2017

Hernandez-Martinez, J.-M., Forrest, C. M., Darlington, L. G., Smith, R. A. and Stone, T. W. (2017) Quinolinic acid induces neuritogenesis in SH-SY5Y neuroblastoma cells independently of NMDA receptor activation. European Journal of Neuroscience, 45(5), pp. 700-711. (doi: 10.1111/ejn.13499) (PMID:27973747)

2015

Fatokun, A. A., Tome, M., Smith, R. A., Darlington, L. G. and Stone, T. W. (2015) Protection by the flavonoids quercetin and luteolin against peroxide or menadione-induced oxidative stress in MC3T3-E1 osteoblast cells. Natural Product Research, 29(12), pp. 1127-1132. (doi: 10.1080/14786419.2014.980252) (PMID:25427161)

2013

Khalil, O.S., Forrest, C.M., Pisar, M., Smith, R.A., Darlington, L.G. and Stone, T.W. (2013) Prenatal activation of maternal TLR3 receptors by viral-mimetic poly(I:C) modifies GluN2B expression in embryos and sonic hedgehog in offspring in the absence of kynurenine pathway activation. Immunopharmacology and Immunotoxicology, 35(5), pp. 581-593. (doi: 10.3109/08923973.2013.828745)

Roth, H., Smith, R.A. and Mackay, S. (2013) Modern day relevance of William Hunter's approach to teaching “The organ of hearing”. Clinical Anatomy, 26(5), pp. 551-555. (doi: 10.1002/ca.22220)

2012

Forrest, C.M., Khalil, O.S., Pisar, M., Smith, R.A., Darlington, L. and Stone, T.W. (2012) Prenatal activation of toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in offspring. Molecular Brain, 5(22), (doi: 10.1186/1756-6606-5-22)

2010

Roberts, R.A., Smith, R.A., Safe, S., Szabo, C., Tjalkens, R.B. and Robertson, F.M. (2010) Toxicological and pathophysiological roles of reactive oxygen and nitrogen species. Toxicology, 276(2), pp. 85-94. (doi: 10.1016/j.tox.2010.07.009)

Darlington, L.G., Forrest, C.M., Mackay, G.M., Smith, R.A., Smith, A.J., Stoy, N. and Stone, T.W. (2010) On the biological importance of the 3-hydroxyanthranilic acid: anthranilic acid ratio. International Journal of Tryptophan Research, 3, pp. 51-59.

2009

Smith, A., Tauskela, J.S., Stone, T.W. and Smith, R.A. (2009) Preconditioning with 4-aminopyridine protects cerebellar granule neurons against excitotoxicity. Brain Research, 1294, pp. 165-175. (doi: 10.1016/j.brainres.2009.07.061)

Smith, R. A. (2009) Twenty-first century challenges for in vitro neurotoxicity. Alternatives to Laboratory Animals, 37(4), pp. 367-375.

Al-Gonaiah, M., Smith, R.A. and Stone, T.W. (2009) Xanthine oxidase-induced neuronal death via the oxidation of NADH: prevention by micromolar EDTA. Brain Research, 1280, pp. 33-42. (doi: 10.1016/j.brainres.2009.05.024)

Smith, A.J., Smith, R.A. and Stone, T.W. (2009) 5-Hydroxyanthranilic acid, a tryptophan metabolite, generates oxidative stress and neuronal death via p38 activation in cultured cerebellar granule neurones. Neurotoxicity Research, 15(4), pp. 303-310. (doi: 10.1007/s12640-009-9034-0)

2008

Fatokun, A.A., Stone, T.W. and Smith, R.A. (2008) Responses of differentiated MC3T3-E1 osteoblast-like cells to reactive oxygen species. European Journal of Pharmacology, 587(1-3), pp. 35-41. (doi: 10.1016/j.ejphar.2008.03.024)

Fatokun, A.A., Stone, T.W. and Smith, R.A. (2008) Adenosine receptor ligands protect against a combination of apoptotic and necrotic cell death in cerebellar granule neurons. Experimental Brain Research, 186(1), pp. 151-160. (doi: 10.1007/s00221-007-1218-3)

Fatokun, A.A., Smith, R.A. and Stone, T.W. (2008) Resistance to kynurenic acid of the NMDA receptor-dependent toxicity of 3-nitropropionic acid and cyanide in cerebellar granule neurons. Brain Research, 1215, pp. 200-207. (doi: 10.1016/j.brainres.2008.04.013)

Fatokun, A.A., Stone, T.W. and Smith, R.A. (2008) Oxidative stress in neurodegeneration and available means of protection. Frontiers in Bioscience, 13(1), pp. 3288-3311. (doi: 10.2741/2926)

Fatokun, A.A., Stone, T.W. and Smith, R.A. (2008) Prolonged exposures of cerebellar granule neurons to S-nitroso-N-acetylpenicillamine (SNAP) induce neuronal damage independently of peroxynitrite. Brain Research, 1230(16), pp. 265-272. (doi: 10.1016/j.brainres.2008.06.109)

Hou, S.T., Jiang, S.X. and Smith, R.A. (2008) Permissive and repulsive cues and signalling pathways of axonal outgrowth and regeneration. International Review of Cell and Molecular Biology, 267(.), pp. 125-181. (doi: 10.1016/S1937-6448(08)00603-5)

Smith, A.J., Stone, T.W. and Smith, R.A. (2008) Preconditioning with NMDA protects against toxicity of 3-nitropropionic acid or glutamate in cultured cerebellar granule neurons. Neuroscience Letters, 440(3), pp. 294-298. (doi: 10.1016/j.neulet.2008.05.066)

2007

Fatokun, A., Stone, T.W. and Smith, R. (2007) Cell death in rat cerebellar granule neurons induced by hydrogen peroxide in vitro: Mechanisms and protection by adenosine receptor ligands. Brain Research, 1132, pp. 193-202. (doi: 10.1016/j.brainres.2006.11.008)

Fatokun, A., Stone, T.W. and Smith, R. (2007) Hydrogen peroxide mediates damage by xanthine and xanthine oxidase in cerebellar granule neuronal cultures. Neuroscience Letters, 416, pp. 34-38. (doi: 10.1016/j.neulet.2007.01.078)

Mackay, S. and Smith, R.A. (2007) Effects of growth factors on testicular morphogenesis. International Review of Cytology: A Survey of Cell Biology, 260, pp. 113-173. (doi: 10.1016/S0074-7696(06)60003-X)

2006

Fatokun, A., Stone, T.W. and Smith, R. (2006) Hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells: The effect of glutamate and protection by purines. Bone, 39, pp. 542-551. (doi: 10.1016/j.bone.2006.02.062)

2005

Halstead, S., Humphreys, P., Goodfellow, J., Wagner, E., Smith, R. and Willison, H. (2005) Complement inhibition abrogates nerve terminal injury in Miller Fisher syndrome. Annals of Neurology, 58, pp. 203-210. (doi: 10.1002/ana.20546)

Wallace, D. et al. (2005) Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene. Molecular Pharmacology, 67, pp. 1920-1934. (doi: 10.1124/mol.104.009423)

Wu, Z., Templeman, J., Smith, R. and Mackay, S. (2005) Effects of glial cell line-derived neurotrophic factor on isolated developing mouse Sertoli cells in vitro. Journal of Anatomy, 206, pp. 175-184.

2004

Mackay, S., Willerton, L., Ballingall, C., Henderson, N. and Smith, R. (2004) Developing mouse Sertoli cells in vitro: Effects on developing ovaries in co-culture and production of anti-Mullerian hormone. Cells Tissues Organs, 177, pp. 79-86. (doi: 10.1159/000079183)

Willerton, L., Smith, R., Russell, D. and Mackay, S. (2004) Effects of FGF9 on embryonic Sertoli cell proliferation and testicular cord formation in the mouse. International Journal of Developmental Biology, 48, pp. 637-643. (doi: 10.1387/ijdb.031778lw)

2003

Smith, R., Walker, T., Xie, X. and Hou, S. (2003) Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells. Molecular Brain Research, 116, pp. 70-79. (doi: 10.1016/S0169-328X(03)00253-5)

2002

Smith, R., Ruxton, G. and Cresswell, W. (2002) Do kleptoparasites reduce their own foraging effort in order to detect kleptoparasitic opportunities? An empirical test of a key assumption of kleptoparasitic models. Oikos, 97, pp. 205-212.

2001

Cresswell, W., Smith, R. and Ruxton, G. (2001) Absolute foraging rate and susceptibility to interference competition in blackbirds varies with patch conditions. Journal of Animal Ecology, 70, pp. 228-236.

Smith, R., Ruxton, G. and Cresswell, W. (2001) Dominance and feeding interference in small groups of blackbirds. Behavioral Ecology, 12, pp. 475-481.

Smith, R., Ruxton, G. and Cresswell, W. (2001) Patch choice decisions of wild blackbirds: the role of preharvest public information. Animal Behaviour, 61, pp. 1113-1124. (doi: 10.1006/anbe.2001.1704)

Stone, T.W. , Jones, P. and Smith, R.A. (2001) Neuroprotection by A(2A) receptor antagonists. Drug Development Research, 52, pp. 323-330.

Articles

Hernandez-Martinez, J.-M., Forrest, C. M., Darlington, L. G., Smith, R. A. and Stone, T. W. (2017) Quinolinic acid induces neuritogenesis in SH-SY5Y neuroblastoma cells independently of NMDA receptor activation. European Journal of Neuroscience, 45(5), pp. 700-711. (doi: 10.1111/ejn.13499) (PMID:27973747)

Fatokun, A. A., Tome, M., Smith, R. A., Darlington, L. G. and Stone, T. W. (2015) Protection by the flavonoids quercetin and luteolin against peroxide or menadione-induced oxidative stress in MC3T3-E1 osteoblast cells. Natural Product Research, 29(12), pp. 1127-1132. (doi: 10.1080/14786419.2014.980252) (PMID:25427161)

Khalil, O.S., Forrest, C.M., Pisar, M., Smith, R.A., Darlington, L.G. and Stone, T.W. (2013) Prenatal activation of maternal TLR3 receptors by viral-mimetic poly(I:C) modifies GluN2B expression in embryos and sonic hedgehog in offspring in the absence of kynurenine pathway activation. Immunopharmacology and Immunotoxicology, 35(5), pp. 581-593. (doi: 10.3109/08923973.2013.828745)

Roth, H., Smith, R.A. and Mackay, S. (2013) Modern day relevance of William Hunter's approach to teaching “The organ of hearing”. Clinical Anatomy, 26(5), pp. 551-555. (doi: 10.1002/ca.22220)

Forrest, C.M., Khalil, O.S., Pisar, M., Smith, R.A., Darlington, L. and Stone, T.W. (2012) Prenatal activation of toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in offspring. Molecular Brain, 5(22), (doi: 10.1186/1756-6606-5-22)

Roberts, R.A., Smith, R.A., Safe, S., Szabo, C., Tjalkens, R.B. and Robertson, F.M. (2010) Toxicological and pathophysiological roles of reactive oxygen and nitrogen species. Toxicology, 276(2), pp. 85-94. (doi: 10.1016/j.tox.2010.07.009)

Darlington, L.G., Forrest, C.M., Mackay, G.M., Smith, R.A., Smith, A.J., Stoy, N. and Stone, T.W. (2010) On the biological importance of the 3-hydroxyanthranilic acid: anthranilic acid ratio. International Journal of Tryptophan Research, 3, pp. 51-59.

Smith, A., Tauskela, J.S., Stone, T.W. and Smith, R.A. (2009) Preconditioning with 4-aminopyridine protects cerebellar granule neurons against excitotoxicity. Brain Research, 1294, pp. 165-175. (doi: 10.1016/j.brainres.2009.07.061)

Smith, R. A. (2009) Twenty-first century challenges for in vitro neurotoxicity. Alternatives to Laboratory Animals, 37(4), pp. 367-375.

Al-Gonaiah, M., Smith, R.A. and Stone, T.W. (2009) Xanthine oxidase-induced neuronal death via the oxidation of NADH: prevention by micromolar EDTA. Brain Research, 1280, pp. 33-42. (doi: 10.1016/j.brainres.2009.05.024)

Smith, A.J., Smith, R.A. and Stone, T.W. (2009) 5-Hydroxyanthranilic acid, a tryptophan metabolite, generates oxidative stress and neuronal death via p38 activation in cultured cerebellar granule neurones. Neurotoxicity Research, 15(4), pp. 303-310. (doi: 10.1007/s12640-009-9034-0)

Fatokun, A.A., Stone, T.W. and Smith, R.A. (2008) Responses of differentiated MC3T3-E1 osteoblast-like cells to reactive oxygen species. European Journal of Pharmacology, 587(1-3), pp. 35-41. (doi: 10.1016/j.ejphar.2008.03.024)

Fatokun, A.A., Stone, T.W. and Smith, R.A. (2008) Adenosine receptor ligands protect against a combination of apoptotic and necrotic cell death in cerebellar granule neurons. Experimental Brain Research, 186(1), pp. 151-160. (doi: 10.1007/s00221-007-1218-3)

Fatokun, A.A., Smith, R.A. and Stone, T.W. (2008) Resistance to kynurenic acid of the NMDA receptor-dependent toxicity of 3-nitropropionic acid and cyanide in cerebellar granule neurons. Brain Research, 1215, pp. 200-207. (doi: 10.1016/j.brainres.2008.04.013)

Fatokun, A.A., Stone, T.W. and Smith, R.A. (2008) Oxidative stress in neurodegeneration and available means of protection. Frontiers in Bioscience, 13(1), pp. 3288-3311. (doi: 10.2741/2926)

Fatokun, A.A., Stone, T.W. and Smith, R.A. (2008) Prolonged exposures of cerebellar granule neurons to S-nitroso-N-acetylpenicillamine (SNAP) induce neuronal damage independently of peroxynitrite. Brain Research, 1230(16), pp. 265-272. (doi: 10.1016/j.brainres.2008.06.109)

Hou, S.T., Jiang, S.X. and Smith, R.A. (2008) Permissive and repulsive cues and signalling pathways of axonal outgrowth and regeneration. International Review of Cell and Molecular Biology, 267(.), pp. 125-181. (doi: 10.1016/S1937-6448(08)00603-5)

Smith, A.J., Stone, T.W. and Smith, R.A. (2008) Preconditioning with NMDA protects against toxicity of 3-nitropropionic acid or glutamate in cultured cerebellar granule neurons. Neuroscience Letters, 440(3), pp. 294-298. (doi: 10.1016/j.neulet.2008.05.066)

Fatokun, A., Stone, T.W. and Smith, R. (2007) Cell death in rat cerebellar granule neurons induced by hydrogen peroxide in vitro: Mechanisms and protection by adenosine receptor ligands. Brain Research, 1132, pp. 193-202. (doi: 10.1016/j.brainres.2006.11.008)

Fatokun, A., Stone, T.W. and Smith, R. (2007) Hydrogen peroxide mediates damage by xanthine and xanthine oxidase in cerebellar granule neuronal cultures. Neuroscience Letters, 416, pp. 34-38. (doi: 10.1016/j.neulet.2007.01.078)

Mackay, S. and Smith, R.A. (2007) Effects of growth factors on testicular morphogenesis. International Review of Cytology: A Survey of Cell Biology, 260, pp. 113-173. (doi: 10.1016/S0074-7696(06)60003-X)

Fatokun, A., Stone, T.W. and Smith, R. (2006) Hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells: The effect of glutamate and protection by purines. Bone, 39, pp. 542-551. (doi: 10.1016/j.bone.2006.02.062)

Halstead, S., Humphreys, P., Goodfellow, J., Wagner, E., Smith, R. and Willison, H. (2005) Complement inhibition abrogates nerve terminal injury in Miller Fisher syndrome. Annals of Neurology, 58, pp. 203-210. (doi: 10.1002/ana.20546)

Wallace, D. et al. (2005) Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene. Molecular Pharmacology, 67, pp. 1920-1934. (doi: 10.1124/mol.104.009423)

Wu, Z., Templeman, J., Smith, R. and Mackay, S. (2005) Effects of glial cell line-derived neurotrophic factor on isolated developing mouse Sertoli cells in vitro. Journal of Anatomy, 206, pp. 175-184.

Mackay, S., Willerton, L., Ballingall, C., Henderson, N. and Smith, R. (2004) Developing mouse Sertoli cells in vitro: Effects on developing ovaries in co-culture and production of anti-Mullerian hormone. Cells Tissues Organs, 177, pp. 79-86. (doi: 10.1159/000079183)

Willerton, L., Smith, R., Russell, D. and Mackay, S. (2004) Effects of FGF9 on embryonic Sertoli cell proliferation and testicular cord formation in the mouse. International Journal of Developmental Biology, 48, pp. 637-643. (doi: 10.1387/ijdb.031778lw)

Smith, R., Walker, T., Xie, X. and Hou, S. (2003) Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells. Molecular Brain Research, 116, pp. 70-79. (doi: 10.1016/S0169-328X(03)00253-5)

Smith, R., Ruxton, G. and Cresswell, W. (2002) Do kleptoparasites reduce their own foraging effort in order to detect kleptoparasitic opportunities? An empirical test of a key assumption of kleptoparasitic models. Oikos, 97, pp. 205-212.

Cresswell, W., Smith, R. and Ruxton, G. (2001) Absolute foraging rate and susceptibility to interference competition in blackbirds varies with patch conditions. Journal of Animal Ecology, 70, pp. 228-236.

Smith, R., Ruxton, G. and Cresswell, W. (2001) Dominance and feeding interference in small groups of blackbirds. Behavioral Ecology, 12, pp. 475-481.

Smith, R., Ruxton, G. and Cresswell, W. (2001) Patch choice decisions of wild blackbirds: the role of preharvest public information. Animal Behaviour, 61, pp. 1113-1124. (doi: 10.1006/anbe.2001.1704)

Stone, T.W. , Jones, P. and Smith, R.A. (2001) Neuroprotection by A(2A) receptor antagonists. Drug Development Research, 52, pp. 323-330.