Professor Massimo Vassalli
- Professor of Bioengineering (Biomedical Engineering)
telephone:
01413302000
email:
Massimo.Vassalli@glasgow.ac.uk
Level 4, Advanced Research Centre, 11 Chapel Lane, G11 6EW
https://orcid.org/0000-0002-3063-4376Biography
I graduated in Physics at the University of Florence (Italy) in 1999, including an instructive 1 year Erasmus experience at the University of Mainz (Germany). After the degree, I initially moved to the industry, working in the area of informatics and supporting the birth of a small company in the field. I quickly realized I would better enjoy the academic pathway and I decided to enroll in a cross-disciplinary PhD program between physics, engineering and biology at the University of Florence, and working at the Biophotonics Lab of the National Institute of Applied Optics. I then spent few years as research fellow inside different Italian national research institutes, learning and exploiting advanced optical microscopy and force spectroscopy techniques for the study of biological systems (molecules and cells). During 2009 I moved to the Institute of Biophysics ot the National Research Council in Genova, where I had the opportunity to cultivate my interest on "mechanics in biology". In the meantime, I never gave up the industrial experience and I supported technology transfer and innovation, leading to an increased network of interactions with national and international companies.
Since October 2019 I joined the School of Engineering of the University of Glasgow, to participate to the scientific activities of the Centre for the Cellular Microenvironment led by Prof Manuel Salmeron-Sanchez and Prof Matthew Dalby.
You can find more details on my scientific journey in the january 2021 edition of the "Meet the Editor" series of Biophysical Reviews.
Research interests
My general research interest is in understanding the mechanisms by which physical forces are transduced into biologically relevant signals (mechanotransduction), and their role in the homoeostasis of key physiological processes whose alteration eventually leads to pathology or degeneration, such as in cancer or ageing (mechanobiology). Moreover, exploiting my technical background in physics and engineering, I'm also committed in developing enabling microscopy and spectroscopy tools to measure mechanical properties, image and manipulate biological objects at the level of cells and molecules (nanoengineering).
You can have more details heading to the the Cellular Mechanobiology Lab website.
Publications
Selected publications
Morales, J. M., Hammarström, B., Lippi, G. L., Vassalli, M. and Glynne-Jones, P. (2021) Acoustofluidic phase microscopy in a tilted segmentation-free configuration. Biomicrofluidics, 15(1), 014102. (doi: 10.1063/5.0036585)
Mattarelli, M., Vassalli, M. and Caponi, S. (2020) Relevant length scales in Brillouin imaging of biomaterials: the interplay between phonons propagation and light focalization. ACS Photonics, 7(9), pp. 2319-2328. (doi: 10.1021/acsphotonics.0c00801)
Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
Ridone, P., Pandzic, E., Vassalli, M. , Cox, C. D., Macmillan, A., Gottlieb, P. A. and Martinac, B. (2020) Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters. Journal of General Physiology, 152(8), e201912515. (doi: 10.1085/jgp.201912515) (PMID:32582958)
Lüchtefeld, I., Bartolozzi, A., Mejía Morales, J., Dobre, O. , Basso, M., Zambelli, T. and Vassalli, M. (2020) Elasticity spectra as a tool to investigate actin cortex mechanics. Journal of Nanobiotechnology, 18, 147. (doi: 10.1186/s12951-020-00706-2)
All publications
2025
Binner, P. , Starshynov, I. , Tejeda, G. , McFall, A. , Molloy, C. , Ciccone, G., Walker, M. , Vassalli, M. , Tobin, A. B. and Faccio, D. (2025) Optical, contact-free assessment of brain tissue stiffness and neurodegeneration. Biomedical Optics Express, 16(2), pp. 447-459. (doi: 10.1364/BOE.545580)
Ciccone, G., Azevedo Gonzalez Oliva, M., Versaevel, M., Cantini, M. , Vassalli, M. , Salmeron-Sanchez, M. and Gabriele, S. (2025) Epithelial cell mechanoresponse to matrix viscoelasticity and confinement within micropatterned viscoelastic hydrogels. Advanced Science, (Accepted for Publication)
Gelli, M., Tiribilli, B., Salam, F. A., Vassalli, M. and Basso, M. (2025) Adaptive drive as a control strategy for fast scanning in dynamic mode atomic force microscopy. Sensors, 25(3), 860. (doi: 10.3390/s25030860)
2024
Tan, M. et al. (2024) Polyetherureas as aqueous binders for Li ion batteries. ChemRxiv, (doi: 10.26434/chemrxiv-2024-mk39b)
Cubero-Sarabia, M., Kapetanaki, A. M. and Vassalli, M. (2024) Biophysical assays to test cellular mechanosensing: moving towards high throughput. Biophysical Reviews, (Accepted for Publication)
Cubero-Sarabia, M., Kapetanaki, A. M. and Vassalli, M. (2024) Biophysical assays to test cellular mechanosensing: moving towards high throughput. Biophysical Reviews, 16(6), pp. 875-882. (doi: 10.1007/s12551-024-01263-w) (PMID:39830126) (PMCID:PMC11735701)
Giampietro, C., Ferrari, A. and Vassalli, M. (2024) Editorial to the topical issue: the 7th Nanoengineering for Mechanobiology Symposium 2024 Camogli, Genoa, Italy. Biophysical Reviews, 16(6), pp. 831-832. (doi: 10.1007/s12551-024-01262-x) (PMID:39830131)
Kulyabin, P., Magdysyuk, O. V., Naden, A. B., McLean Dawson, D., Pancholi, K., Walker, M. , Vassalli, M. and Kumar, A. (2024) Manganese-catalyzed synthesis of polyketones using hydrogen-borrowing approach. ACS Catalysis, 14, pp. 10624-10634. (doi: 10.1021/acscatal.4c03019) (Early Online Publication)
Morena, F., Argentati, C., Caponi, S., Lüchtefeld, I., Emiliani, C., Vassalli, M. and Martino, S. (2024) Piezo1 – serine/threonine-protein phosphatase 2A – Cofilin1 biochemical mechanotransduction axis controls F-actin dynamics and cell migration. Heliyon, 10(11), e32458. (doi: 10.1016/j.heliyon.2024.e32458) (PMID:38933959) (PMCID:PMC11201121)
Lüchtefeld, I. et al. (2024) Dissecting cell membrane tension dynamics and its effect on Piezo1-mediated cellular mechanosensitivity using force-controlled nanopipettes. Nature Methods, 21(6), pp. 1063-1073. (doi: 10.1038/s41592-024-02277-8) (PMID:38802520)
Ghosh, D. , Coulter, S. M., Laverty, G., Holland, C., Doutch, J. J., Vassalli, M. and Adams, D. J. (2024) Metal cross-linked supramolecular gel noodles: structural insights and antibacterial assessment. Biomacromolecules, 25(5), pp. 3169-3177. (doi: 10.1021/acs.biomac.4c00300) (PMID:38684138) (PMCID:PMC11094724)
Giampietro, C., Ferrari, A. and Vassalli, M. (2024) Biophysical Reviews’ topical issue: the 7th Nanoengineering for Mechanobiology Symposium 2024 Camogli, Genoa, Italy. Biophysical Reviews, 16(2), pp. 149-150. (doi: 10.1007/s12551-024-01193-7) (PMID:38737207) (PMCID:PMC11078896)
2023
Bonnefond, S., Reynaud, A., Cazareth, J., Abélanet, S., Vassalli, M. , Brau, F. and Lippi, G. L. (2023) Nanoscatterer-assisted fluorescence amplification technique. Nanomaterials, 13(21), 2875. (doi: 10.3390/nano13212875) (PMID:37947721)
Ghosh, D. , Marshall, L. J., Ciccone, G., Liu, W., Squires, A., Seddon, A., Vassalli, M. and Adams, D. J. (2023) Fine-tuning supramolecular assemblies by controlling micellar aggregates. Macromolecular Materials and Engineering, 308(10), 2300082. (doi: 10.1002/mame.202300082)
Viti, F. et al. (2023) Multi-disciplinary insights from the First European Forum on Visceral Myopathy 2022 Meeting. Digestive Diseases and Sciences, 68, pp. 3857-3871. (doi: 10.1007/s10620-023-08066-1) (PMID:37650948) (PMCID:PMC10517037)
Viti, F. et al. (2023) Patient's dermal fibrolasts as disease markers for visceral myopathy. Biomaterials Advances, 148, 213355. (doi: 10.1016/j.bioadv.2023.213355)
Marshall, L. J., Wallace, M., Mahmoudi, N., Ciccone, G., Wilson, C. , Vassalli, M. and Adams, D. J. (2023) Hierarchical composite self-sorted supramolecular gel noodles. Advanced Materials, 35(17), 2211277. (doi: 10.1002/adma.202211277) (PMID:36720202)
Zambito, M., Viti, F., Bosio, A. G., Ceccherini, I., Florio, T. and Vassalli, M. (2023) The impact of experimental conditions on cell mechanics as measured with nanoindentation. Nanomaterials, 13(7), 1190. (doi: 10.3390/nano13071190)
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
Grandy, C., Port, F., Pfeil, J., Azevedo Gonzalez Oliva, M., Vassalli, M. and Gottschalk, K.-E. (2023) Cell shape and tension alter focal adhesion structure. Biomaterials Advances, 145, 213277. (doi: 10.1016/j.bioadv.2022.213277)
Keith, N. et al. (2023) Regenerative Futures: From Global to Local Development in 2032. [Exhibitions]
2022
Mouro, J., Paoletti, P., Sartore, M., Vassalli, M. and Tiribilli, B. (2022) Photothermal self-excitation of a phase-controlled microcantilever for viscosity or viscoelasticity sensing. Sensors, 22(21), 8421. (doi: 10.3390/s22218421) (PMID:36366122)
Capponi, G., Zambito, M., Neri, I., Cottone, F., Mattarelli, M., Vassalli, M. , Caponi, S. and Florio, T. (2022) Cellular mechanosensitivity: validation of an adaptable 3d-printed device for microindentation. Nanomaterials, 12(15), 2691. (doi: 10.3390/nano12152691)
Baldini, F., Khalil, M., Bartolozzi, A., Vassalli, M. , Di Ciaula, A., Portincasa, P. and Vergani, L. (2022) Relationship between liver stiffness and steatosis in obesity conditions: in vivo and in vitro studies. Biomolecules, 12(5), 733. (doi: 10.3390/biom12050733)
Caponi, S., Passeri, A., Capponi, G., Fioretto, D., Vassalli, M. and Mattarelli, M. (2022) Non-contact elastography methods in mechanobiology: a point of view. European Biophysics Journal, 51(2), pp. 99-104. (doi: 10.1007/s00249-021-01567-9) (PMID:34463775)
Mejia Morales, J., Glynne-Jones, P., Vassalli, M. and Lippi, G.L. (2022) Acoustofluidic interferometric device for rapid single cell physical phenotyping. European Biophysics Journal, 51(2), pp. 185-191. (doi: 10.1007/s00249-021-01585-7) (PMID:35018482)
Sforna, L., Michelucci, A., Morena, F., Argentati, C., Franciolini, F., Vassalli, M. , Martino, S. and Catacuzzeno, L. (2022) Piezo1 controls cell volume and migration by modulating swelling-activated chloride current through Ca2+ influx. Journal of Cellular Physiology, 237(3), pp. 1857-1870. (doi: 10.1002/jcp.30656) (PMID:34913176)
Ciccone, G., Azevedo Gonzalez Oliva, M., Antonovaite, N., Lüchtefeld, I., Salmeron-Sanchez, M. and Vassalli, M. (2022) Experimental and data analysis workflow for soft matter nanoindentation. Journal of Visualized Experiments, 179, e63401. (doi: 10.3791/63401)
2021
Gavazzo, P., Viti, F., Donnelly, H. , Oliva, M. A. G., Salmeron-Sanchez, M. , Dalby, M. J. and Vassalli, M. (2021) Biophysical phenotyping of mesenchymal stem cells along the osteogenic differentiation pathway. Cell Biology and Toxicology, 37(6), pp. 915-933. (doi: 10.1007/s10565-020-09569-7) (PMID:33420657)
Yang, B. et al. (2021) Surface-controlled spatially heterogeneous physical properties of a supramolecular gel with homogeneous chemical composition. Chemical Science, 12(42), pp. 14260-14269. (doi: 10.1039/D1SC04671C)
McDowall, D., Walker, M. , Vassalli, M. , Cantini, M. , Khunti, N., Edwards-Gayle, C. J. C., Cowieson, N. and Adams, D. J. (2021) Controlling the formation and alignment of low molecular weight gel ‘noodles’. Chemical Communications, 57(70), pp. 8782-8785. (doi: 10.1039/D1CC03378F) (PMID:34378594)
Dobre, O. et al. (2021) A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors – neural growth and osteogenesis. Advanced Functional Materials, 31(21), 2010225. (doi: 10.1002/adfm.202010225)
Oropesa-Nuñez, R., Mescola, A., Vassalli, M. and Canale, C. (2021) Impact of experimental parameters on cell-cell force spectroscopy signature. Sensors, 21(4), 1069. (doi: 10.3390/s21041069) (PMID:33557265)
Vassalli, M. (2021) Meet the editor series—Massimo Vassalli. Biophysical Reviews, 13, pp. 7-10. (doi: 10.1007/s12551-021-00786-w) (PMID:33747243)
Morales, J. M., Hammarström, B., Lippi, G. L., Vassalli, M. and Glynne-Jones, P. (2021) Acoustofluidic phase microscopy in a tilted segmentation-free configuration. Biomicrofluidics, 15(1), 014102. (doi: 10.1063/5.0036585)
Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)
Obino, D., Vassalli, M. , Franceschi, A., Alessandrini, A., Facci, P. and Viti, F. (2021) An overview on microfluidic systems for nucleic acids extraction from human raw samples. Sensors, 21(9), e3058. (doi: 10.3390/s21093058)
2020
Lüchtefeld, I., Bartolozzi, A., Mejía Morales, J., Dobre, O. , Basso, M., Zambelli, T. and Vassalli, M. (2020) Elasticity spectra as a tool to investigate actin cortex mechanics. Journal of Nanobiotechnology, 18, 147. (doi: 10.1186/s12951-020-00706-2)
Mattarelli, M., Vassalli, M. and Caponi, S. (2020) Relevant length scales in Brillouin imaging of biomaterials: the interplay between phonons propagation and light focalization. ACS Photonics, 7(9), pp. 2319-2328. (doi: 10.1021/acsphotonics.0c00801)
Ciccone, G., Dobre, O. , Gibson, G. M. , Rey, J. M., Gonzalez-Garcia, C., Vassalli, M. , Salmeron-Sanchez, M. and Tassieri, M. (2020) What caging force cells feel in 3D hydrogels: a rheological perspective. Advanced Healthcare Materials, 9(17), 2000517. (doi: 10.1002/adhm.202000517) (PMID:32696605)
Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
Bartolozzi, A., Viti, F., De Stefano, S., Sbrana, F., Petecchia, L., Gavazzo, P. and Vassalli, M. (2020) Development of label-free biophysical markers in osteogenic maturation. Journal of the Mechanical Behavior of Biomedical Materials, 103, 103581. (doi: 10.1016/j.jmbbm.2019.103581)
Gambardella, C., Piazza, V., Vassalli, M. , Sbrana, F., Lavorano, S., Garaventa, F. and Faimali, M. (2020) Microplastics ingestion in the ephyra stage of Aurelia sp. triggers acute and behavioral responses. Ecotoxicology and Environmental Safety, 189, 109983. (doi: 10.1016/j.ecoenv.2019.109983)
Hammarström, B., Vassalli, M. and Glynne-Jones, P. (2020) Acoustic focussing for sedimentation-free high-throughput imaging of microalgae. Journal of Applied Phycology, 32, pp. 339-347. (doi: 10.1007/s10811-019-01907-5)
Ridone, P., Pandzic, E., Vassalli, M. , Cox, C. D., Macmillan, A., Gottlieb, P. A. and Martinac, B. (2020) Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters. Journal of General Physiology, 152(8), e201912515. (doi: 10.1085/jgp.201912515) (PMID:32582958)
2019
Alfieri, R., Vassalli, M. and Viti, F. (2019) Flow-induced mechanotransduction in skeletal cells. Biophysical Reviews, 11(5), pp. 729-743. (doi: 10.1007/s12551-019-00596-1) (PMID:31529361)
Ferrari, A., Capitanio, M., Vassalli, M. and Martinac, B. (2019) Science by the sea: how nanoengineering met mechanobiology in Camogli. Biophysical Reviews, 11(5), pp. 659-661. (doi: 10.1007/s12551-019-00598-z) (PMID:31529357)
Baldini, F., Bartolozzi, A., Ardito, M., Voci, A., Portincasa, P., Vassalli, M. and Vergani, L. (2019) Biomechanics of cultured hepatic cells during different steatogenic hits. Journal of the Mechanical Behavior of Biomedical Materials, 97, pp. 296-305. (doi: 10.1016/j.jmbbm.2019.05.036) (PMID:31151002)
Caponi, S., Canale, C., Cavalleri, O. and Vassalli, M. (2019) Characterization tools for mechanical probing of biomimetic materials. In: Kumar, Challa S.S.R. (ed.) Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy. Springer, pp. 69-111. ISBN 9783662595954 (doi: 10.1007/978-3-662-59596-1_2)
Margheri, G., Tiribilli, B., Trigari, S. and Vassalli, M. (2019) Switchable lensed linear micro axicon in plasmonic structures for all optical light processing. IEEE Photonics Technology Letters, 31(18), pp. 1518-1521. (doi: 10.1109/LPT.2019.2934583)
2018
Cacace, T., Bianco, V., Paturzo, M., Memmolo, P., Vassalli, M. , Fraldi, M., Mensitieri, G. and Ferraro, P. (2018) Retrieving acoustic energy densities and local pressure amplitudes in microfluidics by holographic time-lapse imaging. Lab on a Chip, 18(13), pp. 1921-1927. (doi: 10.1039/C8LC00149A) (PMID:29878010)
Vitale, R. M. et al. (2018) In silico identification and experimental validation of novel anti-Alzheimer’s multitargeted ligands from a marine source featuring a “2-aminoimidazole plus aromatic group” scaffold. ACS Chemical Neuroscience, 9(6), pp. 1290-1303. (doi: 10.1021/acschemneuro.7b00416)
Bloise, N. et al. (2018) The effect of pulsed electromagnetic field exposure on osteoinduction of human mesenchymal stem cells cultured on nano-TiO2 surfaces. PLoS ONE, 13(6), e0199046. (doi: 10.1371/journal.pone.0199046) (PMID:29902240) (PMCID:PMC6002089)
Vassalli, M. et al. (2018) Intercalibration of counting methods for Ostreopsis spp. blooms in the Mediterranean Sea. Ecological Indicators, 85, pp. 1092-1100. (doi: 10.1016/j.ecolind.2017.07.063)
2017
Alloisio, S. et al. (2017) Generation of a functional human neural network by NDM29 overexpression in neuroblastoma cancer cells. Molecular Neurobiology, 54(8), pp. 6097-6106. (doi: 10.1007/s12035-016-0161-3) (PMID:27699601)
Gavazzo, P., Petecchia, L., Facci, P., Vassalli, M. and Viti, F. (2017) Controlled single-cell cyclic compression and transcription analysis: a pilot study. Biophysical Chemistry, 229, pp. 39-45. (doi: 10.1016/j.bpc.2017.07.010) (PMID:28818313)
Petecchia, L., Viti, F., Sbrana, F., Vassalli, M. and Gavazzo, P. (2017) A biophysical approach to quantify skeletal stem cells trans-differentiation as a model for the study of osteoporosis. Biophysical Chemistry, 229, pp. 84-92. (doi: 10.1016/j.bpc.2017.05.011) (PMID:28578832)
Petecchia, L., Usai, C., Vassalli, M. and Gavazzo, P. (2017) Biophysical characterization of nanostructured TiO2 as a good substrate for hBM-MSC adhesion, growth and differentiation. Experimental Cell Research, 358(2), pp. 111-119. (doi: 10.1016/j.yexcr.2017.06.008) (PMID:28619648)
Palazzolo, G., Moroni, M., Soloperto, A., Aletti, G., Naldi, G., Vassalli, M. , Nieus, T. and Difato, F. (2017) Fast wide-volume functional imaging of engineered in vitro brain tissues. Scientific Reports, 7, 8499. (doi: 10.1038/s41598-017-08979-8) (PMID:28819205) (PMCID:PMC5561227)
Cacace, T., Paturzo, M., Memmolo, P., Vassalli, M. , Ferraro, P., Fraldi, M. and Mensitieri, G. (2017) Digital holography as 3D tracking tool for assessing acoustophoretic particle manipulation. Optics Express, 25(15), pp. 17746-17752. (doi: 10.1364/OE.25.017746) (PMID:28789266)
Cacace, T., Paturzo, M., Memmolo, P., Vassalli, M. , Fraldi, M., Mensitieri, G. and Ferraro, P. (2017) Investigation on Microfluidic Particles Manipulation by Holographic 3D Tracking Strategies. In: SPIE Optical Metrology, Munich, Germany, 24-27 Jun 2019, (doi: 10.1117/12.2271829)
Sbrana, F., Landini, E., Gjeci, N., Viti, F., Ottoviani, E. and Vassalli, M. (2017) OvMeter: an automated 3D-integrated opto-electronic system for Ostreopsis cf. ovata bloom monitoring. Journal of Applied Phycology, 29(3), pp. 1363-1375. (doi: 10.1007/s10811-017-1069-7)
2016
Bregante, M., Carpaneto, A., Piazza, V., Sbrana, F., Vassalli, M. , Faimali, M. and Gambale, F. (2016) Osmoregulated chloride currents in hemocytes from mytilus galloprovincialis. PLoS ONE, 11(12), e0167972. (doi: 10.1371/journal.pone.0167972) (PMID:27936151) (PMCID:PMC5148081)
Ghisellini, P., Caiazzo, M., Alessandrini, A., Eggenhöffner, R., Vassalli, M. and Facci, P. (2016) Direct electrical control of IgG conformation and functional activity at surfaces. Scientific Reports, 6, 37779. (doi: 10.1038/srep37779) (PMID:27883075) (PMCID:PMC5121884)
Ossola, D., Dorig, P., Voros, J., Zambelli, T. and Vassalli, M. (2016) Serial weighting of micro-objects with resonant microchanneled cantilevers. Nanotechnology, 27(41), 415502. (doi: 10.1088/0957-4484/27/41/415502) (PMID:27608651)
Coluccino, L., Stagnaro, P., Vassalli, M. and Scaglione, S. (2016) Bioactive TGF-beta 1/HA alginate-based scaffolds for osteochondral tissue repair: design, realization and multilevel characterization. Journal of Applied Biomaterials and Functional Materials, 14(1), e42-e52. (doi: 10.5301/jabfm.5000249) (PMID:26743836)
Soloperto, A., Palazzolo, G., Tsushima, H., Chieregatti, E., Vassalli, M. and Difato, F. (2016) Laser nano-neurosurgery from gentle manipulation to nano-incision of neuronal cells and scaffolds: an advanced neurotechnology tool. Frontiers in Neuroscience, 10, 101. (doi: 10.3389/fnins.2016.00101) (PMID:27013962) (PMCID:PMC4786546)
Soloperto, A., Bartolozzi, A., Palazzolo, G., Basso, M., Contestabile, A., Vassalli, M. and Difato, F. (2016) Expression and Biophysical Characterization of Bacterial Mechano-Sensitive Ion Channel of Large Conductance into Mammalian Cells. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, USA, 27 Feb - 02 Mar 2016.
Soattin, L., Fiore, M., Gavazzo, P., Viti, F., Facci, P., Raiteri, R., Difato, F., Pusch, M. and Vassalli, M. (2016) The biophysics of piezo1 and piezo2 mechanosensitive channels. Biophysical Chemistry, 208, pp. 26-33. (doi: 10.1016/j.bpc.2015.06.013) (PMID:26259784)
Cipolla, L., Russo, L., Sgambato, A., Guizzardi, R., Lecchi, M., Pastori, V., Petecchia, L., Gavazzo, P. and Vassalli, M. (2016) Effects of neoglycosylated collagen matrices on neuroblastoma and human stem cells: a new perspective for neuro-regeneration? Second International Meeting of the Milan Center for Neuroscience (Neuromi): Prediction and Prevention of Dementia: New Hope, Milan, Italy, 06-08 Jul 2016.
2015
Petecchia, L., Sbrana, F., Utzeri, R., Vercellino, M., Usai, C., Visai, L., Vassalli, M. and Gavazzo, P. (2015) Electro-magnetic field promotes osteogenic differentiation of BM-hMSCs through a selective action on Ca(2+)-related mechanisms. Scientific Reports, 5, 13856. (doi: 10.1038/srep13856) (PMID:26364969) (PMCID:PMC4568470)
Tsushima, H., Emanuele, M., Polenghi, A., Esposito, A., Vassalli, M. , Barberis, A., Difato, F. and Chieregatti, E. (2015) HDAC6 and RhoA are novel players in Abeta-driven disruption of neuronal polarity. Nature Communications, 6, 7781. (doi: 10.1038/ncomms8781) (PMID:26198811)
Giussani, V. et al. (2015) Active role of the mucilage in the toxicity mechanism of the harmful benthic dinoflagellate Ostreopsis cf. ovata. Harmful Algae, 44, pp. 46-53. (doi: 10.1016/j.hal.2015.02.006)
Di Poto, A. et al. (2015) In vitro effect of temperature on the conformational structure and collagen binding of SdrF, a Staphylococcus epidermidis adhesin. Applied Microbiology and Biotechnology, 99, s5593-5603. (doi: 10.1007/s00253-015-6456-x) (PMID:25683665)
Asnaghi, V. et al. (2015) Risk-monitoring, Modelling and Mitigation (M3-HABs) of Benthic Microalgal Blooms across Mediterranean Region. Sixth European Phycological Congress, London, UK, 23-28 Aug 2015.
Randazzo, L.A., Santangelo, M.G., Noto, R., Vassalli, M. , Manno, M. and Martorana, V. (2015) Protein Diffusion, Stability and Activity in Crowded Media. 10th European-Biophysical-Societies-Association (EBSA) European Biophysics Congress, Dresden, Germany, 18-22 Jul 2015.
2014
Pastorino, L., Dellacasa, E., Scaglione, S., Giulianelli, M., Sbrana, F., Vassalli, M. and Ruggiero, C. (2014) Oriented collagen nanocoatings for tissue engineering. Colloids and Surfaces B: Biointerfaces, 114, pp. 372-378. (doi: 10.1016/j.colsurfb.2013.10.026) (PMID:24246194)
Barenghi, R., Beke, S., Romano, I., Gavazzo, P., Farkas, B., Vassalli, M. , Brandi, F. and Scaglione, S. (2014) Elastin-coated biodegradable photopolymer scaffolds for tissue engineering applications. BioMed Research International, 2014, 624645. (doi: 10.1155/2014/624645) (PMID:25405204) (PMCID:PMC4227440)
Corsaro, A., Raccosta, S., De Stefano, S., Thellung, S., Villa, V., Manno, M., Martorana, V., Vassalli, M. and Florio, T. (2014) Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements. International Prion Congress, Trieste, Italy, 27-30 May 2014.
2013
Vassalli, M. , Sbrana, F., Laurita, A., Papi, M., Bloise, N., Visai, L. and Bochicchio, B. (2013) Biological and structural characterization of a naturally inspired material engineered from elastin as a candidate for tissue engineering applications. Langmuir, 29(51), pp. 15898-15906. (doi: 10.1021/la403311x) (PMID:24328291)
Torre, B., Basso, M., Tiribilli, B., Paoletti, P. and Vassalli, M. (2013) Disclosing and overcoming the trade-off between noise and scanning speed in atomic force microscopy. Nanotechnology, 24(32), 325104. (doi: 10.1088/0957-4484/24/32/325104) (PMID:23868095)
Petecchia, L., Vercellino, M., Visai, L., Usai, C., Sbrana, F., Vassalli, M. and Gavazzo, P. (2013) Biophysical characterization of human mesenchimal stem cells. European Biophysics Journal with Biophysics Letters, 42(S1), S51. (doi: 10.1007/s00249-013-0917-x)
Vassalli, M. , Basso, M. and Difato, F. (2013) Measurement of tension release during laser induced axon lesion to evaluate axonal adhesion to the substrate at piconewton and millisecond resolution. Journal of Visualized Experiments, 75, e50477. (doi: 10.3791/50477) (PMID:23748878) (PMCID:PMC3720120)
Thellung, S., Gatta, E., Pellistri, F., Corsaro, A., Villa, V., Vassalli, M. , Robello, M. and Florio, T. (2013) Excitotoxicity through NMDA receptors mediates cerebellar granule neuron apoptosis induced by prion protein 90-231 fragment. Neurotoxicity Research, 23, pp. 301-314. (doi: 10.1007/s12640-012-9340-9) (PMID:22855343)
Chiarpotto, M. et al. (2013) Mechanism of aluminium bio-mineralization in the apoferritin cavity. Applied Physics Letters, 103(8), 083701. (doi: 10.1063/1.4818749)
Fanelli, D., McKane, A.J., Pompili, G., Tiribilli, B., Vassalli, M. and Biancalani, T. (2013) Diffusion of two molecular species in a crowded environment: theory and experiments. Physical Biology, 10(4), 045008. (doi: 10.1088/1478-3975/10/4/045008) (PMID:23912053)
Gavazzo, P., Vassalli, M. , Costa, D. and Pagano, A. (2013) Novel ncRNAs transcribed by Pol III and elucidation of their functional relevance by biophysical approaches. Frontiers in Cellular Neuroscience, 7, 203. (doi: 10.3389/fncel.2013.00203)
Greco, G., Svaldo Lanero, T., Torrassa, S., Young, R., Vassalli, M. , Cavaliere, A., Rolandi, R., Pelucchi, E., Faimali, M. and Davenport, J. (2013) Microtopography of the eye surface of the crab Carcinus maenas: an atomic force microscope study suggesting a possible antifouling potential. Journal of the Royal Society: Interface, 10, 20130122. (doi: 10.1098/rsif.2013.0122)
Marasini, C., Jacchetti, E., Moretti, M., Canale, C., Moran, O. and Vassalli, M. (2013) Visualization of single proteins from stripped native cell membranes: a protocol for high-resolution atomic force microscopy. Microscopy Research and Technique, 76(7), pp. 723-732. (doi: 10.1002/jemt.22223) (PMID:23681761)
Scaglione, S., Barenghi, R., Beke, S., Ceseracciu, L., Romano, I., Sbrana, F., Stagnaro, P., Brandi, F. and Vassalli, M. (2013) Characterization of a Bioinspired Elastin-Polypropylene Fumarate Material for Vascular Prostheses Applications. In: SPIE Optical Metrology 2013, Munich, Germany, 13-16 May 2013, 87920H. (doi: 10.1117/12.2021754)
2012
Difato, F., Tsushima, H., Pesce, M., Guiggiani, A., Benfenati, F., Blau, A., Basso, M., Vassalli, M. and Chieregatti, E. (2012) Axonal Regeneration of Cultured Mouse Hippocampal Neurons Studied by an Optical Nano-surgery System. In: SPIE BiOS 2012, San Francisco, CA, USA, 21-26 Jan 2012, p. 820760. (doi: 10.1117/12.908345)
Galante, D., Corsaro, A., Florio, T., Vella, S., Pagano, A., Sbrana, F., Vassalli, M. , Perico, A. and D'Arrigo, C. (2012) Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids. International Journal of Biochemistry and Cell Biology, 44(11), pp. 2085-2093. (doi: 10.1016/j.biocel.2012.08.010)
Mescola, A., Vella, S., Scotto, M., Gavazzo, P., Canale, C., Diaspro, A., Pagano, A. and Vassalli, M. (2012) Probing cytoskeleton organisation of neuroblastoma cells with single-cell force spectroscopy. Journal of Molecular Recognition, 25(5), pp. 270-277. (doi: 10.1002/jmr.2173) (PMID:22528188)
Sbrana, F., Fotia, C., Bracalello, A., Baldini, N., Marletta, G., Ciapetti, G., Bochicchio, B. and Vassalli, M. (2012) Multiscale characterization of a chimeric biomimetic polypeptide for stem cell culture. Bioinspiration and Biomimetics, 7(4), 046007. (doi: 10.1088/1748-3182/7/4/046007)
2011
Basso, M., Paoletti, P., Tiribilli, B. and Vassalli, M. (2011) AFM imaging via nonlinear control of self-driven cantilever oscillations. IEEE Transactions on Nanotechnology, 10(3), pp. 560-565. (doi: 10.1109/TNANO.2010.2051815)
Bracalello, A., Santopietro, V., Vassalli, M. , Marletta, G., Del Gaudio, R., Bochicchio, B. and Pepe, A. (2011) Design and production of a chimeric resilin-, elastin-, and collagen-like engineered polypeptide. Biomacromolecules, 12(8), pp. 2957-2965. (doi: 10.1021/bm2005388) (PMID:21707089)
Guiggiani, A., Torre, B., Contestabile, A., Benfenati, F., Basso, M., Vassalli, M. and Difato, F. (2011) Long-range and long-term interferometric tracking by static and dynamic force-clamp optical tweezers. Optics Express, 19(23), pp. 22364-22376. (doi: 10.1364/OE.19.022364)
Marasini, C. and Vassalli, M. (2011) Direct Visualization of CFTR Conformation by Atomic Force Microscopy Imaging. 8th EBSA European Biophysics Congress, Budapest, Hungary, 23-27 Aug 2011.
Marchetti, S., Sbrana, F., Toscano, A., Fratini, E., Carlà, M., Vassalli, M. , Tiribilli, B., Pacini, A. and Gambi, C.M.C. (2011) β-connectin studies by small-angle x-ray scattering and single-molecule force spectroscopy by atomic force microscopy. Physical Review E, 83, 051919. (doi: 10.1103/PhysRevE.83.051919) (PMID:21728583)
Paoletti, P., Basso, M., Pini, V., Tiribilli, B. and Vassalli, M. (2011) Self-driven soft imaging in liquid by means of photothermal excitation. Journal of Applied Physics, 110, 114315. (doi: 10.1063/1.3665396)
Pini, V., Tiribilli, B., Gambi, C. M. C. and Vassalli, M. (2011) Erratum: Dynamical characterization of vibrating AFM cantilevers forced by photothermal excitation (vol 81, 054302, 2010). Physical Review B, 83, 179904. (doi: 10.1103/PhysRevB.83.179904)
Sbrana, F., Lorusso, M., Canale, C., Bochicchio, B. and Vassalli, M. (2011) Effect of chemical cross-linking on the mechanical properties of elastomeric peptides studied by single molecule force spectroscopy. Journal of Biomechanics, 44(11), pp. 2118-2122. (doi: 10.1016/j.jbiomech.2011.05.028)
2010
Monaldi, I., Vassalli, M. , Bachi, A., Giovedi, S., Millo, E., Valtorta, F., Raiteri, R., Benfenati, F. and Fassio, A. (2010) The highly conserved synapsin domain E mediates synapsin dimerization and phospholipid vesicle clustering. Biochemical Journal, 426(1), pp. 55-64. (doi: 10.1042/BJ20090762) (PMID:19922412)
Pini, V., Tiribilli, B., Gambi, C. M. C. and Vassalli, M. (2010) Dynamical characterization of vibrating AFM cantilevers forced by photothermal excitation. Physical Review B, 81, 054302. (doi: 10.1103/PhysRevB.81.054302)
Sbrana, F., Fanelli, D., Vassalli, M. , Carresi, L., Scala, A., Pazzagli, L., Cappugi, G. and Tiribilli, B. (2010) Progressive pearl necklace collapse mechanism for cerato-ulmin aggregation film. European Biophysics Journal with Biophysics Letters, 39, pp. 971-977. (doi: 10.1007/s00249-009-0465-6) (PMID:19471919)
Vassalli, M. , Pini, V. and Tiribilli, B. (2010) Role of the driving laser position on atomic force microscopy cantilevers excited by photothermal and radiation pressure effects. Applied Physics Letters, 97, 143105. (doi: 10.1063/1.3497074)
2009
Basso, M., Paoletti, P., Tiribilli, B. and Vassalli, M. (2009) Modeling and Analysis of Auto-tapping AFM. In: 47th IEEE Conference on Decision and Control, Cancun, Mexico, 09-11 Dec 2008, pp. 5188-5193. ISBN 9781424431236 (doi: 10.1109/CDC.2008.4739214)
2008
Basso, M., Paoletti, P., Tiribilli, B. and Vassalli, M. (2008) Modelling and analysis of autonomous micro-cantilever oscillations. Nanotechnology, 19(47), 475501. (doi: 10.1088/0957-4484/19/47/475501)
Becucci, L., Innocenti, M., Salvietti, E., Rindi, A., Pasquini, I., Vassalli, M. , Foresti, M. L. and Guidelli, R. (2008) Potassium ion transport by gramicidin and valinomycin across a Ag(111)-supported tethered bilayer lipid membrane. Electrochimica Acta, 53(22), pp. 6372-6379. (doi: 10.1016/j.electacta.2008.04.043)
Imparato, A., Sbrana, F. and Vassalli, M. (2008) Reconstructing the free-energy landscape of a polyprotein by single-molecule experiments. EPL (Europhysics Letters), 82(5), 58006. (doi: 10.1209/0295-5075/82/58006)
Marchetti, S., Sbrana, F., Raccis, R., Lanzi, L., Gambi, C.M.C., Vassalli, M. , Tiribilli, B., Pacini, A. and Toscano, A. (2008) Dynamic light scattering and atomic force microscopy imaging on fragments of beta-connectin from human cardiac muscle. Physical Review E, 77, 021910. (doi: 10.1103/PhysRevE.77.021910)
Papi, M., Maulucci, G., Arcovito, G., Paoletti, P., Vassalli, M. and De Spirito, M. (2008) Detection of microviscosity by using uncalibrated atomic force microscopy cantilevers. Applied Physics Letters, 93, 124102. (doi: 10.1063/1.2970963)
2007
Sbrana, F., Bongini, L., Cappugi, G., Fanelli, D., Guarino, A., Pazzagli, L., Scala, A., Vassalli, M. , Zoppi, C. and Tiribilli, B. (2007) Atomic force microscopy images suggest aggregation mechanism in cerato-platanin. European Biophysics Journal with Biophysics Letters, 36, pp. 727-732. (doi: 10.1007/s00249-007-0159-x)
2006
Basso, M., Bucher, R., Romagnoli, M. and Vassalli, M. (2006) Real-time Lontrol with Linux: A Web Services Approach. In: 44th IEEE Conference on Decision and Control, 2005 and 2005 European Control Conference. CDC-ECC '05., Seville, Spain, 12-15 December 2005, pp. 2733-2738. ISBN 0780395670 (doi: 10.1109/CDC.2005.1582576)
Giannini, R., Vassalli, M. , Chellini, F., Polidori, L., Dei, R. and Giannelli, M. (2006) Neodymium:yttrium aluminum garnet laser irradiation with low pulse energy: a potential tool for the treatment of peri-implant disease. Clinical Oral Implants Research, 17(6), pp. 638-643. (doi: 10.1111/j.1600-0501.2006.01278.x) (PMID:17092221)
Papi, M., Arcovito, G., De Spirito, M., Vassalli, M. and Tiribilli, B. (2006) Fluid viscosity determination by means of uncalibrated atomic force microscopy cantilevers. Applied Physics Letters, 88, 194102. (doi: 10.1063/1.2200588)
Quercioli, F., Tiribilli, B., Vassalli, M. and Sbrana, F. (2006) Autocorrelator designs for nonlinear optical microscopy. Optical Engineering, 45(6), 064303. (doi: 10.1117/1.2215379)
Tiribilli, B., Ferraro, P., Grilli, S., Molesini, G., Vannoni, M. and Vassalli, M. (2006) An Integrated Approach for Photonic Crystal Inspection and Characterization. In: SPIE Photonics Europe, Strasbourg, France, 03-07 Apr 2006, 61880A. (doi: 10.1117/12.664930)
2005
Grilli, S., Ferraro, P., De Natale, P., Tiribilli, B. and Vassalli, M. (2005) Surface nanoscale periodic structures in congruent lithium niobate by domain reversal patterning and differential etching. Applied Physics Letters, 87(23), 233106. (doi: 10.1063/1.2137877)
Grilli, S., Ferraro, P., Sansone, L., Tiribilli, B., Vassalli, M. and De Natale, P. (2005) Fabrication of 2D Sub-micron Structures in Lithium Niobate for Photonic Crystal Applications. In: Optics and Photonics 2005, San Diego, CA, USA, 31 Jul - 04 Aug 2005, p. 593107. (doi: 10.1117/12.617106)
Tiribilli, B., Bani, D., Quercioli, F., Ghirelli, A. and Vassalli, M. (2005) Atomic force microscopy of histological sections using a chemical etching method. Ultramicroscopy, 102(3), pp. 227-232. (doi: 10.1016/j.ultramic.2004.10.003) (PMID:15639354)
2004
Quercioli, F., Tiribilli, B. and Vassalli, M. (2004) Wavefront-division lateral shearing autocorrelator for ultrafast laser microscopy. Optics Express, 12(18), pp. 4303-4312. (doi: 10.1364/OPEX.12.004303) (PMID:19483977)
Quercioli, F., Tiribilli, B., Vassalli, M. and Ghirelli, A. (2004) Laser spectral characterization in multiphoton microscopy. Applied Optics, 43(15), pp. 3055-3060. (doi: 10.1364/AO.43.003055) (PMID:15176192)
Formigli, L. et al. (2004) Sphingosine 1-phosphate induces cell contraction via calcium-independent/Rho-dependent pathways in undifferentiated skeletal muscle cells. Journal of Cellular Physiology, 198(1), pp. 1-11. (doi: 10.1002/jcp.10366) (PMID:14584038)
Nosi, D., Vassalli, M. , Polidori, L., Giannini, R., Tani, A., Chellini, F. and Paternostro, F. (2004) Effects of S1P on myoblastic cell contraction: Possible involvement of Ca2+-independent mechanisms. Cells Tissues Organs, 178(3), pp. 129-138. (doi: 10.1159/000082243) (PMID:15655330)
Pelli, S., Righini, G.C., Quercioli, F., Tiribilli, B., Vassalli, M. , Cremona, M. and Pereira, J.A.M. (2004) Optical Waveguides in LiF by Ion-beam Irradiation: Fabrication and Characterisation. In: 2003 Conference on Lasers and Electro-Optics Europe (CLEO/Europe 2003), Munich, Germany, 22-27 Jun 2003, p. 682. ISBN 0780377346 (doi: 10.1109/CLEOE.2003.1313740)
Quercioli, F., Ghirelli, A., Tiribilli, B. and Vassalli, M. (2004) Ultracompact autocorrelator for multiphoton microscopy. Microscopy Research and Technique, 63(1), pp. 27-33. (doi: 10.1002/jemt.10420) (PMID:14677131)
Quercioli, F., Ghirelli, A., Tiribilli, B. and Vassalli, M. (2004) Autocorrelator for Multiphoton Microscopy. In: Photonics Europe, Strasbourg, France, 2004, pp. 162-170. (doi: 10.1117/12.544609)
2003
Bencini, C. et al. (2003) Effects of sphingosine 1-phosphate on excitation–contraction coupling in mammalian skeletal muscle. Journal of Muscle Research and Cell Motility, 24(8), pp. 539-554. (doi: 10.1023/B:JURE.0000009898.02325.58) (PMID:14870969)
Vassalli, M. and Giannelli, M. (2003) Effect of Nd: YAG laser on titanium dental implants studied by AFM. Italian Journal of Anatomy and Embryology, 108(4), pp. 195-203. (PMID:14974502)
Buah-Bassuah, P. K., Tiribilli, B., Vassalli, M. and Molesini, G. (2003) Simple portable lens meter. Applied Optics, 42(25), pp. 5086-5090. (doi: 10.1364/AO.42.005086) (PMID:12962384)
Pelli, S., Brenci, M., Calzolai, R., Quercioli, F., Tiribilli, B., Vassalli, M. , Ghirelli, A., Cremona, M., Pereira, J.A.M. and Righini, G.C. (2003) Confocal Luminescence Microscopy Characterization of Optical Waveguides Produced by Ion Beam Irradiation on LiF. In: Integrated Optoelectronics Devices, San Jose, CA, USA, 2003, pp. 13-20. (doi: 10.1117/12.478329)
Quercioli, F., Tiribilli, B., Vassalli, M. , Ghirelli, A., Righini, G., Pelli, S. and Cremona, M. (2003) Confocal Microscopy for the Testing of Integrated Optical Devices. In: 19th Congress of the International Commission for Optics: Optics for the Quality of Life, Florence, Italy, 2002, pp. 665-667. (doi: 10.1117/12.527040)
2002
Formigli, L. et al. (2002) Sphingosine 1-phosphate induces Ca2+ transients and cytoskeletal rearrangement in C2C12 myoblastic cells. American Journal of Physiology: Cell Physiology, 282(6), C1361-C1373. (doi: 10.1152/ajpcell.00378.2001) (PMID:11997251)
Francini, F. et al. (2002) Ca2+ homeostasis and cytoskeletal rearrangement operated by sphingosine 1-phosphate in C2C12 myoblastic cells. Journal of Gravitational Physiology, 9(1), P281-P282. (PMID:15002581)
2001
Bartoli, A., Poggi, P., Quercioli, F., Tiribilli, B. and Vassalli, M. (2001) Optical profilometer with a standalone scanning sensor head. Optical Engineering, 40(12), pp. 2852-2859. (doi: 10.1117/1.1417494)
2000
Giacomelli, G., Hegger, R., Politi, A. and Vassalli, M. (2000) Convective Lyapunov exponents and propagation of correlations. Physical Review Letters, 85(17), 3616. (doi: 10.1103/PhysRevLett.85.3616)
Giardinà, C., Livi, R., Politi, A. and Vassalli, M. (2000) Finite thermal conductivity in 1D lattices. Physical Review Letters, 84(10), 2144. (doi: 10.1103/PhysRevLett.84.2144)
Articles
Binner, P. , Starshynov, I. , Tejeda, G. , McFall, A. , Molloy, C. , Ciccone, G., Walker, M. , Vassalli, M. , Tobin, A. B. and Faccio, D. (2025) Optical, contact-free assessment of brain tissue stiffness and neurodegeneration. Biomedical Optics Express, 16(2), pp. 447-459. (doi: 10.1364/BOE.545580)
Ciccone, G., Azevedo Gonzalez Oliva, M., Versaevel, M., Cantini, M. , Vassalli, M. , Salmeron-Sanchez, M. and Gabriele, S. (2025) Epithelial cell mechanoresponse to matrix viscoelasticity and confinement within micropatterned viscoelastic hydrogels. Advanced Science, (Accepted for Publication)
Gelli, M., Tiribilli, B., Salam, F. A., Vassalli, M. and Basso, M. (2025) Adaptive drive as a control strategy for fast scanning in dynamic mode atomic force microscopy. Sensors, 25(3), 860. (doi: 10.3390/s25030860)
Tan, M. et al. (2024) Polyetherureas as aqueous binders for Li ion batteries. ChemRxiv, (doi: 10.26434/chemrxiv-2024-mk39b)
Cubero-Sarabia, M., Kapetanaki, A. M. and Vassalli, M. (2024) Biophysical assays to test cellular mechanosensing: moving towards high throughput. Biophysical Reviews, (Accepted for Publication)
Cubero-Sarabia, M., Kapetanaki, A. M. and Vassalli, M. (2024) Biophysical assays to test cellular mechanosensing: moving towards high throughput. Biophysical Reviews, 16(6), pp. 875-882. (doi: 10.1007/s12551-024-01263-w) (PMID:39830126) (PMCID:PMC11735701)
Giampietro, C., Ferrari, A. and Vassalli, M. (2024) Editorial to the topical issue: the 7th Nanoengineering for Mechanobiology Symposium 2024 Camogli, Genoa, Italy. Biophysical Reviews, 16(6), pp. 831-832. (doi: 10.1007/s12551-024-01262-x) (PMID:39830131)
Kulyabin, P., Magdysyuk, O. V., Naden, A. B., McLean Dawson, D., Pancholi, K., Walker, M. , Vassalli, M. and Kumar, A. (2024) Manganese-catalyzed synthesis of polyketones using hydrogen-borrowing approach. ACS Catalysis, 14, pp. 10624-10634. (doi: 10.1021/acscatal.4c03019) (Early Online Publication)
Morena, F., Argentati, C., Caponi, S., Lüchtefeld, I., Emiliani, C., Vassalli, M. and Martino, S. (2024) Piezo1 – serine/threonine-protein phosphatase 2A – Cofilin1 biochemical mechanotransduction axis controls F-actin dynamics and cell migration. Heliyon, 10(11), e32458. (doi: 10.1016/j.heliyon.2024.e32458) (PMID:38933959) (PMCID:PMC11201121)
Lüchtefeld, I. et al. (2024) Dissecting cell membrane tension dynamics and its effect on Piezo1-mediated cellular mechanosensitivity using force-controlled nanopipettes. Nature Methods, 21(6), pp. 1063-1073. (doi: 10.1038/s41592-024-02277-8) (PMID:38802520)
Ghosh, D. , Coulter, S. M., Laverty, G., Holland, C., Doutch, J. J., Vassalli, M. and Adams, D. J. (2024) Metal cross-linked supramolecular gel noodles: structural insights and antibacterial assessment. Biomacromolecules, 25(5), pp. 3169-3177. (doi: 10.1021/acs.biomac.4c00300) (PMID:38684138) (PMCID:PMC11094724)
Giampietro, C., Ferrari, A. and Vassalli, M. (2024) Biophysical Reviews’ topical issue: the 7th Nanoengineering for Mechanobiology Symposium 2024 Camogli, Genoa, Italy. Biophysical Reviews, 16(2), pp. 149-150. (doi: 10.1007/s12551-024-01193-7) (PMID:38737207) (PMCID:PMC11078896)
Bonnefond, S., Reynaud, A., Cazareth, J., Abélanet, S., Vassalli, M. , Brau, F. and Lippi, G. L. (2023) Nanoscatterer-assisted fluorescence amplification technique. Nanomaterials, 13(21), 2875. (doi: 10.3390/nano13212875) (PMID:37947721)
Ghosh, D. , Marshall, L. J., Ciccone, G., Liu, W., Squires, A., Seddon, A., Vassalli, M. and Adams, D. J. (2023) Fine-tuning supramolecular assemblies by controlling micellar aggregates. Macromolecular Materials and Engineering, 308(10), 2300082. (doi: 10.1002/mame.202300082)
Viti, F. et al. (2023) Multi-disciplinary insights from the First European Forum on Visceral Myopathy 2022 Meeting. Digestive Diseases and Sciences, 68, pp. 3857-3871. (doi: 10.1007/s10620-023-08066-1) (PMID:37650948) (PMCID:PMC10517037)
Viti, F. et al. (2023) Patient's dermal fibrolasts as disease markers for visceral myopathy. Biomaterials Advances, 148, 213355. (doi: 10.1016/j.bioadv.2023.213355)
Marshall, L. J., Wallace, M., Mahmoudi, N., Ciccone, G., Wilson, C. , Vassalli, M. and Adams, D. J. (2023) Hierarchical composite self-sorted supramolecular gel noodles. Advanced Materials, 35(17), 2211277. (doi: 10.1002/adma.202211277) (PMID:36720202)
Zambito, M., Viti, F., Bosio, A. G., Ceccherini, I., Florio, T. and Vassalli, M. (2023) The impact of experimental conditions on cell mechanics as measured with nanoindentation. Nanomaterials, 13(7), 1190. (doi: 10.3390/nano13071190)
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
Grandy, C., Port, F., Pfeil, J., Azevedo Gonzalez Oliva, M., Vassalli, M. and Gottschalk, K.-E. (2023) Cell shape and tension alter focal adhesion structure. Biomaterials Advances, 145, 213277. (doi: 10.1016/j.bioadv.2022.213277)
Mouro, J., Paoletti, P., Sartore, M., Vassalli, M. and Tiribilli, B. (2022) Photothermal self-excitation of a phase-controlled microcantilever for viscosity or viscoelasticity sensing. Sensors, 22(21), 8421. (doi: 10.3390/s22218421) (PMID:36366122)
Capponi, G., Zambito, M., Neri, I., Cottone, F., Mattarelli, M., Vassalli, M. , Caponi, S. and Florio, T. (2022) Cellular mechanosensitivity: validation of an adaptable 3d-printed device for microindentation. Nanomaterials, 12(15), 2691. (doi: 10.3390/nano12152691)
Baldini, F., Khalil, M., Bartolozzi, A., Vassalli, M. , Di Ciaula, A., Portincasa, P. and Vergani, L. (2022) Relationship between liver stiffness and steatosis in obesity conditions: in vivo and in vitro studies. Biomolecules, 12(5), 733. (doi: 10.3390/biom12050733)
Caponi, S., Passeri, A., Capponi, G., Fioretto, D., Vassalli, M. and Mattarelli, M. (2022) Non-contact elastography methods in mechanobiology: a point of view. European Biophysics Journal, 51(2), pp. 99-104. (doi: 10.1007/s00249-021-01567-9) (PMID:34463775)
Mejia Morales, J., Glynne-Jones, P., Vassalli, M. and Lippi, G.L. (2022) Acoustofluidic interferometric device for rapid single cell physical phenotyping. European Biophysics Journal, 51(2), pp. 185-191. (doi: 10.1007/s00249-021-01585-7) (PMID:35018482)
Sforna, L., Michelucci, A., Morena, F., Argentati, C., Franciolini, F., Vassalli, M. , Martino, S. and Catacuzzeno, L. (2022) Piezo1 controls cell volume and migration by modulating swelling-activated chloride current through Ca2+ influx. Journal of Cellular Physiology, 237(3), pp. 1857-1870. (doi: 10.1002/jcp.30656) (PMID:34913176)
Ciccone, G., Azevedo Gonzalez Oliva, M., Antonovaite, N., Lüchtefeld, I., Salmeron-Sanchez, M. and Vassalli, M. (2022) Experimental and data analysis workflow for soft matter nanoindentation. Journal of Visualized Experiments, 179, e63401. (doi: 10.3791/63401)
Gavazzo, P., Viti, F., Donnelly, H. , Oliva, M. A. G., Salmeron-Sanchez, M. , Dalby, M. J. and Vassalli, M. (2021) Biophysical phenotyping of mesenchymal stem cells along the osteogenic differentiation pathway. Cell Biology and Toxicology, 37(6), pp. 915-933. (doi: 10.1007/s10565-020-09569-7) (PMID:33420657)
Yang, B. et al. (2021) Surface-controlled spatially heterogeneous physical properties of a supramolecular gel with homogeneous chemical composition. Chemical Science, 12(42), pp. 14260-14269. (doi: 10.1039/D1SC04671C)
McDowall, D., Walker, M. , Vassalli, M. , Cantini, M. , Khunti, N., Edwards-Gayle, C. J. C., Cowieson, N. and Adams, D. J. (2021) Controlling the formation and alignment of low molecular weight gel ‘noodles’. Chemical Communications, 57(70), pp. 8782-8785. (doi: 10.1039/D1CC03378F) (PMID:34378594)
Dobre, O. et al. (2021) A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors – neural growth and osteogenesis. Advanced Functional Materials, 31(21), 2010225. (doi: 10.1002/adfm.202010225)
Oropesa-Nuñez, R., Mescola, A., Vassalli, M. and Canale, C. (2021) Impact of experimental parameters on cell-cell force spectroscopy signature. Sensors, 21(4), 1069. (doi: 10.3390/s21041069) (PMID:33557265)
Vassalli, M. (2021) Meet the editor series—Massimo Vassalli. Biophysical Reviews, 13, pp. 7-10. (doi: 10.1007/s12551-021-00786-w) (PMID:33747243)
Morales, J. M., Hammarström, B., Lippi, G. L., Vassalli, M. and Glynne-Jones, P. (2021) Acoustofluidic phase microscopy in a tilted segmentation-free configuration. Biomicrofluidics, 15(1), 014102. (doi: 10.1063/5.0036585)
Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)
Obino, D., Vassalli, M. , Franceschi, A., Alessandrini, A., Facci, P. and Viti, F. (2021) An overview on microfluidic systems for nucleic acids extraction from human raw samples. Sensors, 21(9), e3058. (doi: 10.3390/s21093058)
Lüchtefeld, I., Bartolozzi, A., Mejía Morales, J., Dobre, O. , Basso, M., Zambelli, T. and Vassalli, M. (2020) Elasticity spectra as a tool to investigate actin cortex mechanics. Journal of Nanobiotechnology, 18, 147. (doi: 10.1186/s12951-020-00706-2)
Mattarelli, M., Vassalli, M. and Caponi, S. (2020) Relevant length scales in Brillouin imaging of biomaterials: the interplay between phonons propagation and light focalization. ACS Photonics, 7(9), pp. 2319-2328. (doi: 10.1021/acsphotonics.0c00801)
Ciccone, G., Dobre, O. , Gibson, G. M. , Rey, J. M., Gonzalez-Garcia, C., Vassalli, M. , Salmeron-Sanchez, M. and Tassieri, M. (2020) What caging force cells feel in 3D hydrogels: a rheological perspective. Advanced Healthcare Materials, 9(17), 2000517. (doi: 10.1002/adhm.202000517) (PMID:32696605)
Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
Bartolozzi, A., Viti, F., De Stefano, S., Sbrana, F., Petecchia, L., Gavazzo, P. and Vassalli, M. (2020) Development of label-free biophysical markers in osteogenic maturation. Journal of the Mechanical Behavior of Biomedical Materials, 103, 103581. (doi: 10.1016/j.jmbbm.2019.103581)
Gambardella, C., Piazza, V., Vassalli, M. , Sbrana, F., Lavorano, S., Garaventa, F. and Faimali, M. (2020) Microplastics ingestion in the ephyra stage of Aurelia sp. triggers acute and behavioral responses. Ecotoxicology and Environmental Safety, 189, 109983. (doi: 10.1016/j.ecoenv.2019.109983)
Hammarström, B., Vassalli, M. and Glynne-Jones, P. (2020) Acoustic focussing for sedimentation-free high-throughput imaging of microalgae. Journal of Applied Phycology, 32, pp. 339-347. (doi: 10.1007/s10811-019-01907-5)
Ridone, P., Pandzic, E., Vassalli, M. , Cox, C. D., Macmillan, A., Gottlieb, P. A. and Martinac, B. (2020) Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters. Journal of General Physiology, 152(8), e201912515. (doi: 10.1085/jgp.201912515) (PMID:32582958)
Alfieri, R., Vassalli, M. and Viti, F. (2019) Flow-induced mechanotransduction in skeletal cells. Biophysical Reviews, 11(5), pp. 729-743. (doi: 10.1007/s12551-019-00596-1) (PMID:31529361)
Ferrari, A., Capitanio, M., Vassalli, M. and Martinac, B. (2019) Science by the sea: how nanoengineering met mechanobiology in Camogli. Biophysical Reviews, 11(5), pp. 659-661. (doi: 10.1007/s12551-019-00598-z) (PMID:31529357)
Baldini, F., Bartolozzi, A., Ardito, M., Voci, A., Portincasa, P., Vassalli, M. and Vergani, L. (2019) Biomechanics of cultured hepatic cells during different steatogenic hits. Journal of the Mechanical Behavior of Biomedical Materials, 97, pp. 296-305. (doi: 10.1016/j.jmbbm.2019.05.036) (PMID:31151002)
Margheri, G., Tiribilli, B., Trigari, S. and Vassalli, M. (2019) Switchable lensed linear micro axicon in plasmonic structures for all optical light processing. IEEE Photonics Technology Letters, 31(18), pp. 1518-1521. (doi: 10.1109/LPT.2019.2934583)
Cacace, T., Bianco, V., Paturzo, M., Memmolo, P., Vassalli, M. , Fraldi, M., Mensitieri, G. and Ferraro, P. (2018) Retrieving acoustic energy densities and local pressure amplitudes in microfluidics by holographic time-lapse imaging. Lab on a Chip, 18(13), pp. 1921-1927. (doi: 10.1039/C8LC00149A) (PMID:29878010)
Vitale, R. M. et al. (2018) In silico identification and experimental validation of novel anti-Alzheimer’s multitargeted ligands from a marine source featuring a “2-aminoimidazole plus aromatic group” scaffold. ACS Chemical Neuroscience, 9(6), pp. 1290-1303. (doi: 10.1021/acschemneuro.7b00416)
Bloise, N. et al. (2018) The effect of pulsed electromagnetic field exposure on osteoinduction of human mesenchymal stem cells cultured on nano-TiO2 surfaces. PLoS ONE, 13(6), e0199046. (doi: 10.1371/journal.pone.0199046) (PMID:29902240) (PMCID:PMC6002089)
Vassalli, M. et al. (2018) Intercalibration of counting methods for Ostreopsis spp. blooms in the Mediterranean Sea. Ecological Indicators, 85, pp. 1092-1100. (doi: 10.1016/j.ecolind.2017.07.063)
Alloisio, S. et al. (2017) Generation of a functional human neural network by NDM29 overexpression in neuroblastoma cancer cells. Molecular Neurobiology, 54(8), pp. 6097-6106. (doi: 10.1007/s12035-016-0161-3) (PMID:27699601)
Gavazzo, P., Petecchia, L., Facci, P., Vassalli, M. and Viti, F. (2017) Controlled single-cell cyclic compression and transcription analysis: a pilot study. Biophysical Chemistry, 229, pp. 39-45. (doi: 10.1016/j.bpc.2017.07.010) (PMID:28818313)
Petecchia, L., Viti, F., Sbrana, F., Vassalli, M. and Gavazzo, P. (2017) A biophysical approach to quantify skeletal stem cells trans-differentiation as a model for the study of osteoporosis. Biophysical Chemistry, 229, pp. 84-92. (doi: 10.1016/j.bpc.2017.05.011) (PMID:28578832)
Petecchia, L., Usai, C., Vassalli, M. and Gavazzo, P. (2017) Biophysical characterization of nanostructured TiO2 as a good substrate for hBM-MSC adhesion, growth and differentiation. Experimental Cell Research, 358(2), pp. 111-119. (doi: 10.1016/j.yexcr.2017.06.008) (PMID:28619648)
Palazzolo, G., Moroni, M., Soloperto, A., Aletti, G., Naldi, G., Vassalli, M. , Nieus, T. and Difato, F. (2017) Fast wide-volume functional imaging of engineered in vitro brain tissues. Scientific Reports, 7, 8499. (doi: 10.1038/s41598-017-08979-8) (PMID:28819205) (PMCID:PMC5561227)
Cacace, T., Paturzo, M., Memmolo, P., Vassalli, M. , Ferraro, P., Fraldi, M. and Mensitieri, G. (2017) Digital holography as 3D tracking tool for assessing acoustophoretic particle manipulation. Optics Express, 25(15), pp. 17746-17752. (doi: 10.1364/OE.25.017746) (PMID:28789266)
Sbrana, F., Landini, E., Gjeci, N., Viti, F., Ottoviani, E. and Vassalli, M. (2017) OvMeter: an automated 3D-integrated opto-electronic system for Ostreopsis cf. ovata bloom monitoring. Journal of Applied Phycology, 29(3), pp. 1363-1375. (doi: 10.1007/s10811-017-1069-7)
Bregante, M., Carpaneto, A., Piazza, V., Sbrana, F., Vassalli, M. , Faimali, M. and Gambale, F. (2016) Osmoregulated chloride currents in hemocytes from mytilus galloprovincialis. PLoS ONE, 11(12), e0167972. (doi: 10.1371/journal.pone.0167972) (PMID:27936151) (PMCID:PMC5148081)
Ghisellini, P., Caiazzo, M., Alessandrini, A., Eggenhöffner, R., Vassalli, M. and Facci, P. (2016) Direct electrical control of IgG conformation and functional activity at surfaces. Scientific Reports, 6, 37779. (doi: 10.1038/srep37779) (PMID:27883075) (PMCID:PMC5121884)
Ossola, D., Dorig, P., Voros, J., Zambelli, T. and Vassalli, M. (2016) Serial weighting of micro-objects with resonant microchanneled cantilevers. Nanotechnology, 27(41), 415502. (doi: 10.1088/0957-4484/27/41/415502) (PMID:27608651)
Coluccino, L., Stagnaro, P., Vassalli, M. and Scaglione, S. (2016) Bioactive TGF-beta 1/HA alginate-based scaffolds for osteochondral tissue repair: design, realization and multilevel characterization. Journal of Applied Biomaterials and Functional Materials, 14(1), e42-e52. (doi: 10.5301/jabfm.5000249) (PMID:26743836)
Soloperto, A., Palazzolo, G., Tsushima, H., Chieregatti, E., Vassalli, M. and Difato, F. (2016) Laser nano-neurosurgery from gentle manipulation to nano-incision of neuronal cells and scaffolds: an advanced neurotechnology tool. Frontiers in Neuroscience, 10, 101. (doi: 10.3389/fnins.2016.00101) (PMID:27013962) (PMCID:PMC4786546)
Soattin, L., Fiore, M., Gavazzo, P., Viti, F., Facci, P., Raiteri, R., Difato, F., Pusch, M. and Vassalli, M. (2016) The biophysics of piezo1 and piezo2 mechanosensitive channels. Biophysical Chemistry, 208, pp. 26-33. (doi: 10.1016/j.bpc.2015.06.013) (PMID:26259784)
Petecchia, L., Sbrana, F., Utzeri, R., Vercellino, M., Usai, C., Visai, L., Vassalli, M. and Gavazzo, P. (2015) Electro-magnetic field promotes osteogenic differentiation of BM-hMSCs through a selective action on Ca(2+)-related mechanisms. Scientific Reports, 5, 13856. (doi: 10.1038/srep13856) (PMID:26364969) (PMCID:PMC4568470)
Tsushima, H., Emanuele, M., Polenghi, A., Esposito, A., Vassalli, M. , Barberis, A., Difato, F. and Chieregatti, E. (2015) HDAC6 and RhoA are novel players in Abeta-driven disruption of neuronal polarity. Nature Communications, 6, 7781. (doi: 10.1038/ncomms8781) (PMID:26198811)
Giussani, V. et al. (2015) Active role of the mucilage in the toxicity mechanism of the harmful benthic dinoflagellate Ostreopsis cf. ovata. Harmful Algae, 44, pp. 46-53. (doi: 10.1016/j.hal.2015.02.006)
Di Poto, A. et al. (2015) In vitro effect of temperature on the conformational structure and collagen binding of SdrF, a Staphylococcus epidermidis adhesin. Applied Microbiology and Biotechnology, 99, s5593-5603. (doi: 10.1007/s00253-015-6456-x) (PMID:25683665)
Pastorino, L., Dellacasa, E., Scaglione, S., Giulianelli, M., Sbrana, F., Vassalli, M. and Ruggiero, C. (2014) Oriented collagen nanocoatings for tissue engineering. Colloids and Surfaces B: Biointerfaces, 114, pp. 372-378. (doi: 10.1016/j.colsurfb.2013.10.026) (PMID:24246194)
Barenghi, R., Beke, S., Romano, I., Gavazzo, P., Farkas, B., Vassalli, M. , Brandi, F. and Scaglione, S. (2014) Elastin-coated biodegradable photopolymer scaffolds for tissue engineering applications. BioMed Research International, 2014, 624645. (doi: 10.1155/2014/624645) (PMID:25405204) (PMCID:PMC4227440)
Vassalli, M. , Sbrana, F., Laurita, A., Papi, M., Bloise, N., Visai, L. and Bochicchio, B. (2013) Biological and structural characterization of a naturally inspired material engineered from elastin as a candidate for tissue engineering applications. Langmuir, 29(51), pp. 15898-15906. (doi: 10.1021/la403311x) (PMID:24328291)
Torre, B., Basso, M., Tiribilli, B., Paoletti, P. and Vassalli, M. (2013) Disclosing and overcoming the trade-off between noise and scanning speed in atomic force microscopy. Nanotechnology, 24(32), 325104. (doi: 10.1088/0957-4484/24/32/325104) (PMID:23868095)
Petecchia, L., Vercellino, M., Visai, L., Usai, C., Sbrana, F., Vassalli, M. and Gavazzo, P. (2013) Biophysical characterization of human mesenchimal stem cells. European Biophysics Journal with Biophysics Letters, 42(S1), S51. (doi: 10.1007/s00249-013-0917-x)
Vassalli, M. , Basso, M. and Difato, F. (2013) Measurement of tension release during laser induced axon lesion to evaluate axonal adhesion to the substrate at piconewton and millisecond resolution. Journal of Visualized Experiments, 75, e50477. (doi: 10.3791/50477) (PMID:23748878) (PMCID:PMC3720120)
Thellung, S., Gatta, E., Pellistri, F., Corsaro, A., Villa, V., Vassalli, M. , Robello, M. and Florio, T. (2013) Excitotoxicity through NMDA receptors mediates cerebellar granule neuron apoptosis induced by prion protein 90-231 fragment. Neurotoxicity Research, 23, pp. 301-314. (doi: 10.1007/s12640-012-9340-9) (PMID:22855343)
Chiarpotto, M. et al. (2013) Mechanism of aluminium bio-mineralization in the apoferritin cavity. Applied Physics Letters, 103(8), 083701. (doi: 10.1063/1.4818749)
Fanelli, D., McKane, A.J., Pompili, G., Tiribilli, B., Vassalli, M. and Biancalani, T. (2013) Diffusion of two molecular species in a crowded environment: theory and experiments. Physical Biology, 10(4), 045008. (doi: 10.1088/1478-3975/10/4/045008) (PMID:23912053)
Gavazzo, P., Vassalli, M. , Costa, D. and Pagano, A. (2013) Novel ncRNAs transcribed by Pol III and elucidation of their functional relevance by biophysical approaches. Frontiers in Cellular Neuroscience, 7, 203. (doi: 10.3389/fncel.2013.00203)
Greco, G., Svaldo Lanero, T., Torrassa, S., Young, R., Vassalli, M. , Cavaliere, A., Rolandi, R., Pelucchi, E., Faimali, M. and Davenport, J. (2013) Microtopography of the eye surface of the crab Carcinus maenas: an atomic force microscope study suggesting a possible antifouling potential. Journal of the Royal Society: Interface, 10, 20130122. (doi: 10.1098/rsif.2013.0122)
Marasini, C., Jacchetti, E., Moretti, M., Canale, C., Moran, O. and Vassalli, M. (2013) Visualization of single proteins from stripped native cell membranes: a protocol for high-resolution atomic force microscopy. Microscopy Research and Technique, 76(7), pp. 723-732. (doi: 10.1002/jemt.22223) (PMID:23681761)
Galante, D., Corsaro, A., Florio, T., Vella, S., Pagano, A., Sbrana, F., Vassalli, M. , Perico, A. and D'Arrigo, C. (2012) Differential toxicity, conformation and morphology of typical initial aggregation states of Aβ1-42 and Aβpy3-42 beta-amyloids. International Journal of Biochemistry and Cell Biology, 44(11), pp. 2085-2093. (doi: 10.1016/j.biocel.2012.08.010)
Mescola, A., Vella, S., Scotto, M., Gavazzo, P., Canale, C., Diaspro, A., Pagano, A. and Vassalli, M. (2012) Probing cytoskeleton organisation of neuroblastoma cells with single-cell force spectroscopy. Journal of Molecular Recognition, 25(5), pp. 270-277. (doi: 10.1002/jmr.2173) (PMID:22528188)
Sbrana, F., Fotia, C., Bracalello, A., Baldini, N., Marletta, G., Ciapetti, G., Bochicchio, B. and Vassalli, M. (2012) Multiscale characterization of a chimeric biomimetic polypeptide for stem cell culture. Bioinspiration and Biomimetics, 7(4), 046007. (doi: 10.1088/1748-3182/7/4/046007)
Basso, M., Paoletti, P., Tiribilli, B. and Vassalli, M. (2011) AFM imaging via nonlinear control of self-driven cantilever oscillations. IEEE Transactions on Nanotechnology, 10(3), pp. 560-565. (doi: 10.1109/TNANO.2010.2051815)
Bracalello, A., Santopietro, V., Vassalli, M. , Marletta, G., Del Gaudio, R., Bochicchio, B. and Pepe, A. (2011) Design and production of a chimeric resilin-, elastin-, and collagen-like engineered polypeptide. Biomacromolecules, 12(8), pp. 2957-2965. (doi: 10.1021/bm2005388) (PMID:21707089)
Guiggiani, A., Torre, B., Contestabile, A., Benfenati, F., Basso, M., Vassalli, M. and Difato, F. (2011) Long-range and long-term interferometric tracking by static and dynamic force-clamp optical tweezers. Optics Express, 19(23), pp. 22364-22376. (doi: 10.1364/OE.19.022364)
Marchetti, S., Sbrana, F., Toscano, A., Fratini, E., Carlà, M., Vassalli, M. , Tiribilli, B., Pacini, A. and Gambi, C.M.C. (2011) β-connectin studies by small-angle x-ray scattering and single-molecule force spectroscopy by atomic force microscopy. Physical Review E, 83, 051919. (doi: 10.1103/PhysRevE.83.051919) (PMID:21728583)
Paoletti, P., Basso, M., Pini, V., Tiribilli, B. and Vassalli, M. (2011) Self-driven soft imaging in liquid by means of photothermal excitation. Journal of Applied Physics, 110, 114315. (doi: 10.1063/1.3665396)
Pini, V., Tiribilli, B., Gambi, C. M. C. and Vassalli, M. (2011) Erratum: Dynamical characterization of vibrating AFM cantilevers forced by photothermal excitation (vol 81, 054302, 2010). Physical Review B, 83, 179904. (doi: 10.1103/PhysRevB.83.179904)
Sbrana, F., Lorusso, M., Canale, C., Bochicchio, B. and Vassalli, M. (2011) Effect of chemical cross-linking on the mechanical properties of elastomeric peptides studied by single molecule force spectroscopy. Journal of Biomechanics, 44(11), pp. 2118-2122. (doi: 10.1016/j.jbiomech.2011.05.028)
Monaldi, I., Vassalli, M. , Bachi, A., Giovedi, S., Millo, E., Valtorta, F., Raiteri, R., Benfenati, F. and Fassio, A. (2010) The highly conserved synapsin domain E mediates synapsin dimerization and phospholipid vesicle clustering. Biochemical Journal, 426(1), pp. 55-64. (doi: 10.1042/BJ20090762) (PMID:19922412)
Pini, V., Tiribilli, B., Gambi, C. M. C. and Vassalli, M. (2010) Dynamical characterization of vibrating AFM cantilevers forced by photothermal excitation. Physical Review B, 81, 054302. (doi: 10.1103/PhysRevB.81.054302)
Sbrana, F., Fanelli, D., Vassalli, M. , Carresi, L., Scala, A., Pazzagli, L., Cappugi, G. and Tiribilli, B. (2010) Progressive pearl necklace collapse mechanism for cerato-ulmin aggregation film. European Biophysics Journal with Biophysics Letters, 39, pp. 971-977. (doi: 10.1007/s00249-009-0465-6) (PMID:19471919)
Vassalli, M. , Pini, V. and Tiribilli, B. (2010) Role of the driving laser position on atomic force microscopy cantilevers excited by photothermal and radiation pressure effects. Applied Physics Letters, 97, 143105. (doi: 10.1063/1.3497074)
Basso, M., Paoletti, P., Tiribilli, B. and Vassalli, M. (2008) Modelling and analysis of autonomous micro-cantilever oscillations. Nanotechnology, 19(47), 475501. (doi: 10.1088/0957-4484/19/47/475501)
Becucci, L., Innocenti, M., Salvietti, E., Rindi, A., Pasquini, I., Vassalli, M. , Foresti, M. L. and Guidelli, R. (2008) Potassium ion transport by gramicidin and valinomycin across a Ag(111)-supported tethered bilayer lipid membrane. Electrochimica Acta, 53(22), pp. 6372-6379. (doi: 10.1016/j.electacta.2008.04.043)
Imparato, A., Sbrana, F. and Vassalli, M. (2008) Reconstructing the free-energy landscape of a polyprotein by single-molecule experiments. EPL (Europhysics Letters), 82(5), 58006. (doi: 10.1209/0295-5075/82/58006)
Marchetti, S., Sbrana, F., Raccis, R., Lanzi, L., Gambi, C.M.C., Vassalli, M. , Tiribilli, B., Pacini, A. and Toscano, A. (2008) Dynamic light scattering and atomic force microscopy imaging on fragments of beta-connectin from human cardiac muscle. Physical Review E, 77, 021910. (doi: 10.1103/PhysRevE.77.021910)
Papi, M., Maulucci, G., Arcovito, G., Paoletti, P., Vassalli, M. and De Spirito, M. (2008) Detection of microviscosity by using uncalibrated atomic force microscopy cantilevers. Applied Physics Letters, 93, 124102. (doi: 10.1063/1.2970963)
Sbrana, F., Bongini, L., Cappugi, G., Fanelli, D., Guarino, A., Pazzagli, L., Scala, A., Vassalli, M. , Zoppi, C. and Tiribilli, B. (2007) Atomic force microscopy images suggest aggregation mechanism in cerato-platanin. European Biophysics Journal with Biophysics Letters, 36, pp. 727-732. (doi: 10.1007/s00249-007-0159-x)
Giannini, R., Vassalli, M. , Chellini, F., Polidori, L., Dei, R. and Giannelli, M. (2006) Neodymium:yttrium aluminum garnet laser irradiation with low pulse energy: a potential tool for the treatment of peri-implant disease. Clinical Oral Implants Research, 17(6), pp. 638-643. (doi: 10.1111/j.1600-0501.2006.01278.x) (PMID:17092221)
Papi, M., Arcovito, G., De Spirito, M., Vassalli, M. and Tiribilli, B. (2006) Fluid viscosity determination by means of uncalibrated atomic force microscopy cantilevers. Applied Physics Letters, 88, 194102. (doi: 10.1063/1.2200588)
Quercioli, F., Tiribilli, B., Vassalli, M. and Sbrana, F. (2006) Autocorrelator designs for nonlinear optical microscopy. Optical Engineering, 45(6), 064303. (doi: 10.1117/1.2215379)
Grilli, S., Ferraro, P., De Natale, P., Tiribilli, B. and Vassalli, M. (2005) Surface nanoscale periodic structures in congruent lithium niobate by domain reversal patterning and differential etching. Applied Physics Letters, 87(23), 233106. (doi: 10.1063/1.2137877)
Tiribilli, B., Bani, D., Quercioli, F., Ghirelli, A. and Vassalli, M. (2005) Atomic force microscopy of histological sections using a chemical etching method. Ultramicroscopy, 102(3), pp. 227-232. (doi: 10.1016/j.ultramic.2004.10.003) (PMID:15639354)
Quercioli, F., Tiribilli, B. and Vassalli, M. (2004) Wavefront-division lateral shearing autocorrelator for ultrafast laser microscopy. Optics Express, 12(18), pp. 4303-4312. (doi: 10.1364/OPEX.12.004303) (PMID:19483977)
Quercioli, F., Tiribilli, B., Vassalli, M. and Ghirelli, A. (2004) Laser spectral characterization in multiphoton microscopy. Applied Optics, 43(15), pp. 3055-3060. (doi: 10.1364/AO.43.003055) (PMID:15176192)
Formigli, L. et al. (2004) Sphingosine 1-phosphate induces cell contraction via calcium-independent/Rho-dependent pathways in undifferentiated skeletal muscle cells. Journal of Cellular Physiology, 198(1), pp. 1-11. (doi: 10.1002/jcp.10366) (PMID:14584038)
Nosi, D., Vassalli, M. , Polidori, L., Giannini, R., Tani, A., Chellini, F. and Paternostro, F. (2004) Effects of S1P on myoblastic cell contraction: Possible involvement of Ca2+-independent mechanisms. Cells Tissues Organs, 178(3), pp. 129-138. (doi: 10.1159/000082243) (PMID:15655330)
Quercioli, F., Ghirelli, A., Tiribilli, B. and Vassalli, M. (2004) Ultracompact autocorrelator for multiphoton microscopy. Microscopy Research and Technique, 63(1), pp. 27-33. (doi: 10.1002/jemt.10420) (PMID:14677131)
Bencini, C. et al. (2003) Effects of sphingosine 1-phosphate on excitation–contraction coupling in mammalian skeletal muscle. Journal of Muscle Research and Cell Motility, 24(8), pp. 539-554. (doi: 10.1023/B:JURE.0000009898.02325.58) (PMID:14870969)
Vassalli, M. and Giannelli, M. (2003) Effect of Nd: YAG laser on titanium dental implants studied by AFM. Italian Journal of Anatomy and Embryology, 108(4), pp. 195-203. (PMID:14974502)
Buah-Bassuah, P. K., Tiribilli, B., Vassalli, M. and Molesini, G. (2003) Simple portable lens meter. Applied Optics, 42(25), pp. 5086-5090. (doi: 10.1364/AO.42.005086) (PMID:12962384)
Formigli, L. et al. (2002) Sphingosine 1-phosphate induces Ca2+ transients and cytoskeletal rearrangement in C2C12 myoblastic cells. American Journal of Physiology: Cell Physiology, 282(6), C1361-C1373. (doi: 10.1152/ajpcell.00378.2001) (PMID:11997251)
Francini, F. et al. (2002) Ca2+ homeostasis and cytoskeletal rearrangement operated by sphingosine 1-phosphate in C2C12 myoblastic cells. Journal of Gravitational Physiology, 9(1), P281-P282. (PMID:15002581)
Bartoli, A., Poggi, P., Quercioli, F., Tiribilli, B. and Vassalli, M. (2001) Optical profilometer with a standalone scanning sensor head. Optical Engineering, 40(12), pp. 2852-2859. (doi: 10.1117/1.1417494)
Giacomelli, G., Hegger, R., Politi, A. and Vassalli, M. (2000) Convective Lyapunov exponents and propagation of correlations. Physical Review Letters, 85(17), 3616. (doi: 10.1103/PhysRevLett.85.3616)
Giardinà, C., Livi, R., Politi, A. and Vassalli, M. (2000) Finite thermal conductivity in 1D lattices. Physical Review Letters, 84(10), 2144. (doi: 10.1103/PhysRevLett.84.2144)
Book Sections
Caponi, S., Canale, C., Cavalleri, O. and Vassalli, M. (2019) Characterization tools for mechanical probing of biomimetic materials. In: Kumar, Challa S.S.R. (ed.) Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy. Springer, pp. 69-111. ISBN 9783662595954 (doi: 10.1007/978-3-662-59596-1_2)
Conference or Workshop Item
Soloperto, A., Bartolozzi, A., Palazzolo, G., Basso, M., Contestabile, A., Vassalli, M. and Difato, F. (2016) Expression and Biophysical Characterization of Bacterial Mechano-Sensitive Ion Channel of Large Conductance into Mammalian Cells. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, USA, 27 Feb - 02 Mar 2016.
Cipolla, L., Russo, L., Sgambato, A., Guizzardi, R., Lecchi, M., Pastori, V., Petecchia, L., Gavazzo, P. and Vassalli, M. (2016) Effects of neoglycosylated collagen matrices on neuroblastoma and human stem cells: a new perspective for neuro-regeneration? Second International Meeting of the Milan Center for Neuroscience (Neuromi): Prediction and Prevention of Dementia: New Hope, Milan, Italy, 06-08 Jul 2016.
Asnaghi, V. et al. (2015) Risk-monitoring, Modelling and Mitigation (M3-HABs) of Benthic Microalgal Blooms across Mediterranean Region. Sixth European Phycological Congress, London, UK, 23-28 Aug 2015.
Randazzo, L.A., Santangelo, M.G., Noto, R., Vassalli, M. , Manno, M. and Martorana, V. (2015) Protein Diffusion, Stability and Activity in Crowded Media. 10th European-Biophysical-Societies-Association (EBSA) European Biophysics Congress, Dresden, Germany, 18-22 Jul 2015.
Corsaro, A., Raccosta, S., De Stefano, S., Thellung, S., Villa, V., Manno, M., Martorana, V., Vassalli, M. and Florio, T. (2014) Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements. International Prion Congress, Trieste, Italy, 27-30 May 2014.
Marasini, C. and Vassalli, M. (2011) Direct Visualization of CFTR Conformation by Atomic Force Microscopy Imaging. 8th EBSA European Biophysics Congress, Budapest, Hungary, 23-27 Aug 2011.
Conference Proceedings
Cacace, T., Paturzo, M., Memmolo, P., Vassalli, M. , Fraldi, M., Mensitieri, G. and Ferraro, P. (2017) Investigation on Microfluidic Particles Manipulation by Holographic 3D Tracking Strategies. In: SPIE Optical Metrology, Munich, Germany, 24-27 Jun 2019, (doi: 10.1117/12.2271829)
Scaglione, S., Barenghi, R., Beke, S., Ceseracciu, L., Romano, I., Sbrana, F., Stagnaro, P., Brandi, F. and Vassalli, M. (2013) Characterization of a Bioinspired Elastin-Polypropylene Fumarate Material for Vascular Prostheses Applications. In: SPIE Optical Metrology 2013, Munich, Germany, 13-16 May 2013, 87920H. (doi: 10.1117/12.2021754)
Difato, F., Tsushima, H., Pesce, M., Guiggiani, A., Benfenati, F., Blau, A., Basso, M., Vassalli, M. and Chieregatti, E. (2012) Axonal Regeneration of Cultured Mouse Hippocampal Neurons Studied by an Optical Nano-surgery System. In: SPIE BiOS 2012, San Francisco, CA, USA, 21-26 Jan 2012, p. 820760. (doi: 10.1117/12.908345)
Basso, M., Paoletti, P., Tiribilli, B. and Vassalli, M. (2009) Modeling and Analysis of Auto-tapping AFM. In: 47th IEEE Conference on Decision and Control, Cancun, Mexico, 09-11 Dec 2008, pp. 5188-5193. ISBN 9781424431236 (doi: 10.1109/CDC.2008.4739214)
Basso, M., Bucher, R., Romagnoli, M. and Vassalli, M. (2006) Real-time Lontrol with Linux: A Web Services Approach. In: 44th IEEE Conference on Decision and Control, 2005 and 2005 European Control Conference. CDC-ECC '05., Seville, Spain, 12-15 December 2005, pp. 2733-2738. ISBN 0780395670 (doi: 10.1109/CDC.2005.1582576)
Tiribilli, B., Ferraro, P., Grilli, S., Molesini, G., Vannoni, M. and Vassalli, M. (2006) An Integrated Approach for Photonic Crystal Inspection and Characterization. In: SPIE Photonics Europe, Strasbourg, France, 03-07 Apr 2006, 61880A. (doi: 10.1117/12.664930)
Grilli, S., Ferraro, P., Sansone, L., Tiribilli, B., Vassalli, M. and De Natale, P. (2005) Fabrication of 2D Sub-micron Structures in Lithium Niobate for Photonic Crystal Applications. In: Optics and Photonics 2005, San Diego, CA, USA, 31 Jul - 04 Aug 2005, p. 593107. (doi: 10.1117/12.617106)
Pelli, S., Righini, G.C., Quercioli, F., Tiribilli, B., Vassalli, M. , Cremona, M. and Pereira, J.A.M. (2004) Optical Waveguides in LiF by Ion-beam Irradiation: Fabrication and Characterisation. In: 2003 Conference on Lasers and Electro-Optics Europe (CLEO/Europe 2003), Munich, Germany, 22-27 Jun 2003, p. 682. ISBN 0780377346 (doi: 10.1109/CLEOE.2003.1313740)
Quercioli, F., Ghirelli, A., Tiribilli, B. and Vassalli, M. (2004) Autocorrelator for Multiphoton Microscopy. In: Photonics Europe, Strasbourg, France, 2004, pp. 162-170. (doi: 10.1117/12.544609)
Pelli, S., Brenci, M., Calzolai, R., Quercioli, F., Tiribilli, B., Vassalli, M. , Ghirelli, A., Cremona, M., Pereira, J.A.M. and Righini, G.C. (2003) Confocal Luminescence Microscopy Characterization of Optical Waveguides Produced by Ion Beam Irradiation on LiF. In: Integrated Optoelectronics Devices, San Jose, CA, USA, 2003, pp. 13-20. (doi: 10.1117/12.478329)
Quercioli, F., Tiribilli, B., Vassalli, M. , Ghirelli, A., Righini, G., Pelli, S. and Cremona, M. (2003) Confocal Microscopy for the Testing of Integrated Optical Devices. In: 19th Congress of the International Commission for Optics: Optics for the Quality of Life, Florence, Italy, 2002, pp. 665-667. (doi: 10.1117/12.527040)
Exhibitions
Keith, N. et al. (2023) Regenerative Futures: From Global to Local Development in 2032. [Exhibitions]
Grants
- 2023-2025 Leverhulme Trust, "Multicomponent Gel Noodles for New Textiles and Fabrics", with Dave Adams
- 2022-2027 UKRI guarantee funding / EIC Pathfinder Challenge, "PRISM-LT", with Chalmers, Radboud, CellInk, IN Society
- 2020-2023 Royal Society, "Novel tools for mechanobiology: from Atomic Force Microscopy to Brillouin spectroscopy", with the Ghost Lab
Supervision
- Afxenti, Ivi
Biphotons for nonlinear imaging - Isakova, Julia
Developing RAMAN-based methodology to investigate cell glycosylation signatures - Purdie, Euan
Exploiting metabolite GPCR mechanotransduction to find new treatments for metabolic disorders
Teaching
I'm currently involved in the following courses:
- ENG2012: Biomed Engineering Skills 2
- ENG2087: Engineering in Biology 2
- ENG3090: Biomed Engineering Skills 3
- ENG4200: Introduction to Artificial Intelligence and Machine Learning 4
- ENG5337: Advanced Artificial Intelligence and Machine Learning 5
If you have any query related to teaching on these courses, feel free to contact me via email.
Professional activities & recognition
Research fellowships
- 2016 - 2016: Endeavour Research Fellowship, Australian Government
- 2014 - 2014: Swiss National Science Foundation
Grant committees & research advisory boards
- 2014: FABCrea, President of the advisory board
- 2018 - 2019: Regional life science pole (PLSV), Liguria, Italy, Scientific Board
- 2016 - 2018: Regional Biotechnology Pole, Liguria, Italy, Scientific board
Editorial boards
- 2016: Scientific Reports
- 2018: Biophysical Reviews
Professional & learned societies
- 2018 - 2020: Secretary, Italian Society for Pure and Applied Biophysics
- 2016 - 2018: Member, Optical Society of America
- 2014 - 2017: Member, Italian Society of Physics
- 2014 - 2016: Secretary, Italian Society for Pure and Applied Biophysics
- 2012 - 2020: Member, Italian Society for Pure and Applied Biophysics
- 2019: Member, British Biophysical Society
- 2019: Member, Institute of Physics
Selected international presentations
- 2018: Invited Lecturer at the International Biophysics School "Academician Radoslav K.Andjus" (NERKA) on Mechanobiology (Kotor, Montenegro)
- 2018: Plenary speaker at the Regional Biophysics Conference (Zrece, Slovenia)
- 2017: Technical Lecturer at the International School on Computational Microscopy (Amalfi, Italy)
- 2015: Invited lecturer at the Nano-bio imaging workshop (Bologna, Italy)
- 2014: Invited lecturer at the Fall Meeting of the European Materials Research Society (Warsaw, Poland)
Research datasets
2025
Binner, P., Starshynov, I. , Tejeda, G. , McFall, A. , CICCONE, G., Walker, M. , Vassalli, M. , Tobin, A. and Faccio, D. (2025) Optical, contact-free assessment of brain tissue stiffness and neurodegeneration. [Data Collection]
2021
Oropesa-Nuñez, R., Mescola, A., Vassalli, M. and Canale, C. (2021) Impact of experimental parameters on cell-cell force spectroscopy signature. [Data Collection]
2020
Orapiriyakul, W., Tsimbouri, M. , Childs, P., Campsie, P., Wells, J., Fernandez-Yague, M. A., Burgess, K., Tanner, E., Tassieri, M. , Meek, D., Vassalli, M. , Biggs, M. J.P., Salmeron-Sanchez, M. , Oreffo, R. O. C., Reid, S. and Dalby, M. (2020) Nanovibrational Stimulation of Mesenchymal Stem Cells Induces Therapeutic Reactive Oxygen Species and Inflammation for Three- Dimensional Bone Tissue Engineering. [Data Collection]
Lüchtefeld, I., Bartolozzi, A., Mejiá, J., Dobre, O. , Basso, M., Zambelli, T. and Vassalli, M. (2020) Elasticity Spectra as a Tool to Investigate Actin Cortex Mechanics. [Data Collection]
Hodgkinson, T., Tsimbouri, M. , Llopis-Hernandez, V. , Campsie, P., Scurr, D., Childs, P., Phillips, D. , Donnelly, S., Wells, J., Salmeron-Sanchez, M. , Burgess, K., Alexander, M., Vassalli, M. , Oreffo, R., Reid, S., France, D. and Dalby, M. (2020) Nanovibrational mesenchymal stem cell stimulation allows detection of highly osteo-specific bioactive metabolites that can be modified for enhanced potency. [Data Collection]
