Professor Stefan Siebert
- Professor of Inflammation Medicine and Rheumatology (Immunology & Infection)
telephone:
01413303375
email:
Stefan.Siebert@glasgow.ac.uk
School of Infection & Immunity, Room B417 Fourth Floor, Sir Graeme Davies Building, 120 University Place
https://orcid.org/0000-0002-1802-7311Biography
Professor Stefan Siebert is a Professor of Inflammation Medicine and Rheumatology at the University of Glasgow and Honorary Consultant Rheumatologist with NHS Greater Glasgow and Clyde.
As clinical researcher, he is involved in managing patients with rheumatoid and other types of inflammatory arthritis, studying mechanisms that underlie these conditions and running clinical trials of new therapies.
Prof Siebert has a particular interest in psoriatic arthritis and spondyloarthritis, and in comparing how the underlying immune processes differ from rheumatoid arthritis.
This approach has the potential to yield information about the underlying mechanisms and possible therapeutic targets for each of these conditions.
He is also interested in understanding the effects of current arthritis therapies using a variety of immunological, laboratory and health informatics approaches.
Publications
2024
Colton, H. et al. (2024) Greater preservation of SARS‐CoV‐2 neutralising antibody responses following the ChAdOx1‐S (AZD1222) vaccine compared with mRNA vaccines in haematopoietic cell transplant recipients. British Journal of Haematology, (doi: 10.1111/bjh.19874) (PMID:39551718) (Early Online Publication)
Siebert, S. , Schett, G., Raychaudhuri, S. P., Guma, M., Chen, W., Gao, S., Chakravarty, S. D., Lavie, F. and Rahman, P. (2024) Correlation of changes in inflammatory and collagen biomarkers with durable guselkumab Efficacy through 2 years in participants with active psoriatic arthritis: results from a phase III randomized controlled trial. Therapeutic Advances in Musculoskeletal Disease, 16, 1759720X241283536. (doi: 10.1177/1759720X241283536)
Gray, S. R. , Montoye, A. H.K., Vondrasek, J. D., Neph, S., Siebert, S. , Paul, L., Bachmair, E. M. and Basu, N. (2024) Associations of physical activity levels with fatigue in people with inflammatory rheumatic disease in the LIFT trial. Rheumatology Advances in Practice, (Accepted for Publication)
Siebert, S. et al. (2024) Modulation of IL‐23 signaling with guselkumab in biologic‐naïve patients versus TNF inhibitor‐inadequate responders with active psoriatic arthritis. Arthritis and Rheumatology, 76(6), pp. 894-904. (doi: 10.1002/art.42803) (PMID:38253404)
Goodyear, C. S. et al. (2024) Immunogenicity of third dose COVID-19 vaccine strategies in patients who are immunocompromised with suboptimal immunity following two doses (OCTAVE-DUO): an open-label, multicentre, randomised, controlled, phase 3 trial. Lancet Rheumatology, 6(6), e339-e351. (doi: 10.1016/S2665-9913(24)00065-1) (PMID:38734019)
Vassilakis, K. D., Magiouf, K., Siebert, S. and Fragoulis, G. E. (2024) Selective JAK-inhibitors in spondyloarthritis. Mediterranean Journal of Rheumatology, 35(Suppl1), pp. 27-36. (doi: 10.31138/mjr.311023.sji) (PMID:38756935) (PMCID:PMC11094441)
Coates, L. C. et al. (2024) Enhancing current guidance for psoriatic arthritis and its comorbidities: recommendations from an expert consensus panel. Rheumatology, (doi: 10.1093/rheumatology/keae172) (PMID:38490262) (Early Online Publication)
Cope, A. P. et al. (2024) Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): A randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial. Lancet, 403(10429), pp. 838-849. (doi: 10.1016/S0140-6736(23)02649-1) (PMID:38364839)
Marzo-Ortega, H. et al. (2024) Time to address the challenge of difficult to treat psoriatic arthritis: Results from an international survey. Annals of the Rheumatic Diseases, 83(3), pp. 403-404. (doi: 10.1136/ard-2023-225087) (PMID:37963707)
Siebert, S. and Marzo-Ortega, H. (2024) Difficult-to-treat psoriatic arthritis: Moving out of the rheumatoid arthritis shadow. Nature Reviews Rheumatology, 20(3), pp. 135-136. (doi: 10.1038/s41584-024-01083-y) (PMID:38279015)
Laurie, E. , Siebert, S. , Yongolo, N., Halliday, J. , Biswaro, S., Krauth, S. J. , Kilonzo, K., Mmbaga, B. T., McIntosh, E. and NIHR Global Health Group, . (2024) Evidencing the clinical and economic burden of musculoskeletal disorders in Tanzania: Paving the way for urgent rheumatology service development. Rheumatology Advances in Practice, 8(1), rkad110. (doi: 10.1093/rap/rkad110) (PMID:38143512) (PMCID:PMC10748784)
Yongolo, N. M. et al. (2024) Estimating the prevalence and predictors of musculoskeletal disorders in Tanzania: a cross-sectional pilot study. Pan African Medical Journal, 47, 36. (doi: 10.11604/pamj.2024.47.36.38258)
2023
Chong, H. Y. et al. (2023) Cost-effectiveness of cognitive behavioural and personalised exercise interventions for reducing fatigue in inflammatory rheumatic diseases. Rheumatology, 62(12), pp. 3819-3827. (doi: 10.1093/rheumatology/kead157) (PMID:37018151)
Van Kuijk, A. W.R. et al. (2023) Gender-specific differences in patients with psoriatic arthritis receiving ustekinumab or tumour necrosis factor inhibitor: real-world data. Rheumatology, 62(10), pp. 3382-3390. (doi: 10.1093/rheumatology/kead089) (PMID:36810788) (PMCID:PMC10547514)
Schett, G., Chen, W., Gao, S., Chakravarty, S. D., Shawi, M., Lavie, F., Zimmermann, M., Sharaf, M., Coates, L. C. and Siebert, S. (2023) Correction: Effect of guselkumab on serum biomarkers in patients with active psoriatic arthritis and inadequate response to tumor necrosis factor inhibitors: results from the COSMOS phase 3b study. Arthritis Research and Therapy, 25(1), 170. (doi: 10.1186/s13075-023-03158-9) (PMID:37715280) (PMCID:PMC10503169)
FitzGerald, O. et al. (2023) Application of clinical and molecular profiling data to improve patient outcomes in psoriatic arthritis. Therapeutic Advances in Musculoskeletal Disease, 15, pp. 1-14. (doi: 10.1177/1759720x231192315) (PMID:37694182) (PMCID:PMC10492462)
Ooms, A. et al. (2023) Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis. BMJ Open, 13(9), e078539. (doi: 10.1136/bmjopen-2023-078539) (PMID:37770264) (PMCID:PMC10546161)
O’Brien, C. M. et al. (2023) Number of days required to measure sedentary time and physical activity using accelerometery in rheumatoid arthritis: a reliability study. Rheumatology International, 43(8), pp. 1459-1465. (doi: 10.1007/s00296-023-05342-1) (PMID:37227468) (PMCID:PMC10261182)
Moshi, B. et al. (2023) Trends of frequency, mortality and risk factors among patients admitted with stroke from 2017 to 2019 to the medical ward at Kilimanjaro Christian Medical Centre hospital: a retrospective observational study. BMJ Open, 13(7), e071918. (doi: 10.1136/bmjopen-2023-071918) (PMID:37524544) (PMCID:PMC10391824)
Siebert, S. and Marzo-Ortega, H. (2023) Correspondence on ‘No efficacy of anti-IL-23 therapy for axial spondyloarthritis in randomised controlled trials but in post-hoc analyses of psoriatic arthritis-related ‘physician-reported spondylitis’?’ by Braun and Landewé. Annals of the Rheumatic Diseases, 82(8), e185. (doi: 10.1136/annrheumdis-2021-221799) (PMID:34844925)
Barnes, E. et al. (2023) SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease. Nature Medicine, 29(7), pp. 1760-1774. (doi: 10.1038/s41591-023-02414-4) (PMID:37414897) (PMCID:PMC10353927)
Gossec, L. et al. (2023) Improvement in patient-reported outcomes and work productivity following 3-year ustekinumab or tumour necrosis factor inhibitor treatment in patients with psoriatic arthritis: results from the PsABio real-world study. Arthritis Research and Therapy, 25, 109. (doi: 10.1186/s13075-023-03058-y) (PMID:37353788) (PMCID:PMC10288720)
Gossec, L., Theander, E., Chakravarty, S. D., Bergmans, P., Lavie, F., Noël, W., Sharaf, M., Siebert, S. and Smolen, J. S. (2023) Response to treatment in psoriatic arthritis, the effect of age: analysis of patients receiving ustekinumab in the PsABio real-world study. Arthritis Research and Therapy, 25, 100. (doi: 10.1186/s13075-023-03078-8) (PMID:37296456) (PMCID:PMC10251537)
Gad Kilonzo, K. et al. (2023) Estimating the prevalence, quality of life, economic and societal impact of arthritis in Tanzania: protocol for a mixed methods study. [Protocols]
Gad Kilonzo, K. et al. (2023) Analysis of qualitative data, Statistical Analysis and Health Economic Analysis. [Protocols]
Gad Kilonzo, K. et al. (2023) Data storage and security. [Protocols]
Gad Kilonzo, K. et al. (2023) Laboratory and radiological data collection. [Protocols]
Kilonzo, K. G. et al. (2023) Community-based cross-sectional survey. [Protocols]
Kilonzo, K. G. et al. (2023) Estimating the prevalence, quality of life, economic and societal impact of arthritis in Tanzania: protocol for a mixed methods study. [Protocols]
Kilonzo, K. G. et al. (2023) Qualitative methods. [Protocols]
Johnsson, H., Cole, J., McInnes, I. B. , Graham, G. and Siebert, S. (2023) Differences in transcriptional changes in psoriasis and psoriatic arthritis skin with immunoglobulin gene enrichment in psoriatic arthritis. Rheumatology, (doi: 10.1093/rheumatology/kead195) (PMID:37137278) (Early Online Publication)
Johnsson, H., Cole, J., Siebert, S. , McInnes, I. B. and Graham, G. (2023) Cutaneous lesions in psoriatic arthritis are enriched in chemokine transcriptomic pathways. Arthritis Research and Therapy, 25, 73. (doi: 10.1186/s13075-023-03034-6) (PMID:37131254) (PMCID:PMC10152590)
Winthrop, K. L. et al. (2023) Unmet need in rheumatology: reports from the Advances in Targeted Therapies meeting, 2022. Annals of the Rheumatic Diseases, 82(5), pp. 594-598. (doi: 10.1136/ard-2022-223528) (PMID:36702529)
Gossec, L. et al. (2023) Long-term effectiveness and persistence of ustekinumab and TNF inhibitors in patients with psoriatic arthritis: final 3-year results from the PsABio real-world study. Annals of the Rheumatic Diseases, 82(4), pp. 496-506. (doi: 10.1136/ard-2022-222879) (PMID:36600178) (PMCID:PMC10086293)
Siebert, S. , Behrens, F., Lubrano, E., Martin, N., Sharaf, M., Contré, C., Theander, E., Queiro, R., Zimmermann, M. and Gossec, L. (2023) PsABIOnd study and eDaily substudy design: long-term effectiveness and safety of guselkumab and IL-17 inhibitors in routine clinical practice in patients with psoriatic arthritis. Rheumatology and Therapy, 10(2), pp. 489-505. (doi: 10.1007/s40744-022-00518-w) (PMID:36585602)
Kennedy, J., Kennedy, N., Cooksey, R., Choy, E., Siebert, S. , Rahman, M. and Brophy, S. (2023) Predicting a diagnosis of ankylosing spondylitis using primary care health records–a machine learning approach. PLoS ONE, 18(3), e0279076. (doi: 10.1371/journal.pone.0279076) (PMID:37000839) (PMCID:PMC10065228)
Najm, A. , Goodyear, C. S. , McInnes, I. B. and Siebert, S. (2023) Phenotypic heterogeneity in psoriatic arthritis: towards tissue pathology-based therapy. Nature Reviews Rheumatology, 19, pp. 153-165. (doi: 10.1038/s41584-022-00874-5) (PMID:36596924)
Morton, F. R. , Jani, B. D. , Mair, F. S. , McLoone, P. , Canning, J., Macdonald, S. , McQueenie, R., Siebert, S. and Nicholl, B. I. (2023) Association between risk, duration and cause of hospitalisations in people with rheumatoid arthritis and multimorbidity in the UK Biobank and Scottish Early Rheumatoid Arthritis (SERA) cohorts: longitudinal observational study. Seminars in Arthritis and Rheumatism, 58, 152130. (doi: 10.1016/j.semarthrit.2022.152130) (PMID:36459724)
Nyirenda, M. H., Nijjar, J. S., Frleta-Gilchrist, M., Gilchrist, D. S., Porter, D., Siebert, S. , Goodyear, C. S. and McInnes, I. B. (2023) JAK inhibitors disrupt T cell-induced proinflammatory macrophage activation. RMD Open, 9(1), e002671. (doi: 10.1136/rmdopen-2022-002671) (PMID:36599629) (PMCID:PMC9815080)
McLoone, P. , Jani, B. D. , Siebert, S. , Morton, F. R. , Canning, J., Macdonald, S. , Mair, F. S. and Nicholl, B. I. (2023) Classification of long-term condition patterns in rheumatoid arthritis and associations with adverse health events: a UK Biobank cohort study. Journal of Multimorbidity and Comorbidity, 13, p. 26335565221148616. (doi: 10.1177/26335565221148616) (PMID:36798088) (PMCID:PMC9926377)
Zhao, S. S. et al. (2023) Treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 7(2), rkad039. (doi: 10.1093/rap/rkad039) (PMID:37197377) (PMCID:PMC10183299)
2022
Stanciu, I., Anderson, J. , Siebert, S. , Mackay, D. and Lyall, D. M. (2022) Associations of mental health, sleep and cognition characteristics with rheumatoid arthritis and rheumatoid factor in the UK Biobank. Scientific Reports, 12, 19844. (doi: 10.1038/s41598-022-22021-6) (PMID:36400784) (PMCID:PMC9674828)
Fragoulis, G. E. and Siebert, S. (2022) The role of IL-23 and the use IL-23 inhibitors in psoriatic arthritis. Musculoskeletal Care, 20(S1), S12-S21. (doi: 10.1002/msc.1694) (PMID:36069174)
Fragoulis, G. E., Nikiphorou, E., McInnes, I. B. and Siebert, S. (2022) Does age matter in psoriatic arthritis? A narrative review. Journal of Rheumatology, 49(10), pp. 1085-1091. (doi: 10.3899/jrheum.210349) (PMID:34393099)
Hanlon, P. , Morrison, H., Morton, F. , Jani, B. D. , Siebert, S. , Lewsey, J. , McAllister, D. and Mair, F. S. (2022) Frailty in people with rheumatoid arthritis: a systematic review of observational studies. Wellcome Open Research, 6, 244. (doi: 10.12688/wellcomeopenres.17208.2)
Canning, J., Siebert, S. , Jani, B. , Harding-Edgar, L., Kempe, I., Mair, F. S. and Nicholl, B. I. (2022) Examining the relationship between rheumatoid arthritis, multimorbidity and adverse health-related outcomes: a systematic review. Arthritis Care and Research, 74(9), pp. 1500-1512. (doi: 10.1002/acr.24587) (PMID:33650196)
Tucker, L. et al. (2022) The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs. Rheumatology, 61(9), e255-e266. (doi: 10.1093/rheumatology/keac295) (PMID:35640657)
Tucker, L. et al. (2022) Executive summary: The 2022 British Society for Rheumatology guideline for the treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs. Rheumatology, 61(9), pp. 2514-3520. (doi: 10.1093/rheumatology/keac260) (PMID:35640653)
Ogdie, A., Lindsay, C. A., Mease, P. J., Callis Duffin, K., Rosen, C. F. and Siebert, S. (2022) Challenges in the diagnosis and assessment of psoriatic arthritis. Journal of Rheumatology, 49(6 Sup1), pp. 64-67. (doi: 10.3899/jrheum.211337) (PMID:35428713)
Gossec, L. et al. (2022) Persistence and effectiveness of the IL-12/23 pathway inhibitor ustekinumab or tumour necrosis factor inhibitor treatment in patients with psoriatic arthritis: 1-year results from the real-world PsABio Study. Annals of the Rheumatic Diseases, 81, pp. 823-830. (doi: 10.1136/annrheumdis-2021-221640) (PMID:35210262)
Ferguson, L. D. et al. (2022) Effect of the phosphodiesterase 4 inhibitor apremilast on cardiometabolic outcomes in psoriatic disease – results of the Immune Metabolic Associations in Psoriatic Arthritis study. Rheumatology, 61(3), pp. 1026-1034. (doi: 10.1093/rheumatology/keab474) (PMID:34097014) (PMCID:PMC8889283)
Mirza, M. et al. (2022) Impact of the COVID‐19 pandemic on recruitment to clinical research studies in rheumatology. Musculoskeletal Care, 20(1), pp. 209-213. (doi: 10.1002/msc.1561) (PMID:33938621) (PMCID:PMC8242596)
Docherty, S., Harley, R., McAuley, J. J., Crowe, L. A.N., Padret, C., Kirwan, P. D., Siebert, S. and Millar, N. L. (2022) The effect of exercise on cytokines: implications for musculoskeletal health: a narrative review. BMC Sports Science, Medicine and Rehabilitation, 14(1), 5. (doi: 10.1186/s13102-022-00397-2) (PMID:34991697) (PMCID:PMC8740100)
Hanlon, P. , Morton, F. , Siebert, S. , Jani, B. D. , Nicholl, B. I. , Lewsey, J. , McAllister, D. and Mair, F. S. (2022) Frailty in rheumatoid arthritis and its relationship with disease activity, hospitalisation and mortality: a longitudinal analysis of the Scottish Early Rheumatoid Arthritis cohort and UK Biobank. RMD Open, 8(1), e002111. (doi: 10.1136/rmdopen-2021-002111) (PMID:35292529) (PMCID:PMC8928366)
Hsieh, P. H., Geue, C. , Wu, O. , McIntosh, E. and Siebert, S. (2022) How do multiple long-term conditions impact on the cost-of-illness in early rheumatoid arthritis? RMD Open, 8, e002454. (doi: 10.1136/rmdopen-2022-002454) (PMID:36104116) (PMCID:PMC9476122)
2021
McPeake, J. et al. (2021) Long-term outcomes following severe COVID-19 infection: a multicentre cohort study of family member outcomes. Annals of the American Thoracic Society, 18(12), pp. 2098-2101. (doi: 10.1513/AnnalsATS.202104-481RL) (PMID:34192506) (PMCID:PMC8641813)
Fragoulis, G. E., Brock, J., Basu, N. , McInnes, I. B. and Siebert, S. (2021) The role for JAK inhibitors in the treatment of immune-mediated rheumatic and related conditions. Journal of Allergy and Clinical Immunology, 148(4), pp. 941-952. (doi: 10.1016/j.jaci.2021.08.010) (PMID:34450118)
Petermann-Rocha, F., Ferguson, L. D. , Gray, S. R. , Rodríguez-Gómez, I., Sattar, N. , Siebert, S. , Ho, F. K., Pell, J. P. and Celis-Morales, C. (2021) Association of sarcopenia with incident osteoporosis: a prospective study of 168,682 UK biobank participants. Journal of Cachexia, Sarcopenia and Muscle, 12(5), pp. 1179-1188. (doi: 10.1002/jcsm.12757) (PMID:34264024) (PMCID:PMC8517357)
Siebert, S. and Sattar, N. (2021) Estimating cardiovascular impacts of drugs for psoriatic disease: a long way to go. Journal of Investigative Dermatology, 141(10), pp. 2322-2325. (doi: 10.1016/j.jid.2021.04.012) (PMID:34560915)
Ansalone, C. , Cole, J., Chilaka, S., Sunzini, F., Sood, S., Robertson, J., Siebert, S. , McInnes, I. B. and Goodyear, C. (2021) TNF is a homeostatic regulator of distinct epigenetically primed human osteoclast precursors. Annals of the Rheumatic Diseases, 80(6), pp. 748-757. (doi: 10.1136/annrheumdis-2020-219262) (PMID:33692019) (PMCID:PMC8142443)
Derakhshan, M. H., Morton, F. , Fragoulis, G. E., Paterson, C., Dale, J., Basu, N. , Mcinnes, I., Porter, D. and Siebert, S. (2021) Opioids and analgesic use in early rheumatoid arthritis: a longitudinal analysis of linked real-world prescription data. Annals of the Rheumatic Diseases 80(S1): 1159. EULAR 2021 Virtual Congress., 2-5 June 2021. (doi: 10.1136/annrheumdis-2021-eular.2672)
Pratt, A. G. et al. (2021) Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial. Lancet Rheumatology, 3(5), e337-e346. (doi: 10.1016/S2665-9913(21)00061-8) (PMID:33928262) (PMCID:PMC8062952)
Sweet, K., Song, Q., Loza, M. J., McInnes, I. B. , Ma, K., Leander, K., Lakshminarayanan, V., Franks, C., Cooper, P. and Siebert, S. (2021) Guselkumab induces robust reduction in acute phase proteins and type 17 effector cytokines in active psoriatic arthritis: results from phase 3 trials. RMD Open, 7(2), e001679. (doi: 10.1136/rmdopen-2021-001679) (PMID:34011674) (PMCID:PMC8137258)
Ferguson, L. D. , Linge, J., Leinhard, O. D., Woodward, R., Hall Barrientos, P., Roditi, G., Radjenovic, A. , McInnes, I. B. , Siebert, S. and Sattar, N. (2021) Psoriatic arthritis is associated with adverse body composition predictive of greater coronary heart disease and type 2 diabetes propensity – a cross-sectional study. Rheumatology, 60(4), pp. 1858-1862. (doi: 10.1093/rheumatology/keaa604) (PMID:33147607)
Cole, M., Yap, C., Buckley, C., Ng, W. F., McInnes, I. , Filer, A., Siebert, S. , Pratt, A., Isaacs, J. D. and Stocken, D. D. (2021) TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis. Trials, 22(1), 433. (doi: 10.1186/s13063-021-05384-5) (PMID:34229728) (PMCID:PMC8259060)
Jones, G. T., Macfarlane, G. J., Forrest Keenan, K., McNamee, P., Neilson, A. R., Siebert, S. , Burden, A. D., Kay, L. and Helliwell, P. S. (2021) The BSR-PsA: study protocol for the British Society for Rheumatology psoriatic arthritis register. BMC Rheumatology, 5, 19. (doi: 10.1186/s41927-021-00189-0) (PMID:33993880) (PMCID:PMC8126428)
McPeake, J. et al. (2021) Long-term outcomes following severe COVID-19 infection: a propensity matched cohort study. BMJ Open Respiratory Research, 8, e001080. (doi: 10.1136/bmjresp-2021-001080)
McQueenie, R., Jani, B. D. , Siebert, S. , McCowan, C. , Macdonald, S. , Mair, F. S. and Nicholl, B. I. (2021) Prevalence of chronic pain in LTCs and multimorbidity: a cross-sectional study using UK Biobank. Journal of Multimorbidity and Comorbidity, 11, p. 26335565211005870. (doi: 10.1177/26335565211005870)
Rayner, F. et al. (2021) BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study. BMC Rheumatology, 5, 22. (doi: 10.1186/s41927-021-00194-3) (PMID:34275488) (PMCID:PMC8286860)
2020
McQueenie, R., Nicholl, B. I. , Jani, B. D. , Canning, J., Macdonald, S. , McCowan, C. , Neary, J. , Browne, S. , Mair, F. S. and Siebert, S. (2020) Patterns of multimorbidity and their effects on adverse outcomes in rheumatoid arthritis: a study of 5658 UK Biobank participants. BMJ Open, 10(11), e038829. (doi: 10.1136/bmjopen-2020-038829) (PMID:33234629) (PMCID:PMC7684828)
Fragoulis, G. E., Cavanagh, J. , Tindell, A., Derakhshan, M., Paterson, C., Porter, D., McInnes, I. B. and Siebert, S. (2020) Depression and anxiety in an Early Rheumatoid Arthritis inception cohort. Associations with demographic, socioeconomic and disease features. RMD Open, 6, e001376. (doi: 10.1136/rmdopen-2020-001376) (PMID:33127857)
Hanlon, P. , Butterly, E., Lewsey, J. , Siebert, S. , Mair, F. S. and McAllister, D. A. (2020) Identifying frailty in trials: an analysis of individual participant data from trials of novel pharmacological interventions. BMC Medicine, 18, 309. (doi: 10.1186/s12916-020-01752-1) (PMID:33087107) (PMCID:PMC7579922)
Porter, D., Basu, N. and Siebert, S. (2020) Classification criteria: time for a rethink? Annals of the Rheumatic Diseases, 79(10), pp. 1264-1266. (doi: 10.1136/annrheumdis-2020-217769) (PMID:32699035)
Derakhshan, M. H., Dean, L. E., Jones, G. T., Siebert, S. and Gaffney, K. (2020) Predictors of extra-articular manifestations in axial spondyloarthritis and their influence on TNF-inhibitor prescribing patterns: results from the British Society for Rheumatology Biologics Register for Ankylosing Spondylitis. RMD Open, 6, e001206. (doi: 10.1136/rmdopen-2020-001206) (PMID:32641447)
Siebert, S. , McGucken, A. and McInnes, I. B. (2020) The IL-23/IL-17A axis in spondyloarthritis: therapeutics informing pathogenesis? Current Opinion in Rheumatology, 32(4), pp. 349-356. (doi: 10.1097/BOR.0000000000000719) (PMID:32412997)
Siebert, S. et al. (2020) Targeting the rheumatoid arthritis synovial fibroblast via cyclin dependent kinase inhibition: an early phase trial. Medicine, 99(26), e20458. (doi: 10.1097/MD.0000000000020458) (PMID:32590730) (PMCID:PMC7328978)
Hsieh, P.-H., Wu, O. , Geue, C. , McIntosh, E. , McInnes, I. B. and Siebert, S. (2020) The economic burden of rheumatoid arthritis: a systematic review of literature in biologic era. Annals of the Rheumatic Diseases, 79(6), pp. 771-777. (doi: 10.1136/annrheumdis-2019-216243) (PMID:32245893)
Keat, A., Bennett, A. N., Gaffney, K., Jones, G. T., Martindale, J., Sengupta, R., Siebert, S. and Marzo-Ortega, H. (2020) BRITSpA at five. Rheumatology, 59(4), pp. 699-701. (doi: 10.1093/rheumatology/kez523) (PMID:31710687)
Coulter, E. H. , McDonald, M. T., Cameron, S., Siebert, S. and Paul, L. (2020) Physical activity and sedentary behaviour and their associations with clinical measures in axial spondyloarthritis. Rheumatology International, 40, pp. 375-381. (doi: 10.1007/s00296-019-04494-3) (PMID:31848736) (PMCID:PMC7002460)
Bain, K.A. et al. (2020) Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease‐associated psychological morbidity. British Journal of Dermatology, 182(1), pp. 130-137. (doi: 10.1111/bjd.18008) (PMID:30980732)
Canning, J., Siebert, S. , Jani, B. D. , Mair, F. S. and Nicholl, B. I. (2020) Examining the relationship between rheumatoid arthritis, multimorbidity and adverse health-related outcomes: a systematic review protocol. Journal of Comorbidity, 10, pp. 1-5. (doi: 10.1177/2235042X20906657)
Sunzini, F., McInnes, I. and Siebert, S. (2020) JAK inhibitors and infections risk: focus on herpes zoster. Therapeutic Advances in Musculoskeletal Disease, 12, 1759720X20936059. (doi: 10.1177/1759720X20936059) (PMID:32655703) (PMCID:PMC7328488)
2019
Ferguson, L. D. , Brown, R., Celis-Morales, C. , Welsh, P. , Lyall, D. M. , Pell, J. P. , McInnes, I. B. , Siebert, S. and Sattar, N. (2019) Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank. Rheumatology, 58(12), pp. 2137-2142. (doi: 10.1093/rheumatology/kez192) (PMID:31131407) (PMCID:PMC6880847)
Ferguson, L. , Welsh, P. , Brown, R., Tindell, A., Kerrigan, S., Sattar, N. , McInnes, I. and Siebert, S. (2019) Effect of Phosphodiesterase 4 Inhibition with Apremilast on Cardiometabolic Outcomes in Psoriatic Arthritis – Initial Results from the Immune Metabolic Associations in Psoriatic Arthritis (IMAPA) Study. In: 2019 ACR/ARP Annual Meeting, Atlanta, GA, 8-13 November 2019,
Siebert, S. , Sweet, K., Dasgupta, B., Campbell, K., McInnes, I. B. and Loza, M. J. (2019) Responsiveness of serum C‐reactive protein, interleukin‐17A, and interleukin‐17F levels to ustekinumab in psoriatic arthritis: lessons from two phase III, multicenter, double‐blind, placebo‐controlled trials. Arthritis and Rheumatology, 71(10), pp. 1660-1669. (doi: 10.1002/art.40921) (PMID:31070869)
Zhao, S. S., Radner, H., Siebert, S. , Duffield, S. J., Thong, D., Hughes, D. M., Moots, R. J., Solomon, D. H. and Goodson, N. J. (2019) Comorbidity burden in axial spondyloarthritis: a cluster analysis. Rheumatology, 58(10), pp. 1746-1754. (doi: 10.1093/rheumatology/kez119) (PMID:31220322)
Kitas, G. D. et al. (2019) A multicenter, randomized, placebo‐controlled trial of atorvastatin for the primary prevention of cardiovascular events in patients with rheumatoid arthritis. Arthritis and Rheumatology, 71(9), pp. 1437-1449. (doi: 10.1002/art.40892) (PMID:30983166) (PMCID:PMC6771601)
Lyall, L. M., Cullen, B. , Lyall, D. M. , Leighton, S. P. , Siebert, S. , Smith, D. J. and Cavanagh, J. (2019) The associations between self-reported depression, self-reported chronic inflammatory conditions and cognitive abilities in UK Biobank. European Psychiatry, 60, pp. 63-70. (doi: 10.1016/j.eurpsy.2019.05.007) (PMID:31158611) (PMCID:PMC6669333)
Siebert, S. , Millar, N. L. and McInnes, I. B. (2019) Why did IL-23p19 inhibition fail in AS: a tale of tissues, trials or translation? Annals of the Rheumatic Diseases, 78(8), pp. 1015-1018. (doi: 10.1136/annrheumdis-2018-213654) (PMID:30297330) (PMCID:PMC6691857)
Derakhshan, M. H., Goodson, N. J., Packham, J. C., Sengupta, R., Molto, A., Marzo-Ortega, H. and Siebert, S. (2019) Increased risk of hypertension associated with spondyloarthritis disease duration: results from the ASAS-COMOSPA study. Journal of Rheumatology, 46(7), pp. 701-709. (doi: 10.3899/jrheum.180538) (PMID:30647169)
Abraham, S. et al. (2019) Advancing research paradigms and pathophysiological pathways in psoriatic arthritis and ankylosing spondylitis: Proceedings of the 2017 Platform for the Exchange of Expertise and Research (PEER) meeting. Seminars in Arthritis and Rheumatism, 48(6), pp. 1005-1013. (doi: 10.1016/j.semarthrit.2018.10.008) (PMID:30415944)
Robinson, P. C., Sengupta, R. and Siebert, S. (2019) Non-radiographic axial spondyloarthritis (nr-axSpA): advances in classification, imaging and therapy. Rheumatology and Therapy, 6(2), pp. 165-177. (doi: 10.1007/s40744-019-0146-6) (PMID:30788779) (PMCID:PMC6514020)
Macfarlane, G. J. et al. (2019) AxSpA patients who also meet criteria for fibromyalgia: identifying distinct patient clusters using data from a UK national register (BSRBR-AS). BMC Rheumatology, 3, 19. (doi: 10.1186/s41927-019-0066-7) (PMID:31143851) (PMCID:PMC6532149)
Derakhshan, M. H., Goodson, N. J., Packham, J., Sengupta, R., Molto, A., Marzo-Ortega, H., Siebert, S. and BRITSpA and the ASAS-COMOSPA Investigators, (2019) Association of diverticulitis with prolonged spondyloarthritis: an analysis of the ASAS-COMOSPA international cohort. Journal of Clinical Medicine, 8(3), 281. (doi: 10.3390/jcm8030281) (PMID:30813544)
Millar, N. L. , Siebert, S. and McInnes, I. B. (2019) Europe rules on harm from fluoroquinolone antibiotics. Nature, 566(7744), p. 326. (doi: 10.1038/d41586-019-00619-7) (PMID:30783286)
Fragoulis, G. E., McInnes, I. B. and Siebert, S. (2019) JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis. Rheumatology, 58(Supple), i43-i54. (doi: 10.1093/rheumatology/key276) (PMID:30806709) (PMCID:PMC6390879)
McDonald, M.T., Siebert, S. , Coulter, E.H. , McDonald, D.A. and Paul, L. (2019) Level of adherence to prescribed exercise in spondyloarthritis and factors affecting this adherence: a systematic review. Rheumatology International, 39(2), pp. 187-201. (doi: 10.1007/s00296-018-4225-8) (PMID:30649569) (PMCID:PMC6513902)
Nerurkar, L., Siebert, S. , McInnes, I. B. and Cavanagh, J. (2019) Rheumatoid arthritis and depression: an inflammatory perspective. Lancet Psychiatry, 6(2), pp. 164-173. (doi: 10.1016/S2215-0366(18)30255-4) (PMID:30366684)
Budu-Aggrey, A. et al. (2019) Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study. PLoS Medicine, 16(1), e1002739. (doi: 10.1371/journal.pmed.1002739) (PMID:30703100) (PMCID:PMC6354959)
Martin, K. R. et al. (2019) Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT). BMJ Open, 9(1), e026793. (doi: 10.1136/bmjopen-2018-026793) (PMID:30705244) (PMCID:PMC6359876)
Alvarez-Madrazo, S., Kavanagh, K., Siebert, S. , Semple, Y., Godman, B., Maciel Almeida, A., Acurcio, F. d. A. and Bennie, M. (2019) Discontinuation, persistence and adherence to subcutaneous biologics delivered via a homecare route to Scottish adults with rheumatic diseases: a retrospective study. BMJ Open, 9, e027059. (doi: 10.1136/bmjopen-2018-027059) (PMID:31488467)
Ferguson, L. D. , Siebert, S. , McInnes, I. B. and Sattar, N. (2019) Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions. Nature Reviews Rheumatology, 15, pp. 461-474. (doi: 10.1038/s41584-019-0256-0) (PMID:31292564)
2018
McInnes, I. B. and Siebert, S. (2018) The extending scope of kinase inhibition in immune diseases. Lancet, 392(10162), pp. 2328-2331. (doi: 10.1016/S0140-6736(18)32600-X) (PMID:30360966)
Macfarlane, G. J. et al. (2018) Influence of co-morbid fibromyalgia on disease activity measures and response to tumour necrosis factor inhibitors in axial spondyloarthritis: results from a UK national register. Rheumatology, 57(11), pp. 1982-1990. (doi: 10.1093/rheumatology/key206) (PMID:30053166) (PMCID:PMC6199528)
Fragoulis, G. E., Paterson, C., Gilmour, A., Derakhshan, M. H., McInnes, I. B. , Porter, D. and Siebert, S. (2018) Neutropaenia in early rheumatoid arthritis: frequency, predicting factors, natural history and outcome. RMD Open, 4(2), e000739. (doi: 10.1136/rmdopen-2018-000739) (PMID:30402267) (PMCID:PMC6203094)
Derakhshan, M. H., Pathak, H., Cook, D., Dickinson, S., Siebert, S. and Gaffney, K. (2018) Services for spondyloarthitis: a survey of patients and rheumatologists. Rheumatology, 57(6), pp. 987-996. (doi: 10.1093/rheumatology/kex518) (PMID:29529295)
Packham, J. C. et al. (2018) A new era for collaboration? Rheumatology, 57(5), pp. 775-776. (doi: 10.1093/rheumatology/kex083) (PMID:28407115)
Tecklenborg, J., Clayton, D., Siebert, S. and Coley, S. (2018) The role of the immune system in kidney disease. Clinical and Experimental Immunology, 192(2), pp. 142-150. (doi: 10.1111/cei.13119) (PMID:29453850)
2017
Pollock, J., Raza, K., Pratt, A. G., Hanson, H., Siebert, S. , Filer, A., Isaacs, J. D., Buckley, C. D., McInnes, I. B. and Falahee, M. (2017) Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research. Musculoskeletal Care, 15(4), pp. 395-399. (doi: 10.1002/msc.1171) (PMID:27982541) (PMCID:PMC5808150)
Macfarlane, G. J., Barnish, M. S., Pathan, E., Martin, K. R., Haywood, K. L., Siebert, S. , Packham, J., Atzeni, F. and Jones, G. T. (2017) The co-occurrence and characteristics of patients with axial spondyloarthritis who meet criteria for fibromyalgia: results from a UK national register (BSRBR-AS). Arthritis and Rheumatology, 69(11), pp. 2144-2150. (doi: 10.1002/art.40185) (PMID:28622461)
McInnes, I. B. , Porter, D. and Siebert, S. (2017) Editorial: choosing new targets for rheumatoid arthritis therapeutics: too interesting to fail? Arthritis and Rheumatology, 69(6), pp. 1131-1134. (doi: 10.1002/art.40082) (PMID:28245351)
Hamilton, L. et al. (2017) BSR and BHPR guideline for the treatment of axial spondyloarthritis (including ankylosing spondylitis) with biologics. Rheumatology, 56(2), pp. 313-316. (doi: 10.1093/rheumatology/kew223) (PMID:27558584)
Siebert, S. , Porter, D., Paterson, C., Hampson, R., Gaya, D., Latosinska, A., Mischak, H., Schanstra, J., Mullen, W. and McInnes, I. (2017) Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups. Scientific Reports, 7, 40473. (doi: 10.1038/srep40473) (PMID:28091549) (PMCID:PMC5320079)
2016
Dale, J. et al. (2016) The Scottish Early Rheumatoid Arthritis (SERA) Study: an inception cohort and biobank. BMC Musculoskeletal Disorders, 17, 461. (doi: 10.1186/s12891-016-1318-y) (PMID:27829394) (PMCID:PMC5103386)
Siebert, S. , Sengupta, R. and Tsoukas, A. (Eds.) (2016) Axial Spondyloarthritis. Series: Oxford rheumatology library. Oxford University Press. ISBN 9780198755296
Paul, L., Coulter, E.H. , Cameron, S., McDonald, M.T., Brandon, M., Cook, D., McConnachie, A. and Siebert, S. (2016) Web-based physiotherapy for people with axial spondyloarthritis (WEBPASS) – a study protocol. BMC Musculoskeletal Disorders, 17, 360. (doi: 10.1186/s12891-016-1218-1) (PMID:27553492) (PMCID:PMC4995794)
Kronisch, C. et al. (2016) Brief report: predicting functional disability: one-year results from the Scottish Early Rheumatoid Arthritis inception cohort. Arthritis and Rheumatology, 68(7), pp. 1596-1602. (doi: 10.1002/art.39627) (PMID:26866516)
Zhou, S. et al. (2016) Defining disease phenotypes in primary care electronic health records by a machine learning approach: a case study in identifying rheumatoid arthritis. PLoS ONE, 11(5), e0154515. (doi: 10.1371/journal.pone.0154515) (PMID:27135409) (PMCID:PMC4852928)
Wright, P. B., McEntegart, A., McCarey, D., McInnes, I. B. , Siebert, S. and Milling, S. W. F. (2016) Ankylosing Spondylitis patients display altered dendritic cell and T cell populations that implicate pathogenic roles for the IL-23 cytokine axis and intestinal inflammation. Rheumatology, 55(1), pp. 120-132. (doi: 10.1093/rheumatology/kev245) (PMID:26320138) (PMCID:PMC4676904)
Fragoulis, G. E., Siebert, S. and McInnes, I. B. (2016) Therapeutic targeting of IL-17 and IL-23 cytokines in immune-mediated diseases. Annual Review of Medicine, 67(1), pp. 337-353. (doi: 10.1146/annurev-med-051914-021944) (PMID:26565676)
Siebert, S. , Lyall, D. M. , Mackay, D. F. , Porter, D. and McInnes, I. B. (2016) Characteristics of rheumatoid arthritis and its association with major comorbid conditions: cross-sectional study of 502 649 UK Biobank participants. RMD Open, 2(1), e000267. (doi: 10.1136/rmdopen-2016-000267) (PMID:27403335) (PMCID:PMC4932291)
2015
Cooksey, R., Brophy, S., Dennis, M., Davies, H., Atkinson, M., Irvine, E. and Siebert, S. (2015) Severe flare as a predictor of poor outcome in ankylosing spondylitis: a cohort study using questionnaire and routine data linkage. Rheumatology, 54(9), pp. 1563-1572. (doi: 10.1093/rheumatology/kev015) (PMID:25802399)
Cooksey, R., Husain, M. J., Brophy, S., Davies, H., Rahman, M. A., Atkinson, M. D., Phillips, C. J. and Siebert, S. (2015) The cost of ankylosing spondylitis in the UK using linked routine and patient-reported survey data. PLoS ONE, 10(7), e0126105. (doi: 10.1371/journal.pone.0126105) (PMID:26185984) (PMCID:PMC4506082)
Wailoo, A., Hernández, M., Philips, C., Brophy, S. and Siebert, S. (2015) Modeling health state utility values in Ankylosing Spondylitis: comparisons of direct and indirect methods. Value in Health, 18(4), pp. 425-431. (doi: 10.1016/j.jval.2015.02.016) (PMID:26091596)
Siebert, S. , Tsoukas, A., Robertson, J. and McInnes, I. (2015) Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases. Pharmacological Reviews, 67(2), pp. 280-309. (doi: 10.1124/pr.114.009639) (PMID:25697599)
2014
McInnes, I. B. and Siebert, S. (2014) Psoriatic arthritis - expanding options, exciting times? Acta Reumatologica Portuguesa, 39(4), pp. 294-295.
Patterson, H., Nibbs, R. , McInnes, I. and Siebert, S. (2014) Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases. Clinical and Experimental Immunology, 176(1), pp. 1-10. (doi: 10.1111/cei.12248)
Frleta, M., Siebert, S. and McInnes, I. B. (2014) The interleukin-17 pathway in psoriasis and psoriatic arthritis: disease pathogenesis and possibilities of treatment. Current Rheumatology Reports, 16(414), (doi: 10.1007/s11926-014-0414-y) (PMID:24570394)
Orbai, A.-M. et al. (2014) Systematic review of treatment effectiveness and outcome measures for enthesitis in psoriatic arthritis. Journal of Rheumatology, 41(11), pp. 2290-2294. (doi: 10.3899/jrheum.140878)
2013
Brophy, S., Cooksey, R., Davies, H., Dennis, M.H., Zhou, S.M. and Siebert, S. (2013) The effect of physical activity and motivation on function in ankylosing spondylitis: a cohort study. Seminars in Arthritis and Rheumatism, 42(6), pp. 619-626. (doi: 10.1016/j.semarthrit.2012.09.007)
Brophy, S., Davies, H., Dennis, M.S., Cooksey, R., Husain, M.J., Irvine, E. and Siebert, S. (2013) Fatigue in ankylosing spondylitis: treatment should focus on pain management. Seminars in Arthritis and Rheumatism, 42(4), pp. 361-367. (doi: 10.1016/j.semarthrit.2012.06.002)
Davies, H., Brophy, S., Dennis, M., Cooksey, R., Irvine, E. and Siebert, S. (2013) Patient perspectives of managing fatigue in ankylosing spondylitis, and views on potential interventions: a qualitative study. BMC Musculoskeletal Disorders, 14(163), (doi: 10.1186/1471-2474-14-163)
Evans, B.A. et al. (2013) Involving service users in trials: developing a standard operating procedure. Trials, 14(219), (doi: 10.1186/1745-6215-14-219)
Nijjar, J., Tindell, A., McInnes, I.B. and Siebert, S. (2013) Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis. Rheumatology, 52(9), pp. 1556-1562. (doi: 10.1093/rheumatology/ket225) (PMID:23861534)
Rapport, F. et al. (2013) Qualitative research within trials: developing a standard operating procedure for a clinical trials unit. Trials, 14(54), (doi: 10.1186/1745-6215-14-54)
2012
Brophy, S., Cooksey, R., Atkinson, M., Zhou, S., Husain, M.J., Macey, S., Rahman, M.A. and Siebert, S. (2012) No increased rate of acute myocardial infarction or stroke among patients with ankylosing spondylitis—a retrospective cohort study using routine data. Seminars in Arthritis and Rheumatism, 42(2), pp. 140-145. (doi: 10.1016/j.semarthrit.2012.02.008)
Cooksey, R., Brophy, S., Husain, M.J., Irvine, E., Davies, H. and Siebert, S. (2012) The information needs of people living with ankylosing spondylitis: a questionnaire survey. BMC Musculoskeletal Disorders, 13(243), (doi: 10.1186/1471-2474-13-243)
Husain, M.J., Brophy, S., Macey, S., Pinder, L.M., Atkinson, M.D., Cooksey, R., Phillips, C.J. and Siebert, S. (2012) HERALD (Health Economics using Routine Anonymised Linked Data). BMC Medical Informatics and Decision Making, 12(1), p. 24. (doi: 10.1186/1472-6947-12-24)
2010
Atkinson, M. D., Brophy, S., Siebert, S. , Gravenor, M. B., Phillips, C. J., Ford, D. V., Jones, K. H. and Lyons, R. A. (2010) Protocol for a population-based Ankylosing Spondylitis (PAS) cohort in Wales. BMC Musculoskeletal Disorders, 11(1), 197. (doi: 10.1186/1471-2474-11-197) (PMID:20809952) (PMCID:PMC2941484)
Cooksey, R., Brophy, S., Gravenor, M.B., Brooks, C.J., Burrows, C.L. and Siebert, S. (2010) Frequency and characteristics of disease flares in ankylosing spondylitis. Rheumatology, 49(5), pp. 929-932. (doi: 10.1093/rheumatology/kep435)
2008
Siebert, S. , Amos, N. and Lawson, T. M. (2008) Comment on: Failure of anti-TNF therapy in TNF receptor 1-associated periodic syndrome (TRAPS). Rheumatology, 47(2), pp. 228-229. (doi: 10.1093/rheumatology/kem243) (PMID:18056150)
Brophy, S., Burrows, C.L., Brooks, C., Gravenor, M.B., Siebert, S. and Allen, S.J. (2008) Internet-based randomised controlled trials for the evaluation of complementary and alternative medicines: probiotics in spondyloarthropathy. BMC Musculoskeletal Disorders, 9(1), p. 4. (doi: 10.1186/1471-2474-9-4)
2007
Siebert, S. , Amos, N., Williams, B. D. and Lawson, T. M. (2007) Cytokine production by hepatic anaplastic large-cell lymphoma presenting as a rheumatic syndrome. Seminars in Arthritis and Rheumatism, 37(1), pp. 63-67. (doi: 10.1016/j.semarthrit.2006.12.007) (PMID:17363040)
Evans, S.J., Webb, D., Lawson, T. M. and Siebert, S. (2007) Renal tubular acidosis associated with leflunomide. Rheumatology, 46(6), p. 1040. (doi: 10.1093/rheumatology/kem044) (PMID:17409131)
2005
Siebert, S. , Fielding, C. A., Williams, B. D. and Brennan, P. (2005) Mutation of the extracellular domain of tumour necrosis factor receptor 1 causes reduced NF-κB activation due to decreased surface expression. FEBS Letters, 579(23), pp. 5193-5198. (doi: 10.1016/j.febslet.2005.08.037) (PMID:16162344)
Siebert, S. , Amos, N., Fielding, C. A., Wang, E. C. Y., Aksentijevich, I., Williams, B. D. and Brennan, P. (2005) Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant. Arthritis and Rheumatism, 52(4), pp. 1287-1292. (doi: 10.1002/art.20955) (PMID:15818692) (PMCID:PMC2842000)
2004
Fielding, C. A., Siebert, S. , Rowe, M. and Brennan, P. (2004) Analysis of human tumour necrosis factor receptor 1 dominant-negative mutants reveals a major region controlling cell surface expression. FEBS Letters, 570(1-3), pp. 138-142. (doi: 10.1016/j.febslet.2004.06.035) (PMID:15251454)
Siebert, S. and Srinivasan, U. (2004) Proptosis can be the presenting feature of systemic lupus erythematosus. Annals of the Rheumatic Diseases, 63(8), pp. 908-909. (doi: 10.1136/ard.2004.020602) (PMID:15249316) (PMCID:PMC1755100)
2003
Siebert, S. , Williams, B. D., Henley, R., Ellis, R., Cavill, I. and Worwood, M. (2003) Single value of serum transferrin receptor is not diagnostic for the absence of iron stores in anaemic patients with rheumatoid arthritis. Clinical and Laboratory Haematology, 25(3), pp. 155-160. (doi: 10.1046/j.1365-2257.2003.00509.x) (PMID:12755791)
2001
Lawson, T.M., Siebert, S. and Williams, B.D. (2001) Clinical images: Brown's syndrome: an unusual case of diplopia in rheumatoid arthritis. Arthritis and Rheumatism, 44(10), p. 2460. (doi: 10.1002/1529-0131(200110)44:10<2460::AID-ART422>3.0.CO;2-S) (PMID:11665995)
Siebert, S. , Lawson, T.M., Wheeler, M.H., Martin, J.C. and Williams, B.D. (2001) Polymyalgia rheumatica: pitfalls in diagnosis. Journal of the Royal Society of Medicine, 94(5), pp. 242-244. (doi: 10.1177/014107680109400513) (PMID:11385095) (PMCID:PMC1281460)
Articles
Colton, H. et al. (2024) Greater preservation of SARS‐CoV‐2 neutralising antibody responses following the ChAdOx1‐S (AZD1222) vaccine compared with mRNA vaccines in haematopoietic cell transplant recipients. British Journal of Haematology, (doi: 10.1111/bjh.19874) (PMID:39551718) (Early Online Publication)
Siebert, S. , Schett, G., Raychaudhuri, S. P., Guma, M., Chen, W., Gao, S., Chakravarty, S. D., Lavie, F. and Rahman, P. (2024) Correlation of changes in inflammatory and collagen biomarkers with durable guselkumab Efficacy through 2 years in participants with active psoriatic arthritis: results from a phase III randomized controlled trial. Therapeutic Advances in Musculoskeletal Disease, 16, 1759720X241283536. (doi: 10.1177/1759720X241283536)
Gray, S. R. , Montoye, A. H.K., Vondrasek, J. D., Neph, S., Siebert, S. , Paul, L., Bachmair, E. M. and Basu, N. (2024) Associations of physical activity levels with fatigue in people with inflammatory rheumatic disease in the LIFT trial. Rheumatology Advances in Practice, (Accepted for Publication)
Siebert, S. et al. (2024) Modulation of IL‐23 signaling with guselkumab in biologic‐naïve patients versus TNF inhibitor‐inadequate responders with active psoriatic arthritis. Arthritis and Rheumatology, 76(6), pp. 894-904. (doi: 10.1002/art.42803) (PMID:38253404)
Goodyear, C. S. et al. (2024) Immunogenicity of third dose COVID-19 vaccine strategies in patients who are immunocompromised with suboptimal immunity following two doses (OCTAVE-DUO): an open-label, multicentre, randomised, controlled, phase 3 trial. Lancet Rheumatology, 6(6), e339-e351. (doi: 10.1016/S2665-9913(24)00065-1) (PMID:38734019)
Vassilakis, K. D., Magiouf, K., Siebert, S. and Fragoulis, G. E. (2024) Selective JAK-inhibitors in spondyloarthritis. Mediterranean Journal of Rheumatology, 35(Suppl1), pp. 27-36. (doi: 10.31138/mjr.311023.sji) (PMID:38756935) (PMCID:PMC11094441)
Coates, L. C. et al. (2024) Enhancing current guidance for psoriatic arthritis and its comorbidities: recommendations from an expert consensus panel. Rheumatology, (doi: 10.1093/rheumatology/keae172) (PMID:38490262) (Early Online Publication)
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Lyall, L. M., Cullen, B. , Lyall, D. M. , Leighton, S. P. , Siebert, S. , Smith, D. J. and Cavanagh, J. (2019) The associations between self-reported depression, self-reported chronic inflammatory conditions and cognitive abilities in UK Biobank. European Psychiatry, 60, pp. 63-70. (doi: 10.1016/j.eurpsy.2019.05.007) (PMID:31158611) (PMCID:PMC6669333)
Siebert, S. , Millar, N. L. and McInnes, I. B. (2019) Why did IL-23p19 inhibition fail in AS: a tale of tissues, trials or translation? Annals of the Rheumatic Diseases, 78(8), pp. 1015-1018. (doi: 10.1136/annrheumdis-2018-213654) (PMID:30297330) (PMCID:PMC6691857)
Derakhshan, M. H., Goodson, N. J., Packham, J. C., Sengupta, R., Molto, A., Marzo-Ortega, H. and Siebert, S. (2019) Increased risk of hypertension associated with spondyloarthritis disease duration: results from the ASAS-COMOSPA study. Journal of Rheumatology, 46(7), pp. 701-709. (doi: 10.3899/jrheum.180538) (PMID:30647169)
Abraham, S. et al. (2019) Advancing research paradigms and pathophysiological pathways in psoriatic arthritis and ankylosing spondylitis: Proceedings of the 2017 Platform for the Exchange of Expertise and Research (PEER) meeting. Seminars in Arthritis and Rheumatism, 48(6), pp. 1005-1013. (doi: 10.1016/j.semarthrit.2018.10.008) (PMID:30415944)
Robinson, P. C., Sengupta, R. and Siebert, S. (2019) Non-radiographic axial spondyloarthritis (nr-axSpA): advances in classification, imaging and therapy. Rheumatology and Therapy, 6(2), pp. 165-177. (doi: 10.1007/s40744-019-0146-6) (PMID:30788779) (PMCID:PMC6514020)
Macfarlane, G. J. et al. (2019) AxSpA patients who also meet criteria for fibromyalgia: identifying distinct patient clusters using data from a UK national register (BSRBR-AS). BMC Rheumatology, 3, 19. (doi: 10.1186/s41927-019-0066-7) (PMID:31143851) (PMCID:PMC6532149)
Derakhshan, M. H., Goodson, N. J., Packham, J., Sengupta, R., Molto, A., Marzo-Ortega, H., Siebert, S. and BRITSpA and the ASAS-COMOSPA Investigators, (2019) Association of diverticulitis with prolonged spondyloarthritis: an analysis of the ASAS-COMOSPA international cohort. Journal of Clinical Medicine, 8(3), 281. (doi: 10.3390/jcm8030281) (PMID:30813544)
Millar, N. L. , Siebert, S. and McInnes, I. B. (2019) Europe rules on harm from fluoroquinolone antibiotics. Nature, 566(7744), p. 326. (doi: 10.1038/d41586-019-00619-7) (PMID:30783286)
Fragoulis, G. E., McInnes, I. B. and Siebert, S. (2019) JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis. Rheumatology, 58(Supple), i43-i54. (doi: 10.1093/rheumatology/key276) (PMID:30806709) (PMCID:PMC6390879)
McDonald, M.T., Siebert, S. , Coulter, E.H. , McDonald, D.A. and Paul, L. (2019) Level of adherence to prescribed exercise in spondyloarthritis and factors affecting this adherence: a systematic review. Rheumatology International, 39(2), pp. 187-201. (doi: 10.1007/s00296-018-4225-8) (PMID:30649569) (PMCID:PMC6513902)
Nerurkar, L., Siebert, S. , McInnes, I. B. and Cavanagh, J. (2019) Rheumatoid arthritis and depression: an inflammatory perspective. Lancet Psychiatry, 6(2), pp. 164-173. (doi: 10.1016/S2215-0366(18)30255-4) (PMID:30366684)
Budu-Aggrey, A. et al. (2019) Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study. PLoS Medicine, 16(1), e1002739. (doi: 10.1371/journal.pmed.1002739) (PMID:30703100) (PMCID:PMC6354959)
Martin, K. R. et al. (2019) Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT). BMJ Open, 9(1), e026793. (doi: 10.1136/bmjopen-2018-026793) (PMID:30705244) (PMCID:PMC6359876)
Alvarez-Madrazo, S., Kavanagh, K., Siebert, S. , Semple, Y., Godman, B., Maciel Almeida, A., Acurcio, F. d. A. and Bennie, M. (2019) Discontinuation, persistence and adherence to subcutaneous biologics delivered via a homecare route to Scottish adults with rheumatic diseases: a retrospective study. BMJ Open, 9, e027059. (doi: 10.1136/bmjopen-2018-027059) (PMID:31488467)
Ferguson, L. D. , Siebert, S. , McInnes, I. B. and Sattar, N. (2019) Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions. Nature Reviews Rheumatology, 15, pp. 461-474. (doi: 10.1038/s41584-019-0256-0) (PMID:31292564)
McInnes, I. B. and Siebert, S. (2018) The extending scope of kinase inhibition in immune diseases. Lancet, 392(10162), pp. 2328-2331. (doi: 10.1016/S0140-6736(18)32600-X) (PMID:30360966)
Macfarlane, G. J. et al. (2018) Influence of co-morbid fibromyalgia on disease activity measures and response to tumour necrosis factor inhibitors in axial spondyloarthritis: results from a UK national register. Rheumatology, 57(11), pp. 1982-1990. (doi: 10.1093/rheumatology/key206) (PMID:30053166) (PMCID:PMC6199528)
Fragoulis, G. E., Paterson, C., Gilmour, A., Derakhshan, M. H., McInnes, I. B. , Porter, D. and Siebert, S. (2018) Neutropaenia in early rheumatoid arthritis: frequency, predicting factors, natural history and outcome. RMD Open, 4(2), e000739. (doi: 10.1136/rmdopen-2018-000739) (PMID:30402267) (PMCID:PMC6203094)
Derakhshan, M. H., Pathak, H., Cook, D., Dickinson, S., Siebert, S. and Gaffney, K. (2018) Services for spondyloarthitis: a survey of patients and rheumatologists. Rheumatology, 57(6), pp. 987-996. (doi: 10.1093/rheumatology/kex518) (PMID:29529295)
Packham, J. C. et al. (2018) A new era for collaboration? Rheumatology, 57(5), pp. 775-776. (doi: 10.1093/rheumatology/kex083) (PMID:28407115)
Tecklenborg, J., Clayton, D., Siebert, S. and Coley, S. (2018) The role of the immune system in kidney disease. Clinical and Experimental Immunology, 192(2), pp. 142-150. (doi: 10.1111/cei.13119) (PMID:29453850)
Pollock, J., Raza, K., Pratt, A. G., Hanson, H., Siebert, S. , Filer, A., Isaacs, J. D., Buckley, C. D., McInnes, I. B. and Falahee, M. (2017) Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research. Musculoskeletal Care, 15(4), pp. 395-399. (doi: 10.1002/msc.1171) (PMID:27982541) (PMCID:PMC5808150)
Macfarlane, G. J., Barnish, M. S., Pathan, E., Martin, K. R., Haywood, K. L., Siebert, S. , Packham, J., Atzeni, F. and Jones, G. T. (2017) The co-occurrence and characteristics of patients with axial spondyloarthritis who meet criteria for fibromyalgia: results from a UK national register (BSRBR-AS). Arthritis and Rheumatology, 69(11), pp. 2144-2150. (doi: 10.1002/art.40185) (PMID:28622461)
McInnes, I. B. , Porter, D. and Siebert, S. (2017) Editorial: choosing new targets for rheumatoid arthritis therapeutics: too interesting to fail? Arthritis and Rheumatology, 69(6), pp. 1131-1134. (doi: 10.1002/art.40082) (PMID:28245351)
Hamilton, L. et al. (2017) BSR and BHPR guideline for the treatment of axial spondyloarthritis (including ankylosing spondylitis) with biologics. Rheumatology, 56(2), pp. 313-316. (doi: 10.1093/rheumatology/kew223) (PMID:27558584)
Siebert, S. , Porter, D., Paterson, C., Hampson, R., Gaya, D., Latosinska, A., Mischak, H., Schanstra, J., Mullen, W. and McInnes, I. (2017) Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups. Scientific Reports, 7, 40473. (doi: 10.1038/srep40473) (PMID:28091549) (PMCID:PMC5320079)
Dale, J. et al. (2016) The Scottish Early Rheumatoid Arthritis (SERA) Study: an inception cohort and biobank. BMC Musculoskeletal Disorders, 17, 461. (doi: 10.1186/s12891-016-1318-y) (PMID:27829394) (PMCID:PMC5103386)
Paul, L., Coulter, E.H. , Cameron, S., McDonald, M.T., Brandon, M., Cook, D., McConnachie, A. and Siebert, S. (2016) Web-based physiotherapy for people with axial spondyloarthritis (WEBPASS) – a study protocol. BMC Musculoskeletal Disorders, 17, 360. (doi: 10.1186/s12891-016-1218-1) (PMID:27553492) (PMCID:PMC4995794)
Kronisch, C. et al. (2016) Brief report: predicting functional disability: one-year results from the Scottish Early Rheumatoid Arthritis inception cohort. Arthritis and Rheumatology, 68(7), pp. 1596-1602. (doi: 10.1002/art.39627) (PMID:26866516)
Zhou, S. et al. (2016) Defining disease phenotypes in primary care electronic health records by a machine learning approach: a case study in identifying rheumatoid arthritis. PLoS ONE, 11(5), e0154515. (doi: 10.1371/journal.pone.0154515) (PMID:27135409) (PMCID:PMC4852928)
Wright, P. B., McEntegart, A., McCarey, D., McInnes, I. B. , Siebert, S. and Milling, S. W. F. (2016) Ankylosing Spondylitis patients display altered dendritic cell and T cell populations that implicate pathogenic roles for the IL-23 cytokine axis and intestinal inflammation. Rheumatology, 55(1), pp. 120-132. (doi: 10.1093/rheumatology/kev245) (PMID:26320138) (PMCID:PMC4676904)
Fragoulis, G. E., Siebert, S. and McInnes, I. B. (2016) Therapeutic targeting of IL-17 and IL-23 cytokines in immune-mediated diseases. Annual Review of Medicine, 67(1), pp. 337-353. (doi: 10.1146/annurev-med-051914-021944) (PMID:26565676)
Siebert, S. , Lyall, D. M. , Mackay, D. F. , Porter, D. and McInnes, I. B. (2016) Characteristics of rheumatoid arthritis and its association with major comorbid conditions: cross-sectional study of 502 649 UK Biobank participants. RMD Open, 2(1), e000267. (doi: 10.1136/rmdopen-2016-000267) (PMID:27403335) (PMCID:PMC4932291)
Cooksey, R., Brophy, S., Dennis, M., Davies, H., Atkinson, M., Irvine, E. and Siebert, S. (2015) Severe flare as a predictor of poor outcome in ankylosing spondylitis: a cohort study using questionnaire and routine data linkage. Rheumatology, 54(9), pp. 1563-1572. (doi: 10.1093/rheumatology/kev015) (PMID:25802399)
Cooksey, R., Husain, M. J., Brophy, S., Davies, H., Rahman, M. A., Atkinson, M. D., Phillips, C. J. and Siebert, S. (2015) The cost of ankylosing spondylitis in the UK using linked routine and patient-reported survey data. PLoS ONE, 10(7), e0126105. (doi: 10.1371/journal.pone.0126105) (PMID:26185984) (PMCID:PMC4506082)
Wailoo, A., Hernández, M., Philips, C., Brophy, S. and Siebert, S. (2015) Modeling health state utility values in Ankylosing Spondylitis: comparisons of direct and indirect methods. Value in Health, 18(4), pp. 425-431. (doi: 10.1016/j.jval.2015.02.016) (PMID:26091596)
Siebert, S. , Tsoukas, A., Robertson, J. and McInnes, I. (2015) Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases. Pharmacological Reviews, 67(2), pp. 280-309. (doi: 10.1124/pr.114.009639) (PMID:25697599)
McInnes, I. B. and Siebert, S. (2014) Psoriatic arthritis - expanding options, exciting times? Acta Reumatologica Portuguesa, 39(4), pp. 294-295.
Patterson, H., Nibbs, R. , McInnes, I. and Siebert, S. (2014) Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases. Clinical and Experimental Immunology, 176(1), pp. 1-10. (doi: 10.1111/cei.12248)
Frleta, M., Siebert, S. and McInnes, I. B. (2014) The interleukin-17 pathway in psoriasis and psoriatic arthritis: disease pathogenesis and possibilities of treatment. Current Rheumatology Reports, 16(414), (doi: 10.1007/s11926-014-0414-y) (PMID:24570394)
Orbai, A.-M. et al. (2014) Systematic review of treatment effectiveness and outcome measures for enthesitis in psoriatic arthritis. Journal of Rheumatology, 41(11), pp. 2290-2294. (doi: 10.3899/jrheum.140878)
Brophy, S., Cooksey, R., Davies, H., Dennis, M.H., Zhou, S.M. and Siebert, S. (2013) The effect of physical activity and motivation on function in ankylosing spondylitis: a cohort study. Seminars in Arthritis and Rheumatism, 42(6), pp. 619-626. (doi: 10.1016/j.semarthrit.2012.09.007)
Brophy, S., Davies, H., Dennis, M.S., Cooksey, R., Husain, M.J., Irvine, E. and Siebert, S. (2013) Fatigue in ankylosing spondylitis: treatment should focus on pain management. Seminars in Arthritis and Rheumatism, 42(4), pp. 361-367. (doi: 10.1016/j.semarthrit.2012.06.002)
Davies, H., Brophy, S., Dennis, M., Cooksey, R., Irvine, E. and Siebert, S. (2013) Patient perspectives of managing fatigue in ankylosing spondylitis, and views on potential interventions: a qualitative study. BMC Musculoskeletal Disorders, 14(163), (doi: 10.1186/1471-2474-14-163)
Evans, B.A. et al. (2013) Involving service users in trials: developing a standard operating procedure. Trials, 14(219), (doi: 10.1186/1745-6215-14-219)
Nijjar, J., Tindell, A., McInnes, I.B. and Siebert, S. (2013) Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis. Rheumatology, 52(9), pp. 1556-1562. (doi: 10.1093/rheumatology/ket225) (PMID:23861534)
Rapport, F. et al. (2013) Qualitative research within trials: developing a standard operating procedure for a clinical trials unit. Trials, 14(54), (doi: 10.1186/1745-6215-14-54)
Brophy, S., Cooksey, R., Atkinson, M., Zhou, S., Husain, M.J., Macey, S., Rahman, M.A. and Siebert, S. (2012) No increased rate of acute myocardial infarction or stroke among patients with ankylosing spondylitis—a retrospective cohort study using routine data. Seminars in Arthritis and Rheumatism, 42(2), pp. 140-145. (doi: 10.1016/j.semarthrit.2012.02.008)
Cooksey, R., Brophy, S., Husain, M.J., Irvine, E., Davies, H. and Siebert, S. (2012) The information needs of people living with ankylosing spondylitis: a questionnaire survey. BMC Musculoskeletal Disorders, 13(243), (doi: 10.1186/1471-2474-13-243)
Husain, M.J., Brophy, S., Macey, S., Pinder, L.M., Atkinson, M.D., Cooksey, R., Phillips, C.J. and Siebert, S. (2012) HERALD (Health Economics using Routine Anonymised Linked Data). BMC Medical Informatics and Decision Making, 12(1), p. 24. (doi: 10.1186/1472-6947-12-24)
Atkinson, M. D., Brophy, S., Siebert, S. , Gravenor, M. B., Phillips, C. J., Ford, D. V., Jones, K. H. and Lyons, R. A. (2010) Protocol for a population-based Ankylosing Spondylitis (PAS) cohort in Wales. BMC Musculoskeletal Disorders, 11(1), 197. (doi: 10.1186/1471-2474-11-197) (PMID:20809952) (PMCID:PMC2941484)
Cooksey, R., Brophy, S., Gravenor, M.B., Brooks, C.J., Burrows, C.L. and Siebert, S. (2010) Frequency and characteristics of disease flares in ankylosing spondylitis. Rheumatology, 49(5), pp. 929-932. (doi: 10.1093/rheumatology/kep435)
Siebert, S. , Amos, N. and Lawson, T. M. (2008) Comment on: Failure of anti-TNF therapy in TNF receptor 1-associated periodic syndrome (TRAPS). Rheumatology, 47(2), pp. 228-229. (doi: 10.1093/rheumatology/kem243) (PMID:18056150)
Brophy, S., Burrows, C.L., Brooks, C., Gravenor, M.B., Siebert, S. and Allen, S.J. (2008) Internet-based randomised controlled trials for the evaluation of complementary and alternative medicines: probiotics in spondyloarthropathy. BMC Musculoskeletal Disorders, 9(1), p. 4. (doi: 10.1186/1471-2474-9-4)
Siebert, S. , Amos, N., Williams, B. D. and Lawson, T. M. (2007) Cytokine production by hepatic anaplastic large-cell lymphoma presenting as a rheumatic syndrome. Seminars in Arthritis and Rheumatism, 37(1), pp. 63-67. (doi: 10.1016/j.semarthrit.2006.12.007) (PMID:17363040)
Evans, S.J., Webb, D., Lawson, T. M. and Siebert, S. (2007) Renal tubular acidosis associated with leflunomide. Rheumatology, 46(6), p. 1040. (doi: 10.1093/rheumatology/kem044) (PMID:17409131)
Siebert, S. , Fielding, C. A., Williams, B. D. and Brennan, P. (2005) Mutation of the extracellular domain of tumour necrosis factor receptor 1 causes reduced NF-κB activation due to decreased surface expression. FEBS Letters, 579(23), pp. 5193-5198. (doi: 10.1016/j.febslet.2005.08.037) (PMID:16162344)
Siebert, S. , Amos, N., Fielding, C. A., Wang, E. C. Y., Aksentijevich, I., Williams, B. D. and Brennan, P. (2005) Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant. Arthritis and Rheumatism, 52(4), pp. 1287-1292. (doi: 10.1002/art.20955) (PMID:15818692) (PMCID:PMC2842000)
Fielding, C. A., Siebert, S. , Rowe, M. and Brennan, P. (2004) Analysis of human tumour necrosis factor receptor 1 dominant-negative mutants reveals a major region controlling cell surface expression. FEBS Letters, 570(1-3), pp. 138-142. (doi: 10.1016/j.febslet.2004.06.035) (PMID:15251454)
Siebert, S. and Srinivasan, U. (2004) Proptosis can be the presenting feature of systemic lupus erythematosus. Annals of the Rheumatic Diseases, 63(8), pp. 908-909. (doi: 10.1136/ard.2004.020602) (PMID:15249316) (PMCID:PMC1755100)
Siebert, S. , Williams, B. D., Henley, R., Ellis, R., Cavill, I. and Worwood, M. (2003) Single value of serum transferrin receptor is not diagnostic for the absence of iron stores in anaemic patients with rheumatoid arthritis. Clinical and Laboratory Haematology, 25(3), pp. 155-160. (doi: 10.1046/j.1365-2257.2003.00509.x) (PMID:12755791)
Lawson, T.M., Siebert, S. and Williams, B.D. (2001) Clinical images: Brown's syndrome: an unusual case of diplopia in rheumatoid arthritis. Arthritis and Rheumatism, 44(10), p. 2460. (doi: 10.1002/1529-0131(200110)44:10<2460::AID-ART422>3.0.CO;2-S) (PMID:11665995)
Siebert, S. , Lawson, T.M., Wheeler, M.H., Martin, J.C. and Williams, B.D. (2001) Polymyalgia rheumatica: pitfalls in diagnosis. Journal of the Royal Society of Medicine, 94(5), pp. 242-244. (doi: 10.1177/014107680109400513) (PMID:11385095) (PMCID:PMC1281460)
Edited Books
Siebert, S. , Sengupta, R. and Tsoukas, A. (Eds.) (2016) Axial Spondyloarthritis. Series: Oxford rheumatology library. Oxford University Press. ISBN 9780198755296
Conference or Workshop Item
Derakhshan, M. H., Morton, F. , Fragoulis, G. E., Paterson, C., Dale, J., Basu, N. , Mcinnes, I., Porter, D. and Siebert, S. (2021) Opioids and analgesic use in early rheumatoid arthritis: a longitudinal analysis of linked real-world prescription data. Annals of the Rheumatic Diseases 80(S1): 1159. EULAR 2021 Virtual Congress., 2-5 June 2021. (doi: 10.1136/annrheumdis-2021-eular.2672)
Conference Proceedings
Ferguson, L. , Welsh, P. , Brown, R., Tindell, A., Kerrigan, S., Sattar, N. , McInnes, I. and Siebert, S. (2019) Effect of Phosphodiesterase 4 Inhibition with Apremilast on Cardiometabolic Outcomes in Psoriatic Arthritis – Initial Results from the Immune Metabolic Associations in Psoriatic Arthritis (IMAPA) Study. In: 2019 ACR/ARP Annual Meeting, Atlanta, GA, 8-13 November 2019,
Protocols
Gad Kilonzo, K. et al. (2023) Estimating the prevalence, quality of life, economic and societal impact of arthritis in Tanzania: protocol for a mixed methods study. [Protocols]
Gad Kilonzo, K. et al. (2023) Analysis of qualitative data, Statistical Analysis and Health Economic Analysis. [Protocols]
Gad Kilonzo, K. et al. (2023) Data storage and security. [Protocols]
Gad Kilonzo, K. et al. (2023) Laboratory and radiological data collection. [Protocols]
Kilonzo, K. G. et al. (2023) Community-based cross-sectional survey. [Protocols]
Kilonzo, K. G. et al. (2023) Estimating the prevalence, quality of life, economic and societal impact of arthritis in Tanzania: protocol for a mixed methods study. [Protocols]
Kilonzo, K. G. et al. (2023) Qualitative methods. [Protocols]
Research datasets
2022
Yongolo, N., Halliday, J. , Bunn, C. , Mtesha, B., Kelly, C., Krauth, S. , Mwingwa, A., Biswaro, S., Siebert, S. , Kipengele, A., Walker, R., McIntosh, E. and MMBAGA, B. T. (2022) Estimating prevalence and predictors of musculoskeletal disorders in Tanzania – A pilot study. [Data Collection]
