Ms Louise Mccombie
- Affiliate (School of Medicine, Dentistry & Nursing)
email:
Louise.Mccombie@glasgow.ac.uk
School of Medicine, Dentistry & Nursing, Royal Infirmary Site
Publications
2024
Pugh, J. E. et al. (2024) Increase in colonic PRopionate as a method of prEVENTing weight gain over 12 months in adults aged 20–40 years (iPREVENT): a multi-centre, double-blind, randomised, parallel-group trial. EClinicalMedicine, 76, 102844. (doi: 10.1016/j.eclinm.2024.102844) (PMID:39391015) (PMCID:PMC11466568)
Lean, M. E.J. et al. (2024) 5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study. Lancet Diabetes and Endocrinology, 12(4), pp. 233-246. (doi: 10.1016/S2213-8587(23)00385-6) (PMID:38423026)
2023
Sharma, V., Ricketts, H. C., McCombie, L., Brosnahan, N. , Crawford, L., Slaughter, L., Goodfellow, A., Lean, M. E.J. and Cowan, D. C. (2023) A total diet replacement weight management programme for difficult-to-treat asthma associated with obesity: a randomised controlled feasibility trial. Chest, 163(5), pp. 1026-1037. (doi: 10.1016/j.chest.2023.01.015) (PMID:36649753)
Cassidy, S. et al. (2023) Physical activity, inactivity and sleep during the Diabetes Remission Clinical Trial (DiRECT). Diabetic Medicine, 40(3), e15010. (doi: 10.1111/dme.15010) (PMID:36398460)
Sattar, N. , Welsh, P. , Leslie, W. S., Thom, G. , McCombie, L., Brosnahan, N. , Richardson, J. , Gill, J. M. R. , Crawford, L. and Lean, M. E. J. (2023) Dietary weight-management for type 2 diabetes remissions in South Asians: the South Asian diabetes remission randomised trial for proof-of-concept and feasibility (STANDby). Lancet Regional Health – Southeast Asia, 9, 100111. (doi: 10.1016/j.lansea.2022.100111) (PMID:36777452) (PMCID:PMC9904218)
2022
Pugh, J. E. et al. (2022) Increase in colonic PRopionate as a method of prEVENTing weight gain in adults aged 20–40 years (iPREVENT): a multi-centre, double-blind, randomised, parallel-group study to investigate the efficacy of inulin-propionate ester versus inulin (control) in the prevention of weight gain over 12 months. F1000Research, (doi: 10.12688/f1000research.125950.1)
Lean, M. , McCombie, L. and Xin, Y. (2022) Forget polypharmacy for type 2 diabetes! Weight management is a better investment. Nephrology Dialysis Transplantation, 37(5), pp. 844-846. (doi: 10.1093/ndt/gfaa250) (PMID:33263751)
Rehackova, L., Taylor, R., Lean, M. , Barnes, A., McCombie, L., Thom, G. , Brosnahan, N. , Leslie, W. S. and Sniehotta, F. F. (2022) Delivering the Diabetes Remission Clinical Trial (DiRECT) in primary care: experiences of healthcare professionals. Diabetic Medicine, 39(3), e14752. (doi: 10.1111/dme.14752) (PMID:34837259)
Rehackova, L. et al. (2022) Participant experiences in the Diabetes REmission Clinical Trial (DiRECT). Diabetic Medicine, 39(1), e14689. (doi: 10.1111/dme.14689) (PMID:34519099)
2021
Leslie, W. S. et al. (2021) Antihypertensive medication needs and blood pressure control with weight loss in the Diabetes Remission Clinical Trial (DiRECT). Diabetologia, 64(9), pp. 1927-1938. (doi: 10.1007/s00125-021-05471-x) (PMID:34056684)
Thom, G. et al. (2021) Predictors of type 2 diabetes in the Diabetes Remission Clinical Trial (DiRECT). Diabetic Medicine, 38(8), e14395. (doi: 10.1111/dme.14395) (PMID:32870520)
Brosnahan, N. , Leslie, W., McCombie, L., Barnes, A., Thom, G. , McConnachie, A. , Messow, C. M. , Sattar, N. , Taylor, R. and Lean, M. E.J. (2021) Brief formula low‐energy‐diet for relapse management during weight loss maintenance in the Diabetes Remission Clinical Trial (DiRECT). Journal of Human Nutrition and Dietetics, 34(3), pp. 472-479. (doi: 10.1111/jhn.12839) (PMID:33406285)
Thom, G. et al. (2021) Weight loss induced increase in fasting ghrelin concentration is a predictor of weight regain: evidence from the Diabetes Remission Clinical Trial. Diabetes, Obesity and Metabolism, 23(3), pp. 711-719. (doi: 10.1111/dom.14274) (PMID:33369058)
2020
Xin, Y. , Davies, A., Briggs, A. , McCombie, L., Messow, C. M. , Grieve, E. , Leslie, W. S., Taylor, R. and Lean, M. E.J. (2020) Type 2 diabetes remission: 2 year within-trial and lifetime-horizon cost-effectiveness of the Diabetes Remission Clinical Trial (DiRECT)/Counterweight-Plus weight management programme. Diabetologia, 63, pp. 2112-2122. (doi: 10.1007/s00125-020-05224-2) (PMID:32776237) (PMCID:PMC7476973)
2019
Lean, M. , McCombie, L. and McSorely, J. (2019) Trends in type 2 diabetes. British Medical Journal, 366, l5407. (doi: 10.1136/bmj.l5407) (PMID:31511237)
McCombie, L., Brosnahan, N. , Ross, H., Bell-Higgs, A., Govan, L. and Lean, M.E.J. (2019) Filling the intervention gap: service evaluation of an intensive nonsurgical weight management programme for severe and complex obesity. Journal of Human Nutrition and Dietetics, 32(3), pp. 329-337. (doi: 10.1111/jhn.12611) (PMID:30565772)
Xin, Y. , Davies, A., McCombie, L., Briggs, A. , Messow, C.-M. , Grieve, E. , Leslie, W. S., Taylor, R. and Lean, M. E.J. (2019) Within-trial cost and 1-year cost-effectiveness of the DiRECT/Counterweight-Plus weight-management programme to achieve remission of type 2 diabetes. Lancet Diabetes and Endocrinology, 7(3), pp. 169-172. (doi: 10.1016/S2213-8587(18)30346-2) (PMID:30581081)
Angelopoulou, K., Leslie, W., McCombie, L., Lean, M. and Hankey, C. (2019) Diabetes and travel insurance costs: let's talk about remission. Practical Diabetes, 36(1), pp. 20-21. (doi: 10.1002/pdi.2205)
2018
McCombie, L. and Grieve, E. (2018) Economic cost of obesity and the cost‐effectiveness of weight management. In: Hankey, C. and Whelan, K. (eds.) Advanced Nutrition and Dietetics in Obesity. John Wiley & Sons, Ltd, pp. 252-259. ISBN 9780470670767 (doi: 10.1002/9781118857991.ch4)
2017
McCombie, L., Leslie, W., Taylor, R., Kennon, B., Sattar, N. and Lean, M. E.J. (2017) Beating type 2 diabetes into remission. British Medical Journal, 358, j4030. (doi: 10.1136/bmj.j4030) (PMID:28903916)
2015
McCombie, L., Lean, M. E.J. and Tigbe, W. W. (2015) Cost-effectiveness of obesity treatment. Medicine, 43(2), pp. 104-107. (doi: 10.1016/j.mpmed.2014.11.007)
Articles
Pugh, J. E. et al. (2024) Increase in colonic PRopionate as a method of prEVENTing weight gain over 12 months in adults aged 20–40 years (iPREVENT): a multi-centre, double-blind, randomised, parallel-group trial. EClinicalMedicine, 76, 102844. (doi: 10.1016/j.eclinm.2024.102844) (PMID:39391015) (PMCID:PMC11466568)
Lean, M. E.J. et al. (2024) 5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study. Lancet Diabetes and Endocrinology, 12(4), pp. 233-246. (doi: 10.1016/S2213-8587(23)00385-6) (PMID:38423026)
Sharma, V., Ricketts, H. C., McCombie, L., Brosnahan, N. , Crawford, L., Slaughter, L., Goodfellow, A., Lean, M. E.J. and Cowan, D. C. (2023) A total diet replacement weight management programme for difficult-to-treat asthma associated with obesity: a randomised controlled feasibility trial. Chest, 163(5), pp. 1026-1037. (doi: 10.1016/j.chest.2023.01.015) (PMID:36649753)
Cassidy, S. et al. (2023) Physical activity, inactivity and sleep during the Diabetes Remission Clinical Trial (DiRECT). Diabetic Medicine, 40(3), e15010. (doi: 10.1111/dme.15010) (PMID:36398460)
Sattar, N. , Welsh, P. , Leslie, W. S., Thom, G. , McCombie, L., Brosnahan, N. , Richardson, J. , Gill, J. M. R. , Crawford, L. and Lean, M. E. J. (2023) Dietary weight-management for type 2 diabetes remissions in South Asians: the South Asian diabetes remission randomised trial for proof-of-concept and feasibility (STANDby). Lancet Regional Health – Southeast Asia, 9, 100111. (doi: 10.1016/j.lansea.2022.100111) (PMID:36777452) (PMCID:PMC9904218)
Pugh, J. E. et al. (2022) Increase in colonic PRopionate as a method of prEVENTing weight gain in adults aged 20–40 years (iPREVENT): a multi-centre, double-blind, randomised, parallel-group study to investigate the efficacy of inulin-propionate ester versus inulin (control) in the prevention of weight gain over 12 months. F1000Research, (doi: 10.12688/f1000research.125950.1)
Lean, M. , McCombie, L. and Xin, Y. (2022) Forget polypharmacy for type 2 diabetes! Weight management is a better investment. Nephrology Dialysis Transplantation, 37(5), pp. 844-846. (doi: 10.1093/ndt/gfaa250) (PMID:33263751)
Rehackova, L., Taylor, R., Lean, M. , Barnes, A., McCombie, L., Thom, G. , Brosnahan, N. , Leslie, W. S. and Sniehotta, F. F. (2022) Delivering the Diabetes Remission Clinical Trial (DiRECT) in primary care: experiences of healthcare professionals. Diabetic Medicine, 39(3), e14752. (doi: 10.1111/dme.14752) (PMID:34837259)
Rehackova, L. et al. (2022) Participant experiences in the Diabetes REmission Clinical Trial (DiRECT). Diabetic Medicine, 39(1), e14689. (doi: 10.1111/dme.14689) (PMID:34519099)
Leslie, W. S. et al. (2021) Antihypertensive medication needs and blood pressure control with weight loss in the Diabetes Remission Clinical Trial (DiRECT). Diabetologia, 64(9), pp. 1927-1938. (doi: 10.1007/s00125-021-05471-x) (PMID:34056684)
Thom, G. et al. (2021) Predictors of type 2 diabetes in the Diabetes Remission Clinical Trial (DiRECT). Diabetic Medicine, 38(8), e14395. (doi: 10.1111/dme.14395) (PMID:32870520)
Brosnahan, N. , Leslie, W., McCombie, L., Barnes, A., Thom, G. , McConnachie, A. , Messow, C. M. , Sattar, N. , Taylor, R. and Lean, M. E.J. (2021) Brief formula low‐energy‐diet for relapse management during weight loss maintenance in the Diabetes Remission Clinical Trial (DiRECT). Journal of Human Nutrition and Dietetics, 34(3), pp. 472-479. (doi: 10.1111/jhn.12839) (PMID:33406285)
Thom, G. et al. (2021) Weight loss induced increase in fasting ghrelin concentration is a predictor of weight regain: evidence from the Diabetes Remission Clinical Trial. Diabetes, Obesity and Metabolism, 23(3), pp. 711-719. (doi: 10.1111/dom.14274) (PMID:33369058)
Xin, Y. , Davies, A., Briggs, A. , McCombie, L., Messow, C. M. , Grieve, E. , Leslie, W. S., Taylor, R. and Lean, M. E.J. (2020) Type 2 diabetes remission: 2 year within-trial and lifetime-horizon cost-effectiveness of the Diabetes Remission Clinical Trial (DiRECT)/Counterweight-Plus weight management programme. Diabetologia, 63, pp. 2112-2122. (doi: 10.1007/s00125-020-05224-2) (PMID:32776237) (PMCID:PMC7476973)
Lean, M. , McCombie, L. and McSorely, J. (2019) Trends in type 2 diabetes. British Medical Journal, 366, l5407. (doi: 10.1136/bmj.l5407) (PMID:31511237)
McCombie, L., Brosnahan, N. , Ross, H., Bell-Higgs, A., Govan, L. and Lean, M.E.J. (2019) Filling the intervention gap: service evaluation of an intensive nonsurgical weight management programme for severe and complex obesity. Journal of Human Nutrition and Dietetics, 32(3), pp. 329-337. (doi: 10.1111/jhn.12611) (PMID:30565772)
Xin, Y. , Davies, A., McCombie, L., Briggs, A. , Messow, C.-M. , Grieve, E. , Leslie, W. S., Taylor, R. and Lean, M. E.J. (2019) Within-trial cost and 1-year cost-effectiveness of the DiRECT/Counterweight-Plus weight-management programme to achieve remission of type 2 diabetes. Lancet Diabetes and Endocrinology, 7(3), pp. 169-172. (doi: 10.1016/S2213-8587(18)30346-2) (PMID:30581081)
Angelopoulou, K., Leslie, W., McCombie, L., Lean, M. and Hankey, C. (2019) Diabetes and travel insurance costs: let's talk about remission. Practical Diabetes, 36(1), pp. 20-21. (doi: 10.1002/pdi.2205)
McCombie, L., Leslie, W., Taylor, R., Kennon, B., Sattar, N. and Lean, M. E.J. (2017) Beating type 2 diabetes into remission. British Medical Journal, 358, j4030. (doi: 10.1136/bmj.j4030) (PMID:28903916)
McCombie, L., Lean, M. E.J. and Tigbe, W. W. (2015) Cost-effectiveness of obesity treatment. Medicine, 43(2), pp. 104-107. (doi: 10.1016/j.mpmed.2014.11.007)
Book Sections
McCombie, L. and Grieve, E. (2018) Economic cost of obesity and the cost‐effectiveness of weight management. In: Hankey, C. and Whelan, K. (eds.) Advanced Nutrition and Dietetics in Obesity. John Wiley & Sons, Ltd, pp. 252-259. ISBN 9780470670767 (doi: 10.1002/9781118857991.ch4)