2024

Wale, K. R., O'Boyle, N., McHugh, R. , Serrano, E. , Mark, D. , Douce, G. R. , Connolly, J. P.R. and Roe, A. J. (2024) A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens. PLoS Pathogens, 20(10), e101245. (doi: 10.1371/journal.ppat.1012451) (PMID:39405360) (PMCID:PMC11508082)

2023

Su Juan Chee, M., Serrano, E. , Ning Chiang, Y., Harling-Lee, J., Man, R., Bacigalupe, R., Ross Fitzgerald, J., Penades, J. R. and Chen, J. (2023) Dual pathogenicity island transfer by piggybacking lateral transduction. Cell, 186(16), 3414-3426.e16. (doi: 10.1016/j.cell.2023.07.001) (PMID:37541198)

Serrano, E. (2023) A New Twist on Drug Design: AdhE Spirosomes as Cross Species Anti Virulence Targets. Microbiology Society Annual Conference 2023, Birmingham, UK, 17-20 April 2023.

Serrano, E. (2023) A New Twist on Drug Design: AdhE Spirosomes as Cross Species Anti Virulence targets. Physics of Life 2023, Harrogate, UK, 27-30 March 2023.

2022

Connolly, J. P.R., Turner, N. C.A., Serrano, E. , Roe, A. J. , Rimbi, P. T., Browning, D. F. and O’Boyle, N. (2022) Control of resistance against bacteriophage killing by a metabolic regulator in meningitis-associated Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America, 119(45), e221029911. (doi: 10.1073/pnas.2210299119) (PMID:36322762) (PMCID:PMC9659370)

Serrano, E. (2022) A New Twist on Drug Design: AdhE Spirosomes as Cross Species Anti Virulence Targets. 25th International Analytical Ultracentrifugation Workshop and Symposium (AUC 2022), Lethbridge, AB, Canada, 10-15 Jul 2022.

Serrano, E. (2022) A New Twist on Drug Design: AdhE Spirosomes as Cross Species Anti Virulence Targets. British Biophysical Society Biennial Meeting, Galway, Ireland, 29 Jun - 01 Jul 2022.

Ramos, C., Hernández-Tamayo, R., López-Sanz, M., Carrasco, B., Serrano, E. , Alonso, J. C., Graumann, P. L. and Ayora, S. (2022) The RecD2 helicase balances RecA activities. Nucleic Acids Research, 50(6), pp. 3432-3444. (doi: 10.1093/nar/gkac131) (PMID:35234892) (PMCID:PMC8989531)

2021

Serrano, E. , Torres, R. and Alonso, J. C. (2021) Nucleoid‐associated Rok differentially affects chromosomal transformation on Bacillus subtilis recombination‐deficient cells. Environmental Microbiology, 23(6), pp. 3318-3331. (doi: 10.1111/1462-2920.15562) (PMID:33973337)

Serrano, E. , Ramos, C., Alonso, J. C. and Ayora, S. (2021) Recombination proteins differently control the acquisition of homeologous DNA during Bacillus subtilis natural chromosomal transformation. Environmental Microbiology, 23(1), pp. 512-524. (doi: 10.1111/1462-2920.15342) (PMID:33264457)

2020

Singh, P. K. et al. (2020) Reversible regulation of conjugation of Bacillus subtilis plasmid pLS20 by the quorum sensing peptide responsive anti-repressor RappLS20. Nucleic Acids Research, 48(19), pp. 10785-10801. (doi: 10.1093/nar/gkaa797) (PMID:33045732) (PMCID:PMC7641744)

Romero, H., Serrano, E. , Hernández-Tamayo, R., Carrasco, B., Cárdenas, P. P., Ayora, S., Graumann, P. L. and Alonso, J. C. (2020) Bacillus subtilis RarA acts as a positive RecA accessory protein. Frontiers in Microbiology, 11, 92. (doi: 10.3389/fmicb.2020.00092) (PMID:32117122) (PMCID:PMC7031210)

Serrano, E. , Ramos, C., Ayora, S. and Alonso, J. C. (2020) Viral SPP1 DNA is infectious in naturally competent Bacillus subtilis cells: inter- and intramolecular recombination pathways. Environmental Microbiology, 22(2), pp. 714-725. (doi: 10.1111/1462-2920.14908) (PMID:31876108)

2019

Torres, R., Serrano, E. and Alonso, J. C. (2019) Bacillus subtilis RecA interacts with and loads RadA/Sms to unwind recombination intermediates during natural chromosomal transformation. Nucleic Acids Research, 47(17), pp. 9198-9215. (doi: 10.1093/nar/gkz647) (PMID:31350886) (PMCID:PMC6755099)

Serrano, E. and Carrasco, B. (2019) Measurement of the length of the Integrated donor DNA during Bacillus subtilis natural chromosomal transformation. Bio-Protocol, 9(16), e3338. (doi: 10.21769/BioProtoc.3338) (PMID:33654843) (PMCID:PMC7854159)

Serrano, E. (2019) Bacillus subtilis RecA Interacts With and Loads RadA/Sms to Promote Branch Migration During Natural Chromosomal Transformation and DNA Repair. 42nd Congress of the Spanish Society of Biochemistry and Molecular Biology – SEBBM, Madrid, Spain, 16-19 Jul 2019.

Torres Sánchez, R., Serrano Álvarez, E. and Alonso Navarro, J. C. (2019) Bacillus subtilis RecA Interacts With and Loads RadA/Sms to Promote Branch Migration During Natural Chromosomal Transformation and DNA Repair. 8th Congress of European Microbiologists, Glasgow, UK, 07-11 Jul 2019.

Gago-Córdoba, C., Val-Calvo, J., Miguel-Arribas, A., Serrano, E. , Singh, P. K., Abia, D., Wu, L. J. and Meijer, W. J.J. (2019) Surface exclusion revisited: function related to differential expression of the surface exclusion system of Bacillus subtilis plasmid pLS20. Frontiers in Microbiology, 10, 1502. (doi: 10.3389/fmicb.2019.01502) (PMID:31354647) (PMCID:PMC6635565)

Torres Sánchez, R., Serrano, E. and Alonso, J. C. (2019) Bacillus subtilis RecA Interacts With and Loads RadA/Sms to Promote Branch Migration During Natural Chromosomal Transformation and DNA Repair. Structural and Molecular Biology of the DNA Damage Response, Madrid, Spain, 20-22 May 2019.

Torres, R., Serrano, E. , Tramm, K. and Alonso, J. C. (2019) Bacillus subtilis RadA/Sms contributes to chromosomal transformation and DNA repair in concert with RecA and circumvents replicative stress in concert with DisA. DNA Repair, 77, pp. 45-57. (doi: 10.1016/j.dnarep.2019.03.002) (PMID:30877841)

Carrasco, B., Serrano, E. , Martín-González, A., Moreno-Herrero, F. and Alonso, J. C. (2019) Bacillus subtilis MutS modulates RecA-mediated DNA strand exchange between divergent DNA sequences. Frontiers in Microbiology, 10, 237. (doi: 10.3389/fmicb.2019.00237) (PMID:30814990) (PMCID:PMC6382021)

2018

Val-Calvo, J. et al. (2018) Novel regulatory mechanism of establishment genes of conjugative plasmids. Nucleic Acids Research, 46(22), pp. 11910-11926. (doi: 10.1093/nar/gky996) (PMID:30380104) (PMCID:PMC6294495)

Serrano, E. (2018) Similarities and Differences Between Natural Transformation (Chromosomal and Plasmid) and Viral Transfection in Competent Bacillus subtilis Cells. 5th Annual Meeting of Spanish Network of Bacteriophages and Transducer Elements (FAGOMA), Madrid, Spain, 22-23 Oct 2018.

Serrano, E. , Carrasco, B. and Alonso, J. C. (2018) RecA Regulation by RecU and DprA During Bacillus subtilis Natural Plasmid Transformation. 8th Congress of European Microbiologists, Glasgow, UK, 07-11 Jul 2019.

Serrano, E. , Carrasco, B., Gilmore, J. L., Takeyasu, K. and Alonso, J. C. (2018) RecA regulation by RecU and DprA During bacillus subtilis natural plasmid transformation. Frontiers in Microbiology, 9, 1514. (doi: 10.3389/fmicb.2018.01514) (PMID:30050509) (PMCID:PMC6050356)

2017

Le, S., Serrano, E. , Kawamura, R., Carrasco, B., Yan, J. and Alonso, J. C. (2017) Bacillus subtilis RecA with DprA-SsbA antagonizes RecX function during natural transformation. Nucleic Acids Research, 45(15), pp. 8873-8885. (doi: 10.1093/nar/gkx583) (PMID:28911099) (PMCID:PMC5587729)

Serrano, E. (2017) Bacillus subtilis DisA y RadA Cooperate With Holliday Junction Processing Proteins in the Rescue of Stalled Replication Forks. FEMS 7th Congress of European Microbiologists, Valencia, Spain, 09-13 Jul 2017.

Gándara, C., de Lucena, D. K.C., Torres, R., Serrano, E. , Altenburger, S., Graumann, P. L. and Alonso, J. C. (2017) Activity and in vivo dynamics of Bacillus subtilis DisA are affected by RadA/Sms and by Holliday junction-processing proteins. DNA Repair, 55, pp. 17-30. (doi: 10.1016/j.dnarep.2017.05.002) (PMID:28511132)

Serrano, E. (2017) Bacillus subtilis MutS Modulates Non-polar Recombination Between Divergent DNA Sequences. 19th International Conference on Bacillus and Gram-Positive Bacteria, Berlin, Germany, 11-15 Jun 2017.

Carrasco, B., Cárdenas, P. P., Serrano, E. , Torres, R., Seco, E. M., Ayora, S. and Alonso, J. C. (2017) Dynamics of DNA double-strand break repair in Bacillus subtilis. In: Graumann, P. L. (ed.) Bacillus: Cellular and Molecular Biology. Third Edition. Caister Academic Press: Norfolk, UK, pp. 35-66. ISBN 9781910190579 (doi: 10.21775/9781910190579-02)

2016

Carrasco, B., Serrano, E. , Sánchez, H., Wyman, C. and Alonso, J. C. (2016) Chromosomal transformation in Bacillus subtilis is a non-polar recombination reaction. Nucleic Acids Research, 44(6), pp. 2754-2768. (doi: 10.1093/nar/gkv1546) (PMID:26786319) (PMCID:PMC4824099)

2015

Carrasco, B., Yadav, T., Serrano, E. and Alonso, J. C. (2015) Bacillus subtilisRecO and SsbA are crucial for RecA-mediated recombinational DNA repair. Nucleic Acids Research, 43(12), pp. 5984-5997. (doi: 10.1093/nar/gkv545) (PMID:26001966) (PMCID:PMC4499154)

2014

Yadav, T., Carrasco, B., Serrano, E. and Alonso, J. C. (2014) Roles of bacillus subtilis Dpra and Ssba in RecA-mediated genetic recombination. Journal of Biological Chemistry, 289(40), pp. 27640-27652. (doi: 10.1074/jbc.M114.577924) (PMID:25138221) (PMCID:PMC4183802)

2012

Serrano, E. (2012) Transcriptional Regulation of the Conjugation Operon of Bacillus subtilis Plasmid pLS20. Cell Cycle: the Challenge to Coordinate Genome Stability and Morphogenesis, Sep 2012.

Articles

Wale, K. R., O'Boyle, N., McHugh, R. , Serrano, E. , Mark, D. , Douce, G. R. , Connolly, J. P.R. and Roe, A. J. (2024) A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens. PLoS Pathogens, 20(10), e101245. (doi: 10.1371/journal.ppat.1012451) (PMID:39405360) (PMCID:PMC11508082)

Su Juan Chee, M., Serrano, E. , Ning Chiang, Y., Harling-Lee, J., Man, R., Bacigalupe, R., Ross Fitzgerald, J., Penades, J. R. and Chen, J. (2023) Dual pathogenicity island transfer by piggybacking lateral transduction. Cell, 186(16), 3414-3426.e16. (doi: 10.1016/j.cell.2023.07.001) (PMID:37541198)

Connolly, J. P.R., Turner, N. C.A., Serrano, E. , Roe, A. J. , Rimbi, P. T., Browning, D. F. and O’Boyle, N. (2022) Control of resistance against bacteriophage killing by a metabolic regulator in meningitis-associated Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America, 119(45), e221029911. (doi: 10.1073/pnas.2210299119) (PMID:36322762) (PMCID:PMC9659370)

Ramos, C., Hernández-Tamayo, R., López-Sanz, M., Carrasco, B., Serrano, E. , Alonso, J. C., Graumann, P. L. and Ayora, S. (2022) The RecD2 helicase balances RecA activities. Nucleic Acids Research, 50(6), pp. 3432-3444. (doi: 10.1093/nar/gkac131) (PMID:35234892) (PMCID:PMC8989531)

Serrano, E. , Torres, R. and Alonso, J. C. (2021) Nucleoid‐associated Rok differentially affects chromosomal transformation on Bacillus subtilis recombination‐deficient cells. Environmental Microbiology, 23(6), pp. 3318-3331. (doi: 10.1111/1462-2920.15562) (PMID:33973337)

Serrano, E. , Ramos, C., Alonso, J. C. and Ayora, S. (2021) Recombination proteins differently control the acquisition of homeologous DNA during Bacillus subtilis natural chromosomal transformation. Environmental Microbiology, 23(1), pp. 512-524. (doi: 10.1111/1462-2920.15342) (PMID:33264457)

Singh, P. K. et al. (2020) Reversible regulation of conjugation of Bacillus subtilis plasmid pLS20 by the quorum sensing peptide responsive anti-repressor RappLS20. Nucleic Acids Research, 48(19), pp. 10785-10801. (doi: 10.1093/nar/gkaa797) (PMID:33045732) (PMCID:PMC7641744)

Romero, H., Serrano, E. , Hernández-Tamayo, R., Carrasco, B., Cárdenas, P. P., Ayora, S., Graumann, P. L. and Alonso, J. C. (2020) Bacillus subtilis RarA acts as a positive RecA accessory protein. Frontiers in Microbiology, 11, 92. (doi: 10.3389/fmicb.2020.00092) (PMID:32117122) (PMCID:PMC7031210)

Serrano, E. , Ramos, C., Ayora, S. and Alonso, J. C. (2020) Viral SPP1 DNA is infectious in naturally competent Bacillus subtilis cells: inter- and intramolecular recombination pathways. Environmental Microbiology, 22(2), pp. 714-725. (doi: 10.1111/1462-2920.14908) (PMID:31876108)

Torres, R., Serrano, E. and Alonso, J. C. (2019) Bacillus subtilis RecA interacts with and loads RadA/Sms to unwind recombination intermediates during natural chromosomal transformation. Nucleic Acids Research, 47(17), pp. 9198-9215. (doi: 10.1093/nar/gkz647) (PMID:31350886) (PMCID:PMC6755099)

Serrano, E. and Carrasco, B. (2019) Measurement of the length of the Integrated donor DNA during Bacillus subtilis natural chromosomal transformation. Bio-Protocol, 9(16), e3338. (doi: 10.21769/BioProtoc.3338) (PMID:33654843) (PMCID:PMC7854159)

Gago-Córdoba, C., Val-Calvo, J., Miguel-Arribas, A., Serrano, E. , Singh, P. K., Abia, D., Wu, L. J. and Meijer, W. J.J. (2019) Surface exclusion revisited: function related to differential expression of the surface exclusion system of Bacillus subtilis plasmid pLS20. Frontiers in Microbiology, 10, 1502. (doi: 10.3389/fmicb.2019.01502) (PMID:31354647) (PMCID:PMC6635565)

Torres, R., Serrano, E. , Tramm, K. and Alonso, J. C. (2019) Bacillus subtilis RadA/Sms contributes to chromosomal transformation and DNA repair in concert with RecA and circumvents replicative stress in concert with DisA. DNA Repair, 77, pp. 45-57. (doi: 10.1016/j.dnarep.2019.03.002) (PMID:30877841)

Carrasco, B., Serrano, E. , Martín-González, A., Moreno-Herrero, F. and Alonso, J. C. (2019) Bacillus subtilis MutS modulates RecA-mediated DNA strand exchange between divergent DNA sequences. Frontiers in Microbiology, 10, 237. (doi: 10.3389/fmicb.2019.00237) (PMID:30814990) (PMCID:PMC6382021)

Val-Calvo, J. et al. (2018) Novel regulatory mechanism of establishment genes of conjugative plasmids. Nucleic Acids Research, 46(22), pp. 11910-11926. (doi: 10.1093/nar/gky996) (PMID:30380104) (PMCID:PMC6294495)

Serrano, E. , Carrasco, B., Gilmore, J. L., Takeyasu, K. and Alonso, J. C. (2018) RecA regulation by RecU and DprA During bacillus subtilis natural plasmid transformation. Frontiers in Microbiology, 9, 1514. (doi: 10.3389/fmicb.2018.01514) (PMID:30050509) (PMCID:PMC6050356)

Le, S., Serrano, E. , Kawamura, R., Carrasco, B., Yan, J. and Alonso, J. C. (2017) Bacillus subtilis RecA with DprA-SsbA antagonizes RecX function during natural transformation. Nucleic Acids Research, 45(15), pp. 8873-8885. (doi: 10.1093/nar/gkx583) (PMID:28911099) (PMCID:PMC5587729)

Gándara, C., de Lucena, D. K.C., Torres, R., Serrano, E. , Altenburger, S., Graumann, P. L. and Alonso, J. C. (2017) Activity and in vivo dynamics of Bacillus subtilis DisA are affected by RadA/Sms and by Holliday junction-processing proteins. DNA Repair, 55, pp. 17-30. (doi: 10.1016/j.dnarep.2017.05.002) (PMID:28511132)

Carrasco, B., Serrano, E. , Sánchez, H., Wyman, C. and Alonso, J. C. (2016) Chromosomal transformation in Bacillus subtilis is a non-polar recombination reaction. Nucleic Acids Research, 44(6), pp. 2754-2768. (doi: 10.1093/nar/gkv1546) (PMID:26786319) (PMCID:PMC4824099)

Carrasco, B., Yadav, T., Serrano, E. and Alonso, J. C. (2015) Bacillus subtilisRecO and SsbA are crucial for RecA-mediated recombinational DNA repair. Nucleic Acids Research, 43(12), pp. 5984-5997. (doi: 10.1093/nar/gkv545) (PMID:26001966) (PMCID:PMC4499154)

Yadav, T., Carrasco, B., Serrano, E. and Alonso, J. C. (2014) Roles of bacillus subtilis Dpra and Ssba in RecA-mediated genetic recombination. Journal of Biological Chemistry, 289(40), pp. 27640-27652. (doi: 10.1074/jbc.M114.577924) (PMID:25138221) (PMCID:PMC4183802)

Book Sections

Carrasco, B., Cárdenas, P. P., Serrano, E. , Torres, R., Seco, E. M., Ayora, S. and Alonso, J. C. (2017) Dynamics of DNA double-strand break repair in Bacillus subtilis. In: Graumann, P. L. (ed.) Bacillus: Cellular and Molecular Biology. Third Edition. Caister Academic Press: Norfolk, UK, pp. 35-66. ISBN 9781910190579 (doi: 10.21775/9781910190579-02)

Conference or Workshop Item

Serrano, E. (2023) A New Twist on Drug Design: AdhE Spirosomes as Cross Species Anti Virulence Targets. Microbiology Society Annual Conference 2023, Birmingham, UK, 17-20 April 2023.

Serrano, E. (2023) A New Twist on Drug Design: AdhE Spirosomes as Cross Species Anti Virulence targets. Physics of Life 2023, Harrogate, UK, 27-30 March 2023.

Serrano, E. (2022) A New Twist on Drug Design: AdhE Spirosomes as Cross Species Anti Virulence Targets. 25th International Analytical Ultracentrifugation Workshop and Symposium (AUC 2022), Lethbridge, AB, Canada, 10-15 Jul 2022.

Serrano, E. (2022) A New Twist on Drug Design: AdhE Spirosomes as Cross Species Anti Virulence Targets. British Biophysical Society Biennial Meeting, Galway, Ireland, 29 Jun - 01 Jul 2022.

Serrano, E. (2019) Bacillus subtilis RecA Interacts With and Loads RadA/Sms to Promote Branch Migration During Natural Chromosomal Transformation and DNA Repair. 42nd Congress of the Spanish Society of Biochemistry and Molecular Biology – SEBBM, Madrid, Spain, 16-19 Jul 2019.

Torres Sánchez, R., Serrano Álvarez, E. and Alonso Navarro, J. C. (2019) Bacillus subtilis RecA Interacts With and Loads RadA/Sms to Promote Branch Migration During Natural Chromosomal Transformation and DNA Repair. 8th Congress of European Microbiologists, Glasgow, UK, 07-11 Jul 2019.

Torres Sánchez, R., Serrano, E. and Alonso, J. C. (2019) Bacillus subtilis RecA Interacts With and Loads RadA/Sms to Promote Branch Migration During Natural Chromosomal Transformation and DNA Repair. Structural and Molecular Biology of the DNA Damage Response, Madrid, Spain, 20-22 May 2019.

Serrano, E. (2018) Similarities and Differences Between Natural Transformation (Chromosomal and Plasmid) and Viral Transfection in Competent Bacillus subtilis Cells. 5th Annual Meeting of Spanish Network of Bacteriophages and Transducer Elements (FAGOMA), Madrid, Spain, 22-23 Oct 2018.

Serrano, E. , Carrasco, B. and Alonso, J. C. (2018) RecA Regulation by RecU and DprA During Bacillus subtilis Natural Plasmid Transformation. 8th Congress of European Microbiologists, Glasgow, UK, 07-11 Jul 2019.

Serrano, E. (2017) Bacillus subtilis DisA y RadA Cooperate With Holliday Junction Processing Proteins in the Rescue of Stalled Replication Forks. FEMS 7th Congress of European Microbiologists, Valencia, Spain, 09-13 Jul 2017.

Serrano, E. (2017) Bacillus subtilis MutS Modulates Non-polar Recombination Between Divergent DNA Sequences. 19th International Conference on Bacillus and Gram-Positive Bacteria, Berlin, Germany, 11-15 Jun 2017.

Serrano, E. (2012) Transcriptional Regulation of the Conjugation Operon of Bacillus subtilis Plasmid pLS20. Cell Cycle: the Challenge to Coordinate Genome Stability and Morphogenesis, Sep 2012.