Emergent motility and intrinsic pattern robustness: multiscale modelling motivated by Jeffery and Turing

Dr Mohit Dalwadi (University of Oxford)

Thursday 3rd October 14:00-15:00 Maths 311B

Abstract

In this talk I use multiscale mathematics to understand two emergent phenomena related to fundamental problems in fluids and biology.

In the first part, I discuss an overarching question in developmental biology: how is it that cells are able to decode spatio-temporally varying signals into functionally robust patterns in the presence of confounding effects caused by unpredictable or heterogeneous environments? This is linked to the general idea first explored by Alan Turing in the 1950s. I present a general theory of pattern formation in the presence of spatio-temporal input variations, and use multiscale mathematics to show how biological systems can generate non-standard dynamic robustness for 'free' over physiologically relevant timescales. 

In the second part, I investigate how the rapid motion of 3D microswimmers affects their emergent (observed) trajectories in shear flow. This is an active version of the classic fluid mechanics result of Jeffery's orbits for inert spheroids, first explored by George Jeffery in the 1920s. I show that the short-scale rapid motion exhibited by many microswimmers can have a significant effect on longer-scale trajectories, despite the common neglect of this motion in some mathematical models, and how to systematically incorporate this effect into modified versions of Jeffery's original equations.

Add to your calendar

Download event information as iCalendar file (only this event)