Dr Diego Cantoni
- Research Associate (Virology)
https://orcid.org/0000-0001-8527-7719Publications
2023
Cantoni, D. et al. (2023) Correlation between pseudotyped virus and authentic virus neutralisation assays, a systematic review and meta-analysis of the literature. Frontiers in Immunology, 14, 1184362. (doi: 10.3389/fimmu.2023.1184362) (PMID:37790941) (PMCID:PMC10544934)
Záhonová, K. et al. (2023) Evolutionary analysis of cellular reduction and anaerobicity in the hyper-prevalent gut microbe Blastocystis. Current Biology, 33(12), 2449-2464.e8. (doi: 10.1016/j.cub.2023.05.025) (PMID:37267944)
Aguinam, E. T. et al. (2023) Differential T-cell and antibody responses induced by mRNA versus adenoviral vectored COVID-19 vaccines in patients with immunodeficiencies. Journal of Allergy and Clinical Immunology: Global, 2(2), 100091. (doi: 10.1016/j.jacig.2023.100091) (PMID:37038555) (PMCID:PMC10015741)
Cantoni, D. and Grove, J. (2023) Low hanging fruit for combatting SARS‐CoV‐2? EMBO Reports, 24(4), e56979. (doi: 10.15252/embr.202356979) (PMID:36876512) (PMCID:PMC10074046)
Horvath, D. et al. (2023) Novel intranasal vaccine targeting SARS-CoV-2 receptor binding domain to mucosal microfold cells and adjuvanted with TLR3 agonist Riboxxim™ elicits strong antibody and T-cell responses in mice. Scientific Reports, 13(1), 4648. (doi: 10.1038/s41598-023-31198-3) (PMID:36944687) (PMCID:PMC10029786)
Nadesalingam, A. et al. (2023) Vaccination and protective immunity to SARS-CoV-2 omicron variants in people with immunodeficiencies. Lancet Microbe, 4(2), e58-e59. (doi: 10.1016/s2666-5247(22)00297-x) (PMID:36332646) (PMCID:PMC9625114)
Cantoni, D. et al. (2023) Analysis of antibody neutralisation activity against SARS-CoV-2 variants and seasonal human coronaviruses NL63, HKU1, and 229E induced by three different COVID-19 vaccine platforms. Vaccines, 11(1), 58. (doi: 10.3390/vaccines11010058) (PMID:36679903) (PMCID:PMC9864028)
2022
Atti, A. et al. (2022) Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: A nested case-control within the SIREN study. Journal of Infection, 85(5), pp. 545-556. (doi: 10.1016/j.jinf.2022.09.004) (PMID:36089104) (PMCID:PMC9458758)
Cantoni, D. et al. (2022) Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike. EMBO Reports, 23(10), e54322. (doi: 10.15252/embr.202154322) (PMID:35999696) (PMCID:PMC9535765)
Wells, D. A. et al. (2022) Human seasonal coronavirus neutralization and COVID‐19 severity. Journal of Medical Virology, 94(10), pp. 4820-4829. (doi: 10.1002/jmv.27937) (PMID:35705514) (PMCID:PMC9349487)
Willett, B. J. et al. (2022) Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology, 7, 1709. (doi: 10.1038/s41564-022-01241-6) (PMID:36114232) (PMCID:PMC9483304)
Ruiz, M. J. et al. (2022) Persistent but dysfunctional mucosal SARS-CoV-2-specific IgA and low lung IL-1β associate with COVID-19 fatal outcome: A cross-sectional analysis. Frontiers in Immunology, 13, (doi: 10.3389/fimmu.2022.842468) (PMID:36248831) (PMCID:PMC9560774)
Varela, L., Hendry, A. C., Cassar, J., Martin-Escolano, R., Cantoni, D. , Ossa, F., Edwards, J. C., Abdul-Salam, V. and Ortega-Roldan, J. L. (2022) A Zn2+-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels. Journal of Cell Science, 135(15), jcs259704. (doi: 10.1242/jcs.259704) (PMID:35833483) (PMCID:PMC9511705)
Willett, B. J. et al. (2022) SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology, 7(8), pp. 1161-1179. (doi: 10.1038/s41564-022-01143-7) (PMID:35798890) (PMCID:PMC9352574)
Cantoni, D. et al. (2022) Localization and functional characterization of the alternative oxidase in Naegleria. Journal of Eukaryotic Microbiology, 69(4), e12908. (doi: 10.1111/jeu.12908) (PMID:35322502) (PMCID:PMC9540462)
Cantoni, D. et al. (2022) Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients. Communications Biology, 5(1), 409. (doi: 10.1038/s42003-022-03325-9) (PMID:35505237) (PMCID:PMC9065041)
Cantoni, D. et al. (2022) Neutralisation hierarchy of SARS-CoV-2 variants of concern using standardised, quantitative neutralisation assays reveals a correlation with disease severity; towards deciphering protective antibody thresholds. Frontiers in Immunology, 13, 773982. (doi: 10.3389/fimmu.2022.773982) (PMID:35330908) (PMCID:PMC8940306)
Das, J. et al. (2022) Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients. PLoS ONE, 17(2), e0261979. (doi: 10.1371/journal.pone.0261979) (PMID:35192617) (PMCID:PMC8863217)
2021
Castillo-Olivares, J. et al. (2021) Analysis of serological biomarkers of SARS-CoV-2 infection in convalescent samples from severe, moderate and mild COVID-19 cases. Frontiers in Immunology, 12, 748291. (doi: 10.3389/fimmu.2021.748291) (PMID:34867975) (PMCID:PMC8640495)
Genova, C. et al. (2021) Production, titration, neutralisation, storage and lyophilisation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lentiviral pseudotypes. Bio-protocol, 11(21), e4236. (doi: 10.21769/bioprotoc.4236) (PMID:34859134) (PMCID:PMC8595416)
Siracusano, G. et al. (2021) Profiling antibody response patterns in COVID-19: Spike S1-reactive IgA signature in the evolution of SARS-CoV-2 infection. Frontiers in Immunology, 12, 772239. (doi: 10.3389/fimmu.2021.772239) (PMID:34804064) (PMCID:PMC8595940)
Jinatham, V., Cantoni, D. M. , Brown, I. R., Vichaslip, T., Suwannahitatorn, P., Popluechai, S., Tsaousis, A. D. and Gentekaki, E. (2021) Prototheca bovis, a unicellular achlorophyllous trebouxiophyte green alga in the healthy human intestine. Journal of Medical Microbiology, 70(9), 001415. (doi: 10.1099/jmm.0.001415) (PMID:34486973)
Nadesalingam, A. et al. (2021) Paucity and discordance of neutralising antibody responses to SARS-CoV-2 VOCs in vaccinated immunodeficient patients and health-care workers in the UK. Lancet Microbe, 2(9), e416-e418. (doi: 10.1016/s2666-5247(21)00157-9) (PMID:34223399) (PMCID:PMC8238451)
Sampson, A. T. et al. (2021) Coronavirus pseudotypes for all circulating human coronaviruses for quantification of cross-neutralizing antibody responses. Viruses, 13(8), 1579. (doi: 10.3390/v13081579) (PMID:34452443) (PMCID:PMC8402765)
Articles
Cantoni, D. et al. (2023) Correlation between pseudotyped virus and authentic virus neutralisation assays, a systematic review and meta-analysis of the literature. Frontiers in Immunology, 14, 1184362. (doi: 10.3389/fimmu.2023.1184362) (PMID:37790941) (PMCID:PMC10544934)
Záhonová, K. et al. (2023) Evolutionary analysis of cellular reduction and anaerobicity in the hyper-prevalent gut microbe Blastocystis. Current Biology, 33(12), 2449-2464.e8. (doi: 10.1016/j.cub.2023.05.025) (PMID:37267944)
Aguinam, E. T. et al. (2023) Differential T-cell and antibody responses induced by mRNA versus adenoviral vectored COVID-19 vaccines in patients with immunodeficiencies. Journal of Allergy and Clinical Immunology: Global, 2(2), 100091. (doi: 10.1016/j.jacig.2023.100091) (PMID:37038555) (PMCID:PMC10015741)
Cantoni, D. and Grove, J. (2023) Low hanging fruit for combatting SARS‐CoV‐2? EMBO Reports, 24(4), e56979. (doi: 10.15252/embr.202356979) (PMID:36876512) (PMCID:PMC10074046)
Horvath, D. et al. (2023) Novel intranasal vaccine targeting SARS-CoV-2 receptor binding domain to mucosal microfold cells and adjuvanted with TLR3 agonist Riboxxim™ elicits strong antibody and T-cell responses in mice. Scientific Reports, 13(1), 4648. (doi: 10.1038/s41598-023-31198-3) (PMID:36944687) (PMCID:PMC10029786)
Nadesalingam, A. et al. (2023) Vaccination and protective immunity to SARS-CoV-2 omicron variants in people with immunodeficiencies. Lancet Microbe, 4(2), e58-e59. (doi: 10.1016/s2666-5247(22)00297-x) (PMID:36332646) (PMCID:PMC9625114)
Cantoni, D. et al. (2023) Analysis of antibody neutralisation activity against SARS-CoV-2 variants and seasonal human coronaviruses NL63, HKU1, and 229E induced by three different COVID-19 vaccine platforms. Vaccines, 11(1), 58. (doi: 10.3390/vaccines11010058) (PMID:36679903) (PMCID:PMC9864028)
Atti, A. et al. (2022) Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: A nested case-control within the SIREN study. Journal of Infection, 85(5), pp. 545-556. (doi: 10.1016/j.jinf.2022.09.004) (PMID:36089104) (PMCID:PMC9458758)
Cantoni, D. et al. (2022) Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike. EMBO Reports, 23(10), e54322. (doi: 10.15252/embr.202154322) (PMID:35999696) (PMCID:PMC9535765)
Wells, D. A. et al. (2022) Human seasonal coronavirus neutralization and COVID‐19 severity. Journal of Medical Virology, 94(10), pp. 4820-4829. (doi: 10.1002/jmv.27937) (PMID:35705514) (PMCID:PMC9349487)
Willett, B. J. et al. (2022) Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology, 7, 1709. (doi: 10.1038/s41564-022-01241-6) (PMID:36114232) (PMCID:PMC9483304)
Ruiz, M. J. et al. (2022) Persistent but dysfunctional mucosal SARS-CoV-2-specific IgA and low lung IL-1β associate with COVID-19 fatal outcome: A cross-sectional analysis. Frontiers in Immunology, 13, (doi: 10.3389/fimmu.2022.842468) (PMID:36248831) (PMCID:PMC9560774)
Varela, L., Hendry, A. C., Cassar, J., Martin-Escolano, R., Cantoni, D. , Ossa, F., Edwards, J. C., Abdul-Salam, V. and Ortega-Roldan, J. L. (2022) A Zn2+-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels. Journal of Cell Science, 135(15), jcs259704. (doi: 10.1242/jcs.259704) (PMID:35833483) (PMCID:PMC9511705)
Willett, B. J. et al. (2022) SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. Nature Microbiology, 7(8), pp. 1161-1179. (doi: 10.1038/s41564-022-01143-7) (PMID:35798890) (PMCID:PMC9352574)
Cantoni, D. et al. (2022) Localization and functional characterization of the alternative oxidase in Naegleria. Journal of Eukaryotic Microbiology, 69(4), e12908. (doi: 10.1111/jeu.12908) (PMID:35322502) (PMCID:PMC9540462)
Cantoni, D. et al. (2022) Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients. Communications Biology, 5(1), 409. (doi: 10.1038/s42003-022-03325-9) (PMID:35505237) (PMCID:PMC9065041)
Cantoni, D. et al. (2022) Neutralisation hierarchy of SARS-CoV-2 variants of concern using standardised, quantitative neutralisation assays reveals a correlation with disease severity; towards deciphering protective antibody thresholds. Frontiers in Immunology, 13, 773982. (doi: 10.3389/fimmu.2022.773982) (PMID:35330908) (PMCID:PMC8940306)
Das, J. et al. (2022) Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients. PLoS ONE, 17(2), e0261979. (doi: 10.1371/journal.pone.0261979) (PMID:35192617) (PMCID:PMC8863217)
Castillo-Olivares, J. et al. (2021) Analysis of serological biomarkers of SARS-CoV-2 infection in convalescent samples from severe, moderate and mild COVID-19 cases. Frontiers in Immunology, 12, 748291. (doi: 10.3389/fimmu.2021.748291) (PMID:34867975) (PMCID:PMC8640495)
Genova, C. et al. (2021) Production, titration, neutralisation, storage and lyophilisation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lentiviral pseudotypes. Bio-protocol, 11(21), e4236. (doi: 10.21769/bioprotoc.4236) (PMID:34859134) (PMCID:PMC8595416)
Siracusano, G. et al. (2021) Profiling antibody response patterns in COVID-19: Spike S1-reactive IgA signature in the evolution of SARS-CoV-2 infection. Frontiers in Immunology, 12, 772239. (doi: 10.3389/fimmu.2021.772239) (PMID:34804064) (PMCID:PMC8595940)
Jinatham, V., Cantoni, D. M. , Brown, I. R., Vichaslip, T., Suwannahitatorn, P., Popluechai, S., Tsaousis, A. D. and Gentekaki, E. (2021) Prototheca bovis, a unicellular achlorophyllous trebouxiophyte green alga in the healthy human intestine. Journal of Medical Microbiology, 70(9), 001415. (doi: 10.1099/jmm.0.001415) (PMID:34486973)
Nadesalingam, A. et al. (2021) Paucity and discordance of neutralising antibody responses to SARS-CoV-2 VOCs in vaccinated immunodeficient patients and health-care workers in the UK. Lancet Microbe, 2(9), e416-e418. (doi: 10.1016/s2666-5247(21)00157-9) (PMID:34223399) (PMCID:PMC8238451)
Sampson, A. T. et al. (2021) Coronavirus pseudotypes for all circulating human coronaviruses for quantification of cross-neutralizing antibody responses. Viruses, 13(8), 1579. (doi: 10.3390/v13081579) (PMID:34452443) (PMCID:PMC8402765)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Screening and characterisation of host receptor interactions by the filovirus secreted glycoproteins.
The Royal Society of Edinburgh
2024 - 2025
Research datasets
2024
Furnon, W. , Cowton, V. M., De Lorenzo, G. , Orton, R. , Herder, V. , Cantoni, D. , Ilia, G., Correa Mendonca, D. , Kerr, K., Allan, J., Upfold, N. , Meehan, G. R. , Bakshi, S., Das, U. R., Molina Arias, S., McElwee, M., Little, S., Logan, N., Kwok, K. , Smollett, K. , Willett, B. , Da Silva Filipe, A. , Robertson, D. L. , Grove, J. , Patel, A. H. and Palmarini, M. (2024) Phenotypic evolution of SARS-CoV-2 spike throughout the COVID-19 pandemic. [Data Collection]