2024

Bradley, N. A., Walter, A., Wilson, A., Siddiqui, T., Roxburgh, C. S.D. , Guthrie, G. J.K. and McMillan, D. C. (2024) The relationship between peri-operative systemic inflammation and survival in patients with abdominal aortic aneurysm. Annals of Vascular Surgery, (doi: 10.1016/j.avsg.2024.08.024) (PMID:39395590) (In Press)

Galbraith, N. J. et al. (2024) TAK1 expression is associated with increased PD-L1 and decreased cancer-specific survival in microsatellite-stable colorectal cancer. Translational Oncology, 48, 102064. (doi: 10.1016/j.tranon.2024.102064) (PMID:39068768)

Pumtako, C. , Dolan, R. D. , McGovern, J. and McMillan, D. C. (2024) Routine assessment of nutritional, functional and inflammatory criteria in patients with cancer: a systematic review. Clinical Nutrition ESPEN, 63, pp. 294-303. (doi: 10.1016/j.clnesp.2024.06.052) (PMID:38980797)

Shamis, S. A.K. et al. (2024) Elucidation of dysregulated pathways associated with hypoxia in ER-negative breast cancer. Cancer Medicine, (Accepted for Publication)

McGovern, J., Skipworth, R. J.E., Laird, B. J.A. and McMillan, D. C. (2024) Global Leadership Initiative on Malnutrition cachexia: an inflammation-first approach for the diagnosis of disease-related malnutrition. Current Opinion in Clinical Nutrition and Metabolic Care, 27(5), pp. 393-396. (doi: 10.1097/mco.0000000000001052) (PMID:39110108)

Bradley, N. A., Roxburgh, C. S.D. , McMillan, D. C. and Guthrie, G. J.K. (2024) A systematic review of the role of systemic inflammation-based prognostic scores in patients with abdominal aortic aneurysm. Surgeon, (doi: 10.1016/j.surge.2024.08.014) (Early Online Publication)

Abbass, T. , Dolan, R. D. , Horgan, P. G., MacLeod, N., Skipworth, R. J., Laird, B. J. and McMillan, D. C. (2024) CT derived measurement of body composition: Observations from a comparative analysis of patients with colorectal and lung cancer. Nutrition and Cancer, (doi: 10.1080/01635581.2024.2392913) (PMID:39180189) (Early Online Publication)

McGovern, J. et al. (2024) The prevalence and prognostic value of systemic inflammation in good performance status patients with advanced, inoperable non-small cell lung cancer receiving palliative radiotherapy: comparison of composite ratios and cumulative scores. Cancer Medicine, 13(16), e70139. (doi: 10.1002/cam4.70139) (PMCID:PMC11335809)

Golder, A. M. , Ferguson, M., McMillan, P., Mansouri, D. , Horgan, P. G. , Roxburgh, C. S. , Dolan, R. D. , McGovern, J. and McMillan, D. (2024) CT-derived body composition and differential association with age, TNM stage and systemic inflammation in patients with colon cancer. Scientific Reports, 14, 15673. (doi: 10.1038/s41598-024-65871-y) (PMID:38977870) (PMCID:PMC11231341)

Knight, K., Bigley, C., Pennel, K. , Hay, J., Maka, N., McMillan, D. , Park, J. , Roxburgh, C. and Edwards, J. (2024) The Glasgow Microenvironment Score: an exemplar of contemporary biomarker evolution in colorectal cancer. Journal of Pathology: Clinical Research, 10, e12385. (doi: 10.1002/2056-4538.12385) (PMID:38853386)

Bradley, N.A., Walter, A., Roxburgh, C.S.D. , McMillan, D.C. and Guthrie, G.J.K. (2024) The relationship between clinical frailty score, CT-derived body composition, systemic inflammation, and survival in patients with chronic limb threatening ischaemia. Annals of Vascular Surgery, 104, pp. 18-26. (doi: 10.1016/j.avsg.2023.06.012) (PMID:37356659)

Bradley, N. A., Walter, A., Roxburgh, C. S.D. , McMillan, D. C. and Guthrie, G. J.K. (2024) The relationship between Clinical Frailty Score, CT-derived body composition, systemic inflammation, and survival in patients with chronic limb-threatening ischemia. Annals of Vascular Surgery, 104, pp. 18-26. (doi: 10.1016/j.avsg.2023.06.012) (PMID:37356659)

Thompson, J., McGovern, J., Roxburgh, C. , Edwards, J. , Dolan, R. D. and McMillan, D. C. (2024) The relationship between LDH and GLIM criteria for cancer cachexia: systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 199, 104378. (doi: 10.1016/j.critrevonc.2024.104378) (PMID:38754770)

McGovern, J. and McMillan, D. C. (2024) Comment on “A promising prognostic grading system incorporating weight loss and inflammation in patients with advanced cancer” by Zhang et al. Journal of Cachexia, Sarcopenia and Muscle, 15(3), pp. 1218-1219. (doi: 10.1002/jcsm.13452) (PMID:38468144) (PMCID:PMC11154785)

Bradley, N. A., Roxburgh, C. S.D. , McMillan, D. C. and Guthrie, G. J.K. (2024) A systematic review of the neutrophil to lymphocyte and platelet to lymphocyte ratios in patients with lower extremity arterial disease. European Journal of Vascular Medicine, 53(3), pp. 155-171. (doi: 10.1024/0301-1526/a001117) (PMID:38563057)

Hatthakarnkul, P. et al. (2024) Histopathological tumour microenvironment score independently predicts outcome in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 10(3), e12374. (doi: 10.1002/2056-4538.12374) (PMID:38650367) (PMCID:PMC11035902)

Brown, L. R. et al. (2024) Cachexia index for prognostication in surgical patients with locally advanced oesophageal or gastric cancer: multicentre cohort study. British Journal of Surgery, 111(4), znae098. (doi: 10.1093/bjs/znae098) (PMID:38593042) (PMCID:PMC11003541)

Bradley, N., Dosanj, K., Ming Chan, S. Y., Wilson, A., Siddiqui, T., Forsythe, R., Roxburgh, C. S.D. , McMillan, D. C. and Guthrie, G. J.K. (2024) The Relationship Between CT-derived Cervical Muscle Mass and Quality, Systemic Inflammation, and Survival in Symptomatic Patients Undergoing Carotid Endarterectomy. 2023 VEITHsymposium Associate Faculty Global Podium Presentations Program, New York, USA, 14-18 Nov 2023. 27S. (doi: 10.1016/j.jvs.2024.01.080)

Bradley, N. A., McGovern, J., Dolan, R. D. , Golder, A. M. , Roxburgh, C. S.D. , Guthrie, G. J.K. and McMillan, D. C. (2024) CT-derived body composition: Differential association with disease, age and inflammation in a retrospective cohort study. PLoS ONE, 19(3), e0300038. (doi: 10.1371/journal.pone.0300038) (PMID:38512880) (PMCID:PMC10956827)

Ingham,, A. R. et al. (2024) Robotic-assisted surgery for left sided colon and rectal resections is associated with reduction in the postoperative surgical stress response and improved short-term outcomes: a cohort study. Surgical Endoscopy, (doi: 10.1007/s00464-024-10749-3) (PMID:38498212)

Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4)

McGovern, J., Mackay, C., Freireich, R., Golder, A. M. , Dolan, R. D. , Horgan, P. G. , Holroyd, D., Jamieson, N. B. and McMillan, D. C. (2024) The relationship between liver volume, clinicopathological characteristics and survival in patients undergoing resection with curative intent for non-metastatic colonic cancer. Tomography, 10(3), pp. 349-359. (doi: 10.3390/tomography10030027) (PMID:38535769) (PMCID:PMC10974240)

Johnstone, M. S., McSorley, S. T. , McMillan, D. C. , Horgan, P. G. and Mansouri, D. (2024) The relationship between systemic inflammatory response, screen detection and outcome in colorectal cancer. Colorectal Disease, 26(1), pp. 81-94. (doi: 10.1111/codi.16824) (PMID:38095280)

Shamis, S. A. K., Savioli, F., Ammar, A. , Al-Badran, S. S.F., Hatthakarnkul, P., Leslie, H. , Mallon, E., Jamieson, N. B. , McMillan, D. C. and Edwards, J. (2024) Spatial transcriptomic analysis of tumour with high and low CAIX expression in TNBC tissue samples using GeoMx™ RNA assay. Histology and Histopathology: Cellular and Molecular Biology, 39, pp. 177-200. (doi: 10.14670/HH-18-655) (PMID:37681672)

2023

Saeed, R., McGovern, J., Bench, H., Dolan, R. D. , McMillan, D. C. and Cascales, A. (2023) The relationship between clinicopathological variables, systemic inflammation, and CT-derived body composition with survival in patients with advanced non-small cell lung cancer receiving nivolumab as a second-line treatment. Cancer Medicine, 12(24), pp. 22062-22070. (doi: 10.1002/cam4.6805) (PMID:38088761) (PMCID:PMC10757089)

Bradley, N.A., Walter, A., Wilson, A., Siddiqui, T., Roxburgh, C.S.D. , McMillan, D.C. and Guthrie, G.J.K. (2023) The relationship between CT-derived body composition, systemic inflammation, and survival in patients with abdominal aortic aneurysm. Journal of Vascular Surgery, 78(4), 937-944.e4. (doi: 10.1016/j.jvs.2023.06.012) (PMID:37385355)

Maguire, D. and McMillan, D. (2023) Magnesium in the treatment of alcohol withdrawal syndrome: a multicenter randomized controlled trial. Alcohol and Alcoholism, 58(5), p. 570. (doi: 10.1093/alcalc/agad040) (PMID:37311572) (PMCID:PMC10493515)

Bradley, N.A., Walter, A., Wilson, A., Siddiqui, T., Roxburgh, C.S.D. , McMillan, D.C. and Guthrie, G.J.K. (2023) The prognostic value of pre-operative systemic inflammation-based scoring in patients undergoing endovascular repair of AAA. Journal of Vascular Surgery, 78(2), 362-369.e2. (doi: 10.1016/j.jvs.2023.04.018) (PMID:37086821)

Bradley, N. A., Walter, A., Dolan, R. , Wilson, A., Siddiqui, T., Roxburgh, C. S.D. , McMillan, D. C. and Guthrie, G. J.K. (2023) Evaluation of the prognostic value of computed tomography-derived body composition in patients undergoing endovascular aneurysm repair. Journal of Cachexia, Sarcopenia and Muscle, 14(4), pp. 1836-1847. (doi: 10.1002/jcsm.13262) (PMID:37221439) (PMCID:PMC10401537)

McGovern, J., Dolan, R. D. and McMillan, D. C. (2023) Assessment and prognostic value of inflammatory biomarkers in patients with colon cancer. JAMA Oncology, 9(8), pp. 1152-1153. (doi: 10.1001/jamaoncol.2023.1529) (PMID:37318817)

McGovern, J., Dolan, R. D. , Simmons, C., Daly, L. E., Ryan, A. M., Power, D. G., Fallon, M. T., Laird, B. J. and McMillan, D. C. (2023) Are CT-Derived Muscle Measurements Prognostic, Independent of Systemic Inflammation, in Good Performance Status Patients with Advanced Cancer? Cancers, 15(13), 3497. (doi: 10.3390/cancers15133497) (PMID:37444607) (PMCID:PMC10340321)

Hatthakarnkul, P. et al. (2023) Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer. Journal of Cancer, 14(10), pp. 1837-1847. (doi: 10.7150/jca.83910) (PMID:37476187) (PMCID:PMC10355195)

Pennel, K., Morrow, E., Hatthakarnkul, P., Leslie, H. , Mallon, E., Andersen, D., Jamieson, N. , McMillan, D. , Roseweir, A. and Edwards, J. (2023) High expression of STAT3 within the tumour-associated stroma predicts poor outcome in breast cancer patients. Cancer Medicine, 12(12), pp. 13225-13240. (doi: 10.1002/cam4.6014) (PMID:37199043) (PMCID:PMC10315752)

McGovern, J., Leadbitter, S., Miller, G., Hounat, A., Kamande, I., Dolan, R. D. , Horgan, P. G. , Chang, D. K. , Jamieson, N. B. and McMillan, D. C. (2023) The relationship between heart rate variability and TNM stage, co-morbidity, systemic inflammation and survival in patients with primary operable colorectal cancer. Scientific Reports, 13, 8157. (doi: 10.1038/s41598-023-35396-x) (PMID:37208421) (PMCID:PMC10198985)

Brown, L. R. et al. (2023) The impact of acute systemic inflammation secondary to oesophagectomy and anastomotic leak on computed tomography body composition analyses. Cancers, 15(9), 2577. (doi: 10.3390/cancers15092577) (PMID:37174044) (PMCID:PMC10177546)

McGovern, J. et al. (2023) The relationship between micronutrient status, frailty, systemic inflammation, and clinical outcomes in patients admitted to hospital with COVID-19. Journal of Translational Medicine, 21, 284. (doi: 10.1186/s12967-023-04138-y) (PMID:37118813) (PMCID:PMC10139911)

Shamis, S. A.K., Edwards, J. and McMillan, D. C. (2023) The relationship between carbonic anhydrase IX (CAIX) and patient survival in breast cancer: systematic review and meta-analysis. Diagnostic Pathology, 18, 46. (doi: 10.1186/s13000-023-01325-9) (PMID:37061698) (PMCID:PMC10105416)

Wood, C. S. et al. (2023) Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases. Cancer Research, 83(8), pp. 1329-1344. (doi: 10.1158/0008-5472.CAN-22-2794) (PMID:37057593) (PMCID:PMC10102851)

Rocha, B. M.M., Dolan, R. D. , Paiva, C. E., McGovern, J., Paiva, B. S. R., Preto, D. D., McMillan, D. C. , Maia, Y. C. P. and Laird, B. J. (2023) Inflammation and performance status: the cornerstones of prognosis in advanced cancer. Journal of Pain and Symptom Management, 65(4), pp. 348-357. (doi: 10.1016/j.jpainsymman.2022.11.021) (PMID:36493981)

McGovern, J., Dolan, R. D. , Simmons, C. P.L., Daly, L. E., Ryan, A. M., Power, D. G., Maguire, D., Fallon, M. T., Laird, B. J. and McMillan, D. C. (2023) Lactate dehydrogenase: relationship with the diagnostic GLIM criterion for cachexia in patients with advanced cancer. British Journal of Cancer, 128(5), pp. 760-765. (doi: 10.1038/s41416-022-02099-5) (PMID:36517550) (PMCID:PMC9977728)

Alexander, P.G., van Wyk, H.C. , Pennel, K.A.F., Hay, J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S.D. , Edwards, J. and Park, J.H. (2023) The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer. British Journal of Cancer, 128(4), pp. 556-567. (doi: 10.1038/s41416-022-02069-x) (PMID:36476660) (PMCID:PMC9938140)

McGovern, J., Grayston, A., Coates, D., Leadbitter, S., Hounat, A., Horgan, P. G. , Dolan, R. D. and McMillan, D. C. (2023) The relationship between the modified frailty index score (mFI-5), malnutrition, body composition, systemic inflammation and short-term clinical outcomes in patients undergoing surgery for colorectal cancer. BMC Geriatrics, 23, 9. (doi: 10.1186/s12877-022-03703-2) (PMID:36609242) (PMCID:PMC9817261)

McGovern, J. et al. (2023) The relationship between computed tomography-derived sarcopenia, cardiopulmonary exercise testing performance, systemic inflammation, and survival in good performance status patients with oesophago-gastric cancer undergoing neoadjuvant treatment. JCSM Clinical Reports, 8(1), pp. 3-11. (doi: 10.1002/crt2.57)

2022

Golder, A. M. , Sin, L. K. E., Alani, F., Dolan, R. , Mansouri, D. , Horgan, P. G. , McMillan, D. C. and Roxburgh, C. S. (2022) The relationship between the mode of presentation, CT-derived body composition, systemic inflammatory grade and survival in colon cancer. Journal of Cachexia, Sarcopenia and Muscle, 13(6), pp. 2863-2874. (doi: 10.1002/jcsm.13097) (PMID:36218135) (PMCID:PMC9745485)

Savioli, F., Morrow, E. S., Dolan, R. D. , Romics, L., Lannigan, A., Edwards, J. and McMillan, D. C. (2022) Prognostic role of preoperative circulating systemic inflammatory response markers in primary breast cancer: meta-analysis. British Journal of Surgery, 109(12), pp. 1206-1215. (doi: 10.1093/bjs/znac319) (PMID:36130112)

Pennel, K. A. F. et al. (2022) CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer. Journal of Pathology: Clinical Research, 8(6), pp. 509-520. (doi: 10.1002/cjp2.290) (PMID:35879507) (PMCID:PMC9535100)

Bradley, N.A., Roxburgh, C.S.D. , McMillan, D.C. and Guthrie, G.J.K. (2022) The relationship between pre-operative psoas and skeletal muscle parameters and survival following endovascular aneurysm repair: a systematic review and meta-analysis. Scientific Reports, 12, 16663. (doi: 10.1038/s41598-022-20490-3) (PMID:36198699) (PMCID:PMC9534993)

Fuglestad, A. J., Meltzer, S., Ree, A. H., McMillan, D. C. , Park, J. H. and Kersten, C. (2022) The clinical value of C-reactive protein and its association with tumour location in patients undergoing curative surgery for colorectal cancer – a ScotScan collaborative study. Acta Oncologica, 61(10), pp. 1248-1255. (doi: 10.1080/0284186X.2022.2117572) (PMID:36068730)

Golder, A.M. , Mshihadani, A., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and Mansouri, D. (2022) Route to diagnosis of colorectal cancer and association with survival within the context of a bowel screening programme. Public Health, 211, pp. 53-61. (doi: 10.1016/j.puhe.2022.06.032) (PMID:36027788)

McGovern, J., Dolan, R. D. , Maguire, D., Horgan, P. , Laird, B. J. and McMillan, D. C. (2022) A comparison of CT-body composition measurements in non-cancer and cancer patients from a single UK centre. Journal of Frailty, Sarcopenia and Falls, 7(3), pp. 117-122. (doi: 10.22540/JFSF-07-117) (PMID:36119551) (PMCID:PMC9433946)

Alexander, P. G. et al. (2022) The relationship between the Glasgow Microenvironment Score and markers of epithelial-mesenchymal transition in TNM II-III colorectal cancer. Human Pathology, 127, pp. 1-11. (doi: 10.1016/j.humpath.2022.05.012) (PMID:35623467)

Cheong, C. M., Golder, A. , Horgan, P. , Roxburgh, C. and McMillan, D. (2022) Relationship between pre‑operative glycated haemoglobin and surgical site infection in patients undergoing elective colon cancer surgery. Oncology Letters, 24(3), 296. (doi: 10.3892/ol.2022.13416) (PMID:35949622) (PMCID:PMC9353220)

McGovern, J., Dolan, R. D. , Skipworth, R. J., Laird, B. J. and McMillan, D. C. (2022) Cancer cachexia: a nutritional or a systemic inflammatory syndrome? British Journal of Cancer, 127, pp. 379-382. (doi: 10.1038/s41416-022-01826-2) (PMID:35523879) (PMCID:PMC9073809)

Di Rollo, D. G., McGovern, J., Morton, C., Miller, G., Dolan, R. , Horgan, P. G. , McMillan, D. C. and Mansouri, D. (2022) Relationship between BMI, CT-derived body composition and colorectal neoplasia in a bowel screening population. Scottish Medical Journal, 67(3), pp. 93-102. (doi: 10.1177/00369330221102237) (PMID:35603880)

McGovern, J., Golder, A. M. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2022) The combination of computed tomography-derived muscle mass and muscle density and relationship with clinicopathological characteristics and survival in patients undergoing potentially curative surgery for colorectal cancer. JCSM Clinical Reports, 7(3), pp. 65-76. (doi: 10.1002/crt2.54)

Shamis, S. A.K., Quinn, J. , Mallon, E. E.A., Edwards, J. and McMillan, D. C. (2022) The relationship between the tumor cell expression of hypoxic markers and survival in patients with ER-positive invasive ductal breast cancer. Journal of Histochemistry and Cytochemistry, 70(7), pp. 479-494. (doi: 10.1369/00221554221110280) (PMID:35792080)

Patel, M. et al. (2022) Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer. British Journal of Cancer, 126(12), pp. 1704-1714. (doi: 10.1038/s41416-022-01729-2) (PMID:35173303) (PMCID:PMC9174220)

Maguire, D. et al. (2022) Randomised trial of intravenous thiamine and/or magnesium sulphate administration on erythrocyte transketolase activity, lactate concentrations and alcohol withdrawal scores. Scientific Reports, 12, 6941. (doi: 10.1038/s41598-022-10970-x) (PMID:35484175) (PMCID:PMC9051209)

Ross, F. A., Park, J. H. , Mansouri, D. , Combet, E. , Horgan, P. G. , McMillan, D. C. and Roxburgh, C. S.D. (2022) The role of faecal calprotectin in diagnosis and staging of colorectal neoplasia: a systematic review and meta-analysis. BMC Gastroenterology, 22, 176. (doi: 10.1186/s12876-022-02220-1) (PMID:35397505) (PMCID:PMC8994317)

Hatthakarnkul, P., Quinn, J. A. , Ammar, A. , Lynch, G., Van Wyk, H. , McMillan, D. C. , Thuwajit, C. and Edwards, J. (2022) Molecular mechanisms of tumour budding and its association with microenvironment in colorectal cancer. Clinical Science, 136(8), pp. 521-535. (doi: 10.1042/CS20210886) (PMID:35445707)

McGovern, J., Dolan, R. D. , Horgan, P. G. , Laird, B. J. and McMillan, D. C. (2022) The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review. BMC Geriatrics, 22, 260. (doi: 10.1186/s12877-022-02928-5) (PMID:35351011) (PMCID:PMC8962494)

Golder, A. M. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S.D. (2022) Determinants of emergency presentation in patients with colorectal cancer: a systematic review and meta-analysis. Scientific Reports, 12, 4366. (doi: 10.1038/s41598-022-08447-y) (PMID:35288664) (PMCID:PMC8921241)

Ross, F. A., Park, J. H. , Mansouri, D. , Little, C., Di Rollo, D. G., Combet, E. , Van Wyk, H. , Horgan, P. G. , McMillan, D. C. and Roxburgh, C. S. D. (2022) The role of faecal calprotectin in the identification of colorectal neoplasia in patients attending for screening colonoscopy. Colorectal Disease, 24(2), pp. 188-196. (doi: 10.1111/codi.15942) (PMID:34614299)

McGovern, J., Al-Azzawi, Y., Kemp, O., Moffitt, P., Richards, C., Dolan, R. D. , Laird, B. J., McMillan, D. C. and Maguire, D. (2022) The relationship between frailty, nutritional status, co-morbidity, CT-body composition and systemic inflammation in patients with COVID-19. Journal of Translational Medicine, 20, 98. (doi: 10.1186/s12967-022-03300-2) (PMID:35189900) (PMCID:PMC8860274)

Cheong, C. M., Golder, A. M. , Horgan, P. D. , McMillan, D. C. and Roxburgh, C. S.D. (2022) Evaluation of clinical prognostic variables on short-term outcome for colorectal cancer surgery: an overview and minimum dataset. Cancer Treatment and Research Communications, 31, 100544. (doi: 10.1016/j.ctarc.2022.100544) (PMID:35248885)

2021

Patton, R., Cook, J., Haraldsdottir, E., Brown, D., Dolan, R. D. , McMillan, D. C. , Skipworth, R. J. E., Fallon, M. and Laird, B. J.A. (2021) REVOLUTION (Routine EValuatiOn of people LivIng with caNcer)—protocol for a prospective characterisation study of patients with incurable cancer. PLoS ONE, 16(12), e0261175. (doi: 10.1371/journal.pone.0261175) (PMID:34914733) (PMCID:PMC8675681)

McGovern, J., Dolan, R. D. , Horgan, P. G. , Laird, B. J. and McMillan, D. C. (2021) Computed tomography-defined low skeletal muscle index and density in cancer patients: observations from a systematic review. Journal of Cachexia, Sarcopenia and Muscle, 12(6), pp. 1408-1417. (doi: 10.1002/jcsm.12831) (PMID:34664431) (PMCID:PMC8718024)

Knight, K. A., Drami, I., McMillan, D. C. , Horgan, P. G. , Park, J. H. , Jenkins, J. T. and Roxburgh, C. S.D. (2021) Vascular calcification and response to neoadjuvant therapy in locally advanced rectal cancer: an exploratory study. Journal of Cancer Research and Clinical Oncology, 147(11), pp. 3409-3420. (doi: 10.1007/s00432-021-03570-1) (PMID:33710416) (PMCID:PMC8484095)

McGovern, J., Dolan, R. , Richards, C., Laird, B. J., McMillan, D. C. and Maguire, D. (2021) Relation between body composition, systemic inflammatory response, and clinical outcomes in patients admitted to an urban teaching hospital with COVID-19. Journal of Nutrition, 151(8), pp. 2236-2244. (doi: 10.1093/jn/nxab142) (PMID:34159388) (PMCID:PMC8195217)

Haq, M. I. et al. (2021) Effect of hepatocellular carcinoma surveillance programmes on overall survival in a mixed cirrhotic UK population: a prospective, longitudinal cohort study. Journal of Clinical Medicine, 10(13), 2770. (doi: 10.3390/jcm10132770) (PMID:34202593) (PMCID:PMC8269358)

Johnstone, M. S., McMillan, D. C. , Horgan, P. G. and Mansouri, D. (2021) The relationship between co-morbidity, screen-detection and outcome in patients undergoing resection for colorectal cancer. World Journal of Surgery, 45(7), pp. 2251-2260. (doi: 10.1007/s00268-021-06079-3) (PMID:33774690) (PMCID:PMC8154830)

Mansouri, D. , McSorley, S. T. , Park, J. H. , Orange, C., Horgan, P. G. , McMillan, D. C. and Edwards, J. (2021) The inflammatory microenvironment in screen-detected premaligant adenomatous polyps: early results from the integrated technologies for improved polyp surveillance (INCISE) project. European Journal of Gastroenterology and Hepatology, 33(7), pp. 983-989. (doi: 10.1097/MEG.0000000000002202) (PMID:34034277)

Matly, A., Quinn, J. A. , McMillan, D. C. , Park, J. H. and Edwards, J. (2021) The relationship between β-catenin and patient survival in colorectal cancer systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 163, 103337. (doi: 10.1016/j.critrevonc.2021.103337) (PMID:33992802)

Knight, K. A., Hon Fei, C., Boland, K. F., Dolan, D. R., Golder, A. M. , McMillan, D. C. , Horgan, P. G. , Black, D. H., Park, J. H. and Roxburgh, C. S.D. (2021) Aortic calcification is associated with non-infective rather than infective postoperative complications following colorectal cancer resection: an observational cohort study. European Radiology, 31(6), pp. 4319-4329. (doi: 10.1007/s00330-020-07189-7) (PMID:33201280)

Maguire, D. et al. (2021) The relation between acute changes in the systemic inflammatory response and circulating thiamine and magnesium concentrations after elective knee arthroplasty. Scientific Reports, 11, 11271. (doi: 10.1038/s41598-021-90591-y) (PMID:34050237) (PMCID:PMC8163855)

Maguire, D. et al. (2021) The systemic inflammatory response and clinicopathological characteristics in patients admitted to hospital with COVID-19 infection: comparison of 2 consecutive cohorts. PLoS ONE, 16(5), e0251924. (doi: 10.1371/journal.pone.0251924) (PMID:34043668) (PMCID:PMC8159002)

Kyle, D., Shaw, M., Maguire, D., McMillan, D. , Quasim, T. , Leyland, A. H. and McPeake, J. (2021) The wider implications of the COVID-19 pandemic: assessing the impact of accident and emergency use for frequent attenders. International Emergency Nursing, 56, 100984. (doi: 10.1016/j.ienj.2021.100984) (PMID:33677141) (PMCID:PMC7896822)

Al-Badran, S. S.F. et al. (2021) Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer. Journal of Pathology: Clinical Research, 7(2), pp. 121-134. (doi: 10.1002/cjp2.193) (PMID:33338327)

Shamis, S. A. K., McMillan, D. C. and Edwards, J. (2021) The relationship between Hypoxia-inducible factor 1α (HIF-1α) and patient survival in breast cancer: systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 159, 103231. (doi: 10.1016/j.critrevonc.2021.103231) (PMID:33482350)

Alexander, P.G. et al. (2021) The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. British Journal of Cancer, 124, pp. 786-796. (doi: 10.1038/s41416-020-01168-x) (PMID:33223535)

McSorley, S. T. , Lau, H. Y.N., McIntosh, D., Forshaw, M. J., McMillan, D. C. and Crumley, A. B. (2021) Staging the tumour and staging the host: Pre-treatment combined Neutrophil Lymphocyte Ratio and modified Glasgow Prognostic Score is associated with overall survival in patients with oesophagogastric cancers undergoing treatment with curative intent. Annals of Surgical Oncology, 28(2), pp. 722-731. (doi: 10.1245/s10434-020-09074-5) (PMID:32892266) (PMCID:PMC7801291)

Alhayyan, A. M. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2021) The effect of anesthesia on the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colorectal cancer in the context of an enhanced recovery pathway: A prospective cohort study. Medicine, 100(2), e23997. (doi: 10.1097/MD.0000000000023997) (PMID:33466141) (PMCID:PMC7808526)

Alexander, P. G., McMillan, D. C. and Park, J. H. (2021) A meta-analysis of CD274 (PD-L1) assessment and prognosis in colorectal cancer and its role in predicting response to anti-PD-1 therapy. Critical Reviews in Oncology/Hematology, 157, p. 103147. (doi: 10.1016/j.critrevonc.2020.103147) (PMID:33278675)

Knight, K., Choong, J.X., McKee, R.F., Anderson, J.H., Horgan, P.G. , McMillan, D.C. , McDonald, A. and Roxburgh, C.S. (2021) The influence of systemic inflammation on treatment response and survival in anal squamous cell cancer. Clinical Oncology, 33(1), e22-e30. (doi: 10.1016/j.clon.2020.06.010) (PMID:32709540)

Hatthakarnkul, P., Quinn, J. A. , Matly, A. A. M., Ammar, A. , Van Wyk, H. C. , McMillan, D. C. and Edwards, J. (2021) Systematic review of tumour budding and association with common mutations in patients with colorectal cancer. Critical Reviews in Oncology/Hematology, 167, 103490. (doi: 10.1016/j.critrevonc.2021.103490) (PMID:34619332)

2020

Dolan, R. D. , Maclay, J. D., Abbass, T., Colville, D., Buali, F., MacLeod, N., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2020) The relationship between 18F-FDG-PETCT-derived tumour metabolic activity, nutritional risk, body composition, systemic inflammation and survival in patients with lung cancer. Scientific Reports, 10, 20819. (doi: 10.1038/s41598-020-77269-7) (PMID:33257741) (PMCID:PMC7705735)

Savioli, F., Edwards, J. , McMillan, D. , Stallard, S., Doughty, J. and Romics, L. (2020) The effect of postoperative complications on survival and recurrence after surgery for breast cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 155, 103075. (doi: 10.1016/j.critrevonc.2020.103075) (PMID:32987333)

Dolan, R. D. , Alwahid, M., McSorley, S. T. , Park, J. H. , Stevenson, R. P., Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2020) A comparison of the prognostic value of composite ratios and cumulative scores in patients with operable rectal cancer. Scientific Reports, 10, 17965. (doi: 10.1038/s41598-020-73909-0) (PMID:33087753) (PMCID:PMC7578034)

Abbass, T. , Dolan, R. D. , Horgan, P. G. and McMillan, D. C. (2020) The relationship between systemic inflammation, body composition and clinical outcomes in patients with operable colorectal cancer at low and medium to high nutritional risk. JCSM Clinical Reports, 5(4), pp. 99-107. (doi: 10.1002/crt2.25)

Roseweir, A. K. et al. (2020) Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. Journal of Pathology: Clinical Research, 6(4), pp. 283-296. (doi: 10.1002/cjp2.171) (PMID:32401426) (PMCID:PMC7578335)

Maguire, D. et al. (2020) Prognostic factors in patients admitted to an urban teaching hospital with COVID-19 infection. Journal of Translational Medicine, 18, 354. (doi: 10.1186/s12967-020-02524-4) (PMID:32933530) (PMCID:PMC7491021)

Dolan, R. D. , Daly, L., Sim, W. M.J., Fallon, M., Ryan, A., McMillan, D. C. and Laird, B. J. (2020) Comparison of the prognostic value of ECOG-PS, mGPS and BMI/WL: implications for a clinically important framework in the assessment and treatment of advanced cancer. Clinical Nutrition, 39(9), pp. 2889-2895. (doi: 10.1016/j.clnu.2019.12.024) (PMID:31926762)

Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2020) Authors' reply: Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short-term outcomes following left-sided colonic and rectal resections. BJS Open, 4(4), pp. 730-731. (doi: 10.1002/bjs5.50286) (PMID:32297454) (PMCID:PMC7397349)

Park, J. H. , Fuglestad, A. J., Køstner, A. H., Oliwa, A., Graham, J., Horgan, P. G. , Roxburgh, C. S.D. , Kersten, C. and McMillan, D. C. (2020) Systemic inflammation and outcome in 2295 patients with stage I-III colorectal cancer from Scotland and Norway: First results from the ScotScan Colorectal Cancer Group. Annals of Surgical Oncology, 27, pp. 2784-2794. (doi: 10.1245/s10434-020-08268-1) (PMID:32248375) (PMCID:PMC7334267)

Almasaudi, A. S., Dolan, R. D. , Edwards, C. A. and McMillan, D. C. (2020) Hypoalbuminemia reflects nutritional risk, body composition and systemic inflammation and is independently associated with survival in patients with colorectal cancer. Cancers, 12(7), 1986. (doi: 10.3390/cancers12071986)

Dolan, R. D. , Tien, Y.-T., Horgan, P. G. , Edwards, C. A. and McMillan, D. C. (2020) The relationship between computed tomography‐derived body composition and survival in colorectal cancer: the effect of image software. Journal of Cachexia, Sarcopenia and Muscle: Rapid Communications, 3(2), pp. 81-90. (doi: 10.1002/rco2.15)

Daly, L. E. et al. (2020) Determinants of quality of life in patients with incurable cancer. Cancer, 126(12), pp. 2872-2882. (doi: 10.1002/cncr.32824) (PMID:32267548)

McSorley, S. T. , Anderson, J. H., Whittle, T., Roxburgh, C. S. , Horgan, P. G. , McMillan, D. C. and Steele, C. W. (2020) The impact of preoperative systemic inflammation on the efficacy of intravenous iron infusion to correct anaemia prior to surgery for colorectal cancer. Perioperative Medicine, 9, 17. (doi: 10.1186/s13741-020-00146-4) (PMID:32537137) (PMCID:PMC7288411)

Dolan, R. and McMillan, D. C. (2020) The prevalence of cancer associated systemic inflammation: Implications of prognostic studies using the Glasgow Prognostic Score. Critical Reviews in Oncology/Hematology, 150, 102962. (doi: 10.1016/j.critrevonc.2020.102962) (PMID:32344318)

Dolan, R. D. et al. (2020) The relationship between ECOG-PS, mGPS, BMI/WL grade and body composition and physical function in patients with advanced cancer. Cancers, 12(5), 1187. (doi: 10.3390/cancers12051187) (PMID:32397102) (PMCID:PMC7281405)

ALHAYYAN, A. , McSorley, S. T. , Kearns, R. J. , Horgan, P. G. , Roxburgh, C. S.D. and McMillan, D. C. (2020) The relationship between anaesthetic technique, clinicopathological characteristics and the magnitude of the postoperative systemic inflammatory response in patients undergoing elective surgery for colon cancer. PLoS ONE, 15(4), e0228580. (doi: 10.1371/journal.pone.0228580) (PMID:32348308) (PMCID:PMC7190171)

Okugawa, Y. et al. (2020) Lymphocyte-to-C-reactive protein ratio and score are clinically feasible nutrition-inflammation markers of outcome in patients with gastric cancer. Clinical Nutrition, 39(4), pp. 1209-1217. (doi: 10.1016/j.clnu.2019.05.009) (PMID:31155370)

Alexander, P. G., McMillan, D. C. and Park, J. H. (2020) The local inflammatory response in colorectal cancer – type, location or density? A systematic review and meta-analysis. Cancer Treatment Reviews, 83, 101949. (doi: 10.1016/j.ctrv.2019.101949) (PMID:31869737)

Daly, L. et al. (2020) The relationship between the BMI-adjusted weight loss grading system and quality of life in patients with incurable cancer. Journal of Cachexia, Sarcopenia and Muscle, 11(1), pp. 160-168. (doi: 10.1002/jcsm.12499) (PMID:31692296) (PMCID:PMC7015235)

Alhayyan, A. , McSorley, S. , Roxburgh, C. , Kearns, R. , Horgan, P. and McMillan, D. (2020) The effect of anesthesia on the postoperative systemic inflammatory response in patients undergoing surgery: a systematic review and meta-analysis. Surgery Open Science, 2(1), pp. 1-21. (doi: 10.1016/j.sopen.2019.06.001) (PMID:32754703) (PMCID:PMC7391900)

Knight, K.A., Horgan, P.G. , McMillan, D.C. , Roxburgh, C.S.D. and Park, J.H. (2020) The relationship between aortic calcification and anastomotic leak following gastrointestinal resection: a systematic review. International Journal of Surgery, 73, pp. 42-49. (doi: 10.1016/j.ijsu.2019.11.023) (PMID:31765846)

McSorley, S. T. , Tham, A., Dolan, R. D. , Steele, C. W. , Ramsingh, J., Roxburgh, C. , Horgan, P. G. and McMillan, D. C. (2020) Perioperative blood transfusion is associated with the postoperative systemic inflammatory response and poorer outcomes following surgery for colorectal cancer. Annals of Surgical Oncology, 27, pp. 833-843. (doi: 10.1245/s10434-019-07984-7) (PMID:31664621) (PMCID:PMC7000540)

2019

Almasaudi, A. S., McSorley, S. T. , Dolan, R. D. , Edwards, C. A. and McMillan, D. C. (2019) The relation between Malnutrition Universal Screening Tool (MUST), computed tomography-derived body composition, systemic inflammation, and clinical outcomes in patients undergoing surgery for colorectal cancer. American Journal of Clinical Nutrition, 110(6), pp. 1327-1334. (doi: 10.1093/ajcn/nqz230) (PMID:31529042)

Golder, A.M. , Steele, C.W. , Conn, D., Mackay, G.J., McMillan, D.C. , Horgan, P.G. , Roxburgh, C.S. and McSorley, S.T. (2019) Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short‐term outcomes following left‐sided colonic and rectal resections. BJS Open, 3(6), pp. 830-839. (doi: 10.1002/bjs5.50224) (PMID:31832590) (PMCID:PMC6887908)

Golder, A. M. , McSorley, S. T. , Kearns, R. J. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S. (2019) Attitudes towards the use of perioperative steroids in resectional colorectal cancer surgery in the UK: a qualitative study. Annals of Medicine and Surgery, 48, pp. 23-28. (doi: 10.1016/j.amsu.2019.10.007) (PMID:31687135) (PMCID:PMC6820077)

Maguire, D. et al. (2019) A prospective evaluation of thiamine and magnesium status in relation to clinicopathological characteristics and 1-year mortality in patients with Alcohol Withdrawal Syndrome. Journal of Translational Medicine, 17, 384. (doi: 10.1186/s12967-019-02141-w) (PMID:31752901) (PMCID:PMC6873772)

Almasaudi, A. S., Dolan, R. D. , McSorley, S. T. , Horgan, P. G. , Edwards, C. and McMillan, D. C. (2019) Relationship between computed tomography-derived body composition, sex, and post-operative complications in patients with colorectal cancer. European Journal of Clinical Nutrition, 73(11), pp. 1450-1457. (doi: 10.1038/s41430-019-0414-0) (PMID:30858540)

Abbass, T. , Dolan, R. D. , Laird, B. J. and McMillan, D. C. (2019) The relationship between imaging-based body composition analysis and the systemic inflammatory response in patients with cancer: a systematic review. Cancers, 11, 1304. (doi: 10.3390/cancers11091304) (PMID:31487957)

Park, J. H. , van Wyk, H. , McMillan, D. C. , Edwards, J. , Orange, C., Horgan, P. G. and Roxburgh, C. S.D. (2019) Pre-operative, biopsy-based assessment of the tumour microenvironment in patients with primary operable colorectal cancer. Journal of Pathology: Clinical Research, 6(1), pp. 30-39. (doi: 10.1002/cjp2.143) (PMID:31486287) (PMCID:PMC6966701)

McSorley, S. T. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. , MacKay, G. J. and McMillan, D. C. (2019) Possible dose dependent effect of perioperative dexamethasone and laparoscopic surgery on the postoperative systemic inflammatory response and complications following surgery for colon cancer. European Journal of Surgical Oncology, 45(9), pp. 1613-1618. (doi: 10.1016/j.ejso.2019.05.020) (PMID:31130339)

Park, J. H. , Woodley, N., McMillan, D. C. and Glen, P. (2019) Palliative stenting for oesophagogastric cancer: tumour and host factors and prognosis. BMJ Supportive and Palliative Care, 9, pp. 332-339. (doi: 10.1136/bmjspcare-2017-001490) (PMID:29574423)

Maguire, D. et al. (2019) Low serum magnesium and 1-year mortality in alcohol withdrawal syndrome. European Journal of Clinical Investigation, 49(9), e13152. (doi: 10.1111/eci.13152) (PMID:31216056)

Simmons, C. et al. (2019) "How long have I got?" - A prospective cohort study comparing validated prognostic factors for use in patients with advanced cancer. Oncologist, 24(9), e960-e967. (doi: 10.1634/theoncologist.2018-0474) (PMID:30975922)

Andisha, N. M., McMillan, D. C. , Gujam, F. J.A., Roseweir, A. and Edwards, J. (2019) The relationship between phosphorylation status of focal adhesion kinases, molecular subtypes, tumour microenvironment and survival in patients with primary operable ductal breast cancer. Cellular Signalling, 60, pp. 91-99. (doi: 10.1016/j.cellsig.2019.04.006) (PMID:30981841)

McSorley, S. T. , Tham, A., Steele, C. W. , Dolan, R. D. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2019) Quantitative data on red cell measures of iron status and their relation to the magnitude of the systemic inflammatory response and survival in patients with colorectal cancer. European Journal of Surgical Oncology, 45(7), pp. 1205-1211. (doi: 10.1016/j.ejso.2019.02.027) (PMID:30850153)

Okugawa, Y. et al. (2019) Circulating miR-203 derived from metastatic tissues promotes myopenia in colorectal cancer patients. Journal of Cachexia, Sarcopenia and Muscle, 10, pp. 536-548. (doi: 10.1002/jcsm.12403) (PMID:31091026) (PMCID:PMC6596405)

Roseweir, A. K. , Clark, J., McSorley, S. T. , vanWyk, H. C. , Quinn, J. A. , Horgan, P. G. , McMillan, D. C. , Park, J. H. and Edwards, J. (2019) The association between markers of tumour cell metabolism, the tumour microenvironment and outcomes in patients with colorectal cancer. International Journal of Cancer, 144(9), pp. 2320-2329. (doi: 10.1002/ijc.32045) (PMID:30521130)

McSorley, S. T. , Tham, A., Jones, I., Talwar, D. and McMillan, D. C. (2019) Regression correction equation to adjust serum iron and ferritin concentrations based on C-reactive protein and albumin in patients receiving primary and secondary care. Journal of Nutrition, 149(5), pp. 877-883. (doi: 10.1093/jn/nxz008) (PMID:31050746)

Okugawa, Y. et al. (2019) Close relationship between immunological/inflammatory markers and myopenia and myosteatosis in patients With colorectal cancer: A Propensity score matching analysis. Journal of Parenteral and Enteral Nutrition, 43(4), pp. 508-515. (doi: 10.1002/jpen.1459) (PMID:30334265)

Dolan, R. D. , McLees, N. G., Irfan, A., McSorley, S. T. , Horgan, P. G. , Colville, D. and McMillan, D. C. (2019) The relationship between tumour glucose metabolism and host systemic inflammatory responses in patients with cancer: a systematic review. Journal of Nuclear Medicine, 60(4), pp. 467-471. (doi: 10.2967/jnumed.118.216697) (PMID:30166353)

Almasaudi, A. S., McSorley, S. T. , Horgan, P. G. , McMillan, D. C. and Edwards, C. A. (2019) The relationship between body mass index, sex, and postoperative outcomes in patients undergoing potentially curative surgery for colorectal cancer. Clinical Nutrition ESPEN, 30, pp. 185-189. (doi: 10.1016/j.clnesp.2018.12.084) (PMID:30904219)

Roseweir, A. K. , Powell, A. G.M.T., Horstman, S. L., Inthagard, J., Park, J. A. , McMillan, D. C. , Horgan, P. G. and Edwards, J. (2019) Src family kinases, HCK and FGR, associate with local inflammation and tumour progression in colorectal cancer. Cellular Signalling, 56, pp. 15-22. (doi: 10.1016/j.cellsig.2019.01.007) (PMID:30684564)

McSorley, S. , Johnstone, M., Steele, C. W. , Roxburgh, C. S.D. , Horgan, P. G. , McMillan, D. C. and Mansouri, D. (2019) Normocytic anaemia is associated with systemic inflammation and poorer survival in patients with colorectal cancer treated with curative intent. International Journal of Colorectal Disease, 34(3), pp. 401-408. (doi: 10.1007/s00384-018-3211-7) (PMID:30515556)

Dolan, R. , Almasaudi, A. S., Dieu, L. B., Horgan, P. G. , McSorley, S. T. and McMillan, D. C. (2019) The relationship between computed tomography‐derived body composition, systemic inflammatory response, and survival in patients undergoing surgery for colorectal cancer. Journal of Cachexia, Sarcopenia and Muscle, 10(1), pp. 111-122. (doi: 10.1002/jcsm.12357) (PMID:30460764) (PMCID:PMC6438413)

Pennel, K. A.F., Park, J. H. , McMillan, D. C. , Roseweir, A. K. and Edwards, J. (2019) Signal interaction between the tumour and inflammatory cells in patients with gastrointestinal cancer: implications for treatment. Cellular Signalling, 54, pp. 81-90. (doi: 10.1016/j.cellsig.2018.11.013) (PMID:30453014)

Roseweir, A.K. et al. (2019) A novel tumor-based epithelial-to-mesenchymal transition score that associates with prognosis and metastasis in patients with stage II/III colorectal cancer. International Journal of Cancer, 144(1), pp. 150-159. (doi: 10.1002/ijc.31739) (PMID:29992570)

Daly, L.E. et al. (2019) Clinical & Nutritional Determinants of Quality of Life in Patients with Incurable Cancer. 44th ESMO Congress (ESMO 2019), Barcelona, Spain, 27 Sep - 1 Oct 2019.

Sullivan, E.S., Daly, L.E., Dolan, R. , Ní Bhuachalla, É.B., Fallon, M., Simmons, C., McMillan, D.C. , Laird, B., Ryan, A.M. and Power, D.G. (2019) Predictors of Survival in Patients with Incurable Cancer. 44th ESMO Congress (ESMO 2019), Barcelona, Spain, 27 Sep - 1 Oct 2019.

Van Wyk, H. , Roseweir, A. , Alexander, P. , Park, J. H. , Horgan, P. , McMillan, D. and Edwards, J. (2019) The relationship between tumour budding, tumour microenvironment and survival in patients with primary operable colorectal cancer. Annals of Surgical Oncology, 26, pp. 4397-4404. (doi: 10.1245/s10434-019-07931-6) (PMID:31605345) (PMCID:PMC6863941)

2018

Dolan, R. D. , Laird, B., Horgan, P. G. and McMillan, D. C. (2018) The prognostic value of the systemic inflammatory response in randomised clinical trials in cancer: A systematic review. Critical Reviews in Oncology/Hematology, 132, pp. 130-137. (doi: 10.1016/j.critrevonc.2018.09.016)

Okugawa, Y. et al. (2018) Clinical impact of muscle quantity and quality in colorectal cancer patients: a propensity score matching analysis. Journal of Parenteral and Enteral Nutrition, 42(8), pp. 1322-1333. (doi: 10.1002/jpen.1171) (PMID:29761898)

Hishida, A. et al. (2018) Genetic influence of cytokine polymorphisms on the clinical outcome of Japanese gastrointestinal cancer patients in palliative care. Oncology Letters, 17(1), pp. 623-629. (doi: 10.3892/ol.2018.9614) (PMID:30655809) (PMCID:PMC6313183)

McDonald, J. J., McMillan, D. C. and Laird, B. J. (2018) Targeting IL-1α in cancer cachexia: a narrative review. Current Opinion in Supportive and Palliative Care, 12(4), pp. 453-459. (doi: 10.1097/SPC.0000000000000398) (PMID:30300155)

Roseweir, A. K. , McMillan, D. C. and Edwards, J. (2018) Reply to comment of "ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer". British Journal of Cancer, 119(7), p. 909. (doi: 10.1038/s41416-018-0275-7) (PMID:30297771) (PMCID:PMC6189185)

McMillan, D. C. , Maguire, D. and Talwar, D. (2018) Relationship between nutritional status and the systemic inflammatory response: micronutrients. Proceedings of the Nutrition Society, 78(1), pp. 56-67. (doi: 10.1017/S0029665118002501) (PMID:30220267)

Barroso, T., Conway, F., Emel, S., McMillan, D. , Young, D., Karteszi, H., Gaya, D. R. and Gerasimidis, K. (2018) Patients with inflammatory bowel disease have higher abdominal adiposity and less skeletal mass than healthy controls. Annals of Gastroenterology, 31(5), pp. 566-571. (doi: 10.20524/aog.2018.0280) (PMID:30174393) (PMCID:PMC6102468)

Park, J. H. et al. (2018) Staging the tumor and staging the host: A two centre, two country comparison of systemic inflammatory responses of patients undergoing resection of primary operable colorectal cancer. American Journal of Surgery, 216(3), pp. 458-464. (doi: 10.1016/j.amjsurg.2017.08.044) (PMID:28967380)

McSorley, S. T. , Black, D. H., Horgan, P. G. and McMillan, D. C. (2018) The relationship between tumour stage, systemic inflammation, body composition and survival in patients with colorectal cancer. Clinical Nutrition, 37(4), pp. 1279-1285. (doi: 10.1016/j.clnu.2017.05.017) (PMID:28566220)

Gujam, F., Dickson, K., McCall, P., McMillan, D. and Edwards, J. (2018) The relationship between androgen receptor, components of tumour microenvironment and survival in breast cancer molecular subtypes. Cancer Therapy and Oncology, 11(3), 555814.

Roseweir, A. K. , Halcrow, E. S., Chichilo, S., Powell, A. G.M.T., McMillan, D. C. , Horgan, P. G. and Edwards, J. (2018) ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer. British Journal of Cancer, 119, pp. 323-329. (doi: 10.1038/s41416-018-0174-y) (PMID:29988110) (PMCID:PMC6070918)

Dolan, R. D. , McSorley, S. T. , Park, J. H. , Watt, D. G. , Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2018) The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores. British Journal of Cancer, 119(1), pp. 40-51. (doi: 10.1038/s41416-018-0095-9) (PMID:29789606)

McSorley, S. T. , Talwar, D. and McMillan, D. C. (2018) Comment on the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project. American Journal of Clinical Nutrition, 108(1), pp. 204-205. (doi: 10.1093/ajcn/nqx071) (PMID:29982308)

Park, J.H. , Horgan, P.G. and McMillan, D.C. (2018) In reply to: “Meyer CP, et al. The association of hypoalbuminemia with early perioperative outcomes – A comprehensive assessment across 16 major procedures”. American Journal of Surgery, 216(1), pp. 174-175. (doi: 10.1016/j.amjsurg.2016.12.023) (PMID:28082008)

Patel, M., Horgan, P. G. , McMillan, D. C. and Edwards, J. (2018) NF-κB pathways in the development and progression of colorectal cancer. Translational Research, 197, pp. 43-56. (doi: 10.1016/j.trsl.2018.02.002) (PMID:29550444)

McSorley, S. T. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2018) The relationship between cardiopulmonary exercise test variables, the systemic inflammatory response, and complications following surgery for colorectal cancer. Perioperative Medicine, 7(1), 11. (doi: 10.1186/s13741-018-0093-8) (PMID:29983927) (PMCID:PMC6003031)

Maguire, D., Talwar, D., Shiels, P. G. and McMillan, D. (2018) The role of thiamine dependent enzymes in obesity and obesity related chronic disease states: a systematic review. Clinical Nutrition ESPEN, 25, pp. 8-17. (doi: 10.1016/j.clnesp.2018.02.007) (PMID:29779823)

Roseweir, A. K. et al. (2018) Predictive biomarkers for endocrine therapy: retrospective study in Tamoxifen and Exemestane Adjuvant Multinational (TEAM) trial. Journal of the National Cancer Institute, 110(6), pp. 616-627. (doi: 10.1093/jnci/djx255) (PMID:29917140)

McSorley, S. T. , Khor, B. Y., Tsang, K., Colville, D., Han, S., Horgan, P. G. and McMillan, D. C. (2018) The relationship between 18F FDG-PETCT derived markers of tumour metabolism and systemic inflammation in patients with recurrent disease following surgery for colorectal cancer. Colorectal Disease, 20(5), pp. 407-415. (doi: 10.1111/codi.13973)

Maliampurakal, A. J., McMillan, D. C. , Anderson, J. H., Horgan, P. G. and Mansouri, D. (2018) Factors associated with the efficacy of polyp detection during routine flexible sigmoidoscopy. Frontline Gastroenterology, 9(2), pp. 135-142. (doi: 10.1136/flgastro-2017-100849) (PMID:29588842)

Dolan, R. , McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2018) Determinants of lymph node count and positivity in patients undergoing surgery for colon cancer. Medicine, 97(13), e0185. (doi: 10.1097/MD.0000000000010185) (PMID:29595652) (PMCID:29595652)

McSorley, S. T. , Mansouri, D. , Horgan, P. G. and McMillan, D. C. (2018) Comment on "the important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial". Annals of Surgery, 267(3), e49. (doi: 10.1097/SLA.0000000000002053) (PMID:27759622)

Okugawa, Y. et al. (2018) Clinical burden of modified Glasgow Prognostic Scale in colorectal cancer. Anticancer Research, 38(3), pp. 1599-1610. (doi: 10.21873/anticanres.12390) (PMID:29491091)

Park, J.H. and McMillan, D.C. (2018) Outcome in colorectal cancer – tumour, stroma and so much more. Annals of Oncology, 29(3), pp. 534-535. (doi: 10.1093/annonc/mdy007) (PMID:29324981)

Patel, M., McSorley, S. T. , Park, J. H. , Roxburgh, C. S.D. , Edwards, J. , Horgan, P. G. and McMillan, D. C. (2018) The relationship between right-sided tumour location, tumour microenvironment, systemic inflammation, adjuvant therapy and survival in patients undergoing surgery for colon and rectal cancer. British Journal of Cancer, 118(5), pp. 705-712. (doi: 10.1038/bjc.2017.441) (PMID:29337962) (PMCID:PMC5846060)

Almasaudi, A. S., McSorley, S. T. , Edwards, C. A. and McMillan, D. C. (2018) The relationship between body mass index and short term postoperative outcomes in patients undergoing potentially curative surgery for colorectal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 121, pp. 68-73. (doi: 10.1016/j.critrevonc.2017.12.004) (PMID:29279101)

Maguire, D., Neytchev, O. , Talwar, D., McMillan, D. and Shiels, P. (2018) Telomere homeostasis: interplay with magnesium. International Journal of Molecular Sciences, 19(1), 157. (doi: 10.3390/ijms19010157) (PMID:29303978) (PMCID:PMC5796106)

Dolan, R. , McSorley, S. T. , Park, J. H. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2018) The Prognostic Value of Systemic Inflammation in Patients Undergoing Surgery for Rectal Cancer: Comparison of Composite Ratios and Cumulative Scores. Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 18-20 Jan 2018. (doi: 10.1200/JCO.2018.36.4_suppl.579)

Dolan, R. , Tilling, E., Kong, C. Y. , MacLeod, N. J., McSorley, S. T. , Park, J. H. , Glen, P., Horgan, P. G. , Laird, B. and McMillan, D. C. (2018) Evaluation of Systemic Inflammation Based Prognostic Scores in Patients with Advanced Oesophageal Cancer Receiving Palliative Radiotherapy. Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 18-20 Jan 2018.

2017

Dolan, R. D. , Lim, J., Mcsorley, S. T. , Horgan, P. G. and McMillan, D. C. (2017) The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis. Scientific Reports, 7, 16717. (doi: 10.1038/s41598-017-16955-5) (PMID:29196718) (PMCID:PMC5711862)

Arends, J. et al. (2017) ESPEN expert group recommendations for action against cancer-related malnutrition. Clinical Nutrition, 36(5), pp. 1187-1196. (doi: 10.1016/j.clnu.2017.06.017) (PMID:28689670)

Dolan, R. D. and McMillan, D. C. (2017) Neutrophil-to-lymphocyte ratio as a bladder cancer biomarker: assessing prognostic and predictive value in SWOG 8710. Cancer, 123(19), p. 3855. (doi: 10.1002/cncr.30872) (PMID:28665479)

Dolan, R. D. , McSorley, S. T. , McMillan, D. C. and Horgan, P. G. (2017) Attitudes of surgeons to the use of postoperative markers of the systemic inflammatory response following elective surgery. Annals of Medicine and Surgery, 21, pp. 14-19. (doi: 10.1016/j.amsu.2017.07.046) (PMID:28761641) (PMCID:PMC5524306)

Watt, D. G. , Ramanathan, M. L., McSorley, S. T. , Walley, K., Park, J. H. , Horgan, P. G. and McMillan, D. C. (2017) Clinicopathological determinants of an elevated systemic inflammatory response following elective potentially curative resection for colorectal cancer. Annals of Surgical Oncology, 24(9), pp. 2588-2594. (doi: 10.1245/s10434-017-5987-z) (PMID:28695389) (PMCID:PMC5539269)

Dolan, R. D. , McSorley, S. T. , Horgan, P. G. , Laird, B. and McMillan, D. C. (2017) The role of the systemic inflammatory response in predicting outcomes in patients with advanced inoperable cancer: Systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 116, pp. 134-146. (doi: 10.1016/j.critrevonc.2017.06.002) (PMID:28693795)

Mcsorley, S. T. , Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2017) The impact of preoperative dexamethasone on the magnitude of the postoperative systemic inflammatory response and complications following surgery for colorectal cancer. Annals of Surgical Oncology, 24(8), pp. 2104-2112. (doi: 10.1245/s10434-017-5817-3) (PMID:28251379)

Park, J. H. , Roxburgh, C. S.D. , Edwards, J. , Horgan, P. G. and McMillan, D. C. (2017) In reply to "Hynes S.O. et al. Back to the future: routine morphological assessment of the tumour microenvironment is prognostic in stage II/III colon cancer in a large population-based study". Histopathology, 71(2), pp. 326-327. (doi: 10.1111/his.13195) (PMID:28226191)

Shirai, Y. et al. (2017) Fish oil-enriched nutrition combined with systemic chemotherapy for gastrointestinal cancer patients with cancer cachexia. Scientific Reports, 7, 4826. (doi: 10.1038/s41598-017-05278-0) (PMID:28684736) (PMCID:PMC5500468)

Roseweir, A. K. , McMillan, D. C. , Horgan, P. G. and Edwards, J. (2017) Colorectal cancer subtypes: Translation to routine clinical pathology. Cancer Treatment Reviews, 57, pp. 1-7. (doi: 10.1016/j.ctrv.2017.04.006) (PMID:28505475)

Simmons, C. P., Koinis, F., Fallon, M. T., Fearon, K. C., Bowden, J., Solheim, T. S., Gronberg, B. H., McMillan, D. C. , Gioulbasanis, I. and Laird, B. J. (2017) Corrigendum to "Prognosis in advanced lung cancer - a prospective study examining key clinicopathological factors" [Lung Cancer 88 (2015) 304-309]. Lung Cancer, 108, p. 256. (doi: 10.1016/j.lungcan.2017.04.015) (PMID:28457608)

Park, J.H. , Van Wyk, H. , Roxburgh, C.S.D. , Horgan, P.G. , Edwards, J. and McMillan, D.C. (2017) Tumour invasiveness, the local and systemic environment and the basis of staging systems in colorectal cancer. British Journal of Cancer, 116, pp. 1444-1450. (doi: 10.1038/bjc.2017.108)

Bennett, L., Mallon, E. A., Horgan, P. G. , Paul, A., McMillan, D. C. and Edwards, J. (2017) The relationship between members of the canonical NF-KB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancer. Oncotarget, 8(20), pp. 33002-33013. (doi: 10.18632/oncotarget.16031) (PMID:28423692)

Dreyer, S. B., Powell, A. G.M.T., McSorley, S. T. , Waterston, A., Going, J. J., Edwards, J. , McMillan, D. C. and Horgan, P. G. (2017) The pretreatment systemic inflammatory response is an important determinant of poor pathologic response for patients undergoing neoadjuvant therapy for rectal cancer. Annals of Surgical Oncology, 24(5), pp. 1295-1303. (doi: 10.1245/s10434-016-5684-3) (PMID:27873100)

Morhij, R., Mahendra, A., Jane, M. and McMillan, D. C. (2017) The modified Glasgow prognostic score in patients undergoing surgery for bone and soft tissue sarcoma. Journal of Plastic, Reconstructive and Aesthetic Surgery, 70(5), pp. 618-624. (doi: 10.1016/j.bjps.2017.01.016) (PMID:28342782)

Simmons, C. P.L., McMillan, D. C. , McWilliams, K., Sande, T. A., Fearon, K. C., Tuck, S., Fallon, M. T. and Laird, B. J. (2017) Prognostic tools in patients with advanced cancer: a systematic review. Journal of Pain and Symptom Management, 53(5), 962-970.e10. (doi: 10.1016/j.jpainsymman.2016.12.330) (PMID:28062344)

McSorley, S. T. , Roxburgh, C. S. , Horgan, P. G. and McMillan, D. C. (2017) Re: Dexamethasone versus standard treatment for postoperative nausea and vomiting in gastrointestinal surgery: randomised controlled trial (DREAMS Trial). British Medical Journal, 357, j1455.

Bennett, L., Quinn, J. , McCall, P., Mallon, E. A., Horgan, P. G. , McMillan, D. C. , Paul, A. and Edwards, J. (2017) High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer. International Journal of Cancer, 140(7), pp. 1633-1644. (doi: 10.1002/ijc.30578) (PMID:28006839)

Cheng, K. K.W., Dickson, A., Gujam, F. J.A., McMillan, D. C. and Edwards, J. (2017) The relationship between oestrogen receptor-alpha phosphorylation and the tumour microenvironment in patients with primary operable ductal breast cancer. Histopathology, 70(5), pp. 782-797. (doi: 10.1111/his.13134) (PMID:27891654)

Ghashut, R. A., Blackwell, S., Ryan, S., Willox, L., McMillan, D. C. , Kinsella, J. and Talwar, D. (2017) Assessment of asymmetrical dimethylarginine metabolism in patients with critical illness. European Journal of Clinical Investigation, 47(4), pp. 279-288. (doi: 10.1111/eci.12710) (PMID:27930821)

Park, J. H. , Van Wyk, H. C., McMillan, D. C. , Quinn, J. A. , Clark, J., Roxburgh, C. , Horgan, P. G. and Edwards, J. (2017) Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host. Clinical Cancer Research, 23(7), pp. 1698-1709. (doi: 10.1158/1078-0432.CCR-16-1416) (PMID:27678454)

Van Wyk, H. , Going, J., Horgan, P. and McMillan, D. C. (2017) The role of perineural invasion in predicting survival in patients with primary operable colorectal cancer: a systematic review. Critical Reviews in Oncology/Hematology, 112, pp. 11-20. (doi: 10.1016/j.critrevonc.2017.02.005) (PMID:28325252)

Watt, D., Mcsorley, S. T. , Park, J. H. , Horgan, P. G. and McMillan, D. C. (2017) A postoperative systemic inflammation score predicts short- and long-term outcomes in patients undergoing surgery for colorectal cancer. Annals of Surgical Oncology, 24(4), pp. 1100-1109. (doi: 10.1245/s10434-016-5659-4) (PMID:27822634)

Dolan, R. , MacLeod, N. J., McSorley, S. T. , Horgan, P. G. , Laird, B. and McMillan, D. C. (2017) Evaluation of Systemic Inflammation-based Prognostic Scores in Patients With Advanced Colorectal Cancer Receiving Palliative Pelvic Radiotherapy (RT). 2017 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 19-21 Jan 2017. (doi: 10.1200/jco.2017.35.4_suppl.558)

Dolan, R. , McSorley, S. T. , McMillan, D. C. and Horgan, P. G. (2017) Association of Ongoing Systemic Inflammatory Response (SIR) at Diagnosis With Lymph Node Retrieval and Node Positivity in Patients Undergoing Surgery for Colonic Cancer. 2017 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 19-21 Jan 2017. (doi: 10.1200/jco.2017.35.4_suppl.550)

Ghashut, R. A., McMillan, D. C. , Kinsella, J. and Talwar, D. (2017) Erythrocyte concentrations of B1, B2, B6 but not plasma C and E are reliable indicators of nutrition status in the presence of systemic inflammation. Clinical Nutrition ESPEN, 17, pp. 54-62. (doi: 10.1016/j.clnesp.2016.10.007) (PMID:28361748)

Mcsorley, S. T. , Khor, B. Y., MacKJay, G. J., Horgan, P. G. and McMillan, D. C. (2017) Examination of a CRP first approach for the detection of postoperative complications in patients undergoing surgery for colorectal cancer: a pragmatic study. Medicine, 96(7), e6133. (doi: 10.1097/MD.0000000000006133) (PMID:28207541)

Khor, B. Y., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2017) The relationship between systemic inflammation and stoma formation following anterior resection for rectal cancer: a cross-sectional study. International Journal of Surgery, 37, pp. 79-84. (doi: 10.1016/j.ijsu.2016.12.010) (PMID:27940290)

Dolan, R. , McLeod, N., McSorley, S. , McMillan, D. and Horgan, P. (2017) Evaluation of Systemic Inflammation Based Prognostic Scoresin Patients with Advanced Rectal Cancer Receiving Palliative Pelvicradiotherapy. International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Glasgow, UK, 03-05 May 2017.

Dolan, R. , McSorley, S. , McMillan, D. and Horgan, P. (2017) Ongoing Systemic Inflammatory Response at Diagnosis is Notassociated with Lower Lymph Node Retrieval and Higher Node Positivityin Patients Undergoing Surgery for Colonic Cancer. International Surgical Congress of the Association of Surgeons of Great Britain and Ireland, Glasgow, UK, 03-05 May 2017.

Little, C. H., Combet, E. , McMillan, D. C. , Horgan, P. G. and Roxburgh, C. S.D. (2017) The role of dietary polyphenols in the moderation of the inflammatory response in early stage colorectal cancer. Critical Reviews in Food Science and Nutrition, 57(11), pp. 2310-2320. (doi: 10.1080/10408398.2014.997866)

McSorley, S. T. , Dolan, R. D. , Roxburgh, C. S.D. , McMillan, D. C. and Horgan, P. G. (2017) How and why systemic inflammation worsens quality of life in patients with advanced cancer. Expert Review of Quality of Life in Cancer Care, 2(3), pp. 167-175. (doi: 10.1080/23809000.2017.1331705)

2016

Gujam, F. J.A., McMillan, D. C. and Edwards, J. (2016) The relationship between total and phosphorylated STAT1 and STAT3 tumour cell expression, components of tumour microenvironment and survival in patients with invasive ductal breast cancer. Oncotarget, 7(47), pp. 77607-77621. (doi: 10.18632/oncotarget.12730) (PMID:27769057)

Mansouri, D. , McMillan, D. C. , McIlveen, E., Crighton, E. M., Morrison, D. and Horgan, P. G. (2016) A comparison of tumour and host prognostic factors in screen-detected versus non screen-detected colorectal cancer: a contemporaneous study. Colorectal Disease, 18(10), pp. 967-975. (doi: 10.1111/codi.13295) (PMID:26859503)

Mcsorley, S. T. , Jones, I., McMillan, D. C. and Talwar, D. (2016) Quantitative data on the magnitude of the systemic inflammatory response and its relationship with serum measures of iron status. Translational Research, 176, pp. 119-126. (doi: 10.1016/j.trsl.2016.05.004) (PMID:27337525)

Roseweir, A. K. , Powell, A. G.M.T., Bennett, L., Van Wyk, H. C. , Park, J. , McMillan, D. C. , Horgan, P. G. and Edwards, J. (2016) Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer. Oncotarget, 7(43), pp. 70601-70612. (doi: 10.18632/oncotarget.12134) (PMID:27661110)

McSorley, S. T. , Watt, D. G., Horgan, P. G. and McMillan, D. C. (2016) Postoperative systemic inflammatory response, complication severity, and survival following surgery for colorectal cancer. Annals of Surgical Oncology, 23(9), pp. 2832-2840. (doi: 10.1245/s10434-016-5204-5) (PMID:27016295) (PMCID:PMC4972846)

Rafferty, M.J., McMillan, D.C. , Preston, T.C. , Hamid, R., Small, A.C., Joshi, N. and Stanley, A.J. (2016) Reprioritization of liver export protein synthesis in patients with decompensated alcoholic liver disease. Journal of Hepatology and Gastrointestinal Disorders, 2(3), 1000135. (doi: 10.4172/2475-3181.1000135)

Laird, B. J.A., Fallon, M., Hjermstad, M. J., Tuck, S., Kaasa, S., Klepstad, P. and McMillan, D. C. (2016) Quality of life in patients with advanced cancer: differential association with performance status and systemic inflammatory response. Journal of Clinical Oncology, 34(23), pp. 2769-2775. (doi: 10.1200/JCO.2015.65.7742) (PMID:27354484)

van Wyk, H. C. , Park, J. H. , Edwards, J. , Horgan, P. G. , McMillan, D. C. and Going, J. J. (2016) The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer. British Journal of Cancer, 115(2), pp. 156-163. (doi: 10.1038/bjc.2016.173) (PMID:27299960)

Mansouri, D. , Powell, A., Park, J. H. , McMillan, D. C. and Horgan, P. G. (2016) Long-term follow-up of patients undergoing resection of tnm stage i colorectal cancer: an analysis of tumour and host determinants of outcome. World Journal of Surgery, 40(6), pp. 1485-1491. (doi: 10.1007/s00268-016-3443-z) (PMID:26920405)

Ghashut, R. A., McMillan, D. C. , Kinsella, J., Vasilaki, A. T. , Talwar, D. and Duncan, A. (2016) The effect of the systemic inflammatory response on plasma zinc and selenium adjusted for albumin. Clinical Nutrition, 35(2), pp. 381-387. (doi: 10.1016/j.clnu.2015.02.010) (PMID:25753552)

Palani Velu, L.K., McKay, C.J., Carter, C.R., McMillan, D.C. , Jamieson, N.B. and Dickson, E.J. (2016) Serum amylase and C-reactive protein in risk stratification of pancreas-specific complications after pancreaticoduodenectomy. British Journal of Surgery, 103(5), pp. 553-563. (doi: 10.1002/bjs.10098) (PMID:26898605)

Park, J. H. , McMillan, D. C. , Edwards, J. , Horgan, P. G. and Roxburgh, C. S.D. (2016) Comparison of the prognostic value of measures of the tumor inflammatory cell infiltrate and tumor-associated stroma in patients with primary operable colorectal cancer. OncoImmunology, 5(3), e1098801. (doi: 10.1080/2162402X.2015.1098801)

Park, J. H. , Watt, D. G., Roxburgh, C. S.D. , Horgan, P. G. and McMillan, D. C. (2016) Colorectal cancer, systemic inflammation, and outcome: staging the tumor and staging the host. Annals of Surgery, 263(2), pp. 326-336. (doi: 10.1097/SLA.0000000000001122) (PMID:25575264)

McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2016) The impact of the type and severity of postoperative complications on long-term outcomes following surgery for colorectal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 97, pp. 168-177. (doi: 10.1016/j.critrevonc.2015.08.013) (PMID:26330375)

Roxburgh, C. and McMillan, D. (2016) Therapeutics targeting innate immune/inflammatory responses through the interleukin-6/JAK/STAT signal transduction pathway in patients with cancer. Translational Research, 167(1), pp. 61-66. (doi: 10.1016/j.trsl.2015.08.013) (PMID:26432924)

McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2016) The impact of preoperative corticosteroids on the systemic inflammatory response and postoperative complications following surgery for gastrointestinal cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology, 101, pp. 139-150. (doi: 10.1016/j.critrevonc.2016.03.011) (PMID:26997303)

Park, J. H. , Powell, A. G., Roxburgh, C. S.D. , Horgan, P. G. , McMillan, D. c. and Edwards, J. (2016) Mismatch repair status in patients with primary operable colorectal cancer: associations with the local and systemic tumour environment. British Journal of Cancer, 114, pp. 562-570. (doi: 10.1038/bjc.2016.17) (PMID:26859693)

2015

Palani Velu, L., Chandrabalan, V., McMillan, D. , McKay, C., Carter, C. R., Jamieson, N. and Dickson, E. (2015) Routine drainage after pancreaticoduodenectomy. Annals of Surgery, 262(6), e107. (doi: 10.1097/sla.0000000000000758) (PMID:24887980)

VAN Wyk, H. C., Foulis, A., Roxburgh, C. , Orange, C., Horgan, P. and McMillan, D. (2015) Comparison of methods to identify lymphatic and blood vessel invasion and their prognostic value in patients with primary operable colorectal cancer. Anticancer Research, 35(12), pp. 6457-6463. (PMID:26637856)

Gujam, F.J.A., McMillan, D.C. , Mohammed, Z.M.A., Edwards, J. and Going, J.J. (2015) The relationship between tumour budding, the tumour microenvironment and survival in patients with invasive ductal breast cancer. British Journal of Cancer, 113(7), pp. 1066-1074. (doi: 10.1038/bjc.2015.287) (PMID:26263482)

Palani Velu, L. K., Steele, C. W. , Dickson, E., Carter, C. R., McKay, C. J., Horgan, P. G. , McMillan, D. C. and Jamieson, N. B. (2015) RE:nab-paclitaxel plus gemcitabine for metastatic pancreatic cancer: long-term survival from a phase III trial. Journal of the National Cancer Institute, 107(9), djv204. (doi: 10.1093/jnci/djv204) (PMID:26251329)

Watt, D. G., McSorley, S. T. , Horgan, P. G. and McMillan, D. C. (2015) Enhanced recovery after surgery. Medicine, 94(36), e1286. (doi: 10.1097/md.0000000000001286) (PMCID:PMC4616657)

Conway, F.J.S., Talwar, D. and McMillan, D.C. (2015) The relationship between acute changes in the systemic inflammatory response and plasma ascorbic acid, alpha-tocopherol and lipid peroxidation after elective hip arthroplasty. Clinical Nutrition, 34(4), pp. 642-646. (doi: 10.1016/j.clnu.2014.07.004) (PMID:25048713)

Mansouri, D. , McMillan, D.C. , Crearie, C., Morrison, D.S., Crighton, E.M. and Horgan, P.G. (2015) Temporal trends in mode, site and stage of presentation with the introduction of colorectal cancer screening: a decade of experience from the West of Scotland. British Journal of Cancer, 113, pp. 556-561. (doi: 10.1038/bjc.2015.230) (PMID:26158422)

McSorley, S. T. , Ramanathan, M., Horgan, P. and McMillan, D. (2015) Postoperative C-reactive protein measurement predicts the severity of complications following surgery for colorectal cancer. International Journal of Colorectal Disease, 30(7), pp. 913-917. (doi: 10.1007/s00384-015-2229-3) (PMID:25922147)

Watt, D. G., Martin, J. C., Park, J. H. , Horgan, P. G. and McMillan, D. C. (2015) Neutrophil count is the most important prognostic component of the differential white cell count in patients undergoing elective surgery for colorectal cancer. American Journal of Surgery, 210(1), pp. 24-30. (doi: 10.1016/j.amjsurg.2014.12.031) (PMID:25842358)

Simmons, C. P., Koinis, F., Fallon, M. T., Fearon, K. C., Bowden, J., Solheim, T. S., Gronberg, B. H., McMillan, D. C. , Gioulbasanis, I. and Laird, B. J. (2015) Prognosis in advanced lung cancer – a prospective study examining key clinicopathological factors. Lung Cancer, 88(3), pp. 304-309. (doi: 10.1016/j.lungcan.2015.03.020) (PMID:25870155)

McGowan, S., Jones, J., McMillan, D. , McLaughlin, K., Smith, S., Leyland, K., Charleton, P. and Donaldson, M. (2015) Screening for hypothyroidism in Down syndrome using the capillary thyroid stimulating hormone method. Journal of Pediatrics, 166(4), 1013-1017.e2. (doi: 10.1016/j.jpeds.2014.12.035) (PMID:25648292)

McSorley, S. T. , Ramanathan, M. L., Horgan, P. G. and McMillan, D. C. (2015) Mo1619 Postoperative C-reactive protein measurement predicts the severity of complications following surgery for colorectal cancer. Gastroenterology, 148(4), S-1152. (doi: 10.1016/S0016-5085(15)33932-9)

McSorley, S. T. , Watt, D. G., Horgan, P. G. and McMillan, D. C. (2015) 868 Complication type and severity have an adverse effect on long-term oncological outcome following surgery for colorectal cancer. Gastroenterology, 148(4), S-1122. (doi: 10.1016/S0016-5085(15)33823-3)

Watt, D. G., Horgan, P. G. and McMillan, D. C. (2015) Comment on 'prognostic performance of inflammation-based prognostic indices in patients with resectable colorectal liver metastases'. Medical Oncology, 32(5), (doi: 10.1007/s12032-015-0617-8) (PMID:25904501)

Watt, D. G., McSorley, S. T. , Park, J. H. , Horgan, P. G. and McMillan, D. C. (2015) 879 The validation of C-reactive protein and albumin as predictors of post-operative infective complications and their clinical utility in patients with colorectal cancer. Gastroenterology, 148(4), S-1125. (doi: 10.1016/S0016-5085(15)33834-8)

Watt, D. G., Park, J. H. , Ramanathan, M. L., Horgan, P. G. and McMillan, D. C. (2015) Tu1760 neutrophil count, but not other components of a white cell count, reflects the impact of the systemic inflammatory response and long term survival in patients following elective surgery for colorectal cancer. Gastroenterology, 148(4), S-1175. (doi: 10.1016/S0016-5085(15)34008-7)

Ramanathan, M. L., Mackay, G., Platt, J., Horgan, P. G. and McMillan, D. C. (2015) The impact of open versus laparoscopic resection for colon cancer on C-reactive protein concentrations as a predictor of postoperative infective complications. Annals of Surgical Oncology, 22(3), pp. 938-943. (doi: 10.1245/s10434-014-4065-z) (PMID:25201503)

Farhan-Alanie, O.M., McMahon, J. and McMillan, D.C. (2015) Systemic inflammatory response and survival in patients undergoing curative resection of oral squamous cell carcinoma. British Journal of Oral and Maxillofacial Surgery, 53(2), pp. 126-131. (doi: 10.1016/j.bjoms.2014.10.007) (PMID:25440150)

Grose, D. et al. (2015) The impact of comorbidity upon determinants of outcome in patients with lung cancer. Lung Cancer, 87(2), pp. 186-192. (doi: 10.1016/j.lungcan.2014.11.012)

Park, J. H. , McMillan, D. C. , Powell, A. G., Richards, C. H., Horgan, P. G. , Edwards, J. and Roxburgh, C. S.D. (2015) Evaluation of a tumor microenvironment-based prognostic score in primary operable colorectal cancer. Clinical Cancer Research, 21(4), pp. 882-888. (doi: 10.1158/1078-0432.CCR-14-1686) (PMID:25473000)

van Wyk, H.C. , Park, J. , Roxburgh, C. , Horgan, P. , Foulis, A. and McMillan, D. C. (2015) The role of tumour budding in predicting survival in patients with primary operable colorectal cancer: a systematic review. Cancer Treatment Reviews, 41(2), pp. 151-159. (doi: 10.1016/j.ctrv.2014.12.007) (PMID:25549950)

Watt, D. G., Horgan, P. G. and McMillan, D. C. (2015) Routine clinical markers of the magnitude of the systemic inflammatory response after elective operation: a systematic review. Surgery, 157(2), pp. 362-380. (doi: 10.1016/j.surg.2014.09.009) (PMID:25616950)

Conway, F. J.S. and McMillan, D. C. (2015) Plasma vitamin D concentration and survival in colorectal cancer: potential confounding by the systemic inflammatory response. Journal of Clinical Oncology, 33(2), p. 224. (doi: 10.1200/JCO.2014.59.2386) (PMID:25488961)

Grivennikov, S., Watt, D. G., Proctor, M. J., Park, J. H. , Horgan, P. G. and McMillan, D. C. (2015) The Neutrophil-Platelet Score (NPS) predicts survival in primary operable colorectal cancer and a variety of common cancers. PLoS ONE, 10(11), e0142159. (doi: 10.1371/journal.pone.0142159) (PMID:26544968) (PMCID:PMC4636235)

Mansouri, D. , Park, J.H. , Orange, C., Crighton, E.M., Horgan, P.G. and McMillan, D.C. (2015) Changes in the Inflammatory Microenvironment in Premalignant Colonic Adenomatous Polyps: Evidence for Immunosurveillance? Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 535. (doi: 10.1200/jco.2015.33.3_suppl.535)

Park, J.H. , Mansouri, D. , Orange, C., Horgan, P.G. and McMillan, D.C. (2015) Assessment of the Tumor Inflammatory Cell Infiltrate in Preoperative Colonoscopic Biopsies of Patients with Primary Operable Colorectal Cancer. Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 637. (doi: 10.1200/jco.2015.33.3_suppl.637)

Park, J.H. , McMillan, D.C. , Horgan, P.G. and Roxburgh, C.S.D. (2015) The Clinical Utility of a Tumour Microenvironment-based Histopathological Score in Patients with Primary Operable Colorectal Cancer. Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 664. (doi: 10.1200/jco.2015.33.3_suppl.664)

Proctor, M., McMillan, D. C. , Horgan, P. G. , Fletcher, C. D., Talwar, D. and Morrison, D. S. (2015) Systemic inflammation predicts all-cause mortality: a Glasgow Inflammation Outcome Study. PLoS ONE, 10(3), e0116206. (doi: 10.1371/journal.pone.0116206) (PMID:25730322) (PMCID:PMC4346265)

Watt, D.G., Park, J.H. , Horgan, P.G. and McMillan, D.C. (2015) The Relationship Between Red Cell Distribution Width (RDW), Markers of Systemic Inflammation and Survival in Patients Undergoing Curative Surgery for Colorectal Cancer. Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 589. (doi: 10.1200/jco.2015.33.3_suppl.589)

Watt, D.G., Park, J.H. , Ramanathan, M.L., Horgan, P.G. and McMillan, D.C. (2015) Pre-and Postoperative Inflammatory Response to Predict Survival in Patients Undergoing Potentially Curative Resection for Colorectal Cancer. Journal of Clinical Oncology 33(3_suppl). 2015 Gastrointestinal Cancers Symposium, San Francisco, CA, USA, 15-17 Jan 2015. p. 609. (doi: 10.1200/jco.2015.33.3_suppl.609)

Watt, D., Roxburgh, C. , White, M., Chan, J., Horgan, P. and McMillan, D. (2015) A survey of attitudes towards the clinical application of systemic inflammation based prognostic scores in cancer. Mediators of Inflammation, 2015, 842070. (doi: 10.1155/2015/842070) (PMID:26504363) (PMCID:PMC4609481)

2014

Park, J.H. , Roxburgh, C.S.D. and McMillan, D.C. (2014) Comment on ‘Tumour-infiltrating inflammation and prognosis in colorectal cancer: systematic review and meta-analysis’. British Journal of Cancer, 111(12), p. 2372. (doi: 10.1038/bjc.2014.296)

Diakos, C. I., Charles, K. A., McMillan, D. C. and Clarke, S. J. (2014) Cancer-related inflammation and treatment effectiveness. Lancet Oncology, 15(11), e493-e503. (doi: 10.1016/S1470-2045(14)70263-3)

Oliphant, R., Nicholson, G. A., Horgan, P. G. , McMillan, D. C. and Morrison, D. S. (2014) The impact of surgical specialisation on survival following elective colon cancer surgery. International Journal of Colorectal Disease, 29(9), pp. 1143-1150. (doi: 10.1007/s00384-014-1965-0) (PMID:25034593)

Douglas, E. and McMillan, D. C. (2014) Towards a simple objective framework for the investigation and treatment of cancer cachexia: The Glasgow Prognostic Score. Cancer Treatment Reviews, 40(6), pp. 685-691. (doi: 10.1016/j.ctrv.2013.11.007)

Palani Velu, L. K., Chandrabalan, V. V., Jabbar, S., McMillan, D. C. , McKay, C. J., Carter, C. R., Jamieson, N. B. and Dickson, E. J. (2014) Serum amylase on the night of surgery predicts clinically significant pancreatic fistula after pancreaticoduodenectomy. HPB, 16(7), pp. 610-619. (doi: 10.1111/hpb.12184) (PMID:24246024)

Ferrari, N., Mohammed, Z. M. A., Nixon, C., Mason, S. M., Mallon, E., McMillan, D. C. , Morris, J. S. , Cameron, E. R. , Edwards, J. and Blyth, K. (2014) Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer. PLoS ONE, 9(6), e100759. (doi: 10.1371/journal.pone.0100759) (PMID:24967588) (PMCID:PMC4072705)

Grose, D. et al. (2014) Comorbidities in lung cancer: prevalence, severity and links with socioeconomics status and treatment. Postgraduate Medical Journal, 90(1064), pp. 305-310. (doi: 10.1136/postgradmedj-2013-132186)

Roxburgh, C. S. D. , McMillan, D. C. , Richards, C. H., Atwan, M., Anderson, J., Harvey, T., Horgan, P. G. and Foulis, A. K. (2014) The clinical utility of the combination of T stage and venous invasion to predict survival in patients undergoing surgery for colorectal cancer. Annals of Surgery, 259(6), pp. 1156-1165. (doi: 10.1097/SLA.0000000000000229)

Oliphant, R., Mansouri, D. , Nicholson, G. A., McMillan, D. C. , Horgan, P. G. and Morrison, D. S. (2014) Emergency presentation of node-negative colorectal cancer treated with curative surgery is associated with poorer short and longer-term survival. International Journal of Colorectal Disease, 29(5), pp. 591-598. (doi: 10.1007/s00384-014-1847-5) (PMID:24651957)

van Wyk, H. C. , Roxburgh, C. S. , Horgan, P. G. , Foulis, A. F. and McMillan, D. C. (2014) The detection and role of lymphatic and blood vessel invasion in predicting survival in patients with node negative operable primary colorectal cancer. Critical Reviews in Oncology/Hematology, 90(1), pp. 77-90. (doi: 10.1016/j.critrevonc.2013.11.004) (PMID:24332522)

Forrester, R., Guthrie, G.J.K., Orange, C., Horgan, P.G. , McMillan, D.C. and Roxburgh, C.S.D. (2014) Comparison of visual and automated assessment of tumour inflammatory infiltrates in patients with colorectal cancer. European Journal of Cancer, 50(3), pp. 544-552. (doi: 10.1016/j.ejca.2013.11.003) (PMID:24332571)

Gujam, F.J.A., Going, J.J., Edwards, J. , Mohammed, Z.M.A. and McMillan, D.C. (2014) The role of lymphatic and blood vessel invasion in predicting survival and methods of detection in patients with primary operable breast cancer. Critical Reviews in Oncology/Hematology, 89(2), pp. 231-241. (doi: 10.1016/j.critrevonc.2013.08.014)

Park, J.H. , McMillan, D.C. , Horgan, P.G. and Roxburgh, C.S. (2014) The impact of anti-inflammatory agents on the outcome of patients with colorectal cancer. Cancer Treatment Reviews, 40(1), pp. 68-77. (doi: 10.1016/j.ctrv.2013.05.006)

Stefanowicz, F., Gashut, R. A., Talwar, D., Duncan, A., Beulshausen, J. F., McMillan, D. C. and Kinsella, J. (2014) Assessment of plasma and red cell trace element concentrations, disease severity, and outcome in patients with critical illness. Journal of Critical Care, 29(2), pp. 214-218. (doi: 10.1016/j.jcrc.2013.10.012)

McGlynn, L.M. et al. (2014) SIRT2: Tumour suppressor or tumour promoter in operable breast cancer? European Journal of Cancer, 50(2), pp. 290-301. (doi: 10.1016/j.ejca.2013.10.005) (PMID:24183459)

Ghashut, R. A., Talwar, D., Kinsella, J., Duncan, A. and McMillan, D. C. (2014) The effect of the systemic inflammatory response on plasma vitamin 25 (OH) D concentrations adjusted for albumin. PLoS ONE, 9(3), e92614. (doi: 10.1371/journal.pone.0092614) (PMID:24667823) (PMCID:PMC3965436)

Gujam, F.J.A., Edwards, J. , Mohammed, Z.M.A., Going, J.J. and McMillan, D.C. (2014) The relationship between the tumour stroma percentage, clinicopathological characteristics and outcome in patients with operable ductal breast cancer. British Journal of Cancer, 111(1), pp. 157-165. (doi: 10.1038/bjc.2014.279)

Gujam, F. J.A., Going, J. J., Mohammed, Z. M.A., Orange, C., Edwards, J. and McMillan, D. C. (2014) Immunohistochemical detection improves the prognostic value of lymphatic and blood vessel invasion in primary ductal breast cancer. BMC Cancer, 14(1), p. 676. (doi: 10.1186/1471-2407-14-676)

Oliphant, R., Horgan, P. G. , Morrison, D. S. and McMillan, D. C. (2014) Validation of a modified clinical risk score to predict cancer-specific survival for stage II colon cancer. Cancer Medicine, (doi: 10.1002/cam4.352)

Park, J.H. , Richards, C.H., McMillan, D.C. , Horgan, P.G. and Roxburgh, C.S.D. (2014) The relationship between tumour stroma percentage, the tumour microenvironment and survival in patients with primary operable colorectal cancer. Annals of Oncology, 25(3), pp. 644-651. (doi: 10.1093/annonc/mdt593)

Richards, C. H., Roxburgh, C. S.D. , Powell, A. G., Foulis, A. K., Horgan, P. G. and McMillan, D. C. (2014) The clinical utility of the local inflammatory response in colorectal cancer. European Journal of Cancer, 50(2), pp. 309-319. (doi: 10.1016/j.ejca.2013.09.008) (PMID:24103145)

Roxburgh, C.S.D. and McMillan, D.C. (2014) Cancer and systemic inflammation: treat the tumour and treat the host. British Journal of Cancer, 110(6), pp. 1409-1412. (doi: 10.1038/bjc.2014.90)

2013

Powell, A.G.M.T., Ferguson, J., Al-Mulla, F., Orange, C., McMillan, D.C. , Horgan, P.G. , Edwards, J. and Going, J.J. (2013) The relationship between genetic profiling, clinicopathological factors and survival in patients undergoing surgery for node-negative colorectal cancer: 10-year follow-up. Journal of Cancer Research and Clinical Oncology, 139(12), pp. 2013-2020. (doi: 10.1007/s00432-013-1521-2)

Chandrabalan, V.V., McMillan, D.C. , Carter, R., Kinsella, J., McKay, C.J., Carter, C.R. and Dickson, E.J. (2013) Pre-operative cardiopulmonary exercise testing predicts adverse post-operative events and non-progression to adjuvant therapy after major pancreatic surgery. HPB, 15(11), pp. 899-907. (doi: 10.1111/hpb.12060)

Mansouri, D. , McMillan, D.C. , Roxburgh, C.S.D. , Moug, S.J., Crighton, E.M. and Horgan, P.G. (2013) Flexible sigmoidoscopy following a positive faecal occult blood test within a bowel screening programme may reduce the detection of neoplasia. Colorectal Disease, 15(11), pp. 1375-1381. (doi: 10.1111/codi.12377)

Ramanathan, M.L., MacKay, G., Platt, J., Horgan, P.G. and McMillan, D.C. (2013) Impact of day 2 C-reactive protein on day 3 and 4 thresholds associated with infective complications following curative surgery for colorectal cancer. World Journal of Surgery, 37(11), pp. 2705-2710. (doi: 10.1007/s00268-013-2177-4)

Ghashut, R. A., McMillan, D. C. , Kinsella, J., Duncan, A. and Talwar, D. (2013) Quantitative data on the magnitude of the systemic inflammatory response and its effect on carotenoids status based on plasma measurements. e-SPEN Journal, 8(5), e193-e199. (doi: 10.1016/j.clnme.2013.07.006)

Guthrie, G.J.K., Charles, K.A., Roxburgh, C.S.D. , Horgan, P.G. , McMillan, D.C. and Clarke, S.J. (2013) The systemic inflammation-based neutrophil–lymphocyte ratio: experience in patients with cancer. Critical Reviews in Oncology/Hematology, 88(1), pp. 218-230. (doi: 10.1016/j.critrevonc.2013.03.010)

McMillan, D.C. and Horgan, P.G. (2013) Preoperative indicators of the systemic inflammatory response in the treatment of patients with gastrointestinal cancer. British Journal of Surgery, 100(10), pp. 1260-1.

Oliphant, R., Nicholson, G.A., Horgan, P. , Molloy, R.G., McMillan, D. and Morrison, D. (2013) Contribution of surgical specialization to improved colorectal cancer survival. British Journal of Surgery, 100(10), pp. 1388-1395. (doi: 10.1002/bjs.9227)

Mansouri, D. , McMillan, D.C. , Crighton, E.M. and Horgan, P.G. (2013) Comment on Luoet et al.: diabetes mellitus and the incidence and mortality of colorectal cancer: a meta-analysis of 24 cohort studies. Colorectal Disease, 15(8), p. 1045. (doi: 10.1111/codi.12280)

McMillan, D.C. (2013) The systemic inflammation-based Glasgow prognostic score: a decade of experience in patients with cancer. Cancer Treatment Reviews, 39(5), pp. 534-540. (doi: 10.1016/j.ctrv.2012.08.003)

Mohammed, Z.M.A., Orange, C., McMillan, D.C. , Mallon, E., Doughty, J.C., Edwards, J. and Going, J.J. (2013) Comparison of visual and automated assessment of microvessel density and their impact on outcome in primary operable invasive ductal breast cancer. Human Pathology, 44(8), pp. 1688-1695. (doi: 10.1016/j.humpath.2012.11.023)

Marla, S., McMillan, D.C. and Stallard, S. (2013) Factors influencing postoperative length of hospital stay after breast cancer surgery. Breast, 22(3), pp. 289-294. (doi: 10.1016/j.breast.2012.07.009)

Proctor, M.J., Horgan, P.G. , Talwar, D., Fletcher, C.D., Morrison, D.S. and McMillan, D.C. (2013) Optimization of the systemic inflammation-based Glasgow prognostic score. Cancer, 119(12), pp. 2325-2332. (doi: 10.1002/cncr.28018)

Mansouri, D. , McMillan, D.C. , Crighton, E. and Horgan, P.G. (2013) Screening for colorectal cancer: what is the impact on the determinants of outcome? Critical Reviews in Oncology/Hematology, 85(3), pp. 342-349. (doi: 10.1016/j.critrevonc.2012.08.006)

McMillan, D.C. (2013) Inflammatory prognostic markers in clear cell renal cell carcinoma - preoperative C-reactive protein does not improve predictive accuracy. BJU International, 111(3), E19-E20. (doi: 10.1111/bju.12020_12)

Guthrie, G.J.K., Roxburgh, C.S.D. , Horgan, P.G. and McMillan, D.C. (2013) Does interleukin-6 link explain the link between tumour necrosis, local and systemic inflammatory responses and outcome in patients with colorectal cancer? Cancer Treatment Reviews, 39(1), pp. 89-96. (doi: 10.1016/j.ctrv.2012.07.003)

Guthrie, G. and McMillan, D.C. (2013) Comment on ‘Stage-dependent alterations of the serum cytokine pattern in colorectal carcinoma’. British Journal of Cancer, 108(9), pp. 1915-1916. (doi: 10.1038/bjc.2013.161)

Guthrie, G.J.K., Roxburgh, C.S.D. , Farhan-Alanie, O.M., Horgan, P.G. and McMillan, D.C. (2013) Comparison of the prognostic value of longitudinal measurements of systemic inflammation in patients undergoing curative resection of colorectal cancer. British Journal of Cancer, 109(1), pp. 24-28. (doi: 10.1038/bjc.2013.330)

Guthrie, G.J.K., Roxburgh, C.S.D. , Richards, C.H., Horgan, P.G. and McMillan, D.C. (2013) Circulating IL-6 concentrations link tumour necrosis and systemic and local inflammatory responses in patients undergoing resection for colorectal cancer. British Journal of Cancer, 109(1), pp. 131-137. (doi: 10.1038/bjc.2013.291)

Mansouri, D. , McMillan, D.C. , Grant, Y., Crighton, E.M. and Horgan, P.G. (2013) The impact of age, sex and socioeconomic deprivation on outcomes in a colorectal cancer screening programme. PLoS ONE, 8(6), e66063. (doi: 10.1371/journal.pone.0066063) (PMID:23776606) (PMCID:PMC3680425)

Mansouri, D. , McMillan, D.C. , Roxburgh, C.S.D. , Crighton, E.M. and Horgan, P.G. (2013) The impact of aspirin, statins and ACE-inhibitors on the presentation of colorectal neoplasia in a colorectal cancer screening programme. British Journal of Cancer, 109(1), pp. 249-256. (doi: 10.1038/bjc.2013.292)

McMillan, D.C. (2013) Cancer and systemic inflammation: stage the tumour and stage the host. British Journal of Cancer, 109, p. 529. (doi: 10.1038/bjc.2013.418)

Oliphant, R., Nicholson, G. A., Horgan, P. G. , Molloy, R. G., McMillan, D. C. and Morrison, D. S. (2013) Deprivation and colorectal cancer surgery: longer-term survival inequalities are due to differential postoperative mortality between socioeconomic groups. Annals of Surgical Oncology, 20(7), pp. 2132-2139. (doi: 10.1245/s10434-013-2959-9)

Ramanathan, M.L., Roxburgh, C.S.D. , Guthrie, G.J.K., Orange, C., Talwar, D., Horgan, P.G. and McMillan, D.C. (2013) Is Perioperative systemic inflammation the result of insufficient cortisol production in patients with colorectal cancer? Annals of Surgical Oncology, 20(7), pp. 2172-2179. (doi: 10.1245/s10434-013-2943-4)

Roxburgh, C.S. , Richards, C.H., MacDonald, A.I., Powell, A.G., McGlynn, L.M., McMillan, D.C. , Horgan, P.G. , Edwards, J. and Shiels, P.G. (2013) The in situ local immune response, tumour senescence and proliferation in colorectal cancer. British Journal of Cancer, 109(8), pp. 2207-2216. (doi: 10.1038/bjc.2013.556)

Shafique, K., Proctor, M.J., McMillan, D.C. , Leung, H. , Smith, K., Sloan, B. and Morrison, D.S. (2013) The modified Glasgow prognostic score in prostate cancer: results from a retrospective clinical series of 744 patients. BMC Cancer, 13(292), (doi: 10.1186/1471-2407-13-292)

2012

Mohammed, Z.M.A., Going, J.J., Edwards, J. and McMillan, D.C. (2012) The role of the tumour inflammatory cell infiltrate in predicting recurrence and survival in patients with primary operable breast cancer. Cancer Treatment Reviews, 38(8), pp. 943-955. (doi: 10.1016/j.ctrv.2012.04.011)

Jamieson, N.B. , Mohamed, M., Oien, K.A. , Foulis, A.K., Dickson, E.J., Imrie, C.W., Carter, C.R., McKay, C.J. and McMillan, D.C. (2012) The relationship between tumor inflammatory cell infiltrate and outcome in patients with pancreatic ductal adenocarcinoma. Annals of Surgical Oncology, 19(11), pp. 3581-3590. (doi: 10.1245/s10434-012-2370-y)

Mohammed, Z.M.A., Going, J.J., McMillan, D.C. , Orange, C., Mallon, E., Doughty, J.C. and Edwards, J. (2012) Comparison of visual and automated assessment of HER2 status and their impact on outcome in primary operable invasive ductal breast cancer. Histopathology, 61(4), pp. 675-684. (doi: 10.1111/j.1365-2559.2012.04280.x)

Duncan, A., Talwar, D., McMillan, D.C. and Kinsella, J. (2012) Trace elements, the systemic inflammatory response and outcome in critical illness. Clinical Nutrition Supplements, 7(1), p. 36. (doi: 10.1016/S1744-1161(12)70080-7)

Proctor, M.J., McMillan, D.C. , Morrison, D.S., Fletcher, C.D., Horgan, P.G. and Clarke, S.J. (2012) A derived neutrophil to lymphoctye ratio predicts survival in patients with cancer. British Journal of Cancer, 107(4), pp. 695-699. (doi: 10.1038/bjc.2012.292)

Mohammed, Z.M.A., Edwards, J. , Orange, C., Mallon, E., Doughty, J., McMillan, D.C. and Going, J.J. (2012) Breast cancer outcomes by steroid hormone receptor status assessed visually and by computer image analysis. Histopathology, 61(2), pp. 283-292. (doi: 10.1111/j.1365-2559.2012.04244.x)

Partridge, M., Fallon, M., Bray, C., McMillan, D. , Brown, D. and Laird, B. (2012) Prognostication in advanced cancer: a study examining an inflammation-based score. Journal of Pain and Symptom Management, 44(2), pp. 161-167. (doi: 10.1016/j.jpainsymman.2011.08.013)

Roxburgh, C.S.D. and McMillan, D.C. (2012) The role of the in situ local inflammatory response in predicting recurrence and survival in patients with primary operable colorectal cancer. Cancer Treatment Reviews, 38(5), pp. 451-466. (doi: 10.1016/j.ctrv.2011.09.001)

Shelley, B. G., Quasim, T. , Kinsella, J., Talwar, D. and McMillan, D. C. (2012) Low-serum 25-hydroxyvitamin D reflects severity of illness in critically ill patients. Critical Care Medicine, 40(8), p. 2530. (doi: 10.1097/CCM.0b013e3182536a98) (PMID:22809939)

Leung, E. Y.L. , Roxburgh, C. S. , Talwar, D., O'Reilly, D. S., McKee, R. F., Horgan, P. G. and McMillan, D. C. (2012) The relationships between plasma and red cell vitamin B2 and B6 concentrations and the systemic and local inflammatory responses in patients with colorectal cancer. Nutrition and Cancer, 64(4), pp. 515-520. (doi: 10.1080/01635581.2012.661512) (PMID:22439733)

Leung, E. Y.L. , Scott, H. R. and McMillan, D. C. (2012) Clinical utility of the pretreatment glasgow prognostic score in patients with advanced inoperable non-small cell lung cancer. Journal of Thoracic Oncology, 7(4), pp. 655-662. (doi: 10.1097/JTO.0b013e318244ffe1) (PMID:22425914)

Richards, C.H., Roxburgh, C.S.D. , Anderson, J.H., McKee, R.F., Foulis, A.K., Horgan, P.G. and McMillan, D.C. (2012) Prognostic value of tumour necrosis and host inflammatory responses in colorectal cancer. British Journal of Surgery, 99(2), pp. 287-294. (doi: 10.1002/bjs.7755)

Duncan, A., Talwar, D., McMillan, D.C. , Stefanowicz, F. and O'Reilly, D.O.J. (2012) Quantitative data on the magnitude of the systemic inflammatory response and its effect on micronutrient status based on plasma measurements. American Journal of Clinical Nutrition, 95(1), pp. 64-71. (doi: 10.3945/ajcn.111.023812)

Dutta, S., Going, J.J., Crumley, A.B.C., Mohammed, Z., Orange, C., Edwards, J. , Fullarton, G.M., Horgan, P.G. and McMillan, D.C. (2012) The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma. British Journal of Cancer, 106(4), pp. 702-710. (doi: 10.1038/bjc.2011.610)

Mohammed, Z.M.A., Going, J.J., Edwards, J. , Elsberger, B., Doughty, J.C. and McMillan, D.C. (2012) The relationship between components of tumour inflammatory cell infiltrate and clinicopathological factors and survival in patients with primary operable invasive ductal breast cancer. British Journal of Cancer, 107(5), pp. 864-873. (doi: 10.1038/bjc.2012.347)

Mohammed, Z.M.A., McMillan, D.C. , Elsberger, B., Going, J.J., Orange, C., Mallon, E., Doughty, J.C. and Edwards, J. (2012) Comparison of visual and automated assessment of Ki-67 proliferative activity and their impact on outcome in primary operable invasive ductal breast cancer. British Journal of Cancer, 106(2), pp. 383-388. (doi: 10.1038/bjc.2011.569)

Platt, J.J., Ramanathan, M.L., Crosbie, R.A., Anderson, J.H., McKee, R.F., Horgan, P.G. and McMillan, D.C. (2012) C-reactive protein as a predictor of postoperative infective complications after curative resection in patients with colorectal cancer. Annals of Surgical Oncology, 19(13), pp. 4168-4177. (doi: 10.1245/s10434-012-2498-9)

Richards, C.H., Flegg, K.M., Roxburgh, C.S.D. , Going, J.J., Mohammed, Z., Horgan, P.G. and McMillan, D.C. (2012) The relationships between cellular components of the peritumoural inflammatory response, clinicopathological characteristics and survival in patients with primary operable colorectal cancer. British Journal of Cancer, 106(12), pp. 2010-2015. (doi: 10.1038/bjc.2012.211)

Roxburgh, C.S.D. , Richards, C.H., Moug, S.J., Foulis, A.K., McMillan, D.C. and Horgan, P.G. (2012) Determinants of short- and long-term outcome in patients undergoing simultaneous resection of colorectal cancer and synchronous colorectal liver metastases. International Journal of Colorectal Disease, 27(3), pp. 363-369. (doi: 10.1007/s00384-011-1339-9)

Shafique, K., Proctor, M.J., McMillan, D.C. , Qureshi, K., Leung, H. and Morrison, D.S. (2012) Systemic inflammation and survival of patients with prostate cancer: evidence from the Glasgow Inflammation Outcome Study. Prostate Cancer and Prostatic Diseases, 15(2), pp. 195-201. (doi: 10.1038/pcan.2011.60)

2011

Proctor, M.J., Morrison, D.S., Talwar, D., Balmer, S.M., Fletcher, C.D., O’Reilly, D.S.J., Foulis, A.K., Horgan, P.G. and McMillan, D.C. (2011) A comparison of inflammation-based prognostic scores in patients with cancer. A Glasgow Inflammation Outcome Study. European Journal of Cancer, 47(17), pp. 2633-2641. (doi: 10.1016/j.ejca.2011.03.028)

Maxwell, F., McGlynn, L.M., Muir, H.C., Talwar, D., Benzeval, M., Robertson, T., Roxburgh, C.S., McMillan, D. , Horgan, P.G. and Shiels, P. (2011) Telomere attrition and decreased Fetuin A levels indicate accelerated biological ageing and are implicated in the pathogenesis of colorectal cancer. Clinical Cancer Research, 17(17), pp. 5573-5581. (doi: 10.1158/1078-0432.CCR-10-3271)

Clarke, S.J., Chua, W., Moore, M., Kao, S., Phan, V., Tan, C., Charles, K. and McMillan, D.C. (2011) Use of inflammatory markers to guide cancer treatment. Clinical Pharmacology and Therapeutics, 90(3), pp. 475-478. (doi: 10.1038/clpt.2011.122)

Crumley, A.B.C., Going, J.J., Hilmy, M., Dutta, S., Tannahill, C., McKernan, M., Edwards, J. , Stuart, R.C. and McMillan, D.C. (2011) Interrelationships between tumor proliferative activity, leucocyte and macrophage infiltration, systemic inflammatory response, and survival in patients selected for potentially curative resection for gastroesophageal cancer. Annals of Surgical Oncology, 18(9), pp. 2604-2612. (doi: 10.1245/s10434-011-1658-7)

Dutta, S., Crumley, A.B.C., Fullarton, G.M., Horgan, P. and McMillan, D. (2011) Comparison of the prognostic value of tumour- and patient-related factors in patients undergoing potentially curative resection of oesophageal cancer. World Journal of Surgery, 35(8), pp. 1861-1866. (doi: 10.1007/s00268-011-1130-7)

Talwar, D., O'Reilly, D.S.J. and McMillan, D.C. (2011) Serum 25-hydroxyvitamin D is a reliable indicator of vitamin D status - Reply. American Journal of Clinical Nutrition, 94(2), p. 620. (doi: 10.3945/ajcn.111.019679)

Roxburgh, C., McDonald, A., Salmond, J., Oien, K. , Anderson, J., McKee, R., Horgan, P. and McMillan, D. (2011) Adjuvant chemotherapy for resected colon cancer: comparison of the prognostic value of tumour and patient related factors. International Journal of Colorectal Disease, 26(4), pp. 483-492. (doi: 10.1007/s00384-010-1120-5)

Roxburgh, C.S.D., Platt, J.J., Leitch, E.F., Kinsella, J., Horgan, P.G. and McMillan, D.C. (2011) Relationship between preoperative comorbidity, systemic inflammatory response, and survival in patients undergoing curative resection for colorectal cancer. Annals of Surgical Oncology, 18(4), pp. 997-1005. (doi: 10.1245/s10434-010-1410-8)

Dutta, S., Al-Mrabt, N.M., Fullarton, G.M., Horgan, P.G. and McMillan, D.C. (2011) A comparison of POSSUM and GPS models in the prediction of post-operative outcome in patients undergoing oesophago-gastric cancer resection. Annals of Surgical Oncology, 18(10), pp. 2808-2817. (doi: 10.1245/s10434-011-1676-5)

Dutta, S., Fullarton, G.M., Forshaw, M.J., Horgan, P.G. and McMillan, D.C. (2011) Persistent Elevation of C-Reactive Protein Following Esophagogastric Cancer Resection as a Predictor of Postoperative Surgical Site Infectious Complications. World Journal of Surgery, 35(5), pp. 1017-1025. (doi: 10.1007/s00268-011-1002-1)

Elsberger, B., Lankston, L., McMillan, D.C. , Underwood, M.A. and Edwards, J. (2011) Presence of tumoural C-reactive protein correlates with progressive prostate cancer. Prostate Cancer and Prostatic Diseases, 14(2), pp. 122-128. (doi: 10.1038/pcan.2011.5)

Jamieson, N.B., Denley, S.M., Logue, J., MacKenzie, D.J., Foulis, A.K., Dickson, E.J., Imrie, C.W., Carter, R., McKay, C.J. and McMillan, D.J. (2011) A prospective comparison of the prognostic value of tumor- and patient-related factors in patients undergoing potentially curative surgery for pancreatic ductal adenocarcinoma. Annals of Surgical Oncology, 18(8), pp. 2318-2328. (doi: 10.1245/s10434-011-1560-3)

McCall, P.,, Catlow, J., McArdle, P.A., McMillan, D.C. and Edwards, J. (2011) Tumoral C-reactive protein and nuclear factor kappa-B expression are associated with clinical outcome in patients with prostate cancer. Cancer Biomarkers, 10(2), pp. 91-99. (doi: 10.3233/CBM-2012-0236)

Proctor, M.J., Morrison, D.S., Talwar, D., Balmer, S.M., O'Reilly, D.S.J., Foulis, A.K., Horgan, P.G. and McMillan, D.C. (2011) An inflammation-based prognostic score (mGPS) predicts cancer survival independent of tumour site: a Glasgow Inflammation Outcome Study. British Journal of Cancer, 104(4), pp. 726-734. (doi: 10.1038/sj.bjc.6606087)

Qayyum, T.Q., McArdle, P.A., Seywright, M., McMillan, D.C. , Aitchison, M.A. and Edwards, J. (2011) The role of Src in renal cancer. British Journal of Surgery, 98(S2), p. 50. (doi: 10.1002/bjs.7523)

Reid, D., Toole, B.J., Knox, S., Talwar, D., Harten, J., O'Reilly, D.S.J., Blackwell, S., Kinsella, J., McMillan, D.C. and Wallace, A.M. (2011) The relation between acute changes in the systemic inflammatory response and plasma 25-hydroxyvitamin D concentrations after elective knee arthroplasty. American Journal of Clinical Nutrition, 93(5), pp. 1006-1011. (doi: 10.3945/ajcn.110.008490)

Richards, C.H., Leitch, E.F., Anderson, J.H., McKee, R.F., McMillan, D.C. and Horgan, P.G. (2011) The revised ACPGBI model is a simple and accurate predictor of operative mortality after potentially curative resection of colorectal cancer. Annals of Surgical Oncology, 18(13), pp. 3680-3685. (doi: 10.1245/s10434-011-1805-1)

Richards, C.H., Platt, J.J., Anderson, J.H., McKee, R.F., Horgan, P.G. and McMillan, D.C. (2011) The Impact of Perioperative Risk, Tumor Pathology and Surgical Complications on Disease Recurrence After Potentially Curative Resection of Colorectal Cancer. Annals of Surgery, 254(1), pp. 83-89. (doi: 10.1097/SLA.0b013e31821fd469)

2010

Roxburgh, C.S.D., McMillan, D.C. , Anderson, J.H., McKee, R.F., Horgan, P.G. and Foulis, A.K. (2010) Elastica staining for venous invasion results in superior prediction of cancer specific survival in colorectal cancer. Annals of Surgery, 252(6), pp. 989-997. (doi: 10.1097/SLA.0b013e3181f1c60d)

Chandrabalan, V. et al. (2010) Preoperative determinants of the length of hospital stay in patients undergoing surgery for pancreatic cancer. Pancreas, 39(8), p. 1313. (doi: 10.1097/MPA.0b013e3181f73ec0)

Vasilaki, A.T., McMillan, D.C. , Kinsella, J., Duncan, A., O’Reilly, D.S.J. and Talwar, D. (2010) Relation between riboflavin, flavin mononucleotide and flavin adenine dinucleotide concentrations in plasma and red cells in patients with critical illness. Clinica Chimica Acta, 411(21-22), pp. 1750-1755. (doi: 10.1016/j.cca.2010.07.024)

Roxburgh, C.S.D. , Wallace, A.M., Guthrie, G., Horgan, P.G. and McMillan, D.C. (2010) Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer. Colorectal Disease, 12(10), pp. 987-994. (doi: 10.1111/j.1463-1318.2009.01961.x) (PMID:19555389)

McMillan, D.C. , McArdle, C.S. and Morrison, D.S. (2010) A clinical risk score to predict 3-, 5- and 10-year survival in patients undergoing surgery for Dukes B colorectal cancer. British Journal of Cancer, 103(7), pp. 970-974. (doi: 10.1038/sj.bjc.6605864)

Chandrabalan, V. et al. (2010) The relationship between the systemic inflammatory response, patient physiology and anaerobic threshold in patients undergoing surgery for pancreatic cancer. Pancreatology, 10(2-3), p. 364. (doi: 10.1159/000314328)

Chandrabalan, V. et al. (2010) Preoperative determinants of the length of hospital stay in patients undergoing surgery for pancreatic cancer. Pancreatology, 10(2-3), p. 363. (doi: 10.1159/000314328)

Meek, C.L., Wallace, A.M., Forrest, L.M. and McMillan, D.C. (2010) The relationship between the insulin-like growth factor-1 axis, weight loss, an inflammation-based score and survival in patients with inoperable non-small cell lung cancer. Clinical Nutrition, 29(2), pp. 206-209. (doi: 10.1016/j.clnu.2009.08.013)

Roxburgh, C.S.D. and McMillan, D.C. (2010) Comparison of the Prognostic Value of Inflammation-Based Pathologic and Biochemical Criteria in Patients Undergoing Potentially Curative Resection for Colorectal Cancer Reply. Annals of Surgery, 251(2), pp. 390-391. (doi: 10.1097/SLA.0b013e3181cb8b6f)

Roxburgh, C.S.D. and McMillan, D.C. (2010) Role of systemic inflammatory response in predicting survival in patients with primary operable cancer. Future Oncology, 6(1), pp. 149-163. (doi: 10.2217/FON.09.136)[Book Review]

Crumley, A.B.C., Stuart, R., McKernan, M. and McMillan, D.C. (2010) Is hypoalbuminemia an independent prognostic factor in patients with gastric cancer? World Journal of Surgery, 34(10), pp. 2393-2398. (doi: 10.1007/s00268-010-0641-y)

Crumley, A.B.C., Stuart, R.C., McKernan, M., Going, J.J., Shearer, C.J. and McMillan, D.C. (2010) Comparison of pre-treatment clinical prognostic factors in patients with gastro-oesophageal cancer and proposal of a new staging system. Journal of Gastrointestinal Surgery, 14(5), pp. 781-787. (doi: 10.1007/s11605-010-1162-6)

Dutta, S., Horgan, P.G. and McMillan, D.C. (2010) POSSUM and its related models as predictors of postoperative mortality and morbidity in patients undergoing surgery for gastro-oesophageal cancer: a systematic review. World Journal of Surgery, 34(9), pp. 2076-2082. (doi: 10.1007/s00268-010-0685-z)

Horgan, P.G. and McMillan, D.C. (2010) Surgeons and selection of adjuvant therapy for node-negative colonic cancer. British Journal of Surgery, 97(10), pp. 1459-1460. (doi: 10.1002/bjs.7254)

McArdle, C.S., McMillan, D.C. , Greenlaw, N. and Morrison, D.S. (2010) Adjuvant radiotherapy and chemotherapy in breast cancer: 30 year follow-up of survival. BMC Cancer, 10(1), p. 398. (doi: 10.1186/1471-2407-10-398)

McArdle, P.A., Qayyum, T. and McMillan, D.C. (2010) Systemic inflammatory response and survival in patients with localised prostate cancer: 10-Year follow-up. Urologia Internationalis, 84(4), pp. 430-435. (doi: 10.1159/000313364)

McMillan, D.C. (2010) The Role of the Systemic Inflammatory Response in Predicting Outcome in Patients with Pancreatic Cancer. In: Johnson, C.D. and Imrie, C.W. (eds.) Pancreatic Disease: Protocols And Clinical Research. Springer-Verlag: Godalming, Surrey, pp. 97-102. ISBN 978-1-84882-117-0 (doi: 10.1007/978-1-84882-118-7_11)

O'Dowd, C., McRae, L.A., McMillan, D.C. , Kirk, A. and Milroy, R. (2010) Elevated preoperative C-reactive protein predicts poor cancer specific survival in patients undergoing resection for non-small cell lung cancer. Journal of Thoracic Oncology, 5(7), pp. 988-992. (doi: 10.1097/JTO.0b013e3181da78f9)

Proctor, M. J., Talwar, D., Balmar, S. M., O'Reilly, D. S. J., Foulis, A. K., Horgan, P.G. , Morrison, D. S. and McMillan, D. C. (2010) The relationship between the presence and site of cancer, an inflammation-based prognostic score and biochemical parameters. Initial results of the Glasgow Inflammation Outcome Study. British Journal of Cancer, 103(6), pp. 870-876. (doi: 10.1038/sj.bjc.6605855)

Richards, C.H., Leitch, E.F., Horgan, P.G. , Anderson, J., McKee, R.F. and McMillan, D.C. (2010) The relationship between patient physiology, the systemic inflammatory response and survival in patients undergoing curative resection of colorectal cancer. British Journal of Cancer, 103(9), pp. 1356-1361. (doi: 10.1038/sj.bjc.6605919)

Richards, C.H., Leitch, F.E., Horgan, P.G. and McMillan, D.C. (2010) A Systematic Review of POSSUM and its Related Models as Predictors of Post-operative Mortality and Morbidity in Patients Undergoing Surgery for Colorectal Cancer. Journal of Gastrointestinal Surgery, 14(10), pp. 1511-1519. (doi: 10.1007/s11605-010-1333-5)

2009

Roxburgh, C. and McMillan, D.C. (2009) Re: Ishizuka et al., systemic inflammatory response predicts postoperative outcome in patients with liver metastases from colorectal cancer. Journal of Surgical Oncology, 100(7), p. 616. (doi: 10.1002/jso.21379)

Vasilaki, A.T., Leivaditi, D., Talwar, D., Kinsella, J., Duncan, A., O'Reilly, D.S. and McMillan, D.C. (2009) Assessment of vitamin E status in patients with systemic inflammatory response syndrome: plasma, plasma corrected for lipids or red blood cell measurements? Clinica Chimica Acta, 409(1-2), pp. 41-45. (doi: 10.1016/j.cca.2009.08.008)

McMillan, D.C. and McArdle, C.S. (2009) The impact of young age on cancer-specific and non-cancer-related survival after surgery for colorectal cancer: 10-year follow-up. British Journal of Cancer, 101, pp. 557-560. (doi: 10.1038/sj.bjc.6605222)

Roxburgh, C.S., Salmond, J.M., Horgan, P.G., Oien, K.A. and McMillan, D.C. (2009) Tumour inflammatory infiltrate predicts survival following curative resection for node-negative colorectal cancer. European Journal of Cancer, 45(12), pp. 2138-2145. (doi: 10.1016/j.ejca.2009.04.011)

McMillan, D.C. (2009) Systemic inflammation, nutritional status and survival in patients with cancer. Current Opinion in Clinical Nutrition and Metabolic Care, 12(3), pp. 223-226. (doi: 10.1097/MCO.0b013e32832a7902)

Roxburgh, C.S.D., Salmond, J.M., Horgan, P.G. , Oien, K.A. and McMillan, D.C. (2009) Comparison of the prognostic value of inflammation based pathological and biochemical criteria in patients undergoing potentially curative resection for colorectal cancer. Annals of Surgery, 249(5), pp. 788-793. (doi: 10.1097/SLA.0b013e3181a3e738)

Crozier, J.E., Leitch, E.F., McKee, R.F., Anderson, J.H., Horgan, P.G. and McMillan, D.C. (2009) Relationship between emergency presentation, systemic inflammatory response, and cancer-specific survival in patients undergoing potentially curative surgery for colon cancer. American Journal of Surgery, 197(4), pp. 544-549. (doi: 10.1016/j.amjsurg.2007.12.052)

Moyes, L.H., Leitch, E.F., McKee, R.F., Anderson, J.H., Horgan, P.G. and McMillan, D.C. (2009) Preoperative systemic inflammation predicts postoperative infectious complications in patients undergoing curative resection for colorectal cancer. British Journal of Cancer, 100(8), pp. 1236-1239. (doi: 10.1038/sj.bjc.6604997)

Roxburgh, C.S.D. , Crozier, J.E.M., Maxwell, F., Foulis, A.K., Brown, J., McKee, R.F., Anderson, J.H., Horgan, P.G. and McMillan, D.C. (2009) Comparison of tumour-based (Petersen Index) and inflammation-based (Glasgow Prognostic Score) scoring systems in patients undergoing curative resection for colon cancer. British Journal of Cancer, 100(5), pp. 701-706. (doi: 10.1038/sj.bjc.6604926)

Moyes, L. and McMillan, D. (2009) Glasgow Prognostic Score as a predictive factor differentiating surgical site infection and remote infection following colorectal cancer surgery? Reply. British Journal of Cancer, 101(9), p. 1650.

Roxburgh, C.S.D., Salmond, J.M., Horgan, P.G. , Oien, K.A. and McMillan, D.C. (2009) The relationship between the local and systemic inflammatory responses and survival in patients undergoing curative surgery for colon and rectal cancers. Journal of Gastrointestinal Surgery, 13(11), pp. 2011-2019. (doi: 10.1007/s11605-009-1034-0)

Stevenson, R.D., Ingram, A., Leung, H.Y., McMillan, D.C. and Graham, D. (2009) Quantitative SERRS immunoassay for the detection of human PSA. Analyst, 134(5), pp. 842-844. (doi: 10.1039/B902174D)

2008

Leung, E.Y.L. , Crozier, J.E.M., Talwar, D., O'Reilly, D.S.J., McKee, R.F., Horgan, P.G. and McMillan, D.C. (2008) Vitamin antioxidants, lipid peroxidation, tumour stage, the systemic inflammatory response and survivial in patients with colorectal cancer. International Journal of Cancer, 123(10), pp. 2460-2464. (doi: 10.1002/ijc.23811) (PMID:18729200)

Al Murri, A.M., Hilmy, M., Bell, J., Wilson, C., McNicol, A.-M., Lannigan, A., Doughty, J.C. and McMillan, D.C. (2008) The relationship between the systemic inflammatory response, tumour proliferative activity, T-lymphocytic and macrophage infiltration, microvessel density and survival in patients with primary operable breast cancer. British Journal of Cancer, 99(7), pp. 1013-1019. (doi: 10.1038/sj.bjc.6604667)

Canna, K., Hilmy, M., McMillan, D.C., Smith, G.W., McKee, R.F., McArdle, C.S. and McNicol, A. (2008) The relationship between tumour proliferative activity, the systemic inflammatory response and survival in patients undergoing curative resection for colorectal cancer. Colorectal Disease, 10(7), pp. 663-667. (doi: 10.1111/j.1463-1318.2007.01416.x)

McMillan, D.C. , Hole, D.J. and McArdle, C.S. (2008) The impact of old age on cancer-specific and non-cancer-related survival following elective potentially curative surgery for Dukes A/B colorectal cancer. British Journal of Cancer, 99, pp. 1046-1049. (doi: 10.1038/sj.bjc.6604669)

Crumley, A.B.C., Stuart, R.C., McKernan, M., McDonald, A.C. and McMillan, D.C. (2008) Comparison of an inflammation-based prognostic score (GPS) with performance status (ECOG-ps) in patients receiving palliative chemotherapy for gastroesophageal cancer. Journal of Gastroenterology and Hepatology, 23(8), E325-E329. (doi: 10.1111/j.1440-1746.2007.05105.x)

McMillan, D.C. (2008) An inflammation-based prognostic score and its role in the nutrition-based management of patients with cancer. Proceedings of the Nutrition Society, 67(3), pp. 257-262.

Ramsey, S., Aitchison, M., Graham, J. and McMillan, D.C. (2008) The longitudinal relationship between the systemic inflammatory response, circulating T-lymphocytes, interleukin-6 and -10 in patients undergoing immunotherapy for metastatic renal cancer. BJU International, 102(1), pp. 125-129. (doi: 10.1111/j.1464-410X.2008.07466.x)

Vasilaki, A. T. , McMillan, D. C. , Kinsella, J., Duncan, A., O'Reilly, D. S. J. and Talwar, D. (2008) Relation between pyridoxal and pyridoxal phosphate concentrations in plasma, red cells, and white cells in patients with critical illness. American Journal of Clinical Nutrition, 88(1), pp. 140-146. (doi: 10.1093/ajcn/88.1.140) (PMID:18614734)

Harten, J., Crozier, J.E.M., McCreath, B., Hay, A., McMillan, D.C., McArdle, C.S. and Kinsella, J. (2008) Effect of intraoperative fluid optimisation on renal function in patients undergoing emergency abdominal surgery; a randomised controlled pilot study (ISRCTN 11799696) Fluid optimisation for emergency surgery. International Journal of Surgery, 6(3), pp. 197-204. (doi: 10.1016/j.ijsu.2008.03.002)

Lamb, G.W., McArdle, P.A., Ramsey, S., McNichol, A.M., Edwards, J. , Aitchison, M. and McMillan, D.C. (2008) The relationship between the local and systemic inflammatory responses and survival in patients undergoing resection for localized renal cancer. BJU International, 102(6), pp. 756-761. (doi: 10.1111/j.1464-410X.2008.07666.x)

Ramsey, S., Lamb, G.W.A., Aitchison, M. and McMillan, D.C. (2008) Prospective study of the relationship between the systemic inflammatory response, prognostic scoring systems and relapse-free and cancer-specific survival in patients undergoing potentially curative resection for renal cancer. BJU International, 101(8), pp. 959-963. (doi: 10.1111/j.1464-410X.2007.07363.x)

McKernan, M., McMillan, D.C. , Anderson, J.R., Angerson, W.J. and Stuart, R.C. (2008) The relationship between quality of life (EORTC QLQ-C30) and survival in patients with gastro-oesopohageal cancer. British Journal of Cancer, 98(5), pp. 888-893. (doi: 10.1038/sj.bjc.6604248)

Mckay, C.J., Glen, P. and McMillan, D.C. (2008) Chronic inflammation and pancreatic cancer. Best Practice and Research: Clinical Gastroenterology, 22(1), pp. 65-73. (doi: 10.1016/j.bpg.2007.11.007)