Dr Dagmara McGuinness
- Research Associate (Parasitology)
telephone:
(0) 141 330 5276
email:
Dagmara.McGuinness@glasgow.ac.uk
Wellcome Centre for Molecular Parasitology,, Institute of Infection, Immunity and Inflammation, 120 University Place, G12 8TA
Publications
2024
Nyirenda, J. et al. (2024) Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population. Nature Medicine, (doi: 10.1038/s41591-024-03354-3) (Early Online Publication)
Abrams, S. T. et al. (2024) Damage-associated cellular markers in the clinical and pathogenic profile of vaccine-induced immune thrombotic thrombocytopenia. Journal of Thrombosis and Haemostasis, 22(4), pp. 1145-1153. (doi: 10.1016/j.jtha.2023.12.008) (PMID:38103733)
2023
Nyirenda, J. et al. (2023) Spatially resolved single-cell atlas of the lung in fatal Covid19 in an African population reveals a distinct cellular signature and an interferon gamma dominated response. bioRxiv, (doi: 10.1101/2023.11.16.566964)
Craven, H., Erlandsson, H., McGuinness, D., McGuinness, D. , Mafra, D., Ijaz, U. Z. , Bergman, P., Shiels, P. G. and Stenvinkel, P. (2023) A normative microbiome is not restored following kidney transplantation. Clinical Science, 137(20), pp. 1563-1575. (doi: 10.1042/CS20230779) (PMID:37756543)
Panagiotou, N. , McGuinness, D., Jaminon, A. M.G., Mees, B., Selman, C. , Schurgers, L. and Shiels, P. G. (2023) Microvesicle-mediated tissue regeneration mitigates the effects of cellular ageing. Cells, 12(13), 1707. (doi: 10.3390/cells12131707) (PMID:37443741) (PMCID:PMC10340655)
2021
Mulvey, L., Wilkie, S. E., Borland, G., Griffiths, K., Sinclair, A., McGuinness, D., Watson, D. G. and Selman, C. (2021) Strain-specific metabolic responses to long-term caloric restriction in female ILSXISS recombinant inbred mice. Molecular and Cellular Endocrinology, 535, 111376. (doi: 10.1016/j.mce.2021.111376) (PMID:34246728) (PMCID:PMC8417819)
Craven, H. et al. (2021) Socioeconomic position links circulatory microbiota differences with biological age. Scientific Reports, 11, 12629. (doi: 10.1038/s41598-021-92042-0) (PMID:34135381) (PMCID:PMC8209159)
2020
Moxon, C. A. et al. (2020) Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria. Blood Advances, 4(13), pp. 2851-2864. (doi: 10.1182/bloodadvances.2019001258) (PMID:32579667) (PMCID:PMC7362376)
Moxon, C. A. , Gibbins, M. P. , McGuinness, D., Milner, D. A. and Marti, M. (2020) New insights into malaria pathogenesis. Annual Review of Pathology: Mechanisms of Disease, 15(1), pp. 315-343. (doi: 10.1146/annurev-pathmechdis-012419-032640) (PMID:31648610)
2019
de Kok, M. J. et al. (2019) The neglectable impact of delayed graft function on long-term graft survival in kidneys donated after circulatory death associates with superior organ resilience. Annals of Surgery, 270(5), pp. 877-883. (doi: 10.1097/SLA.0000000000003515) (PMID:31567503)
2018
Diaz-Albiter, H. M., Regnault, C., Alpizar-Sosa, E. A., McGuinness, D., Barrett, M. P. and Dillon, R. J. (2018) Non-invasive visualisation and identification of fluorescent. Wellcome Open Research, 3, 160. (doi: 10.12688/wellcomeopenres.14910.1) (PMID:30756095) (PMCID:PMC6367660)
McGuinness, D. et al. (2018) A molecular signature for delayed graft function. Aging Cell, 17(5), e12825. (doi: 10.1111/acel.12825) (PMID:30094915) (PMCID:PMC6156499)
Lakhdar, R., McGuinness, D., Drost, E. M., Shiels, P. G. , Bastos, R., MacNee, W. and Rabinovich, R. A. (2018) Role of accelerated ageing in limb muscle wasting of patients with COPD. International Journal of Chronic Obstructive Pulmonary Disease, 13, pp. 1987-1998. (doi: 10.2147/COPD.S155952) (PMID:29970961) (PMCID:PMC6022820)
2017
Shiels, P. G. , McGuinness, D., Eriksson, M., Kooman, J. P. and Stenvinkel, P. (2017) The role of epigenetics in renal ageing. Nature Reviews Nephrology, 13, pp. 471-482. (doi: 10.1038/nrneph.2017.78) (PMID:28626222)
Shiels, P. G. , Stenvinkel, P., Kooman, J. P. and McGuinness, D. (2017) Circulating markers of ageing and allostatic load: a slow train coming. Practical Laboratory Medicine, 7, pp. 49-54. (doi: 10.1016/j.plabm.2016.04.002) (PMID:28856219) (PMCID:PMC5574864)
Stenvinkel, P. et al. (2017) CDKN2A/p16INK4a expression is associated with vascular progeria in chronic kidney disease. Aging, 9(2), pp. 494-507. (doi: 10.18632/aging.101173) (PMID:28192277)
2016
Khojah, S. M., Payne, A. P., McGuinness, D. and Shields, P. G. (2016) Segmental aging underlies the development of a Parkinson phenotype in the AS/AGU rat. Cells, 5(4), 38. (doi: 10.3390/cells5040038) (PMID:27763519) (PMCID:PMC5187522)
Luttropp, K. et al. (2016) Increased telomere attrition following renal transplantation: impact of anti-metabolite therapy. Transplantation Direct, 2(12), e116. (doi: 10.1097/TXD.0000000000000629) (PMID:27990481) (PMCID:PMC5142370)
McGuinness, D., Anthony, D. F., Moulisova, V. , MacDonald, A. I., Macintyre, A., Thomson, J., Nag, A., Davies, R. W. and Shiels, P. G. (2016) Microvesicles but not exosomes from Pathfinder Cells stimulate functional recovery of the pancreas in a mouse streptozotocin-induced diabetes model. Rejuvenation Research, 19(3), pp. 223-232. (doi: 10.1089/rej.2015.1723)
McGuinness, D. and McEwan, I. J. (2016) Posttranslational modifications of steroid receptors: phosphorylation. In: McEwan, I. J. (ed.) The Nuclear Receptor Superfamily: Methods and Protocols. Series: Methods in molecular biology, 1443 (1443). Springer New York, pp. 105-117. ISBN 9781493937226 (doi: 10.1007/978-1-4939-3724-0_7)
McClelland, R. et al. (2016) Accelerated ageing and renal dysfunction links lower socioeconomic status and dietary phosphate intake. Aging, 8(5), pp. 1135-1149. (doi: 10.18632/aging.100948) (PMID:27132985) (PMCID:PMC4931858)
Bulteel, N., McGuinness, D., Shiels, P. G. and McLauchlan, J. (2016) Circulating micrornas as biomarkers for disease progression in chronic hepatitis C virus infection. EASL International Liver Congress 2016, Barcelona, Spain, 13-17 Apr 2016.
McGuinness, D. et al. (2016) Identification of molecular markers of delayed graft function based on the regulation of biological ageing. PLoS ONE, 11(1), e0146378. (doi: 10.1371/journal.pone.0146378) (PMID:26734715) (PMCID:PMC4703336)
Kato, S., Shiels, P. G. , McGuinness, D., Lindholm, B., Stenvinkel, P., Nordfors, L., Qureshi, A. R., Yuzawa, Y., Matsuo, S. and Maruyama, S. (2016) Telomere attrition and elongation after dialysis therapy initiation in patients with end-stage renal disease. Blood Purification, 41(1-3), pp. 25-33. (doi: 10.1159/000440971)
Khojah, S. M., McGuinness, D., Shiels, P. G. and Payne, A. (2016) Differential Pattern of Global DNA Methylation at Two Time Points in Brain Regions of AS/AGU Rats Compared with AS Rats. In: Eighth Saudi Students Conference in the UK, London, UK, 31 Jan - 01 Feb 2015, pp. 625-631. ISBN 9781783269143 (doi: 10.1142/9781783269150_0051)
2015
Curley, H., McGuinness, D., Kinsella, J., Quasim, T. and Shiels, P. (2015) Intensive care unit outcomes based on telomere length as a biomarker of ageing: a pilot study. British Journal of Anaesthesia, 115(6(e)), pp. 950-962. (doi: 10.1093/bja/aev116)
2014
Mcguinness, D.H. and McGuinness, D. (2014) m6a RNA methylation: the implications for health and disease. Journal of Cancer Science and Clinical Oncology, 1(1), 105. (doi: 10.15744/2394-6520.1.105)
2013
Robinson, M. W., McGuinness, D., Swann, R. , Barclay, S., Mills, P. R., Patel, A. H. , McLauchlan, J. and Shiels, P. G. (2013) Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease. Aging Cell, 12(6), pp. 1141-1143. (doi: 10.1111/acel.12125) (PMID:23931242)
Gingell-Littlejohn, M., McGuinness, D., McGlynn, L.M., Kingsmore, D., Stevenson, K.S., Koppelstaetter, C., Clancy, M.J. and Shiels, P. (2013) Pre-transplant CDKN2A expression in kidney biopsies predicts renal function and is a future component of donor scoring criteria. PLoS ONE, 8(7), e68133. (doi: 10.1371/journal.pone.0068133) (PMID:23861858) (PMCID:PMC3701657)
McGuinness, D. (2013) Fractal entropy: the return of unified theory of cancer. International Journal of Cancer Studies and Research, 2, p. 301.
Pathai, S. et al. (2013) Accelerated biological aging in HIV-infected individuals in South Africa: a case–control study. AIDS, 27(15), pp. 2375-2384. (doi: 10.1097/QAD.0b013e328363bf7f)
2012
McGuinness, D. et al. (2012) Socio-economic status is associated with epigenetic differences in the pSoBid cohort. International Journal of Epidemiology, 41(1), pp. 151-160. (doi: 10.1093/ije/dyr215)
Gingell-Littlejohn, M., McGuinness, D., Stevenson, K. S., Kingsmore, D. B., Clancy, M. and Shiels, P. G. (2012) CDKN2A Expression in Pre-Implantation Kidney Biopsies is the Single, Strongest Predictive Factor for Post-Transplant Renal Function at 1 Year. In: 15th Annual Conference of the British Transplantation Society, Glasgow, UK, 22-24 Feb 2012,
McGuinness, D., Gingell-Littlejohn, M., Stevenson, K. S., Kingsmore, D. B., Clancy, M. and Shiels, P. G. (2012) MicroRNA Regulation of Cellular Bio-age Provides a Novel Pre-Transplant Prognostic and Predictive Assessment of Post Transplant Allograft Function. In: 15th Annual Conference of the British Transplantation Society, Glasgow, UK, 22-24 Feb 2012,
2011
McGuinness, D., McGuinness, D.H. , McCaul, J. and Shiels, P.G. (2011) Sirtuins, bioageing, and cancer. Journal of Aging Research, 2011, 235754. (doi: 10.4061/2011/235754) (PMID:21766030) (PMCID:PMC3134127)
McGuinness, D., Skommer, J. and Wlodkowic, D. (2011) Self-adhesive microculture system for extended live cell imaging. Biotechnic and Histochemistry, 86(3), pp. 174-180. (doi: 10.3109/10520290903547075)
Gingell-Littlejohn, M., McGuinness, D., McGlynn, L. M., Kingsmore, D., Clancy, M. J., Koppelstaetter, C., Mayer, G. and Shiels, P.G. (2011) Telomere Length Impacts on Allograft Function Post Kidney Transplant. In: 2011 American Transplant Conference, Phildadelphia, PA, USA, 30 Apr - 4 May 2011,
2010
McEwan, I.J., McGuinness, D., Hay, C.W., Millar, R.P., Saunders, P.T. and Fraser, H.M. (2010) Identification of androgen receptor phosphorylation in the primate ovary in vivo. Reproduction, 140(1), pp. 93-104. (doi: 10.1530/REP-10-0140)
2009
Wlodkowic, D., Skommer, J., McGuinness, D., Hillier, C. and Darzynkiewicz, Z. (2009) ER-Golgi network - a future target for anti-cancer therapy. Leukemia Research, 33(11), pp. 1440-1447. (doi: 10.1016/j.leukres.2009.05.025)
Wlodkowic, D., Skommer, J., McGuinness, D., Faley, S., Kolch, W., Darzynkiewicz, Z. and Cooper, J.M. (2009) Chip-based dynamic real-time quantification of drug-induced cytotoxicity in human tumor cells. Analytical Chemistry, 81(16), pp. 6952-6959. (doi: 10.1021/ac9010217)
Wlodkowic, D., Faley, S., Skommer, J., McGuinness, D. and Cooper, J.M. (2009) Biological implications of polymeric microdevices for live cell assays. Analytical Chemistry, 81(23), pp. 9828-9833. (doi: 10.1021/ac902010s)
2008
Piestrzeniewicz-Ulanska, D., McGuinness, D.H. and Yeaman, G.R. (2008) TGF-β signaling in endometrial cancer. In: Jakowlew, S.B. (ed.) Transforming Growth Factor-β in Cancer Therapy. Series: Cancer Drug Discovery and Development, 2. Humana Press: Totowa, NJ, pp. 63-78. ISBN 9781588297150 (doi: 10.1007/978-1-59745-293-9_5)
2007
Nayyar, T., Bruner-Tran, K.L., Piestrzeniewicz-Ulanska, D. and Osteen, K.G. (2007) Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis. Reproductive Toxicology, 23(3), pp. 326-336. (doi: 10.1016/j.reprotox.2006.09.007)
2005
Bruner-Tran, K.L., McGuiness, D., Eisenberg, E. and Osteen, K.G. (2005) Endometrial Expression of TGF-Beta 2 and EBAF is Disrupted in Women with Endometriosis and in Normal Endometrium Exposed to Dioxin. In: Society for Gynecologic Investigation (SGI), Houston, TX USA, 2005, 321A. (doi: 10.1177/107155760501200205)
2004
Piestrzeniewicz-Ulanska, D., Brys, M., Semczuk, A., Rechberger, T., Jakowicki, J.A. and Krajewska, W.M. (2004) TGF-beta signaling is disrupted in endometrioid-type endometrial carcinomas. Gynecologic Oncology, 95(1), pp. 173-180. (doi: 10.1016/j.ygyno.2004.06.032)
Piestrzeniewicz-Ulanska, D., Bruner-Tran, K., Yeaman, G., Eisenberg, E. and Osteen, K. (2004) Interferon-γ induces degradation of TβR-I in the human endometrium: Implications for endometriosis. Fertility and Sterility, 82(S2), S69-S70. (doi: 10.1016/j.fertnstert.2004.07.178)
2003
Piestrzeniewicz-Ulanska, D., Brys, M., Semczuk, A., Jakowicki, J.A. and Krajewska, W.M. (2003) Expression and intracellular localization of Smad proteins in human endometrial cancer. Oncology Reports, 10(5), pp. 1539-1544.
2002
Piestrzeniewicz-Ulanska, D., Brys, M., Semczuk, A., Jakowicki, J.A. and Krajewska, W.M. (2002) Expression of TGF-beta type I and II receptors in normal and cancerous human endometrium. Cancer Letters, 186(2), pp. 231-239. (doi: 10.1016/S0304-3835(02)00351-8)
2001
Piestrzeniewicz-Ulanska, D. and Krajewska, W.M. (2001) Crossing path with smads. In: Heilmeyer, L. and Friedrisch, P. (eds.) Protein Modules in Cellular Signalling. Series: NATO science series. Series A, Life sciences,; v. 318; Variation: NATO science series.; Series A,; Life sciences ;; v. 318., 318. IOS Press,US: USA, pp. 123-131. ISBN 9781586031800
2000
Piestrzeniewicz-Ulanska, D., Brys, M. and Krajewska, W.M. (2000) The smad pathway in TGF-β signalling. Cellular and Molecular Biology Letters, 5, pp. 381-396.
1999
Blasiak, J., Smolarz, B. and Piestrzeniewicz, D. (1999) Urokinazowy układ aktywacji plazminogenu i jego znaczenie w progresji nowotworów. Postepy Biochemii, 45, pp. 42-50.
1998
Blasiak, J., Smolarz, B. and Piestrzeniewicz, D. (1998) Urokinase plasminogen activator system and its role in cancer and metastasis. Acta Universitatis Lodziensis: Folia Biochimica et Biophysica, 14, pp. 175-190.
Blasiak, J., Smolarz, B., Piestrzeniewicz, D. and Pytel, J. (1998) The 4G/5G polymorphism in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene in subject with cancer. Acta Universitatis Lodziensis: Folia Biochimica et Biophysica, 14, pp. 167-174.
Smolarz, B., Blasiak, J., Piestrzeniewicz, D. and Pytel, J. (1998) Plasminogen activator inhibitor-1 (PAI-1) gene 4G/5G promoter polymorphism in subjects with cancer. Cellular and Molecular Biology Letters, 3(1), pp. 49-56.
Articles
Nyirenda, J. et al. (2024) Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population. Nature Medicine, (doi: 10.1038/s41591-024-03354-3) (Early Online Publication)
Abrams, S. T. et al. (2024) Damage-associated cellular markers in the clinical and pathogenic profile of vaccine-induced immune thrombotic thrombocytopenia. Journal of Thrombosis and Haemostasis, 22(4), pp. 1145-1153. (doi: 10.1016/j.jtha.2023.12.008) (PMID:38103733)
Nyirenda, J. et al. (2023) Spatially resolved single-cell atlas of the lung in fatal Covid19 in an African population reveals a distinct cellular signature and an interferon gamma dominated response. bioRxiv, (doi: 10.1101/2023.11.16.566964)
Craven, H., Erlandsson, H., McGuinness, D., McGuinness, D. , Mafra, D., Ijaz, U. Z. , Bergman, P., Shiels, P. G. and Stenvinkel, P. (2023) A normative microbiome is not restored following kidney transplantation. Clinical Science, 137(20), pp. 1563-1575. (doi: 10.1042/CS20230779) (PMID:37756543)
Panagiotou, N. , McGuinness, D., Jaminon, A. M.G., Mees, B., Selman, C. , Schurgers, L. and Shiels, P. G. (2023) Microvesicle-mediated tissue regeneration mitigates the effects of cellular ageing. Cells, 12(13), 1707. (doi: 10.3390/cells12131707) (PMID:37443741) (PMCID:PMC10340655)
Mulvey, L., Wilkie, S. E., Borland, G., Griffiths, K., Sinclair, A., McGuinness, D., Watson, D. G. and Selman, C. (2021) Strain-specific metabolic responses to long-term caloric restriction in female ILSXISS recombinant inbred mice. Molecular and Cellular Endocrinology, 535, 111376. (doi: 10.1016/j.mce.2021.111376) (PMID:34246728) (PMCID:PMC8417819)
Craven, H. et al. (2021) Socioeconomic position links circulatory microbiota differences with biological age. Scientific Reports, 11, 12629. (doi: 10.1038/s41598-021-92042-0) (PMID:34135381) (PMCID:PMC8209159)
Moxon, C. A. et al. (2020) Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria. Blood Advances, 4(13), pp. 2851-2864. (doi: 10.1182/bloodadvances.2019001258) (PMID:32579667) (PMCID:PMC7362376)
Moxon, C. A. , Gibbins, M. P. , McGuinness, D., Milner, D. A. and Marti, M. (2020) New insights into malaria pathogenesis. Annual Review of Pathology: Mechanisms of Disease, 15(1), pp. 315-343. (doi: 10.1146/annurev-pathmechdis-012419-032640) (PMID:31648610)
de Kok, M. J. et al. (2019) The neglectable impact of delayed graft function on long-term graft survival in kidneys donated after circulatory death associates with superior organ resilience. Annals of Surgery, 270(5), pp. 877-883. (doi: 10.1097/SLA.0000000000003515) (PMID:31567503)
Diaz-Albiter, H. M., Regnault, C., Alpizar-Sosa, E. A., McGuinness, D., Barrett, M. P. and Dillon, R. J. (2018) Non-invasive visualisation and identification of fluorescent. Wellcome Open Research, 3, 160. (doi: 10.12688/wellcomeopenres.14910.1) (PMID:30756095) (PMCID:PMC6367660)
McGuinness, D. et al. (2018) A molecular signature for delayed graft function. Aging Cell, 17(5), e12825. (doi: 10.1111/acel.12825) (PMID:30094915) (PMCID:PMC6156499)
Lakhdar, R., McGuinness, D., Drost, E. M., Shiels, P. G. , Bastos, R., MacNee, W. and Rabinovich, R. A. (2018) Role of accelerated ageing in limb muscle wasting of patients with COPD. International Journal of Chronic Obstructive Pulmonary Disease, 13, pp. 1987-1998. (doi: 10.2147/COPD.S155952) (PMID:29970961) (PMCID:PMC6022820)
Shiels, P. G. , McGuinness, D., Eriksson, M., Kooman, J. P. and Stenvinkel, P. (2017) The role of epigenetics in renal ageing. Nature Reviews Nephrology, 13, pp. 471-482. (doi: 10.1038/nrneph.2017.78) (PMID:28626222)
Shiels, P. G. , Stenvinkel, P., Kooman, J. P. and McGuinness, D. (2017) Circulating markers of ageing and allostatic load: a slow train coming. Practical Laboratory Medicine, 7, pp. 49-54. (doi: 10.1016/j.plabm.2016.04.002) (PMID:28856219) (PMCID:PMC5574864)
Stenvinkel, P. et al. (2017) CDKN2A/p16INK4a expression is associated with vascular progeria in chronic kidney disease. Aging, 9(2), pp. 494-507. (doi: 10.18632/aging.101173) (PMID:28192277)
Khojah, S. M., Payne, A. P., McGuinness, D. and Shields, P. G. (2016) Segmental aging underlies the development of a Parkinson phenotype in the AS/AGU rat. Cells, 5(4), 38. (doi: 10.3390/cells5040038) (PMID:27763519) (PMCID:PMC5187522)
Luttropp, K. et al. (2016) Increased telomere attrition following renal transplantation: impact of anti-metabolite therapy. Transplantation Direct, 2(12), e116. (doi: 10.1097/TXD.0000000000000629) (PMID:27990481) (PMCID:PMC5142370)
McGuinness, D., Anthony, D. F., Moulisova, V. , MacDonald, A. I., Macintyre, A., Thomson, J., Nag, A., Davies, R. W. and Shiels, P. G. (2016) Microvesicles but not exosomes from Pathfinder Cells stimulate functional recovery of the pancreas in a mouse streptozotocin-induced diabetes model. Rejuvenation Research, 19(3), pp. 223-232. (doi: 10.1089/rej.2015.1723)
McClelland, R. et al. (2016) Accelerated ageing and renal dysfunction links lower socioeconomic status and dietary phosphate intake. Aging, 8(5), pp. 1135-1149. (doi: 10.18632/aging.100948) (PMID:27132985) (PMCID:PMC4931858)
McGuinness, D. et al. (2016) Identification of molecular markers of delayed graft function based on the regulation of biological ageing. PLoS ONE, 11(1), e0146378. (doi: 10.1371/journal.pone.0146378) (PMID:26734715) (PMCID:PMC4703336)
Kato, S., Shiels, P. G. , McGuinness, D., Lindholm, B., Stenvinkel, P., Nordfors, L., Qureshi, A. R., Yuzawa, Y., Matsuo, S. and Maruyama, S. (2016) Telomere attrition and elongation after dialysis therapy initiation in patients with end-stage renal disease. Blood Purification, 41(1-3), pp. 25-33. (doi: 10.1159/000440971)
Curley, H., McGuinness, D., Kinsella, J., Quasim, T. and Shiels, P. (2015) Intensive care unit outcomes based on telomere length as a biomarker of ageing: a pilot study. British Journal of Anaesthesia, 115(6(e)), pp. 950-962. (doi: 10.1093/bja/aev116)
Mcguinness, D.H. and McGuinness, D. (2014) m6a RNA methylation: the implications for health and disease. Journal of Cancer Science and Clinical Oncology, 1(1), 105. (doi: 10.15744/2394-6520.1.105)
Robinson, M. W., McGuinness, D., Swann, R. , Barclay, S., Mills, P. R., Patel, A. H. , McLauchlan, J. and Shiels, P. G. (2013) Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease. Aging Cell, 12(6), pp. 1141-1143. (doi: 10.1111/acel.12125) (PMID:23931242)
Gingell-Littlejohn, M., McGuinness, D., McGlynn, L.M., Kingsmore, D., Stevenson, K.S., Koppelstaetter, C., Clancy, M.J. and Shiels, P. (2013) Pre-transplant CDKN2A expression in kidney biopsies predicts renal function and is a future component of donor scoring criteria. PLoS ONE, 8(7), e68133. (doi: 10.1371/journal.pone.0068133) (PMID:23861858) (PMCID:PMC3701657)
McGuinness, D. (2013) Fractal entropy: the return of unified theory of cancer. International Journal of Cancer Studies and Research, 2, p. 301.
Pathai, S. et al. (2013) Accelerated biological aging in HIV-infected individuals in South Africa: a case–control study. AIDS, 27(15), pp. 2375-2384. (doi: 10.1097/QAD.0b013e328363bf7f)
McGuinness, D. et al. (2012) Socio-economic status is associated with epigenetic differences in the pSoBid cohort. International Journal of Epidemiology, 41(1), pp. 151-160. (doi: 10.1093/ije/dyr215)
McGuinness, D., McGuinness, D.H. , McCaul, J. and Shiels, P.G. (2011) Sirtuins, bioageing, and cancer. Journal of Aging Research, 2011, 235754. (doi: 10.4061/2011/235754) (PMID:21766030) (PMCID:PMC3134127)
McGuinness, D., Skommer, J. and Wlodkowic, D. (2011) Self-adhesive microculture system for extended live cell imaging. Biotechnic and Histochemistry, 86(3), pp. 174-180. (doi: 10.3109/10520290903547075)
McEwan, I.J., McGuinness, D., Hay, C.W., Millar, R.P., Saunders, P.T. and Fraser, H.M. (2010) Identification of androgen receptor phosphorylation in the primate ovary in vivo. Reproduction, 140(1), pp. 93-104. (doi: 10.1530/REP-10-0140)
Wlodkowic, D., Skommer, J., McGuinness, D., Hillier, C. and Darzynkiewicz, Z. (2009) ER-Golgi network - a future target for anti-cancer therapy. Leukemia Research, 33(11), pp. 1440-1447. (doi: 10.1016/j.leukres.2009.05.025)
Wlodkowic, D., Skommer, J., McGuinness, D., Faley, S., Kolch, W., Darzynkiewicz, Z. and Cooper, J.M. (2009) Chip-based dynamic real-time quantification of drug-induced cytotoxicity in human tumor cells. Analytical Chemistry, 81(16), pp. 6952-6959. (doi: 10.1021/ac9010217)
Wlodkowic, D., Faley, S., Skommer, J., McGuinness, D. and Cooper, J.M. (2009) Biological implications of polymeric microdevices for live cell assays. Analytical Chemistry, 81(23), pp. 9828-9833. (doi: 10.1021/ac902010s)
Nayyar, T., Bruner-Tran, K.L., Piestrzeniewicz-Ulanska, D. and Osteen, K.G. (2007) Developmental exposure of mice to TCDD elicits a similar uterine phenotype in adult animals as observed in women with endometriosis. Reproductive Toxicology, 23(3), pp. 326-336. (doi: 10.1016/j.reprotox.2006.09.007)
Piestrzeniewicz-Ulanska, D., Brys, M., Semczuk, A., Rechberger, T., Jakowicki, J.A. and Krajewska, W.M. (2004) TGF-beta signaling is disrupted in endometrioid-type endometrial carcinomas. Gynecologic Oncology, 95(1), pp. 173-180. (doi: 10.1016/j.ygyno.2004.06.032)
Piestrzeniewicz-Ulanska, D., Bruner-Tran, K., Yeaman, G., Eisenberg, E. and Osteen, K. (2004) Interferon-γ induces degradation of TβR-I in the human endometrium: Implications for endometriosis. Fertility and Sterility, 82(S2), S69-S70. (doi: 10.1016/j.fertnstert.2004.07.178)
Piestrzeniewicz-Ulanska, D., Brys, M., Semczuk, A., Jakowicki, J.A. and Krajewska, W.M. (2003) Expression and intracellular localization of Smad proteins in human endometrial cancer. Oncology Reports, 10(5), pp. 1539-1544.
Piestrzeniewicz-Ulanska, D., Brys, M., Semczuk, A., Jakowicki, J.A. and Krajewska, W.M. (2002) Expression of TGF-beta type I and II receptors in normal and cancerous human endometrium. Cancer Letters, 186(2), pp. 231-239. (doi: 10.1016/S0304-3835(02)00351-8)
Piestrzeniewicz-Ulanska, D., Brys, M. and Krajewska, W.M. (2000) The smad pathway in TGF-β signalling. Cellular and Molecular Biology Letters, 5, pp. 381-396.
Blasiak, J., Smolarz, B. and Piestrzeniewicz, D. (1999) Urokinazowy układ aktywacji plazminogenu i jego znaczenie w progresji nowotworów. Postepy Biochemii, 45, pp. 42-50.
Blasiak, J., Smolarz, B. and Piestrzeniewicz, D. (1998) Urokinase plasminogen activator system and its role in cancer and metastasis. Acta Universitatis Lodziensis: Folia Biochimica et Biophysica, 14, pp. 175-190.
Blasiak, J., Smolarz, B., Piestrzeniewicz, D. and Pytel, J. (1998) The 4G/5G polymorphism in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene in subject with cancer. Acta Universitatis Lodziensis: Folia Biochimica et Biophysica, 14, pp. 167-174.
Smolarz, B., Blasiak, J., Piestrzeniewicz, D. and Pytel, J. (1998) Plasminogen activator inhibitor-1 (PAI-1) gene 4G/5G promoter polymorphism in subjects with cancer. Cellular and Molecular Biology Letters, 3(1), pp. 49-56.
Book Sections
McGuinness, D. and McEwan, I. J. (2016) Posttranslational modifications of steroid receptors: phosphorylation. In: McEwan, I. J. (ed.) The Nuclear Receptor Superfamily: Methods and Protocols. Series: Methods in molecular biology, 1443 (1443). Springer New York, pp. 105-117. ISBN 9781493937226 (doi: 10.1007/978-1-4939-3724-0_7)
Piestrzeniewicz-Ulanska, D., McGuinness, D.H. and Yeaman, G.R. (2008) TGF-β signaling in endometrial cancer. In: Jakowlew, S.B. (ed.) Transforming Growth Factor-β in Cancer Therapy. Series: Cancer Drug Discovery and Development, 2. Humana Press: Totowa, NJ, pp. 63-78. ISBN 9781588297150 (doi: 10.1007/978-1-59745-293-9_5)
Piestrzeniewicz-Ulanska, D. and Krajewska, W.M. (2001) Crossing path with smads. In: Heilmeyer, L. and Friedrisch, P. (eds.) Protein Modules in Cellular Signalling. Series: NATO science series. Series A, Life sciences,; v. 318; Variation: NATO science series.; Series A,; Life sciences ;; v. 318., 318. IOS Press,US: USA, pp. 123-131. ISBN 9781586031800
Conference or Workshop Item
Bulteel, N., McGuinness, D., Shiels, P. G. and McLauchlan, J. (2016) Circulating micrornas as biomarkers for disease progression in chronic hepatitis C virus infection. EASL International Liver Congress 2016, Barcelona, Spain, 13-17 Apr 2016.
Conference Proceedings
Khojah, S. M., McGuinness, D., Shiels, P. G. and Payne, A. (2016) Differential Pattern of Global DNA Methylation at Two Time Points in Brain Regions of AS/AGU Rats Compared with AS Rats. In: Eighth Saudi Students Conference in the UK, London, UK, 31 Jan - 01 Feb 2015, pp. 625-631. ISBN 9781783269143 (doi: 10.1142/9781783269150_0051)
Gingell-Littlejohn, M., McGuinness, D., Stevenson, K. S., Kingsmore, D. B., Clancy, M. and Shiels, P. G. (2012) CDKN2A Expression in Pre-Implantation Kidney Biopsies is the Single, Strongest Predictive Factor for Post-Transplant Renal Function at 1 Year. In: 15th Annual Conference of the British Transplantation Society, Glasgow, UK, 22-24 Feb 2012,
McGuinness, D., Gingell-Littlejohn, M., Stevenson, K. S., Kingsmore, D. B., Clancy, M. and Shiels, P. G. (2012) MicroRNA Regulation of Cellular Bio-age Provides a Novel Pre-Transplant Prognostic and Predictive Assessment of Post Transplant Allograft Function. In: 15th Annual Conference of the British Transplantation Society, Glasgow, UK, 22-24 Feb 2012,
Gingell-Littlejohn, M., McGuinness, D., McGlynn, L. M., Kingsmore, D., Clancy, M. J., Koppelstaetter, C., Mayer, G. and Shiels, P.G. (2011) Telomere Length Impacts on Allograft Function Post Kidney Transplant. In: 2011 American Transplant Conference, Phildadelphia, PA, USA, 30 Apr - 4 May 2011,
Bruner-Tran, K.L., McGuiness, D., Eisenberg, E. and Osteen, K.G. (2005) Endometrial Expression of TGF-Beta 2 and EBAF is Disrupted in Women with Endometriosis and in Normal Endometrium Exposed to Dioxin. In: Society for Gynecologic Investigation (SGI), Houston, TX USA, 2005, 321A. (doi: 10.1177/107155760501200205)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Sepsis treatment by targeting antibiotic released bacterial proteins (STTAR-BacPro)
Medical Research Council
2024 - 2024