Dr Amit Meir Ben Efraim
- Research Associate (Virology)
email:
Amit.Meir@glasgow.ac.uk
pronouns:
She/her/hers
https://orcid.org/0000-0001-9635-1021Publications
2024
Malmsheimer, S. et al. (2024) The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors. PLoS Pathogens, 20(11), e1012118. (doi: 10.1371/journal.ppat.1012118) (PMID:39546547) (PMCID:PMC11602083)
2023
Meir, A. , Macé, K., Vegunta, Y., Williams, S. M. and Waksman, G. (2023) Substrate recruitment mechanism by gram-negative type III, IV, and VI bacterial injectisomes. Trends in Microbiology, 31(9), pp. 916-932. (doi: 10.1016/j.tim.2023.03.005) (PMID:37085348)
2022
Macé, K., Meir, A. , Lukoyanova, N., Liu, L., Chetrit, D., Hospenthal, M. K., Roy, C. R. and Waksman, G. (2022) Proteins DotY and DotZ modulate the dynamics and localization of the type IVB coupling complex of Legionella pneumophila. Molecular Microbiology, 117(2), pp. 307-319. (doi: 10.1111/mmi.14847) (PMID:34816517) (PMCID:PMC9300119)
2021
Steiner, S., Meir, A. and Roy, C. R. (2021) Coxiella burnetii encodes an LvgA-related protein important for intracellular replication. Cellular Microbiology, 23(6), e13331. (doi: 10.1111/cmi.13331) (PMID:33774901)
2020
Takahashi, T. et al. (2020) Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature, 588(7837), pp. 315-320. (doi: 10.1038/s41586-020-2700-3) (PMID:32846427) (PMCID:PMC7725931)
Israelow, B. et al. (2020) Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling. Journal of Experimental Medicine, 217(12), e20201241. (doi: 10.1084/jem.20201241) (PMID:32750141) (PMCID:PMC7401025)
Liu, F. et al. (2020) Newborn dried blood spots for serologic surveys of COVID-19. Pediatric Infectious Disease Journal, 39(12), e454-e456. (doi: 10.1097/INF.0000000000002918) (PMID:33105339) (PMCID:PMC7654948)
Meir, A. , Macé, K., Lukoyanova, N., Chetrit, D., Hospenthal, M. K., Redzej, A., Roy, C. and Waksman, G. (2020) Mechanism of effector capture and delivery by the type IV secretion system from Legionella pneumophila. Nature Communications, 11, 2864. (doi: 10.1038/s41467-020-16681-z) (PMID:32513920) (PMCID:PMC7280309)
2018
Meir, A. , Chetrit, D., Liu, L., Roy, C. R. and Waksman, G. (2018) Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system. Nature Communications, 9, 507. (doi: 10.1038/s41467-017-02578-x) (PMID:29410427) (PMCID:PMC5802825)
2015
Avraham, O., Meir, A. , Fish, A., Bayer, E. A. and Livnah, O. (2015) Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail. Journal of Structural Biology, 191(2), pp. 139-148. (doi: 10.1016/j.jsb.2015.06.020) (PMID:26126731)
Costa, T. R. D., Felisberto-Rodrigues, C., Meir, A. , Prevost, M. S., Redzej, A., Trokter, M. and Waksman, G. (2015) Secretion systems in Gram-negative bacteria: structural and mechanistic insights. Nature Reviews Microbiology, 13(6), pp. 343-359. (doi: 10.1038/nrmicro3456) (PMID:25978706)
2013
Leppiniemi, J., Meir, A. , Kähkönen, N., Kukkurainen, S., Määttä, J. A., Ojanen, M., Jänis, J., Kulomaa, M. S., Livnah, O. and Hytönen, V. P. (2013) The highly dynamic oligomeric structure of bradavidin II is unique among avidin proteins: Bradavidin II: Highly Dynamic Oligomeric State. Protein Science, 22(7), pp. 980-994. (doi: 10.1002/pro.2281)
2012
Meir, A. , Bayer, E. A. and Livnah, O. (2012) Structural adaptation of a thermostable biotin-binding protein in a psychrophilic environment. Journal of Biological Chemistry, 287(22), pp. 17951-17962. (doi: 10.1074/jbc.M112.357186) (PMID:22493427) (PMCID:PMC3365750)
2010
Meir., A. and Livnah, O. (2010) Challenging semi-bootstrapping molecular-replacement strategy reveals intriguing crystal packing of rhizavidin. Acta Crystallographica Section F: Structural Biology Communications, F66, pp. 373-378. (doi: 10.1107/s1744309110004112) (PMID:20383003) (PMCID:PMC2852325)
2009
Meir, A. , Helppolainen, S. H., Podoly, E., Nordlund, H. R., Hytönen, V. P., Määttä, J. A., Wilchek, M., Bayer, E. A., Kulomaa, M. S. and Livnah, O. (2009) Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer. Journal of Molecular Biology, 386(2), pp. 379-390. (doi: 10.1016/j.jmb.2008.11.061) (PMID:19111749)
Articles
Malmsheimer, S. et al. (2024) The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors. PLoS Pathogens, 20(11), e1012118. (doi: 10.1371/journal.ppat.1012118) (PMID:39546547) (PMCID:PMC11602083)
Meir, A. , Macé, K., Vegunta, Y., Williams, S. M. and Waksman, G. (2023) Substrate recruitment mechanism by gram-negative type III, IV, and VI bacterial injectisomes. Trends in Microbiology, 31(9), pp. 916-932. (doi: 10.1016/j.tim.2023.03.005) (PMID:37085348)
Macé, K., Meir, A. , Lukoyanova, N., Liu, L., Chetrit, D., Hospenthal, M. K., Roy, C. R. and Waksman, G. (2022) Proteins DotY and DotZ modulate the dynamics and localization of the type IVB coupling complex of Legionella pneumophila. Molecular Microbiology, 117(2), pp. 307-319. (doi: 10.1111/mmi.14847) (PMID:34816517) (PMCID:PMC9300119)
Steiner, S., Meir, A. and Roy, C. R. (2021) Coxiella burnetii encodes an LvgA-related protein important for intracellular replication. Cellular Microbiology, 23(6), e13331. (doi: 10.1111/cmi.13331) (PMID:33774901)
Takahashi, T. et al. (2020) Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature, 588(7837), pp. 315-320. (doi: 10.1038/s41586-020-2700-3) (PMID:32846427) (PMCID:PMC7725931)
Israelow, B. et al. (2020) Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling. Journal of Experimental Medicine, 217(12), e20201241. (doi: 10.1084/jem.20201241) (PMID:32750141) (PMCID:PMC7401025)
Liu, F. et al. (2020) Newborn dried blood spots for serologic surveys of COVID-19. Pediatric Infectious Disease Journal, 39(12), e454-e456. (doi: 10.1097/INF.0000000000002918) (PMID:33105339) (PMCID:PMC7654948)
Meir, A. , Macé, K., Lukoyanova, N., Chetrit, D., Hospenthal, M. K., Redzej, A., Roy, C. and Waksman, G. (2020) Mechanism of effector capture and delivery by the type IV secretion system from Legionella pneumophila. Nature Communications, 11, 2864. (doi: 10.1038/s41467-020-16681-z) (PMID:32513920) (PMCID:PMC7280309)
Meir, A. , Chetrit, D., Liu, L., Roy, C. R. and Waksman, G. (2018) Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system. Nature Communications, 9, 507. (doi: 10.1038/s41467-017-02578-x) (PMID:29410427) (PMCID:PMC5802825)
Avraham, O., Meir, A. , Fish, A., Bayer, E. A. and Livnah, O. (2015) Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail. Journal of Structural Biology, 191(2), pp. 139-148. (doi: 10.1016/j.jsb.2015.06.020) (PMID:26126731)
Costa, T. R. D., Felisberto-Rodrigues, C., Meir, A. , Prevost, M. S., Redzej, A., Trokter, M. and Waksman, G. (2015) Secretion systems in Gram-negative bacteria: structural and mechanistic insights. Nature Reviews Microbiology, 13(6), pp. 343-359. (doi: 10.1038/nrmicro3456) (PMID:25978706)
Leppiniemi, J., Meir, A. , Kähkönen, N., Kukkurainen, S., Määttä, J. A., Ojanen, M., Jänis, J., Kulomaa, M. S., Livnah, O. and Hytönen, V. P. (2013) The highly dynamic oligomeric structure of bradavidin II is unique among avidin proteins: Bradavidin II: Highly Dynamic Oligomeric State. Protein Science, 22(7), pp. 980-994. (doi: 10.1002/pro.2281)
Meir, A. , Bayer, E. A. and Livnah, O. (2012) Structural adaptation of a thermostable biotin-binding protein in a psychrophilic environment. Journal of Biological Chemistry, 287(22), pp. 17951-17962. (doi: 10.1074/jbc.M112.357186) (PMID:22493427) (PMCID:PMC3365750)
Meir., A. and Livnah, O. (2010) Challenging semi-bootstrapping molecular-replacement strategy reveals intriguing crystal packing of rhizavidin. Acta Crystallographica Section F: Structural Biology Communications, F66, pp. 373-378. (doi: 10.1107/s1744309110004112) (PMID:20383003) (PMCID:PMC2852325)
Meir, A. , Helppolainen, S. H., Podoly, E., Nordlund, H. R., Hytönen, V. P., Määttä, J. A., Wilchek, M., Bayer, E. A., Kulomaa, M. S. and Livnah, O. (2009) Crystal structure of rhizavidin: insights into the enigmatic high-affinity interaction of an innate biotin-binding protein dimer. Journal of Molecular Biology, 386(2), pp. 379-390. (doi: 10.1016/j.jmb.2008.11.061) (PMID:19111749)