2024

Hargrave, K. E., Worrell, J. C. , Pirillo, C., Brennan, E., Masdefiol Garriga, A. , Gray, J. I., Purnell, T., Roberts, E. W. and MacLeod, M. K.L. (2024) Lung influenza virus specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells. Mucosal Immunology, 17(5), pp. 843-857. (doi: 10.1016/j.mucimm.2024.06.001) (PMID:38851589)

2023

Pinto, R. M. et al. (2023) BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature, 619(7969), pp. 338-347. (doi: 10.1038/s41586-023-06261-8) (PMID:37380775)

Finney, G. E., Hargrave, K. E., Pingen, M. , Purnell, T., Todd, D., MacDonald, F., Worrell, J. C. and Macleod, M. K.L. (2023) Triphasic production of IFNγ by innate and adaptive lymphocytes following influenza A virus infection. Discovery Immunology, 2(1), kyad014. (doi: 10.1093/discim/kyad014) (PMID:37842651) (PMCID:PMC10568397)

2022

Hargrave, K. E., MacLeod, M. K.L. and Worrell, J. C. (2022) Antigen presenting cells: professionals, amateurs, and spectators in the 'long game' of lung immunity. International Journal of Biochemistry and Cell Biology, 153, 106331. (doi: 10.1016/j.biocel.2022.106331) (PMID:36368596)

2021

Worrell, J. C. and MacLeod, M. K.L. (2021) Stromal‐immune cell cross talk fundamentally alters the lung microenvironment following tissue insult. Immunology, 163(3), pp. 239-249. (doi: 10.1111/imm.13319) (PMID:33556186) (PMCID:PMC8014587)

2020

Worrell, J. C. et al. (2020) cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis. Rheumatology, 59(12), pp. 3939-3951. (doi: 10.1093/rheumatology/keaa272) (PMID:32725139)

Worrell, J. C. , Walsh, S. M., Fabre, A., Kane, R., Hinz, B. and Keane, M. P. (2020) CXCR3A promotes the secretion of the anti-fibrotic decoy receptor sIL-13Rα2 by pulmonary fibroblasts. American Journal of Physiology: Cell Physiology, 319(6), C1059-C1069. (doi: 10.1152/ajpcell.00076.2020) (PMID:33026833)

Leslie, J. et al. (2020) c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis. Nature Metabolism, 2, pp. 1350-1367. (doi: 10.1038/s42255-020-00306-2) (PMID:33168981) (PMCID:PMC7116435)

Worrell, J. C. and O'Reilly, S. (2020) Bi-directional communication: Conversations between fibroblasts and immune cells in systemic sclerosis. Journal of Autoimmunity, 113, 102526. (doi: 10.1016/j.jaut.2020.102526) (PMID:32713676)

2018

Henderson, J., Brown, M., Horsburgh, S., Duffy, L., Wilkinson, S., Worrell, J. , Stratton, R. and O’Reilly, S. (2018) Methyl cap binding protein 2: a key epigenetic protein in systemic sclerosis. Rheumatology, 58(3), pp. 527-535. (doi: 10.1093/rheumatology/key327) (PMID:30462328)

Walsh, S. M., Worrell, J. C. , Fabre, A., Hinz, B., Kane, R. and Keane, M. P. (2018) Novel differences in gene expression and functional capabilities of myofibroblast populations in idiopathic pulmonary fibrosis. American Journal of Physiology: Lung Cellular and Molecular Physiology, 315(5), L697-L710. (doi: 10.1152/ajplung.00543.2017) (PMID:30091381)

Cartwright, T. N., Worrell, J. C. , Marchetti, L., Dowling, C. M., Knox, A., Kiely, P., Mann, J., Mann, D. A. and Wilson, C. L. (2018) HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression. Biochimica et Biophysica Acta: Gene Regulatory Mechanisms, 1861(10), pp. 962-970. (doi: 10.1016/j.bbagrm.2018.09.001) (PMID:30496041)

2015

O’Beirne, S. L. et al. (2015) CXCL9 regulates TGF-β1–induced epithelial to mesenchymal transition in human alveolar epithelial cells. Journal of Immunology, 195(6), pp. 2788-2796. (doi: 10.4049/jimmunol.1402008) (PMID:26268659) (PMCID:PMC4777321)

Barnes, J. C. et al. (2015) CXCR3 requirement for the interleukin-13–mediated up-regulation of interleukin-13Rα2 in pulmonary fibroblasts. American Journal of Respiratory Cell and Molecular Biology, 53(2), pp. 217-225. (doi: 10.1165/rcmb.2013-0433OC) (PMID:25514189) (PMCID:PMC5455693)

Lumsden, R. V. et al. (2015) Modulation of pulmonary fibrosis by IL-13Rα2. American Journal of Physiology: Lung Cellular and Molecular Physiology, 308(7), L710-L718. (doi: 10.1152/ajplung.00120.2014) (PMID:25659898)

Articles

Hargrave, K. E., Worrell, J. C. , Pirillo, C., Brennan, E., Masdefiol Garriga, A. , Gray, J. I., Purnell, T., Roberts, E. W. and MacLeod, M. K.L. (2024) Lung influenza virus specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells. Mucosal Immunology, 17(5), pp. 843-857. (doi: 10.1016/j.mucimm.2024.06.001) (PMID:38851589)

Pinto, R. M. et al. (2023) BTN3A3 evasion promotes the zoonotic potential of influenza A viruses. Nature, 619(7969), pp. 338-347. (doi: 10.1038/s41586-023-06261-8) (PMID:37380775)

Finney, G. E., Hargrave, K. E., Pingen, M. , Purnell, T., Todd, D., MacDonald, F., Worrell, J. C. and Macleod, M. K.L. (2023) Triphasic production of IFNγ by innate and adaptive lymphocytes following influenza A virus infection. Discovery Immunology, 2(1), kyad014. (doi: 10.1093/discim/kyad014) (PMID:37842651) (PMCID:PMC10568397)

Hargrave, K. E., MacLeod, M. K.L. and Worrell, J. C. (2022) Antigen presenting cells: professionals, amateurs, and spectators in the 'long game' of lung immunity. International Journal of Biochemistry and Cell Biology, 153, 106331. (doi: 10.1016/j.biocel.2022.106331) (PMID:36368596)

Worrell, J. C. and MacLeod, M. K.L. (2021) Stromal‐immune cell cross talk fundamentally alters the lung microenvironment following tissue insult. Immunology, 163(3), pp. 239-249. (doi: 10.1111/imm.13319) (PMID:33556186) (PMCID:PMC8014587)

Worrell, J. C. et al. (2020) cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis. Rheumatology, 59(12), pp. 3939-3951. (doi: 10.1093/rheumatology/keaa272) (PMID:32725139)

Worrell, J. C. , Walsh, S. M., Fabre, A., Kane, R., Hinz, B. and Keane, M. P. (2020) CXCR3A promotes the secretion of the anti-fibrotic decoy receptor sIL-13Rα2 by pulmonary fibroblasts. American Journal of Physiology: Cell Physiology, 319(6), C1059-C1069. (doi: 10.1152/ajpcell.00076.2020) (PMID:33026833)

Leslie, J. et al. (2020) c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis. Nature Metabolism, 2, pp. 1350-1367. (doi: 10.1038/s42255-020-00306-2) (PMID:33168981) (PMCID:PMC7116435)

Worrell, J. C. and O'Reilly, S. (2020) Bi-directional communication: Conversations between fibroblasts and immune cells in systemic sclerosis. Journal of Autoimmunity, 113, 102526. (doi: 10.1016/j.jaut.2020.102526) (PMID:32713676)

Henderson, J., Brown, M., Horsburgh, S., Duffy, L., Wilkinson, S., Worrell, J. , Stratton, R. and O’Reilly, S. (2018) Methyl cap binding protein 2: a key epigenetic protein in systemic sclerosis. Rheumatology, 58(3), pp. 527-535. (doi: 10.1093/rheumatology/key327) (PMID:30462328)

Walsh, S. M., Worrell, J. C. , Fabre, A., Hinz, B., Kane, R. and Keane, M. P. (2018) Novel differences in gene expression and functional capabilities of myofibroblast populations in idiopathic pulmonary fibrosis. American Journal of Physiology: Lung Cellular and Molecular Physiology, 315(5), L697-L710. (doi: 10.1152/ajplung.00543.2017) (PMID:30091381)

Cartwright, T. N., Worrell, J. C. , Marchetti, L., Dowling, C. M., Knox, A., Kiely, P., Mann, J., Mann, D. A. and Wilson, C. L. (2018) HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression. Biochimica et Biophysica Acta: Gene Regulatory Mechanisms, 1861(10), pp. 962-970. (doi: 10.1016/j.bbagrm.2018.09.001) (PMID:30496041)

O’Beirne, S. L. et al. (2015) CXCL9 regulates TGF-β1–induced epithelial to mesenchymal transition in human alveolar epithelial cells. Journal of Immunology, 195(6), pp. 2788-2796. (doi: 10.4049/jimmunol.1402008) (PMID:26268659) (PMCID:PMC4777321)

Barnes, J. C. et al. (2015) CXCR3 requirement for the interleukin-13–mediated up-regulation of interleukin-13Rα2 in pulmonary fibroblasts. American Journal of Respiratory Cell and Molecular Biology, 53(2), pp. 217-225. (doi: 10.1165/rcmb.2013-0433OC) (PMID:25514189) (PMCID:PMC5455693)

Lumsden, R. V. et al. (2015) Modulation of pulmonary fibrosis by IL-13Rα2. American Journal of Physiology: Lung Cellular and Molecular Physiology, 308(7), L710-L718. (doi: 10.1152/ajplung.00120.2014) (PMID:25659898)