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telephone:
01413302988
email:
Marion.McElwee@glasgow.ac.uk
Centre for Virus Research, Sir Michael Stoker building, 464 Bearsden Rd, Glasgow, G61 1hq
Member of the Bhella Group.
Samolej, J., Correa Mendonca, D. , Upfold, N. , McElwee, M., Landsberger, M., Yakimovich, A., Patel, A. H. , Strang, B. L. and Mercer, J. (2024) Bisbenzimide compounds inhibit the replication of prototype and pandemic potential poxviruses. Microbiology Spectrum, 12(4), e04072-23. (doi: 10.1128/spectrum.04072-23) (PMID:38376353) (PMCID:PMC10986486)
Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)
Vijayakrishnan, S. , McElwee, M., Loney, C. , Rixon, F. and Bhella, D. (2020) In situ structure of virus capsids within cell nuclei by correlative light and cryo-electron tomography. Scientific Reports, 10, 17596. (doi: 10.1038/s41598-020-74104-x) (PMID:33077791) (PMCID:PMC7572381)
Saiz-Ros, N. et al. (2019) Host vesicle fusion protein VAPB contributes to the nuclear egress stage of herpes simplex virus type-1 (HSV-1) replication. Cells, 8(2), 120. (doi: 10.3390/cells8020120)
Conley, M. J. , McElwee, M., Azmi, L., Gabrielsen, M. , Byron, O. , Goodfellow, I. G. and Bhella, D. (2019) Calicivirus VP2 forms a portal-like assembly following receptor engagement. Nature, 565(7739), pp. 377-381. (doi: 10.1038/s41586-018-0852-1) (PMID:30626974)
McElwee, M., Vijayakrishnan, S. , Rixon, F. and Bhella, D. (2018) Structure of the herpes-simplex virus portal-vertex. PLoS Biology, 16(6), e2006191. (doi: 10.1371/journal.pbio.2006191) (PMID:29924793) (PMCID:PMC6028144)
Fan, W. H., Robertson, A. P.E., McElwee, M., Bhella, D. , Rixon, F. J. and Lauder, R. (2015) The large tegument protein pUL36 is essential for formation of the capsid vertex-specific component at the capsid-tegument interface of herpes simplex virus 1. Journal of Virology, 89(3), pp. 1502-1511. (doi: 10.1128/JVI.02887-14) (PMID:25410861) (PMCID:PMC4300765)
McElwee, M., Beilstein, F., Labetoulle, M., Rixon, F.J. and Pasdeloup, D. (2013) Dystonin/bpag1 promotes plus-end-directed transport of herpes simplex virus 1 capsids on microtubules during entry. Journal of Virology, 87(20), pp. 11008-11018. (doi: 10.1128/JVI.01633-13)
Pasdeloup, D., McElwee, M., Beilstein, F., Labetoulle, M. and Rixon, F.J. (2013) Herpesvirus tegument protein pUL37 interacts with dystonin/BPAG1 to promote capsid transport on microtubules during egress. Journal of Virology, 87(5), pp. 2857-2867. (doi: 10.1128/JVI.02676-12) (PMID:23269794) (PMCID:PMC3571392)
Pasdeloup, D., Beilstein, F., Roberts, A.P.E., McElwee, M., McNab, D. and Rixon, F.J. (2010) Inner tegument protein pUL37 of herpes simplex virus type 1 is involved in directing capsids to the trans-Golgi network for envelopment. Journal of General Virology, 91(9), pp. 2145-2151. (doi: 10.1099/vir.0.022053-0) (PMID:20505007) (PMCID:PMC3066548)
Hope, R.G., McElwee, M.J. and McLauchlan, J. (2006) Efficient cleavage by signal peptide peptidase requires residues within the signal peptide between the core and E1 proteins of hepatitis C virus strain J1. Journal of General Virology, 87(3), pp. 623-627. (doi: 10.1099/vir.0.81371-0) (PMID:16476983)
Targett-Adams, P., McElwee, M.J., Ehrenborg, E., Gustafsson, M.C., Palmer, C.N. and McLauchlan, J. (2005) A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein. BBA: Gene Structure and Expression, 1728(1-2), pp. 95-104. (doi: 10.1016/j.bbaexp.2005.01.017)
Samolej, J., Correa Mendonca, D. , Upfold, N. , McElwee, M., Landsberger, M., Yakimovich, A., Patel, A. H. , Strang, B. L. and Mercer, J. (2024) Bisbenzimide compounds inhibit the replication of prototype and pandemic potential poxviruses. Microbiology Spectrum, 12(4), e04072-23. (doi: 10.1128/spectrum.04072-23) (PMID:38376353) (PMCID:PMC10986486)
Rihn, S. J. et al. (2021) A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biology, 19(2), e3001091. (doi: 10.1371/journal.pbio.3001091) (PMID:33630831) (PMCID:PMC7906417)
Vijayakrishnan, S. , McElwee, M., Loney, C. , Rixon, F. and Bhella, D. (2020) In situ structure of virus capsids within cell nuclei by correlative light and cryo-electron tomography. Scientific Reports, 10, 17596. (doi: 10.1038/s41598-020-74104-x) (PMID:33077791) (PMCID:PMC7572381)
Saiz-Ros, N. et al. (2019) Host vesicle fusion protein VAPB contributes to the nuclear egress stage of herpes simplex virus type-1 (HSV-1) replication. Cells, 8(2), 120. (doi: 10.3390/cells8020120)
Conley, M. J. , McElwee, M., Azmi, L., Gabrielsen, M. , Byron, O. , Goodfellow, I. G. and Bhella, D. (2019) Calicivirus VP2 forms a portal-like assembly following receptor engagement. Nature, 565(7739), pp. 377-381. (doi: 10.1038/s41586-018-0852-1) (PMID:30626974)
McElwee, M., Vijayakrishnan, S. , Rixon, F. and Bhella, D. (2018) Structure of the herpes-simplex virus portal-vertex. PLoS Biology, 16(6), e2006191. (doi: 10.1371/journal.pbio.2006191) (PMID:29924793) (PMCID:PMC6028144)
Fan, W. H., Robertson, A. P.E., McElwee, M., Bhella, D. , Rixon, F. J. and Lauder, R. (2015) The large tegument protein pUL36 is essential for formation of the capsid vertex-specific component at the capsid-tegument interface of herpes simplex virus 1. Journal of Virology, 89(3), pp. 1502-1511. (doi: 10.1128/JVI.02887-14) (PMID:25410861) (PMCID:PMC4300765)
McElwee, M., Beilstein, F., Labetoulle, M., Rixon, F.J. and Pasdeloup, D. (2013) Dystonin/bpag1 promotes plus-end-directed transport of herpes simplex virus 1 capsids on microtubules during entry. Journal of Virology, 87(20), pp. 11008-11018. (doi: 10.1128/JVI.01633-13)
Pasdeloup, D., McElwee, M., Beilstein, F., Labetoulle, M. and Rixon, F.J. (2013) Herpesvirus tegument protein pUL37 interacts with dystonin/BPAG1 to promote capsid transport on microtubules during egress. Journal of Virology, 87(5), pp. 2857-2867. (doi: 10.1128/JVI.02676-12) (PMID:23269794) (PMCID:PMC3571392)
Pasdeloup, D., Beilstein, F., Roberts, A.P.E., McElwee, M., McNab, D. and Rixon, F.J. (2010) Inner tegument protein pUL37 of herpes simplex virus type 1 is involved in directing capsids to the trans-Golgi network for envelopment. Journal of General Virology, 91(9), pp. 2145-2151. (doi: 10.1099/vir.0.022053-0) (PMID:20505007) (PMCID:PMC3066548)
Hope, R.G., McElwee, M.J. and McLauchlan, J. (2006) Efficient cleavage by signal peptide peptidase requires residues within the signal peptide between the core and E1 proteins of hepatitis C virus strain J1. Journal of General Virology, 87(3), pp. 623-627. (doi: 10.1099/vir.0.81371-0) (PMID:16476983)
Targett-Adams, P., McElwee, M.J., Ehrenborg, E., Gustafsson, M.C., Palmer, C.N. and McLauchlan, J. (2005) A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein. BBA: Gene Structure and Expression, 1728(1-2), pp. 95-104. (doi: 10.1016/j.bbaexp.2005.01.017)
Furnon, W. , Cowton, V. M., De Lorenzo, G. , Orton, R. , Herder, V. , Cantoni, D. , Ilia, G., Correa Mendonca, D. , Kerr, K., Allan, J., Upfold, N. , Meehan, G. R. , Bakshi, S., Das, U. R., Molina Arias, S., McElwee, M., Little, S., Logan, N., Kwok, K. , Smollett, K. , Willett, B. , Da Silva Filipe, A. , Robertson, D. L. , Grove, J. , Patel, A. H. and Palmarini, M. (2024) Phenotypic evolution of SARS-CoV-2 spike throughout the COVID-19 pandemic. [Data Collection]
