Dr David Mark
- Research Associate (Bacteriology)
Publications
2024
Mark, D. R. , O'Boyle, N., Wale, K. R., Tucker, S. K., McHugh, R. E. and Roe, A. J. (2024) Aurodox inhibits type III secretion in multiple Gram-negative pathogens. Open Biology, 14(11), 240240. (doi: 10.1098/rsob.240240) (PMID:39591989) (PMCID:PMC11597412)
Wale, K. R., O'Boyle, N., McHugh, R. , Serrano, E. , Mark, D. , Douce, G. R. , Connolly, J. P.R. and Roe, A. J. (2024) A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens. PLoS Pathogens, 20(10), e101245. (doi: 10.1371/journal.ppat.1012451) (PMID:39405360) (PMCID:PMC11508082)
Mark, D. , Trolan, M., Douce, G., Roe, A. J. and McHugh, R. E. (2024) The enemy within: how pathogen-free are your commercial specific pathogen-free mice? bioRxiv, (doi: 10.1101/2024.07.05.602177)
Mark, D. , O’Boyle, N., Wale, K. R., Tucker, S. K., McHugh, R. E. and Roe, A. J. (2024) Aurodox, a polyketide from Streptomyces goldiniensis, inhibits transcription of the type III secretion system of multiple Gram-negative pathogens. bioRxiv, (doi: 10.1101/2024.04.19.589875)
2022
Feeney, M. A. et al. (2022) ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria. Microbial Genomics, 8(7), 000824. (doi: 10.1099/mgen.0.000824) (PMID:35775972) (PMCID:PMC9455695)
2021
Algora-Gallardo, L., Schniete, J. K., Mark, D. R. , Hunter, I. S. and Herron, P. R. (2021) Bilateral symmetry of linear streptomycete chromosomes. Microbial Genomics, 7(11), 000692. (doi: 10.1099/mgen.0.000692) (PMID:34779763) (PMCID:PMC8743542)
Zin, N. M., Ismail, A., Mark, D. R. , Westrop, G., Schniete, J. K. and Herron, P. R. (2021) Adaptation to endophytic lifestyle through genome reduction by Kitasatospora sp. SUK42. Frontiers in Bioengineering and Biotechnology, 9, 740722. (doi: 10.3389/fbioe.2021.740722) (PMID:34712653) (PMCID:PMC8545861)
Rauscher, R. et al. (2021) Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity. Proceedings of the National Academy of Sciences of the United States of America, 118(4), e201061211. (doi: 10.1073/pnas.2010612118) (PMID:33468668) (PMCID:PMC7848603)
2020
Prudence, S. M.M., Addington, E. , Castaño-Espriu, L., Mark, D. R. , Pintor-Escobar, L., Russell, A. H. and McLean, T. C. (2020) Advances in actinomycete research: an ActinoBase review of 2019. Microbiology, 166(8), pp. 683-694. (doi: 10.1099/mic.0.000944) (PMID:32558638) (PMCID:PMC7641383)
Articles
Mark, D. R. , O'Boyle, N., Wale, K. R., Tucker, S. K., McHugh, R. E. and Roe, A. J. (2024) Aurodox inhibits type III secretion in multiple Gram-negative pathogens. Open Biology, 14(11), 240240. (doi: 10.1098/rsob.240240) (PMID:39591989) (PMCID:PMC11597412)
Wale, K. R., O'Boyle, N., McHugh, R. , Serrano, E. , Mark, D. , Douce, G. R. , Connolly, J. P.R. and Roe, A. J. (2024) A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens. PLoS Pathogens, 20(10), e101245. (doi: 10.1371/journal.ppat.1012451) (PMID:39405360) (PMCID:PMC11508082)
Mark, D. , Trolan, M., Douce, G., Roe, A. J. and McHugh, R. E. (2024) The enemy within: how pathogen-free are your commercial specific pathogen-free mice? bioRxiv, (doi: 10.1101/2024.07.05.602177)
Mark, D. , O’Boyle, N., Wale, K. R., Tucker, S. K., McHugh, R. E. and Roe, A. J. (2024) Aurodox, a polyketide from Streptomyces goldiniensis, inhibits transcription of the type III secretion system of multiple Gram-negative pathogens. bioRxiv, (doi: 10.1101/2024.04.19.589875)
Feeney, M. A. et al. (2022) ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria. Microbial Genomics, 8(7), 000824. (doi: 10.1099/mgen.0.000824) (PMID:35775972) (PMCID:PMC9455695)
Algora-Gallardo, L., Schniete, J. K., Mark, D. R. , Hunter, I. S. and Herron, P. R. (2021) Bilateral symmetry of linear streptomycete chromosomes. Microbial Genomics, 7(11), 000692. (doi: 10.1099/mgen.0.000692) (PMID:34779763) (PMCID:PMC8743542)
Zin, N. M., Ismail, A., Mark, D. R. , Westrop, G., Schniete, J. K. and Herron, P. R. (2021) Adaptation to endophytic lifestyle through genome reduction by Kitasatospora sp. SUK42. Frontiers in Bioengineering and Biotechnology, 9, 740722. (doi: 10.3389/fbioe.2021.740722) (PMID:34712653) (PMCID:PMC8545861)
Rauscher, R. et al. (2021) Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity. Proceedings of the National Academy of Sciences of the United States of America, 118(4), e201061211. (doi: 10.1073/pnas.2010612118) (PMID:33468668) (PMCID:PMC7848603)
Prudence, S. M.M., Addington, E. , Castaño-Espriu, L., Mark, D. R. , Pintor-Escobar, L., Russell, A. H. and McLean, T. C. (2020) Advances in actinomycete research: an ActinoBase review of 2019. Microbiology, 166(8), pp. 683-694. (doi: 10.1099/mic.0.000944) (PMID:32558638) (PMCID:PMC7641383)