2024

Galbraith, N. J. et al. (2024) TAK1 expression is associated with increased PD-L1 and decreased cancer-specific survival in microsatellite-stable colorectal cancer. Translational Oncology, 48, 102064. (doi: 10.1016/j.tranon.2024.102064) (PMID:39068768)

Golder, A. M. , Ferguson, M., McMillan, P., Mansouri, D. , Horgan, P. G. , Roxburgh, C. S. , Dolan, R. D. , McGovern, J. and McMillan, D. (2024) CT-derived body composition and differential association with age, TNM stage and systemic inflammation in patients with colon cancer. Scientific Reports, 14, 15673. (doi: 10.1038/s41598-024-65871-y) (PMID:38977870) (PMCID:PMC11231341)

Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4)

McGovern, J., Mackay, C., Freireich, R., Golder, A. M. , Dolan, R. D. , Horgan, P. G. , Holroyd, D., Jamieson, N. B. and McMillan, D. C. (2024) The relationship between liver volume, clinicopathological characteristics and survival in patients undergoing resection with curative intent for non-metastatic colonic cancer. Tomography, 10(3), pp. 349-359. (doi: 10.3390/tomography10030027) (PMID:38535769) (PMCID:PMC10974240)

Johnstone, M. S., McSorley, S. T. , McMillan, D. C. , Horgan, P. G. and Mansouri, D. (2024) The relationship between systemic inflammatory response, screen detection and outcome in colorectal cancer. Colorectal Disease, 26(1), pp. 81-94. (doi: 10.1111/codi.16824) (PMID:38095280)

2023

Galbraith, N. J. et al. (2023) Effect of differing flap reconstruction strategies in perineal closure following advanced pelvic oncological resection: a retrospective cohort study. International Journal of Surgery, 109(11), pp. 3375-3382. (doi: 10.1097/JS9.0000000000000617) (PMID:37678294) (PMCID:PMC10651229)

McMahon, R. K., O'Cathail, S. M. , Nair, H., Steele, C. W. , Platt, J. J., Digby, M., McDonald, A. C., Horgan, P. G. and Roxburgh, C. S.D. (2023) The neoadjuvant rectal score and a novel magnetic resonance imaging based neoadjuvant rectal score are stage independent predictors of long-term outcome in locally advanced rectal cancer. Colorectal Disease, 25(9), pp. 1783-1794. (doi: 10.1111/codi.16667) (PMID:37485654)

McGovern, J., Leadbitter, S., Miller, G., Hounat, A., Kamande, I., Dolan, R. D. , Horgan, P. G. , Chang, D. K. , Jamieson, N. B. and McMillan, D. C. (2023) The relationship between heart rate variability and TNM stage, co-morbidity, systemic inflammation and survival in patients with primary operable colorectal cancer. Scientific Reports, 13, 8157. (doi: 10.1038/s41598-023-35396-x) (PMID:37208421) (PMCID:PMC10198985)

Wood, C. S. et al. (2023) Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases. Cancer Research, 83(8), pp. 1329-1344. (doi: 10.1158/0008-5472.CAN-22-2794) (PMID:37057593) (PMCID:PMC10102851)

Alexander, P.G., van Wyk, H.C. , Pennel, K.A.F., Hay, J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S.D. , Edwards, J. and Park, J.H. (2023) The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer. British Journal of Cancer, 128(4), pp. 556-567. (doi: 10.1038/s41416-022-02069-x) (PMID:36476660) (PMCID:PMC9938140)

McGovern, J., Grayston, A., Coates, D., Leadbitter, S., Hounat, A., Horgan, P. G. , Dolan, R. D. and McMillan, D. C. (2023) The relationship between the modified frailty index score (mFI-5), malnutrition, body composition, systemic inflammation and short-term clinical outcomes in patients undergoing surgery for colorectal cancer. BMC Geriatrics, 23, 9. (doi: 10.1186/s12877-022-03703-2) (PMID:36609242) (PMCID:PMC9817261)

McGovern, J. et al. (2023) The relationship between computed tomography-derived sarcopenia, cardiopulmonary exercise testing performance, systemic inflammation, and survival in good performance status patients with oesophago-gastric cancer undergoing neoadjuvant treatment. JCSM Clinical Reports, 8(1), pp. 3-11. (doi: 10.1002/crt2.57)

2022

Golder, A. M. , Sin, L. K. E., Alani, F., Dolan, R. , Mansouri, D. , Horgan, P. G. , McMillan, D. C. and Roxburgh, C. S. (2022) The relationship between the mode of presentation, CT-derived body composition, systemic inflammatory grade and survival in colon cancer. Journal of Cachexia, Sarcopenia and Muscle, 13(6), pp. 2863-2874. (doi: 10.1002/jcsm.13097) (PMID:36218135) (PMCID:PMC9745485)

Pennel, K. A. F. et al. (2022) CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer. Journal of Pathology: Clinical Research, 8(6), pp. 509-520. (doi: 10.1002/cjp2.290) (PMID:35879507) (PMCID:PMC9535100)

Golder, A.M. , Mshihadani, A., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and Mansouri, D. (2022) Route to diagnosis of colorectal cancer and association with survival within the context of a bowel screening programme. Public Health, 211, pp. 53-61. (doi: 10.1016/j.puhe.2022.06.032) (PMID:36027788)

McGovern, J., Dolan, R. D. , Maguire, D., Horgan, P. , Laird, B. J. and McMillan, D. C. (2022) A comparison of CT-body composition measurements in non-cancer and cancer patients from a single UK centre. Journal of Frailty, Sarcopenia and Falls, 7(3), pp. 117-122. (doi: 10.22540/JFSF-07-117) (PMID:36119551) (PMCID:PMC9433946)

Alexander, P. G. et al. (2022) The relationship between the Glasgow Microenvironment Score and markers of epithelial-mesenchymal transition in TNM II-III colorectal cancer. Human Pathology, 127, pp. 1-11. (doi: 10.1016/j.humpath.2022.05.012) (PMID:35623467)

Cheong, C. M., Golder, A. , Horgan, P. , Roxburgh, C. and McMillan, D. (2022) Relationship between pre‑operative glycated haemoglobin and surgical site infection in patients undergoing elective colon cancer surgery. Oncology Letters, 24(3), 296. (doi: 10.3892/ol.2022.13416) (PMID:35949622) (PMCID:PMC9353220)

Di Rollo, D. G., McGovern, J., Morton, C., Miller, G., Dolan, R. , Horgan, P. G. , McMillan, D. C. and Mansouri, D. (2022) Relationship between BMI, CT-derived body composition and colorectal neoplasia in a bowel screening population. Scottish Medical Journal, 67(3), pp. 93-102. (doi: 10.1177/00369330221102237) (PMID:35603880)

McGovern, J., Golder, A. M. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2022) The combination of computed tomography-derived muscle mass and muscle density and relationship with clinicopathological characteristics and survival in patients undergoing potentially curative surgery for colorectal cancer. JCSM Clinical Reports, 7(3), pp. 65-76. (doi: 10.1002/crt2.54)

Patel, M. et al. (2022) Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer. British Journal of Cancer, 126(12), pp. 1704-1714. (doi: 10.1038/s41416-022-01729-2) (PMID:35173303) (PMCID:PMC9174220)

Ross, F. A., Park, J. H. , Mansouri, D. , Combet, E. , Horgan, P. G. , McMillan, D. C. and Roxburgh, C. S.D. (2022) The role of faecal calprotectin in diagnosis and staging of colorectal neoplasia: a systematic review and meta-analysis. BMC Gastroenterology, 22, 176. (doi: 10.1186/s12876-022-02220-1) (PMID:35397505) (PMCID:PMC8994317)

McGovern, J., Dolan, R. D. , Horgan, P. G. , Laird, B. J. and McMillan, D. C. (2022) The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review. BMC Geriatrics, 22, 260. (doi: 10.1186/s12877-022-02928-5) (PMID:35351011) (PMCID:PMC8962494)

Golder, A. M. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S.D. (2022) Determinants of emergency presentation in patients with colorectal cancer: a systematic review and meta-analysis. Scientific Reports, 12, 4366. (doi: 10.1038/s41598-022-08447-y) (PMID:35288664) (PMCID:PMC8921241)

Ross, F. A., Park, J. H. , Mansouri, D. , Little, C., Di Rollo, D. G., Combet, E. , Van Wyk, H. , Horgan, P. G. , McMillan, D. C. and Roxburgh, C. S. D. (2022) The role of faecal calprotectin in the identification of colorectal neoplasia in patients attending for screening colonoscopy. Colorectal Disease, 24(2), pp. 188-196. (doi: 10.1111/codi.15942) (PMID:34614299)

Cheong, C. M., Golder, A. M. , Horgan, P. D. , McMillan, D. C. and Roxburgh, C. S.D. (2022) Evaluation of clinical prognostic variables on short-term outcome for colorectal cancer surgery: an overview and minimum dataset. Cancer Treatment and Research Communications, 31, 100544. (doi: 10.1016/j.ctarc.2022.100544) (PMID:35248885)

2021

McGovern, J., Dolan, R. D. , Horgan, P. G. , Laird, B. J. and McMillan, D. C. (2021) Computed tomography-defined low skeletal muscle index and density in cancer patients: observations from a systematic review. Journal of Cachexia, Sarcopenia and Muscle, 12(6), pp. 1408-1417. (doi: 10.1002/jcsm.12831) (PMID:34664431) (PMCID:PMC8718024)

Knight, K. A., Drami, I., McMillan, D. C. , Horgan, P. G. , Park, J. H. , Jenkins, J. T. and Roxburgh, C. S.D. (2021) Vascular calcification and response to neoadjuvant therapy in locally advanced rectal cancer: an exploratory study. Journal of Cancer Research and Clinical Oncology, 147(11), pp. 3409-3420. (doi: 10.1007/s00432-021-03570-1) (PMID:33710416) (PMCID:PMC8484095)

Lampis, A. et al. (2021) MIR21-induced loss of junctional adhesion molecule A promotes activation of oncogenic pathways, progression and metastasis in colorectal cancer. Cell Death and Differentiation, 28, pp. 2970-2982. (doi: 10.1038/s41418-021-00820-0) (PMID:34226680) (PMCID:PMC8481293)

Johnstone, M. S., McMillan, D. C. , Horgan, P. G. and Mansouri, D. (2021) The relationship between co-morbidity, screen-detection and outcome in patients undergoing resection for colorectal cancer. World Journal of Surgery, 45(7), pp. 2251-2260. (doi: 10.1007/s00268-021-06079-3) (PMID:33774690) (PMCID:PMC8154830)

Mansouri, D. , McSorley, S. T. , Park, J. H. , Orange, C., Horgan, P. G. , McMillan, D. C. and Edwards, J. (2021) The inflammatory microenvironment in screen-detected premaligant adenomatous polyps: early results from the integrated technologies for improved polyp surveillance (INCISE) project. European Journal of Gastroenterology and Hepatology, 33(7), pp. 983-989. (doi: 10.1097/MEG.0000000000002202) (PMID:34034277)

Knight, K. A., Hon Fei, C., Boland, K. F., Dolan, D. R., Golder, A. M. , McMillan, D. C. , Horgan, P. G. , Black, D. H., Park, J. H. and Roxburgh, C. S.D. (2021) Aortic calcification is associated with non-infective rather than infective postoperative complications following colorectal cancer resection: an observational cohort study. European Radiology, 31(6), pp. 4319-4329. (doi: 10.1007/s00330-020-07189-7) (PMID:33201280)

Al-Badran, S. S.F. et al. (2021) Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 7(2), pp. 121-134. (doi: 10.1002/cjp2.193) (PMID:33338327)

Alexander, P.G. et al. (2021) The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. British Journal of Cancer, 124, pp. 786-796. (doi: 10.1038/s41416-020-01168-x) (PMID:33223535)

Alhayyan, A. M. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2021) The effect of anesthesia on the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colorectal cancer in the context of an enhanced recovery pathway: A prospective cohort study. Medicine, 100(2), e23997. (doi: 10.1097/MD.0000000000023997) (PMID:33466141) (PMCID:PMC7808526)

Knight, K., Choong, J.X., McKee, R.F., Anderson, J.H., Horgan, P.G. , McMillan, D.C. , McDonald, A. and Roxburgh, C.S. (2021) The influence of systemic inflammation on treatment response and survival in anal squamous cell cancer. Clinical Oncology, 33(1), e22-e30. (doi: 10.1016/j.clon.2020.06.010) (PMID:32709540)

2020

Dolan, R. D. , Maclay, J. D., Abbass, T., Colville, D., Buali, F., MacLeod, N., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2020) The relationship between 18F-FDG-PETCT-derived tumour metabolic activity, nutritional risk, body composition, systemic inflammation and survival in patients with lung cancer. Scientific Reports, 10, 20819. (doi: 10.1038/s41598-020-77269-7) (PMID:33257741) (PMCID:PMC7705735)

Dolan, R. D. , Alwahid, M., McSorley, S. T. , Park, J. H. , Stevenson, R. P., Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2020) A comparison of the prognostic value of composite ratios and cumulative scores in patients with operable rectal cancer. Scientific Reports, 10, 17965. (doi: 10.1038/s41598-020-73909-0) (PMID:33087753) (PMCID:PMC7578034)

Abbass, T. , Dolan, R. D. , Horgan, P. G. and McMillan, D. C. (2020) The relationship between systemic inflammation, body composition and clinical outcomes in patients with operable colorectal cancer at low and medium to high nutritional risk. JCSM Clinical Reports, 5(4), pp. 99-107. (doi: 10.1002/crt2.25)

Roseweir, A. K. et al. (2020) Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. Journal of Pathology: Clinical Research, 6(4), pp. 283-296. (doi: 10.1002/cjp2.171) (PMID:32401426) (PMCID:PMC7578335)

Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2020) Authors' reply: Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short-term outcomes following left-sided colonic and rectal resections. BJS Open, 4(4), pp. 730-731. (doi: 10.1002/bjs5.50286) (PMID:32297454) (PMCID:PMC7397349)

Park, J. H. , Fuglestad, A. J., Køstner, A. H., Oliwa, A., Graham, J., Horgan, P. G. , Roxburgh, C. S.D. , Kersten, C. and McMillan, D. C. (2020) Systemic inflammation and outcome in 2295 patients with stage I-III colorectal cancer from Scotland and Norway: First results from the ScotScan Colorectal Cancer Group. Annals of Surgical Oncology, 27, pp. 2784-2794. (doi: 10.1245/s10434-020-08268-1) (PMID:32248375) (PMCID:PMC7334267)

Dolan, R. D. , Tien, Y.-T., Horgan, P. G. , Edwards, C. A. and McMillan, D. C. (2020) The relationship between computed tomography‐derived body composition and survival in colorectal cancer: the effect of image software. Journal of Cachexia, Sarcopenia and Muscle: Rapid Communications, 3(2), pp. 81-90. (doi: 10.1002/rco2.15)

McSorley, S. T. , Anderson, J. H., Whittle, T., Roxburgh, C. S. , Horgan, P. G. , McMillan, D. C. and Steele, C. W. (2020) The impact of preoperative systemic inflammation on the efficacy of intravenous iron infusion to correct anaemia prior to surgery for colorectal cancer. Perioperative Medicine, 9, 17. (doi: 10.1186/s13741-020-00146-4) (PMID:32537137) (PMCID:PMC7288411)

ALHAYYAN, A. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2020) The relationship between anaesthetic technique, clinicopathological characteristics and the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colon cancer. PLoS ONE, 15(4), e0228580. (doi: 10.1371/journal.pone.0228580) (PMID:32348308) (PMCID:PMC7190171)

Alhayyan, A. , McSorley, S. , Roxburgh, C. , Kearns, R. , Horgan, P. and McMillan, D. (2020) The effect of anesthesia on the postoperative systemic inflammatory response in patients undergoing surgery: a systematic review and meta-analysis. Surgery Open Science, 2(1), pp. 1-21. (doi: 10.1016/j.sopen.2019.06.001) (PMID:32754703) (PMCID:PMC7391900)

Knight, K.A., Horgan, P.G. , McMillan, D.C. , Roxburgh, C.S.D. and Park, J.H. (2020) The relationship between aortic calcification and anastomotic leak following gastrointestinal resection: a systematic review. International Journal of Surgery, 73, pp. 42-49. (doi: 10.1016/j.ijsu.2019.11.023) (PMID:31765846)

McSorley, S. T. , Tham, A., Dolan, R. D. , Steele, C. W. , Ramsingh, J., Roxburgh, C. , Horgan, P. G. and McMillan, D. C. (2020) Perioperative blood transfusion is associated with the postoperative systemic inflammatory response and poorer outcomes following surgery for colorectal cancer. Annals of Surgical Oncology, 27, pp. 833-843. (doi: 10.1245/s10434-019-07984-7) (PMID:31664621) (PMCID:PMC7000540)

2019

Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2019) Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short‐term outcomes following left‐sided colonic and rectal resections. BJS Open, 3(6), pp. 830-839. (doi: 10.1002/bjs5.50224) (PMID:31832590) (PMCID:PMC6887908)

Golder, A. M. , McSorley, S. T. , Kearns, R. J. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S. (2019) Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: a qualitative study. Annals of Medicine and Surgery, 48, pp. 23-28. (doi: 10.1016/j.amsu.2019.10.007) (PMID:31687135) (PMCID:PMC6820077)

Almasaudi, A. S., Dolan, R. D. , McSorley, S. T. , Horgan, P. G. , Edwards, C. and McMillan, D. C. (2019) Relationship between computed tomography-derived body composition, sex, and post-operative complications in patients with colorectal cancer. European Journal of Clinical Nutrition, 73(11), pp. 1450-1457. (doi: 10.1038/s41430-019-0414-0) (PMID:30858540)

Jackstadt, R. et al. (2019) Epithelial NOTCH signaling rewires the tumor microenvironment of colorectal cancer to drive poor-prognosis subtypes and metastasis. Cancer Cell, 36(3), 319-336.e7. (doi: 10.1016/j.ccell.2019.08.003) (PMID:31526760) (PMCID:PMC6853173)

Park, J. H. , van Wyk, H. , McMillan, D. C. , Edwards, J. , Orange, C., Horgan, P. G. and Roxburgh, C. S.D. (2019) Pre-operative, biopsy-based assessment of the tumour microenvironment in patients with primary operable colorectal cancer. Journal of Pathology: Clinical Research, 6(1), pp. 30-39. (doi: 10.1002/cjp2.143) (PMID:31486287) (PMCID:PMC6966701)

Dolan, R. , Laird, B. J.A., Klepstad, P., Kaasa, S., Horgan, P. G. , Paulsen, Ø. and McMillan, D. C. (2019) An exploratory study examining the relationship between performance status and systemic inflammation frameworks and cytokine profiles in patients with advanced cancer. Medicine, 98(37), e17019. (doi: 10.1097/MD.0000000000017019) (PMID:31517821) (PMCID:PMC6750290)

McSorley, S. T. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. , MacKay, G. J. and McMillan, D. C. (2019) Possible dose dependent effect of perioperative dexamethasone and laparoscopic surgery on the postoperative systemic inflammatory response and complications following surgery for colon cancer. European Journal of Surgical Oncology, 45(9), pp. 1613-1618. (doi: 10.1016/j.ejso.2019.05.020) (PMID:31130339)

McSorley, S. T. , Tham, A., Steele, C. W. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2019) Quantitative data on red cell measures of iron status and their relation to the magnitude of the systemic inflammatory response and survival in patients with colorectal cancer. European Journal of Surgical Oncology, 45(7), pp. 1205-1211. (doi: 10.1016/j.ejso.2019.02.027) (PMID:30850153)

Roseweir, A. K. , Clark, J., McSorley, S. T. , vanWyk, H. C. , Quinn, J. A. , Horgan, P. G. , McMillan, D. C. , Park, J. H. and Edwards, J. (2019) The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer. International Journal of Cancer, 144(9), pp. 2320-2329. (doi: 10.1002/ijc.32045) (PMID:30521130)

Dolan, R. D. , McLees, N. G., Irfan, A., McSorley, S. T. , Horgan, P. G. , Colville, D. and McMillan, D. C. (2019) The relationship between tumour glucose metabolism and host systemic inflammatory responses in patients with cancer: a systematic review. Journal of Nuclear Medicine, 60(4), pp. 467-471. (doi: 10.2967/jnumed.118.216697) (PMID:30166353)

Almasaudi, A. S., McSorley, S. T. , Horgan, P. G. , McMillan, D. C. and Edwards, C. A. (2019) The relationship between body mass index, sex, and postoperative outcomes in patients undergoing potentially curative surgery for colorectal cancer. Clinical Nutrition ESPEN, 30, pp. 185-189. (doi: 10.1016/j.clnesp.2018.12.084) (PMID:30904219)

Roseweir, A. K. , Powell, A. G.M.T., Horstman, S. L., Inthagard, J., Park, J. A. , McMillan, D. C. , Horgan, P. G. and Edwards, J. (2019) Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer. Cellular Signalling, 56, pp. 15-22. (doi: 10.1016/j.cellsig.2019.01.007) (PMID:30684564)

McSorley, S. , Johnstone, M., Steele, C. W. , Roxburgh, C. S.D. , Horgan, P. G. , McMillan, D. C. and Mansouri, D. (2019) Normocytic anaemia is associated with systemic inflammation and poorer survival in patients with colorectal cancer treated with curative intent. International Journal of Colorectal Disease, 34(3), pp. 401-408. (doi: 10.1007/s00384-018-3211-7) (PMID:30515556)

Dolan, R. , Almasaudi, A. S., Dieu, L. B., Horgan, P. G. , McSorley, S. T. and McMillan, D. C. (2019) The relationship between computed tomography‐derived body composition, systemic inflammatory response, and survival in patients undergoing surgery for colorectal cancer. Journal of Cachexia, Sarcopenia and Muscle, 10(1), pp. 111-122. (doi: 10.1002/jcsm.12357) (PMID:30460764) (PMCID:PMC6438413)

Roseweir, A.K. et al. (2019) A novel tumor-based epithelial-to-mesenchymal transition score that associates with prognosis and metastasis in patients with stage II/III colorectal cancer. International Journal of Cancer, 144(1), pp. 150-159. (doi: 10.1002/ijc.31739) (PMID:29992570)

Van Wyk, H. , Roseweir, A. , Alexander, P. , Park, J. H. , Horgan, P. , McMillan, D. and Edwards, J. (2019) The relationship between tumour budding, tumour microenvironment and survival in patients with primary operable colorectal cancer. Annals of Surgical Oncology, 26, pp. 4397-4404. (doi: 10.1245/s10434-019-07931-6) (PMID:31605345) (PMCID:PMC6863941)

2018

Dolan, R. D. , Laird, B., Horgan, P. G. and McMillan, D. C. (2018) The prognostic value of the systemic inflammatory response in randomised clinical trials in cancer: A systematic review. Critical Reviews in Oncology/Hematology, 132, pp. 130-137. (doi: 10.1016/j.critrevonc.2018.09.016)

Park, J. H. et al. (2018) Staging the tumor and staging the host: A two centre, two country comparison of systemic inflammatory responses of patients undergoing resection of primary operable colorectal cancer. American Journal of Surgery, 216(3), pp. 458-464. (doi: 10.1016/j.amjsurg.2017.08.044) (PMID:28967380)

EuroSurg Collaborative, (2018) Body mass index and complications following major gastrointestinal surgery: a prospective, international cohort study and meta-analysis. Colorectal Disease, 20(8), O215-O225. (doi: 10.1111/codi.14292) (PMID:29897171)

McSorley, S. T. , Black, D. H., Horgan, P. G. and McMillan, D. C. (2018) The relationship between tumour stage, systemic inflammation, body composition and survival in patients with colorectal cancer. Clinical Nutrition, 37(4), pp. 1279-1285. (doi: 10.1016/j.clnu.2017.05.017) (PMID:28566220)

Roseweir, A. K. , Halcrow, E. S., Chichilo, S., Powell, A. G.M.T., McMillan, D. C. , Horgan, P. G. and Edwards, J. (2018) ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer. British Journal of Cancer, 119, pp. 323-329. (doi: 10.1038/s41416-018-0174-y) (PMID:29988110) (PMCID:PMC6070918)

Dolan, R. D. , McSorley, S. T. , Park, J. H. , Watt, D. G. , Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2018) The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores. British Journal of Cancer, 119(1), pp. 40-51. (doi: 10.1038/s41416-018-0095-9) (PMID:29789606)

Park, J.H. , Horgan, P.G. and McMillan, D.C. (2018) In reply to: “Meyer CP, et al. The association of hypoalbuminemia with early perioperative outcomes – A comprehensive assessment across 16 major procedures”. American Journal of Surgery, 216(1), pp. 174-175. (doi: 10.1016/j.amjsurg.2016.12.023) (PMID:28082008)

Patel, M., Horgan, P. G. , McMillan, D. C. and Edwards, J. (2018) NF-κB pathways in the development and progression of colorectal cancer. Translational Research, 197, pp. 43-56. (doi: 10.1016/j.trsl.2018.02.002) (PMID:29550444)

McSorley, S. T. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2018) The relationship between cardiopulmonary exercise test variables, the systemic inflammatory response, and complications following surgery for colorectal cancer. Perioperative Medicine, 7(1), 11. (doi: 10.1186/s13741-018-0093-8) (PMID:29983927) (PMCID:PMC6003031)

Roseweir, A. K. et al. (2018) Predictive biomarkers for endocrine therapy: retrospective study in Tamoxifen and Exemestane Adjuvant Multinational (TEAM) trial. Journal of the National Cancer Institute, 110(6), pp. 616-627. (doi: 10.1093/jnci/djx255) (PMID:29917140)

McSorley, S. T. , Khor, B. Y., Tsang, K., Colville, D., Han, S., Horgan, P. G. and McMillan, D. C. (2018) The relationship between 18F FDG-PETCT derived markers of tumour metabolism and systemic inflammation in patients with recurrent disease following surgery for colorectal cancer. Colorectal Disease, 20(5), pp. 407-415. (doi: 10.1111/codi.13973)

Maliampurakal, A. J., McMillan, D. C. , Anderson, J. H., Horgan, P. G. and Mansouri, D. (2018) Factors associated with the efficacy of polyp detection during routine flexible sigmoidoscopy. Frontline Gastroenterology, 9(2), pp. 135-142. (doi: 10.1136/flgastro-2017-100849) (PMID:29588842)

Dolan, R. , McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2018) Determinants of lymph node count and positivity in patients undergoing surgery for colon cancer. Medicine, 97(13), e0185. (doi: 10.1097/MD.0000000000010185) (PMID:29595652) (PMCID:29595652)

McSorley, S. T. , Mansouri, D. , Horgan, P. G. and McMillan, D. C. (2018) Comment on "the important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial". Annals of Surgery, 267(3), e49. (doi: 10.1097/SLA.0000000000002053) (PMID:27759622)

Patel, M., McSorley, S. T. , Park, J. H. , Roxburgh, C. S.D. , Edwards, J. , Horgan, P. G. and McMillan, D. C. (2018) The relationship between right-sided tumour location, tumour microenvironment, systemic inflammation, adjuvant therapy and survival in patients undergoing surgery for colon and rectal cancer. British Journal of Cancer, 118(5), pp. 705-712. (doi: 10.1038/bjc.2017.441) (PMID:29337962) (PMCID:PMC5846060)

Dolan, R. , McSorley, S. T. , Park, J. H. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2018) The Prognostic Value of Systemic Inflammation in Patients Undergoing Surgery for Rectal Cancer: Comparison of Composite Ratios and Cumulative Scores. Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 18-20 Jan 2018. (doi: 10.1200/JCO.2018.36.4_suppl.579)

Dolan, R. , Tilling, E., Kong, C. Y. , MacLeod, N. J., McSorley, S. T. , Park, J. H. , Glen, P., Horgan, P. G. , Laird, B. and McMillan, D. C. (2018) Evaluation of Systemic Inflammation Based Prognostic Scores in Patients with Advanced Oesophageal Cancer Receiving Palliative Radiotherapy. Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 18-20 Jan 2018.

2017

Dolan, R. D. , Lim, J., Mcsorley, S. T. , Horgan, P. G. and McMillan, D. C. (2017) The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis. Scientific Reports, 7, 16717. (doi: 10.1038/s41598-017-16955-5) (PMID:29196718) (PMCID:PMC5711862)

Dolan, R. D. , McSorley, S. T. , McMillan, D. C. and Horgan, P. G. (2017) Attitudes of surgeons to the use of postoperative markers of the systemic inflammatory response following elective surgery. Annals of Medicine and Surgery, 21, pp. 14-19. (doi: 10.1016/j.amsu.2017.07.046) (PMID:28761641) (PMCID:PMC5524306)

Watt, D. G. , Ramanathan, M. L., McSorley, S. T. , Walley, K., Park, J. H. , Horgan, P. G. and McMillan, D. C. (2017) Clinicopathological determinants of an elevated systemic inflammatory response following elective potentially curative resection for colorectal cancer. Annals of Surgical Oncology, 24(9), pp. 2588-2594. (doi: 10.1245/s10434-017-5987-z) (PMID:28695389) (PMCID:PMC5539269)

Dolan, R. D. , McSorley, S. T. , Horgan, P. G. , Laird, B. and McMillan, D. C. (2017) The role of the systemic inflammatory response in predicting outcomes in patients with advanced inoperable cancer: Systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 116, pp. 134-146. (doi: 10.1016/j.critrevonc.2017.06.002) (PMID:28693795)

Mcsorley, S. T. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2017) The impact of preoperative dexamethasone on the magnitude of the postoperative systemic inflammatory response and complications following surgery for colorectal cancer. Annals of Surgical Oncology, 24(8), pp. 2104-2112. (doi: 10.1245/s10434-017-5817-3) (PMID:28251379)

Park, J. H. , Roxburgh, C. S.D. , Edwards, J. , Horgan, P. G. and McMillan, D. C. (2017) In reply to "Hynes S.O. et al. Back to the future: routine morphological assessment of the tumour microenvironment is prognostic in stage II/III colon cancer in a large population-based study". Histopathology, 71(2), pp. 326-327. (doi: 10.1111/his.13195) (PMID:28226191)

Roseweir, A. K. , McMillan, D. C. , Horgan, P. G. and Edwards, J. (2017) Colorectal cancer subtypes: Translation to routine clinical pathology. Cancer Treatment Reviews, 57, pp. 1-7. (doi: 10.1016/j.ctrv.2017.04.006) (PMID:28505475)

Park, J.H. , Van Wyk, H. , Roxburgh, C.S.D. , Horgan, P.G. , Edwards, J. and McMillan, D.C. (2017) Tumour invasiveness, the local and systemic environment and the basis of staging systems in colorectal cancer. British Journal of Cancer, 116, pp. 1444-1450. (doi: 10.1038/bjc.2017.108)

Bennett, L., Mallon, E. A., Horgan, P. G. , Paul, A., McMillan, D. C. and Edwards, J. (2017) The relationship between members of the canonical NF-KB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer. Oncotarget, 8(20), pp. 33002-33013. (doi: 10.18632/oncotarget.16031) (PMID:28423692)

Dreyer, S. B., Powell, A. G.M.T., McSorley, S. T. , Waterston, A., Going, J. J., Edwards, J. , McMillan, D. C. and Horgan, P. G. (2017) The pretreatment systemic inflammatory response is an important determinant of poor pathologic response for patients undergoing neoadjuvant therapy for rectal cancer. Annals of Surgical Oncology, 24(5), pp. 1295-1303. (doi: 10.1245/s10434-016-5684-3) (PMID:27873100)

McSorley, S. T. , Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2017) Re: Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial). British Medical Journal, 357, j1455.

Bennett, L., Quinn, J. , McCall, P., Mallon, E. A., Horgan, P. G. , McMillan, D. C. , Paul, A. and Edwards, J. (2017) High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer. International Journal of Cancer, 140(7), pp. 1633-1644. (doi: 10.1002/ijc.30578) (PMID:28006839)

Park, J. H. , Van Wyk, H. C., McMillan, D. C. , Quinn, J. A. , Clark, J., Roxburgh, C. , Horgan, P. G. and Edwards, J. (2017) Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host. Clinical Cancer Research, 23(7), pp. 1698-1709. (doi: 10.1158/1078-0432.CCR-16-1416) (PMID:27678454)

Van Wyk, H. , Going, J., Horgan, P. and McMillan, D. C. (2017) The role of perineural invasion in predicting survival in patients with primary operable colorectal cancer: a systematic review. Critical Reviews in Oncology/Hematology, 112, pp. 11-20. (doi: 10.1016/j.critrevonc.2017.02.005) (PMID:28325252)

Watt, D., Mcsorley, S. T. , Park, J. H. , Horgan, P. G. and McMillan, D. C. (2017) A postoperative systemic inflammation score predicts short- and long-term outcomes in patients undergoing surgery for colorectal cancer. Annals of Surgical Oncology, 24(4), pp. 1100-1109. (doi: 10.1245/s10434-016-5659-4) (PMID:27822634)

Dolan, R. , MacLeod, N. J., McSorley, S. T. , Horgan, P. G. , Laird, B. and McMillan, D. C. (2017) Evaluation of Systemic Inflammation-based Prognostic Scores in Patients With Advanced Colorectal Cancer Receiving Palliative Pelvic Radiotherapy (RT). 2017 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 19-21 Jan 2017. (doi: 10.1200/jco.2017.35.4_suppl.558)

Dolan, R. , McSorley, S. T. , McMillan, D. C. and Horgan, P. G. (2017) Association of Ongoing Systemic Inflammatory Response (SIR) at Diagnosis With Lymph Node Retrieval and Node Positivity in Patients Undergoing Surgery for Colonic Cancer. 2017 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 19-21 Jan 2017. (doi: 10.1200/jco.2017.35.4_suppl.550)

Mcsorley, S. T. , Khor, B. Y., MacKJay, G. J., Horgan, P. G. and McMillan, D. C. (2017) Examination of a CRP first approach for the detection of postoperative complications in patients undergoing surgery for colorectal cancer: a pragmatic study. Medicine, 96(7), e6133. (doi: 10.1097/MD.0000000000006133) (PMID:28207541)

Khor, B. Y., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2017) The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: a cross-sectional study. International Journal of Surgery, 37, pp. 79-84. (doi: 10.1016/j.ijsu.2016.12.010) (PMID:27940290)

Dolan, R. , McLeod, N., McSorley, S. , McMillan, D. and Horgan, P. (2017) Evaluation of Systemic Inflammation Based Prognostic Scoresin Patients with Advanced Rectal Cancer Receiving Palliative Pelvicradiotherapy. International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Glasgow, UK, 03-05 May 2017.

Dolan, R. , McSorley, S. , McMillan, D. and Horgan, P. (2017) Ongoing Systemic Inflammatory Response at Diagnosis is Notassociated with Lower Lymph Node Retrieval and Higher Node Positivityin Patients Undergoing Surgery for Colonic Cancer. International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Glasgow, UK, 03-05 May 2017.

Little, C. H., Combet, E. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S.D. (2017) The role of dietary polyphenols in the moderation of the inflammatory response in early stage colorectal cancer. Critical Reviews in Food Science and Nutrition, 57(11), pp. 2310-2320. (doi: 10.1080/10408398.2014.997866)

McSorley, S. T. , Dolan, R. D. , Roxburgh, C. S.D. , McMillan, D. C. and Horgan, P. G. (2017) How and why systemic inflammation worsens quality of life in patients with advanced cancer. Expert Review of Quality of Life in Cancer Care, 2(3), pp. 167-175. (doi: 10.1080/23809000.2017.1331705)

2016

Patek, S.C., Willder, J.M., Heng, J.S., Taylor, B., Horgan, P.G. , Leung, H.Y. , Underwood, M.A. and Edwards, J. (2016) Androgen receptor phosphorylation status at serine 578 predicts poor outcome in prostate cancer patients. Oncotarget, 8(3), pp. 4875-4887. (doi: 10.18632/oncotarget.13608) (PMID:27902483)

Mansouri, D. , McMillan, D. C. , McIlveen, E., Crighton, E. M., Morrison, D. and Horgan, P. G. (2016) A comparison of tumour and host prognostic factors in screen-detected versus non screen-detected colorectal cancer: a contemporaneous study. Colorectal Disease, 18(10), pp. 967-975. (doi: 10.1111/codi.13295) (PMID:26859503)

Roseweir, A. K. , Powell, A. G.M.T., Bennett, L., Van Wyk, H. C. , Park, J. , McMillan, D. C. , Horgan, P. G. and Edwards, J. (2016) Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer. Oncotarget, 7(43), pp. 70601-70612. (doi: 10.18632/oncotarget.12134) (PMID:27661110)

McSorley, S. T. , Watt, D. G., Horgan, P. G. and McMillan, D. C. (2016) Postoperative systemic inflammatory response, complication severity, and survival following surgery for colorectal cancer. Annals of Surgical Oncology, 23(9), pp. 2832-2840. (doi: 10.1245/s10434-016-5204-5) (PMID:27016295) (PMCID:PMC4972846)

van Wyk, H. C. , Park, J. H. , Edwards, J. , Horgan, P. G. , McMillan, D. C. and Going, J. J. (2016) The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer. British Journal of Cancer, 115(2), pp. 156-163. (doi: 10.1038/bjc.2016.173) (PMID:27299960)

Mansouri, D. , Powell, A., Park, J. H. , McMillan, D. C. and Horgan, P. G. (2016) Long-term follow-up of patients undergoing resection of tnm stage i colorectal cancer: an analysis of tumour and host determinants of outcome. World Journal of Surgery, 40(6), pp. 1485-1491. (doi: 10.1007/s00268-016-3443-z) (PMID:26920405)

Park, J. H. , McMillan, D. C. , Edwards, J. , Horgan, P. G. and Roxburgh, C. S.D. (2016) Comparison of the prognostic value of measures of the tumor inflammatory cell infiltrate and tumor-associated stroma in patients with primary operable colorectal cancer. OncoImmunology, 5(3), e1098801. (doi: 10.1080/2162402X.2015.1098801)

Park, J. H. , Watt, D. G., Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2016) Colorectal cancer, systemic inflammation, and outcome: staging the tumor and staging the host. Annals of Surgery, 263(2), pp. 326-336. (doi: 10.1097/SLA.0000000000001122) (PMID:25575264)

McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2016) The impact of the type and severity of postoperative complications on long-term outcomes following surgery for colorectal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 97, pp. 168-177. (doi: 10.1016/j.critrevonc.2015.08.013) (PMID:26330375)

McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2016) The impact of preoperative corticosteroids on the systemic inflammatory response and postoperative complications following surgery for gastrointestinal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 101, pp. 139-150. (doi: 10.1016/j.critrevonc.2016.03.011) (PMID:26997303)

Park, J. H. , Powell, A. G., Roxburgh, C. S.D. , Horgan, P. G. , McMillan, D. c. and Edwards, J. (2016) Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment. British Journal of Cancer, 114, pp. 562-570. (doi: 10.1038/bjc.2016.17) (PMID:26859693)

2015

VAN Wyk, H. C., Foulis, A., Roxburgh, C. , Orange, C., Horgan, P. and McMillan, D. (2015) Comparison of methods to identify lymphatic and blood vessel invasion and their prognostic value in patients with primary operable colorectal cancer. Anticancer Research, 35(12), pp. 6457-6463. (PMID:26637856)

Kumar, S. K., Oon, O. K., Horgan, P. and Leen, E. (2015) Early diagnosis of intrahepatic pseudoaneurysm during radiofrequency ablation using contrast-enhanced ultrasound. Malaysian Journal of Medical Sciences, 22(6), pp. 58-62. (PMID:28223887) (PMCID:PMC5295758)

Palani Velu, L. K., Steele, C. W. , Dickson, E., Carter, C. R., McKay, C. J., Horgan, P. G. , McMillan, D. C. and Jamieson, N. B. (2015) RE:nab-paclitaxel plus gemcitabine for metastatic pancreatic cancer: long-term survival from a phase III trial. Journal of the National Cancer Institute, 107(9), djv204. (doi: 10.1093/jnci/djv204) (PMID:26251329)

Watt, D. G., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2015) Enhanced recovery after surgery. Medicine, 94(36), e1286. (doi: 10.1097/md.0000000000001286) (PMCID:PMC4616657)

Mansouri, D. , McMillan, D.C. , Crearie, C., Morrison, D.S., Crighton, E.M. and Horgan, P.G. (2015) Temporal trends in mode, site and stage of presentation with the introduction of colorectal cancer screening: a decade of experience from the West of Scotland. British Journal of Cancer, 113, pp. 556-561. (doi: 10.1038/bjc.2015.230) (PMID:26158422)

McSorley, S. T. , Ramanathan, M., Horgan, P. and McMillan, D. (2015) Postoperative C-reactive protein measurement predicts the severity of complications following surgery for colorectal cancer. International Journal of Colorectal Disease, 30(7), pp. 913-917. (doi: 10.1007/s00384-015-2229-3) (PMID:25922147)

Watt, D. G., Martin, J. C., Park, J. H. , Horgan, P. G. and McMillan, D. C. (2015) Neutrophil count is the most important prognostic component of the differential white cell count in patients undergoing elective surgery for colorectal cancer. American Journal of Surgery, 210(1), pp. 24-30. (doi: 10.1016/j.amjsurg.2014.12.031) (PMID:25842358)

McSorley, S. T. , Watt, D. G., Horgan, P. G. and McMillan, D. C. (2015) 868 Complication type and severity have an adverse effect on long-term oncological outcome following surgery for colorectal cancer. Gastroenterology, 148(4), S-1122. (doi: 10.1016/S0016-5085(15)33823-3)

Watt, D. G., Horgan, P. G. and McMillan, D. C. (2015) Comment on 'prognostic performance of inflammation-based prognostic indices in patients with resectable colorectal liver metastases'. Medical Oncology, 32(5), (doi: 10.1007/s12032-015-0617-8) (PMID:25904501)

Watt, D. G., McSorley, S. T. , Park, J. H. , Horgan, P. G. and McMillan, D. C. (2015) 879 The validation of C-reactive protein and albumin as predictors of post-operative infective complications and their clinical utility in patients with colorectal cancer. Gastroenterology, 148(4), S-1125. (doi: 10.1016/S0016-5085(15)33834-8)

Watt, D. G., Park, J. H. , Ramanathan, M. L., Horgan, P. G. and McMillan, D. C. (2015) Tu1760 neutrophil count, but not other components of a white cell count, reflects the impact of the systemic inflammatory response and long term survival in patients following elective surgery for colorectal cancer. Gastroenterology, 148(4), S-1175. (doi: 10.1016/S0016-5085(15)34008-7)

Ramanathan, M. L., Mackay, G., Platt, J., Horgan, P. G. and McMillan, D. C. (2015) The impact of open versus laparoscopic resection for colon cancer on C-reactive protein concentrations as a predictor of postoperative infective complications. Annals of Surgical Oncology, 22(3), pp. 938-943. (doi: 10.1245/s10434-014-4065-z) (PMID:25201503)

Park, J. H. , McMillan, D. C. , Powell, A. G., Richards, C. H., Horgan, P. G. , Edwards, J. and Roxburgh, C. S.D. (2015) Evaluation of a tumor microenvironment-based prognostic score in primary operable colorectal cancer. Clinical Cancer Research, 21(4), pp. 882-888. (doi: 10.1158/1078-0432.CCR-14-1686) (PMID:25473000)

van Wyk, H.C. , Park, J. , Roxburgh, C. , Horgan, P. , Foulis, A. and McMillan, D. C. (2015) The role of tumour budding in predicting survival in patients with primary operable colorectal cancer: a systematic review. Cancer Treatment Reviews, 41(2), pp. 151-159. (doi: 10.1016/j.ctrv.2014.12.007) (PMID:25549950)

Watt, D. G., Horgan, P. G. and McMillan, D. C. (2015) Routine clinical markers of the magnitude of the systemic inflammatory response after elective operation: a systematic review. Surgery, 157(2), pp. 362-380. (doi: 10.1016/j.surg.2014.09.009) (PMID:25616950)

Grivennikov, S., Watt, D. G., Proctor, M. J., Park, J. H. , Horgan, P. G. and McMillan, D. C. (2015) The Neutrophil-Platelet Score (NPS) predicts survival in primary operable colorectal cancer and a variety of common cancers. PLoS ONE, 10(11), e0142159. (doi: 10.1371/journal.pone.0142159) (PMID:26544968) (PMCID:PMC4636235)

Mansouri, D. , Park, J.H. , Orange, C., Crighton, E.M., Horgan, P.G. and McMillan, D.C. (2015) Changes in the Inflammatory Microenvironment in Premalignant Colonic Adenomatous Polyps: Evidence for Immunosurveillance? Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 535. (doi: 10.1200/jco.2015.33.3_suppl.535)

Park, J.H. , Mansouri, D. , Orange, C., Horgan, P.G. and McMillan, D.C. (2015) Assessment of the Tumor Inflammatory Cell Infiltrate in Preoperative Colonoscopic Biopsies of Patients with Primary Operable Colorectal Cancer. Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 637. (doi: 10.1200/jco.2015.33.3_suppl.637)

Park, J.H. , McMillan, D.C. , Horgan, P.G. and Roxburgh, C.S.D. (2015) The Clinical Utility of a Tumour Microenvironment-based Histopathological Score in Patients with Primary Operable Colorectal Cancer. Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 664. (doi: 10.1200/jco.2015.33.3_suppl.664)

Proctor, M., McMillan, D. C. , Horgan, P. G. , Fletcher, C. D., Talwar, D. and Morrison, D. S. (2015) Systemic inflammation predicts all-cause mortality: a Glasgow Inflammation Outcome Study. PLoS ONE, 10(3), e0116206. (doi: 10.1371/journal.pone.0116206) (PMID:25730322) (PMCID:PMC4346265)

Watt, D.G., Park, J.H. , Horgan, P.G. and McMillan, D.C. (2015) The Relationship Between Red Cell Distribution Width (RDW), Markers of Systemic Inflammation and Survival in Patients Undergoing Curative Surgery for Colorectal Cancer. Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 589. (doi: 10.1200/jco.2015.33.3_suppl.589)

Watt, D.G., Park, J.H. , Ramanathan, M.L., Horgan, P.G. and McMillan, D.C. (2015) Pre-and Postoperative Inflammatory Response to Predict Survival in Patients Undergoing Potentially Curative Resection for Colorectal Cancer. Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 609. (doi: 10.1200/jco.2015.33.3_suppl.609)

Watt, D., Roxburgh, C. , White, M., Chan, J., Horgan, P. and McMillan, D. (2015) A survey of attitudes towards the clinical application of systemic inflammation based prognostic scores in cancer. Mediators of Inflammation, 2015, 842070. (doi: 10.1155/2015/842070) (PMID:26504363) (PMCID:PMC4609481)

2014

Oliphant, R., Nicholson, G. A., Horgan, P. G. , McMillan, D. C. and Morrison, D. S. (2014) The impact of surgical specialisation on survival following elective colon cancer surgery. International Journal of Colorectal Disease, 29(9), pp. 1143-1150. (doi: 10.1007/s00384-014-1965-0) (PMID:25034593)

Roxburgh, C. S. D. , McMillan, D. C. , Richards, C. H., Atwan, M., Anderson, J., Harvey, T., Horgan, P. G. and Foulis, A. K. (2014) The clinical utility of the combination of T stage and venous invasion to predict survival in patients undergoing surgery for colorectal cancer. Annals of Surgery, 259(6), pp. 1156-1165. (doi: 10.1097/SLA.0000000000000229)

Oliphant, R., Mansouri, D. , Nicholson, G. A., McMillan, D. C. , Horgan, P. G. and Morrison, D. S. (2014) Emergency presentation of node-negative colorectal cancer treated with curative surgery is associated with poorer short and longer-term survival. International Journal of Colorectal Disease, 29(5), pp. 591-598. (doi: 10.1007/s00384-014-1847-5) (PMID:24651957)

Johnstone, M.S. et al. (2014) The accuracy of colonoscopic localisation of colorectal tumours: a prospective, multi-centred observational study. Scottish Medical Journal, 59(2), pp. 85-90. (doi: 10.1177/0036933014529051) (PMID:24659380)

van Wyk, H. C. , Roxburgh, C. S. , Horgan, P. G. , Foulis, A. F. and McMillan, D. C. (2014) The detection and role of lymphatic and blood vessel invasion in predicting survival in patients with node negative operable primary colorectal cancer. Critical Reviews in Oncology/Hematology, 90(1), pp. 77-90. (doi: 10.1016/j.critrevonc.2013.11.004) (PMID:24332522)

Forrester, R., Guthrie, G.J.K., Orange, C., Horgan, P.G. , McMillan, D.C. and Roxburgh, C.S.D. (2014) Comparison of visual and automated assessment of tumour inflammatory infiltrates in patients with colorectal cancer. European Journal of Cancer, 50(3), pp. 544-552. (doi: 10.1016/j.ejca.2013.11.003) (PMID:24332571)

Park, J.H. , McMillan, D.C. , Horgan, P.G. and Roxburgh, C.S. (2014) The impact of anti-inflammatory agents on the outcome of patients with colorectal cancer. Cancer Treatment Reviews, 40(1), pp. 68-77. (doi: 10.1016/j.ctrv.2013.05.006)

Elsberger, B., Roxburgh, C. S. and Horgan, P. G. (2014) Is there a role for surgical resections of hepatic breast cancer metastases? Hepato-Gastroenterology, 61(129), pp. 181-186. (PMID:24895817)

Oliphant, R., Horgan, P. G. , Morrison, D. S. and McMillan, D. C. (2014) Validation of a modified clinical risk score to predict cancer-specific survival for stage II colon cancer. Cancer Medicine, (doi: 10.1002/cam4.352)

Park, J.H. , Richards, C.H., McMillan, D.C. , Horgan, P.G. and Roxburgh, C.S.D. (2014) The relationship between tumour stroma percentage, the tumour microenvironment and survival in patients with primary operable colorectal cancer. Annals of Oncology, 25(3), pp. 644-651. (doi: 10.1093/annonc/mdt593)

Richards, C. H., Roxburgh, C. S.D. , Powell, A. G., Foulis, A. K., Horgan, P. G. and McMillan, D. C. (2014) The clinical utility of the local inflammatory response in colorectal cancer. European Journal of Cancer, 50(2), pp. 309-319. (doi: 10.1016/j.ejca.2013.09.008) (PMID:24103145)

2013

Powell, A.G.M.T., Ferguson, J., Al-Mulla, F., Orange, C., McMillan, D.C. , Horgan, P.G. , Edwards, J. and Going, J.J. (2013) The relationship between genetic profiling, clinicopathological factors and survival in patients undergoing surgery for node-negative colorectal cancer: 10-year follow-up. Journal of Cancer Research and Clinical Oncology, 139(12), pp. 2013-2020. (doi: 10.1007/s00432-013-1521-2)

Mansouri, D. , McMillan, D.C. , Roxburgh, C.S.D. , Moug, S.J., Crighton, E.M. and Horgan, P.G. (2013) Flexible sigmoidoscopy following a positive faecal occult blood test within a bowel screening programme may reduce the detection of neoplasia. Colorectal Disease, 15(11), pp. 1375-1381. (doi: 10.1111/codi.12377)

Ramanathan, M.L., MacKay, G., Platt, J., Horgan, P.G. and McMillan, D.C. (2013) Impact of day 2 C-reactive protein on day 3 and 4 thresholds associated with infective complications following curative surgery for colorectal cancer. World Journal of Surgery, 37(11), pp. 2705-2710. (doi: 10.1007/s00268-013-2177-4)

Guthrie, G.J.K., Charles, K.A., Roxburgh, C.S.D. , Horgan, P.G. , McMillan, D.C. and Clarke, S.J. (2013) The systemic inflammation-based neutrophil–lymphocyte ratio: experience in patients with cancer. Critical Reviews in Oncology/Hematology, 88(1), pp. 218-230. (doi: 10.1016/j.critrevonc.2013.03.010)

McMillan, D.C. and Horgan, P.G. (2013) Preoperative indicators of the systemic inflammatory response in the treatment of patients with gastrointestinal cancer. British Journal of Surgery, 100(10), pp. 1260-1.

Oliphant, R., Nicholson, G.A., Horgan, P. , Molloy, R.G., McMillan, D. and Morrison, D. (2013) Contribution of surgical specialization to improved colorectal cancer survival. British Journal of Surgery, 100(10), pp. 1388-1395. (doi: 10.1002/bjs.9227)

Mansouri, D. , McMillan, D.C. , Crighton, E.M. and Horgan, P.G. (2013) Comment on Luoet et al.: diabetes mellitus and the incidence and mortality of colorectal cancer: a meta-analysis of 24 cohort studies. Colorectal Disease, 15(8), p. 1045. (doi: 10.1111/codi.12280)

Proctor, M.J., Horgan, P.G. , Talwar, D., Fletcher, C.D., Morrison, D.S. and McMillan, D.C. (2013) Optimization of the systemic inflammation-based Glasgow prognostic score. Cancer, 119(12), pp. 2325-2332. (doi: 10.1002/cncr.28018)

Mansouri, D. , McMillan, D.C. , Crighton, E. and Horgan, P.G. (2013) Screening for colorectal cancer: what is the impact on the determinants of outcome? Critical Reviews in Oncology/Hematology, 85(3), pp. 342-349. (doi: 10.1016/j.critrevonc.2012.08.006)

Guthrie, G.J.K., Roxburgh, C.S.D. , Horgan, P.G. and McMillan, D.C. (2013) Does interleukin-6 link explain the link between tumour necrosis, local and systemic inflammatory responses and outcome in patients with colorectal cancer? Cancer Treatment Reviews, 39(1), pp. 89-96. (doi: 10.1016/j.ctrv.2012.07.003)

Willder, J.M. et al. (2013) Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients. British Journal of Cancer, 108(1), pp. 139-148. (doi: 10.1038/bjc.2012.480)

Guthrie, G.J.K., Roxburgh, C.S.D. , Farhan-Alanie, O.M., Horgan, P.G. and McMillan, D.C. (2013) Comparison of the prognostic value of longitudinal measurements of systemic inflammation in patients undergoing curative resection of colorectal cancer. British Journal of Cancer, 109(1), pp. 24-28. (doi: 10.1038/bjc.2013.330)

Guthrie, G.J.K., Roxburgh, C.S.D. , Richards, C.H., Horgan, P.G. and McMillan, D.C. (2013) Circulating IL-6 concentrations link tumour necrosis and systemic and local inflammatory responses in patients undergoing resection for colorectal cancer. British Journal of Cancer, 109(1), pp. 131-137. (doi: 10.1038/bjc.2013.291)

Mansouri, D. , McMillan, D.C. , Grant, Y., Crighton, E.M. and Horgan, P.G. (2013) The impact of age, sex and socioeconomic deprivation on outcomes in a colorectal cancer screening programme. PLoS ONE, 8(6), e66063. (doi: 10.1371/journal.pone.0066063) (PMID:23776606) (PMCID:PMC3680425)

Mansouri, D. , McMillan, D.C. , Roxburgh, C.S.D. , Crighton, E.M. and Horgan, P.G. (2013) The impact of aspirin, statins and ACE-inhibitors on the presentation of colorectal neoplasia in a colorectal cancer screening programme. British Journal of Cancer, 109(1), pp. 249-256. (doi: 10.1038/bjc.2013.292)

Oliphant, R., Nicholson, G. A., Horgan, P. G. , Molloy, R. G., McMillan, D. C. and Morrison, D. S. (2013) Deprivation and colorectal cancer surgery: longer-term survival inequalities are due to differential postoperative mortality between socioeconomic groups. Annals of Surgical Oncology, 20(7), pp. 2132-2139. (doi: 10.1245/s10434-013-2959-9)

Ramanathan, M.L., Roxburgh, C.S.D. , Guthrie, G.J.K., Orange, C., Talwar, D., Horgan, P.G. and McMillan, D.C. (2013) Is Perioperative systemic inflammation the result of insufficient cortisol production in patients with colorectal cancer? Annals of Surgical Oncology, 20(7), pp. 2172-2179. (doi: 10.1245/s10434-013-2943-4)

Roxburgh, C.S. , Richards, C.H., MacDonald, A.I., Powell, A.G., McGlynn, L.M., McMillan, D.C. , Horgan, P.G. , Edwards, J. and Shiels, P.G. (2013) The in situ local immune response, tumour senescence and proliferation in colorectal cancer. British Journal of Cancer, 109(8), pp. 2207-2216. (doi: 10.1038/bjc.2013.556)

2012

Powell, A.G., Wallace, R., McKee, R.F., Anderson, J.H., Going, J.J., Edwards, J. and Horgan, P.G. (2012) The relationship between tumour site, clinicopathological characteristics and cancer-specific survival in patients undergoing surgery for colorectal cancer. Colorectal Disease, 14(12), pp. 1493-1499. (doi: 10.1111/j.1463-1318.2012.03048.x)

Proctor, M.J., McMillan, D.C. , Morrison, D.S., Fletcher, C.D., Horgan, P.G. and Clarke, S.J. (2012) A derived neutrophil to lymphoctye ratio predicts survival in patients with cancer. British Journal of Cancer, 107(4), pp. 695-699. (doi: 10.1038/bjc.2012.292)

Leung, E. Y.L. , Roxburgh, C. S. , Talwar, D., O'Reilly, D. S., McKee, R. F., Horgan, P. G. and McMillan, D. C. (2012) The relationships between plasma and red cell vitamin B2 and B6 concentrations and the systemic and local inflammatory responses in patients with colorectal cancer. Nutrition and Cancer, 64(4), pp. 515-520. (doi: 10.1080/01635581.2012.661512) (PMID:22439733)

Nicholson, G.A., Morrison, D.S., Finlay, I.G., Diament, R.H., Horgan, P.G. and Molloy, R.G. (2012) Quality of care in rectal cancer surgery. Exploring influencing factors in the West of Scotland. Colorectal Disease, 14(6), pp. 731-739. (doi: 10.1111/j.1463-1318.2011.02754.x)

Powell, A.G.M.T., Edwards, J. and Horgan, P.G. (2012) A move towards individualisation of patient treatment regimens in colorectal cancer. Colorectal Disease, 14(2), pp. 255-256. (doi: 10.1111/j.1463-1318.2011.02818.x)

Richards, C.H., Roxburgh, C.S.D. , Anderson, J.H., McKee, R.F., Foulis, A.K., Horgan, P.G. and McMillan, D.C. (2012) Prognostic value of tumour necrosis and host inflammatory responses in colorectal cancer. British Journal of Surgery, 99(2), pp. 287-294. (doi: 10.1002/bjs.7755)

Dutta, S., Going, J.J., Crumley, A.B.C., Mohammed, Z., Orange, C., Edwards, J. , Fullarton, G.M., Horgan, P.G. and McMillan, D.C. (2012) The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma. British Journal of Cancer, 106(4), pp. 702-710. (doi: 10.1038/bjc.2011.610)

Platt, J.J., Ramanathan, M.L., Crosbie, R.A., Anderson, J.H., McKee, R.F., Horgan, P.G. and McMillan, D.C. (2012) C-reactive protein as a predictor of postoperative infective complications after curative resection in patients with colorectal cancer. Annals of Surgical Oncology, 19(13), pp. 4168-4177. (doi: 10.1245/s10434-012-2498-9)

Powell, A.G.M.T., Edwards, J. and Horgan, P.G. (2012) A move towards individualization of patient treatment regimens in colorectal cancer. Colorectal Disease, 14(2), pp. 255-256. (doi: 10.1111/j.1463-1318.2011.02818.x)

Powell, A.G.M.T., Horgan, P.G. and Edwards, J. (2012) The bodies fight against cancer: is human leucocyte antigen (HLA) class 1 the key? Journal of Cancer Research and Clinical Oncology, 138(5), pp. 723-728. (doi: 10.1007/s00432-012-1192-4)

Qayyum, T. et al. (2012) The interrelationships between Src, Cav-1 and RhoGD12 in transitional cell carcinoma of the bladder. British Journal of Cancer, 106(6), pp. 1187-1195. (doi: 10.1038/bjc.2012.52)

Qayyum, T. et al. (2012) Abstracts of the 10th International Kidney Cancer Symposium: The role of Src kinase in renal cell cancer. BJU International, 109(S5), p. 10. (doi: 10.1111/j.1464-410X.2012.11171.x)

Qayyum, T., McArdle, P.A., Lamb, G.W., Going, J.J., Horgan, P.G. , Oades, G., Aitchison, M.A. and Edwards, J. (2012) Prospective study of the role of inflammation in renal cancer. Urologia Internationalis, 88(3), pp. 277-281. (doi: 10.1159/000334971)

Qayyum, T. et al. (2012) Expression and prognostic significance of Src family members in renal clear cell carcinoma. British Journal of Cancer, 107(5), pp. 856-863. (doi: 10.1038/bjc.2012.314)

Richards, C.H., Flegg, K.M., Roxburgh, C.S.D. , Going, J.J., Mohammed, Z., Horgan, P.G. and McMillan, D.C. (2012) The relationships between cellular components of the peritumoural inflammatory response, clinicopathological characteristics and survival in patients with primary operable colorectal cancer. British Journal of Cancer, 106(12), pp. 2010-2015. (doi: 10.1038/bjc.2012.211)

Roxburgh, C.S.D. , Richards, C.H., Moug, S.J., Foulis, A.K., McMillan, D.C. and Horgan, P.G. (2012) Determinants of short- and long-term outcome in patients undergoing simultaneous resection of colorectal cancer and synchronous colorectal liver metastases. International Journal of Colorectal Disease, 27(3), pp. 363-369. (doi: 10.1007/s00384-011-1339-9)

2011

Proctor, M.J., Morrison, D.S., Talwar, D., Balmer, S.M., Fletcher, C.D., O’Reilly, D.S.J., Foulis, A.K., Horgan, P.G. and McMillan, D.C. (2011) A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study. European Journal of Cancer, 47(17), pp. 2633-2641. (doi: 10.1016/j.ejca.2011.03.028)

Maxwell, F., McGlynn, L.M., Muir, H.C., Talwar, D., Benzeval, M., Robertson, T., Roxburgh, C.S., McMillan, D. , Horgan, P.G. and Shiels, P. (2011) Telomere attrition and decreased Fetuin A levels indicate accelerated biological ageing and are implicated in the pathogenesis of colorectal cancer. Clinical Cancer Research, 17(17), pp. 5573-5581. (doi: 10.1158/1078-0432.CCR-10-3271)

Dutta, S., Crumley, A.B.C., Fullarton, G.M., Horgan, P. and McMillan, D. (2011) Comparison of the prognostic value of tumour- and patient-related factors in patients undergoing potentially curative resection of oesophageal cancer. World Journal of Surgery, 35(8), pp. 1861-1866. (doi: 10.1007/s00268-011-1130-7)

Nicholson, G. A., Finlay, I. G., Diament, R. H., Molloy, R. G., Horgan, P.G. and Morrison, D. S. (2011) Mechanical bowel preparation does not influence outcomes following colonic cancer resection. British Journal of Surgery, 98(6), pp. 866-871. (doi: 10.1002/bjs.7454)

Roxburgh, C., McDonald, A., Salmond, J., Oien, K. , Anderson, J., McKee, R., Horgan, P. and McMillan, D. (2011) Adjuvant chemotherapy for resected colon cancer: comparison of the prognostic value of tumour and patient related factors. International Journal of Colorectal Disease, 26(4), pp. 483-492. (doi: 10.1007/s00384-010-1120-5)

Roxburgh, C.S.D., Platt, J.J., Leitch, E.F., Kinsella, J., Horgan, P.G. and McMillan, D.C. (2011) Relationship between preoperative comorbidity, systemic inflammatory response, and survival in patients undergoing curative resection for colorectal cancer. Annals of Surgical Oncology, 18(4), pp. 997-1005. (doi: 10.1245/s10434-010-1410-8)

Dutta, S., Al-Mrabt, N.M., Fullarton, G.M., Horgan, P.G. and McMillan, D.C. (2011) A comparison of POSSUM and GPS models in the prediction of post-operative outcome in patients undergoing oesophago-gastric cancer resection. Annals of Surgical Oncology, 18(10), pp. 2808-2817. (doi: 10.1245/s10434-011-1676-5)

Dutta, S., Fullarton, G.M., Forshaw, M.J., Horgan, P.G. and McMillan, D.C. (2011) Persistent Elevation of C-Reactive Protein Following Esophagogastric Cancer Resection as a Predictor of Postoperative Surgical Site Infectious Complications. World Journal of Surgery, 35(5), pp. 1017-1025. (doi: 10.1007/s00268-011-1002-1)

Proctor, M.J., Morrison, D.S., Talwar, D., Balmer, S.M., O'Reilly, D.S.J., Foulis, A.K., Horgan, P.G. and McMillan, D.C. (2011) An inflammation-based prognostic score (mGPS) predicts cancer survival independent of tumour site: a Glasgow Inflammation Outcome Study. British Journal of Cancer, 104(4), pp. 726-734. (doi: 10.1038/sj.bjc.6606087)

Richards, C.H., Leitch, E.F., Anderson, J.H., McKee, R.F., McMillan, D.C. and Horgan, P.G. (2011) The revised ACPGBI model is a simple and accurate predictor of operative mortality after potentially curative resection of colorectal cancer. Annals of Surgical Oncology, 18(13), pp. 3680-3685. (doi: 10.1245/s10434-011-1805-1)

Richards, C.H., Platt, J.J., Anderson, J.H., McKee, R.F., Horgan, P.G. and McMillan, D.C. (2011) The Impact of Perioperative Risk, Tumor Pathology and Surgical Complications on Disease Recurrence After Potentially Curative Resection of Colorectal Cancer. Annals of Surgery, 254(1), pp. 83-89. (doi: 10.1097/SLA.0b013e31821fd469)

2010

Roxburgh, C.S.D., McMillan, D.C. , Anderson, J.H., McKee, R.F., Horgan, P.G. and Foulis, A.K. (2010) Elastica staining for venous invasion results in superior prediction of cancer specific survival in colorectal cancer. Annals of Surgery, 252(6), pp. 989-997. (doi: 10.1097/SLA.0b013e3181f1c60d)

Roxburgh, C.S.D. , Wallace, A.M., Guthrie, G., Horgan, P.G. and McMillan, D.C. (2010) Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer. Colorectal Disease, 12(10), pp. 987-994. (doi: 10.1111/j.1463-1318.2009.01961.x) (PMID:19555389)

Moug, S.J., Smith, D., Leen, E., Roxburgh, C. and Horgan, P.G. (2010) Evidence for a synchronous operative approach in the treatment of colorectal cancer with hepatic metastases: a case matched study. European Journal of Surgical Oncology, 36(4), pp. 365-370. (doi: 10.1016/j.ejso.2009.11.007)

Dutta, S., Horgan, P.G. and McMillan, D.C. (2010) POSSUM and its related models as predictors of postoperative mortality and morbidity in patients undergoing surgery for gastro-oesophageal cancer: a systematic review. World Journal of Surgery, 34(9), pp. 2076-2082. (doi: 10.1007/s00268-010-0685-z)

Horgan, P.G. and McMillan, D.C. (2010) Surgeons and selection of adjuvant therapy for node-negative colonic cancer. British Journal of Surgery, 97(10), pp. 1459-1460. (doi: 10.1002/bjs.7254)

Leung, E.Y.L. , Roxburgh, C.S.D. , Leen, E. and Horgan, P. G. (2010) Combined resection and radiofrequency ablation for bilobar colorectal cancer liver metastases. Hepato-Gastroenterology, 57(97), pp. 41-46. (PMID:20422869)

Proctor, M. J., Talwar, D., Balmar, S. M., O'Reilly, D. S. J., Foulis, A. K., Horgan, P.G. , Morrison, D. S. and McMillan, D. C. (2010) The relationship between the presence and site of cancer, an inflammation-based prognostic score and biochemical parameters. Initial results of the Glasgow Inflammation Outcome Study. British Journal of Cancer, 103(6), pp. 870-876. (doi: 10.1038/sj.bjc.6605855)

Richards, C.H., Leitch, E.F., Horgan, P.G. , Anderson, J., McKee, R.F. and McMillan, D.C. (2010) The relationship between patient physiology, the systemic inflammatory response and survival in patients undergoing curative resection of colorectal cancer. British Journal of Cancer, 103(9), pp. 1356-1361. (doi: 10.1038/sj.bjc.6605919)

Richards, C.H., Leitch, F.E., Horgan, P.G. and McMillan, D.C. (2010) A Systematic Review of POSSUM and its Related Models as Predictors of Post-operative Mortality and Morbidity in Patients Undergoing Surgery for Colorectal Cancer. Journal of Gastrointestinal Surgery, 14(10), pp. 1511-1519. (doi: 10.1007/s11605-010-1333-5)

2009

Roxburgh, C.S., Salmond, J.M., Horgan, P.G., Oien, K.A. and McMillan, D.C. (2009) Tumour inflammatory infiltrate predicts survival following curative resection for node-negative colorectal cancer. European Journal of Cancer, 45(12), pp. 2138-2145. (doi: 10.1016/j.ejca.2009.04.011)

Roxburgh, C.S.D., Salmond, J.M., Horgan, P.G. , Oien, K.A. and McMillan, D.C. (2009) Comparison of the prognostic value of inflammation based pathological and biochemical criteria in patients undergoing potentially curative resection for colorectal cancer. Annals of Surgery, 249(5), pp. 788-793. (doi: 10.1097/SLA.0b013e3181a3e738)

Roxburgh, C.S.D., Salmond, J.M., Horgan, P.G. , Oien, K.A. and McMillan, D.C. (2009) The relationship between the local and systemic inflammatory responses and survival in patients undergoing curative surgery for colon and rectal cancers. Journal of Gastrointestinal Surgery, 13(11), pp. 2011-2019. (doi: 10.1007/s11605-009-1034-0)

2008

Leung, E.Y.L. , Crozier, J.E.M., Talwar, D., O'Reilly, D.S.J., McKee, R.F., Horgan, P.G. and McMillan, D.C. (2008) Vitamin antioxidants, lipid peroxidation, tumour stage, the systemic inflammatory response and survivial in patients with colorectal cancer. International Journal of Cancer, 123(10), pp. 2460-2464. (doi: 10.1002/ijc.23811) (PMID:18729200)

Leung, E.Y.L. , Roxburgh, C.S.D., Leen, E. and Horgan, P.G. (2008) Combined resection and radiofrequency ablation for bilobar liver metastases. European Journal of Surgical Oncology, 34(10), p. 1168. (doi: 10.1016/j.ejso.2008.06.062)

2007

Crozier, J.E., McMillan, D.C., McArdle, C.S., Angerson, W.J., Anderson, J.H., Horgan, P. and McKee, R.F. (2007) Tumor size is associated with the systemic inflammatory response but not survival in patients with primary operable colorectal cancer. Journal of Gastroenterology and Hepatology, 22(12), pp. 2288-2291. (doi: 10.1111/j.1440-1746.2006.04792.x)

Horgan, P. (2007) Selective continuous vascular occlusion and perioperative fluid restriction in partial hepatectomy. Outcomes in 101 consecutive patients. European Journal of Surgical Oncology, 33(8), pp. 1036-1041. (doi: 10.1016/j.ejso.2007.01.028)

Crozier, J.E.M., McKee, R.F., McArdle, C.S., Angerson, W.J., Anderson, J.H., Horgan, P. and McMillan, D.C. (2007) Preoperative but not postoperative systemic inflammatory response correlates with survival in colorectal cancer. British Journal of Surgery, 94(8), pp. 1028-1032. (doi: 10.1002/bjs.5706)

Ceccotti, P., Horgan, P. , Leen, E. and Moug, S. (2007) Contrast-enhanced intraoperative ultrasonography: A valuable and not any more monocentric diagnostic technique performed in different ways - Reply. Annals of Surgery, 245(1), pp. 152-153. (doi: 10.1097/00000658-200701000-00024)

Horgan, P. (2007) Metastatic colorectal cancer. Surgical Oncology: Oxford, 16(1), p. 1.

Horgan, P.G. and Leen, E. (2007) Radiofrequency ablation of colorectal liver metastases. Surgical Oncology: Oxford, 16, pp. 47-51. (doi: 10.1016/j.suronc.2007.04.004)

Horgan, P.G. and Moug, S.J. (2007) The role of synchronous procedures in the treatment of colorectal liver metastases. Surgical Oncology: Oxford, 16, pp. 53-58. (doi: 10.1016/j.suronc.2007.04.005)

Leitch, E.F., Chakrabarti, M., Crozier, J.E.M., McKee, R.F., Anderson, J.H., Horgan, P. and McMillan, D.C. (2007) Comparison of the prognostic value of selected markers of the systemic inflammatory response in patients with colorectal cancer. British Journal of Cancer, 97(9), pp. 1266-1270.

2006

Moug, S.J., Smith, D., Wilson, I.S., Leen, E. and Horgan, P.G. (2006) The renal sequelae of a novel triphasic approach to blood loss reduction during hepatic resection. European Journal of Surgical Oncology, 32(4), pp. 435-438. (doi: 10.1016/j.ejso.2006.01.011) (PMID:16520017)

Alani, A., Duffy, F., Horgan, P., Norrie, J., O'Dwyer, P. and Walker, A. (2006) Observation or operation for patients with an asymptomatic inguinal hernia - A randomized clinical trial. Annals of Surgery, 244, pp. 167-173. (doi: 10.1097/01.sla.0000217637.69699.ef)

Ceccotti, P.C., Horgan, P. , Kalogeropoulou, C.P. and Leen, E. (2006) Is contrast enhanced ultrasound an essential tool for liver trauma? Journal of Trauma-Injury Infection and Critical Care, 60, pp. 233-236. (doi: 10.1097/01.ta.0000200843.80420.28)

Crozier, J., McKee, R., McArdle, C., Angerson, W., Anderson, J. , Horgan, P. and McMillan, D. (2006) The presence of a systemic inflammatory response predicts poorer survival in patients receiving adjuvant 5-FU chemotherapy following potentially curative resection for colorectal cancer. British Journal of Cancer, 94, pp. 1833-1836. (doi: 10.1038/sj.bjc.6603185)

Horgan, P. (2006) Potential value of contrast-enhanced intraoperative ultrasonography during partial hepatectomy for metastases: an essential investigation before resection? Annals of Surgery, 243(2), pp. 236-240. (doi: 10.1097/01.sla.0000197708.77063.07)

Horgan, P. , Imrie, C., Leen, E. and Moug, S. (2006) Radiofrequency ablation has a valuable therapeutic role in metastatic VIPoma. Pancreatology, 6, pp. 155-159. (doi: 10.1159/000090257)

Leen, E., Ceccotti, P., Kalogeropoulou, C., Angerson, W., Moug, S. and Horgan, P. (2006) Prospective multicenter trial evaluating a novel method of characterizing focal liver lesions using contrast-enhanced sonography. American Journal of Roentgenology, 186, pp. 1551-1559. (doi: 10.2214/AJR.05.0138)

Leen, E. et al. (2006) Potential value of contrast-enhanced intraoperative ultrasonography during partial hepatectomy for metastases - An essential investigation before resection? Annals of Surgery, 243(2), pp. 236-240.

2005

Anderson, J. et al. (2005) Accuracy of thin section magnetic resonance using phased-array pelvic coil in predicting the T-staging of rectal cancer. European Journal of Radiology, 53(2), pp. 256-262.

Craig, S., Horgan, P. , Moug, S. and Roditi, G. (2005) Hepatobiliary and pancreatic: Extensive thrombosis in Budd-Chiari syndrome. Journal of Gastroenterology and Hepatology, 20(8), p. 1302.

Hallum, N., Horgan, P. , Moug, S. and O'Reilly, D. (2005) Cardiac troponin I predicts outcome after ruptured abdominal aortic aneurysm repair (Br J Surg 2005; 92 : 824-827). British Journal of Surgery, 92(11), p. 1454.

Moug, S., Robertson, E., Angerson, W. and Horgan, P. (2005) Socioeconomic deprivation has an adverse effect on outcome after ileostomy closure. British Journal of Surgery, 92(3), pp. 376-377.

2004

Al, S., Angerson, W., Horgan, P. , McArdle, C. and McMillan, D. (2004) The relationship between hypoalbuminaemia, tumour volume and the systemic inflammatory response in patients with colorectal liver metastases. British Journal of Cancer, 91, pp. 205-207. (doi: 10.1038/sj.bjc.6601886)

Canna, K., Horgan, P. , McArdle, C., McKee, R., McMillan, D. and McNicol, A. (2004) Evaluation of a cumulative prognostic score based on the systemic inflammatory response in patients undergoing potentially curative surgery for colorectal cancer. British Journal of Cancer, 90, pp. 1707-1709. (doi: 10.1038/sj.bjc.6601757)

Horgan, P. (2004) Contrast-enhanced ultrasonography during liver surgery (Br J Surg 2004; 91: 1165-1167). British Journal of Surgery, 91(11), p. 1527. (doi: 10.1002/bjs.4852)

Horgan, P. , Leen, E. and Moug, S. (2004) Contrast-enhanced ultrasonography during liver surgery (Br J Surg 2004; 91 : 1165-1167). British Journal of Surgery, 91(11), p. 1527.

Horgan, P. , Leen, E. and Moug, S. (2004) Potential impact and utilization of ultrasound contrast media. European Radiology, 14, P16-P24. (doi: 10.1007/s10406-004-0077-2)

2003

O'Dwyer, P.J. et al. (2003) Local or general anesthesia for open hernia repair: a randomized trial. Annals of Surgery, 237(4), pp. 574-579.

Franklin, E., Horgan, P. , Lowney, J. and Seetharam, S. (2003) Randomized, clinical trial of Ligasure (TM) vs. conventional diathermy in hemorrhoidectomy. Diseases of the Colon and Rectum, 46(10), pp. 1380-1383.

Glen, P. and Horgan, P. (2003) A simple technique for fenestration of an hepatic cyst. Annals of the Royal College of Surgeons of England, 85(3), p. 209.

Horgan, P. , Paige, J. and Seetharam, S. (2003) Impact of socioeconomic deprivation and primary pathology on rate of reversal of Hartmann's procedure. American Journal of Surgery, 186, pp. 154-157. (doi: 10.1016/S0002-9610(03)00172-7)

2002

Horgan, P. (2002) The 'half-Pringle' maneuver - Reply. American Journal of Surgery, 184(2), pp. 182-183.

Horgan, P. , Kenny, G. and Milne, S. (2002) Target-controlled infusions of propofol and remifentanil with closed-loop anaesthesia for hepatic resection. Anaesthesia, 57(1), p. 93.

2001

Horgan, P. (2001) A novel technique for parenchymal division during hepatectomy. American Journal of Surgery, 181(3), pp. 236-237.

Horgan, P. (2001) A simple technique for vascular control during hepatectomy: the half-Pringle. American Journal of Surgery, 182(3), pp. 265-267. (doi: 10.1016/S0002-9610(01)00697-3)

Horgan, P. and Leen, E. (2001) A simple technique for vascular control during hepatectomy: the half-Pringle. American Journal of Surgery, 182(3), pp. 265-267.

Horgan, P. and Quasim, T. (2001) Severe abdominal pain in women: A case report of an hepatic adenoma. Scottish Medical Journal, 46, p. 147.

Articles

Galbraith, N. J. et al. (2024) TAK1 expression is associated with increased PD-L1 and decreased cancer-specific survival in microsatellite-stable colorectal cancer. Translational Oncology, 48, 102064. (doi: 10.1016/j.tranon.2024.102064) (PMID:39068768)

Golder, A. M. , Ferguson, M., McMillan, P., Mansouri, D. , Horgan, P. G. , Roxburgh, C. S. , Dolan, R. D. , McGovern, J. and McMillan, D. (2024) CT-derived body composition and differential association with age, TNM stage and systemic inflammation in patients with colon cancer. Scientific Reports, 14, 15673. (doi: 10.1038/s41598-024-65871-y) (PMID:38977870) (PMCID:PMC11231341)

Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4)

McGovern, J., Mackay, C., Freireich, R., Golder, A. M. , Dolan, R. D. , Horgan, P. G. , Holroyd, D., Jamieson, N. B. and McMillan, D. C. (2024) The relationship between liver volume, clinicopathological characteristics and survival in patients undergoing resection with curative intent for non-metastatic colonic cancer. Tomography, 10(3), pp. 349-359. (doi: 10.3390/tomography10030027) (PMID:38535769) (PMCID:PMC10974240)

Johnstone, M. S., McSorley, S. T. , McMillan, D. C. , Horgan, P. G. and Mansouri, D. (2024) The relationship between systemic inflammatory response, screen detection and outcome in colorectal cancer. Colorectal Disease, 26(1), pp. 81-94. (doi: 10.1111/codi.16824) (PMID:38095280)

Galbraith, N. J. et al. (2023) Effect of differing flap reconstruction strategies in perineal closure following advanced pelvic oncological resection: a retrospective cohort study. International Journal of Surgery, 109(11), pp. 3375-3382. (doi: 10.1097/JS9.0000000000000617) (PMID:37678294) (PMCID:PMC10651229)

McMahon, R. K., O'Cathail, S. M. , Nair, H., Steele, C. W. , Platt, J. J., Digby, M., McDonald, A. C., Horgan, P. G. and Roxburgh, C. S.D. (2023) The neoadjuvant rectal score and a novel magnetic resonance imaging based neoadjuvant rectal score are stage independent predictors of long-term outcome in locally advanced rectal cancer. Colorectal Disease, 25(9), pp. 1783-1794. (doi: 10.1111/codi.16667) (PMID:37485654)

McGovern, J., Leadbitter, S., Miller, G., Hounat, A., Kamande, I., Dolan, R. D. , Horgan, P. G. , Chang, D. K. , Jamieson, N. B. and McMillan, D. C. (2023) The relationship between heart rate variability and TNM stage, co-morbidity, systemic inflammation and survival in patients with primary operable colorectal cancer. Scientific Reports, 13, 8157. (doi: 10.1038/s41598-023-35396-x) (PMID:37208421) (PMCID:PMC10198985)

Wood, C. S. et al. (2023) Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases. Cancer Research, 83(8), pp. 1329-1344. (doi: 10.1158/0008-5472.CAN-22-2794) (PMID:37057593) (PMCID:PMC10102851)

Alexander, P.G., van Wyk, H.C. , Pennel, K.A.F., Hay, J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S.D. , Edwards, J. and Park, J.H. (2023) The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer. British Journal of Cancer, 128(4), pp. 556-567. (doi: 10.1038/s41416-022-02069-x) (PMID:36476660) (PMCID:PMC9938140)

McGovern, J., Grayston, A., Coates, D., Leadbitter, S., Hounat, A., Horgan, P. G. , Dolan, R. D. and McMillan, D. C. (2023) The relationship between the modified frailty index score (mFI-5), malnutrition, body composition, systemic inflammation and short-term clinical outcomes in patients undergoing surgery for colorectal cancer. BMC Geriatrics, 23, 9. (doi: 10.1186/s12877-022-03703-2) (PMID:36609242) (PMCID:PMC9817261)

McGovern, J. et al. (2023) The relationship between computed tomography-derived sarcopenia, cardiopulmonary exercise testing performance, systemic inflammation, and survival in good performance status patients with oesophago-gastric cancer undergoing neoadjuvant treatment. JCSM Clinical Reports, 8(1), pp. 3-11. (doi: 10.1002/crt2.57)

Golder, A. M. , Sin, L. K. E., Alani, F., Dolan, R. , Mansouri, D. , Horgan, P. G. , McMillan, D. C. and Roxburgh, C. S. (2022) The relationship between the mode of presentation, CT-derived body composition, systemic inflammatory grade and survival in colon cancer. Journal of Cachexia, Sarcopenia and Muscle, 13(6), pp. 2863-2874. (doi: 10.1002/jcsm.13097) (PMID:36218135) (PMCID:PMC9745485)

Pennel, K. A. F. et al. (2022) CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer. Journal of Pathology: Clinical Research, 8(6), pp. 509-520. (doi: 10.1002/cjp2.290) (PMID:35879507) (PMCID:PMC9535100)

Golder, A.M. , Mshihadani, A., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and Mansouri, D. (2022) Route to diagnosis of colorectal cancer and association with survival within the context of a bowel screening programme. Public Health, 211, pp. 53-61. (doi: 10.1016/j.puhe.2022.06.032) (PMID:36027788)

McGovern, J., Dolan, R. D. , Maguire, D., Horgan, P. , Laird, B. J. and McMillan, D. C. (2022) A comparison of CT-body composition measurements in non-cancer and cancer patients from a single UK centre. Journal of Frailty, Sarcopenia and Falls, 7(3), pp. 117-122. (doi: 10.22540/JFSF-07-117) (PMID:36119551) (PMCID:PMC9433946)

Alexander, P. G. et al. (2022) The relationship between the Glasgow Microenvironment Score and markers of epithelial-mesenchymal transition in TNM II-III colorectal cancer. Human Pathology, 127, pp. 1-11. (doi: 10.1016/j.humpath.2022.05.012) (PMID:35623467)

Cheong, C. M., Golder, A. , Horgan, P. , Roxburgh, C. and McMillan, D. (2022) Relationship between pre‑operative glycated haemoglobin and surgical site infection in patients undergoing elective colon cancer surgery. Oncology Letters, 24(3), 296. (doi: 10.3892/ol.2022.13416) (PMID:35949622) (PMCID:PMC9353220)

Di Rollo, D. G., McGovern, J., Morton, C., Miller, G., Dolan, R. , Horgan, P. G. , McMillan, D. C. and Mansouri, D. (2022) Relationship between BMI, CT-derived body composition and colorectal neoplasia in a bowel screening population. Scottish Medical Journal, 67(3), pp. 93-102. (doi: 10.1177/00369330221102237) (PMID:35603880)

McGovern, J., Golder, A. M. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2022) The combination of computed tomography-derived muscle mass and muscle density and relationship with clinicopathological characteristics and survival in patients undergoing potentially curative surgery for colorectal cancer. JCSM Clinical Reports, 7(3), pp. 65-76. (doi: 10.1002/crt2.54)

Patel, M. et al. (2022) Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer. British Journal of Cancer, 126(12), pp. 1704-1714. (doi: 10.1038/s41416-022-01729-2) (PMID:35173303) (PMCID:PMC9174220)

Ross, F. A., Park, J. H. , Mansouri, D. , Combet, E. , Horgan, P. G. , McMillan, D. C. and Roxburgh, C. S.D. (2022) The role of faecal calprotectin in diagnosis and staging of colorectal neoplasia: a systematic review and meta-analysis. BMC Gastroenterology, 22, 176. (doi: 10.1186/s12876-022-02220-1) (PMID:35397505) (PMCID:PMC8994317)

McGovern, J., Dolan, R. D. , Horgan, P. G. , Laird, B. J. and McMillan, D. C. (2022) The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review. BMC Geriatrics, 22, 260. (doi: 10.1186/s12877-022-02928-5) (PMID:35351011) (PMCID:PMC8962494)

Golder, A. M. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S.D. (2022) Determinants of emergency presentation in patients with colorectal cancer: a systematic review and meta-analysis. Scientific Reports, 12, 4366. (doi: 10.1038/s41598-022-08447-y) (PMID:35288664) (PMCID:PMC8921241)

Ross, F. A., Park, J. H. , Mansouri, D. , Little, C., Di Rollo, D. G., Combet, E. , Van Wyk, H. , Horgan, P. G. , McMillan, D. C. and Roxburgh, C. S. D. (2022) The role of faecal calprotectin in the identification of colorectal neoplasia in patients attending for screening colonoscopy. Colorectal Disease, 24(2), pp. 188-196. (doi: 10.1111/codi.15942) (PMID:34614299)

Cheong, C. M., Golder, A. M. , Horgan, P. D. , McMillan, D. C. and Roxburgh, C. S.D. (2022) Evaluation of clinical prognostic variables on short-term outcome for colorectal cancer surgery: an overview and minimum dataset. Cancer Treatment and Research Communications, 31, 100544. (doi: 10.1016/j.ctarc.2022.100544) (PMID:35248885)

McGovern, J., Dolan, R. D. , Horgan, P. G. , Laird, B. J. and McMillan, D. C. (2021) Computed tomography-defined low skeletal muscle index and density in cancer patients: observations from a systematic review. Journal of Cachexia, Sarcopenia and Muscle, 12(6), pp. 1408-1417. (doi: 10.1002/jcsm.12831) (PMID:34664431) (PMCID:PMC8718024)

Knight, K. A., Drami, I., McMillan, D. C. , Horgan, P. G. , Park, J. H. , Jenkins, J. T. and Roxburgh, C. S.D. (2021) Vascular calcification and response to neoadjuvant therapy in locally advanced rectal cancer: an exploratory study. Journal of Cancer Research and Clinical Oncology, 147(11), pp. 3409-3420. (doi: 10.1007/s00432-021-03570-1) (PMID:33710416) (PMCID:PMC8484095)

Lampis, A. et al. (2021) MIR21-induced loss of junctional adhesion molecule A promotes activation of oncogenic pathways, progression and metastasis in colorectal cancer. Cell Death and Differentiation, 28, pp. 2970-2982. (doi: 10.1038/s41418-021-00820-0) (PMID:34226680) (PMCID:PMC8481293)

Johnstone, M. S., McMillan, D. C. , Horgan, P. G. and Mansouri, D. (2021) The relationship between co-morbidity, screen-detection and outcome in patients undergoing resection for colorectal cancer. World Journal of Surgery, 45(7), pp. 2251-2260. (doi: 10.1007/s00268-021-06079-3) (PMID:33774690) (PMCID:PMC8154830)

Mansouri, D. , McSorley, S. T. , Park, J. H. , Orange, C., Horgan, P. G. , McMillan, D. C. and Edwards, J. (2021) The inflammatory microenvironment in screen-detected premaligant adenomatous polyps: early results from the integrated technologies for improved polyp surveillance (INCISE) project. European Journal of Gastroenterology and Hepatology, 33(7), pp. 983-989. (doi: 10.1097/MEG.0000000000002202) (PMID:34034277)

Knight, K. A., Hon Fei, C., Boland, K. F., Dolan, D. R., Golder, A. M. , McMillan, D. C. , Horgan, P. G. , Black, D. H., Park, J. H. and Roxburgh, C. S.D. (2021) Aortic calcification is associated with non-infective rather than infective postoperative complications following colorectal cancer resection: an observational cohort study. European Radiology, 31(6), pp. 4319-4329. (doi: 10.1007/s00330-020-07189-7) (PMID:33201280)

Al-Badran, S. S.F. et al. (2021) Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 7(2), pp. 121-134. (doi: 10.1002/cjp2.193) (PMID:33338327)

Alexander, P.G. et al. (2021) The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. British Journal of Cancer, 124, pp. 786-796. (doi: 10.1038/s41416-020-01168-x) (PMID:33223535)

Alhayyan, A. M. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2021) The effect of anesthesia on the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colorectal cancer in the context of an enhanced recovery pathway: A prospective cohort study. Medicine, 100(2), e23997. (doi: 10.1097/MD.0000000000023997) (PMID:33466141) (PMCID:PMC7808526)

Knight, K., Choong, J.X., McKee, R.F., Anderson, J.H., Horgan, P.G. , McMillan, D.C. , McDonald, A. and Roxburgh, C.S. (2021) The influence of systemic inflammation on treatment response and survival in anal squamous cell cancer. Clinical Oncology, 33(1), e22-e30. (doi: 10.1016/j.clon.2020.06.010) (PMID:32709540)

Dolan, R. D. , Maclay, J. D., Abbass, T., Colville, D., Buali, F., MacLeod, N., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2020) The relationship between 18F-FDG-PETCT-derived tumour metabolic activity, nutritional risk, body composition, systemic inflammation and survival in patients with lung cancer. Scientific Reports, 10, 20819. (doi: 10.1038/s41598-020-77269-7) (PMID:33257741) (PMCID:PMC7705735)

Dolan, R. D. , Alwahid, M., McSorley, S. T. , Park, J. H. , Stevenson, R. P., Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2020) A comparison of the prognostic value of composite ratios and cumulative scores in patients with operable rectal cancer. Scientific Reports, 10, 17965. (doi: 10.1038/s41598-020-73909-0) (PMID:33087753) (PMCID:PMC7578034)

Abbass, T. , Dolan, R. D. , Horgan, P. G. and McMillan, D. C. (2020) The relationship between systemic inflammation, body composition and clinical outcomes in patients with operable colorectal cancer at low and medium to high nutritional risk. JCSM Clinical Reports, 5(4), pp. 99-107. (doi: 10.1002/crt2.25)

Roseweir, A. K. et al. (2020) Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. Journal of Pathology: Clinical Research, 6(4), pp. 283-296. (doi: 10.1002/cjp2.171) (PMID:32401426) (PMCID:PMC7578335)

Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2020) Authors' reply: Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short-term outcomes following left-sided colonic and rectal resections. BJS Open, 4(4), pp. 730-731. (doi: 10.1002/bjs5.50286) (PMID:32297454) (PMCID:PMC7397349)

Park, J. H. , Fuglestad, A. J., Køstner, A. H., Oliwa, A., Graham, J., Horgan, P. G. , Roxburgh, C. S.D. , Kersten, C. and McMillan, D. C. (2020) Systemic inflammation and outcome in 2295 patients with stage I-III colorectal cancer from Scotland and Norway: First results from the ScotScan Colorectal Cancer Group. Annals of Surgical Oncology, 27, pp. 2784-2794. (doi: 10.1245/s10434-020-08268-1) (PMID:32248375) (PMCID:PMC7334267)

Dolan, R. D. , Tien, Y.-T., Horgan, P. G. , Edwards, C. A. and McMillan, D. C. (2020) The relationship between computed tomography‐derived body composition and survival in colorectal cancer: the effect of image software. Journal of Cachexia, Sarcopenia and Muscle: Rapid Communications, 3(2), pp. 81-90. (doi: 10.1002/rco2.15)

McSorley, S. T. , Anderson, J. H., Whittle, T., Roxburgh, C. S. , Horgan, P. G. , McMillan, D. C. and Steele, C. W. (2020) The impact of preoperative systemic inflammation on the efficacy of intravenous iron infusion to correct anaemia prior to surgery for colorectal cancer. Perioperative Medicine, 9, 17. (doi: 10.1186/s13741-020-00146-4) (PMID:32537137) (PMCID:PMC7288411)

ALHAYYAN, A. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2020) The relationship between anaesthetic technique, clinicopathological characteristics and the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colon cancer. PLoS ONE, 15(4), e0228580. (doi: 10.1371/journal.pone.0228580) (PMID:32348308) (PMCID:PMC7190171)

Alhayyan, A. , McSorley, S. , Roxburgh, C. , Kearns, R. , Horgan, P. and McMillan, D. (2020) The effect of anesthesia on the postoperative systemic inflammatory response in patients undergoing surgery: a systematic review and meta-analysis. Surgery Open Science, 2(1), pp. 1-21. (doi: 10.1016/j.sopen.2019.06.001) (PMID:32754703) (PMCID:PMC7391900)

Knight, K.A., Horgan, P.G. , McMillan, D.C. , Roxburgh, C.S.D. and Park, J.H. (2020) The relationship between aortic calcification and anastomotic leak following gastrointestinal resection: a systematic review. International Journal of Surgery, 73, pp. 42-49. (doi: 10.1016/j.ijsu.2019.11.023) (PMID:31765846)

McSorley, S. T. , Tham, A., Dolan, R. D. , Steele, C. W. , Ramsingh, J., Roxburgh, C. , Horgan, P. G. and McMillan, D. C. (2020) Perioperative blood transfusion is associated with the postoperative systemic inflammatory response and poorer outcomes following surgery for colorectal cancer. Annals of Surgical Oncology, 27, pp. 833-843. (doi: 10.1245/s10434-019-07984-7) (PMID:31664621) (PMCID:PMC7000540)

Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2019) Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short‐term outcomes following left‐sided colonic and rectal resections. BJS Open, 3(6), pp. 830-839. (doi: 10.1002/bjs5.50224) (PMID:31832590) (PMCID:PMC6887908)

Golder, A. M. , McSorley, S. T. , Kearns, R. J. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S. (2019) Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: a qualitative study. Annals of Medicine and Surgery, 48, pp. 23-28. (doi: 10.1016/j.amsu.2019.10.007) (PMID:31687135) (PMCID:PMC6820077)

Almasaudi, A. S., Dolan, R. D. , McSorley, S. T. , Horgan, P. G. , Edwards, C. and McMillan, D. C. (2019) Relationship between computed tomography-derived body composition, sex, and post-operative complications in patients with colorectal cancer. European Journal of Clinical Nutrition, 73(11), pp. 1450-1457. (doi: 10.1038/s41430-019-0414-0) (PMID:30858540)

Jackstadt, R. et al. (2019) Epithelial NOTCH signaling rewires the tumor microenvironment of colorectal cancer to drive poor-prognosis subtypes and metastasis. Cancer Cell, 36(3), 319-336.e7. (doi: 10.1016/j.ccell.2019.08.003) (PMID:31526760) (PMCID:PMC6853173)

Park, J. H. , van Wyk, H. , McMillan, D. C. , Edwards, J. , Orange, C., Horgan, P. G. and Roxburgh, C. S.D. (2019) Pre-operative, biopsy-based assessment of the tumour microenvironment in patients with primary operable colorectal cancer. Journal of Pathology: Clinical Research, 6(1), pp. 30-39. (doi: 10.1002/cjp2.143) (PMID:31486287) (PMCID:PMC6966701)

Dolan, R. , Laird, B. J.A., Klepstad, P., Kaasa, S., Horgan, P. G. , Paulsen, Ø. and McMillan, D. C. (2019) An exploratory study examining the relationship between performance status and systemic inflammation frameworks and cytokine profiles in patients with advanced cancer. Medicine, 98(37), e17019. (doi: 10.1097/MD.0000000000017019) (PMID:31517821) (PMCID:PMC6750290)

McSorley, S. T. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. , MacKay, G. J. and McMillan, D. C. (2019) Possible dose dependent effect of perioperative dexamethasone and laparoscopic surgery on the postoperative systemic inflammatory response and complications following surgery for colon cancer. European Journal of Surgical Oncology, 45(9), pp. 1613-1618. (doi: 10.1016/j.ejso.2019.05.020) (PMID:31130339)

McSorley, S. T. , Tham, A., Steele, C. W. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2019) Quantitative data on red cell measures of iron status and their relation to the magnitude of the systemic inflammatory response and survival in patients with colorectal cancer. European Journal of Surgical Oncology, 45(7), pp. 1205-1211. (doi: 10.1016/j.ejso.2019.02.027) (PMID:30850153)

Roseweir, A. K. , Clark, J., McSorley, S. T. , vanWyk, H. C. , Quinn, J. A. , Horgan, P. G. , McMillan, D. C. , Park, J. H. and Edwards, J. (2019) The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer. International Journal of Cancer, 144(9), pp. 2320-2329. (doi: 10.1002/ijc.32045) (PMID:30521130)

Dolan, R. D. , McLees, N. G., Irfan, A., McSorley, S. T. , Horgan, P. G. , Colville, D. and McMillan, D. C. (2019) The relationship between tumour glucose metabolism and host systemic inflammatory responses in patients with cancer: a systematic review. Journal of Nuclear Medicine, 60(4), pp. 467-471. (doi: 10.2967/jnumed.118.216697) (PMID:30166353)

Almasaudi, A. S., McSorley, S. T. , Horgan, P. G. , McMillan, D. C. and Edwards, C. A. (2019) The relationship between body mass index, sex, and postoperative outcomes in patients undergoing potentially curative surgery for colorectal cancer. Clinical Nutrition ESPEN, 30, pp. 185-189. (doi: 10.1016/j.clnesp.2018.12.084) (PMID:30904219)

Roseweir, A. K. , Powell, A. G.M.T., Horstman, S. L., Inthagard, J., Park, J. A. , McMillan, D. C. , Horgan, P. G. and Edwards, J. (2019) Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer. Cellular Signalling, 56, pp. 15-22. (doi: 10.1016/j.cellsig.2019.01.007) (PMID:30684564)

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Bennett, L., Mallon, E. A., Horgan, P. G. , Paul, A., McMillan, D. C. and Edwards, J. (2017) The relationship between members of the canonical NF-KB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer. Oncotarget, 8(20), pp. 33002-33013. (doi: 10.18632/oncotarget.16031) (PMID:28423692)

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Bennett, L., Quinn, J. , McCall, P., Mallon, E. A., Horgan, P. G. , McMillan, D. C. , Paul, A. and Edwards, J. (2017) High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer. International Journal of Cancer, 140(7), pp. 1633-1644. (doi: 10.1002/ijc.30578) (PMID:28006839)

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