Dr Katie Hughes
- Research Associate (Parasitology)
telephone:
01413305616
email:
Katie.Hughes@glasgow.ac.uk
RB513 Level B5, Iii - Gbrc, University Place, Glasgow G12 8TA
Publications
2024
Hughes, K. R. and Waters, A. P. (2024) Plasmodium falciparum artemisinin resistance: something gained in translation. Trends in Parasitology, 40(7), pp. 541-543. (doi: 10.1016/j.pt.2024.06.004) (PMID:38910099)
2021
Simwela, N., Hughes, K. R., Rennie, M. T., Barrett, M. P. and Waters, A. P. (2021) Mammalian deubiquitinating enzyme inhibitors display. ACS Infectious Diseases, 7(2), pp. 333-346. (doi: 10.1021/acsinfecdis.0c00580) (PMID:33400499)
2020
Simwela, N., Hughes, K. R., Roberts, A. B., Rennie, M. T., Barrett, M. P. and Waters, A. P. (2020) Experimentally engineered mutations in a ubiquitin hydrolase, UBP-1, modulate in vivo susceptibility to artemisinin and chloroquine in Plasmodium berghei. Antimicrobial Agents and Chemotherapy, 64(7), (doi: 10.1128/AAC.02484-19) (PMID:32340987) (PMCID:PMC7318008)
Patil, H., Hughes, K. R., Lemgruber Soares, L. , Philip, N., Dickens, N. , Starnes, G. L. and Waters, A. P. (2020) Zygote morphogenesis but not the establishment of cell polarity in Plasmodium berghei is controlled by the small GTPase, RAB11A. PLoS Pathogens, 16(5), e1008091. (doi: 10.1371/journal.ppat.1008091) (PMID:32463831) (PMCID:PMC7255598)
2018
De Niz, M. et al. (2018) Plasmodium gametocytes display homing and vascular transmigration in the host bone marrow. Science Advances, 4(5), eaat3775. (doi: 10.1126/sciadv.aat3775) (PMID:29806032) (PMCID:PMC5966192)
2017
Hughes, K. R. and Waters, A. P. (2017) Rapid inducible protein displacement in Plasmodium in vivo and in vitro using knocksideways technology. Wellcome Open Research, 2, 18. (doi: 10.12688/wellcomeopenres.11005.1) (PMID:28428983) (PMCID:PMC5395084)
2016
Srivastava, A., Philip, N., Hughes, K. R., Georgiou, K., MacRae, J. I., Barrett, M. P. , Creek, D. J., McConville, M. J. and Waters, A. P. (2016) Stage-specific changes in plasmodium metabolism required for differentiation and adaptation to different host and vector environments. PLoS Pathogens, 12(12), e1006094. (doi: 10.1371/journal.ppat.1006094) (PMID:28027318) (PMCID:PMC5189940)
2014
Sinha, A. et al. (2014) A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium. Nature, 507(7491), pp. 253-257. (doi: 10.1038/nature12970) (PMID:24572359) (PMCID:PMC4105895)
2010
Hughes, K.R., Philip, N., Lucas Starnes, G., Taylor, S. and Waters, A.P. (2010) From cradle to grave: RNA biology in malaria parasites. Wiley Interdisciplinary Reviews: RNA, 1(2), pp. 287-303. (doi: 10.1002/wrna.30)
Hughes, K. R., Biagini, G. A. and Craig, A. G. (2010) Continued cytoadherence of Plasmodium falciparum infected red blood cells after antimalarial treatment. Molecular and Biochemical Parasitology, 169(2), pp. 71-78. (doi: 10.1016/j.molbiopara.2009.09.007)
2008
Maier, A. G. et al. (2008) Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes. Cell, 134(1), pp. 48-61. (doi: 10.1016/j.cell.2008.04.051)
Chakravorty, S. J., Hughes, K. R. and Craig, A. G. (2008) Host response to cytoadherence in plasmodium falciparum. Biochemical Society Transactions, 36(Pt 2), pp. 221-228. (doi: 10.1042/BST0360221) (PMID:18363564)
2007
Hughes, K., Wand, M., Foulston, L., Young, R., Harley, K., Terry, S., Ersfeld, K. and Rudenko, G. (2007) A novel ISWI is involved in VSG expression site downregulation in African trypanosomes. EMBO Journal, 26(9), pp. 2400-2410. (doi: 10.1038/sj.emboj.7601678)
Articles
Hughes, K. R. and Waters, A. P. (2024) Plasmodium falciparum artemisinin resistance: something gained in translation. Trends in Parasitology, 40(7), pp. 541-543. (doi: 10.1016/j.pt.2024.06.004) (PMID:38910099)
Simwela, N., Hughes, K. R., Rennie, M. T., Barrett, M. P. and Waters, A. P. (2021) Mammalian deubiquitinating enzyme inhibitors display. ACS Infectious Diseases, 7(2), pp. 333-346. (doi: 10.1021/acsinfecdis.0c00580) (PMID:33400499)
Simwela, N., Hughes, K. R., Roberts, A. B., Rennie, M. T., Barrett, M. P. and Waters, A. P. (2020) Experimentally engineered mutations in a ubiquitin hydrolase, UBP-1, modulate in vivo susceptibility to artemisinin and chloroquine in Plasmodium berghei. Antimicrobial Agents and Chemotherapy, 64(7), (doi: 10.1128/AAC.02484-19) (PMID:32340987) (PMCID:PMC7318008)
Patil, H., Hughes, K. R., Lemgruber Soares, L. , Philip, N., Dickens, N. , Starnes, G. L. and Waters, A. P. (2020) Zygote morphogenesis but not the establishment of cell polarity in Plasmodium berghei is controlled by the small GTPase, RAB11A. PLoS Pathogens, 16(5), e1008091. (doi: 10.1371/journal.ppat.1008091) (PMID:32463831) (PMCID:PMC7255598)
De Niz, M. et al. (2018) Plasmodium gametocytes display homing and vascular transmigration in the host bone marrow. Science Advances, 4(5), eaat3775. (doi: 10.1126/sciadv.aat3775) (PMID:29806032) (PMCID:PMC5966192)
Hughes, K. R. and Waters, A. P. (2017) Rapid inducible protein displacement in Plasmodium in vivo and in vitro using knocksideways technology. Wellcome Open Research, 2, 18. (doi: 10.12688/wellcomeopenres.11005.1) (PMID:28428983) (PMCID:PMC5395084)
Srivastava, A., Philip, N., Hughes, K. R., Georgiou, K., MacRae, J. I., Barrett, M. P. , Creek, D. J., McConville, M. J. and Waters, A. P. (2016) Stage-specific changes in plasmodium metabolism required for differentiation and adaptation to different host and vector environments. PLoS Pathogens, 12(12), e1006094. (doi: 10.1371/journal.ppat.1006094) (PMID:28027318) (PMCID:PMC5189940)
Sinha, A. et al. (2014) A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium. Nature, 507(7491), pp. 253-257. (doi: 10.1038/nature12970) (PMID:24572359) (PMCID:PMC4105895)
Hughes, K.R., Philip, N., Lucas Starnes, G., Taylor, S. and Waters, A.P. (2010) From cradle to grave: RNA biology in malaria parasites. Wiley Interdisciplinary Reviews: RNA, 1(2), pp. 287-303. (doi: 10.1002/wrna.30)
Hughes, K. R., Biagini, G. A. and Craig, A. G. (2010) Continued cytoadherence of Plasmodium falciparum infected red blood cells after antimalarial treatment. Molecular and Biochemical Parasitology, 169(2), pp. 71-78. (doi: 10.1016/j.molbiopara.2009.09.007)
Maier, A. G. et al. (2008) Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes. Cell, 134(1), pp. 48-61. (doi: 10.1016/j.cell.2008.04.051)
Chakravorty, S. J., Hughes, K. R. and Craig, A. G. (2008) Host response to cytoadherence in plasmodium falciparum. Biochemical Society Transactions, 36(Pt 2), pp. 221-228. (doi: 10.1042/BST0360221) (PMID:18363564)
Hughes, K., Wand, M., Foulston, L., Young, R., Harley, K., Terry, S., Ersfeld, K. and Rudenko, G. (2007) A novel ISWI is involved in VSG expression site downregulation in African trypanosomes. EMBO Journal, 26(9), pp. 2400-2410. (doi: 10.1038/sj.emboj.7601678)