Dr John Campbell
- Honorary Professor (School of Infection & Immunity)
email:
John.D.Campbell@glasgow.ac.uk
Snbts, National Science Laboratory, 21 Ellen's Glen Road, Edinburgh EH17 7QT
Publications
2024
Hayes, A. J. et al. (2024) Enhanced CCR2 expression by ACKR2-deficient NK cells enhances increases tumoricidal cell therapy efficacy. Journal of Leukocyte Biology, (doi: 10.1093/jleuko/qiae162) (PMID:39052923) (Early Online Publication)
Cooper, R. S. et al. (2024) EBV T-cell immunotherapy generated by peptide selection has enhanced effector functionality compared to LCL stimulation. Frontiers in Immunology, 15, 1412211. (doi: 10.3389/fimmu.2024.1412211) (PMID:39011042) (PMCID:PMC11246990)
Kelly, C. J., Lindsay, S. L. , Smith, R. S., Keh, S., Cunningham, K. T. , Thümmler, K. , Maizels, R. M. , Campbell, J. D.M. and Barnett, S. C. (2024) Development of good manufacturing practice-compatible isolation and culture methods for human olfactory mucosa-derived mesenchymal stromal cells. International Journal of Molecular Sciences, 25(2), 743. (doi: 10.3390/ijms25020743) (PMID:38255817)
2023
Cuesta-Gomez, N., Medina-Ruiz, L., Graham, G. J. and Campbell, J. D.M. (2023) IL-6 and TGF-β-secreting adoptively-transferred murine mesenchymal stromal cells accelerate healing of psoriasis-like skin inflammation and upregulate IL-17A and TGF-β. International Journal of Molecular Sciences, 24(12), 10132. (doi: 10.3390/ijms241210132) (PMID:37373278) (PMCID:PMC10298958)
2022
Burgoyne, P., Hayes, A. J., Cooper, R. S., Le Brocq, M. L., Hansell, C. A.H., Campbell, J. D.M. and Graham, G. J. (2022) CCR7+ dendritic cells sorted by binding of CCL19 show enhanced Ag-presenting capacity and antitumor potency. Journal of Leukocyte Biology, 111(6), pp. 1243-1251. (doi: 10.1002/JLB.5AB0720-446RR) (PMID:34780080)
2020
Thirlwell, K. L. et al. (2020) Pancreas-derived mesenchymal stromal cells share immune response-modulating and angiogenic potential with bone marrow mesenchymal stromal cells and can be grown to therapeutic scale under Good Manufacturing Practice conditions. Cytotherapy, 22(12), pp. 762-771. (doi: 10.1016/j.jcyt.2020.07.010) (PMID:32828673)
Forbes, S. et al. (2020) Human umbilical cord perivascular cells improve human pancreatic islet transplant function by increasing vascularization. Science Translational Medicine, 12(526), eaan5907. (doi: 10.1126/scitranslmed.aan5907) (PMID:31941825)
2015
Le Brocq, M., Fraser, A. R., Graham, G. J. and Campbell, J. D.M. (2015) CCL19-sorted mature dendritic cells have enhanced lymph node migratory capacity and function. Journal of Inflammation, 12(S1), P2. (doi: 10.1186/1476-9255-12-S1-P2) (PMCID:PMC4416168)
2014
Le Brocq, M. L., Fraser, A. R., Cotton, G., Woznica, K., McCulloch, C. V., Hewit, K. D., McKimmie, C. S., Nibbs, R. J.B. , Campbell, J. D.M. and Graham, G. J. (2014) Chemokines as novel and versatile reagents for flow cytometry and cell sorting. Journal of Immunology, 192(12), pp. 6120-6130. (doi: 10.4049/jimmunol.1303371) (PMID:24850722)
2012
Marr, L.A., Gilham, D.E., Campbell, J.D.M. and Fraser, A.R. (2012) Immunology in the clinic review series; focus on cancer: double trouble for tumours: bi-functional and redirected T cells as effective cancer immunotherapies. Clinical and Experimental Immunology, 167(2), pp. 216-225. (doi: 10.1111/j.1365-2249.2011.04517.x)
2008
Harrison, S., Franklin, I. and Campbell, J. (2008) Enumeration of blood dendritic cells in patients with multiple myeloma at presentation and through therapy. Leukemia and Lymphoma, 49(12), pp. 2272-2283.
2006
Fraser, A., Cook, G., Franklin, I., Templeton, J., Campbell, M., Holyoake, T. and Campbell, J. (2006) Immature monocytes from G-CSF-mobilized peripheral blood stem cell collections carry surface-bound IL-10 and have the potential to modulate alloreactivity. Journal of Leukocyte Biology, 80(4), pp. 862-869. (doi: 10.1189/jlb.0605297)
2005
Jordan, W., Eskdale, J., Boniotto, M., Lennon, G., Peat, J., Campbell, J. and Gallagher, G. (2005) Human IL-19 regulates immunity through auto-induction of IL-19 and production of IL-10. European Journal of Immunology, 35, pp. 1576-1582. (doi: 10.1002/eji.200425317)
2004
Gallagher, G., Eskdale, J., Jordan, W., Peat, J., Campbell, J., Boniotto, M., Lennon, G., Dickensheets, H. and Donnelly, R. (2004) Human interleukin-19 and its receptor: a potential role in the induction of Th2 responses. International Immunopharmacology, 4, pp. 615-626. (doi: 10.1016/j.intimp.2004.01.005)
2001
Campbell, J., Cook, G., Robertson, S., Fraser, A., Boyd, K., Gracie, J. and Franklin, I. (2001) Suppression of IL-2-induced T cell proliferation and phosphorylation of STAT3 and STAT5 by tumor-derived TGF beta is reversed by IL-15. Journal of Immunology, 167, pp. 553-561.
Nibbs, R. et al. (2001) The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. American Journal of Pathology, 158, pp. 867-877.
Articles
Hayes, A. J. et al. (2024) Enhanced CCR2 expression by ACKR2-deficient NK cells enhances increases tumoricidal cell therapy efficacy. Journal of Leukocyte Biology, (doi: 10.1093/jleuko/qiae162) (PMID:39052923) (Early Online Publication)
Cooper, R. S. et al. (2024) EBV T-cell immunotherapy generated by peptide selection has enhanced effector functionality compared to LCL stimulation. Frontiers in Immunology, 15, 1412211. (doi: 10.3389/fimmu.2024.1412211) (PMID:39011042) (PMCID:PMC11246990)
Kelly, C. J., Lindsay, S. L. , Smith, R. S., Keh, S., Cunningham, K. T. , Thümmler, K. , Maizels, R. M. , Campbell, J. D.M. and Barnett, S. C. (2024) Development of good manufacturing practice-compatible isolation and culture methods for human olfactory mucosa-derived mesenchymal stromal cells. International Journal of Molecular Sciences, 25(2), 743. (doi: 10.3390/ijms25020743) (PMID:38255817)
Cuesta-Gomez, N., Medina-Ruiz, L., Graham, G. J. and Campbell, J. D.M. (2023) IL-6 and TGF-β-secreting adoptively-transferred murine mesenchymal stromal cells accelerate healing of psoriasis-like skin inflammation and upregulate IL-17A and TGF-β. International Journal of Molecular Sciences, 24(12), 10132. (doi: 10.3390/ijms241210132) (PMID:37373278) (PMCID:PMC10298958)
Burgoyne, P., Hayes, A. J., Cooper, R. S., Le Brocq, M. L., Hansell, C. A.H., Campbell, J. D.M. and Graham, G. J. (2022) CCR7+ dendritic cells sorted by binding of CCL19 show enhanced Ag-presenting capacity and antitumor potency. Journal of Leukocyte Biology, 111(6), pp. 1243-1251. (doi: 10.1002/JLB.5AB0720-446RR) (PMID:34780080)
Thirlwell, K. L. et al. (2020) Pancreas-derived mesenchymal stromal cells share immune response-modulating and angiogenic potential with bone marrow mesenchymal stromal cells and can be grown to therapeutic scale under Good Manufacturing Practice conditions. Cytotherapy, 22(12), pp. 762-771. (doi: 10.1016/j.jcyt.2020.07.010) (PMID:32828673)
Forbes, S. et al. (2020) Human umbilical cord perivascular cells improve human pancreatic islet transplant function by increasing vascularization. Science Translational Medicine, 12(526), eaan5907. (doi: 10.1126/scitranslmed.aan5907) (PMID:31941825)
Le Brocq, M., Fraser, A. R., Graham, G. J. and Campbell, J. D.M. (2015) CCL19-sorted mature dendritic cells have enhanced lymph node migratory capacity and function. Journal of Inflammation, 12(S1), P2. (doi: 10.1186/1476-9255-12-S1-P2) (PMCID:PMC4416168)
Le Brocq, M. L., Fraser, A. R., Cotton, G., Woznica, K., McCulloch, C. V., Hewit, K. D., McKimmie, C. S., Nibbs, R. J.B. , Campbell, J. D.M. and Graham, G. J. (2014) Chemokines as novel and versatile reagents for flow cytometry and cell sorting. Journal of Immunology, 192(12), pp. 6120-6130. (doi: 10.4049/jimmunol.1303371) (PMID:24850722)
Marr, L.A., Gilham, D.E., Campbell, J.D.M. and Fraser, A.R. (2012) Immunology in the clinic review series; focus on cancer: double trouble for tumours: bi-functional and redirected T cells as effective cancer immunotherapies. Clinical and Experimental Immunology, 167(2), pp. 216-225. (doi: 10.1111/j.1365-2249.2011.04517.x)
Harrison, S., Franklin, I. and Campbell, J. (2008) Enumeration of blood dendritic cells in patients with multiple myeloma at presentation and through therapy. Leukemia and Lymphoma, 49(12), pp. 2272-2283.
Fraser, A., Cook, G., Franklin, I., Templeton, J., Campbell, M., Holyoake, T. and Campbell, J. (2006) Immature monocytes from G-CSF-mobilized peripheral blood stem cell collections carry surface-bound IL-10 and have the potential to modulate alloreactivity. Journal of Leukocyte Biology, 80(4), pp. 862-869. (doi: 10.1189/jlb.0605297)
Jordan, W., Eskdale, J., Boniotto, M., Lennon, G., Peat, J., Campbell, J. and Gallagher, G. (2005) Human IL-19 regulates immunity through auto-induction of IL-19 and production of IL-10. European Journal of Immunology, 35, pp. 1576-1582. (doi: 10.1002/eji.200425317)
Gallagher, G., Eskdale, J., Jordan, W., Peat, J., Campbell, J., Boniotto, M., Lennon, G., Dickensheets, H. and Donnelly, R. (2004) Human interleukin-19 and its receptor: a potential role in the induction of Th2 responses. International Immunopharmacology, 4, pp. 615-626. (doi: 10.1016/j.intimp.2004.01.005)
Campbell, J., Cook, G., Robertson, S., Fraser, A., Boyd, K., Gracie, J. and Franklin, I. (2001) Suppression of IL-2-induced T cell proliferation and phosphorylation of STAT3 and STAT5 by tumor-derived TGF beta is reversed by IL-15. Journal of Immunology, 167, pp. 553-561.
Nibbs, R. et al. (2001) The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. American Journal of Pathology, 158, pp. 867-877.