Dr Kevin Wing
- Senior Lecturer in Pharmacoepidemiology (Public Health)
email:
Kevin.Wing@glasgow.ac.uk
School of Health & Wellbeing, Clarice Pears Building, 90 Byres Road, Glasgow, G12 8TB
Biography
I am an epidemiologist with experience of the design and analysis of observational studies across a variety of settings and disease areas. My recent work focuses on the use of routinely collected health data to generate evidence of drug treatment effects in people underrepresented in or excluded from randomised controlled trials.
I also have experience of leading, designing and delivering MSc and short course teaching related to both epidemiology and pharmacoepidemiology.
Research interests
- Use of RCTs to improve the validity of observational analysis in big data
- Drug utilisation (interrupted time series) studies
- Standards for pharmacoepidemiology
- Respiratory disease
- Cardiovascular disease
- Diabetes
- Epilepsy
- Post-acute infection syndromes
- ME/CFS
Publications
Prior publications
ORCiD
Paris J Baptiste, Angel Y S Wong, Anna Schultze, Catherine M Clase, Clémence Leyrat, Elizabeth Williamson, Emma Powell, Johannes F E Mann, Marianne Cunnington, Koon Teo, Shrikant I Bangdiwala, Peggy Gao, Kevin Wing, Laurie Tomlinson, (2024) Cardiorenal effects of dual blockade with Angiotensin-converting enzyme inhibitors and Angiotensin receptor blockers in people with CKD: analysis of routinely collected data with emulation of a reference trial (ONTARGET) (doi: 10.1101/2024.05.28.24307859)(source-work-id: 225666); source: London School of Hygiene and Tropical Medicine
Jeremy P Brown, Jacob N Hunnicutt, M Sanni Ali, Krishnan Bhaskaran, Ashley Cole, Sinead Langan, Dorothea Nitsch, Christopher T. Rentsch, Nicholas W Galwey, Kevin Wing, Ian Douglas, (2024) Quantifying possible bias in clinical and epidemiological studies with quantitative bias analysis: common approaches and limitations. The BMJ (pmid: 38565248)(doi: 10.1136/bmj-2023-076365)(issn: 0959-8138)(source-work-id: 217868); source: London School of Hygiene and Tropical Medicine
Jeremy P Brown, Kevin Wing, Clémence Leyrat, Stephen Evans, Kathryn Mansfield, Angel Yun Sum Wong, Liam Smeeth, Nicholas W Galwey, Ian Douglas, (2023) Association Between Fluoroquinolone Use and Hospitalization With Aortic Aneurysm or Aortic Dissection. JAMA cardiology (pmc: PMC10433140)(pmid: 37585175)(doi: 10.1001/jamacardio.2023.2418)(issn: 2380-6583)(source-work-id: 207831); source: London School of Hygiene and Tropical Medicine
Shahab Abtahi, Romin Pajouheshnia, Carlos E Durán, Judit Riera-Arnau, Magdalena Gamba, Ema Alsina, Vjola Hoxhaj, Morten Andersen, Claudia Bartolini, Sarah Brøgger Kristiansen, Jeremy Brown, Christine Erikstrup Hallgreen, Patricia Garcia-Poza, Helga Gardarsdottir, Rosa Gini, Anna Girardi, Emily Holthuis, Consuelo Huerta, Luisa Ibánez, Giorgio Limoncella, Mar Martín-Pérez, Olga Paoletti, Giuseppe Roberto, Patrick Souverein, Karin M A Swart, Kevin Wing, Miriam Sturkenboom, Olaf Klungel, (2023) Impact of 2018 EU Risk Minimisation Measures and Revised Pregnancy Prevention Programme on Utilisation and Prescribing Trends of Medicinal Products Containing Valproate: An Interrupted Time Series Study. Drug Safety (pmc: PMC10252161)(pmid: 37294532)(doi: 10.1007/s40264-023-01314-3)(issn: 0114-5916)(source-work-id: 205211); source: London School of Hygiene and Tropical Medicine
Hannah R Whittaker, Kevin Wing, Ian Douglas, Steven J Kiddle, Jennifer K Quint, (2022) Inhaled Corticosteroid Withdrawal and Change in Lung Function in Primary Care Patients with Chronic Obstructive Pulmonary Disease in England. Annals of the American Thoracic Society (pmid: 35767034)(doi: 10.1513/annalsats.202111-1238oc)(issn: 2329-6933)(source-work-id: 181172); source: London School of Hygiene and Tropical Medicine
Kevin Wing, Daniel Grint, Rohini Mathur, Hamish P Gibbs, George Hickman, Emily Nightingale, Anna Schultze, Harriet Forbes, Vahé Nafilyan, Krishnan Bhaskaran, Elizabeth Williamson, Thomas House, Lorenzo Pellis, Emily Herrett, Nileesa Gautam, Helen J Curtis, Christopher T. Rentsch, Angel Yun Sum Wong, Brian MacKenna, Amir Mehrkar, Seb Bacon, Ian Douglas, Stephen Evans, Laurie Tomlinson, Ben Goldacre, Rosalind M Eggo, (2022) Association between household composition and severe COVID-19 outcomes in older people by ethnicity: an observational cohort study using the OpenSAFELY platform. International Journal of Epidemiology (pmc: PMC9384728)(pmid: 35962974)(doi: 10.1093/ije/dyac158)(issn: 0300-5771)(wosuid: WOS:000840131300001)(source-work-id: 182046); source: London School of Hygiene and Tropical Medicine
Florence Brellier, Mar Pujades-Rodriguez, Emma Powell, Kathleen Mudie, Eliana Lacerda, Luis Nacul, Kevin Wing, (2022) Incidence of Lyme disease in the United Kingdom and association with fatigue: A population-based, historical cohort study. PLoS ONE (pmc: PMC8942220)(pmid: 35320297)(doi: 10.1371/journal.pone.0265765)(issn: 1932-6203)(wosuid: WOS:000784240600029)(source-work-id: 175517); source: London School of Hygiene and Tropical Medicine
Krishnan Bhaskaran, Christopher T. Rentsch, George Hickman, William J Hulme, Anna Schultze, Helen J Curtis, Kevin Wing, Charlotte Warren-Gash, Laurie Tomlinson, Chris J Bates, Rohini Mathur, Brian MacKenna, Viyaasan Mahalingasivam, Angel Yun Sum Wong, Alex J Walker, Caroline E Morton, Daniel Grint, Amir Mehrkar, Rosalind M Eggo, Peter Inglesby, Ian Douglas, Helen McDonald, Jonathan Cockburn, Elizabeth Williamson, David Evans, John Parry, Frank Hester, Sam Harper, Stephen Evans, Sebastian Bacon, Liam Smeeth, Ben Goldacre, (2022) Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform. PLoS Medicine (pmc: PMC8789178)(pmid: 35077449)(doi: 10.1371/journal.pmed.1003871)(issn: 1549-1277)(source-work-id: 169899); source: London School of Hygiene and Tropical Medicine
Anna J Hussey, Kevin Wing, Madonna Ferrone, Christopher J Licskai, (2021) Integrated Disease Management for Chronic Obstructive Pulmonary Disease in Primary Care, from the Controlled Trial to Clinical Program: A Cohort Study. International Journal of COPD (pmid: 35221683)(pmc: PMC8866979)(doi: 10.2147/COPD.S338851)(issn: 1178-2005)(wosuid: WOS:000735179500001)(source-work-id: 171660); source: London School of Hygiene and Tropical Medicine
Sharon Cadogan, Emma Powell, Kevin Wing, Angel Yun Sum Wong, Liam Smeeth, Charlotte Warren-Gash, (2021) Anticoagulant prescribing for atrial fibrillation and risk of incident dementia. Heart (pmc: PMC8600601)(pmid: 34645643)(doi: 10.1136/heartjnl-2021-319672)(issn: 1355-6037)(wosuid: WOS:000720478900013)(source-work-id: 166626); source: London School of Hygiene and Tropical Medicine
Daniel Grint, Kevin Wing, Catherine Houlihan, Hamish P Gibbs, Stephen Evans, Elizabeth Williamson, Helen McDonald, Krishnan Bhaskaran, David Evans, Alex J Walker, George Hickman, Emily Nightingale, Anna Schultze, Christopher T. Rentsch, Chris Bates, Jonathan Cockburn, Helen J Curtis, Caroline E Morton, Sebastian Bacon, Simon Davy, Angel Yun Sum Wong, Amir Mehrkar, Laurie Tomlinson, Ian Douglas, Rohini Mathur, Brian MacKenna, Peter Ingelsby, Richard Croker, John Parry, Frank Hester, Sam Harper, Nicholas J DeVito, Will Hulme, John Tazare, Liam Smeeth, Ben Goldacre, Rosalind M Eggo, (2021) Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England. Clinical Infectious Diseases (pmc: PMC8522415)(pmid: 34487522)(doi: 10.1093/cid/ciab754)(issn: 1058-4838)(wosuid: WOS:000756444900001)(source-work-id: 165946); source: London School of Hygiene and Tropical Medicine
Hannah Whittaker, Steven Kiddle, Ian Douglas, Kevin Wing, Jennifer Quint, (2021) ICS withdrawal and rate of FEV1 decline in a primary care COPD population in England European Respiratory Journal (doi: 10.1183/13993003.congress-2021.OA2865)(issn: 0903-1936)(wosuid: WOS:000747452100384)(source-work-id: 171659); source: London School of Hygiene and Tropical Medicine
Kevin Wing, Elizabeth Williamson, James Carpenter, Lesley Wise, Sebastian Schneeweiss, Liam Smeeth, Jennifer K Quint, Ian Douglas, (2021) Medications for chronic obstructive pulmonary disease: a historical non-interventional cohort study with validation against RCT results. Health Technology Assessment (pmid: 34463610)(doi: 10.3310/hta25510)(issn: 1366-5278)(wosuid: WOS:000689121000001)(source-work-id: 165920); source: London School of Hygiene and Tropical Medicine
Emma Powell, Ian Douglas, Usha Gungabissoon, Liam Smeeth, Kevin Wing, (2021) Real-world effects of medications for stroke prevention in atrial fibrillation: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results. BMJ Open (pmc: PMC8055153)(pmid: 33858866)(doi: 10.1136/bmjopen-2020-042947)(issn: 2044-6055)(wosuid: WOS:000641716000001)(source-work-id: 159228); source: London School of Hygiene and Tropical Medicine
Daniel Grint, Kevin Wing, Elizabeth Williamson, Helen McDonald, Krishnan Bhaskaran, David Evans, Stephen Evans, Alex J Walker, George Hickman, Emily Nightingale, Anna Schultze, Christopher T. Rentsch, Chris Bates, Jonathan Cockburn, Helen J Curtis, Caroline E Morton, Sebastian Bacon, Simon Davy, Angel Yun Sum Wong, Amir Mehrkar, Laurie Tomlinson, Ian Douglas, Rohini Mathur, Paula Blomquist, Brian MacKenna, Peter Ingelsby, Richard Croker, John Parry, Frank Hester, Sam Harper, Nicholas J DeVito, Will Hulme, John Tazare, Ben Goldacre, Liam Smeeth, Rosalind M Eggo, (2021) Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February. Eurosurveillance (pmc: PMC7976383)(pmid: 33739254)(doi: 10.2807/1560-7917.ES.2021.26.11.2100256)(issn: 1560-7917)(wosuid: WOS:000630516500002)(source-work-id: 158158); source: London School of Hygiene and Tropical Medicine
Jeremy P Brown, John Tazare, Elizabeth Williamson, Kathryn Mansfield, Stephen Evans, Laurie Tomlinson, Krishnan Bhaskaran, Liam Smeeth, Kevin Wing, Ian Douglas, (2021) Proton pump inhibitors and risk of all-cause and cause-specific mortality: A cohort study. British Journal of Clinical Pharmacology (pmid: 33393677)(doi: 10.1111/bcp.14728)(issn: 0306-5251)(wosuid: WOS:000614528300001)(source-work-id: 155052); source: London School of Hygiene and Tropical Medicine
Kevin Wing, Elizabeth Williamson, James Carpenter, Lesley Wise, Sebastian Schneeweiss, Liam Smeeth, Jennifer K Quint, Ian Douglas, (2020) Real world effects of COPD medications: a cohort study with validation against results from randomised controlled trials. European Respiratory Journal (pmc: PMC8176192)(pmid: 33093119)(doi: 10.1183/13993003.01586-2020)(issn: 0903-1936)(wosuid: WOS:000636677200004)(source-work-id: 152047); source: London School of Hygiene and Tropical Medicine
Rohini Mathur, Christopher T. Rentsch, Caroline E Morton, William J Hulme, Anna Schultze, Brian MacKenna, Rosalind M Eggo, Krishnan Bhaskaran, Angel Yun Sum Wong, Elizabeth Williamson, Harriet Forbes, Kevin Wing, Helen McDonald, Chris Bates, Seb Bacon, Alex J Walker, David Evans, Peter Inglesby, Amir Mehrkar, Helen J Curtis, Nicholas J DeVito, Richard Croker, Henry Drysdale, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Ian Douglas, Laurie Tomlinson, Stephen Evans, Richard Grieve, David Harrison, Kathy Rowan, Kamlesh Khunti, Nishi Chaturvedi, Liam Smeeth, Ben Goldacre, OpenSAFELY Collaborative, (2020) Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform. The Lancet (pmc: PMC8087292)(pmid: 33939953)(doi: 10.1016/S0140-6736(21)00634-6)(issn: 0140-6736)(wosuid: WOS:000647813600026)(source-work-id: 151334); source: London School of Hygiene and Tropical Medicine
Oza, S., Wing, K., Sesay, A.A., Boufkhed, S., Houlihan, C., Vandi, L., Sebba, S.C., McGowan, C.R., Cummings, R., Checchi, F., (2019) Improving health information systems during an emergency: Lessons and recommendations from an Ebola treatment centre in Sierra Leone BMC Medical Informatics and Decision Making (doi: 10.1186/s12911-019-0817-9)(eid: 2-s2.0-85066396534); source: Scopus - Elsevier
Brown, J.P., Wing, K., Evans, S.J., Bhaskaran, K., Smeeth, L., Douglas, I.J., (2019) Use of real-world evidence in postmarketing medicines regulation in the European Union: A systematic assessment of European Medicines Agency referrals 2013-2017 BMJ Open (doi: 10.1136/bmjopen-2018-028133)(eid: 2-s2.0-85074266162); source: Scopus - Elsevier
Fitzgerald, F., Wing, K., Naveed, A., Gbessay, M., Ross, J.C.G., Checchi, F., Youkee, D., Jalloh, M.B., Baion, D.E., Mustapha, A., Jah, H., Lako, S., Oza, S., Boufkhed, S., Feury, R., Bielicki, J., Williamson, E., Gibb, D.M., Klein, N., Sahr, F., Yeung, S., (2018) Development of a pediatric ebola predictive score, Sierra Leone Emerging Infectious Diseases (doi: 10.3201/eid2402.171018)(eid: 2-s2.0-85040929048); source: Scopus - Elsevier
Wing, K., Williamson, E., Carpenter, J.R., Wise, L., Schneeweiss, S., Smeeth, L., Quint, J.K., Douglas, I., (2018) Real-world effects of medications for chronic obstructive pulmonary disease: Protocol for a UK population-based non-interventional cohort study with validation against randomised trial results BMJ Open (doi: 10.1136/bmjopen-2017-019475)(eid: 2-s2.0-85053069226); source: Scopus - Elsevier
Wing, K., Oza, S., Houlihan, C., Glynn, J.R., Irvine, S., Warrell, C.E., Simpson, A.J.H., Boufkhed, S., Sesay, A., Vandi, L., Sebba, S.C., Shetty, P., Cummings, R., Checchi, F., McGowan, C.R., (2018) Surviving Ebola: A historical cohort study of Ebola mortality and survival in Sierra Leone 2014-2015 PLoS ONE (doi: 10.1371/journal.pone.0209655)(eid: 2-s2.0-85059234284); source: Scopus - Elsevier
Langan, S.M., Schmidt, S.A., Wing, K., Ehrenstein, V., Nicholls, S.G., Filion, K.B., Klungel, O., Petersen, I., Sorensen, H.T., Dixon, W.G., Guttmann, A., Harron, K., Hemkens, L.G., Moher, D., Schneeweiss, S., Smeeth, L., Sturkenboom, M., von Elm, E., Wang, S.V., Benchimol, E.I., (2018) The reporting of studies conducted using observational routinely collected health data statement for pharmacoepidemiology (RECORD-PE) BMJ (Clinical research ed.) (doi: 10.1136/bmj.k3532)(eid: 2-s2.0-85056647922); source: Scopus - Elsevier
Oza, S., Jazayeri, D., Teich, J.M., Ball, E., Nankubuge, P.A., Rwebembera, J., Wing, K., Sesay, A.A., Kanter, A.S., Ramos, G.D., Walton, D., Cummings, R., Checchi, F., Fraser, H.S., (2017) Development and deployment of the OpenMRS-Ebola electronic health record system for an Ebola treatment center in Sierra Leone Journal of Medical Internet Research (doi: 10.2196/jmir.7881)(eid: 2-s2.0-85029366661); source: Scopus - Elsevier
Wing, K., Bhaskaran, K., Pealing, L., Root, A., Smeeth, L., van Staa, T.P., Klungel, O.H., Reynolds, R.F., Douglas, I., (2017) Quantification of the risk of liver injury associated with flucloxacillin: A UK population-based cohort study Journal of Antimicrobial Chemotherapy (doi: 10.1093/jac/dkx183)(eid: 2-s2.0-85044929835); source: Scopus - Elsevier
Fitzgerald, F., Wing, K., Naveed, A., Gbessay, M., Ross, J.C.G., Checchi, F., Youkee, D., Jalloh, M.B., Baion, D., Mustapha, A., Jah, H., Lako, S., Oza, S., Boufkhed, S., Feury, R., Bielicki, J., Williamson, E., Gibb, D.M., Klein, N., Sahr, F., Yeung, S., (2017) Risk in the "red Zone": Outcomes for Children Admitted to Ebola Holding Units in Sierra Leone Without Ebola Virus Disease Clinical Infectious Diseases (doi: 10.1093/cid/cix223)(eid: 2-s2.0-85020382047); source: Scopus - Elsevier
Oza, S., Sesay, A.A., Russell, N.J., Wing, K., Boufkhed, S., Vandi, L., Sebba, S.C., Cummings, R., Checchi, F., (2017) Symptom-and laboratory-based ebola risk scores to differentiate likely ebola infections Emerging Infectious Diseases (doi: 10.3201/eid2311.170171)(eid: 2-s2.0-85032014404); source: Scopus - Elsevier
Bastawrous, A., Mathenge, W., Wing, K., Bastawrous, M., Rono, H., Weiss, H.A., Macleod, D., Foster, A., Peto, T., Blows, P., Burton, M., Kuper, H., (2017) The incidence of diabetes mellitus and diabetic retinopathy in a population-based cohort study of people age 50 years and over in Nakuru, Kenya BMC endocrine disorders (doi: 10.1186/s12902-017-0170-x)(eid: 2-s2.0-85029288695); source: Scopus - Elsevier
Fitzgerald, F., Baion, D.E., Wing, K., Yeung, S., Sahr, F., (2017) The predicament of patients with suspected Ebola The Lancet Global Health (doi: 10.1016/S2214-109X(17)30209-7)(eid: 2-s2.0-85020465447); source: Scopus - Elsevier
Fitzgerald, F., Naveed, A., Wing, K., Gbessay, M., Ross, J.C.G., Checchi, F., Youkee, D., Jalloh, M.B., Baion, D., Mustapha, A., Jah, H., Lako, S., Oza, S., Boufkhed, S., Feury, R., Bielicki, J.A., Gibb, D.M., Klein, N., Sahr, F., Yeung, S., (2016) Ebola virus disease in children, Sierra Leone, 2014–2015 Emerging Infectious Diseases (doi: 10.3201/eid2210.160579)(eid: 2-s2.0-84988517536); source: Scopus - Elsevier
Wing, K., Bhaskaran, K., Smeeth, L., van Staa, T.P., Klungel, O.H., Reynolds, R.F., Douglas, I., (2016) Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury BMJ open (doi: 10.1136/bmjopen-2016-012102)(eid: 2-s2.0-85019996090); source: Scopus - Elsevier
Pealing, L., Wing, K., Mathur, R., Prieto-Merino, D., Smeeth, L., Moore, D.A.J., (2015) Risk of tuberculosis in patients with diabetes: Population based cohort study using the UK Clinical Practice Research Datalink BMC Medicine (doi: 10.1186/s12916-015-0381-9)(eid: 2-s2.0-84935905936); source: Scopus - Elsevier
Wing, K., Douglas, I., Bhaskaran, K., Klungel, O.H., Reynolds, R.F., Pirmohamed, M., Smeeth, L., Van Staa, T.P., (2014) Development of predictive genetic tests for improving the safety of new medicines: The utilization of routinely collected electronic health records Drug Discovery Today (doi: 10.1016/j.drudis.2013.11.003)(eid: 2-s2.0-84899537758); source: Scopus - Elsevier
Kuper, H., Dok, A.M.V., Wing, K., Danquah, L., Evans, J., Zuurmond, M., Gallinetti, J., (2014) The Impact of disability on the lives of children; Cross-sectional data including 8,900 children with disabilities and 898,834 children without disabilities across 30 countries PLoS ONE (doi: 10.1371/journal.pone.0107300)(eid: 2-s2.0-84929939443); source: Scopus - Elsevier
Paudel, P., Wing, K., Silpakar, S.K., (2012) Awareness of periconceptional folic acid supplementation among Nepalese women of childbearing age: A cross-sectional study Preventive Medicine (doi: 10.1016/j.ypmed.2012.09.001)(eid: 2-s2.0-84868302083); source: Scopus - Elsevier
Supervision
Current PhD/DrPH projects that I supervise are listed below, along with those that I have recently supervised to completion.
Current:
- Investigating the evidence for pharmacogenomic implementation in the NHS in Scotland (UoG)
- Emulating randomized trials in observational data to determine ethnic differences in the effects of type 2 diabetes treatments (QMUL)
- Are women negatively impacted by differences in safety and effectiveness of medicines compared to men? (LSHTM)
Completed:
- Real-world effectiveness of oral anticoagulants in the prevention of stroke: emulation and extension of the ARISTOTLE trial using UK EHRs (LSHTM, 2024)
- Real-world effectiveness and adverse events caused by ACE inhibitors and ARBs for reduction in cardiovascular events with validation against the ONTARGET trial (LSHTM, 2023)
- Application of methods for handling unmeasured confounding in pharmacoepidemiological studies (LSHTM, 2023)
Teaching
I teach epidemiology on the Masters of Public Health (MPH) at Glasgow, and in an honorary capacity teach pharmacoepidemiology on the LSHTM Professional Certificate in Pharmacoepidemiology and Pharmacovigilance (a course that I have previously co-led). I am also involved in the supervision of PhD and MPH students.
Professional activities & recognition
Professional & learned societies
- 2020: Associate Fellow, Higher Education Academy