Dr Jonathan Coles
- Honorary Research Fellow (School of Infection & Immunity)
email:
Jonathan.Coles@glasgow.ac.uk
Iii - Gbrc, Level 5, Room B5/20, 120 University Place, Glasgow, G12 8TA
Publications
2022
Audshasai, T. et al. (2022) Streptococcus pneumoniae rapidly translocate from the nasopharynx through the cribriform plate to invade the outer meninges. mBio, 13(4), e0102422. (doi: 10.1128/mbio.01024-22) (PMID:35924840) (PMCID:PMC9426477)
Coles, J. (2022) Phototransduction: the decline and fall of the calcium theory. Physiology News(125), pp. 20-23. (doi: 10.36866/pn.25.20)
2017
Coles, J. A., Myburgh, E. , Brewer, J. M. and McMenamin, P. G. (2017) Where are we? The anatomy of the murine cortical meninges revisited for intravital imaging, immunology, and clearance of waste from the brain. Progress in Neurobiology, 156, pp. 107-148. (doi: 10.1016/j.pneurobio.2017.05.002) (PMID:28552391)
Coles, J. A., Stewart-Hutchinson, P. J., Myburgh, E. and Brewer, J. M. (2017) The mouse cortical meninges are the site of immune responses to many different pathogens, and are accessible to intravital imaging. Methods, 127, pp. 53-61. (doi: 10.1016/j.ymeth.2017.03.020) (PMID:28351758) (PMCID:PMC5595162)
2015
Shaw, T. N. et al. (2015) Perivascular arrest of CD8+ T cells is a signature of experimental cerebral malaria. PLoS Pathogens, 11(11), e1005210. (doi: 10.1371/journal.ppat.1005210) (PMID:26562533) (PMCID:PMC4643016)
Coles, J. A., Myburgh, E. , Ritchie, R., Hamilton, A., Rodgers, J. , Mottram, J. C. , Barrett, M. P. and Brewer, J. M. (2015) Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes. PLoS Neglected Tropical Diseases, 9(4), e0003714. (doi: 10.1371/journal.pntd.0003714) (PMID:25881126) (PMCID:PMC4400075)
2013
Myburgh, E. , Coles, J.A., Ritchie, R., Kennedy, P.G.E., McLatchie, A., Rodgers, J. , Taylor, M., Barrett, M. , Brewer, J. and Mottram, J.C. (2013) In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis. PLoS Neglected Tropical Diseases, 7(8), e2384. (doi: 10.1371/journal.pntd.0002384)
2011
Fumagalli, S. et al. (2011) In vivo real-time multiphoton imaging of t lymphocytes in the mouse brain after experimental stroke. Stroke, 42(5), pp. 1429-1436. (doi: 10.1161/STROKEAHA.110.603704)
Grillon, E., Farion, R., Fablet, K., De Waard, M., Tse, C. M., Donowitz, M., Rémy, C. and Coles, J. A. (2011) The spatial organization of proton and lactate transport in a rat brain tumor. PLoS ONE, 6(2), e17416. (doi: 10.1371/journal.pone.0017416) (PMID:21390324) (PMCID:PMC3044751)
2009
Wion, D., Christen, T., Barbier, E. L. and Coles, J. A. (2009) PO2 matters in stem cell culture. Cell Stem Cell, 5(3), pp. 242-243. (doi: 10.1016/j.stem.2009.08.009)
Coles, J. A. (2009) Glial cells: invertebrate. In: Squire, Larry R. (ed.) Encyclopedia of Neuroscience. Elsevier: Amsterdam, pp. 749-759. ISBN 9780080450469 (doi: 10.1016/B978-008045046-9.01011-1)
Ricard, C., Coles, J. A., Serduc, R., van der Sanden, B., Verant, P. and Vial, J.-C. (2009) Two-photon imaging. In: Squire, Larry R. (ed.) Encyclopedia of Neuroscience. Elsevier: Amsterdam, pp. 1221-1229. ISBN 9780080450469 (doi: 10.1016/B978-008045046-9.00863-9)
2008
Coles, J. A., Martiel, J.-L. and Laskowska, K. (2008) A glia-neuron alanine/ammonium shuttle is central to energy metabolism in bee retina. Journal of Physiology, 586(8), pp. 2077-2091. (doi: 10.1113/jphysiol.2007.148734)
Vérant, P., Serduc, R., Sanden, B. v. d., Chantal, R., Ricard, C., Coles, J. A. and Vial, J.-C. (2008) Subtraction method for intravital two-photon microscopy: intraparenchymal imaging and quantification of extravasation in mouse brain cortex. Journal of Biomedical Optics, 13(1), 011002. (doi: 10.1117/1.2870083)
2007
Provent, P., Kickler, N., Barbier, E. L., Bergerot, A., Farion, R., Goury, S., Marcaggi, P., Segebarth, C. and Coles, J. A. (2007) The ammonium-induced increase in rat brain lactate concentration is rapid and reversible and is compatible with trafficking and signaling roles for ammonium. Journal of Cerebral Blood Flow and Metabolism, 27(11), pp. 1830-1840. (doi: 10.1038/sj.jcbfm.9600480)
Nehlig, A. and Coles, J. A. (2007) Cellular pathways of energy metabolism in the brain: is glucose used by neurons or astrocytes? Glia, 55(12), pp. 1238-1250. (doi: 10.1002/glia.20376)
Provent, P. et al. (2007) Serial in vivo spectroscopic nuclear magnetic resonance imaging of lactate and extracellular ph in rat gliomas shows redistribution of protons away from sites of glycolysis. Cancer Research, 67(16), pp. 7638-7645. (doi: 10.1158/0008-5472.CAN-06-3459)
2006
Pfeiffer-Guglielmi, B., Coles, J. A., Francke, M., Reichenbach, A., Fleckenstein, B., Jung, G., Nicaise, G. and Hamprecht, B. (2006) Immunocytochemical analysis of rat vagus nerve by antibodies against glycogen phosphorylase isozymes. Brain Research, 1110(1), pp. 23-29. (doi: 10.1016/j.brainres.2006.06.080)
Vérant, P., Serduc, R., Vial, J.-C., Coles, J., Rémy, C. and van der Sanden, B. (2006) An intravital two photon microscopy method for imaging mouse brain tissues. In: Faupel, M., Smigielski, P., Brandenburg, A. and Fontaine, J. (eds.) Biophotonics for Life Sciences and Medicine. Fontis Media, pp. 223-237.
2004
Marcaggi, P., Jeanne, M. and Coles, J. A. (2004) Neuron-glial trafficking of NH4+ and K+: separate routes of uptake into glial cells of bee retina. European Journal of Neuroscience, 19(4), pp. 966-976. (doi: 10.1111/j.0953-816X.2004.03165.x)
Coles, J. A. and Deitmer, J. W. (2004) Extracellular potassium and pH: homeostasis and signaling. In: Kettenmann, Helmut and Ransom, Bruce R. (eds.) Neuroglia. Oxford University Press, pp. 334-345. ISBN 9780195152227
2003
Vega, C., Martiel, J.-L., Drouhault, D., Burckhart, M.-F. and Coles, J. A. (2003) Uptake of locally applied deoxyglucose, glucose and lactate by axons and Schwann cells of rat vagus nerve. Journal of Physiology, 546(2), pp. 551-564. (doi: 10.1113/jphysiol.2002.029751)
2001
García-Martín, M.-L., Hérigault, G., Rémy, C., Farion, R., Ballesteros, P., Coles, J. A., Cerdán, S. and Ziegler, A. (2001) Mapping extracellular pH in rat brain gliomas in vivo by H magnetic resonance spectroscopic imaging: comparison with maps of metabolites. Cancer Research, 61(17), pp. 6524-6531.
Marcaggi, P. and Coles, J. A. (2001) Ammonium in nervous tissue: transport across cell membranes, fluxes from neurons to glial cells, and role in signalling. Progress in Neurobiology, 64(2), pp. 157-183. (doi: 10.1016/S0301-0082(00)00043-5)
2000
Marcaggi, P. and Coles, J. A. (2000) A Cl- cotransporter selective for NH4+ over K+ in glial cells of bee retina. Journal of General Physiology, 116(2), pp. 125-142. (doi: 10.1085/jgp.116.2.125)
Beaudu-Lange, C., Colomar, A., Israel, J.-M., Coles, J. A. and Amédée, T. (2000) Spontaneous neuronal activity in organotypic cultures of mouse dorsal root ganglion leads to upregulation of calcium channel expression on remote Schwann cells. Glia, 29(3), pp. 281-287.
Coles, J. A., Véga, C. and Marcaggi, P. (2000) Metabolic trafficking between cells in nervous tissue. In: Agnati, L. F., Fuxe, K., Nicholson, C. and Sykova, E. (eds.) Volume Transmission Revisited. Series: Progress in brain research, 125 (125). Elsevier, pp. 241-254. ISBN 9780444503145 (doi: 10.1016/S0079-6123(00)25014-0)
1999
Coles, J. A., Marcaggi, P. and Lavie, J.-L. (1999) A rapid wavelength changer based on liquid crystal shutters for use in ratiometric microspectrophotometry. Pflügers Archiv - European Journal of Physiology, 437(6), pp. 986-989. (doi: 10.1007/s004240050871)
1998
Véga, C., Poitry-Yamate, C. L., Jirounek, P., Tsacopoulos, M. and Coles, J. A. (1998) Lactate is released and taken up by isolated rabbit vagus nerve during aerobic metabolism. Journal of Neurochemistry, 71(1), pp. 330-337. (doi: 10.1046/j.1471-4159.1998.71010330.x)
Beaudu-Lange, C., Despeyroux, S., Marcaggi, P., Coles, J. A. and Amédée, T. (1998) Functional Ca2+ and Na+ channels on mouse Schwann cells cultured in serum-free medium: regulation by a diffusible factor from neurons and by cAMP. European Journal of Neuroscience, 10(5), pp. 1796-1809. (doi: 10.1046/j.1460-9568.1998.00193.x)
Robinson, S. R., Schousboe, A., Dringen, R., Magistretti, P., Coles, J. and Hertz, L. (1998) Metabolic trafficking between neurons and glia. In: Laming, Peter R., Sykova, Eva, Reichenbach, Andreas, Hatton, Glenn I. and Bauer, Herbert (eds.) Glial Cells: their Role in Behaviour. Cambridge University Press, pp. 83-106. ISBN 9780521573689
1997
Amédée, T., Robert, A. and Coles, J. A. (1997) Potassium homeostasis and glial energy metabolism. Glia, 21(1), pp. 46-55. (doi: 10.1002/(SICI)1098-1136(199709)21:1<46::AID-GLIA5>3.0.CO;2-#)
Despeyroux, S., Beaudu-Lange, C., Coles, J. A. and Amédée, T. (1997) Selective downregulation of an inactivating K+ conductance by analogues of cAMP in mouse Schwann cells. Journal of Physiology, 499(3), pp. 655-660.
1996
Coles, J. A., Marcaggi, P., Véga, C. and Cotillon, N. (1996) Effects of photoreceptor metabolism on interstitial and glial cell pH in bee retina: evidence of a role for NH4+. Journal of Physiology, 495(2), pp. 305-318.
Coles, J. A. and Abbott, N. J. (1996) Signalling from neurones to glial cells in invertebrates. Trends in Neurosciences, 19(8), pp. 358-362. (doi: 10.1016/0166-2236(96)10042-4)
1995
Taylor, G. C., Coles, J. A. and Eilbeck, J. C. (1995) Conditions under which Na+channels can boost conduction of small graded potentials. Journal of Theoretical Biology, 172(4), pp. 379-386. (doi: 10.1006/jtbi.1995.0035)
Coles, J. A. (1995) Glial cells and the supply of substrates of energy metabolism to neurons. In: Kettenmann, Helmut and Ransom, Bruce R. (eds.) Neuroglia. Oxford University Press, pp. 793-804. ISBN 9780195078473
Coles, J. A. (1995) Measurement of cytosolic chloride activityby ion-selective microelectrodes. In: Kraicer, Jacob and Dixon, Samuel Jeffrey (eds.) Measurement and Manipulation of Intracellular Ions. Series: Methods in Neurosciences (27). Academic Press, pp. 340-360. ISBN 9780121852979 (doi: 10.1016/S1043-9471(06)80021-2)
Taylor, G. C., Coles, J. A. and Eilbeck, J. C. (1995) Mathematical modelling of weakly nonlinear pulses in a retinal neuron. Chaos, Solitons and Fractals, 5(3-4), pp. 407-413. (doi: 10.1016/0960-0779(93)E0032-7)
1994
Despeyroux, S., Amédée, T. and Coles, J. A. (1994) Axon contact is associated with modified expression of functional potassium channels in mouse Schwann cells. Proceedings of the Royal Society of London Series B: Biological Sciences, 258(1353), pp. 255-260. (doi: 10.1098/rspb.1994.0170)
Cardinaud, B., Coles, J. A., Perrottet, P., Spencer, A. J., Osborne, M. P. and Tsacopoulos, M. (1994) The composition of the interstitial fluid in the retina of the honeybee drone: implications for the supply of substrates of energy metabolism from blood to neurons. Proceedings of the Royal Society of London Series B: Biological Sciences, 257(1348), pp. 49-58. (doi: 10.1098/rspb.1994.0093)
1993
Vallet, A.M. and Coles, J. A. (1993) Is the membrane voltage amplifier of drone photoreceptors useful at physiological light intensities? Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 173(2), pp. 163-168. (doi: 10.1007/BF00192975)
Vallet, A.M. and Coles, J.A. (1993) The perception of small objects by the drone honeybee. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 172(2), pp. 183-188.
1992
Vallet, A. M., Coles, J. A., Eilbeck, J. C. and Scott, A. C. (1992) Membrane conductances involved in amplification of small signals by sodium channels in photoreceptors of drone honey bee. Journal of Physiology, 456(1), pp. 303-324.
Coles, J. A. (1992) Calibration of ion-selective microelectrodes. In: Kettenmann, Helmut and Grantyn, Rosemarie (eds.) Practical Electrophysiological Methods: A Guide for In Vitro Studies in Vertebrate Neurobiology. Wiley-Liss, pp. 228-234. ISBN 9780471562009
1991
Coles, J. A. and Poulain, D. A. (1991) Extracellular K+ in the supraoptic nucleus of the rat during reflex bursting activity by oxytocin neurones. Journal of Physiology, 439(1), pp. 383-409.
Thomas, R. C., Coles, J. A. and Deitmer, J. W. (1991) Homeostatic muffling. Nature, 350(6319), p. 564. (doi: 10.1038/350564b0)
Coles, J. A. and Vallet, A. M. (1991) Signal-to-noise ratio at high light intensities in drone photoreceptors. Neuroscience Research, Suppl(15), S1-S11.
Vallet, A. M. and Coles, J. A. (1991) A method for estimating the minimum visual stimulus that evokes a behavioural response in the drone, apis mellifera ♂. Vision Research, 31(7-8), pp. 1453-1455. (doi: 10.1016/0042-6989(91)90065-D)
1989
Marrero, H., Astion, M. L., Coles, J. A. and Orkand, R. K. (1989) Facilitation of voltage-gated ion channels in frog neuroglia by nerve impulses. Nature, 339(6223), pp. 378-380. (doi: 10.1038/339378a0)
Karwoski, C. J., Coles, J. A., Lu, H.-K. and Huang, B. (1989) Current-evoked transcellular K+ flux in frog retina. Journal of Neurophysiology, 61(5), pp. 939-952.
Coles, J. A. and Schneider-Picard, G. (1989) Amplification of small signals by voltage-gated sodium channels in drone photoreceptors. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 165(1), pp. 109-118. (doi: 10.1007/BF00613804)
Coles, J. A., Giovannini, P. and Schneider-Picard, G. (1989) Effects of light stimulation on pH in photoreceptors, glial cells and extracellular space in drone retina. Acta physiologica Scandinavica. Supplementum, 582, p. 60.
Coles, J. (1989) Functions of glial cells in the retina of the honeybee drone. Glia, 2(1), pp. 1-9. (doi: 10.1002/glia.440020102)
Coles, J. A., Orkand, R. K. and Yamate, C. L. (1989) Chloride enters glial cells and photoreceptors in response to light stimulation in the retina of the honey bee drone. Glia, 2(5), pp. 287-297. (doi: 10.1002/glia.440020502)
Coles, J. A. and Schneider-Picard, G. (1989) Increase in glial intracellular K+ in drone retina caused by photostimulation but not mediated by an increase in extracellular K+. Glia, 2(4), pp. 213-222. (doi: 10.1002/glia.440020402)
1988
Coles, J. A. (1988) Bias current modifies the selectivity of liquid membrane ion-selective microelectrodes. Pflügers Archiv - European Journal of Physiology, 411(3), pp. 339-344. (doi: 10.1007/BF00585125)
Astion, M. L., Coles, J. A., Orkand, R. K. and Abbott, N. J. (1988) K+ accumulation in the space between giant axon and Schwann cell in the squid Alloteuthis: effects of changes in osmolarity. Biophysical Journal, 53(2), pp. 281-285. (doi: 10.1016/S0006-3495(88)83090-X)
1987
Munoz, J.-L. and Coles, J. A. (1987) Quartz micropipettes for intracellular voltage microelectrodes and ion-selective microelectrodes. Journal of Neuroscience Methods, 22(1), pp. 57-64. (doi: 10.1016/0165-0270(87)90090-2)
Astion, M. L., Coles, J. A. and Orkand, R. K. (1987) Effects of bicarbonate on glial cell membrane potential in Necturus optic nerve. Neuroscience Letters, 76(1), pp. 47-52. (doi: 10.1016/0304-3940(87)90190-X)
Tsacopoulos, M., Coles, J. A. and Van de Werve, G. (1987) The supply of metabolic substrate from glia to photoreceptors in the retina of the honeybee drone. Journal de physiologie, 82(4), pp. 279-287.
1986
Coles, J. A., Orkand, R. K., Yamate, C. L. and Tsacopoulos, M. (1986) Free concentrations of Na, K, and Cl in the retina of the honeybee drone: stimulus-induced redistribution and homeostasis. Annals of the New York Academy of Sciences, 481, pp. 303-317. (doi: 10.1111/j.1749-6632.1986.tb27160.x)
Coles, J. A. (1986) Homeostasis of extracellular fluid in retinas of invertebrates and vertebrates. In: Autrum, Hansjochem, Ottoson, David, Perl, Edward R., Schmidt, Robert S., Shimazu, Hiroshi and Willis, William D. (eds.) Progress in Sensory Physiology. Springer, pp. 105-138. ISBN 9783642704130 (doi: 10.1007/978-3-642-70411-6_3)
1985
Schneider-Picard, G., Coles, J. A. and Girardier, L. (1985) Alpha- and beta-adrenergic mediation of changes in metabolism and Na/K exchange in rat brown fat. Journal of General Physiology, 86(2), pp. 169-188. (doi: 10.1085/jgp.86.2.169)
Coles, J. A. and Orkand, R. K. (1985) Changes in sodium activity during light stimulation in photoreceptors, glia and extracellular space in drone retina. Journal of Physiology, 362(1), pp. 415-435.
Coles, J.A. and Rick, R. (1985) An electron microprobe analysis of photoreceptors and outer pigment cells in the retina of the honeybee drone. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 156(2), pp. 213-222. (doi: 10.1007/BF00610864)
1984
Orkand, R.K., Dietzel, I. and Coles, J.A. (1984) Light-induced changes in extracellular volume in the retina of the drone, Apis mellifera. Neuroscience Letters, 45(3), pp. 273-278. (doi: 10.1016/0304-3940(84)90238-6)
1983
Coles, J. A. and Orkand, R. K. (1983) Modification of potassium movement through the retina of the drone (Apis mellifera male) by glial uptake. Journal of Physiology, 340(1), pp. 157-174.
Munoz, J.-L., Deyhimi, F. and Coles, J.A. (1983) Silanization of glass in the making of ion-sensitive microelectrodes. Journal of Neuroscience Methods, 8(3), pp. 231-247. (doi: 10.1016/0165-0270(83)90037-7)
Tsacopoulos, M., Orkand, R. K., Coles, J. A., Levy, S. and Poitry, S. (1983) Oxygen uptake occurs faster than sodium pumping in bee retina after a light flash. Nature, 301(5901), pp. 604-606. (doi: 10.1038/301604a0)
1982
Deyhimi, F. and Coles, J. A. (1982) Rapid silylation of a glass surface: choice of reagent and effect of experimental parameters on hydrophobicity. Helvetica Chimica Acta, 65(6), pp. 1752-1759. (doi: 10.1002/hlca.19820650610)
1981
Coles, J. A. and Tsacopoulos, M. (1981) Ionic and possible metabolic interactions between sensory neurones and glial cells in the retina of the honeybee drone. Journal of Experimental Biology, 95, pp. 75-92.
Gardner-Medwin, A. R., Coles, J. A. and Tsacopoulos, M. (1981) Clearance of extracellular potassium: evidence for spatial buffering by glial cells in the retina of the drone. Brain Research, 209(2), pp. 452-457. (doi: 10.1016/0006-8993(81)90169-4)
Coles, J. A., Tsacopoulos, M., Rabineau, P. and Gardner-Medwin, A. R. (1981) Movement of potassium into glial cells in the retina of the drone, Apis mellifera, during photostimulation. In: Syková, Eva, Hnik, Pavel and Vyklický, Ladislav (eds.) Ion-Selective Microelectrodes and Their Use in Excitable Tissues. Springer, pp. 345-349. ISBN 9781461592266 (doi: 10.1007/978-1-4615-9224-2_41)
1979
Brown, J. E. and Coles, J. A. (1979) Saturation of the response to light in Limulus ventral photoreceptor. Journal of Physiology, 296(1), pp. 373-392.
Coles, J. A. and Tsacopoulos, M. (1979) Potassium activity in photoreceptors, glial cells and extracellular space in the drone retina: changes during photostimulation. Journal of Physiology, 290(2), pp. 525-549.
1977
Brown, J. E., Coles, J. A. and Pinto, L. H. (1977) Effects of injections of calcium and EGTA into the outer segments of retinal rods of Bufo marinus. Journal of Physiology, 269(3), pp. 707-722.
Levy, S. and Coles, J. A. (1977) Intracellular pH of Limulus ventral photoreceptor measured with a double-barrelled pH microelectrode. Experientia, 33(4), pp. 553-554. (doi: 10.1007/BF01922268)
1976
Coles, J. A. and Brown, J. E. (1976) Effects of increased intracellular pH-buffering capacity on the light response of Limulus ventral photoreceptor. Biochimica et Biophysica Acta: Biomembranes, 436(1), pp. 140-153. (doi: 10.1016/0005-2736(76)90226-1)
1975
Toyoda, J.-I. and Coles, J. A. (1975) Rod response to sinusoidally flickering light. Vision Research, 15(8-9), pp. 981-983. (doi: 10.1016/0042-6989(75)90240-0)
Coles, J. A. and Yamane, S. (1975) Effects of adapting lights on the time course of the receptor potential of the anuran retinal rod. Journal of Physiology, 247(1), pp. 189-207.
1972
Coles, J. A. (1972) Light-induced changes in the electrical impedance of the isolated frog retina. Journal of Physiology, 227(3), pp. 815-838.
1971
Coles, J. A. (1971) Some reflective properties of the tapetum lucidum of the cat's eye. Journal of Physiology, 212(2), pp. 393-409.
Articles
Audshasai, T. et al. (2022) Streptococcus pneumoniae rapidly translocate from the nasopharynx through the cribriform plate to invade the outer meninges. mBio, 13(4), e0102422. (doi: 10.1128/mbio.01024-22) (PMID:35924840) (PMCID:PMC9426477)
Coles, J. (2022) Phototransduction: the decline and fall of the calcium theory. Physiology News(125), pp. 20-23. (doi: 10.36866/pn.25.20)
Coles, J. A., Myburgh, E. , Brewer, J. M. and McMenamin, P. G. (2017) Where are we? The anatomy of the murine cortical meninges revisited for intravital imaging, immunology, and clearance of waste from the brain. Progress in Neurobiology, 156, pp. 107-148. (doi: 10.1016/j.pneurobio.2017.05.002) (PMID:28552391)
Coles, J. A., Stewart-Hutchinson, P. J., Myburgh, E. and Brewer, J. M. (2017) The mouse cortical meninges are the site of immune responses to many different pathogens, and are accessible to intravital imaging. Methods, 127, pp. 53-61. (doi: 10.1016/j.ymeth.2017.03.020) (PMID:28351758) (PMCID:PMC5595162)
Shaw, T. N. et al. (2015) Perivascular arrest of CD8+ T cells is a signature of experimental cerebral malaria. PLoS Pathogens, 11(11), e1005210. (doi: 10.1371/journal.ppat.1005210) (PMID:26562533) (PMCID:PMC4643016)
Coles, J. A., Myburgh, E. , Ritchie, R., Hamilton, A., Rodgers, J. , Mottram, J. C. , Barrett, M. P. and Brewer, J. M. (2015) Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes. PLoS Neglected Tropical Diseases, 9(4), e0003714. (doi: 10.1371/journal.pntd.0003714) (PMID:25881126) (PMCID:PMC4400075)
Myburgh, E. , Coles, J.A., Ritchie, R., Kennedy, P.G.E., McLatchie, A., Rodgers, J. , Taylor, M., Barrett, M. , Brewer, J. and Mottram, J.C. (2013) In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis. PLoS Neglected Tropical Diseases, 7(8), e2384. (doi: 10.1371/journal.pntd.0002384)
Fumagalli, S. et al. (2011) In vivo real-time multiphoton imaging of t lymphocytes in the mouse brain after experimental stroke. Stroke, 42(5), pp. 1429-1436. (doi: 10.1161/STROKEAHA.110.603704)
Grillon, E., Farion, R., Fablet, K., De Waard, M., Tse, C. M., Donowitz, M., Rémy, C. and Coles, J. A. (2011) The spatial organization of proton and lactate transport in a rat brain tumor. PLoS ONE, 6(2), e17416. (doi: 10.1371/journal.pone.0017416) (PMID:21390324) (PMCID:PMC3044751)
Wion, D., Christen, T., Barbier, E. L. and Coles, J. A. (2009) PO2 matters in stem cell culture. Cell Stem Cell, 5(3), pp. 242-243. (doi: 10.1016/j.stem.2009.08.009)
Coles, J. A., Martiel, J.-L. and Laskowska, K. (2008) A glia-neuron alanine/ammonium shuttle is central to energy metabolism in bee retina. Journal of Physiology, 586(8), pp. 2077-2091. (doi: 10.1113/jphysiol.2007.148734)
Vérant, P., Serduc, R., Sanden, B. v. d., Chantal, R., Ricard, C., Coles, J. A. and Vial, J.-C. (2008) Subtraction method for intravital two-photon microscopy: intraparenchymal imaging and quantification of extravasation in mouse brain cortex. Journal of Biomedical Optics, 13(1), 011002. (doi: 10.1117/1.2870083)
Provent, P., Kickler, N., Barbier, E. L., Bergerot, A., Farion, R., Goury, S., Marcaggi, P., Segebarth, C. and Coles, J. A. (2007) The ammonium-induced increase in rat brain lactate concentration is rapid and reversible and is compatible with trafficking and signaling roles for ammonium. Journal of Cerebral Blood Flow and Metabolism, 27(11), pp. 1830-1840. (doi: 10.1038/sj.jcbfm.9600480)
Nehlig, A. and Coles, J. A. (2007) Cellular pathways of energy metabolism in the brain: is glucose used by neurons or astrocytes? Glia, 55(12), pp. 1238-1250. (doi: 10.1002/glia.20376)
Provent, P. et al. (2007) Serial in vivo spectroscopic nuclear magnetic resonance imaging of lactate and extracellular ph in rat gliomas shows redistribution of protons away from sites of glycolysis. Cancer Research, 67(16), pp. 7638-7645. (doi: 10.1158/0008-5472.CAN-06-3459)
Pfeiffer-Guglielmi, B., Coles, J. A., Francke, M., Reichenbach, A., Fleckenstein, B., Jung, G., Nicaise, G. and Hamprecht, B. (2006) Immunocytochemical analysis of rat vagus nerve by antibodies against glycogen phosphorylase isozymes. Brain Research, 1110(1), pp. 23-29. (doi: 10.1016/j.brainres.2006.06.080)
Marcaggi, P., Jeanne, M. and Coles, J. A. (2004) Neuron-glial trafficking of NH4+ and K+: separate routes of uptake into glial cells of bee retina. European Journal of Neuroscience, 19(4), pp. 966-976. (doi: 10.1111/j.0953-816X.2004.03165.x)
Vega, C., Martiel, J.-L., Drouhault, D., Burckhart, M.-F. and Coles, J. A. (2003) Uptake of locally applied deoxyglucose, glucose and lactate by axons and Schwann cells of rat vagus nerve. Journal of Physiology, 546(2), pp. 551-564. (doi: 10.1113/jphysiol.2002.029751)
García-Martín, M.-L., Hérigault, G., Rémy, C., Farion, R., Ballesteros, P., Coles, J. A., Cerdán, S. and Ziegler, A. (2001) Mapping extracellular pH in rat brain gliomas in vivo by H magnetic resonance spectroscopic imaging: comparison with maps of metabolites. Cancer Research, 61(17), pp. 6524-6531.
Marcaggi, P. and Coles, J. A. (2001) Ammonium in nervous tissue: transport across cell membranes, fluxes from neurons to glial cells, and role in signalling. Progress in Neurobiology, 64(2), pp. 157-183. (doi: 10.1016/S0301-0082(00)00043-5)
Marcaggi, P. and Coles, J. A. (2000) A Cl- cotransporter selective for NH4+ over K+ in glial cells of bee retina. Journal of General Physiology, 116(2), pp. 125-142. (doi: 10.1085/jgp.116.2.125)
Beaudu-Lange, C., Colomar, A., Israel, J.-M., Coles, J. A. and Amédée, T. (2000) Spontaneous neuronal activity in organotypic cultures of mouse dorsal root ganglion leads to upregulation of calcium channel expression on remote Schwann cells. Glia, 29(3), pp. 281-287.
Coles, J. A., Marcaggi, P. and Lavie, J.-L. (1999) A rapid wavelength changer based on liquid crystal shutters for use in ratiometric microspectrophotometry. Pflügers Archiv - European Journal of Physiology, 437(6), pp. 986-989. (doi: 10.1007/s004240050871)
Véga, C., Poitry-Yamate, C. L., Jirounek, P., Tsacopoulos, M. and Coles, J. A. (1998) Lactate is released and taken up by isolated rabbit vagus nerve during aerobic metabolism. Journal of Neurochemistry, 71(1), pp. 330-337. (doi: 10.1046/j.1471-4159.1998.71010330.x)
Beaudu-Lange, C., Despeyroux, S., Marcaggi, P., Coles, J. A. and Amédée, T. (1998) Functional Ca2+ and Na+ channels on mouse Schwann cells cultured in serum-free medium: regulation by a diffusible factor from neurons and by cAMP. European Journal of Neuroscience, 10(5), pp. 1796-1809. (doi: 10.1046/j.1460-9568.1998.00193.x)
Amédée, T., Robert, A. and Coles, J. A. (1997) Potassium homeostasis and glial energy metabolism. Glia, 21(1), pp. 46-55. (doi: 10.1002/(SICI)1098-1136(199709)21:1<46::AID-GLIA5>3.0.CO;2-#)
Despeyroux, S., Beaudu-Lange, C., Coles, J. A. and Amédée, T. (1997) Selective downregulation of an inactivating K+ conductance by analogues of cAMP in mouse Schwann cells. Journal of Physiology, 499(3), pp. 655-660.
Coles, J. A., Marcaggi, P., Véga, C. and Cotillon, N. (1996) Effects of photoreceptor metabolism on interstitial and glial cell pH in bee retina: evidence of a role for NH4+. Journal of Physiology, 495(2), pp. 305-318.
Coles, J. A. and Abbott, N. J. (1996) Signalling from neurones to glial cells in invertebrates. Trends in Neurosciences, 19(8), pp. 358-362. (doi: 10.1016/0166-2236(96)10042-4)
Taylor, G. C., Coles, J. A. and Eilbeck, J. C. (1995) Conditions under which Na+channels can boost conduction of small graded potentials. Journal of Theoretical Biology, 172(4), pp. 379-386. (doi: 10.1006/jtbi.1995.0035)
Taylor, G. C., Coles, J. A. and Eilbeck, J. C. (1995) Mathematical modelling of weakly nonlinear pulses in a retinal neuron. Chaos, Solitons and Fractals, 5(3-4), pp. 407-413. (doi: 10.1016/0960-0779(93)E0032-7)
Despeyroux, S., Amédée, T. and Coles, J. A. (1994) Axon contact is associated with modified expression of functional potassium channels in mouse Schwann cells. Proceedings of the Royal Society of London Series B: Biological Sciences, 258(1353), pp. 255-260. (doi: 10.1098/rspb.1994.0170)
Cardinaud, B., Coles, J. A., Perrottet, P., Spencer, A. J., Osborne, M. P. and Tsacopoulos, M. (1994) The composition of the interstitial fluid in the retina of the honeybee drone: implications for the supply of substrates of energy metabolism from blood to neurons. Proceedings of the Royal Society of London Series B: Biological Sciences, 257(1348), pp. 49-58. (doi: 10.1098/rspb.1994.0093)
Vallet, A.M. and Coles, J. A. (1993) Is the membrane voltage amplifier of drone photoreceptors useful at physiological light intensities? Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 173(2), pp. 163-168. (doi: 10.1007/BF00192975)
Vallet, A.M. and Coles, J.A. (1993) The perception of small objects by the drone honeybee. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 172(2), pp. 183-188.
Vallet, A. M., Coles, J. A., Eilbeck, J. C. and Scott, A. C. (1992) Membrane conductances involved in amplification of small signals by sodium channels in photoreceptors of drone honey bee. Journal of Physiology, 456(1), pp. 303-324.
Coles, J. A. and Poulain, D. A. (1991) Extracellular K+ in the supraoptic nucleus of the rat during reflex bursting activity by oxytocin neurones. Journal of Physiology, 439(1), pp. 383-409.
Thomas, R. C., Coles, J. A. and Deitmer, J. W. (1991) Homeostatic muffling. Nature, 350(6319), p. 564. (doi: 10.1038/350564b0)
Coles, J. A. and Vallet, A. M. (1991) Signal-to-noise ratio at high light intensities in drone photoreceptors. Neuroscience Research, Suppl(15), S1-S11.
Vallet, A. M. and Coles, J. A. (1991) A method for estimating the minimum visual stimulus that evokes a behavioural response in the drone, apis mellifera ♂. Vision Research, 31(7-8), pp. 1453-1455. (doi: 10.1016/0042-6989(91)90065-D)
Marrero, H., Astion, M. L., Coles, J. A. and Orkand, R. K. (1989) Facilitation of voltage-gated ion channels in frog neuroglia by nerve impulses. Nature, 339(6223), pp. 378-380. (doi: 10.1038/339378a0)
Karwoski, C. J., Coles, J. A., Lu, H.-K. and Huang, B. (1989) Current-evoked transcellular K+ flux in frog retina. Journal of Neurophysiology, 61(5), pp. 939-952.
Coles, J. A. and Schneider-Picard, G. (1989) Amplification of small signals by voltage-gated sodium channels in drone photoreceptors. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 165(1), pp. 109-118. (doi: 10.1007/BF00613804)
Coles, J. A., Giovannini, P. and Schneider-Picard, G. (1989) Effects of light stimulation on pH in photoreceptors, glial cells and extracellular space in drone retina. Acta physiologica Scandinavica. Supplementum, 582, p. 60.
Coles, J. (1989) Functions of glial cells in the retina of the honeybee drone. Glia, 2(1), pp. 1-9. (doi: 10.1002/glia.440020102)
Coles, J. A., Orkand, R. K. and Yamate, C. L. (1989) Chloride enters glial cells and photoreceptors in response to light stimulation in the retina of the honey bee drone. Glia, 2(5), pp. 287-297. (doi: 10.1002/glia.440020502)
Coles, J. A. and Schneider-Picard, G. (1989) Increase in glial intracellular K+ in drone retina caused by photostimulation but not mediated by an increase in extracellular K+. Glia, 2(4), pp. 213-222. (doi: 10.1002/glia.440020402)
Coles, J. A. (1988) Bias current modifies the selectivity of liquid membrane ion-selective microelectrodes. Pflügers Archiv - European Journal of Physiology, 411(3), pp. 339-344. (doi: 10.1007/BF00585125)
Astion, M. L., Coles, J. A., Orkand, R. K. and Abbott, N. J. (1988) K+ accumulation in the space between giant axon and Schwann cell in the squid Alloteuthis: effects of changes in osmolarity. Biophysical Journal, 53(2), pp. 281-285. (doi: 10.1016/S0006-3495(88)83090-X)
Munoz, J.-L. and Coles, J. A. (1987) Quartz micropipettes for intracellular voltage microelectrodes and ion-selective microelectrodes. Journal of Neuroscience Methods, 22(1), pp. 57-64. (doi: 10.1016/0165-0270(87)90090-2)
Astion, M. L., Coles, J. A. and Orkand, R. K. (1987) Effects of bicarbonate on glial cell membrane potential in Necturus optic nerve. Neuroscience Letters, 76(1), pp. 47-52. (doi: 10.1016/0304-3940(87)90190-X)
Tsacopoulos, M., Coles, J. A. and Van de Werve, G. (1987) The supply of metabolic substrate from glia to photoreceptors in the retina of the honeybee drone. Journal de physiologie, 82(4), pp. 279-287.
Coles, J. A., Orkand, R. K., Yamate, C. L. and Tsacopoulos, M. (1986) Free concentrations of Na, K, and Cl in the retina of the honeybee drone: stimulus-induced redistribution and homeostasis. Annals of the New York Academy of Sciences, 481, pp. 303-317. (doi: 10.1111/j.1749-6632.1986.tb27160.x)
Schneider-Picard, G., Coles, J. A. and Girardier, L. (1985) Alpha- and beta-adrenergic mediation of changes in metabolism and Na/K exchange in rat brown fat. Journal of General Physiology, 86(2), pp. 169-188. (doi: 10.1085/jgp.86.2.169)
Coles, J. A. and Orkand, R. K. (1985) Changes in sodium activity during light stimulation in photoreceptors, glia and extracellular space in drone retina. Journal of Physiology, 362(1), pp. 415-435.
Coles, J.A. and Rick, R. (1985) An electron microprobe analysis of photoreceptors and outer pigment cells in the retina of the honeybee drone. Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 156(2), pp. 213-222. (doi: 10.1007/BF00610864)
Orkand, R.K., Dietzel, I. and Coles, J.A. (1984) Light-induced changes in extracellular volume in the retina of the drone, Apis mellifera. Neuroscience Letters, 45(3), pp. 273-278. (doi: 10.1016/0304-3940(84)90238-6)
Coles, J. A. and Orkand, R. K. (1983) Modification of potassium movement through the retina of the drone (Apis mellifera male) by glial uptake. Journal of Physiology, 340(1), pp. 157-174.
Munoz, J.-L., Deyhimi, F. and Coles, J.A. (1983) Silanization of glass in the making of ion-sensitive microelectrodes. Journal of Neuroscience Methods, 8(3), pp. 231-247. (doi: 10.1016/0165-0270(83)90037-7)
Tsacopoulos, M., Orkand, R. K., Coles, J. A., Levy, S. and Poitry, S. (1983) Oxygen uptake occurs faster than sodium pumping in bee retina after a light flash. Nature, 301(5901), pp. 604-606. (doi: 10.1038/301604a0)
Deyhimi, F. and Coles, J. A. (1982) Rapid silylation of a glass surface: choice of reagent and effect of experimental parameters on hydrophobicity. Helvetica Chimica Acta, 65(6), pp. 1752-1759. (doi: 10.1002/hlca.19820650610)
Coles, J. A. and Tsacopoulos, M. (1981) Ionic and possible metabolic interactions between sensory neurones and glial cells in the retina of the honeybee drone. Journal of Experimental Biology, 95, pp. 75-92.
Gardner-Medwin, A. R., Coles, J. A. and Tsacopoulos, M. (1981) Clearance of extracellular potassium: evidence for spatial buffering by glial cells in the retina of the drone. Brain Research, 209(2), pp. 452-457. (doi: 10.1016/0006-8993(81)90169-4)
Brown, J. E. and Coles, J. A. (1979) Saturation of the response to light in Limulus ventral photoreceptor. Journal of Physiology, 296(1), pp. 373-392.
Coles, J. A. and Tsacopoulos, M. (1979) Potassium activity in photoreceptors, glial cells and extracellular space in the drone retina: changes during photostimulation. Journal of Physiology, 290(2), pp. 525-549.
Brown, J. E., Coles, J. A. and Pinto, L. H. (1977) Effects of injections of calcium and EGTA into the outer segments of retinal rods of Bufo marinus. Journal of Physiology, 269(3), pp. 707-722.
Levy, S. and Coles, J. A. (1977) Intracellular pH of Limulus ventral photoreceptor measured with a double-barrelled pH microelectrode. Experientia, 33(4), pp. 553-554. (doi: 10.1007/BF01922268)
Coles, J. A. and Brown, J. E. (1976) Effects of increased intracellular pH-buffering capacity on the light response of Limulus ventral photoreceptor. Biochimica et Biophysica Acta: Biomembranes, 436(1), pp. 140-153. (doi: 10.1016/0005-2736(76)90226-1)
Toyoda, J.-I. and Coles, J. A. (1975) Rod response to sinusoidally flickering light. Vision Research, 15(8-9), pp. 981-983. (doi: 10.1016/0042-6989(75)90240-0)
Coles, J. A. and Yamane, S. (1975) Effects of adapting lights on the time course of the receptor potential of the anuran retinal rod. Journal of Physiology, 247(1), pp. 189-207.
Coles, J. A. (1972) Light-induced changes in the electrical impedance of the isolated frog retina. Journal of Physiology, 227(3), pp. 815-838.
Coles, J. A. (1971) Some reflective properties of the tapetum lucidum of the cat's eye. Journal of Physiology, 212(2), pp. 393-409.
Book Sections
Coles, J. A. (2009) Glial cells: invertebrate. In: Squire, Larry R. (ed.) Encyclopedia of Neuroscience. Elsevier: Amsterdam, pp. 749-759. ISBN 9780080450469 (doi: 10.1016/B978-008045046-9.01011-1)
Ricard, C., Coles, J. A., Serduc, R., van der Sanden, B., Verant, P. and Vial, J.-C. (2009) Two-photon imaging. In: Squire, Larry R. (ed.) Encyclopedia of Neuroscience. Elsevier: Amsterdam, pp. 1221-1229. ISBN 9780080450469 (doi: 10.1016/B978-008045046-9.00863-9)
Vérant, P., Serduc, R., Vial, J.-C., Coles, J., Rémy, C. and van der Sanden, B. (2006) An intravital two photon microscopy method for imaging mouse brain tissues. In: Faupel, M., Smigielski, P., Brandenburg, A. and Fontaine, J. (eds.) Biophotonics for Life Sciences and Medicine. Fontis Media, pp. 223-237.
Coles, J. A. and Deitmer, J. W. (2004) Extracellular potassium and pH: homeostasis and signaling. In: Kettenmann, Helmut and Ransom, Bruce R. (eds.) Neuroglia. Oxford University Press, pp. 334-345. ISBN 9780195152227
Coles, J. A., Véga, C. and Marcaggi, P. (2000) Metabolic trafficking between cells in nervous tissue. In: Agnati, L. F., Fuxe, K., Nicholson, C. and Sykova, E. (eds.) Volume Transmission Revisited. Series: Progress in brain research, 125 (125). Elsevier, pp. 241-254. ISBN 9780444503145 (doi: 10.1016/S0079-6123(00)25014-0)
Robinson, S. R., Schousboe, A., Dringen, R., Magistretti, P., Coles, J. and Hertz, L. (1998) Metabolic trafficking between neurons and glia. In: Laming, Peter R., Sykova, Eva, Reichenbach, Andreas, Hatton, Glenn I. and Bauer, Herbert (eds.) Glial Cells: their Role in Behaviour. Cambridge University Press, pp. 83-106. ISBN 9780521573689
Coles, J. A. (1995) Glial cells and the supply of substrates of energy metabolism to neurons. In: Kettenmann, Helmut and Ransom, Bruce R. (eds.) Neuroglia. Oxford University Press, pp. 793-804. ISBN 9780195078473
Coles, J. A. (1995) Measurement of cytosolic chloride activityby ion-selective microelectrodes. In: Kraicer, Jacob and Dixon, Samuel Jeffrey (eds.) Measurement and Manipulation of Intracellular Ions. Series: Methods in Neurosciences (27). Academic Press, pp. 340-360. ISBN 9780121852979 (doi: 10.1016/S1043-9471(06)80021-2)
Coles, J. A. (1992) Calibration of ion-selective microelectrodes. In: Kettenmann, Helmut and Grantyn, Rosemarie (eds.) Practical Electrophysiological Methods: A Guide for In Vitro Studies in Vertebrate Neurobiology. Wiley-Liss, pp. 228-234. ISBN 9780471562009
Coles, J. A. (1986) Homeostasis of extracellular fluid in retinas of invertebrates and vertebrates. In: Autrum, Hansjochem, Ottoson, David, Perl, Edward R., Schmidt, Robert S., Shimazu, Hiroshi and Willis, William D. (eds.) Progress in Sensory Physiology. Springer, pp. 105-138. ISBN 9783642704130 (doi: 10.1007/978-3-642-70411-6_3)
Coles, J. A., Tsacopoulos, M., Rabineau, P. and Gardner-Medwin, A. R. (1981) Movement of potassium into glial cells in the retina of the drone, Apis mellifera, during photostimulation. In: Syková, Eva, Hnik, Pavel and Vyklický, Ladislav (eds.) Ion-Selective Microelectrodes and Their Use in Excitable Tissues. Springer, pp. 345-349. ISBN 9781461592266 (doi: 10.1007/978-1-4615-9224-2_41)