2023

van Dinther, M. et al. (2023) CD44 acts as a co-receptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic. Proceedings of the National Academy of Sciences of the United States of America, 120(34), e230237012. (doi: 10.1073/pnas.2302370120) (PMID:37590410) (PMCID:PMC10450677)

Singh, S. P. (2023) Regulation of the Scar/WAVE complex in migrating cells: a summary of our understanding. Journal of Biosciences, 48, 16. (doi: 10.1007/s12038-023-00341-7) (PMID:37204155)

Li, D. et al. (2023) GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3. Journal of Cell Biology, 222(6), e202208151. (doi: 10.1083/jcb.202208151) (PMID:37010470) (PMCID:PMC10072221)

2022

Singh, S. P. , Paschke, P., Tweedy, L. and Insall, R. H. (2022) AKT and SGK kinases regulate cell migration by altering Scar/WAVE complex activation and Arp2/3 complex recruitment. Frontiers in Molecular Biosciences, 9, 965921. (doi: 10.3389/fmolb.2022.965921) (PMID:36106016) (PMCID:PMC9466652)

Singh, S. P. and Insall, R. H. (2022) Under-agarose chemotaxis and migration assays for dictyostelium. In: Chang, C. and Wang, J. (eds.) Cell Polarity Signaling: Methods and Protocols. Series: Methods in Molecular Biology, 2438. Humana Press: New York, pp. 467-482. ISBN 9781071620342 (doi: 10.1007/978-1-0716-2035-9_27)

2021

Singh, S. P. , Thomason, P. A. and Insall, R. H. (2021) Extracellular signalling modulates Scar/WAVE complex activity through Abi phosphorylation. Cells, 10(12), 3485. (doi: 10.3390/cells10123485) (PMID:34943993) (PMCID:PMC8700165)

Yang, Y., Li, D., Chao, X., Singh, S. P. , Thomason, P., Yan, Y., Dong, M., Li, L., Insall, R. H. and Cai, H. (2021) Leep1 interacts with PIP3 and the Scar/WAVE complex to regulate cell migration and macropinocytosis. Journal of Cell Biology, 220(7), e202010096. (doi: 10.1083/jcb.202010096) (PMID:33978708) (PMCID:PMC8127007)

Dhakshinamoorthy, R. and Singh, S. P. (2021) Evolution of reproductive division of labor - lessons learned from the social amoeba Dictyostelium discoideum during its multicellular development. Frontiers in Cell and Developmental Biology, 9, 599525. (doi: 10.3389/fcell.2021.599525) (PMID:33748102) (PMCID:PMC7969725)

Singh, S. P. and Insall, R. H. (2021) Adhesion stimulates Scar/WAVE phosphorylation in mammalian cells. Communicative and Integrative Biology, 14(1), pp. 1-4. (doi: 10.1080/19420889.2020.1855854) (PMID:33447346) (PMCID:PMC7781634)

2020

Singh, S. P. , Thomason, P. A., Lilla, S., Schaks, M., Tang, Q., Goode, B. L., Machesky, L. M. , Rottner, K. and Insall, R. H. (2020) Cell–substrate adhesion drives Scar/WAVE activation and phosphorylation by a Ste20-family kinase, which controls pseudopod lifetime. PLoS Biology, 18(8), e3000774. (doi: 10.1371/journal.pbio.3000774) (PMID:32745097) (PMCID:PMC7425996)

2018

Schaks, M., Singh, S. P. , Kage, F., Thomason, P., Klünemann, T., Steffen, A., Blankenfeldt, W., Stradal, T. E., Insall, R. H. and Rottner, K. (2018) Distinct interaction sites of Rac GTPase with WAVE regulatory complex have non-redundant functions in vivo. Current Biology, 28(22), 3674-3684.e6. (doi: 10.1016/j.cub.2018.10.002) (PMID:30393033) (PMCID:PMC6264382)

2014

Singh, S. P. , Dhakshinamoorthy, R., Jaiswal, P., Schmidt, S., Thewes, S. and Baskar, R. (2014) The thyroxine inactivating gene, type III deiodinase, suppresses multiple signaling centers in Dictyostelium discoideum. Developmental Biology, 396(2), pp. 256-268. (doi: 10.1016/j.ydbio.2014.10.012) (PMID:25446527)

2012

Jaiswal, P., Singh, S. P. , Aiyar, P., Akkali, R. and Baskar, R. (2012) Regulation of multiple tip formation by caffeine in cellular slime molds. BMC Developmental Biology, 12, 26. (doi: 10.1186/1471-213x-12-26) (PMID:22928977) (PMCID:PMC3488011)

Articles

van Dinther, M. et al. (2023) CD44 acts as a co-receptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic. Proceedings of the National Academy of Sciences of the United States of America, 120(34), e230237012. (doi: 10.1073/pnas.2302370120) (PMID:37590410) (PMCID:PMC10450677)

Singh, S. P. (2023) Regulation of the Scar/WAVE complex in migrating cells: a summary of our understanding. Journal of Biosciences, 48, 16. (doi: 10.1007/s12038-023-00341-7) (PMID:37204155)

Li, D. et al. (2023) GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3. Journal of Cell Biology, 222(6), e202208151. (doi: 10.1083/jcb.202208151) (PMID:37010470) (PMCID:PMC10072221)

Singh, S. P. , Paschke, P., Tweedy, L. and Insall, R. H. (2022) AKT and SGK kinases regulate cell migration by altering Scar/WAVE complex activation and Arp2/3 complex recruitment. Frontiers in Molecular Biosciences, 9, 965921. (doi: 10.3389/fmolb.2022.965921) (PMID:36106016) (PMCID:PMC9466652)

Singh, S. P. , Thomason, P. A. and Insall, R. H. (2021) Extracellular signalling modulates Scar/WAVE complex activity through Abi phosphorylation. Cells, 10(12), 3485. (doi: 10.3390/cells10123485) (PMID:34943993) (PMCID:PMC8700165)

Yang, Y., Li, D., Chao, X., Singh, S. P. , Thomason, P., Yan, Y., Dong, M., Li, L., Insall, R. H. and Cai, H. (2021) Leep1 interacts with PIP3 and the Scar/WAVE complex to regulate cell migration and macropinocytosis. Journal of Cell Biology, 220(7), e202010096. (doi: 10.1083/jcb.202010096) (PMID:33978708) (PMCID:PMC8127007)

Dhakshinamoorthy, R. and Singh, S. P. (2021) Evolution of reproductive division of labor - lessons learned from the social amoeba Dictyostelium discoideum during its multicellular development. Frontiers in Cell and Developmental Biology, 9, 599525. (doi: 10.3389/fcell.2021.599525) (PMID:33748102) (PMCID:PMC7969725)

Singh, S. P. and Insall, R. H. (2021) Adhesion stimulates Scar/WAVE phosphorylation in mammalian cells. Communicative and Integrative Biology, 14(1), pp. 1-4. (doi: 10.1080/19420889.2020.1855854) (PMID:33447346) (PMCID:PMC7781634)

Singh, S. P. , Thomason, P. A., Lilla, S., Schaks, M., Tang, Q., Goode, B. L., Machesky, L. M. , Rottner, K. and Insall, R. H. (2020) Cell–substrate adhesion drives Scar/WAVE activation and phosphorylation by a Ste20-family kinase, which controls pseudopod lifetime. PLoS Biology, 18(8), e3000774. (doi: 10.1371/journal.pbio.3000774) (PMID:32745097) (PMCID:PMC7425996)

Schaks, M., Singh, S. P. , Kage, F., Thomason, P., Klünemann, T., Steffen, A., Blankenfeldt, W., Stradal, T. E., Insall, R. H. and Rottner, K. (2018) Distinct interaction sites of Rac GTPase with WAVE regulatory complex have non-redundant functions in vivo. Current Biology, 28(22), 3674-3684.e6. (doi: 10.1016/j.cub.2018.10.002) (PMID:30393033) (PMCID:PMC6264382)

Singh, S. P. , Dhakshinamoorthy, R., Jaiswal, P., Schmidt, S., Thewes, S. and Baskar, R. (2014) The thyroxine inactivating gene, type III deiodinase, suppresses multiple signaling centers in Dictyostelium discoideum. Developmental Biology, 396(2), pp. 256-268. (doi: 10.1016/j.ydbio.2014.10.012) (PMID:25446527)

Jaiswal, P., Singh, S. P. , Aiyar, P., Akkali, R. and Baskar, R. (2012) Regulation of multiple tip formation by caffeine in cellular slime molds. BMC Developmental Biology, 12, 26. (doi: 10.1186/1471-213x-12-26) (PMID:22928977) (PMCID:PMC3488011)

Book Sections

Singh, S. P. and Insall, R. H. (2022) Under-agarose chemotaxis and migration assays for dictyostelium. In: Chang, C. and Wang, J. (eds.) Cell Polarity Signaling: Methods and Protocols. Series: Methods in Molecular Biology, 2438. Humana Press: New York, pp. 467-482. ISBN 9781071620342 (doi: 10.1007/978-1-0716-2035-9_27)