Dr Iain Rowe
- Affiliate (School of Medicine, Dentistry & Nursing)
email:
Iain.Rowe@glasgow.ac.uk
School of Life Sciences, College of Medical, Veterinary and Life Sciences, Sir James Black Building, University of Glasgow
https://orcid.org/0000-0002-0148-5332Publications
2021
Logan, G. , Bowers, M. , Davidson, P., Price, K. and Rowe, I. (2021) Life Science Mini Projects: Taking the Lab Outside the Laboratory. Enhancing Student Learning Through Innovative Scholarship Conference, 10 Sep 2021.
Baxendale, R., Bowers, M. , Davidson, P., Logan, G. , Price, K. and Rowe, I. (2021) Academics, Technicians and Students: Co-Creating a Remote Mini-Project in Life Sciences. 14th Annual University of Glasgow Learning and Teaching Conference, 18 Jun 2021. (Unpublished)
2018
Tully, V., Al-Salti, S., Arnold, A., Botros, S., Campbell, I., Fane, R., Rowe, I. , Strath, A. and Davey, P. (2018) Interprofessional, student-led intervention to improve insulin prescribing to patients in an Acute Surgical Receiving Unit. BMJ Open Quality, 7(2), e000305. (doi: 10.1136/bmjoq-2017-000305) (PMID:30019012) (PMCID:PMC6045703)
2017
Steven, K., Howden, S., Mires, G., Rowe, I. , Lafferty, N., Arnold, A. and Strath, A. (2017) Toward interprofessional learning and education: mapping common outcomes for prequalifying healthcare professional programs in the United Kingdom. Medical Teacher, 39(7), pp. 720-744. (doi: 10.1080/0142159x.2017.1309372) (PMID:28462598)
2015
Filion-Murphy, C., Hands, L., Hockham, L., Kirkpatrick, L., McNamara, S., Strath, A., Rowe, I. and Vosper, H. (2015) Student-led development and evaluation of a community pharmacy-based cardiovascular risk assessment. Journal of Educational Innovation, Partnership and Change, 1(2), (doi: 10.21100/jeipc.v1i2.176)
2012
Dospinescu, C., Widmer, H., Rowe, I. , Wainwright, C. and Cruickshank, S. F. (2012) Hypoxia sensitivity of a voltage-gated potassium current in porcine intrapulmonary vein smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 303(5), L476-L486. (doi: 10.1152/ajplung.00157.2012) (PMID:22773694)
Rowe, I. , Rowan, E., Duncan, R. and Shipston, M. (2012) Investigating the effect of redox agents on structural re-arrangement of the BK channel RCK1-RCK2 linker using fluorescence lifetime imaging microscopy. Biophysical Journal, 102(3 S1), 689a-690a. (doi: 10.1016/j.bpj.2011.11.3745)
2011
Ross, F. A. et al. (2011) Selective expression in carotid body type I cells of a single splice variant of the large conductance calcium- and voltage-activated potassium channel confers regulation by AMP-activated protein kinase. Journal of Biological Chemistry, 286(14), pp. 11929-11936. (doi: 10.1074/jbc.M110.189779) (PMID:21209098) (PMCID:PMC3069395)
Rowe, I. , Saleem, F., Jeffries, O., McClafferty, H., McCartney, C., Rowan, E., Duncan, R. and Shipston, M. (2011) Investigating structural re-arrangement of the BK channel Rck1-Rck2 linker using fluorescence lifetime imaging microscopy. Biophysical Journal, 100(3), 260a. (doi: 10.1016/j.bpj.2010.12.1634)
2010
Jeffries, O., Geiger, N., Rowe, I. C. M. , Tian, L., McClafferty, H., Chen, L., Bi, D., Knaus, H. G., Ruth, P. and Shipston, M. J. (2010) Palmitoylation of the S0-S1 linker regulates cell surface expression of voltage- and calcium-activated potassium (BK) channels. Journal of Biological Chemistry, 285(43), pp. 33307-33314. (doi: 10.1074/jbc.M110.153940) (PMID:20693285) (PMCID:PMC2963414)
Chen, L., Jeffries, O., Rowe, I. C. M. , Liang, Z., Knaus, H.-G., Ruth, P. and Shipston, M. J. (2010) Membrane trafficking of large conductance calcium-activated potassium channels is regulated by alternative splicing of a transplantable, acidic trafficking motif in the RCK1-RCK2 linker. Journal of Biological Chemistry, 285(30), pp. 23265-23275. (doi: 10.1074/jbc.M110.139758) (PMID:20479001) (PMCID:PMC2906319)
2009
Tian, L., Jeffries, O., McClafferty, H., Molyvdas, A., Rowe, I. , Saleem, F., Chen, L. and Shipston, M. J. (2009) Palmitoylation controls BK channel regulation by phosphorylation. Biophysical Journal, 96(3), 473a. (doi: 10.1016/j.bpj.2008.12.2447)
Saleem, F., Rowe, I.C.M. and Shipston, M.J. (2009) Characterization of BK channel splice variants using membrane potential dyes. British Journal of Pharmacology, 156(1), pp. 143-152. (doi: 10.1111/j.1476-5381.2008.00011.x) (PMID:19068078) (PMCID:PMC2697775)
2008
Tian, L. et al. (2008) Palmitoylation gates phosphorylation-dependent regulation of BK potassium channels. Proceedings of the National Academy of Sciences of the United States of America, 105(52), pp. 21006-21011. (doi: 10.1073/pnas.0806700106) (PMID:19098106) (PMCID:PMC2605631)
2007
Sabatier, N., Rowe, I. and Leng, G. (2007) Central release of oxytocin and the ventromedial hypothalamus. Biochemical Society Transactions, 35(5), pp. 1247-1251. (doi: 10.1042/BST0351247) (PMID:17956323)
Vernon-Wilson, E. F.,, Auradé, F., Tian, L., Rowe, I. C.M. , Shipston, M. J., Savill, J. and Brown, S. B. (2007) CD31 delays phagocyte membrane repolarization to promote efficient binding of apoptotic cells. Journal of Leukocyte Biology, 82(5), pp. 1278-1288. (doi: 10.1189/jlb.0507283) (PMID:17684043)
2005
McCartney, C. E., McClafferty, H., Huibant, J.-M., Rowan, E. G., Shipston, M. J. and Rowe, I. C.M. (2005) A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage- and Ca-activated K (BK) channel α-subunits. Proceedings of the National Academy of Sciences of the United States of America, 102(49), pp. 17870-17875. (doi: 10.1073/pnas.0505270102) (PMID:16306267) (PMCID:PMC1308893)
2003
Widmer, H. A., Rowe, I. C. M. and Shipston, M. J. (2003) Conditional protein phosphorylation regulates BK channel activity in rat cerebellar Purkinje neurons. Journal of Physiology, 552(2), pp. 379-391. (doi: 10.1111/j.1469-7793.2003.00379.x)
1997
Lee, K., McKenna, F., Rowe, I.C.M. and Ashford, M.L.J. (1997) The effects of neuroleptic and tricyclic compounds on BK(Ca) channel activity in rat isolated cortical neurones. British Journal of Pharmacology, 121(8), pp. 1810-1816. (doi: 10.1038/sj.bjp.0701333) (PMID:9283722) (PMCID:PMC1564885)
Rowe, I.C.M. , Lee, K., Khan, R.N. and Ashford, M.L.J. (1997) Effect of englitazone on K(ATP) and calcium-activated nonselective cation channels in CRI-G1 insulin-secreting cells. British Journal of Pharmacology, 121(3), pp. 531-539. (doi: 10.1038/sj.bjp.0701145) (PMID:9179397) (PMCID:PMC1564701)
1996
Rowe, I.C. , Boden, P.R. and Ashford, M.L.J. (1996) Potassium channel dysfunction in hypothalamic glucose-receptive neurones of obese Zucker rats. Journal of Physiology, 497(2), pp. 365-377. (doi: 10.1113/jphysiol.1996.sp021774) (PMID:8961181)
Lee, K., Dixon, A. K., Rowe, I. C.M. , Ashford, M. L. J. and Richardson, P. J. (1996) The high-affinity sulphonylurea receptor regulates KATP channels in nerve terminals of the rat motor cortex. Journal of Neurochemistry, 66(6), pp. 2562-2571. (doi: 10.1046/j.1471-4159.1996.66062562.x) (PMID:8632183)
Lee, K., Khan, R.N., Rowe, I.C. , Ozanne, S.E., Hall, A.C., Papadakis, E., Hales, C.N. and Ashford, M.L.J. (1996) Ciclazindol inhibits ATP-sensitive K+ channels and stimulates insulin secretion in CRI-G1 insulin-secreting cells. Molecular Pharmacology, 49(4), pp. 715-720. (PMID:8609901)
Rowe, I.C.M. , Treherne, J.M. and Ashford, M.L.J. (1996) Activation by intracellular ATP of a potassium channel in neurones from rat basomedial hypothalamus. Journal of Physiology, 490(1), pp. 97-113. (doi: 10.1113/jphysiol.1996.sp021129) (PMID:8745281)
1995
Lee, K., Rowe, I.C.M. and Ashford, M.L.J. (1995) Characterization of an ATP-modulated large conductance Ca2+-activated K+ channel present in rat cortical neurones. Journal of Physiology, 488(2), pp. 319-337. (doi: 10.1113/jphysiol.1995.sp020969) (PMID:8568673)
Lee, K., Rowe, I. C.M. and Ashford, M. L. J. (1995) NS 1619 activates BKCa channel activity in rat cortical neurones. European Journal of Pharmacology, 280(2), pp. 215-219. (doi: 10.1016/0014-2999(95)00251-F) (PMID:7589189)
Bond, C.T. et al. (1995) Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic β-cells and in the brain. FEBS Letters, 367(1), pp. 61-66. (doi: 10.1016/0014-5793(95)00497-W) (PMID:7601286)
Lee, K., Dixon, A. K., Rowe, I. C.M. , Ashford, M. L. J. and Richardson, P. J. (1995) Direct demonstration of sulphonylurea-sensitive KATP channels on nerve terminals of the rat motor cortex. British Journal of Pharmacology, 115(3), pp. 385-388. (doi: 10.1111/j.1476-5381.1995.tb16344.x) (PMID:7582446) (PMCID:PMC1908424)
1994
Lee, K., Ozanne, S.E., Rowe, I.C. , Hales, C.N. and Ashford, M.L.J. (1994) The effects of trypsin on ATP-sensitive potassium channel properties and sulfonylurea receptors in the CRI-G1 insulin-secreting cell line. Molecular Pharmacology, 46(1), pp. 176-185. (PMID:8058051)
1993
Rowe, I.C.M. and Ashford, M.L.J. (1993) The effects of adenosine and guanine nucleotides on the ATP-activated K+ channel in rat isolated hypothalamic neurones. Journal of Physiology, 467(suppl), p. 268. (doi: 10.1113/jphysiol.1993.sp019753)
1992
Rowe, I.C.M. and Ashford, M.L.J. (1992) The effects of Mg2+ ions on the inhibition of the ATP-sensitive K+ channel by adenosine nucleotides in rat isolated hypothalamic neurones. Journal of Physiology, 446(suppl), p. 274. (doi: 10.1113/jphysiol.1992.sp018976)
1990
Rowe, I.C.M. , Wareham, A.C. and Whittle, M.A. (1990) Potassium channel activity in sarcolemmal vesicles formed from skeletal muscle fibres of normal and dystrophic mice. Journal of the Neurological Sciences, 98(1), pp. 51-61. (doi: 10.1016/0022-510X(90)90181-L) (PMID:2230831)
Wareham, A.C., Rowe, I.C.M. and Whittle, M.A. (1990) Sarcolemmal K+ channel activity in developing rat skeletal muscle membranes. Journal of the Neurological Sciences, 96(2-3), pp. 321-331. (doi: 10.1016/0022-510X(90)90142-A) (PMID:2376760)
Articles
Tully, V., Al-Salti, S., Arnold, A., Botros, S., Campbell, I., Fane, R., Rowe, I. , Strath, A. and Davey, P. (2018) Interprofessional, student-led intervention to improve insulin prescribing to patients in an Acute Surgical Receiving Unit. BMJ Open Quality, 7(2), e000305. (doi: 10.1136/bmjoq-2017-000305) (PMID:30019012) (PMCID:PMC6045703)
Steven, K., Howden, S., Mires, G., Rowe, I. , Lafferty, N., Arnold, A. and Strath, A. (2017) Toward interprofessional learning and education: mapping common outcomes for prequalifying healthcare professional programs in the United Kingdom. Medical Teacher, 39(7), pp. 720-744. (doi: 10.1080/0142159x.2017.1309372) (PMID:28462598)
Filion-Murphy, C., Hands, L., Hockham, L., Kirkpatrick, L., McNamara, S., Strath, A., Rowe, I. and Vosper, H. (2015) Student-led development and evaluation of a community pharmacy-based cardiovascular risk assessment. Journal of Educational Innovation, Partnership and Change, 1(2), (doi: 10.21100/jeipc.v1i2.176)
Dospinescu, C., Widmer, H., Rowe, I. , Wainwright, C. and Cruickshank, S. F. (2012) Hypoxia sensitivity of a voltage-gated potassium current in porcine intrapulmonary vein smooth muscle cells. American Journal of Physiology: Lung Cellular and Molecular Physiology, 303(5), L476-L486. (doi: 10.1152/ajplung.00157.2012) (PMID:22773694)
Rowe, I. , Rowan, E., Duncan, R. and Shipston, M. (2012) Investigating the effect of redox agents on structural re-arrangement of the BK channel RCK1-RCK2 linker using fluorescence lifetime imaging microscopy. Biophysical Journal, 102(3 S1), 689a-690a. (doi: 10.1016/j.bpj.2011.11.3745)
Ross, F. A. et al. (2011) Selective expression in carotid body type I cells of a single splice variant of the large conductance calcium- and voltage-activated potassium channel confers regulation by AMP-activated protein kinase. Journal of Biological Chemistry, 286(14), pp. 11929-11936. (doi: 10.1074/jbc.M110.189779) (PMID:21209098) (PMCID:PMC3069395)
Rowe, I. , Saleem, F., Jeffries, O., McClafferty, H., McCartney, C., Rowan, E., Duncan, R. and Shipston, M. (2011) Investigating structural re-arrangement of the BK channel Rck1-Rck2 linker using fluorescence lifetime imaging microscopy. Biophysical Journal, 100(3), 260a. (doi: 10.1016/j.bpj.2010.12.1634)
Jeffries, O., Geiger, N., Rowe, I. C. M. , Tian, L., McClafferty, H., Chen, L., Bi, D., Knaus, H. G., Ruth, P. and Shipston, M. J. (2010) Palmitoylation of the S0-S1 linker regulates cell surface expression of voltage- and calcium-activated potassium (BK) channels. Journal of Biological Chemistry, 285(43), pp. 33307-33314. (doi: 10.1074/jbc.M110.153940) (PMID:20693285) (PMCID:PMC2963414)
Chen, L., Jeffries, O., Rowe, I. C. M. , Liang, Z., Knaus, H.-G., Ruth, P. and Shipston, M. J. (2010) Membrane trafficking of large conductance calcium-activated potassium channels is regulated by alternative splicing of a transplantable, acidic trafficking motif in the RCK1-RCK2 linker. Journal of Biological Chemistry, 285(30), pp. 23265-23275. (doi: 10.1074/jbc.M110.139758) (PMID:20479001) (PMCID:PMC2906319)
Tian, L., Jeffries, O., McClafferty, H., Molyvdas, A., Rowe, I. , Saleem, F., Chen, L. and Shipston, M. J. (2009) Palmitoylation controls BK channel regulation by phosphorylation. Biophysical Journal, 96(3), 473a. (doi: 10.1016/j.bpj.2008.12.2447)
Saleem, F., Rowe, I.C.M. and Shipston, M.J. (2009) Characterization of BK channel splice variants using membrane potential dyes. British Journal of Pharmacology, 156(1), pp. 143-152. (doi: 10.1111/j.1476-5381.2008.00011.x) (PMID:19068078) (PMCID:PMC2697775)
Tian, L. et al. (2008) Palmitoylation gates phosphorylation-dependent regulation of BK potassium channels. Proceedings of the National Academy of Sciences of the United States of America, 105(52), pp. 21006-21011. (doi: 10.1073/pnas.0806700106) (PMID:19098106) (PMCID:PMC2605631)
Sabatier, N., Rowe, I. and Leng, G. (2007) Central release of oxytocin and the ventromedial hypothalamus. Biochemical Society Transactions, 35(5), pp. 1247-1251. (doi: 10.1042/BST0351247) (PMID:17956323)
Vernon-Wilson, E. F.,, Auradé, F., Tian, L., Rowe, I. C.M. , Shipston, M. J., Savill, J. and Brown, S. B. (2007) CD31 delays phagocyte membrane repolarization to promote efficient binding of apoptotic cells. Journal of Leukocyte Biology, 82(5), pp. 1278-1288. (doi: 10.1189/jlb.0507283) (PMID:17684043)
McCartney, C. E., McClafferty, H., Huibant, J.-M., Rowan, E. G., Shipston, M. J. and Rowe, I. C.M. (2005) A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage- and Ca-activated K (BK) channel α-subunits. Proceedings of the National Academy of Sciences of the United States of America, 102(49), pp. 17870-17875. (doi: 10.1073/pnas.0505270102) (PMID:16306267) (PMCID:PMC1308893)
Widmer, H. A., Rowe, I. C. M. and Shipston, M. J. (2003) Conditional protein phosphorylation regulates BK channel activity in rat cerebellar Purkinje neurons. Journal of Physiology, 552(2), pp. 379-391. (doi: 10.1111/j.1469-7793.2003.00379.x)
Lee, K., McKenna, F., Rowe, I.C.M. and Ashford, M.L.J. (1997) The effects of neuroleptic and tricyclic compounds on BK(Ca) channel activity in rat isolated cortical neurones. British Journal of Pharmacology, 121(8), pp. 1810-1816. (doi: 10.1038/sj.bjp.0701333) (PMID:9283722) (PMCID:PMC1564885)
Rowe, I.C.M. , Lee, K., Khan, R.N. and Ashford, M.L.J. (1997) Effect of englitazone on K(ATP) and calcium-activated nonselective cation channels in CRI-G1 insulin-secreting cells. British Journal of Pharmacology, 121(3), pp. 531-539. (doi: 10.1038/sj.bjp.0701145) (PMID:9179397) (PMCID:PMC1564701)
Rowe, I.C. , Boden, P.R. and Ashford, M.L.J. (1996) Potassium channel dysfunction in hypothalamic glucose-receptive neurones of obese Zucker rats. Journal of Physiology, 497(2), pp. 365-377. (doi: 10.1113/jphysiol.1996.sp021774) (PMID:8961181)
Lee, K., Dixon, A. K., Rowe, I. C.M. , Ashford, M. L. J. and Richardson, P. J. (1996) The high-affinity sulphonylurea receptor regulates KATP channels in nerve terminals of the rat motor cortex. Journal of Neurochemistry, 66(6), pp. 2562-2571. (doi: 10.1046/j.1471-4159.1996.66062562.x) (PMID:8632183)
Lee, K., Khan, R.N., Rowe, I.C. , Ozanne, S.E., Hall, A.C., Papadakis, E., Hales, C.N. and Ashford, M.L.J. (1996) Ciclazindol inhibits ATP-sensitive K+ channels and stimulates insulin secretion in CRI-G1 insulin-secreting cells. Molecular Pharmacology, 49(4), pp. 715-720. (PMID:8609901)
Rowe, I.C.M. , Treherne, J.M. and Ashford, M.L.J. (1996) Activation by intracellular ATP of a potassium channel in neurones from rat basomedial hypothalamus. Journal of Physiology, 490(1), pp. 97-113. (doi: 10.1113/jphysiol.1996.sp021129) (PMID:8745281)
Lee, K., Rowe, I.C.M. and Ashford, M.L.J. (1995) Characterization of an ATP-modulated large conductance Ca2+-activated K+ channel present in rat cortical neurones. Journal of Physiology, 488(2), pp. 319-337. (doi: 10.1113/jphysiol.1995.sp020969) (PMID:8568673)
Lee, K., Rowe, I. C.M. and Ashford, M. L. J. (1995) NS 1619 activates BKCa channel activity in rat cortical neurones. European Journal of Pharmacology, 280(2), pp. 215-219. (doi: 10.1016/0014-2999(95)00251-F) (PMID:7589189)
Bond, C.T. et al. (1995) Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic β-cells and in the brain. FEBS Letters, 367(1), pp. 61-66. (doi: 10.1016/0014-5793(95)00497-W) (PMID:7601286)
Lee, K., Dixon, A. K., Rowe, I. C.M. , Ashford, M. L. J. and Richardson, P. J. (1995) Direct demonstration of sulphonylurea-sensitive KATP channels on nerve terminals of the rat motor cortex. British Journal of Pharmacology, 115(3), pp. 385-388. (doi: 10.1111/j.1476-5381.1995.tb16344.x) (PMID:7582446) (PMCID:PMC1908424)
Lee, K., Ozanne, S.E., Rowe, I.C. , Hales, C.N. and Ashford, M.L.J. (1994) The effects of trypsin on ATP-sensitive potassium channel properties and sulfonylurea receptors in the CRI-G1 insulin-secreting cell line. Molecular Pharmacology, 46(1), pp. 176-185. (PMID:8058051)
Rowe, I.C.M. and Ashford, M.L.J. (1993) The effects of adenosine and guanine nucleotides on the ATP-activated K+ channel in rat isolated hypothalamic neurones. Journal of Physiology, 467(suppl), p. 268. (doi: 10.1113/jphysiol.1993.sp019753)
Rowe, I.C.M. and Ashford, M.L.J. (1992) The effects of Mg2+ ions on the inhibition of the ATP-sensitive K+ channel by adenosine nucleotides in rat isolated hypothalamic neurones. Journal of Physiology, 446(suppl), p. 274. (doi: 10.1113/jphysiol.1992.sp018976)
Rowe, I.C.M. , Wareham, A.C. and Whittle, M.A. (1990) Potassium channel activity in sarcolemmal vesicles formed from skeletal muscle fibres of normal and dystrophic mice. Journal of the Neurological Sciences, 98(1), pp. 51-61. (doi: 10.1016/0022-510X(90)90181-L) (PMID:2230831)
Wareham, A.C., Rowe, I.C.M. and Whittle, M.A. (1990) Sarcolemmal K+ channel activity in developing rat skeletal muscle membranes. Journal of the Neurological Sciences, 96(2-3), pp. 321-331. (doi: 10.1016/0022-510X(90)90142-A) (PMID:2376760)
Conference or Workshop Item
Logan, G. , Bowers, M. , Davidson, P., Price, K. and Rowe, I. (2021) Life Science Mini Projects: Taking the Lab Outside the Laboratory. Enhancing Student Learning Through Innovative Scholarship Conference, 10 Sep 2021.
Baxendale, R., Bowers, M. , Davidson, P., Logan, G. , Price, K. and Rowe, I. (2021) Academics, Technicians and Students: Co-Creating a Remote Mini-Project in Life Sciences. 14th Annual University of Glasgow Learning and Teaching Conference, 18 Jun 2021. (Unpublished)