994)
Drdová, E. J., Klejchová, M. , Janko, K., Hála, M., Soukupová, H., Cvrčková, F. and Žárský, V. (2019) Developmental plasticity of Arabidopsis hypocotyl is dependent on exocyst complex function. Journal of Experimental Botany, 70(4), pp. 1255-1265. (doi: 10.1093/jxb/erz005) (PMID:30649396) (PMCID:PMC6382343)
Durham, G. A., Williams, J. J.L., Nasim, M. T. and Palmer, T. M. (2019) Targeting SOCS proteins to control JAK-STAT signalling in disease. Trends in Pharmacological Sciences, 40(5), pp. 298-308. (doi: 10.1016/j.tips.2019.03.001) (PMID:30948191)
Edwards, R. and Tokatlidis, K. (2019) The yeast voltage-dependent anion channel Porin: more IMPORTant than just metabolite transport. Molecular Cell, 73(5), pp. 861-862. (doi: 10.1016/j.molcel.2019.02.028) (PMID:30849391)
Farkash, E. A. and Leonard, D. A. (2019) Vascularized plexus allotransplantation: a new hope in brachial plexus palsy? Transplantation, 103(1), pp. 17-18. (doi: 10.1097/TP.0000000000002388) (PMID:30048400)
Findlay, E. G. et al. (2019) Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy. OncoImmunology, 8(8), 1608106. (doi: 10.1080/2162402X.2019.1608106) (PMID:31413918) (PMCID:PMC6682359)
Flower, M. et al. (2019) MSH3 modifies somatic instability and disease severity in Huntington's and myotonic dystrophy type 1. Brain, 142(7), pp. 1876-1886. (doi: 10.1093/brain/awz115) (PMID:31216018) (PMCID:PMC6598626)
Gao, H., Murugesan, B., Hoßbach, J., Evans, S. K., Stark, W. M. and Smith, M. C.M. (2019) Integrating vectors for genetic studies in the rare Actinomycete Amycolatopsis marina. BMC Biotechnology, 19, 32. (doi: 10.1186/s12896-019-0521-y) (PMID:31164159) (PMCID:PMC6549336)
Garcia-Moreno, M. et al. (2019) System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection. Molecular Cell, 74(1), pp. 196-211. (doi: 10.1016/j.molcel.2019.01.017) (PMID:30799147) (PMCID:PMC6458987)
Ghimire, S., Terhzaz, S. , Cabrero, P. , Romero, M. F., Davies, S. and Dow, J. A.T. (2019) Targeted renal knockdown of Na+/H+ exchanger regulatory factor Sip1 produces uric acid nephrolithiasis in Drosophila. American Journal of Physiology: Renal Physiology, 317(4), F930-F940. (doi: 10.1152/ajprenal.00551.2018) (PMID:31364377) (PMCID:PMC6843049)
Gould, G. , Bowman, P. and Smith, G. (2019) Cardiac SNARE expression in health and disease. Frontiers in Endocrinology, 10, 881. (doi: 10.3389/fendo.2019.00881) (PMID:31920989) (PMCID:PMC6930865)
Gray, S. et al. (2019) Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study. International Journal of Obesity, 43, pp. 1526-1538. (doi: 10.1038/s41366-019-0381-5) (PMID:31168053)
Gubina, N. et al. (2019) Essential physiological differences characterize short- and long-lived strains of Drosophila melanogaster. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 74(12), pp. 1835-1843. (doi: 10.1093/gerona/gly143) (PMID:29945183)
Gundogdu, M. and Walden, H. (2019) Structural basis of generic versus specific E2-RING E3 interactions in protein ubiquitination. Protein Science, 28(10), pp. 1758-1770. (doi: 10.1002/pro.3690) (PMID:31340062)
Harrison, J. U., Parton, R. M., Davis, I. and Baker, R. E. (2019) Testing models of mRNA localization reveals robustness regulated by reducing transport between cells. Biophysical Journal, 117(11), pp. 2154-2165. (doi: 10.1016/j.bpj.2019.10.025) (PMID:31708163) (PMCID:PMC6895595)
Hart, J. E., Sullivan, S. , Hermanowicz, P., Petersen, J., Diaz-Ramos, L. A., Hoey, D. J., Łabuz, J. and Christie, J. M. (2019) Engineering the phototropin photocycle improves photoreceptor performance and plant biomass production. Proceedings of the National Academy of Sciences of the United States of America, 116(25), pp. 12550-12557. (doi: 10.1073/pnas.1902915116) (PMID:31160455) (PMCID:PMC6589663)
Heskamp, L., van Nimwegen, M., Ploegmakers, M. J., Bassez, G., Deux, J.-F., Cumming, S. A., Monckton, D. G. , van Engelen, B. G.M. and Heerschap, A. (2019) Lower extremity muscle pathology in myotonic dystrophy type 1 assessed by quantitative MRI. Neurology, 92(24), e2803-e2814. (doi: 10.1212/WNL.0000000000007648) (PMID:31118244) (PMCID:PMC6598795)
Heuninck, J. et al. (2019) Context-dependent signaling of CXC chemokine receptor 4 and atypical chemokine receptor 3. Molecular Pharmacology, 96(6), pp. 778-793. (doi: 10.1124/mol.118.115477) (PMID:31092552)
Ibáñez-Shimabukuro, M. et al. (2019) Structure and ligand binding of As-p18, an extracellular fatty acid binding protein from the eggs of a parasitic nematode. Bioscience Reports, 39(7), BSR2019129. (doi: 10.1042/BSR20191292) (PMID:31273060) (PMCID:PMC6646235)
Ji, H., Wang, S., Cheng, C., Li, R., Wang, Z., Jenkins, G. I. , Kong, F. and Li, X. (2019) The RCC 1 family protein SAB 1 negatively regulates ABI 5 through multidimensional mechanisms during postgermination in Arabidopsis. New Phytologist, 222(2), pp. 907-922. (doi: 10.1111/nph.15653) (PMID:30570158)
Johnston, K. J.A., Adams, M. J., Nicholl, B. I. , Ward, J. , Strawbridge, R. , Ferguson, A., McIntosh, A., Bailey, M. E.S. and Smith, D. J. (2019) Genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 15(6), e1008164. (doi: 10.1371/journal.pgen.1008164) (PMID:31194737) (PMCID:PMC6592570)
Johnston, K. J.A., Adams, M. J., Nicholl, B. I. , Ward, J. , Strawbridge, R. , McIntosh, A., Smith, D. J. and Bailey, M. E.S. (2019) Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5. Translational Psychiatry, 9, 310. (doi: 10.1038/s41398-019-0613-4) (PMID:31748543) (PMCID:PMC6868167)
Jones, M. A. (2019) Retrograde signalling as an informant of circadian timing. New Phytologist, 221(4), pp. 1749-1753. (doi: 10.1111/nph.15525) (PMID:30299544)
Jones, M. A. , Morohashi, K., Grotewold, E. and Harmer, S. L. (2019) Arabidopsis JMJD5/JMJ30 acts independently of LUX ARRHYTHMO within the plant circadian clock to enable temperature compensation. Frontiers in Plant Science, 10, 57. (doi: 10.3389/fpls.2019.00057) (PMID:30774641) (PMCID:PMC6367231)
Jörg, M. et al. (2019) 6-Phenylpyrimidin-4-ones as positive allosteric modulators at the M1 mAChR: the determinants of allosteric activity. ACS Chemical Neuroscience, 10(3), pp. 1099-1114. (doi: 10.1021/acschemneuro.8b00613) (PMID:30547573)
Jurić, I., Hibberd, J. M., Blatt, M. and Burroughs, N. J. (2019) Computational modelling predicts substantial carbon assimilation gains for C3 plants with a single-celled C4 biochemical pump. PLoS Computational Biology, 15(9), e1007373. (doi: 10.1371/journal.pcbi.1007373) (PMID:31568503) (PMCID:PMC6786660)
Kareem, M. M., Hodgkinson, T., Salmeron-Sanchez, M. , Dalby, M. J. and Tanner, K. E. (2019) Hybrid core-shell scaffolds for bone tissue engineering. Biomedical Materials, 14(2), 025008. (doi: 10.1088/1748-605X/aafbf1) (PMID:30609417)
Karki, K. J., Chen, J., Sakurai, A., Shi, Q., Gardiner, A. T., Kühn, O., Cogdell, R. J. and Pullerits, T. (2019) Before Förster. Initial excitation in photosynthetic light harvesting. Chemical Science, 10(34), pp. 7923-7928. (doi: 10.1039/C9SC01888C) (PMID:31673317) (PMCID:PMC6788518)
Katwan, O. J., Alghamdi, F., Almabrouk, T. A. , Mancini, S. J., Kennedy, S. , Oakhill, J. S., Scott, J. W. and Salt, I. P. (2019) AMP-activated protein kinase complexes containing the β2 regulatory subunit are upregulated during and contribute to adipogenesis. Biochemical Journal, 476(12), pp. 1725-1740. (doi: 10.1042/BCJ20180714) (PMID:31189568) (PMCID:PMC6595317)
Keuss, M. J., Hjerpe, R., Hsia, O., Gourlay, R., Burchmore, R. , Trost, M. and Kurz, T. (2019) Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death. EMBO Journal, 38, e100024. (doi: 10.15252/embj.2018100024) (PMID:30804002) (PMCID:PMC6418418)
Knuhtsen, A., Whitmore, C., McWhinnie, F. S., McDougall, L., Whiting, R., Smith, B. O. , Timperley, C. M., Green, A. C., Kinnear, K. I. and Jamieson, A. G. (2019) α-conotoxin GI triazole-peptidomimetics: potent and stable blockers of a human acetylcholine receptor. Chemical Science, 10, pp. 1671-1676. (doi: 10.1039/C8SC04198A)
Kunsel, T., Tiwari, V., Matutes, Y. A., Gardiner, A. T., Cogdell, R. J. , Ogilvie, J. P. and Jansen, T. L. C. (2019) Simulating fluorescence-detected two-dimensional electronic spectroscopy of multichromophoric systems. Journal of Physical Chemistry B, 123(2), pp. 394-406. (doi: 10.1021/acs.jpcb.8b10176) (PMID:30543283) (PMCID:PMC6345114)
Landfeldt, E., Nikolenko, N., Jimenez-Moreno, C., Cumming, S., Monckton, D. G. , Gorman, G., Turner, C. and Lochmüller, H. (2019) Disease burden of myotonic dystrophy type 1. Journal of Neurology, 266(4), pp. 998-1006. (doi: 10.1007/s00415-019-09228-w) (PMID:30788616) (PMCID:PMC6420885)
Landry, G. M. et al. (2019) Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn2+ transporter. American Journal of Physiology: Renal Physiology, 316(2), F263-F273. (doi: 10.1152/ajprenal.00573.2017) (PMID:30520657)
Lee, J.-M. et al. (2019) CAG repeat not polyglutamine length determines timing of Huntington’s disease onset. Cell, 178(4), 887-900.e14. (doi: 10.1016/j.cell.2019.06.036)
Légaré, C., Overend, G. , Guay, S.-P., Monckton, D. G. , Mathieu, J., Gagnon, C. and Bouchard, L. (2019) gene DNA methylation levels are associated with muscular and respiratory profiles in DM1. Neurology Genetics, 5(3), e338. (doi: 10.1212/NXG.0000000000000338) (PMID:31334355) (PMCID:PMC6568328)
Lemonidis, K. , Salih, T. S., Dancer, S. J., Hunter, I. S. and Tucker, N. P. (2019) Emergence of an Australian-like pstS-null vancomycin resistant Enterococcus faecium clone in Scotland. PLoS ONE, 14(6), e0218185. (doi: 10.1371/journal.pone.0218185) (PMID:31194809) (PMCID:PMC6563996)
Leonard, D. A. (2019) Commentary on "An experimental rodent model of whole eye transplantation for assessment of viability and immunological outcomes". Journal of Plastic, Reconstructive and Aesthetic Surgery, 72(10), pp. 1651-1652. (doi: 10.1016/j.bjps.2019.05.043) (PMID:31175033)
Liao, X., Zhang, B. , Blatt, M. R. and Jenkins, G. I. (2019) A FRET method for investigating dimer/monomer status and conformation of the UVR8 photoreceptor. Photochemical and Photobiological Sciences, 18(2), pp. 367-374. (doi: 10.1039/C8PP00489G) (PMID:30534791) (PMCID:PMC6374739)
Mackenzie, A. E., Quon, T., Lin, L.-C., Hauser, A. S., Jenkins, L. , Inoue, A., Tobin, A. B. , Gloriam, D. E., Hudson, B. D. and Milligan, G. (2019) Receptor selectivity between the G proteins Gα12 and Gα13 is defined by a single leucine-to-isoleucine variation. FASEB Journal, 33(4), pp. 5005-5017. (doi: 10.1096/fj.201801956R) (PMID:30601679) (PMCID:PMC6436656)
Mancini, S., Mahmud, Z. A., Jenkins, L. , Bolognini, D., Newman, R., Barnes, M., Edye, M. E., McMahon, S. B., Tobin, A. B. and Milligan, G. (2019) On-target and off-target effects of novel orthosteric and allosteric activators of GPR84. Scientific Reports, 9, 1861. (doi: 10.1038/s41598-019-38539-1) (PMID:30755705) (PMCID:PMC6372602)
Martinez Corrales, G., Cabrero, P. , Dow, J. A.T. , Terhzaz, S. and Davies, S. (2019) Novel roles for GATAe in growth, maintenance and proliferation of cell populations in the Drosophila renal tubule. Development, 146(9), dev178087. (doi: 10.1242/dev.178087) (PMID:31036543)
Mas-Moruno, C., Su, B. and Dalby, M. J. (2019) Multifunctional coatings and nanotopographies: towards cell instructive and antibacterial implants. Advanced Healthcare Materials, 8(1), 1801103. (doi: 10.1002/adhm.201801103) (PMID:30468010)
Meng, F., Liu, Q., Wang, X., Tan, D., Xue, L. and Barnes, W. J. P. (2019) Tree frog adhesion biomimetics: opportunities for the development of new, smart adhesives that adhere under wet conditions. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 377(2150), 20190131. (doi: 10.1098/rsta.2019.0131) (PMID:31177956)
Milligan, G. , Ward, R. J. and Marsango, S. (2019) GPCR homo-oligomerization. Current Opinion in Cell Biology, 57, pp. 40-47. (doi: 10.1016/j.ceb.2018.10.007) (PMID:30453145) (PMCID:PMC7083226)
Monckton, D. G. (2019) Manage risk of accidental gene editing of germline. Nature, 568(7753), p. 458. (doi: 10.1038/d41586-019-01284-6) (PMID:31015694)
Morris, J. et al. (2019) Genetic variation in CADM2 as a link between psychological traits and obesity. Scientific Reports, 9, 7339. (doi: 10.1038/s41598-019-43861-9) (PMID:31089183) (PMCID:PMC6517397)
Müskens, F. M., Ward, R. J., Herkt, D., van de Langemheen, H., Tobin, A. B. , Liskamp, R. M.J. and Milligan, G. (2019) Design, synthesis and evaluation of a diazirine photoaffinity probe for ligand-based receptor capture targeting G protein-coupled receptors. Molecular Pharmacology, 95(2), pp. 196-209. (doi: 10.1124/mol.118.114249) (PMID:30514721) (PMCID:PMC6324650)
O'Hara, A., Headland, L. R. , Díaz-Ramos, L. A., Morales, L. O., Strid, Å. and Jenkins, G. I. (2019) Regulation of Arabidopsis gene expression by low fluence rate UV-B independently of UVR8 and stress signaling. Photochemical and Photobiological Sciences, 18(7), pp. 1675-1684. (doi: 10.1039/C9PP00151D) (PMID:31218318)
Oka, O. B.V. , van Lith, M., Rudolf, J., Tungkum, W., Pringle, M.-A. and Bulleid, N. J. (2019) ERp18 regulates the activation of ATF6α during the unfolded protein response. EMBO Journal, 2019, e100990. (doi: 10.15252/embj.2018100990) (PMID:31209066)
Olorunniji, F. J., Lawson-Williams, M., McPherson, A. L., Paget, J. E., Stark, W. M. and Rosser, S. J. (2019) Control of ϕC31 integrase-mediated site-specific recombination by protein trans-splicing. Nucleic Acids Research, 47(21), pp. 11452-11460. (doi: 10.1093/nar/gkz936) (PMID:31667500) (PMCID:PMC6868429)
Overend, G. , Légaré, C., Mathieu, J., Bouchard, L., Gagnon, C. and Monckton, D. G. (2019) Allele length of the DMPK CTG repeat is a predictor of progressive myotonic dystrophy type 1 phenotypes. Human Molecular Genetics, 28(13), pp. 2245-2254. (doi: 10.1093/hmg/ddz055) (PMID:31220271)
Papanatsiou, M., Petersen, J., Henderson, L., Wang, Y., Christie, J.M. and Blatt, M.R. (2019) Optogenetic manipulation of stomatal kinetics improves carbon assimilation, water use, and growth. Science, 363(6434), pp. 1456-1459. (doi: 10.1126/science.aaw0046) (PMID:30923223)
Papanatsiou, M. (2019) MVApp flies its flag to the challenging frontier of multivariate data analysis. Plant Physiology, 180(3), pp. 1251-1252. (doi: 10.1104/pp.19.00454) (PMID:31253747)
Pulli, I. et al. (2019) Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells. Biochimica et Biophysica Acta: Molecular Cell Research, 1866(9), pp. 1475-1486. (doi: 10.1016/j.bbamcr.2019.06.006) (PMID:31220477)
Purohit, P. K., Edwards, R., Tokatlidis, K. and Saini, N. (2019) MiR-195 regulates mitochondrial function by targeting mitofusin-2 in breast cancer cells. RNA Biology, 16(7), pp. 918-929. (doi: 10.1080/15476286.2019.1600999) (PMID:30932749) (PMCID:PMC6546347)
Rehman, H. M., Cooper, J. W., Lam, H. M. and Yang, S. H. (2019) Legume biofortification is an underexploited strategy for combatting hidden hunger. Plant, Cell and Environment, 42(1), pp. 52-70. (doi: 10.1111/pce.13368) (PMID:29920691)
Robson, T. M. et al. (2019) A perspective on ecologically relevant plant-UV research and its practical application. Photochemical and Photobiological Sciences, 18(5), pp. 970-988. (doi: 10.1039/c8pp00526e) (PMID:30720036)
Rodier, M., Keijzer, C., Milner, J. , Karimullah, A. , Barron, L., Gadegaard, N. , Lapthorn, A. and Kadodwala, M. (2019) Probing specificity of protein-protein interactions with chiral plasmonic nanostructures. Journal of Physical Chemistry Letters, 10, pp. 6105-6111. (doi: 10.1021/acs.jpclett.9b02288) (PMID:31549842)
Rooney, W. M. , Wojnowska, M. and Walker, D. (2019) Draft genome sequence of the necrotrophic plant pathogenic bacterium Pectobacterium carotovorum subsp. carotovorum strain LMG 2410. Microbiology Resource Announcements, 8(31), e00614-19. (doi: 10.1128/MRA.00614-19) (PMID:31371540) (PMCID:PMC6675988)
Rühl, J. et al. (2019) Heterologous prime-boost vaccination protects against EBV antigen–expressing lymphomas. Journal of Clinical Investigation, 129(5), pp. 2071-2087. (doi: 10.1172/JCI125364) (PMID:30860494) (PMCID:PMC6486346)
Sadler, J. B.A., Lambert, C. A., Welburn, C. R., Adamson, I. S., Kioumourtzoglou, D., Chi, N.-W., Gould, G. W. and Bryant, N. J. (2019) The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes. Scientific Reports, 9, 4710. (doi: 10.1038/s41598-019-40596-5) (PMID:30886164) (PMCID:PMC6423145)
Sánchez-Aragón, M. , Cantisán-Gómez, J., Luque, C. M., Brás-Pereira, C., Lopes, C. S., Carmen Lemos, M. and Casares, F. (2019) A toggle-switch and a feed-forward loop engage in the control of the drosophila retinal determination gene network. Frontiers in Ecology and Evolution, 7, 2019. (doi: 10.3389/fevo.2019.00221)
Sharma, A., Sharma, B., Hayes, S., Kerner, K., Hoecker, U., Jenkins, G. I. and Franklin, K. A. (2019) UVR8 disrupts stabilisation of PIF5 by COP1 to inhibit plant stem elongation in sunlight. Nature Communications, 10, 4417. (doi: 10.1038/s41467-019-12369-1) (PMID:31562307) (PMCID:PMC6764944)
Simon, G., Andrade, M. A. B., Desmulliez, M. P.Y., Riehle, M. O. and Bernassau, A. L. (2019) Numerical determination of the secondary acoustic radiation force on a small sphere in a plane standing wave field. Micromachines, 10(7), 431. (doi: 10.3390/mi10070431)
Sprott, M. R. , Gallego-Ferrer, G., Dalby, M. J. , Salmeron-Sanchez, M. and Cantini, M. (2019) Functionalisation of PLLA with polymer brushes to trigger the assembly of fibronectin into nanonetworks. Advanced Healthcare Materials, 8(3), 1801469. (doi: 10.1002/adhm.201801469) (PMID:30609243)
Stoneman, M. R., Biener, G., Ward, R. J., Pediani, J. D. , Badu, D., Eis, A., Popa, I., Milligan, G. and Raicu, V. (2019) A general method to quantify ligand-driven oligomerization from fluorescence-based images. Nature Methods, 16(6), pp. 493-496. (doi: 10.1038/s41592-019-0408-9) (PMID:31110281)
Strawbridge, R. J. et al. (2019) Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide. EBioMedicine, 41, pp. 517-525. (doi: 10.1016/j.ebiom.2019.02.005) (PMID:30745170) (PMCID:PMC6442001)
Sullivan, S. , Kharshiing, E., Laird, J., Sakai, T. and Christie, J. M. (2019) Deetiolation enhances phototropism by modulating NON-PHOTOTROPIC HYPOCOTYL3 phosphorylation status. Plant Physiology, 180, pp. 1119-1131. (doi: 10.1104/pp.19.00206) (PMID:30918082) (PMCID:PMC6548275)
Tabudravu, J. N. et al. (2019) LC-HRMS-database screening metrics for rapid prioritization of samples to accelerate the discovery of structurally new natural products. Journal of Natural Products, 82(2), pp. 211-220. (doi: 10.1021/acs.jnatprod.8b00575) (PMID:30735391)
Taffet, E. J., Lee, B. G., Toa, Z. S. D., Pace, N., Rumbles, G., Southall, J. , Cogdell, R. J. and Scholes, G. D. (2019) Carotenoid nuclear reorganization and interplay of bright and dark excited states. Journal of Physical Chemistry B, 123(41), pp. 8628-8643. (doi: 10.1021/acs.jpcb.9b04027) (PMID:31553605)
Toste Rêgo, A. and da Fonseca, P. C.A. (2019) Characterization of fully recombinant human 20S and 20S-PA200 proteasome complexes. Molecular Cell, 76(1), 138-147.e5. (doi: 10.1016/j.molcel.2019.07.014) (PMID:31473102) (PMCID:PMC6863390)
van der Plas, E. et al. (2019) Brain structural features of myotonic dystrophy type 1 and their relationship with CTG repeats. Journal of Neuromuscular Diseases, 6(3), pp. 321-332. (doi: 10.3233/jnd-190397) (PMID:31306140)
van der Woude, L. C. et al. (2019) HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in Arabidopsis thaliana by mediating H2A.Z depletion. Proceedings of the National Academy of Sciences of the United States of America, 116(50), pp. 25343-25354. (doi: 10.1073/pnas.1911694116) (PMID:31767749) (PMCID:PMC6911240)
van Dorst, M., Okkersen, K., Kessels, R. P.C., Meijer, F. J.A., Monckton, D. G. , van Engelen, B. G.M., Tuladhar, A. M. and Raaphorst, J. (2019) Structural white matter networks in myotonic dystrophy type 1. NeuroImage: Clinical, 21, 101615. (doi: 10.1016/j.nicl.2018.101615) (PMID:30522973) (PMCID:PMC6413352)
van Kralingen, J., McFall, A. , Ord, E. N.J. , Coyle, T. F., Bissett, M., McClure, J. D. , McCabe, C. , Macrae, I. M., Dawson, J. and Work, L. M. (2019) Altered extracellular vesicle microrna expression in ischemic stroke and small vessel disease. Translational Stroke Research, 10(5), pp. 495-508. (doi: 10.1007/s12975-018-0682-3) (PMID:30617992) (PMCID:PMC6733813)
Vaz, F., Kounatidis, I., Covas, G., Parton, R. M., Harkiolaki, M., Davis, I. , Filipe, S. R. and Ligoxygakis, P. (2019) Accessibility to peptidoglycan is important for the recognition of gram-positive bacteria in Drosophila. Cell Reports, 27(8), 2480-2492.e6. (doi: 10.1016/j.celrep.2019.04.103) (PMID:31116990) (PMCID:PMC6533200)
Vuckovic, Z. et al. (2019) Crystal structure of the M5 muscarinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America, 116(51), pp. 26001-26007. (doi: 10.1073/pnas.1914446116) (PMID:31772027) (PMCID:PMC6926013)
Waghmare, S. , Lefoulon, C., Zhang, B. , Lileikyte, E., Donald, N. and Blatt, M. (2019) K+ channel and SEC11 binding exchange regulates SNARE assembly for secretory traffic. Plant Physiology, 181, pp. 1096-1113. (doi: 10.1104/pp.19.00919) (PMID:31548266)
Ward, J. et al. (2019) Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure. Translational Psychiatry, 9, 327. (doi: 10.1038/s41398-019-0635-y) (PMID:31797917) (PMCID:PMC6892870)
Wiejak, J., van Basten, B., Hamilton, G. and Yarwood, S. J. (2019) Genome-wide mapping defines a role for C/EBPβ and c-Jun in non-canonical cyclic AMP signalling. Cells, 8(10), e1253. (doi: 10.3390/cells8101253)
Wilkinson, C. M., Roughley, M., Moffat, R. D., Monckton, D. G. and MacGregor, M. (2019) In search of Robert Bruce, part I: craniofacial analysis of the skull excavated at Dunfermline in 1819. Journal of Archaeological Science: Reports, 24, pp. 556-564. (doi: 10.1016/j.jasrep.2019.02.018)
Xia, L. , Marques-Bueno, M. M., Bruce, C. G. and Karnik, R. (2019) Unusual roles of secretory SNARE SYP132 in plasma membrane H+-ATPase traffic and vegetative plant growth. Plant Physiology, 180(2), pp. 837-858. (doi: 10.1104/pp.19.00266) (PMID:30926657)
Zhang, B. , Karnik, R. , Alvim, J., Donald, N. and Blatt, M. R. (2019) Dual sites for SEC11 on the SNARE SYP121 implicate a binding exchange during secretory traffic. Plant Physiology, 180, pp. 228-239. (doi: 10.1104/pp.18.01315) (PMID:30850468) (PMCID:PMC6501095)
Zhao, C. et al. (2019) Evolution of chloroplast retrograde signaling facilitates green plant adaptation to land. Proceedings of the National Academy of Sciences of the United States of America, 116(11), pp. 5015-5020. (doi: 10.1073/pnas.1812092116) (PMID:30804180) (PMCID:PMC6421419)
Zhao, J., Pokhilko, A., Ebenhöh, O., Rosser, S. J. and Colloms, S. D. (2019) A single-input binary counting module based on serine integrase site-specific recombination. Nucleic Acids Research, 47(9), pp. 4896-4909. (doi: 10.1093/nar/gkz245) (PMID:30957849) (PMCID:PMC6511857)
Žurauskas, M., Dobbie, I. M., Parton, R. M., Phillips, M. A., Göhler, A., Davis, I. and Booth, M. J. (2019) IsoSense: frequency enhanced sensorless adaptive optics through structured illumination. Optics Express, 6(3), pp. 370-379. (doi: 10.1364/optica.6.000370) (PMID:31417942) (PMCID:PMC6683765)
Book Sections
Chaugule, V. K., Arkinson, C., Toth, R. and Walden, H. (2019) Enzymatic preparation of monoubiquitinated FANCD2 and FANCI proteins. In: Hochstrasser, M. (ed.) Ubiquitin and Ubiquitin-like Protein Modifiers. Series: Methods in Enzymology, 618 (618). Elsevier, pp. 73-104. ISBN 9780128163597 (doi: 10.1016/bs.mie.2018.12.021)
Davies, S.-A. , Cabrero, P. , Marley, R., Martinez-Corrales, G., Ghimire, S., Dornan, A. J. and Dow, J. A.T. (2019) Epithelial function in the Drosophila Malpighian tubule: an in vivo renal model. In: Vainio, S. (ed.) Kidney Organogenesis: Methods and Protocols. Series: Methods in molecular biology (1926). Humana Press: New York, NY, pp. 203-221. ISBN 9781493990207 (doi: 10.1007/978-1-4939-9021-4_17)
Dow, J. A.T. , Halberg, K. A., Terhzaz, S. and Davies, S. A. (2019) Drosophila as a model for neuroendocrine control of renal homeostasis. In: Ludwig, M. and Levkowitz, G. (eds.) Model Animals in Neuroendocrinology. Series: INF masterclass in neuroendocrinology series. Wiley: Hoboken, pp. 81-100. ISBN 9781119390947 (doi: 10.1002/9781119391128.ch4)
Petrie, J. R. and Salt, I. P. (2019) Diabetes and vascular disease. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 429-437. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_40)
Rezig, I. M., Bremner, S. K. , Bhutta, M. S., Salt, I. P. , Gould, G. W. and McInerny, C. J. (2019) Genetic and cytological methods to study ESCRT cell cycle function in fission yeast. In: Culetto, E. and Legouis, R. (eds.) The ESCRT Complexes: Methods and Protocols. Series: Methods in molecular biology (1998). Humana Press: New York, pp. 239-250. ISBN 9781493994915 (doi: 10.1007/978-1-4939-9492-2_18)
Simon, N. M.L., Litthauer, S., Jones, M. A. and Dodd, A. N. (2019) Interactions between circadian rhythms, ROS and redox. In: Panda, S. K. and Yamamoto, Y. Y. (eds.) Redox Homeostasis in Plants: From Signalling to Stress Tolerance. Series: Signaling and communication in plants. Springer: Cham, pp. 67-84. ISBN 9783319953144 (doi: 10.1007/978-3-319-95315-1_4)
Trujillo, S. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2019) Mechanotransduction and growth factor signaling in hydrogel-based microenvironments. In: Encyclopedia of Tissue Engineering and Regenerative Medicine. Elsevier, pp. 87-101. ISBN 9780128137000 (doi: 10.1016/B978-0-12-801238-3.11141-9)
Conference or Workshop Item
Thompson, K.J., Khajehali, E., Molloy, C. , Valant, C., Bradley, S.J. , Sexton, P.M., Christopoulos, A. and Tobin, A.B. (2019) The In Vitro Characterisation of DREADD Agonist 21, a Novel Ligand for Muscarinic DREADD Receptors. British Journal of Pharmacology 176(16): 3002-3003. Selected Abstract from Pharmacology 2018, London, UK, 18-20 Dec 2018. (doi: 10.1111/bph.14681)
Zhdanov, O. , Busse, A. , Cammarano, A. , Zare-Behtash, H. and Blatt, M. (2019) Effect of Wind on Morphology and Mechanical Properties of Arabidopsis Thaliana. SES 2019 – Society of Engineering Science, 56th Annual Technical Meeting, Washington University, St. Louis, 13-15 October 2019.
Conference Proceedings
Smith, C., Hosseini, E. S. , Riehle, M. , Hart, A. and Dahiya, R. (2019) Piezoelectric Plastic Compressed Collagen-mesh Scaffold for Artificial Skin. In: IEEE Sensors 2019, Montreal, QC, Canada, 27-30 Oct 2019, ISBN 9781728116341 (doi: 10.1109/SENSORS43011.2019.8956582)