2024

Cuahtecontzi Delint, R. et al. (2024) Nanotopography influences host-pathogen quorum sensing and facilitates selection of bioactive metabolites in mesenchymal stromal cells and pseudomonas aeruginosa co-cultures. ACS Applied Materials and Interfaces, (doi: 10.1021/acsami.4c09291) (PMID:39113638) (Early Online Publication)

2023

Delaney, C., Short, B., Rajendran, R., Kean, R., Burgess, K., Williams, C., Munro, C. A. and Ramage, G. (2023) An integrated transcriptomic and metabolomic approach to investigate the heterogeneous Candida albicans biofilm phenotype. Biofilm, 5, 100112. (doi: 10.1016/j.bioflm.2023.100112) (PMID:36969800) (PMCID:PMC10034394)

Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)

2022

Cortada‐Garcia, J., Haggarty, J., Moses, T., Daly, R. , Arnold, S. A. and Burgess, K. (2022) On‐line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process. Biotechnology and Bioengineering, 119(10), pp. 2757-2769. (doi: 10.1002/bit.28173) (PMID:35798686) (PMCID:PMC9541951)

Díaz, M. L., Burgess, K., Burchmore, R. , Gómez, M. A., Gómez-Ochoa, S. A., Echeverría, L. E., Morillo, C. and González, C. I. (2022) Metabolomic profiling of end-stage heart failure secondary to chronic Chagas cardiomyopathy. International Journal of Molecular Sciences, 23(18), 10456. (doi: 10.3390/ijms231810456) (PMID:36142367) (PMCID:PMC9499603)

Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)

2021

Nile, D. L., Rae, C. , Walker, D. J. , Canning Waddington, J., Vincent, I. , Burgess, K., Gaze, M. N., Mairs, R. J. and Chalmers, A. J. (2021) Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells. Cancer and Metabolism, 9, 24. (doi: 10.1186/s40170-021-00258-5) (PMID:34011385) (PMCID:PMC8136224)

McLuskey, K., Wandy, J. , Vincent, I. , Van Der Hooft, J. J.J. , Rogers, S. , Burgess, K. and Daly, R. (2021) Ranking metabolite sets by their activity levels. Metabolites, 11(2), 103. (doi: 10.3390/metabo11020103) (PMID:33670102) (PMCID:PMC7916825)

Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)

2020

Pesko, B. K., Weidt, S., McLaughlin, M. , Wescott, D. J., Torrance, H., Burgess, K. and Burchmore, R. (2020) Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death. OMICS: A Journal of Integrative Biology, 24(11), pp. 649-659. (doi: 10.1089/omi.2020.0084) (PMID:33095683)

Blackburn, G. et al. (2020) Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest. Metabolites, 10(10), 399. (doi: 10.3390/metabo10100399) (PMID:33050077) (PMCID:PMC7600507)

Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)

Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)

Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)

Burgon, J. D. , Vieites, D. R., Jacobs, A. , Weidt, S. K., Gunter, H. M., Steinfartz, S., Burgess, K., Marble, B. K. and Elmer, K. R. (2020) Functional colour genes and signals of selection in colour polymorphic salamanders. Molecular Ecology, 29(7), pp. 1284-1299. (doi: 10.1111/mec.15411) (PMID:32159878)

2019

Buckley, J., Daly, R. , Cobbold, C. A. , Burgess, K. and Mable, B. K. (2019) Changing environments and genetic variation: natural variation in inbreeding does not compromise short-term physiological responses. Proceedings of the Royal Society of London Series B: Biological Sciences, 286(1915), 20192109. (doi: 10.1098/rspb.2019.2109) (PMID:31744436) (PMCID:PMC6892046)

Vargas, D. A., Prieto, M. D., Martínez-Valencia, A. J., Cossio, A., Burgess, K. E.V., Burchmore, R. J.S. and Gómez, M. A. (2019) Pharmacometabolomics of meglumine antimoniate in patients with cutaneous leishmaniasis. Frontiers in Pharmacology, 10, 657. (doi: 10.3389/fphar.2019.00657) (PMID:31281253) (PMCID:PMC6595045)

Rankin, N. J. , Burgess, K., Weidt, S., Wannamethee, G., Sattar, N. and Welsh, P. (2019) High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry. Annals of Clinical Biochemistry, 56(3), pp. 397-407. (doi: 10.1177/0004563219830432) (PMID:30832481) (PMCID:PMC6498755)

2018

van der Hooft, J. J.J., Alghefari, W., Watson, E., Everest, P. , Morton, F. R. , Burgess, K. E.V. and Smith, D. G.E. (2018) Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose. Metabolomics, 14(11), 144. (doi: 10.1007/s11306-018-1438-5) (PMID:30830405) (PMCID:PMC6208705)

Megalios, A., Daly, R. and Burgess, K. (2018) MetaboCraft: building a Minecraft plugin for metabolomics. Bioinformatics, 34(15), pp. 2693-2694. (doi: 10.1093/bioinformatics/bty102) (PMID:29608638) (PMCID:PMC6061834)

Newton, J., Ramage, G. , Gadegaard, N. , Zachs, W., Rogers, S. , Barrett, M. P. , Carruthers, G. and Burgess, K. (2018) Minimally-destructive atmospheric ionisation mass spectrometry authenticates authorship of historical manuscripts. Scientific Reports, 8, 10944. (doi: 10.1038/s41598-018-28810-2) (PMID:30050048) (PMCID:PMC6062563)

2017

Burgess, K.E.V., Borutzki, Y., Rankin, N. , Daly, R. and Jourdan, S. (2017) MetaNetter 2: a Cytoscape plugin for ab initio network analysis and metabolite feature classification. Journal of Chromatography B, 1071, pp. 68-74. (doi: 10.1016/j.jchromb.2017.08.015) (PMID:29030098) (PMCID:PMC5726607)

Gloaguen, Y. , Morton, F. , Daly, R. , Gurden, R., Rogers, S. , Wandy, J. , Wilson, D., Barrett, M. and Burgess, K. (2017) PiMP my metabolome: An integrated, web-based tool for LC-MS metabolomics data. Bioinformatics, 33(24), pp. 4007-4009. (doi: 10.1093/bioinformatics/btx499) (PMID:28961954) (PMCID:PMC5860087)

Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)

Zambelloni, R., Connolly, J. P.R., Huerta Uribe, A. , Burgess, K., Marquez, R. and Roe, A. J. (2017) Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition. Molecular Microbiology, 105(4), pp. 606-619. (doi: 10.1111/mmi.13719) (PMID:28557017) (PMCID:PMC5575525)

Alakpa, E. V., Jayawarna, V., Burgess, K. E.V., West, C. C., Péault, B., Ulijn, R. V. and Dalby, M. J. (2017) Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels. Scientific Reports, 7, 6895. (doi: 10.1038/s41598-017-07255-z) (PMID:28761049) (PMCID:PMC5537289)

Alakpa, E. V., Burgess, K. E.V., Chung, P., Riehle, M. O. , Gadegaard, N. , Dalby, M. J. and Cusack, M. (2017) Nacre topography produces higher crystallinity in bone than chemically induced osteogenesis. ACS Nano, 11(7), pp. 6717-6727. (doi: 10.1021/acsnano.7b01044) (PMID:28665112)

van der Hooft, J. J.J. , Wandy, J. , Young, F., Padmanabhan, S. , Gerasimidis, K. , Burgess, K. E.V., Barrett, M. P. and Rogers, S. (2017) Unsupervised discovery and comparison of structural families across multiple samples in untargeted metabolomics. Analytical Chemistry, 89(14), pp. 7569-7577. (doi: 10.1021/acs.analchem.7b01391) (PMID:28621528) (PMCID:PMC5524435)

Mwenechanya, R. et al. (2017) Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. PLoS Neglected Tropical Diseases, 11(6), e0005649. (doi: 10.1371/journal.pntd.0005649) (PMID:28622334) (PMCID:PMC5498063)

Kean, R. et al. (2017) Candida albicans mycofilms support Staphylococcus aureus colonization and enhances miconazole resistance in dual-species interactions. Frontiers in Microbiology, 8, 258. (doi: 10.3389/fmicb.2017.00258)

Akpunarlieva, S., Weidt, S., Lamasudin, D., Naula, C. , Henderson, D., Barrett, M. , Burgess, K. and Burchmore, R. (2017) Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania. Journal of Proteomics, 155, pp. 85-98. (doi: 10.1016/j.jprot.2016.12.009) (PMID:28040509)

Haggarty, J. and Burgess, K. E.V. (2017) Recent advances in liquid and gas chromatography methodology for extending coverage of the metabolome. Current Opinion in Biotechnology, 43, pp. 77-85. (doi: 10.1016/j.copbio.2016.09.006) (PMID:27771607)

Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)

2016

Weidt, S., Haggarty, J., Kean, R., Cojocariu, C. I., Silcock, P. J., Rajendran, R., Ramage, G. and Burgess, K. E. V. (2016) A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms. Metabolomics, 12, 189. (doi: 10.1007/s11306-016-1134-2) (PMID:28003796) (PMCID:PMC5097782)

van Der Hooft, J. J. J. , Wandy, J. , Barrett, M. P. , Burgess, K. E.V. and Rogers, S. (2016) Topic modeling for untargeted substructure exploration in metabolomics. Proceedings of the National Academy of Sciences of the United States of America, 113(48), pp. 13738-13743. (doi: 10.1073/pnas.1608041113) (PMID:27856765) (PMCID:PMC5137707)

Rajendran, R. et al. (2016) Integrating Candida albicans metabolism with biofilm heterogeneity by transcriptome mapping. Scientific Reports, 6, 35436. (doi: 10.1038/srep35436) (PMID:27765942) (PMCID:PMC5073228)

Thomas, F., Mudaliar, M. , Tassi, R., Mcneilly, T., Burchmore, R. , Burgess, K., Herzyk, P. , Zadoks, R. and Eckersall, P. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics. Molecular BioSystems, 12(9), pp. 2762-2769. (doi: 10.1039/C6MB00289G) (PMID:27412568)

Alakpa, E. et al. (2016) Tunable supramolecular hydrogels for selection of lineage guiding metabolites in stem cell cultures. Chem, 1(2), pp. 298-319. (doi: 10.1016/j.chempr.2016.07.001)

Van Der Hooft, J. , Padmanabhan, S. , Burgess, K. and Barrett, M. (2016) Erratum to: Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12(8), 139. (doi: 10.1007/s11306-016-1078-6)

Roberts, J. N. et al. (2016) Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation. ACS Nano, 10(7), pp. 6667-6679. (doi: 10.1021/acsnano.6b01765) (PMID:27322014) (PMCID:PMC4963921)

Van Der Hooft, J. J.J. , Padmanabhan, S. , Burgess, K. E.V. and Barrett, M. P. (2016) Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12, 125. (doi: 10.1007/s11306-016-1064-z) (PMID:27471437) (PMCID:PMC4932139)

Stipetic, L. H., Dalby, M. J. , Davies, R. L. , Morton, F. r. , Ramage, G. and Burgess, K. (2016) A novel metabolomic approach used for the comparison of Staphylococcus aureus planktonic cells and biofilm samples. Metabolomics, 12, 75. (doi: 10.1007/s11306-016-1002-0) (PMID:27013931) (PMCID:PMC4783440)

2015

Kim, D.-H., Achcar, F. , Breitling, R. , Burgess, K. E. and Barrett, M. P. (2015) LC–MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes. Metabolomics, 11(6), pp. 1721-1732. (doi: 10.1007/s11306-015-0827-2) (PMID:26491423) (PMCID:PMC4605981)

Haggarty, J., Oppermann, M., Dalby, M. J. , Burchmore, R. J. , Cook, K., Weidt, S. and Burgess, K. E.V. (2015) Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome. Metabolomics, 11(5), pp. 1465-1470. (doi: 10.1007/s11306-014-0770-7) (PMID:26366140) (PMCID:PMC4559102)

Stipetic, L. H., Hamilton, G., Dalby, M. J. , Davies, R. L. , Meek, R.M. D., Ramage, G. , Smith, D. G.E. and Burgess, K. E.V. (2015) Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip. Genome Announcements, 3(2), e00336-15. (doi: 10.1128/genomeA.00336-15) (PMID:25931597) (PMCID:PMC4417693)

Connolly, J. P.R., Goldstone, R. J., Burgess, K., Cogdell, R. J. , Beatson, S. A., Vollmer, W., Smith, D. G.E. and Roe, A. (2015) The host metabolite D-serine contributes to bacterial niche specificity through gene selection. ISME Journal, 9, pp. 1039-1051. (doi: 10.1038/ismej.2014.242) (PMID:25526369) (PMCID:PMC4366372)

Creek, D. J. et al. (2015) Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLoS Pathogens, 11(3), e1004689. (doi: 10.1371/journal.ppat.1004689) (PMID:25775470) (PMCID:PMC4361558)

van der Hooft, J. , Ridder, L., Barrett, M. P. and Burgess, K. V. (2015) Enhanced acylcarnitine annotation in high-resolution mass spectrometry data: fragmentation analysis for the classification and annotation of acylcarnitines. Frontiers in Bioengineering and Biotechnology, 3, p. 26. (doi: 10.3389/fbioe.2015.00026) (PMID:25806366) (PMCID:PMC4353373)

Alkhaldi, A.A.M., Creek, D.J., Ibrahim, H., Kim, D.-H., Quashie, N.B., Burgess, K.E., Changtam, C., Barrett, M.P. , Suksamrarn, A. and De Koning, H.P. (2015) Potent Trypanocidal curcumin analogs bearing a monoenone linker motif act on Trypanosoma brucei by forming an adduct with Trypanothione. Molecular Pharmacology, 87(3), pp. 451-464. (doi: 10.1124/mol.114.096016) (PMID:25527638)

McNamara, L. E., Turner, L.-A. and Burgess, K. V. (2015) Systems biology approaches applied to regenerative medicine. Current Pathobiology Reports, 3(1), pp. 37-45. (doi: 10.1007/s40139-015-0072-4) (PMID:25722955) (PMCID:PMC4333234)

Alakpa, E., Burgess, K., Chung, P., Dalby, M. and Cusack, M. (2015) Topographical Bridging Between Bone and Nacre. International Society for Stem Cell Research (ISSCR), Stockholm, Sweden, 24-27th Jun 2015.

2014

Rankin, N. J. , Preiss, D. , Welsh, P. , Burgess, K. E.V., Nelson, S. M. , Lawlor, D. A. and Sattar, N. (2014) The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective. Atherosclerosis, 237(1), pp. 287-300. (doi: 10.1016/j.atherosclerosis.2014.09.024) (PMID:25299963) (PMCID:PMC4232363)

Yang, J., McNamara, L. E., Gadegaard, N. , Alakpa, E. V., Burgess, K. V., Meek, D. and Dalby, M. J. (2014) Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs. ACS Nano, 8(10), pp. 9941-9953. (doi: 10.1021/nn504767g) (PMID:25227207)

Daly, R. , Rogers, S. , Wandy, J., Jankevics, A., Burgess, K. E.V. and Breitling, R. (2014) MetAssign: probabilistic annotation of metabolites from LC–MS data using a Bayesian clustering approach. Bioinformatics, 30(19), pp. 2764-2771. (doi: 10.1093/bioinformatics/btu370) (PMID:24916385) (PMCID:PMC4173012)

Evans, S., Burgess, K. E.V. and Gray, J. V. (2014) Recovery from Rapamycin: drug-insensitive activity of yeast target of rapamycin complex 1 (torc1) supports residual proliferation that dilutes rapamycin among progeny cells. Journal of Biological Chemistry, 289(38), pp. 26554-26565. (doi: 10.1074/jbc.M114.589754) (PMID:25104356) (PMCID:PMC4176226)

Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93(1), pp. 199-211. (doi: 10.1111/mmi.12651) (PMID:24846743) (PMCID:PMC4249723)

Vincent, I. M. , Weidt, S., Rivas, L., Burgess, K., Smith, T. K. and Ouellette, M. (2014) Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism. International Journal for Parasitology: Drugs and Drug Resistance, 4(1), pp. 20-27. (doi: 10.1016/j.ijpddr.2013.11.002) (PMID:24596665) (PMCID:PMC3940234)

Tsimbouri, P. , Gadegaard, N., Burgess, K., White, K., Reynolds, P. , Herzyk, P. , Oreffo, R. and Dalby, M.J. (2014) Nanotopographical effects on mesenchymal stem cell morphology and phenotype. Journal of Cellular Biochemistry, 115(2), pp. 380-390. (doi: 10.1002/jcb.24673) (PMID:24123223)

Alakpa, E., Burgess, K., Dalby, M. and Cusack, M. (2014) Investigating the 'Bone-Shell Divide': Pearl Oyster Shell Topography as a Means of Directing Stem Cell Behaviour. European Society for Biomaterials (ESB 2014), Liverpool, UK, 31st Aug–3rd Sep 2014. (Unpublished)

Burgess, K., Rankin, N. and Weidt, S. (2014) Metabolomics. In: Padmanabhan, S. (ed.) Handbook of Pharmacogenomics and Stratified Medicine. Academic Press: London, pp. 181-205. ISBN 9780123868824 (doi: 10.1016/B978-0-12-386882-4.00010-4)

2013

Lipina, C., Macrae, K., Suhm, T., Weigert, C., Blachnio-Zabielska, A., Baranowski, M., Gorski, J., Burgess, K. and Hundal, H. S. (2013) Mitochondrial substrate availability and its role in lipid-induced insulin resistance and proinflammatory signaling in skeletal muscle. Diabetes, 62(10), pp. 3426-3436. (doi: 10.2337/db13-0264) (PMID:23733201) (PMCID:PMC3781443)

Rupp, A.F., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J., Cappell, J., Burgess, K., Matiasek, K., McGonigal, R. and Willison, H.J. (2013) Anti-GM2 ganglioside antibodies are a biomarker for acute canine polyradiculoneuritis. Journal of the Peripheral Nervous System, 18(1), pp. 75-88. (doi: 10.1111/jns5.12011) (PMID:23521648)

Ali, J.A.M., Creek, D.J., Burgess, K., Allison, H.C., Field, M.C., Maser, P. and De Koning, H.P. (2013) Pyrimidine salvage in trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines. Molecular Pharmacology, 83(2), pp. 439-453. (doi: 10.1124/mol.112.082321) (PMID:23188714)

Alakpa, E., Jayawarna, V., Burgess, K., Ulijn, R. and Dalby, M. (2013) Combining Hydrogels With Tuned Stiffness and Metabolomics to Identify Small Molecules that Drive Mesenchymal Stem Cell Differentiation. European Materials Research Society (E-MRS), Strasbourg, France, 27-31 May 2013.

Seras-Franzoso, J., Tsimbouri, P.M. , Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J. (2013) Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces. Nanomedicine, 9(2), pp. 207-220. (doi: 10.2217/nnm.13.43) (PMID:23631503)

2012

Tsimbouri, P.M. , McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, P. , Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N. and Dalby, M.J. (2012) Using nanotopography and metabolomics to identify biochemical effectors of multipotency. ACS Nano, 6(11), pp. 10239-10249. (doi: 10.1021/nn304046m)

Creek, D.J., Chokkathukalam, A., Jankevics, A., Burgess, K.E.V., Breitling, R. and Barrett, M.P. (2012) Stable isotope-assisted metabolomics for network-wide metabolic pathway elucidation. Analytical Chemistry, 84(20), pp. 8442-8447. (doi: 10.1021/ac3018795) (PMID:22946681) (PMCID:PMC3472505)

Burgess, K.E.V. and Burchmore, R.J.S. (2012) Strategies to dissect parasite proteomes. Parasitology, 139(9), pp. 1119-1130. (doi: 10.1017/S0031182011002368)

Lockman, K.A. et al. (2012) Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis. Liver International, 32(7), pp. 1079-1092. (doi: 10.1111/j.1478-3231.2012.02775.x)

Creek, D.J., Jankevics, A., Burgess, K.E.V., Breitling, R. and Barrett, M.P. (2012) IDEOM: an excel interface for analysis of LC-MS based metabolomics data. Bioinformatics, 28(7), pp. 1048-1049. (doi: 10.1093/bioinformatics/bts069) (PMID:22308147)

Alakpa, E.V., Burgess, K., Jayawarna, V., Ulijn, R. and Dalby, M. (2012) Development of Biomaterials for Cellular Differentiation Using a Metabolomics Approach. 3rd TERMIS World Congress, Vienna, Austria, 5-8 Sep 2012. p. 238.

Alakpa, E., Jayarwarna, V., Burgess, K. and Dalby, M. (2012) Characterisation of peptide biomaterials & innate metabolites that direct stem cell differentiation in vitro. European Cell and Materials, 23(Sup 4), p. 50.

Vincent, I.M. , Creek, D.J., Burgess, K., Woods, D.J., Burchmore, R.J.S. and Barrett, M.P. (2012) Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against trypanosoma brucei. PLoS Neglected Tropical Diseases, 6(5), e1618. (doi: 10.1371/journal.pntd.0001618) (PMID:22563508) (PMCID:PMC3341325)

2011

Burgess, K., Creek, D., Dewsbury, P., Cook, K. and Barrett, M.P. (2011) Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry. Rapid Communications in Mass Spectrometry, 25(22), pp. 3447-3452. (doi: 10.1002/rcm.5247)

Leader, D.P. , Burgess, K., Creek, D. and Barrett, M.P. (2011) Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry. Rapid Communications in Mass Spectrometry, 25(22), pp. 3422-3426. (doi: 10.1002/rcm.5245)

McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)

McMurray, R.J., Gadegaard, N. , Tsimbouri, P.M. , Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nature Materials, 10(8), pp. 637-644. (doi: 10.1038/nmat3058) (PMID:21765399)

Alakpa, E., Jayawarna, V., Burgess, K. and Dalby, M. (2011) Elucidating cellular reaction to biomaterial substrates using a metabolomics approach. European Cells and Materials, 22(Sup 3), p. 18.

Creek, D.J., Jankevics, A., Breitling, R. , Watson, D.G., Barrett, M.P. and Burgess, K.E.V. (2011) Toward global metabolomics snalysis with Hydrophilic Interaction Liquid Chromatography–Mass Spectrometry: improved metabolite identification by retention time prediction. Analytical Chemistry, 83(22), pp. 8703-8710. (doi: 10.1021/ac2021823)

Tsimbouri, P. , Gadegaard, N. , Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography. Histology and Histopathology: Cellular and Molecular Biology, 26(S1), 31.012.

2010

Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Riehle, M.O. , Oreffo, R.O., Dalby, M.J. and Burchmore, R. (2010) Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells. Acta Biomaterialia, 6(9), pp. 3694-3703. (doi: 10.1016/j.actbio.2010.02.038)

2009

Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Burchmore, R.J. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling. Biomaterials, 30(27), pp. 4723-4731. (doi: 10.1016/j.biomaterials.2009.05.040)

Articles

Cuahtecontzi Delint, R. et al. (2024) Nanotopography influences host-pathogen quorum sensing and facilitates selection of bioactive metabolites in mesenchymal stromal cells and pseudomonas aeruginosa co-cultures. ACS Applied Materials and Interfaces, (doi: 10.1021/acsami.4c09291) (PMID:39113638) (Early Online Publication)

Delaney, C., Short, B., Rajendran, R., Kean, R., Burgess, K., Williams, C., Munro, C. A. and Ramage, G. (2023) An integrated transcriptomic and metabolomic approach to investigate the heterogeneous Candida albicans biofilm phenotype. Biofilm, 5, 100112. (doi: 10.1016/j.bioflm.2023.100112) (PMID:36969800) (PMCID:PMC10034394)

Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)

Cortada‐Garcia, J., Haggarty, J., Moses, T., Daly, R. , Arnold, S. A. and Burgess, K. (2022) On‐line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process. Biotechnology and Bioengineering, 119(10), pp. 2757-2769. (doi: 10.1002/bit.28173) (PMID:35798686) (PMCID:PMC9541951)

Díaz, M. L., Burgess, K., Burchmore, R. , Gómez, M. A., Gómez-Ochoa, S. A., Echeverría, L. E., Morillo, C. and González, C. I. (2022) Metabolomic profiling of end-stage heart failure secondary to chronic Chagas cardiomyopathy. International Journal of Molecular Sciences, 23(18), 10456. (doi: 10.3390/ijms231810456) (PMID:36142367) (PMCID:PMC9499603)

Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)

Nile, D. L., Rae, C. , Walker, D. J. , Canning Waddington, J., Vincent, I. , Burgess, K., Gaze, M. N., Mairs, R. J. and Chalmers, A. J. (2021) Inhibition of glycolysis and mitochondrial respiration promotes radiosensitisation of neuroblastoma and glioma cells. Cancer and Metabolism, 9, 24. (doi: 10.1186/s40170-021-00258-5) (PMID:34011385) (PMCID:PMC8136224)

McLuskey, K., Wandy, J. , Vincent, I. , Van Der Hooft, J. J.J. , Rogers, S. , Burgess, K. and Daly, R. (2021) Ranking metabolite sets by their activity levels. Metabolites, 11(2), 103. (doi: 10.3390/metabo11020103) (PMID:33670102) (PMCID:PMC7916825)

Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)

Pesko, B. K., Weidt, S., McLaughlin, M. , Wescott, D. J., Torrance, H., Burgess, K. and Burchmore, R. (2020) Post-mortomics: the potential of untargeted metabolomics to highlight markers for time since death. OMICS: A Journal of Integrative Biology, 24(11), pp. 649-659. (doi: 10.1089/omi.2020.0084) (PMID:33095683)

Blackburn, G. et al. (2020) Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest. Metabolites, 10(10), 399. (doi: 10.3390/metabo10100399) (PMID:33050077) (PMCID:PMC7600507)

Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)

Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)

Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)

Burgon, J. D. , Vieites, D. R., Jacobs, A. , Weidt, S. K., Gunter, H. M., Steinfartz, S., Burgess, K., Marble, B. K. and Elmer, K. R. (2020) Functional colour genes and signals of selection in colour polymorphic salamanders. Molecular Ecology, 29(7), pp. 1284-1299. (doi: 10.1111/mec.15411) (PMID:32159878)

Buckley, J., Daly, R. , Cobbold, C. A. , Burgess, K. and Mable, B. K. (2019) Changing environments and genetic variation: natural variation in inbreeding does not compromise short-term physiological responses. Proceedings of the Royal Society of London Series B: Biological Sciences, 286(1915), 20192109. (doi: 10.1098/rspb.2019.2109) (PMID:31744436) (PMCID:PMC6892046)

Vargas, D. A., Prieto, M. D., Martínez-Valencia, A. J., Cossio, A., Burgess, K. E.V., Burchmore, R. J.S. and Gómez, M. A. (2019) Pharmacometabolomics of meglumine antimoniate in patients with cutaneous leishmaniasis. Frontiers in Pharmacology, 10, 657. (doi: 10.3389/fphar.2019.00657) (PMID:31281253) (PMCID:PMC6595045)

Rankin, N. J. , Burgess, K., Weidt, S., Wannamethee, G., Sattar, N. and Welsh, P. (2019) High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry. Annals of Clinical Biochemistry, 56(3), pp. 397-407. (doi: 10.1177/0004563219830432) (PMID:30832481) (PMCID:PMC6498755)

van der Hooft, J. J.J., Alghefari, W., Watson, E., Everest, P. , Morton, F. R. , Burgess, K. E.V. and Smith, D. G.E. (2018) Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose. Metabolomics, 14(11), 144. (doi: 10.1007/s11306-018-1438-5) (PMID:30830405) (PMCID:PMC6208705)

Megalios, A., Daly, R. and Burgess, K. (2018) MetaboCraft: building a Minecraft plugin for metabolomics. Bioinformatics, 34(15), pp. 2693-2694. (doi: 10.1093/bioinformatics/bty102) (PMID:29608638) (PMCID:PMC6061834)

Newton, J., Ramage, G. , Gadegaard, N. , Zachs, W., Rogers, S. , Barrett, M. P. , Carruthers, G. and Burgess, K. (2018) Minimally-destructive atmospheric ionisation mass spectrometry authenticates authorship of historical manuscripts. Scientific Reports, 8, 10944. (doi: 10.1038/s41598-018-28810-2) (PMID:30050048) (PMCID:PMC6062563)

Burgess, K.E.V., Borutzki, Y., Rankin, N. , Daly, R. and Jourdan, S. (2017) MetaNetter 2: a Cytoscape plugin for ab initio network analysis and metabolite feature classification. Journal of Chromatography B, 1071, pp. 68-74. (doi: 10.1016/j.jchromb.2017.08.015) (PMID:29030098) (PMCID:PMC5726607)

Gloaguen, Y. , Morton, F. , Daly, R. , Gurden, R., Rogers, S. , Wandy, J. , Wilson, D., Barrett, M. and Burgess, K. (2017) PiMP my metabolome: An integrated, web-based tool for LC-MS metabolomics data. Bioinformatics, 33(24), pp. 4007-4009. (doi: 10.1093/bioinformatics/btx499) (PMID:28961954) (PMCID:PMC5860087)

Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)

Zambelloni, R., Connolly, J. P.R., Huerta Uribe, A. , Burgess, K., Marquez, R. and Roe, A. J. (2017) Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition. Molecular Microbiology, 105(4), pp. 606-619. (doi: 10.1111/mmi.13719) (PMID:28557017) (PMCID:PMC5575525)

Alakpa, E. V., Jayawarna, V., Burgess, K. E.V., West, C. C., Péault, B., Ulijn, R. V. and Dalby, M. J. (2017) Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels. Scientific Reports, 7, 6895. (doi: 10.1038/s41598-017-07255-z) (PMID:28761049) (PMCID:PMC5537289)

Alakpa, E. V., Burgess, K. E.V., Chung, P., Riehle, M. O. , Gadegaard, N. , Dalby, M. J. and Cusack, M. (2017) Nacre topography produces higher crystallinity in bone than chemically induced osteogenesis. ACS Nano, 11(7), pp. 6717-6727. (doi: 10.1021/acsnano.7b01044) (PMID:28665112)

van der Hooft, J. J.J. , Wandy, J. , Young, F., Padmanabhan, S. , Gerasimidis, K. , Burgess, K. E.V., Barrett, M. P. and Rogers, S. (2017) Unsupervised discovery and comparison of structural families across multiple samples in untargeted metabolomics. Analytical Chemistry, 89(14), pp. 7569-7577. (doi: 10.1021/acs.analchem.7b01391) (PMID:28621528) (PMCID:PMC5524435)

Mwenechanya, R. et al. (2017) Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. PLoS Neglected Tropical Diseases, 11(6), e0005649. (doi: 10.1371/journal.pntd.0005649) (PMID:28622334) (PMCID:PMC5498063)

Kean, R. et al. (2017) Candida albicans mycofilms support Staphylococcus aureus colonization and enhances miconazole resistance in dual-species interactions. Frontiers in Microbiology, 8, 258. (doi: 10.3389/fmicb.2017.00258)

Akpunarlieva, S., Weidt, S., Lamasudin, D., Naula, C. , Henderson, D., Barrett, M. , Burgess, K. and Burchmore, R. (2017) Integration of proteomics and metabolomics to elucidate metabolic adaptation in Leishmania. Journal of Proteomics, 155, pp. 85-98. (doi: 10.1016/j.jprot.2016.12.009) (PMID:28040509)

Haggarty, J. and Burgess, K. E.V. (2017) Recent advances in liquid and gas chromatography methodology for extending coverage of the metabolome. Current Opinion in Biotechnology, 43, pp. 77-85. (doi: 10.1016/j.copbio.2016.09.006) (PMID:27771607)

Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)

Weidt, S., Haggarty, J., Kean, R., Cojocariu, C. I., Silcock, P. J., Rajendran, R., Ramage, G. and Burgess, K. E. V. (2016) A novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms. Metabolomics, 12, 189. (doi: 10.1007/s11306-016-1134-2) (PMID:28003796) (PMCID:PMC5097782)

van Der Hooft, J. J. J. , Wandy, J. , Barrett, M. P. , Burgess, K. E.V. and Rogers, S. (2016) Topic modeling for untargeted substructure exploration in metabolomics. Proceedings of the National Academy of Sciences of the United States of America, 113(48), pp. 13738-13743. (doi: 10.1073/pnas.1608041113) (PMID:27856765) (PMCID:PMC5137707)

Rajendran, R. et al. (2016) Integrating Candida albicans metabolism with biofilm heterogeneity by transcriptome mapping. Scientific Reports, 6, 35436. (doi: 10.1038/srep35436) (PMID:27765942) (PMCID:PMC5073228)

Thomas, F., Mudaliar, M. , Tassi, R., Mcneilly, T., Burchmore, R. , Burgess, K., Herzyk, P. , Zadoks, R. and Eckersall, P. (2016) Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 3. Untargeted metabolomics. Molecular BioSystems, 12(9), pp. 2762-2769. (doi: 10.1039/C6MB00289G) (PMID:27412568)

Alakpa, E. et al. (2016) Tunable supramolecular hydrogels for selection of lineage guiding metabolites in stem cell cultures. Chem, 1(2), pp. 298-319. (doi: 10.1016/j.chempr.2016.07.001)

Van Der Hooft, J. , Padmanabhan, S. , Burgess, K. and Barrett, M. (2016) Erratum to: Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12(8), 139. (doi: 10.1007/s11306-016-1078-6)

Roberts, J. N. et al. (2016) Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation. ACS Nano, 10(7), pp. 6667-6679. (doi: 10.1021/acsnano.6b01765) (PMID:27322014) (PMCID:PMC4963921)

Van Der Hooft, J. J.J. , Padmanabhan, S. , Burgess, K. E.V. and Barrett, M. P. (2016) Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation. Metabolomics, 12, 125. (doi: 10.1007/s11306-016-1064-z) (PMID:27471437) (PMCID:PMC4932139)

Stipetic, L. H., Dalby, M. J. , Davies, R. L. , Morton, F. r. , Ramage, G. and Burgess, K. (2016) A novel metabolomic approach used for the comparison of Staphylococcus aureus planktonic cells and biofilm samples. Metabolomics, 12, 75. (doi: 10.1007/s11306-016-1002-0) (PMID:27013931) (PMCID:PMC4783440)

Kim, D.-H., Achcar, F. , Breitling, R. , Burgess, K. E. and Barrett, M. P. (2015) LC–MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes. Metabolomics, 11(6), pp. 1721-1732. (doi: 10.1007/s11306-015-0827-2) (PMID:26491423) (PMCID:PMC4605981)

Haggarty, J., Oppermann, M., Dalby, M. J. , Burchmore, R. J. , Cook, K., Weidt, S. and Burgess, K. E.V. (2015) Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome. Metabolomics, 11(5), pp. 1465-1470. (doi: 10.1007/s11306-014-0770-7) (PMID:26366140) (PMCID:PMC4559102)

Stipetic, L. H., Hamilton, G., Dalby, M. J. , Davies, R. L. , Meek, R.M. D., Ramage, G. , Smith, D. G.E. and Burgess, K. E.V. (2015) Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip. Genome Announcements, 3(2), e00336-15. (doi: 10.1128/genomeA.00336-15) (PMID:25931597) (PMCID:PMC4417693)

Connolly, J. P.R., Goldstone, R. J., Burgess, K., Cogdell, R. J. , Beatson, S. A., Vollmer, W., Smith, D. G.E. and Roe, A. (2015) The host metabolite D-serine contributes to bacterial niche specificity through gene selection. ISME Journal, 9, pp. 1039-1051. (doi: 10.1038/ismej.2014.242) (PMID:25526369) (PMCID:PMC4366372)

Creek, D. J. et al. (2015) Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLoS Pathogens, 11(3), e1004689. (doi: 10.1371/journal.ppat.1004689) (PMID:25775470) (PMCID:PMC4361558)

van der Hooft, J. , Ridder, L., Barrett, M. P. and Burgess, K. V. (2015) Enhanced acylcarnitine annotation in high-resolution mass spectrometry data: fragmentation analysis for the classification and annotation of acylcarnitines. Frontiers in Bioengineering and Biotechnology, 3, p. 26. (doi: 10.3389/fbioe.2015.00026) (PMID:25806366) (PMCID:PMC4353373)

Alkhaldi, A.A.M., Creek, D.J., Ibrahim, H., Kim, D.-H., Quashie, N.B., Burgess, K.E., Changtam, C., Barrett, M.P. , Suksamrarn, A. and De Koning, H.P. (2015) Potent Trypanocidal curcumin analogs bearing a monoenone linker motif act on Trypanosoma brucei by forming an adduct with Trypanothione. Molecular Pharmacology, 87(3), pp. 451-464. (doi: 10.1124/mol.114.096016) (PMID:25527638)

McNamara, L. E., Turner, L.-A. and Burgess, K. V. (2015) Systems biology approaches applied to regenerative medicine. Current Pathobiology Reports, 3(1), pp. 37-45. (doi: 10.1007/s40139-015-0072-4) (PMID:25722955) (PMCID:PMC4333234)

Rankin, N. J. , Preiss, D. , Welsh, P. , Burgess, K. E.V., Nelson, S. M. , Lawlor, D. A. and Sattar, N. (2014) The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective. Atherosclerosis, 237(1), pp. 287-300. (doi: 10.1016/j.atherosclerosis.2014.09.024) (PMID:25299963) (PMCID:PMC4232363)

Yang, J., McNamara, L. E., Gadegaard, N. , Alakpa, E. V., Burgess, K. V., Meek, D. and Dalby, M. J. (2014) Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs. ACS Nano, 8(10), pp. 9941-9953. (doi: 10.1021/nn504767g) (PMID:25227207)

Daly, R. , Rogers, S. , Wandy, J., Jankevics, A., Burgess, K. E.V. and Breitling, R. (2014) MetAssign: probabilistic annotation of metabolites from LC–MS data using a Bayesian clustering approach. Bioinformatics, 30(19), pp. 2764-2771. (doi: 10.1093/bioinformatics/btu370) (PMID:24916385) (PMCID:PMC4173012)

Evans, S., Burgess, K. E.V. and Gray, J. V. (2014) Recovery from Rapamycin: drug-insensitive activity of yeast target of rapamycin complex 1 (torc1) supports residual proliferation that dilutes rapamycin among progeny cells. Journal of Biological Chemistry, 289(38), pp. 26554-26565. (doi: 10.1074/jbc.M114.589754) (PMID:25104356) (PMCID:PMC4176226)

Beckham, K. S.H. et al. (2014) The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7. Molecular Microbiology, 93(1), pp. 199-211. (doi: 10.1111/mmi.12651) (PMID:24846743) (PMCID:PMC4249723)

Vincent, I. M. , Weidt, S., Rivas, L., Burgess, K., Smith, T. K. and Ouellette, M. (2014) Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism. International Journal for Parasitology: Drugs and Drug Resistance, 4(1), pp. 20-27. (doi: 10.1016/j.ijpddr.2013.11.002) (PMID:24596665) (PMCID:PMC3940234)

Tsimbouri, P. , Gadegaard, N., Burgess, K., White, K., Reynolds, P. , Herzyk, P. , Oreffo, R. and Dalby, M.J. (2014) Nanotopographical effects on mesenchymal stem cell morphology and phenotype. Journal of Cellular Biochemistry, 115(2), pp. 380-390. (doi: 10.1002/jcb.24673) (PMID:24123223)

Lipina, C., Macrae, K., Suhm, T., Weigert, C., Blachnio-Zabielska, A., Baranowski, M., Gorski, J., Burgess, K. and Hundal, H. S. (2013) Mitochondrial substrate availability and its role in lipid-induced insulin resistance and proinflammatory signaling in skeletal muscle. Diabetes, 62(10), pp. 3426-3436. (doi: 10.2337/db13-0264) (PMID:23733201) (PMCID:PMC3781443)

Rupp, A.F., Galban-Horcajo, F., Bianchi, E., Dondi, M., Penderis, J., Cappell, J., Burgess, K., Matiasek, K., McGonigal, R. and Willison, H.J. (2013) Anti-GM2 ganglioside antibodies are a biomarker for acute canine polyradiculoneuritis. Journal of the Peripheral Nervous System, 18(1), pp. 75-88. (doi: 10.1111/jns5.12011) (PMID:23521648)

Ali, J.A.M., Creek, D.J., Burgess, K., Allison, H.C., Field, M.C., Maser, P. and De Koning, H.P. (2013) Pyrimidine salvage in trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines. Molecular Pharmacology, 83(2), pp. 439-453. (doi: 10.1124/mol.112.082321) (PMID:23188714)

Seras-Franzoso, J., Tsimbouri, P.M. , Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J. (2013) Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces. Nanomedicine, 9(2), pp. 207-220. (doi: 10.2217/nnm.13.43) (PMID:23631503)

Tsimbouri, P.M. , McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, P. , Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N. and Dalby, M.J. (2012) Using nanotopography and metabolomics to identify biochemical effectors of multipotency. ACS Nano, 6(11), pp. 10239-10249. (doi: 10.1021/nn304046m)

Creek, D.J., Chokkathukalam, A., Jankevics, A., Burgess, K.E.V., Breitling, R. and Barrett, M.P. (2012) Stable isotope-assisted metabolomics for network-wide metabolic pathway elucidation. Analytical Chemistry, 84(20), pp. 8442-8447. (doi: 10.1021/ac3018795) (PMID:22946681) (PMCID:PMC3472505)

Burgess, K.E.V. and Burchmore, R.J.S. (2012) Strategies to dissect parasite proteomes. Parasitology, 139(9), pp. 1119-1130. (doi: 10.1017/S0031182011002368)

Lockman, K.A. et al. (2012) Oxidative stress rather than triglyceride accumulation is a determinant of mitochondrial dysfunction in in vitro models of hepatic cellular steatosis. Liver International, 32(7), pp. 1079-1092. (doi: 10.1111/j.1478-3231.2012.02775.x)

Creek, D.J., Jankevics, A., Burgess, K.E.V., Breitling, R. and Barrett, M.P. (2012) IDEOM: an excel interface for analysis of LC-MS based metabolomics data. Bioinformatics, 28(7), pp. 1048-1049. (doi: 10.1093/bioinformatics/bts069) (PMID:22308147)

Alakpa, E., Jayarwarna, V., Burgess, K. and Dalby, M. (2012) Characterisation of peptide biomaterials & innate metabolites that direct stem cell differentiation in vitro. European Cell and Materials, 23(Sup 4), p. 50.

Vincent, I.M. , Creek, D.J., Burgess, K., Woods, D.J., Burchmore, R.J.S. and Barrett, M.P. (2012) Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against trypanosoma brucei. PLoS Neglected Tropical Diseases, 6(5), e1618. (doi: 10.1371/journal.pntd.0001618) (PMID:22563508) (PMCID:PMC3341325)

Burgess, K., Creek, D., Dewsbury, P., Cook, K. and Barrett, M.P. (2011) Semi-targeted analysis of metabolites using capillary-flow ion chromatography coupled to high-resolution mass spectrometry. Rapid Communications in Mass Spectrometry, 25(22), pp. 3447-3452. (doi: 10.1002/rcm.5247)

Leader, D.P. , Burgess, K., Creek, D. and Barrett, M.P. (2011) Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry. Rapid Communications in Mass Spectrometry, 25(22), pp. 3422-3426. (doi: 10.1002/rcm.5245)

McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)

McMurray, R.J., Gadegaard, N. , Tsimbouri, P.M. , Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nature Materials, 10(8), pp. 637-644. (doi: 10.1038/nmat3058) (PMID:21765399)

Alakpa, E., Jayawarna, V., Burgess, K. and Dalby, M. (2011) Elucidating cellular reaction to biomaterial substrates using a metabolomics approach. European Cells and Materials, 22(Sup 3), p. 18.

Creek, D.J., Jankevics, A., Breitling, R. , Watson, D.G., Barrett, M.P. and Burgess, K.E.V. (2011) Toward global metabolomics snalysis with Hydrophilic Interaction Liquid Chromatography–Mass Spectrometry: improved metabolite identification by retention time prediction. Analytical Chemistry, 83(22), pp. 8703-8710. (doi: 10.1021/ac2021823)

Tsimbouri, P. , Gadegaard, N. , Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography. Histology and Histopathology: Cellular and Molecular Biology, 26(S1), 31.012.

Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Riehle, M.O. , Oreffo, R.O., Dalby, M.J. and Burchmore, R. (2010) Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells. Acta Biomaterialia, 6(9), pp. 3694-3703. (doi: 10.1016/j.actbio.2010.02.038)

Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Burchmore, R.J. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling. Biomaterials, 30(27), pp. 4723-4731. (doi: 10.1016/j.biomaterials.2009.05.040)

Book Sections

Burgess, K., Rankin, N. and Weidt, S. (2014) Metabolomics. In: Padmanabhan, S. (ed.) Handbook of Pharmacogenomics and Stratified Medicine. Academic Press: London, pp. 181-205. ISBN 9780123868824 (doi: 10.1016/B978-0-12-386882-4.00010-4)

Conference or Workshop Item

Alakpa, E., Burgess, K., Chung, P., Dalby, M. and Cusack, M. (2015) Topographical Bridging Between Bone and Nacre. International Society for Stem Cell Research (ISSCR), Stockholm, Sweden, 24-27th Jun 2015.

Alakpa, E., Burgess, K., Dalby, M. and Cusack, M. (2014) Investigating the 'Bone-Shell Divide': Pearl Oyster Shell Topography as a Means of Directing Stem Cell Behaviour. European Society for Biomaterials (ESB 2014), Liverpool, UK, 31st Aug–3rd Sep 2014. (Unpublished)

Alakpa, E., Jayawarna, V., Burgess, K., Ulijn, R. and Dalby, M. (2013) Combining Hydrogels With Tuned Stiffness and Metabolomics to Identify Small Molecules that Drive Mesenchymal Stem Cell Differentiation. European Materials Research Society (E-MRS), Strasbourg, France, 27-31 May 2013.

Alakpa, E.V., Burgess, K., Jayawarna, V., Ulijn, R. and Dalby, M. (2012) Development of Biomaterials for Cellular Differentiation Using a Metabolomics Approach. 3rd TERMIS World Congress, Vienna, Austria, 5-8 Sep 2012. p. 238.