Research interests

Combining Experimental Virology and Artificial Intelligence

In the Grove Lab, we harness cutting-edge artificial intelligence alongside classical experimental virology to investigate the structure, function and evolution of viral proteins. Our focus is viral entry glycoproteins, but our combined computational and experimental approach is broadly applicable across molecular virology.

 

AI-Enabled Discovery

Artificial intelligence is revolutionising molecular virology, enabling us to predict viral protein structures, infer evolutionary relationships, and identify novel targets for vaccines or therapies. Our AI-driven research includes:

• Viro3D: A comprehensive database of virus protein structure predictions. >4,400 human and animal viruses, >85,000 structural models predicted using AlphaFold and ESMFold.

• A structural perspective on evolution: Mapping glycoprotein structures to reveal deep evolutionary relationships and novel fusion mechanisms.

• Revealing mechanism: Using predicted structures to investigate protein function, helping to characterise viral proteins with previously unknown mechanisms.

 

Good-old-fashioned Experimental Virology

Experimental virology research grounds our computational predictions in real-world biology. We apply a range of classical virological techniques to explore viral entry, host interactions, and evolution. Our investigations focus on:

• Evolution and Adaptation: Exploring how viral proteins evolve to adapt to host and evade immune responses, and how this relates to glycoprotein structure and function.

• Fundamentals of Virus Entry: Investigating how the structure and dynamics of viral glycoproteins relate to receptor interactions and function.

 

For more information about our research, publications, and team, please visit the Grove Lab website.

 

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2014 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007
Number of items: 40.

2025

Lytras, S., Lamb, K. D., Ito, J., Grove, J. , Yuan, K. , Sato, K., Hughes, J. and Robertson, D. L. (2025) Pathogen genomic surveillance and the AI revolution. Journal of Virology, 99(2), e0160124. (doi: 10.1128/jvi.01601-24) (PMID:39878472) (PMCID:39878472)

Furnon, W. et al. (2025) Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic. Nature Microbiology, 10, pp. 77-93. (doi: 10.1038/s41564-024-01878-5) (PMID:39753670) (PMCID:PMC11726466)

2024

Lamb, K. D., Hughes, J. , Lytras, S., Young, F., Koci, O., Herzig, J., Lovell, S. C.,, Grove, J. , Yuan, K. and Robertson, D. L. (2024) From a single sequence to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2 protein sequences. bioRxiv, (doi: 10.1101/2024.07.05.602129)

Mifsud, J. C.O., Lytras, S., Oliver, M. R. , Toon, K. , Costa, V. A., Holmes, E. C. and Grove, J. (2024) Mapping glycoprotein structure reveals Flaviviridae evolutionary history. Nature, 633(8030), pp. 695-703. (doi: 10.1038/s41586-024-07899-8) (PMID:39232167)

Mifsud, J. C.O., Lytras, S., Oliver, M. R. , Toon, K. , Costa, V. A., Holmes, E. C. and Grove, J. (2024) Mapping glycoprotein structure reveals defining events in the evolution of the Flaviviridae. bioRxiv, (doi: 10.1101/2024.02.06.579159)

Petrone, M. E., Grove, J. , Mifsud, J. C. O., Parry, R. H., Marzinelli, E. M. and Holmes, E. C. (2024) A 39.8kb flavi-like virus uses a novel strategy for overcoming the RNA virus error threshold. bioRxiv, (doi: 10.1101/2024.01.08.574764)

2023

Skeldon, K. et al. (2023) Research Firsts Exhibition. [Exhibitions]

Willett, B. J. et al. (2023) Omicron BA.2.86 cross-neutralising activity in community sera from the UK. Lancet, 402(10417), pp. 2075-2076. (doi: 10.1016/s0140-6736(23)02397-8) (PMID:37952549)

Styles, C. T. et al. (2023) Propylene glycol inactivates respiratory viruses and prevents airborne transmission. EMBO Molecular Medicine, 15(12), e17932. (doi: 10.15252/emmm.202317932) (PMID:37970627) (PMCID:PMC10701621)

Toon, K. , Kalemera, M. D., Palor, M., Rose, N. J., Takeuchi, Y., Grove, J. and Mattiuzzo, G. (2023) GB Virus B and Hepatitis C Virus, distantly related Hepaciviruses, share an entry factor, Claudin-1. Journal of Virology, 97(7), e00469-23. (doi: 10.1128/jvi.00469-23) (PMID:37310242) (PMCID:PMC10373534)

Oliver, M. R. , Toon, K. , Lewis, C. B., Devlin, S., Gifford, R. J. and Grove, J. (2023) Structures of the Hepaci-, Pegi-, and Pestiviruses envelope proteins suggest a novel membrane fusion mechanism. PLoS Biology, 21(7), e3002174. (doi: 10.1371/journal.pbio.3002174) (PMID:37432947) (PMCID:PMC10335668)

Cantoni, D. and Grove, J. (2023) Low hanging fruit for combatting SARS‐CoV‐2? EMBO Reports, 24(4), e56979. (doi: 10.15252/embr.202356979) (PMID:36876512) (PMCID:PMC10074046)

2022

Mersmann, S. F., Johns, E., Yong, T., McEwan, W. A., James, L. C., Cohen, E. A.K. and Grove, J. (2022) A novel and robust method for counting components within bio-molecular complexes using fluorescence microscopy and statistical modelling. Scientific Reports, 12, 17286. (doi: 10.1038/s41598-022-20506-y) (PMID:36241663) (PMCID:PMC9568568)

Cantoni, D. et al. (2022) Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike. EMBO Reports, 23(10), e54322. (doi: 10.15252/embr.202154322) (PMID:35999696) (PMCID:PMC9535765)

Willett, B. J. et al. (2022) Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology, 7, 1709. (doi: 10.1038/s41564-022-01241-6) (PMID:36114232) (PMCID:PMC9483304)

Willett, B. J. et al. (2022) SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology, 7(8), pp. 1161-1179. (doi: 10.1038/s41564-022-01143-7) (PMID:35798890) (PMCID:PMC9352574)

Stejskal, L. et al. (2022) An entropic safety catch controls Hepatitis C virus entry and antibody resistance. eLife, 11, e71854. (doi: 10.7554/eLife.71854) (PMID:35796426) (PMCID:PMC9333995)

2021

Schmidt, N. M. et al. (2021) Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint. Nature Communications, 12, 2814. (doi: 10.1038/s41467-021-22967-7) (PMID:33990561) (PMCID:PMC8121939)

Kalemera, M. D., Capella-Pujol, J., Chumbe, A., Underwood, A., Bull, R. A., Schinkel, J., Sliepen, K. and Grove, J. (2021) Optimized cell systems for the investigation of hepatitis C virus E1E2 glycoproteins. Journal of General Virology, 102(1), 001512. (doi: 10.1099/jgv.0.001512) (PMID:33147126) (PMCID:PMC8116788)

2020

Palor, M. et al. (2020) Cholesterol sensing by CD81 is important for hepatitis C virus entry. Journal of Biological Chemistry, 295(50), pp. 16931-16948. (doi: 10.1074/jbc.RA120.014761) (PMID:32900848) (PMCID:PMC7863897)

Stejskal, L., Lees, W. D., Moss, D. S., Palor, M., Bingham, R. J., Shepherd, A. J. and Grove, J. (2020) Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein. PLoS Computational Biology, 16(2), e1007710. (doi: 10.1371/journal.pcbi.1007710) (PMID:32109245) (PMCID:PMC7065822)

2019

Davies, S. P. et al. (2019) Hepatocytes delete regulatory T cells by enclysis, a CD4+ T cell engulfment process. Cell Reports, 29(6), 1610-1620.e4. (doi: 10.1016/j.celrep.2019.09.068) (PMID:31693899) (PMCID:PMC7057271)

Mazzon, M. et al. (2019) Identification of broad-spectrum antiviral compounds by targeting viral entry. Viruses, 11(2), 176. (doi: 10.3390/v11020176) (PMID:30791609) (PMCID:PMC6410080)

2018

pereira, P. M., Jacobs, C. and Grove, J. (2018) Investigating hepatitis C virus infection using super-resolution microscopy. In: Law, Mansun (ed.) Hepatitis C Virus Protocols. Series: Methods in molecular biology (1911). Humana Press: New York, NY, pp. 247-261. ISBN 9781493989751 (doi: 10.1007/978-1-4939-8976-8_17)

2017

Grove, J. , Hu, K., Farquhar, M. J., Goodall, M., Walker, L., Jamshad, M., Drummer, H. E., Bill, R. M., Balfe, P. and McKeating, J. A. (2017) A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81. Wellcome Open Research, 2, 82. (doi: 10.12688/wellcomeopenres.12058.1) (PMID:29090272) (PMCID:PMC5657224)

Lythgoe, K. A., Gardner, A., Pybus, O. G. and Grove, J. (2017) Short-sighted virus evolution and a germline hypothesis for chronic viral infections. Trends in Microbiology, 25(5), pp. 336-348. (doi: 10.1016/j.tim.2017.03.003) (PMID:28377208) (PMCID:PMC5405858)

2016

Culley, S., Towers, G. J., Selwood, D. L., Henriques, R. and Grove, J. (2016) Infection counter: automated quantification of in vitro virus replication by fluorescence microscopy. Viruses, 8(7), 201. (doi: 10.3390/v8070201) (PMID:27455304) (PMCID:PMC4974536)

2014

Grove, J. , Metcalf, D. J., Knight, A. E., Wavre-Shapton, S. T., Sun, T., Protonotarios, E. D., Griffin, L. D., Lippincott-Schwartz, J. and Marsh, M. (2014) Flat clathrin lattices: stable features of the plasma membrane. Molecular Biology of the Cell, 25(22), pp. 3581-3594. (doi: 10.1091/mbc.E14-06-1154) (PMID:25165141) (PMCID:PMC4230618)

Grove, J. (2014) Super-resolution microscopy: a virus' eye view of the cell. Viruses, 6(3), pp. 1365-1378. (doi: 10.3390/v6031365) (PMID:24651030) (PMCID:PMC3970155)

2012

Henry, A. G., Hislop, J. N., Grove, J. , Thorn, K., Marsh, M. and von Zastrow, M. (2012) Regulation of endocytic clathrin dynamics by cargo ubiquitination. Developmental Cell, 23(3), pp. 519-532. (doi: 10.1016/j.devcel.2012.08.003) (PMID:22940114) (PMCID:PMC3470869)

2011

Grove, J. and Marsh, M. (2011) The cell biology of receptor-mediated virus entry. Journal of Cell Biology, 195(7), pp. 1071-1082. (doi: 10.1083/jcb.201108131) (PMID:22123832) (PMCID:PMC3246895)

Brimacombe, C. L. et al. (2011) Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission. Journal of Virology, 85(1), pp. 596-605. (doi: 10.1128/JVI.01592-10) (PMID:20962076) (PMCID:PMC3014195)

Syder, A. J. et al. (2011) Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors. Journal of Hepatology, 54(1), pp. 48-55. (doi: 10.1016/j.jhep.2010.06.024) (PMID:20932595)

2010

Wagoner, J. et al. (2010) Multiple effects of silymarin on the hepatitis C virus lifecycle. Hepatology, 51(6), pp. 1912-1921. (doi: 10.1002/hep.23587) (PMID:20512985) (PMCID:PMC2909978)

2009

Schwarz, A.K., Grove, J. , Hu, K., Mee, C.J., Balfe, P. and McKeating, J.A. (2009) Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. Journal of Virology, 83(23), pp. 12407-12414. (doi: 10.1128/JVI.01552-09) (PMID:19776133) (PMCID:PMC2786758)

2008

Stamataki, Z., Grove, J. , Balfe, P. and McKeating, J.A. (2008) Hepatitis C virus entry and neutralization. Clinics in Liver Disease, 12(3), pp. 693-712. (doi: 10.1016/j.cld.2008.03.008) (PMID:18625435)

Grove, J. , Nielsen, S., Zhong, J., Bassendine, M.F., Drummer, H.E., Balfe, P. and McKeating, J.A. (2008) Identification of a residue in hepatitis C virus E2 glycoprotein that determines scavenger receptor BI and CD81 receptor dependency and sensitivity to neutralizing antibodies. Journal of Virology, 82(24), pp. 12020-12029. (doi: 10.1128/JVI.01569-08) (PMID:18829747) (PMCID:PMC2593310)

Mee, C.J., Grove, J. , Harris, H.J., Hu, K., Balfe, P. and McKeating, J.A. (2008) Effect of cell polarization on hepatitis C virus entry. Journal of Virology, 82(1), pp. 461-470. (doi: 10.1128/JVI.01894-07) (PMID:17959672) (PMCID:PMC2224355)

Reynolds, G.M., Harris, H.J., Jennings, A., Hu, K., Grove, J. , Lalor, P.F., Adams, D.H., Balfe, P., Hübscher, S.G. and McKeating, J.A. (2008) Hepatitis C virus receptor expression in normal and diseased liver tissue. Hepatology, 47(2), pp. 418-427. (doi: 10.1002/hep.22028) (PMID:18085708)

2007

Williams, J.M., Pettitt, T.R., Powell, W., Grove, J. , Savage, C.O.S. and Wakelam, M.J.O. (2007) Antineutrophil cytoplasm antibody-stimulated neutrophil adhesion depends on diacylglycerol kinase-catalyzed phosphatidic acid formation. Journal of the American Society of Nephrology, 18(4), pp. 1112-1120. (doi: 10.1681/ASN.2006090973) (PMID:17360949)

This list was generated on Fri Mar 28 01:25:34 2025 GMT.
Jump to: Articles | Book Sections | Exhibitions
Number of items: 40.

Articles

Lytras, S., Lamb, K. D., Ito, J., Grove, J. , Yuan, K. , Sato, K., Hughes, J. and Robertson, D. L. (2025) Pathogen genomic surveillance and the AI revolution. Journal of Virology, 99(2), e0160124. (doi: 10.1128/jvi.01601-24) (PMID:39878472) (PMCID:39878472)

Furnon, W. et al. (2025) Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic. Nature Microbiology, 10, pp. 77-93. (doi: 10.1038/s41564-024-01878-5) (PMID:39753670) (PMCID:PMC11726466)

Lamb, K. D., Hughes, J. , Lytras, S., Young, F., Koci, O., Herzig, J., Lovell, S. C.,, Grove, J. , Yuan, K. and Robertson, D. L. (2024) From a single sequence to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2 protein sequences. bioRxiv, (doi: 10.1101/2024.07.05.602129)

Mifsud, J. C.O., Lytras, S., Oliver, M. R. , Toon, K. , Costa, V. A., Holmes, E. C. and Grove, J. (2024) Mapping glycoprotein structure reveals Flaviviridae evolutionary history. Nature, 633(8030), pp. 695-703. (doi: 10.1038/s41586-024-07899-8) (PMID:39232167)

Mifsud, J. C.O., Lytras, S., Oliver, M. R. , Toon, K. , Costa, V. A., Holmes, E. C. and Grove, J. (2024) Mapping glycoprotein structure reveals defining events in the evolution of the Flaviviridae. bioRxiv, (doi: 10.1101/2024.02.06.579159)

Petrone, M. E., Grove, J. , Mifsud, J. C. O., Parry, R. H., Marzinelli, E. M. and Holmes, E. C. (2024) A 39.8kb flavi-like virus uses a novel strategy for overcoming the RNA virus error threshold. bioRxiv, (doi: 10.1101/2024.01.08.574764)

Willett, B. J. et al. (2023) Omicron BA.2.86 cross-neutralising activity in community sera from the UK. Lancet, 402(10417), pp. 2075-2076. (doi: 10.1016/s0140-6736(23)02397-8) (PMID:37952549)

Styles, C. T. et al. (2023) Propylene glycol inactivates respiratory viruses and prevents airborne transmission. EMBO Molecular Medicine, 15(12), e17932. (doi: 10.15252/emmm.202317932) (PMID:37970627) (PMCID:PMC10701621)

Toon, K. , Kalemera, M. D., Palor, M., Rose, N. J., Takeuchi, Y., Grove, J. and Mattiuzzo, G. (2023) GB Virus B and Hepatitis C Virus, distantly related Hepaciviruses, share an entry factor, Claudin-1. Journal of Virology, 97(7), e00469-23. (doi: 10.1128/jvi.00469-23) (PMID:37310242) (PMCID:PMC10373534)

Oliver, M. R. , Toon, K. , Lewis, C. B., Devlin, S., Gifford, R. J. and Grove, J. (2023) Structures of the Hepaci-, Pegi-, and Pestiviruses envelope proteins suggest a novel membrane fusion mechanism. PLoS Biology, 21(7), e3002174. (doi: 10.1371/journal.pbio.3002174) (PMID:37432947) (PMCID:PMC10335668)

Cantoni, D. and Grove, J. (2023) Low hanging fruit for combatting SARS‐CoV‐2? EMBO Reports, 24(4), e56979. (doi: 10.15252/embr.202356979) (PMID:36876512) (PMCID:PMC10074046)

Mersmann, S. F., Johns, E., Yong, T., McEwan, W. A., James, L. C., Cohen, E. A.K. and Grove, J. (2022) A novel and robust method for counting components within bio-molecular complexes using fluorescence microscopy and statistical modelling. Scientific Reports, 12, 17286. (doi: 10.1038/s41598-022-20506-y) (PMID:36241663) (PMCID:PMC9568568)

Cantoni, D. et al. (2022) Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike. EMBO Reports, 23(10), e54322. (doi: 10.15252/embr.202154322) (PMID:35999696) (PMCID:PMC9535765)

Willett, B. J. et al. (2022) Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology, 7, 1709. (doi: 10.1038/s41564-022-01241-6) (PMID:36114232) (PMCID:PMC9483304)

Willett, B. J. et al. (2022) SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology, 7(8), pp. 1161-1179. (doi: 10.1038/s41564-022-01143-7) (PMID:35798890) (PMCID:PMC9352574)

Stejskal, L. et al. (2022) An entropic safety catch controls Hepatitis C virus entry and antibody resistance. eLife, 11, e71854. (doi: 10.7554/eLife.71854) (PMID:35796426) (PMCID:PMC9333995)

Schmidt, N. M. et al. (2021) Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint. Nature Communications, 12, 2814. (doi: 10.1038/s41467-021-22967-7) (PMID:33990561) (PMCID:PMC8121939)

Kalemera, M. D., Capella-Pujol, J., Chumbe, A., Underwood, A., Bull, R. A., Schinkel, J., Sliepen, K. and Grove, J. (2021) Optimized cell systems for the investigation of hepatitis C virus E1E2 glycoproteins. Journal of General Virology, 102(1), 001512. (doi: 10.1099/jgv.0.001512) (PMID:33147126) (PMCID:PMC8116788)

Palor, M. et al. (2020) Cholesterol sensing by CD81 is important for hepatitis C virus entry. Journal of Biological Chemistry, 295(50), pp. 16931-16948. (doi: 10.1074/jbc.RA120.014761) (PMID:32900848) (PMCID:PMC7863897)

Stejskal, L., Lees, W. D., Moss, D. S., Palor, M., Bingham, R. J., Shepherd, A. J. and Grove, J. (2020) Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein. PLoS Computational Biology, 16(2), e1007710. (doi: 10.1371/journal.pcbi.1007710) (PMID:32109245) (PMCID:PMC7065822)

Davies, S. P. et al. (2019) Hepatocytes delete regulatory T cells by enclysis, a CD4+ T cell engulfment process. Cell Reports, 29(6), 1610-1620.e4. (doi: 10.1016/j.celrep.2019.09.068) (PMID:31693899) (PMCID:PMC7057271)

Mazzon, M. et al. (2019) Identification of broad-spectrum antiviral compounds by targeting viral entry. Viruses, 11(2), 176. (doi: 10.3390/v11020176) (PMID:30791609) (PMCID:PMC6410080)

Grove, J. , Hu, K., Farquhar, M. J., Goodall, M., Walker, L., Jamshad, M., Drummer, H. E., Bill, R. M., Balfe, P. and McKeating, J. A. (2017) A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81. Wellcome Open Research, 2, 82. (doi: 10.12688/wellcomeopenres.12058.1) (PMID:29090272) (PMCID:PMC5657224)

Lythgoe, K. A., Gardner, A., Pybus, O. G. and Grove, J. (2017) Short-sighted virus evolution and a germline hypothesis for chronic viral infections. Trends in Microbiology, 25(5), pp. 336-348. (doi: 10.1016/j.tim.2017.03.003) (PMID:28377208) (PMCID:PMC5405858)

Culley, S., Towers, G. J., Selwood, D. L., Henriques, R. and Grove, J. (2016) Infection counter: automated quantification of in vitro virus replication by fluorescence microscopy. Viruses, 8(7), 201. (doi: 10.3390/v8070201) (PMID:27455304) (PMCID:PMC4974536)

Grove, J. , Metcalf, D. J., Knight, A. E., Wavre-Shapton, S. T., Sun, T., Protonotarios, E. D., Griffin, L. D., Lippincott-Schwartz, J. and Marsh, M. (2014) Flat clathrin lattices: stable features of the plasma membrane. Molecular Biology of the Cell, 25(22), pp. 3581-3594. (doi: 10.1091/mbc.E14-06-1154) (PMID:25165141) (PMCID:PMC4230618)

Grove, J. (2014) Super-resolution microscopy: a virus' eye view of the cell. Viruses, 6(3), pp. 1365-1378. (doi: 10.3390/v6031365) (PMID:24651030) (PMCID:PMC3970155)

Henry, A. G., Hislop, J. N., Grove, J. , Thorn, K., Marsh, M. and von Zastrow, M. (2012) Regulation of endocytic clathrin dynamics by cargo ubiquitination. Developmental Cell, 23(3), pp. 519-532. (doi: 10.1016/j.devcel.2012.08.003) (PMID:22940114) (PMCID:PMC3470869)

Grove, J. and Marsh, M. (2011) The cell biology of receptor-mediated virus entry. Journal of Cell Biology, 195(7), pp. 1071-1082. (doi: 10.1083/jcb.201108131) (PMID:22123832) (PMCID:PMC3246895)

Brimacombe, C. L. et al. (2011) Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission. Journal of Virology, 85(1), pp. 596-605. (doi: 10.1128/JVI.01592-10) (PMID:20962076) (PMCID:PMC3014195)

Syder, A. J. et al. (2011) Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors. Journal of Hepatology, 54(1), pp. 48-55. (doi: 10.1016/j.jhep.2010.06.024) (PMID:20932595)

Wagoner, J. et al. (2010) Multiple effects of silymarin on the hepatitis C virus lifecycle. Hepatology, 51(6), pp. 1912-1921. (doi: 10.1002/hep.23587) (PMID:20512985) (PMCID:PMC2909978)

Schwarz, A.K., Grove, J. , Hu, K., Mee, C.J., Balfe, P. and McKeating, J.A. (2009) Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. Journal of Virology, 83(23), pp. 12407-12414. (doi: 10.1128/JVI.01552-09) (PMID:19776133) (PMCID:PMC2786758)

Stamataki, Z., Grove, J. , Balfe, P. and McKeating, J.A. (2008) Hepatitis C virus entry and neutralization. Clinics in Liver Disease, 12(3), pp. 693-712. (doi: 10.1016/j.cld.2008.03.008) (PMID:18625435)

Grove, J. , Nielsen, S., Zhong, J., Bassendine, M.F., Drummer, H.E., Balfe, P. and McKeating, J.A. (2008) Identification of a residue in hepatitis C virus E2 glycoprotein that determines scavenger receptor BI and CD81 receptor dependency and sensitivity to neutralizing antibodies. Journal of Virology, 82(24), pp. 12020-12029. (doi: 10.1128/JVI.01569-08) (PMID:18829747) (PMCID:PMC2593310)

Mee, C.J., Grove, J. , Harris, H.J., Hu, K., Balfe, P. and McKeating, J.A. (2008) Effect of cell polarization on hepatitis C virus entry. Journal of Virology, 82(1), pp. 461-470. (doi: 10.1128/JVI.01894-07) (PMID:17959672) (PMCID:PMC2224355)

Reynolds, G.M., Harris, H.J., Jennings, A., Hu, K., Grove, J. , Lalor, P.F., Adams, D.H., Balfe, P., Hübscher, S.G. and McKeating, J.A. (2008) Hepatitis C virus receptor expression in normal and diseased liver tissue. Hepatology, 47(2), pp. 418-427. (doi: 10.1002/hep.22028) (PMID:18085708)

Williams, J.M., Pettitt, T.R., Powell, W., Grove, J. , Savage, C.O.S. and Wakelam, M.J.O. (2007) Antineutrophil cytoplasm antibody-stimulated neutrophil adhesion depends on diacylglycerol kinase-catalyzed phosphatidic acid formation. Journal of the American Society of Nephrology, 18(4), pp. 1112-1120. (doi: 10.1681/ASN.2006090973) (PMID:17360949)

Book Sections

pereira, P. M., Jacobs, C. and Grove, J. (2018) Investigating hepatitis C virus infection using super-resolution microscopy. In: Law, Mansun (ed.) Hepatitis C Virus Protocols. Series: Methods in molecular biology (1911). Humana Press: New York, NY, pp. 247-261. ISBN 9781493989751 (doi: 10.1007/978-1-4939-8976-8_17)

Exhibitions

Skeldon, K. et al. (2023) Research Firsts Exhibition. [Exhibitions]

This list was generated on Fri Mar 28 01:25:34 2025 GMT.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Using machine learning to map protein structure and function in Hepatitis B virus
    Medical Research Foundation
    2024 - 2025
     
  • A human receptor resource for host-pathogen interactions
    Medical Research Council
    2023 - 2026
     
  • Investigating the structural basis of membrane fusion by hepatitis C virus
    University of Edinburgh
    2022 - 2023
     

Professional activities & recognition

Prizes, awards & distinctions

  • 2020: Young Scientist Award (World Economic Forum)

Research fellowships

  • 2016: Wellcome Trust/Royal Society Sir Henry Dale Fellowship

Grant committees & research advisory boards

  • 2022: Wellcome Trust, Early-Career Award

Research datasets

Jump to: 2024
Number of items: 1.

2024

Furnon, W. , Cowton, V. M., De Lorenzo, G. , Orton, R. , Herder, V. , Cantoni, D. , Ilia, G., Correa Mendonca, D. , Kerr, K., Allan, J., Upfold, N. , Meehan, G. R. , Bakshi, S., Das, U. R., Molina Arias, S., McElwee, M., Little, S., Logan, N., Kwok, K. , Smollett, K. , Willett, B. , Da Silva Filipe, A. , Robertson, D. L. , Grove, J. , Patel, A. H. and Palmarini, M. (2024) Phenotypic evolution of SARS-CoV-2 spike throughout the COVID-19 pandemic. [Data Collection]

This list was generated on Fri Mar 28 09:19:15 2025 GMT.

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Dr Joe Grove on Bluesky