Dr Stephen McSorley
- Senior Clinical Research Fellow (School of Cancer Sciences)
- Honorary Clinical Lecturer (School of Medicine, Dentistry & Nursing)
email:
Stephen.McSorley@glasgow.ac.uk
School of Medicine, Dentistry & Nursing, Level 2, New Lister Building, Glasgow Royal Infirmary, Glasgow, G31 2ER
Biography
Stephen is currently a Senior Clinical Lecturer and Honorary Consultant Colorectal Surgeon based at the University of Glasgow. He qualified from the University of Glasgow Medical School in 2009, and undertook his foundation, core and higher surgical training in the West of Scotland. He completed his PhD in colorectal cancer surgery at the University of Glasgow and Glasgow Royal Infirmary in 2019 and was awarded Fellowship of the Royal College of Physicians and Surgeons of Glasgow in 2021. Prior to his current appointment he undertook a Royal College of Surgeons Senior Clinical Fellowship in minimally invasive colorectal cancer surgery. His research interests include the influence of the postoperative systemic inflammatory response on morbidity and long-term survival after surgery for colorectal cancer and the early detection and prevention of colorectal cancer in symptomatic and screened populations.
Research interests
Research groups
- Cancer Evolution in Time & Space
- Immunology & Cancer
- Health Inequalities to Cancer Outcomes
Publications
2024
Brown, L. R. et al. (2024) Cachexia index for prognostication in surgical patients with locally advanced oesophageal or gastric cancer: multicentre cohort study. British Journal of Surgery, 111(4), znae098. (doi: 10.1093/bjs/znae098) (PMID:38593042) (PMCID:PMC11003541)
Ingham,, A. R. et al. (2024) Robotic-assisted surgery for left sided colon and rectal resections is associated with reduction in the postoperative surgical stress response and improved short-term outcomes: a cohort study. Surgical Endoscopy, (doi: 10.1007/s00464-024-10749-3) (PMID:38498212)
Johnstone, M. S., McSorley, S. T. , McMillan, D. C. , Horgan, P. G. and Mansouri, D. (2024) The relationship between systemic inflammatory response, screen detection and outcome in colorectal cancer. Colorectal Disease, 26(1), pp. 81-94. (doi: 10.1111/codi.16824) (PMID:38095280)
2023
Johnstone, M. S., McSorley, S. T. and McMahon, A. J. (2023) Management of malignant T1 colorectal cancer polyps: results from a 10-year prospective observational study. Colorectal Disease, 25(10), pp. 1960-1972. (doi: 10.1111/codi.16716) (PMID:37612791)
Johnstone, M. S., Stoops, R., Lynch, G., Hay, J., Jawny, J., Sloan, W., Edwards, J. and McSorley, S. T. (2023) Risk stratification for the detection of metachronous polyps after bowel screening polypectomy: clinical outcomes from the Integrated Technologies for Improved Polyp Surveillance (INCISE) study cohort. BJS Open, 7(3), zrad034. (doi: 10.1093/bjsopen/zrad034) (PMID:37158435) (PMCID:PMC10167706)
McGovern, J. et al. (2023) The relationship between computed tomography-derived sarcopenia, cardiopulmonary exercise testing performance, systemic inflammation, and survival in good performance status patients with oesophago-gastric cancer undergoing neoadjuvant treatment. JCSM Clinical Reports, 8(1), pp. 3-11. (doi: 10.1002/crt2.57)
2022
Johnstone, M. S., MacLeod, C., Digby, J., Al-Azzawi, Y., Pang, G., Watson, A. J.M., Strachan, J., Mowat, C. and McSorley, S. T. (2022) Prevalence of repeat faecal immunochemical testing in symptomatic patients attending primary care. Colorectal Disease, 24(12), pp. 1498-1504. (doi: 10.1111/codi.16240) (PMID:35776684)
Johnstone, M. S. et al. (2022) Alternative diagnoses and demographics associated with a raised quantitative faecal immunochemical test in symptomatic patients. Annals of Clinical Biochemistry, 59(4), pp. 277-287. (doi: 10.1177/00045632221076771) (PMID:35044264) (PMCID:PMC9280700)
Johnstone, M. S., Burton, P., Kourounis, G. , Winter, J., Crighton, E., Mansouri, D. , Witherspoon, P., Smith, K. and McSorley, S. T. (2022) Combining the quantitative faecal immunochemical test and full blood count reliably rules out colorectal cancer in a symptomatic patient referral pathway. International Journal of Colorectal Disease, 37(2), pp. 457-466. (doi: 10.1007/s00384-021-04079-2) (PMID:34932152) (PMCID:PMC8803704)
2021
van Winsen, M., McSorley, S. T. , McLeod, R., MacDonald, A., Forshaw, M. J., Shaw, M. and Puxty, K. (2021) Postoperative C-reactive protein concentrations to predict infective complications following gastrectomy for cancer. Journal of Surgical Oncology, 124(7), pp. 1060-1069. (doi: 10.1002/jso.26613) (PMID:34350587)
Chan, B. Y.L., McKinlay, S., Forshaw, M., Macdonald, A., Maitra, R., Orizu, M. and McSorley, S. T. (2021) Impact of anaemia in oesophago-gastric cancer patients undergoing curative treatment by means of neoadjuvant chemotherapy and surgery. Surgical Oncology, 38, 101585. (doi: 10.1016/j.suronc.2021.101585) (PMID:33930843)
Johnstone, M. S., Lynch, G., Park, J. , McSorley, S. and Edwards, J. (2021) Novel methods of risk stratifying patients for metachronous, pre-malignant colorectal polyps: a systematic review. Critical Reviews in Oncology/Haematology, 164, 103421. (doi: 10.1016/j.critrevonc.2021.103421) (PMID:34246774)
Mansouri, D. , McSorley, S. T. , Park, J. H. , Orange, C., Horgan, P. G. , McMillan, D. C. and Edwards, J. (2021) The inflammatory microenvironment in screen-detected premaligant adenomatous polyps: early results from the integrated technologies for improved polyp surveillance (INCISE) project. European Journal of Gastroenterology and Hepatology, 33(7), pp. 983-989. (doi: 10.1097/MEG.0000000000002202) (PMID:34034277)
McSorley, S. T. et al. (2021) Yield of colorectal cancer at colonoscopy according to faecal haemoglobin concentration in symptomatic patients referred from primary care. Colorectal Disease, 23(7), pp. 1615-1621. (doi: 10.1111/codi.15405) (PMID:33064898)
McSorley, S. T. , Lau, H. Y.N., McIntosh, D., Forshaw, M. J., McMillan, D. C. and Crumley, A. B. (2021) Staging the tumour and staging the host: Pre-treatment combined Neutrophil Lymphocyte Ratio and modified Glasgow Prognostic Score is associated with overall survival in patients with oesophagogastric cancers undergoing treatment with curative intent. Annals of Surgical Oncology, 28(2), pp. 722-731. (doi: 10.1245/s10434-020-09074-5) (PMID:32892266) (PMCID:PMC7801291)
McSorley, S. T. , Steele, C. W. , Anderson, J. H. and McKinlay, S. (2021) Comment on 'Preoperative intravenous iron therapy and survival after colorectal cancer surgery: long term results from the IVICA randomised controlled trial'. Colorectal Disease, 23(2), pp. 555-556. (doi: 10.1111/codi.15428) (PMID:33159348)
Alhayyan, A. M. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2021) The effect of anesthesia on the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colorectal cancer in the context of an enhanced recovery pathway: A prospective cohort study. Medicine, 100(2), e23997. (doi: 10.1097/MD.0000000000023997) (PMID:33466141) (PMCID:PMC7808526)
2020
Dolan, R. D. , Maclay, J. D., Abbass, T., Colville, D., Buali, F., MacLeod, N., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2020) The relationship between 18F-FDG-PETCT-derived tumour metabolic activity, nutritional risk, body composition, systemic inflammation and survival in patients with lung cancer. Scientific Reports, 10, 20819. (doi: 10.1038/s41598-020-77269-7) (PMID:33257741) (PMCID:PMC7705735)
Dolan, R. D. , Alwahid, M., McSorley, S. T. , Park, J. H. , Stevenson, R. P., Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2020) A comparison of the prognostic value of composite ratios and cumulative scores in patients with operable rectal cancer. Scientific Reports, 10, 17965. (doi: 10.1038/s41598-020-73909-0) (PMID:33087753) (PMCID:PMC7578034)
Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2020) Authors' reply: Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short-term outcomes following left-sided colonic and rectal resections. BJS Open, 4(4), pp. 730-731. (doi: 10.1002/bjs5.50286) (PMID:32297454) (PMCID:PMC7397349)
McSorley, S. T. , Anderson, J. H., Whittle, T., Roxburgh, C. S. , Horgan, P. G. , McMillan, D. C. and Steele, C. W. (2020) The impact of preoperative systemic inflammation on the efficacy of intravenous iron infusion to correct anaemia prior to surgery for colorectal cancer. Perioperative Medicine, 9, 17. (doi: 10.1186/s13741-020-00146-4) (PMID:32537137) (PMCID:PMC7288411)
ALHAYYAN, A. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2020) The relationship between anaesthetic technique, clinicopathological characteristics and the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colon cancer. PLoS ONE, 15(4), e0228580. (doi: 10.1371/journal.pone.0228580) (PMID:32348308) (PMCID:PMC7190171)
Alhayyan, A. , McSorley, S. , Roxburgh, C. , Kearns, R. , Horgan, P. and McMillan, D. (2020) The effect of anesthesia on the postoperative systemic inflammatory response in patients undergoing surgery: a systematic review and meta-analysis. Surgery Open Science, 2(1), pp. 1-21. (doi: 10.1016/j.sopen.2019.06.001) (PMID:32754703) (PMCID:PMC7391900)
McSorley, S. T. , Tham, A., Dolan, R. D. , Steele, C. W. , Ramsingh, J., Roxburgh, C. , Horgan, P. G. and McMillan, D. C. (2020) Perioperative blood transfusion is associated with the postoperative systemic inflammatory response and poorer outcomes following surgery for colorectal cancer. Annals of Surgical Oncology, 27, pp. 833-843. (doi: 10.1245/s10434-019-07984-7) (PMID:31664621) (PMCID:PMC7000540)
2019
Almasaudi, A. S., McSorley, S. T. , Dolan, R. D. , Edwards, C. A. and McMillan, D. C. (2019) The relation between Malnutrition Universal Screening Tool (MUST), computed tomography-derived body composition, systemic inflammation, and clinical outcomes in patients undergoing surgery for colorectal cancer. American Journal of Clinical Nutrition, 110(6), pp. 1327-1334. (doi: 10.1093/ajcn/nqz230) (PMID:31529042)
Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2019) Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short‐term outcomes following left‐sided colonic and rectal resections. BJS Open, 3(6), pp. 830-839. (doi: 10.1002/bjs5.50224) (PMID:31832590) (PMCID:PMC6887908)
Golder, A. M. , McSorley, S. T. , Kearns, R. J. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S. (2019) Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: a qualitative study. Annals of Medicine and Surgery, 48, pp. 23-28. (doi: 10.1016/j.amsu.2019.10.007) (PMID:31687135) (PMCID:PMC6820077)
Almasaudi, A. S., Dolan, R. D. , McSorley, S. T. , Horgan, P. G. , Edwards, C. and McMillan, D. C. (2019) Relationship between computed tomography-derived body composition, sex, and post-operative complications in patients with colorectal cancer. European Journal of Clinical Nutrition, 73(11), pp. 1450-1457. (doi: 10.1038/s41430-019-0414-0) (PMID:30858540)
McSorley, S. T. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. , MacKay, G. J. and McMillan, D. C. (2019) Possible dose dependent effect of perioperative dexamethasone and laparoscopic surgery on the postoperative systemic inflammatory response and complications following surgery for colon cancer. European Journal of Surgical Oncology, 45(9), pp. 1613-1618. (doi: 10.1016/j.ejso.2019.05.020) (PMID:31130339)
McSorley, S. T. , Tham, A., Steele, C. W. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2019) Quantitative data on red cell measures of iron status and their relation to the magnitude of the systemic inflammatory response and survival in patients with colorectal cancer. European Journal of Surgical Oncology, 45(7), pp. 1205-1211. (doi: 10.1016/j.ejso.2019.02.027) (PMID:30850153)
Roseweir, A. K. , Clark, J., McSorley, S. T. , vanWyk, H. C. , Quinn, J. A. , Horgan, P. G. , McMillan, D. C. , Park, J. H. and Edwards, J. (2019) The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer. International Journal of Cancer, 144(9), pp. 2320-2329. (doi: 10.1002/ijc.32045) (PMID:30521130)
McSorley, S. T. , Tham, A., Jones, I., Talwar, D. and McMillan, D. C. (2019) Regression correction equation to adjust serum iron and ferritin concentrations based on C-reactive protein and albumin in patients receiving primary and secondary care. Journal of Nutrition, 149(5), pp. 877-883. (doi: 10.1093/jn/nxz008) (PMID:31050746)
Dolan, R. D. , McLees, N. G., Irfan, A., McSorley, S. T. , Horgan, P. G. , Colville, D. and McMillan, D. C. (2019) The relationship between tumour glucose metabolism and host systemic inflammatory responses in patients with cancer: a systematic review. Journal of Nuclear Medicine, 60(4), pp. 467-471. (doi: 10.2967/jnumed.118.216697) (PMID:30166353)
Almasaudi, A. S., McSorley, S. T. , Horgan, P. G. , McMillan, D. C. and Edwards, C. A. (2019) The relationship between body mass index, sex, and postoperative outcomes in patients undergoing potentially curative surgery for colorectal cancer. Clinical Nutrition ESPEN, 30, pp. 185-189. (doi: 10.1016/j.clnesp.2018.12.084) (PMID:30904219)
McSorley, S. , Johnstone, M., Steele, C. W. , Roxburgh, C. S.D. , Horgan, P. G. , McMillan, D. C. and Mansouri, D. (2019) Normocytic anaemia is associated with systemic inflammation and poorer survival in patients with colorectal cancer treated with curative intent. International Journal of Colorectal Disease, 34(3), pp. 401-408. (doi: 10.1007/s00384-018-3211-7) (PMID:30515556)
Dolan, R. , Almasaudi, A. S., Dieu, L. B., Horgan, P. G. , McSorley, S. T. and McMillan, D. C. (2019) The relationship between computed tomography‐derived body composition, systemic inflammatory response, and survival in patients undergoing surgery for colorectal cancer. Journal of Cachexia, Sarcopenia and Muscle, 10(1), pp. 111-122. (doi: 10.1002/jcsm.12357) (PMID:30460764) (PMCID:PMC6438413)
2018
Park, J. H. et al. (2018) Staging the tumor and staging the host: A two centre, two country comparison of systemic inflammatory responses of patients undergoing resection of primary operable colorectal cancer. American Journal of Surgery, 216(3), pp. 458-464. (doi: 10.1016/j.amjsurg.2017.08.044) (PMID:28967380)
McSorley, S.T. , Steele, C.W. and McMahon, A.J. (2018) Meta‐analysis of oral antibiotics, in combination with preoperative intravenous antibiotics and mechanical bowel preparation the day before surgery, compared with intravenous antibiotics and mechanical bowel preparation alone to reduce surgical‐site infections in elective colorectal surgery. BJS Open, 2(4), pp. 185-194. (doi: 10.1002/bjs5.68) (PMID:30079387) (PMCID:PMC6069350)
McSorley, S. T. , Black, D. H., Horgan, P. G. and McMillan, D. C. (2018) The relationship between tumour stage, systemic inflammation, body composition and survival in patients with colorectal cancer. Clinical Nutrition, 37(4), pp. 1279-1285. (doi: 10.1016/j.clnu.2017.05.017) (PMID:28566220)
Dolan, R. D. , McSorley, S. T. , Park, J. H. , Watt, D. G. , Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2018) The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores. British Journal of Cancer, 119(1), pp. 40-51. (doi: 10.1038/s41416-018-0095-9) (PMID:29789606)
McSorley, S. T. , Talwar, D. and McMillan, D. C. (2018) Comment on the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project. American Journal of Clinical Nutrition, 108(1), pp. 204-205. (doi: 10.1093/ajcn/nqx071) (PMID:29982308)
McSorley, S. T. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2018) The relationship between cardiopulmonary exercise test variables, the systemic inflammatory response, and complications following surgery for colorectal cancer. Perioperative Medicine, 7(1), 11. (doi: 10.1186/s13741-018-0093-8) (PMID:29983927) (PMCID:PMC6003031)
McSorley, S. T. , Khor, B. Y., Tsang, K., Colville, D., Han, S., Horgan, P. G. and McMillan, D. C. (2018) The relationship between 18F FDG-PETCT derived markers of tumour metabolism and systemic inflammation in patients with recurrent disease following surgery for colorectal cancer. Colorectal Disease, 20(5), pp. 407-415. (doi: 10.1111/codi.13973)
Dolan, R. , McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2018) Determinants of lymph node count and positivity in patients undergoing surgery for colon cancer. Medicine, 97(13), e0185. (doi: 10.1097/MD.0000000000010185) (PMID:29595652) (PMCID:29595652)
McSorley, S. T. , Mansouri, D. , Horgan, P. G. and McMillan, D. C. (2018) Comment on "the important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial". Annals of Surgery, 267(3), e49. (doi: 10.1097/SLA.0000000000002053) (PMID:27759622)
Patel, M., McSorley, S. T. , Park, J. H. , Roxburgh, C. S.D. , Edwards, J. , Horgan, P. G. and McMillan, D. C. (2018) The relationship between right-sided tumour location, tumour microenvironment, systemic inflammation, adjuvant therapy and survival in patients undergoing surgery for colon and rectal cancer. British Journal of Cancer, 118(5), pp. 705-712. (doi: 10.1038/bjc.2017.441) (PMID:29337962) (PMCID:PMC5846060)
Almasaudi, A. S., McSorley, S. T. , Edwards, C. A. and McMillan, D. C. (2018) The relationship between body mass index and short term postoperative outcomes in patients undergoing potentially curative surgery for colorectal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 121, pp. 68-73. (doi: 10.1016/j.critrevonc.2017.12.004) (PMID:29279101)
Dolan, R. , McSorley, S. T. , Park, J. H. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2018) The Prognostic Value of Systemic Inflammation in Patients Undergoing Surgery for Rectal Cancer: Comparison of Composite Ratios and Cumulative Scores. Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 18-20 Jan 2018. (doi: 10.1200/JCO.2018.36.4_suppl.579)
Dolan, R. , Tilling, E., Kong, C. Y. , MacLeod, N. J., McSorley, S. T. , Park, J. H. , Glen, P., Horgan, P. G. , Laird, B. and McMillan, D. C. (2018) Evaluation of Systemic Inflammation Based Prognostic Scores in Patients with Advanced Oesophageal Cancer Receiving Palliative Radiotherapy. Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 18-20 Jan 2018.
2017
Dolan, R. D. , Lim, J., Mcsorley, S. T. , Horgan, P. G. and McMillan, D. C. (2017) The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis. Scientific Reports, 7, 16717. (doi: 10.1038/s41598-017-16955-5) (PMID:29196718) (PMCID:PMC5711862)
Dolan, R. D. , McSorley, S. T. , McMillan, D. C. and Horgan, P. G. (2017) Attitudes of surgeons to the use of postoperative markers of the systemic inflammatory response following elective surgery. Annals of Medicine and Surgery, 21, pp. 14-19. (doi: 10.1016/j.amsu.2017.07.046) (PMID:28761641) (PMCID:PMC5524306)
Watt, D. G. , Ramanathan, M. L., McSorley, S. T. , Walley, K., Park, J. H. , Horgan, P. G. and McMillan, D. C. (2017) Clinicopathological determinants of an elevated systemic inflammatory response following elective potentially curative resection for colorectal cancer. Annals of Surgical Oncology, 24(9), pp. 2588-2594. (doi: 10.1245/s10434-017-5987-z) (PMID:28695389) (PMCID:PMC5539269)
Dolan, R. D. , McSorley, S. T. , Horgan, P. G. , Laird, B. and McMillan, D. C. (2017) The role of the systemic inflammatory response in predicting outcomes in patients with advanced inoperable cancer: Systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 116, pp. 134-146. (doi: 10.1016/j.critrevonc.2017.06.002) (PMID:28693795)
Mcsorley, S. T. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2017) The impact of preoperative dexamethasone on the magnitude of the postoperative systemic inflammatory response and complications following surgery for colorectal cancer. Annals of Surgical Oncology, 24(8), pp. 2104-2112. (doi: 10.1245/s10434-017-5817-3) (PMID:28251379)
Kelly, A. U., McSorley, S. T. , Patel, P. and Talwar, D. (2017) Interpreting iron studies. British Medical Journal, 357, j2513. (doi: 10.1136/bmj.j2513)
Dreyer, S. B., Powell, A. G.M.T., McSorley, S. T. , Waterston, A., Going, J. J., Edwards, J. , McMillan, D. C. and Horgan, P. G. (2017) The pretreatment systemic inflammatory response is an important determinant of poor pathologic response for patients undergoing neoadjuvant therapy for rectal cancer. Annals of Surgical Oncology, 24(5), pp. 1295-1303. (doi: 10.1245/s10434-016-5684-3) (PMID:27873100)
McSorley, S. T. , Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2017) Re: Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial). British Medical Journal, 357, j1455.
Watt, D., Mcsorley, S. T. , Park, J. H. , Horgan, P. G. and McMillan, D. C. (2017) A postoperative systemic inflammation score predicts short- and long-term outcomes in patients undergoing surgery for colorectal cancer. Annals of Surgical Oncology, 24(4), pp. 1100-1109. (doi: 10.1245/s10434-016-5659-4) (PMID:27822634)
Dolan, R. , MacLeod, N. J., McSorley, S. T. , Horgan, P. G. , Laird, B. and McMillan, D. C. (2017) Evaluation of Systemic Inflammation-based Prognostic Scores in Patients With Advanced Colorectal Cancer Receiving Palliative Pelvic Radiotherapy (RT). 2017 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 19-21 Jan 2017. (doi: 10.1200/jco.2017.35.4_suppl.558)
Dolan, R. , McSorley, S. T. , McMillan, D. C. and Horgan, P. G. (2017) Association of Ongoing Systemic Inflammatory Response (SIR) at Diagnosis With Lymph Node Retrieval and Node Positivity in Patients Undergoing Surgery for Colonic Cancer. 2017 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 19-21 Jan 2017. (doi: 10.1200/jco.2017.35.4_suppl.550)
Mcsorley, S. T. , Khor, B. Y., MacKJay, G. J., Horgan, P. G. and McMillan, D. C. (2017) Examination of a CRP first approach for the detection of postoperative complications in patients undergoing surgery for colorectal cancer: a pragmatic study. Medicine, 96(7), e6133. (doi: 10.1097/MD.0000000000006133) (PMID:28207541)
Khor, B. Y., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2017) The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: a cross-sectional study. International Journal of Surgery, 37, pp. 79-84. (doi: 10.1016/j.ijsu.2016.12.010) (PMID:27940290)
Dolan, R. , McLeod, N., McSorley, S. , McMillan, D. and Horgan, P. (2017) Evaluation of Systemic Inflammation Based Prognostic Scoresin Patients with Advanced Rectal Cancer Receiving Palliative Pelvicradiotherapy. International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Glasgow, UK, 03-05 May 2017.
Dolan, R. , McSorley, S. , McMillan, D. and Horgan, P. (2017) Ongoing Systemic Inflammatory Response at Diagnosis is Notassociated with Lower Lymph Node Retrieval and Higher Node Positivityin Patients Undergoing Surgery for Colonic Cancer. International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Glasgow, UK, 03-05 May 2017.
McSorley, S. T. , Dolan, R. D. , Roxburgh, C. S.D. , McMillan, D. C. and Horgan, P. G. (2017) How and why systemic inflammation worsens quality of life in patients with advanced cancer. Expert Review of Quality of Life in Cancer Care, 2(3), pp. 167-175. (doi: 10.1080/23809000.2017.1331705)
2016
Mcsorley, S. T. , Jones, I., McMillan, D. C. and Talwar, D. (2016) Quantitative data on the magnitude of the systemic inflammatory response and its relationship with serum measures of iron status. Translational Research, 176, pp. 119-126. (doi: 10.1016/j.trsl.2016.05.004) (PMID:27337525)
McSorley, S. T. , Watt, D. G., Horgan, P. G. and McMillan, D. C. (2016) Postoperative systemic inflammatory response, complication severity, and survival following surgery for colorectal cancer. Annals of Surgical Oncology, 23(9), pp. 2832-2840. (doi: 10.1245/s10434-016-5204-5) (PMID:27016295) (PMCID:PMC4972846)
McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2016) The impact of the type and severity of postoperative complications on long-term outcomes following surgery for colorectal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 97, pp. 168-177. (doi: 10.1016/j.critrevonc.2015.08.013) (PMID:26330375)
McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2016) The impact of preoperative corticosteroids on the systemic inflammatory response and postoperative complications following surgery for gastrointestinal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 101, pp. 139-150. (doi: 10.1016/j.critrevonc.2016.03.011) (PMID:26997303)
2015
Watt, D. G., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2015) Enhanced recovery after surgery. Medicine, 94(36), e1286. (doi: 10.1097/md.0000000000001286) (PMCID:PMC4616657)
McSorley, S. T. , Ramanathan, M., Horgan, P. and McMillan, D. (2015) Postoperative C-reactive protein measurement predicts the severity of complications following surgery for colorectal cancer. International Journal of Colorectal Disease, 30(7), pp. 913-917. (doi: 10.1007/s00384-015-2229-3) (PMID:25922147)
McSorley, S. T. , Ramanathan, M. L., Horgan, P. G. and McMillan, D. C. (2015) Mo1619 Postoperative C-reactive protein measurement predicts the severity of complications following surgery for colorectal cancer. Gastroenterology, 148(4), S-1152. (doi: 10.1016/S0016-5085(15)33932-9)
McSorley, S. T. , Watt, D. G., Horgan, P. G. and McMillan, D. C. (2015) 868 Complication type and severity have an adverse effect on long-term oncological outcome following surgery for colorectal cancer. Gastroenterology, 148(4), S-1122. (doi: 10.1016/S0016-5085(15)33823-3)
Watt, D. G., McSorley, S. T. , Park, J. H. , Horgan, P. G. and McMillan, D. C. (2015) 879 The validation of C-reactive protein and albumin as predictors of post-operative infective complications and their clinical utility in patients with colorectal cancer. Gastroenterology, 148(4), S-1125. (doi: 10.1016/S0016-5085(15)33834-8)
2014
McSorley, S.T. , Drury, M., Majumdar, P., Halsall, A. and Nalagatla, S. (2014) C-reactive protein to predict the need for surgical intervention in acute renal colic. Journal of Clinical Urology, 7(6), pp. 380-383. (doi: 10.1177/2051415813495679)
2013
McSorley, S. , Lowndes, C., Sharma, P. and Macdonald, A. (2013) Unplanned reoperation within 30 days of surgery for colorectal cancer in NHS Lanarkshire. Colorectal Disease, 15(6), pp. 689-694. (doi: 10.1111/codi.12135) (PMID:23398663)
McSorley, S. , Kochman, A. and DeSouza, J. (2013) Grand rounds: Müllerianosis of the urinary bladder in a postmenopausal woman. Urology, 81(3), pp. 488-490. (doi: 10.1016/j.urology.2012.11.013) (PMID:23312895)
Articles
Brown, L. R. et al. (2024) Cachexia index for prognostication in surgical patients with locally advanced oesophageal or gastric cancer: multicentre cohort study. British Journal of Surgery, 111(4), znae098. (doi: 10.1093/bjs/znae098) (PMID:38593042) (PMCID:PMC11003541)
Ingham,, A. R. et al. (2024) Robotic-assisted surgery for left sided colon and rectal resections is associated with reduction in the postoperative surgical stress response and improved short-term outcomes: a cohort study. Surgical Endoscopy, (doi: 10.1007/s00464-024-10749-3) (PMID:38498212)
Johnstone, M. S., McSorley, S. T. , McMillan, D. C. , Horgan, P. G. and Mansouri, D. (2024) The relationship between systemic inflammatory response, screen detection and outcome in colorectal cancer. Colorectal Disease, 26(1), pp. 81-94. (doi: 10.1111/codi.16824) (PMID:38095280)
Johnstone, M. S., McSorley, S. T. and McMahon, A. J. (2023) Management of malignant T1 colorectal cancer polyps: results from a 10-year prospective observational study. Colorectal Disease, 25(10), pp. 1960-1972. (doi: 10.1111/codi.16716) (PMID:37612791)
Johnstone, M. S., Stoops, R., Lynch, G., Hay, J., Jawny, J., Sloan, W., Edwards, J. and McSorley, S. T. (2023) Risk stratification for the detection of metachronous polyps after bowel screening polypectomy: clinical outcomes from the Integrated Technologies for Improved Polyp Surveillance (INCISE) study cohort. BJS Open, 7(3), zrad034. (doi: 10.1093/bjsopen/zrad034) (PMID:37158435) (PMCID:PMC10167706)
McGovern, J. et al. (2023) The relationship between computed tomography-derived sarcopenia, cardiopulmonary exercise testing performance, systemic inflammation, and survival in good performance status patients with oesophago-gastric cancer undergoing neoadjuvant treatment. JCSM Clinical Reports, 8(1), pp. 3-11. (doi: 10.1002/crt2.57)
Johnstone, M. S., MacLeod, C., Digby, J., Al-Azzawi, Y., Pang, G., Watson, A. J.M., Strachan, J., Mowat, C. and McSorley, S. T. (2022) Prevalence of repeat faecal immunochemical testing in symptomatic patients attending primary care. Colorectal Disease, 24(12), pp. 1498-1504. (doi: 10.1111/codi.16240) (PMID:35776684)
Johnstone, M. S. et al. (2022) Alternative diagnoses and demographics associated with a raised quantitative faecal immunochemical test in symptomatic patients. Annals of Clinical Biochemistry, 59(4), pp. 277-287. (doi: 10.1177/00045632221076771) (PMID:35044264) (PMCID:PMC9280700)
Johnstone, M. S., Burton, P., Kourounis, G. , Winter, J., Crighton, E., Mansouri, D. , Witherspoon, P., Smith, K. and McSorley, S. T. (2022) Combining the quantitative faecal immunochemical test and full blood count reliably rules out colorectal cancer in a symptomatic patient referral pathway. International Journal of Colorectal Disease, 37(2), pp. 457-466. (doi: 10.1007/s00384-021-04079-2) (PMID:34932152) (PMCID:PMC8803704)
van Winsen, M., McSorley, S. T. , McLeod, R., MacDonald, A., Forshaw, M. J., Shaw, M. and Puxty, K. (2021) Postoperative C-reactive protein concentrations to predict infective complications following gastrectomy for cancer. Journal of Surgical Oncology, 124(7), pp. 1060-1069. (doi: 10.1002/jso.26613) (PMID:34350587)
Chan, B. Y.L., McKinlay, S., Forshaw, M., Macdonald, A., Maitra, R., Orizu, M. and McSorley, S. T. (2021) Impact of anaemia in oesophago-gastric cancer patients undergoing curative treatment by means of neoadjuvant chemotherapy and surgery. Surgical Oncology, 38, 101585. (doi: 10.1016/j.suronc.2021.101585) (PMID:33930843)
Johnstone, M. S., Lynch, G., Park, J. , McSorley, S. and Edwards, J. (2021) Novel methods of risk stratifying patients for metachronous, pre-malignant colorectal polyps: a systematic review. Critical Reviews in Oncology/Haematology, 164, 103421. (doi: 10.1016/j.critrevonc.2021.103421) (PMID:34246774)
Mansouri, D. , McSorley, S. T. , Park, J. H. , Orange, C., Horgan, P. G. , McMillan, D. C. and Edwards, J. (2021) The inflammatory microenvironment in screen-detected premaligant adenomatous polyps: early results from the integrated technologies for improved polyp surveillance (INCISE) project. European Journal of Gastroenterology and Hepatology, 33(7), pp. 983-989. (doi: 10.1097/MEG.0000000000002202) (PMID:34034277)
McSorley, S. T. et al. (2021) Yield of colorectal cancer at colonoscopy according to faecal haemoglobin concentration in symptomatic patients referred from primary care. Colorectal Disease, 23(7), pp. 1615-1621. (doi: 10.1111/codi.15405) (PMID:33064898)
McSorley, S. T. , Lau, H. Y.N., McIntosh, D., Forshaw, M. J., McMillan, D. C. and Crumley, A. B. (2021) Staging the tumour and staging the host: Pre-treatment combined Neutrophil Lymphocyte Ratio and modified Glasgow Prognostic Score is associated with overall survival in patients with oesophagogastric cancers undergoing treatment with curative intent. Annals of Surgical Oncology, 28(2), pp. 722-731. (doi: 10.1245/s10434-020-09074-5) (PMID:32892266) (PMCID:PMC7801291)
McSorley, S. T. , Steele, C. W. , Anderson, J. H. and McKinlay, S. (2021) Comment on 'Preoperative intravenous iron therapy and survival after colorectal cancer surgery: long term results from the IVICA randomised controlled trial'. Colorectal Disease, 23(2), pp. 555-556. (doi: 10.1111/codi.15428) (PMID:33159348)
Alhayyan, A. M. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2021) The effect of anesthesia on the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colorectal cancer in the context of an enhanced recovery pathway: A prospective cohort study. Medicine, 100(2), e23997. (doi: 10.1097/MD.0000000000023997) (PMID:33466141) (PMCID:PMC7808526)
Dolan, R. D. , Maclay, J. D., Abbass, T., Colville, D., Buali, F., MacLeod, N., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2020) The relationship between 18F-FDG-PETCT-derived tumour metabolic activity, nutritional risk, body composition, systemic inflammation and survival in patients with lung cancer. Scientific Reports, 10, 20819. (doi: 10.1038/s41598-020-77269-7) (PMID:33257741) (PMCID:PMC7705735)
Dolan, R. D. , Alwahid, M., McSorley, S. T. , Park, J. H. , Stevenson, R. P., Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2020) A comparison of the prognostic value of composite ratios and cumulative scores in patients with operable rectal cancer. Scientific Reports, 10, 17965. (doi: 10.1038/s41598-020-73909-0) (PMID:33087753) (PMCID:PMC7578034)
Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2020) Authors' reply: Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short-term outcomes following left-sided colonic and rectal resections. BJS Open, 4(4), pp. 730-731. (doi: 10.1002/bjs5.50286) (PMID:32297454) (PMCID:PMC7397349)
McSorley, S. T. , Anderson, J. H., Whittle, T., Roxburgh, C. S. , Horgan, P. G. , McMillan, D. C. and Steele, C. W. (2020) The impact of preoperative systemic inflammation on the efficacy of intravenous iron infusion to correct anaemia prior to surgery for colorectal cancer. Perioperative Medicine, 9, 17. (doi: 10.1186/s13741-020-00146-4) (PMID:32537137) (PMCID:PMC7288411)
ALHAYYAN, A. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2020) The relationship between anaesthetic technique, clinicopathological characteristics and the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colon cancer. PLoS ONE, 15(4), e0228580. (doi: 10.1371/journal.pone.0228580) (PMID:32348308) (PMCID:PMC7190171)
Alhayyan, A. , McSorley, S. , Roxburgh, C. , Kearns, R. , Horgan, P. and McMillan, D. (2020) The effect of anesthesia on the postoperative systemic inflammatory response in patients undergoing surgery: a systematic review and meta-analysis. Surgery Open Science, 2(1), pp. 1-21. (doi: 10.1016/j.sopen.2019.06.001) (PMID:32754703) (PMCID:PMC7391900)
McSorley, S. T. , Tham, A., Dolan, R. D. , Steele, C. W. , Ramsingh, J., Roxburgh, C. , Horgan, P. G. and McMillan, D. C. (2020) Perioperative blood transfusion is associated with the postoperative systemic inflammatory response and poorer outcomes following surgery for colorectal cancer. Annals of Surgical Oncology, 27, pp. 833-843. (doi: 10.1245/s10434-019-07984-7) (PMID:31664621) (PMCID:PMC7000540)
Almasaudi, A. S., McSorley, S. T. , Dolan, R. D. , Edwards, C. A. and McMillan, D. C. (2019) The relation between Malnutrition Universal Screening Tool (MUST), computed tomography-derived body composition, systemic inflammation, and clinical outcomes in patients undergoing surgery for colorectal cancer. American Journal of Clinical Nutrition, 110(6), pp. 1327-1334. (doi: 10.1093/ajcn/nqz230) (PMID:31529042)
Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2019) Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short‐term outcomes following left‐sided colonic and rectal resections. BJS Open, 3(6), pp. 830-839. (doi: 10.1002/bjs5.50224) (PMID:31832590) (PMCID:PMC6887908)
Golder, A. M. , McSorley, S. T. , Kearns, R. J. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S. (2019) Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: a qualitative study. Annals of Medicine and Surgery, 48, pp. 23-28. (doi: 10.1016/j.amsu.2019.10.007) (PMID:31687135) (PMCID:PMC6820077)
Almasaudi, A. S., Dolan, R. D. , McSorley, S. T. , Horgan, P. G. , Edwards, C. and McMillan, D. C. (2019) Relationship between computed tomography-derived body composition, sex, and post-operative complications in patients with colorectal cancer. European Journal of Clinical Nutrition, 73(11), pp. 1450-1457. (doi: 10.1038/s41430-019-0414-0) (PMID:30858540)
McSorley, S. T. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. , MacKay, G. J. and McMillan, D. C. (2019) Possible dose dependent effect of perioperative dexamethasone and laparoscopic surgery on the postoperative systemic inflammatory response and complications following surgery for colon cancer. European Journal of Surgical Oncology, 45(9), pp. 1613-1618. (doi: 10.1016/j.ejso.2019.05.020) (PMID:31130339)
McSorley, S. T. , Tham, A., Steele, C. W. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2019) Quantitative data on red cell measures of iron status and their relation to the magnitude of the systemic inflammatory response and survival in patients with colorectal cancer. European Journal of Surgical Oncology, 45(7), pp. 1205-1211. (doi: 10.1016/j.ejso.2019.02.027) (PMID:30850153)
Roseweir, A. K. , Clark, J., McSorley, S. T. , vanWyk, H. C. , Quinn, J. A. , Horgan, P. G. , McMillan, D. C. , Park, J. H. and Edwards, J. (2019) The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer. International Journal of Cancer, 144(9), pp. 2320-2329. (doi: 10.1002/ijc.32045) (PMID:30521130)
McSorley, S. T. , Tham, A., Jones, I., Talwar, D. and McMillan, D. C. (2019) Regression correction equation to adjust serum iron and ferritin concentrations based on C-reactive protein and albumin in patients receiving primary and secondary care. Journal of Nutrition, 149(5), pp. 877-883. (doi: 10.1093/jn/nxz008) (PMID:31050746)
Dolan, R. D. , McLees, N. G., Irfan, A., McSorley, S. T. , Horgan, P. G. , Colville, D. and McMillan, D. C. (2019) The relationship between tumour glucose metabolism and host systemic inflammatory responses in patients with cancer: a systematic review. Journal of Nuclear Medicine, 60(4), pp. 467-471. (doi: 10.2967/jnumed.118.216697) (PMID:30166353)
Almasaudi, A. S., McSorley, S. T. , Horgan, P. G. , McMillan, D. C. and Edwards, C. A. (2019) The relationship between body mass index, sex, and postoperative outcomes in patients undergoing potentially curative surgery for colorectal cancer. Clinical Nutrition ESPEN, 30, pp. 185-189. (doi: 10.1016/j.clnesp.2018.12.084) (PMID:30904219)
McSorley, S. , Johnstone, M., Steele, C. W. , Roxburgh, C. S.D. , Horgan, P. G. , McMillan, D. C. and Mansouri, D. (2019) Normocytic anaemia is associated with systemic inflammation and poorer survival in patients with colorectal cancer treated with curative intent. International Journal of Colorectal Disease, 34(3), pp. 401-408. (doi: 10.1007/s00384-018-3211-7) (PMID:30515556)
Dolan, R. , Almasaudi, A. S., Dieu, L. B., Horgan, P. G. , McSorley, S. T. and McMillan, D. C. (2019) The relationship between computed tomography‐derived body composition, systemic inflammatory response, and survival in patients undergoing surgery for colorectal cancer. Journal of Cachexia, Sarcopenia and Muscle, 10(1), pp. 111-122. (doi: 10.1002/jcsm.12357) (PMID:30460764) (PMCID:PMC6438413)
Park, J. H. et al. (2018) Staging the tumor and staging the host: A two centre, two country comparison of systemic inflammatory responses of patients undergoing resection of primary operable colorectal cancer. American Journal of Surgery, 216(3), pp. 458-464. (doi: 10.1016/j.amjsurg.2017.08.044) (PMID:28967380)
McSorley, S.T. , Steele, C.W. and McMahon, A.J. (2018) Meta‐analysis of oral antibiotics, in combination with preoperative intravenous antibiotics and mechanical bowel preparation the day before surgery, compared with intravenous antibiotics and mechanical bowel preparation alone to reduce surgical‐site infections in elective colorectal surgery. BJS Open, 2(4), pp. 185-194. (doi: 10.1002/bjs5.68) (PMID:30079387) (PMCID:PMC6069350)
McSorley, S. T. , Black, D. H., Horgan, P. G. and McMillan, D. C. (2018) The relationship between tumour stage, systemic inflammation, body composition and survival in patients with colorectal cancer. Clinical Nutrition, 37(4), pp. 1279-1285. (doi: 10.1016/j.clnu.2017.05.017) (PMID:28566220)
Dolan, R. D. , McSorley, S. T. , Park, J. H. , Watt, D. G. , Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2018) The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores. British Journal of Cancer, 119(1), pp. 40-51. (doi: 10.1038/s41416-018-0095-9) (PMID:29789606)
McSorley, S. T. , Talwar, D. and McMillan, D. C. (2018) Comment on the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project. American Journal of Clinical Nutrition, 108(1), pp. 204-205. (doi: 10.1093/ajcn/nqx071) (PMID:29982308)
McSorley, S. T. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2018) The relationship between cardiopulmonary exercise test variables, the systemic inflammatory response, and complications following surgery for colorectal cancer. Perioperative Medicine, 7(1), 11. (doi: 10.1186/s13741-018-0093-8) (PMID:29983927) (PMCID:PMC6003031)
McSorley, S. T. , Khor, B. Y., Tsang, K., Colville, D., Han, S., Horgan, P. G. and McMillan, D. C. (2018) The relationship between 18F FDG-PETCT derived markers of tumour metabolism and systemic inflammation in patients with recurrent disease following surgery for colorectal cancer. Colorectal Disease, 20(5), pp. 407-415. (doi: 10.1111/codi.13973)
Dolan, R. , McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2018) Determinants of lymph node count and positivity in patients undergoing surgery for colon cancer. Medicine, 97(13), e0185. (doi: 10.1097/MD.0000000000010185) (PMID:29595652) (PMCID:29595652)
McSorley, S. T. , Mansouri, D. , Horgan, P. G. and McMillan, D. C. (2018) Comment on "the important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial". Annals of Surgery, 267(3), e49. (doi: 10.1097/SLA.0000000000002053) (PMID:27759622)
Patel, M., McSorley, S. T. , Park, J. H. , Roxburgh, C. S.D. , Edwards, J. , Horgan, P. G. and McMillan, D. C. (2018) The relationship between right-sided tumour location, tumour microenvironment, systemic inflammation, adjuvant therapy and survival in patients undergoing surgery for colon and rectal cancer. British Journal of Cancer, 118(5), pp. 705-712. (doi: 10.1038/bjc.2017.441) (PMID:29337962) (PMCID:PMC5846060)
Almasaudi, A. S., McSorley, S. T. , Edwards, C. A. and McMillan, D. C. (2018) The relationship between body mass index and short term postoperative outcomes in patients undergoing potentially curative surgery for colorectal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 121, pp. 68-73. (doi: 10.1016/j.critrevonc.2017.12.004) (PMID:29279101)
Dolan, R. D. , Lim, J., Mcsorley, S. T. , Horgan, P. G. and McMillan, D. C. (2017) The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis. Scientific Reports, 7, 16717. (doi: 10.1038/s41598-017-16955-5) (PMID:29196718) (PMCID:PMC5711862)
Dolan, R. D. , McSorley, S. T. , McMillan, D. C. and Horgan, P. G. (2017) Attitudes of surgeons to the use of postoperative markers of the systemic inflammatory response following elective surgery. Annals of Medicine and Surgery, 21, pp. 14-19. (doi: 10.1016/j.amsu.2017.07.046) (PMID:28761641) (PMCID:PMC5524306)
Watt, D. G. , Ramanathan, M. L., McSorley, S. T. , Walley, K., Park, J. H. , Horgan, P. G. and McMillan, D. C. (2017) Clinicopathological determinants of an elevated systemic inflammatory response following elective potentially curative resection for colorectal cancer. Annals of Surgical Oncology, 24(9), pp. 2588-2594. (doi: 10.1245/s10434-017-5987-z) (PMID:28695389) (PMCID:PMC5539269)
Dolan, R. D. , McSorley, S. T. , Horgan, P. G. , Laird, B. and McMillan, D. C. (2017) The role of the systemic inflammatory response in predicting outcomes in patients with advanced inoperable cancer: Systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 116, pp. 134-146. (doi: 10.1016/j.critrevonc.2017.06.002) (PMID:28693795)
Mcsorley, S. T. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2017) The impact of preoperative dexamethasone on the magnitude of the postoperative systemic inflammatory response and complications following surgery for colorectal cancer. Annals of Surgical Oncology, 24(8), pp. 2104-2112. (doi: 10.1245/s10434-017-5817-3) (PMID:28251379)
Kelly, A. U., McSorley, S. T. , Patel, P. and Talwar, D. (2017) Interpreting iron studies. British Medical Journal, 357, j2513. (doi: 10.1136/bmj.j2513)
Dreyer, S. B., Powell, A. G.M.T., McSorley, S. T. , Waterston, A., Going, J. J., Edwards, J. , McMillan, D. C. and Horgan, P. G. (2017) The pretreatment systemic inflammatory response is an important determinant of poor pathologic response for patients undergoing neoadjuvant therapy for rectal cancer. Annals of Surgical Oncology, 24(5), pp. 1295-1303. (doi: 10.1245/s10434-016-5684-3) (PMID:27873100)
McSorley, S. T. , Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2017) Re: Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial). British Medical Journal, 357, j1455.
Watt, D., Mcsorley, S. T. , Park, J. H. , Horgan, P. G. and McMillan, D. C. (2017) A postoperative systemic inflammation score predicts short- and long-term outcomes in patients undergoing surgery for colorectal cancer. Annals of Surgical Oncology, 24(4), pp. 1100-1109. (doi: 10.1245/s10434-016-5659-4) (PMID:27822634)
Mcsorley, S. T. , Khor, B. Y., MacKJay, G. J., Horgan, P. G. and McMillan, D. C. (2017) Examination of a CRP first approach for the detection of postoperative complications in patients undergoing surgery for colorectal cancer: a pragmatic study. Medicine, 96(7), e6133. (doi: 10.1097/MD.0000000000006133) (PMID:28207541)
Khor, B. Y., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2017) The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: a cross-sectional study. International Journal of Surgery, 37, pp. 79-84. (doi: 10.1016/j.ijsu.2016.12.010) (PMID:27940290)
McSorley, S. T. , Dolan, R. D. , Roxburgh, C. S.D. , McMillan, D. C. and Horgan, P. G. (2017) How and why systemic inflammation worsens quality of life in patients with advanced cancer. Expert Review of Quality of Life in Cancer Care, 2(3), pp. 167-175. (doi: 10.1080/23809000.2017.1331705)
Mcsorley, S. T. , Jones, I., McMillan, D. C. and Talwar, D. (2016) Quantitative data on the magnitude of the systemic inflammatory response and its relationship with serum measures of iron status. Translational Research, 176, pp. 119-126. (doi: 10.1016/j.trsl.2016.05.004) (PMID:27337525)
McSorley, S. T. , Watt, D. G., Horgan, P. G. and McMillan, D. C. (2016) Postoperative systemic inflammatory response, complication severity, and survival following surgery for colorectal cancer. Annals of Surgical Oncology, 23(9), pp. 2832-2840. (doi: 10.1245/s10434-016-5204-5) (PMID:27016295) (PMCID:PMC4972846)
McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2016) The impact of the type and severity of postoperative complications on long-term outcomes following surgery for colorectal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 97, pp. 168-177. (doi: 10.1016/j.critrevonc.2015.08.013) (PMID:26330375)
McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2016) The impact of preoperative corticosteroids on the systemic inflammatory response and postoperative complications following surgery for gastrointestinal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 101, pp. 139-150. (doi: 10.1016/j.critrevonc.2016.03.011) (PMID:26997303)
Watt, D. G., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2015) Enhanced recovery after surgery. Medicine, 94(36), e1286. (doi: 10.1097/md.0000000000001286) (PMCID:PMC4616657)
McSorley, S. T. , Ramanathan, M., Horgan, P. and McMillan, D. (2015) Postoperative C-reactive protein measurement predicts the severity of complications following surgery for colorectal cancer. International Journal of Colorectal Disease, 30(7), pp. 913-917. (doi: 10.1007/s00384-015-2229-3) (PMID:25922147)
McSorley, S. T. , Ramanathan, M. L., Horgan, P. G. and McMillan, D. C. (2015) Mo1619 Postoperative C-reactive protein measurement predicts the severity of complications following surgery for colorectal cancer. Gastroenterology, 148(4), S-1152. (doi: 10.1016/S0016-5085(15)33932-9)
McSorley, S. T. , Watt, D. G., Horgan, P. G. and McMillan, D. C. (2015) 868 Complication type and severity have an adverse effect on long-term oncological outcome following surgery for colorectal cancer. Gastroenterology, 148(4), S-1122. (doi: 10.1016/S0016-5085(15)33823-3)
Watt, D. G., McSorley, S. T. , Park, J. H. , Horgan, P. G. and McMillan, D. C. (2015) 879 The validation of C-reactive protein and albumin as predictors of post-operative infective complications and their clinical utility in patients with colorectal cancer. Gastroenterology, 148(4), S-1125. (doi: 10.1016/S0016-5085(15)33834-8)
McSorley, S.T. , Drury, M., Majumdar, P., Halsall, A. and Nalagatla, S. (2014) C-reactive protein to predict the need for surgical intervention in acute renal colic. Journal of Clinical Urology, 7(6), pp. 380-383. (doi: 10.1177/2051415813495679)
McSorley, S. , Lowndes, C., Sharma, P. and Macdonald, A. (2013) Unplanned reoperation within 30 days of surgery for colorectal cancer in NHS Lanarkshire. Colorectal Disease, 15(6), pp. 689-694. (doi: 10.1111/codi.12135) (PMID:23398663)
McSorley, S. , Kochman, A. and DeSouza, J. (2013) Grand rounds: Müllerianosis of the urinary bladder in a postmenopausal woman. Urology, 81(3), pp. 488-490. (doi: 10.1016/j.urology.2012.11.013) (PMID:23312895)
Conference or Workshop Item
Dolan, R. , McSorley, S. T. , Park, J. H. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2018) The Prognostic Value of Systemic Inflammation in Patients Undergoing Surgery for Rectal Cancer: Comparison of Composite Ratios and Cumulative Scores. Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 18-20 Jan 2018. (doi: 10.1200/JCO.2018.36.4_suppl.579)
Dolan, R. , Tilling, E., Kong, C. Y. , MacLeod, N. J., McSorley, S. T. , Park, J. H. , Glen, P., Horgan, P. G. , Laird, B. and McMillan, D. C. (2018) Evaluation of Systemic Inflammation Based Prognostic Scores in Patients with Advanced Oesophageal Cancer Receiving Palliative Radiotherapy. Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 18-20 Jan 2018.
Dolan, R. , MacLeod, N. J., McSorley, S. T. , Horgan, P. G. , Laird, B. and McMillan, D. C. (2017) Evaluation of Systemic Inflammation-based Prognostic Scores in Patients With Advanced Colorectal Cancer Receiving Palliative Pelvic Radiotherapy (RT). 2017 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 19-21 Jan 2017. (doi: 10.1200/jco.2017.35.4_suppl.558)
Dolan, R. , McSorley, S. T. , McMillan, D. C. and Horgan, P. G. (2017) Association of Ongoing Systemic Inflammatory Response (SIR) at Diagnosis With Lymph Node Retrieval and Node Positivity in Patients Undergoing Surgery for Colonic Cancer. 2017 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 19-21 Jan 2017. (doi: 10.1200/jco.2017.35.4_suppl.550)
Dolan, R. , McLeod, N., McSorley, S. , McMillan, D. and Horgan, P. (2017) Evaluation of Systemic Inflammation Based Prognostic Scoresin Patients with Advanced Rectal Cancer Receiving Palliative Pelvicradiotherapy. International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Glasgow, UK, 03-05 May 2017.
Dolan, R. , McSorley, S. , McMillan, D. and Horgan, P. (2017) Ongoing Systemic Inflammatory Response at Diagnosis is Notassociated with Lower Lymph Node Retrieval and Higher Node Positivityin Patients Undergoing Surgery for Colonic Cancer. International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Glasgow, UK, 03-05 May 2017.
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Single cell spatial transcriptomics to investigate colorectal adenoma immune contexture and its association with future polyp or cancer risk in bowel screening patients
Guts UK Charity
2024 - 2025
- Integrated Technologies for Improved Polyp Surveillance (INCISE) V2.0
Innovate UK
2023 - 2025
- Integrating digital pathology and genomic analysis to optimise and streamline colonic surveillance within the Scottish Bowel Screening Programme (SBoSP) to enable early detection of Colorectal neoplasia.
Innovate UK
2020 - 2023
Supervision
- Al Badran, Sara Samir Foad
Examining the colonic polyp microbiome and its association with future colorectal neoplasia risk in a bowel screening population