Dr Oana Dobre

  • Lecturer Biomedical Engineering (Biomedical Engineering)

email: Oana.Dobre@glasgow.ac.uk

Advanced Research Centre, 11 Chapel Lane, 4127 office, G11 6EW

Import to contacts

ORCID iDhttps://orcid.org/0000-0003-1968-5428

Biography

Oana holds a PhD in Mechanical Engineering (Tribology) from Imperial College London. After her doctoral studies, she worked as a Research Associate at the University of Manchester for two years, where she became fascinated by mechanobiological research and developed an expertise in biology to complement her extensive engineering background. From 2017 to 2022, Oana was a Research Associate at the Centre for the Cellular Microenvironment (CeMi) at the University of Glasgow. Her research focused on developing and characterizing full-length protein-based hydrogels for efficient growth factor delivery for tissue engineering applications, with a particular emphasis on bone tissue regeneration, spinal cord injuries, and vascularization. She started a Lecturer in Biomedical Engineering position at the University of Glasgow in 2022.

Publications

List by: Type | Date

Jump to: 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2016 | 2015
Number of items: 25.

2023

Parra-Torrejón, B., Jayawarna, V., Rodrigo-Navarro, A. , Gonzalez, J., Dobre, O. , Ramírez-Rodríguez, G. B., Salmeron-Sanchez, M. and Delgado-López, J. M. (2023) Bioinspired mineralization of engineered living materials to promote osteogenic differentiation. Biomaterials Advances, 154, 213587. (doi: 10.1016/j.bioadv.2023.213587) (PMID:37633007)

Sarrigiannidis, S. O., Dobre, O. , Navarro, A. R., Dalby, M. J. , Gonzalez-Garcia, C. and Salmeron-Sanchez, M. (2023) Engineered dual affinity protein fragments to bind collagen and capture growth factors. Materials Today Bio, 20, 100641. (doi: 10.1016/j.mtbio.2023.100641) (PMID:37179535) (PMCID:PMC10173277)

2022

Moxon, S. R., Richards, D., Dobre, O. , Wong, L. S., Swift, J. and Richardson, S. M. (2022) Regulation of mesenchymal stem cell morphology using hydrogel substrates with tunable topography and photoswitchable stiffness. Polymers, 14(24), 5338. (doi: 10.3390/polym14245338) (PMID:36559706) (PMCID:PMC9788018)

Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biomaterials to engineer hematopoietic stem cell niches. Advanced Healthcare Materials, 11(20), 2200964. (doi: 10.1002/adhm.202200964) (PMID:35933595)

Monferrer Garzarán, E., Dobre, O. , Trujillo, S. , Azevedo González Oliva, M., Trubert-Paneli, A., Acevedo-León, D., Noguera, R. and Salmeron-Sanchez, M. (2022) Vitronectin-based hydrogels recapitulate neuroblastoma growth conditions. Frontiers in Cell and Developmental Biology, 10, 988699. (doi: 10.3389/fcell.2022.988699) (PMID:36425532) (PMCID:PMC9679952)

Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biointerfaces for the maintenance of mesenchymal stem cell phenotypes. Advanced Functional Materials, 32(32), 2203352. (doi: 10.1002/adfm.202203352)

Domingo-Roca, R., Gilmour, L., Dobre, O. , Sarrigiannidis, S., Sandison, M. E., O'Leary, R. and Mulvana, H. E. (2022) 3D printing of noncytotoxic high-resolution microchannels in Bisphenol-a ethoxylate dimethacrylate tissue-mimicking materials. 3D Printing and Additive Manufacturing, 10(5), pp. 1101-1109. (doi: 10.1089/3dp.2021.0235) (PMID:37886413)

Domingo-Roca, R., Gilmour, L., Asciak, L., Sarrigiannidis, S., Dobre, O. , Salmeron-Sanchez, M. , Sandison, M., O'Leary, R., Jackson-Camargo, J. and Mulvana, H. (2022) 3D-printed High-resolution Microchannels for Contrast Enhanced Ultrasound Research. In: 2021 IEEE International Ultrasonics Symposium (IUS), Xi'an, China, 11-16 Sep2021, ISBN 9781665403559 (doi: 10.1109/ius52206.2021.9763442)

2021

Hajiali, H., Ouyang, L., Llopis-Hernandez, V. , Dobre, O. and Rose, F. R. A. J. (2021) Review of emerging nanotechnology in bone regeneration: progress, challenges, and perspectives. Nanoscale, 13(23), pp. 10266-10280. (doi: 10.1039/D1NR01371H) (PMID:34085085)

Dobre, O. et al. (2021) A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors – neural growth and osteogenesis. Advanced Functional Materials, 31(21), 2010225. (doi: 10.1002/adfm.202010225)

Sarrigiannidis, S. O., Rey, J. M., Dobre, O. , Gonzalez Garcia, C., Dalby, M. J. and Salmeron-Sanchez, M. (2021) A tough act to follow: collagen hydrogel modifications to improve mechanical and growth factor loading capabilities. Materials Today Bio, 10, 100098. (doi: 10.1016/j.mtbio.2021.100098) (PMID:33763641) (PMCID:PMC7973388)

2020

Lüchtefeld, I., Bartolozzi, A., Mejía Morales, J., Dobre, O. , Basso, M., Zambelli, T. and Vassalli, M. (2020) Elasticity spectra as a tool to investigate actin cortex mechanics. Journal of Nanobiotechnology, 18, 147. (doi: 10.1186/s12951-020-00706-2)

Ciccone, G., Dobre, O. , Gibson, G. M. , Rey, J. M., Gonzalez-Garcia, C., Vassalli, M. , Salmeron-Sanchez, M. and Tassieri, M. (2020) What caging force cells feel in 3D hydrogels: a rheological perspective. Advanced Healthcare Materials, 9(17), 2000517. (doi: 10.1002/adhm.202000517) (PMID:32696605)

Sarrigiannidis, S. O., Moussa, H., Dobre, O. , Dalby, M. J. , Tamimi, F. and Salmerón-Sánchez, M. (2020) Chiral tartaric acid improves fracture toughness of bioactive brushite-collagen bone cements. ACS Applied Bio Materials, 3(8), pp. 5056-5066. (doi: 10.1021/acsabm.0c00555) (PMID:32904797) (PMCID:PMC7461128)

2019

Hetmanski, J. H.R. et al. (2019) Membrane tension orchestrates rear retraction in matrix directed cell migration. Developmental Cell, 51(4), 460-475.e10. (doi: 10.1016/j.devcel.2019.09.006) (PMID:31607653) (PMCID:PMC6863396)

Gilbert, H. T. J., Mallikarjun, V., Dobre, O. , Jackson, M. R. , Pedley, R., Gilmore, A. P., Richardson, S. M. and Swift, J. (2019) Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading. Nature Communications, 10, 4149. (doi: 10.1038/s41467-019-11923-1) (PMID:31515493) (PMCID:PMC6742657)

Trujillo, S. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2019) Mechanotransduction and growth factor signaling in hydrogel-based microenvironments. In: Encyclopedia of Tissue Engineering and Regenerative Medicine. Elsevier, pp. 87-101. ISBN 9780128137000 (doi: 10.1016/B978-0-12-801238-3.11141-9)

2018

Galarza Torre, A., Shaw, J. E., Wood, A., Gilbert, H. T.J., Dobre, O. , Genever, P., Brennan, K., Richardson, S. M. and Swift, J. (2018) An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness. Scientific Reports, 8, 8981. (doi: 10.1038/s41598-018-27346-9) (PMID:29895825) (PMCID:PMC5997644)

Lee, I.-N., Dobre, O. , Richards, D., Ballestrem, C., Curran, J. M., Hunt, J. A., Richardson, S. M., Swift, J. and Wong, L. S. (2018) Photoresponsive hydrogels with photoswitchable mechanical properties allow time-resolved analysis of cellular responses to matrix stiffening. ACS Applied Materials and Interfaces, 10(9), pp. 7765-7776. (doi: 10.1021/acsami.7b18302) (PMID:29430919) (PMCID:PMC5864053)

Dobre, O. (2018) Hybrid Laminin Hydrogels for Bone Regeneration. BMeeting of the Glasgow Orthopaedic Research Initiative (GLORI 2018), Glasgow, UK, 23rd February 2018.

2016

Dobre, O. , Lee, I.-N., Wong, L.S., Richards, D., Jackson, M.R., Gilbert, H.T.J., Richardson, S. and Swift, J. (2016) Photoresponsive hydrogels with reversible mechanical properties allow time‐resolved analysis of cellular responses to matrix stiffening. British Society for Matrix Biology Autumn 2016 Meeting, Cardiff, Wales, 5-6 Sept 2016. (doi: 10.1111/iep.12218)

Gilbert, H.T.J., Mallikarjun, V., Dobre, O. , Cho, I., Jackson, M.R. and Swift, J. (2016) Nuclear decoupling and chaperones protect cell homeostasis during mechanical loading. British Society for Matrix Biology Autumn 2016 Meeting, Cardiff, Wales, 5-6 Sept 2016. (doi: 10.1111/iep.12218)

Mallikarjun, V., Gilbert, H.T.J., Dobre, O. , Jackson, M.R. and Swift, J. (2016) Proteomic methods to study the effect of ageing on matrix and mechanotransduction pathways. British Society for Matrix Biology Autumn 2016 Meeting, Cardiff, Wales, 5-6 Sept 2016. (doi: 10.1111/iep.12218)

Swift, J., Dobre, O. , Jackson, M.R., Mallikarjun, V. and Gilbert, H.T.J. (2016) Mass spectrometry methods reveal a stiffness‐responsive extracellular matrix proteome, but mechanosensitivity is modulated in senescence. British Society for Matrix Biology Autumn 2016 Meeting, Cardiff, Wales, 5-6 Sept 2016. (doi: 10.1111/iep.12218)

2015

Reddyhoff, T., Dobre, O. , Le Rouzic, J., Gotzen, N.-A., Parton, H. and Dini, D. (2015) Friction induced vibration in windscreen wiper contacts. Journal of Vibration and Acoustics, 137(4), 041009. (doi: 10.1115/1.4029987)

This list was generated on Thu Nov 21 03:05:45 2024 GMT.
Jump to: Articles | Book Sections | Conference or Workshop Item | Conference Proceedings
Number of items: 25.

Articles

Parra-Torrejón, B., Jayawarna, V., Rodrigo-Navarro, A. , Gonzalez, J., Dobre, O. , Ramírez-Rodríguez, G. B., Salmeron-Sanchez, M. and Delgado-López, J. M. (2023) Bioinspired mineralization of engineered living materials to promote osteogenic differentiation. Biomaterials Advances, 154, 213587. (doi: 10.1016/j.bioadv.2023.213587) (PMID:37633007)

Sarrigiannidis, S. O., Dobre, O. , Navarro, A. R., Dalby, M. J. , Gonzalez-Garcia, C. and Salmeron-Sanchez, M. (2023) Engineered dual affinity protein fragments to bind collagen and capture growth factors. Materials Today Bio, 20, 100641. (doi: 10.1016/j.mtbio.2023.100641) (PMID:37179535) (PMCID:PMC10173277)

Moxon, S. R., Richards, D., Dobre, O. , Wong, L. S., Swift, J. and Richardson, S. M. (2022) Regulation of mesenchymal stem cell morphology using hydrogel substrates with tunable topography and photoswitchable stiffness. Polymers, 14(24), 5338. (doi: 10.3390/polym14245338) (PMID:36559706) (PMCID:PMC9788018)

Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biomaterials to engineer hematopoietic stem cell niches. Advanced Healthcare Materials, 11(20), 2200964. (doi: 10.1002/adhm.202200964) (PMID:35933595)

Monferrer Garzarán, E., Dobre, O. , Trujillo, S. , Azevedo González Oliva, M., Trubert-Paneli, A., Acevedo-León, D., Noguera, R. and Salmeron-Sanchez, M. (2022) Vitronectin-based hydrogels recapitulate neuroblastoma growth conditions. Frontiers in Cell and Developmental Biology, 10, 988699. (doi: 10.3389/fcell.2022.988699) (PMID:36425532) (PMCID:PMC9679952)

Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biointerfaces for the maintenance of mesenchymal stem cell phenotypes. Advanced Functional Materials, 32(32), 2203352. (doi: 10.1002/adfm.202203352)

Domingo-Roca, R., Gilmour, L., Dobre, O. , Sarrigiannidis, S., Sandison, M. E., O'Leary, R. and Mulvana, H. E. (2022) 3D printing of noncytotoxic high-resolution microchannels in Bisphenol-a ethoxylate dimethacrylate tissue-mimicking materials. 3D Printing and Additive Manufacturing, 10(5), pp. 1101-1109. (doi: 10.1089/3dp.2021.0235) (PMID:37886413)

Hajiali, H., Ouyang, L., Llopis-Hernandez, V. , Dobre, O. and Rose, F. R. A. J. (2021) Review of emerging nanotechnology in bone regeneration: progress, challenges, and perspectives. Nanoscale, 13(23), pp. 10266-10280. (doi: 10.1039/D1NR01371H) (PMID:34085085)

Dobre, O. et al. (2021) A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors – neural growth and osteogenesis. Advanced Functional Materials, 31(21), 2010225. (doi: 10.1002/adfm.202010225)

Sarrigiannidis, S. O., Rey, J. M., Dobre, O. , Gonzalez Garcia, C., Dalby, M. J. and Salmeron-Sanchez, M. (2021) A tough act to follow: collagen hydrogel modifications to improve mechanical and growth factor loading capabilities. Materials Today Bio, 10, 100098. (doi: 10.1016/j.mtbio.2021.100098) (PMID:33763641) (PMCID:PMC7973388)

Lüchtefeld, I., Bartolozzi, A., Mejía Morales, J., Dobre, O. , Basso, M., Zambelli, T. and Vassalli, M. (2020) Elasticity spectra as a tool to investigate actin cortex mechanics. Journal of Nanobiotechnology, 18, 147. (doi: 10.1186/s12951-020-00706-2)

Ciccone, G., Dobre, O. , Gibson, G. M. , Rey, J. M., Gonzalez-Garcia, C., Vassalli, M. , Salmeron-Sanchez, M. and Tassieri, M. (2020) What caging force cells feel in 3D hydrogels: a rheological perspective. Advanced Healthcare Materials, 9(17), 2000517. (doi: 10.1002/adhm.202000517) (PMID:32696605)

Sarrigiannidis, S. O., Moussa, H., Dobre, O. , Dalby, M. J. , Tamimi, F. and Salmerón-Sánchez, M. (2020) Chiral tartaric acid improves fracture toughness of bioactive brushite-collagen bone cements. ACS Applied Bio Materials, 3(8), pp. 5056-5066. (doi: 10.1021/acsabm.0c00555) (PMID:32904797) (PMCID:PMC7461128)

Hetmanski, J. H.R. et al. (2019) Membrane tension orchestrates rear retraction in matrix directed cell migration. Developmental Cell, 51(4), 460-475.e10. (doi: 10.1016/j.devcel.2019.09.006) (PMID:31607653) (PMCID:PMC6863396)

Gilbert, H. T. J., Mallikarjun, V., Dobre, O. , Jackson, M. R. , Pedley, R., Gilmore, A. P., Richardson, S. M. and Swift, J. (2019) Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading. Nature Communications, 10, 4149. (doi: 10.1038/s41467-019-11923-1) (PMID:31515493) (PMCID:PMC6742657)

Galarza Torre, A., Shaw, J. E., Wood, A., Gilbert, H. T.J., Dobre, O. , Genever, P., Brennan, K., Richardson, S. M. and Swift, J. (2018) An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness. Scientific Reports, 8, 8981. (doi: 10.1038/s41598-018-27346-9) (PMID:29895825) (PMCID:PMC5997644)

Lee, I.-N., Dobre, O. , Richards, D., Ballestrem, C., Curran, J. M., Hunt, J. A., Richardson, S. M., Swift, J. and Wong, L. S. (2018) Photoresponsive hydrogels with photoswitchable mechanical properties allow time-resolved analysis of cellular responses to matrix stiffening. ACS Applied Materials and Interfaces, 10(9), pp. 7765-7776. (doi: 10.1021/acsami.7b18302) (PMID:29430919) (PMCID:PMC5864053)

Reddyhoff, T., Dobre, O. , Le Rouzic, J., Gotzen, N.-A., Parton, H. and Dini, D. (2015) Friction induced vibration in windscreen wiper contacts. Journal of Vibration and Acoustics, 137(4), 041009. (doi: 10.1115/1.4029987)

Book Sections

Trujillo, S. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2019) Mechanotransduction and growth factor signaling in hydrogel-based microenvironments. In: Encyclopedia of Tissue Engineering and Regenerative Medicine. Elsevier, pp. 87-101. ISBN 9780128137000 (doi: 10.1016/B978-0-12-801238-3.11141-9)

Conference or Workshop Item

Dobre, O. (2018) Hybrid Laminin Hydrogels for Bone Regeneration. BMeeting of the Glasgow Orthopaedic Research Initiative (GLORI 2018), Glasgow, UK, 23rd February 2018.

Dobre, O. , Lee, I.-N., Wong, L.S., Richards, D., Jackson, M.R., Gilbert, H.T.J., Richardson, S. and Swift, J. (2016) Photoresponsive hydrogels with reversible mechanical properties allow time‐resolved analysis of cellular responses to matrix stiffening. British Society for Matrix Biology Autumn 2016 Meeting, Cardiff, Wales, 5-6 Sept 2016. (doi: 10.1111/iep.12218)

Gilbert, H.T.J., Mallikarjun, V., Dobre, O. , Cho, I., Jackson, M.R. and Swift, J. (2016) Nuclear decoupling and chaperones protect cell homeostasis during mechanical loading. British Society for Matrix Biology Autumn 2016 Meeting, Cardiff, Wales, 5-6 Sept 2016. (doi: 10.1111/iep.12218)

Mallikarjun, V., Gilbert, H.T.J., Dobre, O. , Jackson, M.R. and Swift, J. (2016) Proteomic methods to study the effect of ageing on matrix and mechanotransduction pathways. British Society for Matrix Biology Autumn 2016 Meeting, Cardiff, Wales, 5-6 Sept 2016. (doi: 10.1111/iep.12218)

Swift, J., Dobre, O. , Jackson, M.R., Mallikarjun, V. and Gilbert, H.T.J. (2016) Mass spectrometry methods reveal a stiffness‐responsive extracellular matrix proteome, but mechanosensitivity is modulated in senescence. British Society for Matrix Biology Autumn 2016 Meeting, Cardiff, Wales, 5-6 Sept 2016. (doi: 10.1111/iep.12218)

Conference Proceedings

Domingo-Roca, R., Gilmour, L., Asciak, L., Sarrigiannidis, S., Dobre, O. , Salmeron-Sanchez, M. , Sandison, M., O'Leary, R., Jackson-Camargo, J. and Mulvana, H. (2022) 3D-printed High-resolution Microchannels for Contrast Enhanced Ultrasound Research. In: 2021 IEEE International Ultrasonics Symposium (IUS), Xi'an, China, 11-16 Sep2021, ISBN 9781665403559 (doi: 10.1109/ius52206.2021.9763442)

This list was generated on Thu Nov 21 03:05:45 2024 GMT.

Research datasets

Jump to: 2022 | 2020
Number of items: 2.

2022

Salmeron-Sanchez, M. , Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. and Dalby, M. (2022) Living Biomaterials to Engineer Hematopoietic Stem Cell Niches. [Data Collection]

2020

Lüchtefeld, I., Bartolozzi, A., Mejiá, J., Dobre, O. , Basso, M., Zambelli, T. and Vassalli, M. (2020) Elasticity Spectra as a Tool to Investigate Actin Cortex Mechanics. [Data Collection]

This list was generated on Thu Nov 21 03:05:47 2024 GMT.