2024

Camargo da Rosa, L. , Scales, H. E. , Benson, R. A. , Brewer, J. M. , McInnes, I. B. and Garside, P. (2024) The effect of abatacept on T cell activation is not long-lived in vivo. Discovery Immunology, 3(1), kyad029. (doi: 10.1093/discim/kyad029)

2022

Audshasai, T. et al. (2022) Streptococcus pneumoniae rapidly translocate from the nasopharynx through the cribriform plate to invade the outer meninges. mBio, 13(4), e0102422. (doi: 10.1128/mbio.01024-22) (PMID:35924840) (PMCID:PMC9426477)

Prendergast, C. T., Benson, R. A. , Scales, H. E. , Bonilha, C. S., Cole, J. J., McInnes, I. , Brewer, J. M. and Garside, P. (2022) Dissecting the molecular control of immune cell accumulation in the inflamed joint. JCI Insight, 7(7), e151281. (doi: 10.1172/jci.insight.151281) (PMID:35192549) (PMCID:PMC9057592)

Camargo da Rosa, L. , Scales, H. E. , Makhija, S., Sutherland, K., Benson, R. A. , Brewer, J. M. and Garside, P. (2022) Revealing stromal and lymphoid sources of Col3a1-expression during inflammation using a novel reporter mouse. Discovery Immunology, 1(1), kyac008. (doi: 10.1093/discim/kyac008)

Meehan, G. R. , Scales, H. E. , McInnes, I. B. , Brewer, J. M. and Garside, P. (2022) Orally administered antigen can reduce or exacerbate pathology in an animal model of inflammatory arthritis dependent upon the timing of administration. Immunotherapy Advances, 2(1), ltac020. (doi: 10.1093/immadv/ltac020) (PMID:36268500) (PMCID:PMC9579813)

2021

Bonilha, C. S., Benson, R. A. , Scales, H. E. , Brewer, J. M. and Garside, P. (2021) Junctional adhesion molecule-A on dendritic cells regulates Th1 differentiation. Immunology Letters, 235, pp. 32-40. (doi: 10.1016/j.imlet.2021.05.001) (PMID:34000305)

De Lorenzo, G. et al. (2021) Zika virus-like particles bearing covalent dimer of envelope protein protect mice from lethal challenge. Journal of Virology, 95(1), e01415-20. (doi: 10.1128/JVI.01415-20) (PMID:33028720) (PMCID:PMCID: PMC7737734)

2020

Meehan, G. R. , Scales, H. E. , Osii, R., De Niz, M., Lawton, J. C., Marti, M. , Garside, P. , Craig, A. and Brewer, J. M. (2020) Developing a xenograft model of human vasculature in the mouse ear pinna. Scientific Reports, 10, 2058. (doi: 10.1038/s41598-020-58650-y) (PMID:32029768) (PMCID:PMC7004987)

2019

Hayes, A. J. et al. (2019) Spatiotemporal modeling of the key migratory events during the initiation of adaptive immunity. Frontiers in Immunology, 10, 598. (doi: 10.3389/fimmu.2019.00598) (PMID:31024523) (PMCID:PMC6460458)

2018

Scales, H. E. et al. (2018) A novel cellular pathway of antigen presentation and CD4 T cell activation in vivo. Frontiers in Immunology, 9, 2684. (doi: 10.3389/fimmu.2018.02684)

Noonan, J. et al. (2018) In vivo multiplex molecular imaging of vascular inflammation using surface-enhanced Raman spectroscopy. Theranostics, 8(22), pp. 6195-6209. (doi: 10.7150/thno.28665) (PMID:30613292) (PMCID:PMC6299693)

2017

Stephen, J., Scales, H.E. , Benson, R.A. , Erben, D., Garside, P. and Brewer, J.M. (2017) Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity. npj Vaccines, 2, 1. (doi: 10.1038/s41541-016-0001-5) (PMID:29263862) (PMCID:PMC5604741)

2016

Scales, H. E. , Ierna, M., Smith, K. M., Ross, K., Meiklejohn, G. R., Patterson-Kane, J. C., McInnes, I. B., Brewer, J. M. , Garside, P. and Maffia, P. (2016) Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging. Rheumatology, 55(3), pp. 564-572. (doi: 10.1093/rheumatology/kev361) (PMID:26475798)

2010

Ierna, M., Kerr, A., Scales, H. , Berge, K. and Griinari, M. (2010) Supplementation of diet with krill oil protects against experimental rheumatoid arthritis. BMC Musculoskeletal Disorders, 11(1), 136. (doi: 10.1186/1471-2474-11-136) (PMID:20587038) (PMCID:PMC2907316)

2009

Ierna, M.X., Scales, H.E. , Mueller, C. and Lawrence, C.E. (2009) Transmembrane tumor necrosis factor alpha is required for enteropathy and is sufficient to promote parasite expulsion in gastrointestinal helminth infection. Infection and Immunity, 77(9), pp. 3879-3885. (doi: 10.1128/IAI.01461-08) (PMID:19564380) (PMCID:PMC2737992)

2008

Michels, C. E., Scales, H. E. , Saunders, K. A., McGowan, S., Brombracher, F., Alexander, J. and Lawrence, C. E. (2008) Neither interleukin-4 receptor α expression on CD4+ T cells, or macrophages and neutrophils is required for protective immunity to Trichinella spiralis. Immunology, 128(1pt2), e385-e394. (doi: 10.1111/j.1365-2567.2008.02987.x) (PMID:19191917)

Ierna, M.X., Scales, H.E. , Saunders, K.L. and Lawrence, C.E. (2008) Mast cell production of IL-4 and TNF may be required for protective and pathological responses in gastrointestinal helminth infection. Mucosal Immunology, 1, pp. 147-155. (doi: 10.1038/mi.2007.16) (PMID:19079172)

2007

Scales, H.E. , Ierna, M.X. and Lawrence, C.E. (2007) The role of IL-4, IL-13 and IL-4Rα in the development of protective and pathological responses to Trichinella spiralis. Parasite Immunology, 29(2), pp. 81-91. (doi: 10.1111/j.1365-3024.2006.00920.x) (PMID:17241396)

2006

Mann, J. F.S., Scales, H. E. , Shakir, E., Alexander, J., Carter, K. C., Mullen, A. B. and Ferro, V. A. (2006) Oral delivery of tetanus toxoid using vesicles containing bile salts (bilosomes) induces significant systemic and mucosal immunity. Methods, 38(2), 90 - 95. (doi: 10.1016/j.ymeth.2005.11.002) (PMID:16414269)

Ierna, M. X., Scales, H. E. , Schwarz, H., Bunce, C., McIlgorm, A., Garside, P. and Lawrence, C. E. (2006) OX40 interactions in gastrointestinal nematode infection. Immunology, 117(1), pp. 108-116. (doi: 10.1111/j.1365-2567.2005.02271.x) (PMID:16423046)

2005

Boitelle, A., Di Lorenzo, C., Scales, H.E. , Devaney, E. , Kennedy, M.W., Garside, P. and Lawrence, C.E. (2005) Contrasting effects of acute and chronic gastro-intestinal helminth infections on a heterologous immune response in a transgenic adoptive transfer model. International Journal for Parasitology, 35(7), pp. 765-775. (doi: 10.1016/j.ijpara.2005.02.013) (PMID:15893319)

2004

Scales, H. E. , Ierna, M. X., Gutierrez-Ramos, J.-C., Coyle, A. J., Garside, P. and Lawrence, C. E. (2004) Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis. European Journal of Immunology, 34, pp. 2854-2862. (doi: 10.1002/eji.200324364) (PMID:5368302)

2003

Boitelle, A., Scales, H. E. , Di Lorenzo, C., Devaney, E. , Kennedy, M. W. , Garside, P. and Lawrence, C. E. (2003) Investigating the impact of helminth products on immune responsiveness using a TCR transgenic adoptive transfer system. Journal of Immunology, 171(1), pp. 447-454. (doi: 10.4049/jimmunol.171.1.447) (PMID:12817029)

Articles

Camargo da Rosa, L. , Scales, H. E. , Benson, R. A. , Brewer, J. M. , McInnes, I. B. and Garside, P. (2024) The effect of abatacept on T cell activation is not long-lived in vivo. Discovery Immunology, 3(1), kyad029. (doi: 10.1093/discim/kyad029)

Audshasai, T. et al. (2022) Streptococcus pneumoniae rapidly translocate from the nasopharynx through the cribriform plate to invade the outer meninges. mBio, 13(4), e0102422. (doi: 10.1128/mbio.01024-22) (PMID:35924840) (PMCID:PMC9426477)

Prendergast, C. T., Benson, R. A. , Scales, H. E. , Bonilha, C. S., Cole, J. J., McInnes, I. , Brewer, J. M. and Garside, P. (2022) Dissecting the molecular control of immune cell accumulation in the inflamed joint. JCI Insight, 7(7), e151281. (doi: 10.1172/jci.insight.151281) (PMID:35192549) (PMCID:PMC9057592)

Camargo da Rosa, L. , Scales, H. E. , Makhija, S., Sutherland, K., Benson, R. A. , Brewer, J. M. and Garside, P. (2022) Revealing stromal and lymphoid sources of Col3a1-expression during inflammation using a novel reporter mouse. Discovery Immunology, 1(1), kyac008. (doi: 10.1093/discim/kyac008)

Meehan, G. R. , Scales, H. E. , McInnes, I. B. , Brewer, J. M. and Garside, P. (2022) Orally administered antigen can reduce or exacerbate pathology in an animal model of inflammatory arthritis dependent upon the timing of administration. Immunotherapy Advances, 2(1), ltac020. (doi: 10.1093/immadv/ltac020) (PMID:36268500) (PMCID:PMC9579813)

Bonilha, C. S., Benson, R. A. , Scales, H. E. , Brewer, J. M. and Garside, P. (2021) Junctional adhesion molecule-A on dendritic cells regulates Th1 differentiation. Immunology Letters, 235, pp. 32-40. (doi: 10.1016/j.imlet.2021.05.001) (PMID:34000305)

De Lorenzo, G. et al. (2021) Zika virus-like particles bearing covalent dimer of envelope protein protect mice from lethal challenge. Journal of Virology, 95(1), e01415-20. (doi: 10.1128/JVI.01415-20) (PMID:33028720) (PMCID:PMCID: PMC7737734)

Meehan, G. R. , Scales, H. E. , Osii, R., De Niz, M., Lawton, J. C., Marti, M. , Garside, P. , Craig, A. and Brewer, J. M. (2020) Developing a xenograft model of human vasculature in the mouse ear pinna. Scientific Reports, 10, 2058. (doi: 10.1038/s41598-020-58650-y) (PMID:32029768) (PMCID:PMC7004987)

Hayes, A. J. et al. (2019) Spatiotemporal modeling of the key migratory events during the initiation of adaptive immunity. Frontiers in Immunology, 10, 598. (doi: 10.3389/fimmu.2019.00598) (PMID:31024523) (PMCID:PMC6460458)

Scales, H. E. et al. (2018) A novel cellular pathway of antigen presentation and CD4 T cell activation in vivo. Frontiers in Immunology, 9, 2684. (doi: 10.3389/fimmu.2018.02684)

Noonan, J. et al. (2018) In vivo multiplex molecular imaging of vascular inflammation using surface-enhanced Raman spectroscopy. Theranostics, 8(22), pp. 6195-6209. (doi: 10.7150/thno.28665) (PMID:30613292) (PMCID:PMC6299693)

Stephen, J., Scales, H.E. , Benson, R.A. , Erben, D., Garside, P. and Brewer, J.M. (2017) Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity. npj Vaccines, 2, 1. (doi: 10.1038/s41541-016-0001-5) (PMID:29263862) (PMCID:PMC5604741)

Scales, H. E. , Ierna, M., Smith, K. M., Ross, K., Meiklejohn, G. R., Patterson-Kane, J. C., McInnes, I. B., Brewer, J. M. , Garside, P. and Maffia, P. (2016) Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging. Rheumatology, 55(3), pp. 564-572. (doi: 10.1093/rheumatology/kev361) (PMID:26475798)

Ierna, M., Kerr, A., Scales, H. , Berge, K. and Griinari, M. (2010) Supplementation of diet with krill oil protects against experimental rheumatoid arthritis. BMC Musculoskeletal Disorders, 11(1), 136. (doi: 10.1186/1471-2474-11-136) (PMID:20587038) (PMCID:PMC2907316)

Ierna, M.X., Scales, H.E. , Mueller, C. and Lawrence, C.E. (2009) Transmembrane tumor necrosis factor alpha is required for enteropathy and is sufficient to promote parasite expulsion in gastrointestinal helminth infection. Infection and Immunity, 77(9), pp. 3879-3885. (doi: 10.1128/IAI.01461-08) (PMID:19564380) (PMCID:PMC2737992)

Michels, C. E., Scales, H. E. , Saunders, K. A., McGowan, S., Brombracher, F., Alexander, J. and Lawrence, C. E. (2008) Neither interleukin-4 receptor α expression on CD4+ T cells, or macrophages and neutrophils is required for protective immunity to Trichinella spiralis. Immunology, 128(1pt2), e385-e394. (doi: 10.1111/j.1365-2567.2008.02987.x) (PMID:19191917)

Ierna, M.X., Scales, H.E. , Saunders, K.L. and Lawrence, C.E. (2008) Mast cell production of IL-4 and TNF may be required for protective and pathological responses in gastrointestinal helminth infection. Mucosal Immunology, 1, pp. 147-155. (doi: 10.1038/mi.2007.16) (PMID:19079172)

Scales, H.E. , Ierna, M.X. and Lawrence, C.E. (2007) The role of IL-4, IL-13 and IL-4Rα in the development of protective and pathological responses to Trichinella spiralis. Parasite Immunology, 29(2), pp. 81-91. (doi: 10.1111/j.1365-3024.2006.00920.x) (PMID:17241396)

Mann, J. F.S., Scales, H. E. , Shakir, E., Alexander, J., Carter, K. C., Mullen, A. B. and Ferro, V. A. (2006) Oral delivery of tetanus toxoid using vesicles containing bile salts (bilosomes) induces significant systemic and mucosal immunity. Methods, 38(2), 90 - 95. (doi: 10.1016/j.ymeth.2005.11.002) (PMID:16414269)

Ierna, M. X., Scales, H. E. , Schwarz, H., Bunce, C., McIlgorm, A., Garside, P. and Lawrence, C. E. (2006) OX40 interactions in gastrointestinal nematode infection. Immunology, 117(1), pp. 108-116. (doi: 10.1111/j.1365-2567.2005.02271.x) (PMID:16423046)

Boitelle, A., Di Lorenzo, C., Scales, H.E. , Devaney, E. , Kennedy, M.W., Garside, P. and Lawrence, C.E. (2005) Contrasting effects of acute and chronic gastro-intestinal helminth infections on a heterologous immune response in a transgenic adoptive transfer model. International Journal for Parasitology, 35(7), pp. 765-775. (doi: 10.1016/j.ijpara.2005.02.013) (PMID:15893319)

Scales, H. E. , Ierna, M. X., Gutierrez-Ramos, J.-C., Coyle, A. J., Garside, P. and Lawrence, C. E. (2004) Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis. European Journal of Immunology, 34, pp. 2854-2862. (doi: 10.1002/eji.200324364) (PMID:5368302)

Boitelle, A., Scales, H. E. , Di Lorenzo, C., Devaney, E. , Kennedy, M. W. , Garside, P. and Lawrence, C. E. (2003) Investigating the impact of helminth products on immune responsiveness using a TCR transgenic adoptive transfer system. Journal of Immunology, 171(1), pp. 447-454. (doi: 10.4049/jimmunol.171.1.447) (PMID:12817029)